Scott J. Hultgren
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American microbiologist
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Scott J. Hultgrenbiology Degrees
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Biology
Scott J. Hultgren's Degrees
- PhD Microbiology University of Washington
- Bachelors Microbiology University of Washington
Why Is Scott J. Hultgren Influential?
(Suggest an Edit or Addition)According to Wikipedia, Scott J. Hultgren is an American microbiologist who is currently a professor of molecular microbiology and director of the Center for Women's Infectious Diseases Research at Washington University in St. Louis. Since 2011, he has been a member of the National Academy of Sciences, and was elected a member of the National Academy of Medicine in 2017 along with 80 other new members. In December 2019 he was named Fellow of the National Academy of Inventors. In April 2023, he was elected into the American Academy of Arts & Sciences. He is the principal investigator at the Hultgren Lab at Washington University School of Medicine. in 1998 he was awarded the Eli Lilly Award for his work in the fields of microbiology and immunology, noting his work in producing a vaccine for urinary tract infections.
Scott J. Hultgren's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Urinary tract infections: epidemiology, mechanisms of infection and treatment options (2015) (2149)
- Role of Escherichia coli Curli Operons in Directing Amyloid Fiber Formation (2002) (1121)
- Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. (1999) (1109)
- Intracellular Bacterial Biofilm-Like Pods in Urinary Tract Infections (2003) (1038)
- Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. (1998) (964)
- Establishment of a Persistent Escherichia coli Reservoir during the Acute Phase of a Bladder Infection (2001) (759)
- The biology and future prospects of antivirulence therapies (2008) (738)
- Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. (2013) (730)
- Type 1 pilus‐mediated bacterial invasion of bladder epithelial cells (2000) (702)
- Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. (2004) (592)
- Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination. (1997) (589)
- X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli. (1999) (586)
- Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. (2006) (566)
- Detection of Intracellular Bacterial Communities in Human Urinary Tract Infection (2007) (551)
- Morphological plasticity as a bacterial survival strategy (2008) (520)
- Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract (2006) (474)
- Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses. (2000) (463)
- Bacterial Adhesins: Common Themes and Variations in Architecture and Assembly (1999) (463)
- Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition (1993) (431)
- FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae. (1995) (425)
- Structural basis of chaperone function and pilus biogenesis. (1999) (413)
- Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. (2009) (384)
- Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection (2002) (382)
- Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili (2007) (317)
- P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips (1992) (316)
- Multiple pathways allow protein secretion across the bacterial outer membrane. (2000) (315)
- Vaccination with FimH adhesin protects cynomolgus monkeys from colonization and infection by uropathogenic Escherichia coli. (2000) (314)
- Filamentation by Escherichia coli subverts innate defenses during urinary tract infection (2006) (309)
- A murine model of urinary tract infection (2009) (306)
- Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. (2012) (305)
- Receptor binding studies disclose a novel class of high‐affinity inhibitors of the Escherichia coli FimH adhesin (2004) (305)
- Structural biology of the chaperone–usher pathway of pilus biogenesis (2009) (295)
- Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria (2006) (293)
- Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. (2004) (290)
- Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors (2011) (265)
- Chaperone Priming of Pilus Subunits Facilitates a Topological Transition that Drives Fiber Formation (2002) (260)
- The chaperone‐assisted membrane release and folding pathway is sensed by two signal transduction systems (1997) (254)
- Structural Basis of the Interaction of the Pyelonephritic E. coli Adhesin to Its Human Kidney Receptor (2001) (250)
- Bacterial Invasion Augments Epithelial Cytokine Responses to Escherichia coli Through a Lipopolysaccharide-Dependent Mechanism1 (2001) (247)
- Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex (2008) (240)
- Chaperone-assisted assembly and molecular architecture of adhesive pili. (1991) (238)
- Fiber Formation across the Bacterial Outer Membrane by the Chaperone/Usher Pathway (2008) (230)
- Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection (2010) (227)
- Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG (2014) (226)
- Uropathogenic Escherichia coli Flagella Aid in Efficient Urinary Tract Colonization (2005) (223)
- Bacterial pili: molecular mechanisms of pathogenesis. (2000) (218)
- The chaperone/usher pathway: a major terminal branch of the general secretory pathway. (1998) (217)
- Molecular Regulation of Urothelial Renewal and Host Defenses during Infection with Uropathogenic Escherichia coli * 210 (2002) (216)
- Fiber assembly by the chaperone-usher pathway. (2004) (215)
- Secretion of curli fibre subunits is mediated by the outer membrane‐localized CsgG protein (2006) (214)
- Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli (2009) (213)
- Structural basis of pilus subunit recognition by the PapD chaperone. (1993) (212)
- Structure-based drug design and optimization of mannoside bacterial FimH antagonists. (2010) (205)
- Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli (2003) (205)
- Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes. (1993) (202)
- Regulation of production of type 1 pili among urinary tract isolates of Escherichia coli (1986) (197)
- Role of type 1 pili and effects of phase variation on lower urinary tract infections produced by Escherichia coli (1985) (191)
- Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist (2017) (190)
- Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate (2011) (189)
- Cpx signaling pathway monitors biogenesis and affects assembly and expression of P pili (2001) (188)
- Bacterial Exposure Induces and Activates Matrilysin in Mucosal Epithelial Cells (2000) (184)
- Escherichia coli Biofilms Have an Organized and Complex Extracellular Matrix Structure (2013) (181)
- Molecular basis of two subfamilies of immunoglobulin‐like chaperones. (1996) (179)
- Escherichia coli from Urine of Female Patients with Urinary Tract Infections Is Competent for Intracellular Bacterial Community Formation (2006) (179)
- A tale of two pili: assembly and function of pili in bacteria. (2010) (174)
- PapD-like chaperones provide the missing information for folding of pilin proteins. (2000) (173)
- Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding (2009) (172)
- Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. (2006) (170)
- The PapC usher forms an oligomeric channel: implications for pilus biogenesis across the outer membrane. (1998) (166)
- Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. (2004) (165)
- CD14- and Toll-Like Receptor-Dependent Activation of Bladder Epithelial Cells by Lipopolysaccharide and Type 1 Piliated Escherichia coli (2003) (164)
- The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. (2005) (163)
- Effect of Trimethoprim-Sulfamethoxazole on Recurrent Bacteriuria and Bacterial Persistence in Mice Infected with Uropathogenic Escherichia coli (2002) (163)
- Secretion of virulence determinants by the general secretory pathway in gram-negative pathogens: an evolving story. (2000) (162)
- The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus. (1989) (162)
- Ramifications of kinetic partitioning on usher‐mediated pilus biogenesis (1998) (160)
- Functional Genomic Studies of Uropathogenic Escherichia coli and Host Urothelial Cells when Intracellular Bacterial Communities Are Assembled* (2007) (154)
- Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies (2020) (153)
- Requirement of Rho‐family GTPases in the invasion of Type 1‐piliated uropathogenic Escherichia coli (2002) (152)
- The mechanical properties of E. coli type 1 pili measured by atomic force microscopy techniques. (2006) (150)
- Utilization of an Intracellular Bacterial Community Pathway in Klebsiella pneumoniae Urinary Tract Infection and the Effects of FimK on Type 1 Pilus Expression (2008) (147)
- Update on biofilm infections in the urinary tract (2012) (145)
- Periplasmic Peptidyl Prolyl cis-trans Isomerases Are Not Essential for Viability, but SurA Is Required for Pilus Biogenesis in Escherichia coli (2005) (144)
- Chaperone-assisted pilus assembly and bacterial attachment. (2000) (144)
- PapD chaperone function in pilus biogenesis depends on oxidant and chaperone-like activities of DsbA. (1994) (143)
- Relationship of type 1 pilus expression in Escherichia coli to ascending urinary tract infections in mice (1987) (143)
- Suppression of Bladder Epithelial Cytokine Responses by Uropathogenic Escherichia coli (2005) (142)
- Contribution of Autolysin and Sortase A during Enterococcus faecalis DNA-Dependent Biofilm Development (2009) (142)
- Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF (2009) (140)
- Enterococcal Biofilm Formation and Virulence in an Optimized Murine Model of Foreign Body-Associated Urinary Tract Infections (2010) (139)
- Initiation of assembly and association of the structural elements of a bacterial pilus depend on two specialized tip proteins. (1993) (139)
- QseC‐mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli (2009) (135)
- Bacterial amyloid formation: structural insights into curli biogensis. (2015) (132)
- Population Dynamics and Niche Distribution of Uropathogenic Escherichia coli during Acute and Chronic Urinary Tract Infection (2011) (129)
- CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation (2011) (126)
- G‐CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity (2008) (125)
- Enterococcus faecalis Tropism for the Kidneys in the Urinary Tract of C57BL/6J Mice (2005) (125)
- Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli (2001) (125)
- FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria. (1993) (124)
- EbpA vaccine antibodies block binding of Enterococcus faecalis to fibrinogen to prevent catheter-associated bladder infection in mice (2014) (123)
- Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits. (1991) (121)
- Genomic Diversity and Fitness of E. coli Strains Recovered from the Intestinal and Urinary Tracts of Women with Recurrent Urinary Tract Infection (2013) (121)
- PapD, a periplasmic transport protein in P-pilus biogenesis (1989) (120)
- Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection (2015) (119)
- A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. (2013) (119)
- Chaperone-assisted self-assembly of pili independent of cellular energy. (1994) (118)
- Maturation of Intracellular Escherichia coli Communities Requires SurA (2006) (118)
- Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women. (2009) (118)
- Structure and function of Escherichia coli type 1 pili: new insight into the pathogenesis of urinary tract infections. (2001) (112)
- Interactive surface in the PapD chaperone cleft is conserved in pilus chaperone superfamily and essential in subunit recognition and assembly. (1992) (110)
- Polysaccharide Capsule and Sialic Acid-Mediated Regulation Promote Biofilm-Like Intracellular Bacterial Communities during Cystitis (2010) (108)
- Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. (2009) (108)
- Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections. (2016) (106)
- Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. (2011) (106)
- A central metabolic circuit controlled by QseC in pathogenic Escherichia coli (2011) (105)
- Urinary Tract Infection as a Preventable Cause of Pregnancy Complications: Opportunities, Challenges, and a Global Call to Action (2013) (105)
- Conserved immunoglobulin‐like features in a family of periplasmic pilus chaperones in bacteria. (1992) (105)
- Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections (2017) (105)
- Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. (2012) (104)
- The Legionella pneumophila PilT Homologue DotB Exhibits ATPase Activity That Is Critical for Intracellular Growth (2004) (104)
- Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus (1998) (103)
- The Metal Ion-Dependent Adhesion Site Motif of the Enterococcus faecalis EbpA Pilin Mediates Pilus Function in Catheter-Associated Urinary Tract Infection (2012) (103)
- Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. (2004) (100)
- Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates α-Synuclein Fibrillation (2012) (99)
- Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation (2013) (99)
- Snapshots of usher-mediated protein secretion and ordered pilus assembly. (2000) (97)
- Combinatorial Small-Molecule Therapy Prevents Uropathogenic Escherichia coli Catheter-Associated Urinary Tract Infections in Mice (2012) (96)
- Structural and energetic basis of folded protein transport by the FimD usher (2013) (92)
- Mechanism for Sortase Localization and the Role of Sortase Localization in Efficient Pilus Assembly in Enterococcus faecalis (2009) (92)
- Host subversion by formation of intracellular bacterial communities in the urinary tract. (2004) (89)
- Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. (2010) (89)
- Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract. (2006) (88)
- Interaction of uropathogenic Escherichia coli with host uroepithelium. (2005) (85)
- Bacterial Outer Membrane Ushers Contain Distinct Targeting and Assembly Domains for Pilus Biogenesis (2002) (83)
- Escherichia coli DegP Protease Cleaves between Paired Hydrophobic Residues in a Natural Substrate: the PapA Pilin (2002) (83)
- Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis (2014) (83)
- Molecular Variations in Klebsiella pneumoniae and Escherichia coli FimH Affect Function and Pathogenesis in the Urinary Tract (2008) (82)
- Virulence Plasmid Harbored by Uropathogenic Escherichia coli Functions in Acute Stages of Pathogenesis (2010) (81)
- Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor (2013) (79)
- Transposon Mutagenesis Identifies Uropathogenic Escherichia coli Biofilm Factors (2012) (78)
- Metabolic Requirements of Escherichia coli in Intracellular Bacterial Communities during Urinary Tract Infection Pathogenesis (2016) (78)
- Adhesive Pili in UTI Pathogenesis and Drug Development (2016) (76)
- Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract (2017) (76)
- Dynamic interactions between host and pathogen during acute urinary tract infections. (2001) (75)
- Enterococcus faecalis Overcomes Foreign Body-Mediated Inflammation To Establish Urinary Tract Infections (2012) (74)
- Molecular mechanism of P pilus termination in uropathogenic Escherichia coli (2006) (70)
- LeuX tRNA‐dependent and ‐independent mechanisms of Escherichia coli pathogenesis in acute cystitis (2007) (70)
- Crystal Structure of the P Pilus Rod Subunit PapA (2007) (68)
- Immune Activation and Suppression by Group B Streptococcus in a Murine Model of Urinary Tract Infection (2011) (67)
- Targeting virulence for antimicrobial chemotherapy. (2003) (67)
- Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis (2013) (66)
- Precision antimicrobial therapeutics: the path of least resistance? (2018) (66)
- From Physiology to Pharmacy: Developments in the Pathogenesis and Treatment of Recurrent Urinary Tract Infections (2013) (66)
- PapD-like chaperones and pilus biogenesis. (2000) (66)
- Assembly of complex organelles: pilus biogenesis in gram-negative bacteria as a model system. (2000) (66)
- A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease (2016) (64)
- Chaperone-Subunit-Usher Interactions Required for Donor Strand Exchange during Bacterial Pilus Assembly (2003) (64)
- Probing of the combining site of the PapG adhesin of uropathogenic Escherichia coli bacteria by synthetic analogs of galabiose (1989) (63)
- Streptozocin-Induced Diabetic Mouse Model of Urinary Tract Infection (2008) (63)
- The E. coli CsgB nucleator of curli assembles to β-sheet oligomers that alter the CsgA fibrillization mechanism (2012) (63)
- Design and parallel solid-phase synthesis of ring-fused 2-pyridinones that target pilus biogenesis in pathogenic bacteria. (2002) (62)
- Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma (2019) (62)
- Pilus biogenesis via the chaperone/usher pathway: an integration of structure and function. (1998) (61)
- Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli (2014) (61)
- Adhesin presentation in bacteria requires molecular chaperones and ushers (1992) (61)
- Structural requirements for the glycolipid receptor of human uropathogenic Escherichia coli (1995) (59)
- Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity (2015) (59)
- Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper. (1996) (58)
- Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection (2018) (58)
- Immune Modulation by Group B Streptococcus Influences Host Susceptibility to Urinary Tract Infection by Uropathogenic Escherichia coli (2012) (57)
- Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling (2016) (57)
- Real-time and equilibrium 19F-NMR studies reveal the role of domain–domain interactions in the folding of the chaperone PapD (2002) (57)
- Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coli. (1993) (56)
- Pilin and Sortase Residues Critical for Endocarditis- and Biofilm-Associated Pilus Biogenesis in Enterococcus faecalis (2013) (56)
- Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli (2015) (56)
- Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions (2018) (55)
- Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes (2019) (55)
- AhrC and Eep Are Biofilm Infection-Associated Virulence Factors in Enterococcus faecalis (2013) (55)
- Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections (2016) (54)
- Characterization of a Novel Murine Model of Staphylococcus saprophyticus Urinary Tract Infection Reveals Roles for Ssp and SdrI in Virulence (2010) (54)
- Molecular blueprint of uropathogenic Escherichia coli virulence provides clues toward the development of anti-virulence therapeutics (2012) (53)
- The Widely Used Antimicrobial Triclosan Induces High Levels of Antibiotic Tolerance In Vitro and Reduces Antibiotic Efficacy up to 100-Fold In Vivo (2019) (52)
- Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection (2015) (50)
- Fibrinogen Release and Deposition on Urinary Catheters Placed during Urological Procedures. (2015) (49)
- Design, synthesis and evaluation of peptidomimetics based on substituted bicyclic 2-pyridones-targeting virulence of uropathogenic E. coli. (2006) (48)
- Catalysis of protein folding by chaperones in pathogenic bacteria. (2004) (48)
- Recognition of the N‐terminal lectin domain of FimH adhesin by the usher FimD is required for type 1 pilus biogenesis (2007) (46)
- Uropathogenic Escherichia coli Superinfection Enhances the Severity of Mouse Bladder Infection (2015) (46)
- Antibody-Based Therapy for Enterococcal Catheter-Associated Urinary Tract Infections (2016) (45)
- Haemophilus influenzae pili are composite structures assembled via the HifB chaperone. (1996) (44)
- Recent advances into the pathogenesis of recurrent urinary tract infections: the bladder as a reservoir for uropathogenic Escherichia coli. (2002) (44)
- Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides. (2003) (44)
- Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study. (2012) (43)
- Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI (2016) (43)
- Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection. (2016) (42)
- P Pilus Assembly Motif Necessary for Activation of the CpxRA Pathway by PapE in Escherichia coli (2004) (41)
- Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions (2017) (41)
- Distinguishing the Contribution of Type 1 Pili from That of Other QseB-Misregulated Factors when QseC Is Absent during Urinary Tract Infection (2012) (40)
- Multivariate design, synthesis, and biological evaluation of peptide inhibitors of FimC/FimH protein-protein interactions in uropathogenic Escherichia coli. (2005) (39)
- A Novel Endogenous Inhibitor of the Secreted Streptococcal NAD-Glycohydrolase (2005) (39)
- C-Terminal properties are important for ring-fused 2-pyridones that interfere with the chaperone function in uropathogenic E. coli. (2005) (39)
- Stable fiber-forming and nonfiber-forming chaperone-subunit complexes in pilus biogenesis. (1994) (38)
- Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection (2017) (38)
- The Catabolite Repressor Protein-Cyclic AMP Complex Regulates csgD and Biofilm Formation in Uropathogenic Escherichia coli (2016) (37)
- Probing conserved surfaces on PapD (1999) (37)
- Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis (2019) (36)
- Structure of the S pilus periplasmic chaperone SfaE at 2.2 A resolution. (2002) (36)
- The complex interactions of bacterial pathogens and host defenses. (2013) (36)
- PapD and superfamily of periplasmic immunoglobulin-like pilus chaperones. (1993) (36)
- Biogenesis of the bacterial pilus. (1991) (36)
- Reaching the End of the Line: Urinary Tract Infections. (2019) (36)
- Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions (2017) (35)
- The PapG tip adhesin of P fimbriae protects Escherichia coli from neutrophil bactericidal activity (1994) (35)
- Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine (2012) (35)
- Murine Vaginal Colonization Model for Investigating Asymptomatic Mucosal Carriage of Streptococcus pyogenes (2013) (34)
- Design and Synthesis of Fluorescent Pilicides and Curlicides: Bioactive Tools to Study Bacterial Virulence Mechanisms (2012) (33)
- Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection (2015) (33)
- Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli. (2008) (32)
- Establishment and Characterization of UTI and CAUTI in a Mouse Model. (2015) (32)
- Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria. (1994) (32)
- Fueling the Fire with Fibers: Bacterial Amyloids Promote Inflammatory Disorders. (2015) (32)
- Structural Homology between the C-Terminal Domain of the PapC Usher and Its Plug (2010) (31)
- Pilicides regulate pili expression in E. coli without affecting the functional properties of the pilus rod. (2007) (31)
- Systemic immunization with conserved pilus-associated adhesins protects against mucosal infections. (1998) (31)
- Structural basis of chaperone self-capping in P pilus biogenesis. (1999) (31)
- Bacterial adhesion--a source of alternate antibiotic targets. (2009) (30)
- Binding of Pili from UropathogenicEscherichia coli to Membranes Secreted by Human Colonocytes and Enterocytes (1999) (29)
- Down-Regulation of the kps Region 1 Capsular Assembly Operon following Attachment of Escherichia coli Type 1 Fimbriae to d-Mannose Receptors (2005) (29)
- Stereoselective synthesis of optically active beta-lactams, potential inhibitors of pilus assembly in pathogenic bacteria. (2000) (29)
- The Pilus Usher Controls Protein Interactions via Domain Masking and is Functional as an Oligomer (2015) (28)
- Significance of the d-Serine-Deaminase and d-Serine Metabolism of Staphylococcus saprophyticus for Virulence (2013) (27)
- Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner (2018) (27)
- A novel secretion apparatus for the assembly of adhesive bacterial pili. (1993) (27)
- Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF. (2008) (27)
- Structural basis of Streptococcus pyogenes immunity to its NAD+ glycohydrolase toxin. (2011) (27)
- Hydrogen Sulfide Sensing through Reactive Sulfur Species (RSS) and Nitroxyl (HNO) in Enterococcus faecalis. (2018) (27)
- Adaptor Function of PapF Depends on Donor Strand Exchange in P-Pilus Biogenesis of Escherichia coli (2007) (27)
- Mannose‐sensitive haemagglutination in the absence of piliation in Escherichia coli (1990) (27)
- Genetics of Adhesin Expression in Escherichia coli (1990) (26)
- Molecular dissection of PapD interaction with PapG reveals two chaperone‐binding sites (1995) (26)
- Impairment of the biomechanical compliance of P pili: a novel means of inhibiting uropathogenic bacterial infections? (2012) (26)
- Molecular basis of usher pore gating in Escherichia coli pilus biogenesis (2013) (26)
- The differential affinity of the usher for chaperone–subunit complexes is required for assembly of complete pili (2010) (26)
- Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity. (2011) (24)
- Narrowing the spectrum: the new frontier of precision antimicrobials (2017) (24)
- Structure-activity relationships of galabioside derivatives as inhibitors of E. coli and S. suis adhesins: nanomolar inhibitors of S. suis adhesins. (2005) (23)
- NMR studies of interactions between periplasmic chaperones from uropathogenic E. coli and pilicides that interfere with chaperone function and pilus assembly. (2005) (23)
- Symposium report on urothelial dysfunction: pathophysiology and novel therapies. (2006) (22)
- Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation (2016) (21)
- Stereoselective synthesis of optically active bicyclic beta-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteria. (2003) (21)
- Estrogen and Recurrent UTI: What Are the Facts? (2013) (21)
- Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation (2018) (21)
- The Detection of Bacteria and Matrix Proteins on Clinically Benign and Pathologic Implants (2019) (21)
- Dissection of Pilus Tip Assembly by the FimD Usher Monomer (2013) (20)
- Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women (2022) (20)
- The UbiI (VisC) Aerobic Ubiquinone Synthase Is Required for Expression of Type 1 Pili, Biofilm Formation, and Pathogenesis in Uropathogenic Escherichia coli (2016) (20)
- Functionalization of bicyclic 2-pyridones targeting pilus biogenesis in uropathogenic Escherichia coli (2007) (20)
- Role of intestinal surfactant-like particles as a potential reservoir of uropathogenic Escherichia coli. (2000) (20)
- Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli. (2002) (18)
- StrainGE: a toolkit to track and characterize low-abundance strains in complex microbial communities (2021) (18)
- Escherichia coli–Mediated Impairment of Ureteric Contractility Is Uropathogenic E. coli Specific (2012) (18)
- Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity. (2014) (17)
- The Structure of the PapD-PapGII Pilin Complex Reveals an Open and Flexible P5 Pocket (2012) (17)
- Deposition of Host Matrix Proteins on Breast Implant Surfaces Facilitates Staphylococcus Epidermidis Biofilm Formation: In Vitro Analysis. (2019) (17)
- Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence (2019) (17)
- Correction: Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex (2008) (17)
- X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI (1999) (17)
- A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of Chlamydia trachomatis (2014) (17)
- Synthesis and evaluation of dihydroimidazolo and dihydrooxazolo ring-fused 2-pyridones—targeting pilus biogenesis in uropathogenic bacteria (2008) (17)
- High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration (2019) (16)
- Advanced glycation end products facilitate bacterial adherence in urinary tract infection in diabetic mice. (2015) (16)
- (p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection (2019) (16)
- PapG adhesin from E. coli J96 recognizes the same saccharide epitope when present on whole bacteria and as isolated protein. (1996) (16)
- Evidence for donor strand complementation in the biogenesis of Haemophilus influenzae haemagglutinating pili (2000) (16)
- Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections (2021) (15)
- Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic mice. (2015) (15)
- Structural biology: Anthrax hijacks host receptor (2004) (14)
- Bacterial Spelunkers (2000) (14)
- Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design. (2018) (13)
- Fimbriae reprogram host gene expression – Divergent effects of P and type 1 fimbriae (2019) (13)
- Pilicide ec 240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli (2015) (13)
- Binding of peptides in solution by the Escherichia coli chaperone PapD as revealed using an inhibition ELISA and NMR spectroscopy. (1998) (12)
- Establishment and Characterization of Bacterial Infection of Breast Implants in a Murine Model. (2020) (12)
- Reaching the End of the Line (2020) (11)
- Efficient regioselective synthesis of enantiomerically pure 4-hydroxymethyl-Δ2-thiazoline (1998) (10)
- Differential Regulation of Escherichia coli fim Genes following Binding to Mannose Receptors (2018) (10)
- One size doesn't fit all: unraveling the diversity of factors and interactions that drive E. coli urovirulence. (2017) (9)
- Blueprinting the regulatory response of Escherichia coli to the urinary tract. (2005) (9)
- Synthetic polymer nanoparticles conjugated with FimH(A) from E. coli pili to emulate the bacterial mode of epithelial internalization. (2012) (8)
- LRP6 Holds the Key to the Entry of Anthrax Toxin (2006) (8)
- A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis. (2021) (8)
- Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in E. coli (2018) (8)
- Erratum: The biology and future prospects of antivirulence therapies (2009) (7)
- The unexplored relationship between urinary tract infections and the autonomic nervous system (2016) (7)
- What does it take to stick around? (2012) (7)
- Adaptation of Arginine Synthesis among Uropathogenic Branches of the Escherichia coli Phylogeny Reveals Adjustment to the Urinary Tract Habitat (2020) (7)
- Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections (2022) (7)
- Peptides inhibit complexation of the bacterial chaperone papd and reveal potential to block assembly of virulence associated pili (1995) (6)
- Uropathogenic Escherichia coli Virulence and Gene Regulation (2013) (5)
- Pili and Fimbriae of Gram-Negative Bacteria (2015) (5)
- Small-molecule inhibitors target Escherichia coli amyloid (5)
- RECENT ADVANCES IN THE MOLECULAR BASIS OF PATHOGEN RECOGNITION AND HOST RESPONSES IN THE URINARY TRACT (2002) (5)
- Transferred nuclear Overhauser effect spectroscopy study of a peptide from the PapG pilus subunit bound by the Escherichia coli PapD chaperone (1997) (5)
- Uropathogenic escherichia coli: interactions with bladder epithelium. (2001) (4)
- Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli (2018) (4)
- Stereoselective Synthesis of Optically Active β-Lactams, Potential Inhibitors of Pilus Assembly in Pathogenic Bacteria. (2000) (4)
- Innate defense evicts bacterial squatters (2002) (4)
- Biofilm and Urogenital Infections (2011) (3)
- Infectious disease and women's health (2008) (3)
- Small‐molecule inhibitors against type 1 pili selectively target uropathogenic E. coli in the gut and bladder (2017) (3)
- Antitoxins: therapy for stressed bacteria. (2011) (3)
- Chaos controlled: discovery of a powerful amyloid inhibitor. (2015) (3)
- Gut-bladder axis syndrome associated with recurrent UTIs in humans (2021) (3)
- Specificity mapping of bacterial lectins by inhibition of hemagglutination using deoxy and deoxyfluoro analogs of receptor-active saccharides. (1995) (3)
- Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections. (2016) (3)
- Bacterial Adherence in Pathogenicity (1989) (3)
- Cell biology: Bacteria thread the needle (2001) (3)
- Molecular escorts required to present bacterial adhesins to eukaryotic receptors (1994) (2)
- StrainGE: a toolkit to track and characterize low-abundance strains in complex microbial communities (2022) (2)
- 2019 ( p ) ppGpp and CodY promote Enterococcus faecalis virulence in a murine model of catheter-associated urinary tract infection (2019) (2)
- Catheterization of mice triggers resurgent urinary tract infection seeded by a bladder reservoir of Acinetobacter baumannii (2023) (2)
- Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome (2023) (2)
- Assembly of Adhesive Organelles on Gram-Negative Bacteria (2003) (2)
- Stereoselective synthesis of optically active bicyclic β-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteriaElectronic supplementary information (ESI) available: 13C NMR spectra of 7(a–g), 10–14, 16(a and d) and 17(a–b). See http://www.rsc.org/suppdata/ob/b2/b210551a/ (2003) (2)
- Isolation of the Pre-Assembled Gal α(1–4)Gal-Specific Pilus-Associated Adhesin from the Periplasm in Uropathogenic Escherichia Coli (1989) (2)
- Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics (2022) (2)
- The Chaperone-Usher Pathway of Pilus Fiber Biogenesis (2005) (2)
- Adhesive pili of the chaperone-usher family (2013) (2)
- Cover Picture: Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI (ChemMedChem 4/2016) (2016) (1)
- 7 Host-pathogen interactions: Structure and function of pili (2002) (1)
- , Scott of Urinary Tract Infection Group B Streptococcus in a Murine Model Immune Activation and Suppression (2011) (1)
- Enterococcus faecalis Infection-Associated Virulence Factors in AhrC and Eep Are Biofilm (2014) (1)
- FimH Inhibitors Treatment and Prevention of Urinary Tract Infection with Orally Active (2011) (1)
- Mechanisms of Bacterial Adhesion and Consequences of Attachment (2006) (1)
- Biogenesis of pili adhesins associated with urinary tract infectious Escherichiacoli (2004) (1)
- Characterization of Host-Pathogen-Device Interactions in Pseudomonas aeruginosa Infection of Breast Implants (2022) (1)
- FIBRINOGEN DEPOSITS ON URINARY CATHETERS IN A TIME‐DEPENDENT MATTER AND CO‐LOCALIZES WITH E. FAECALIS IN PATIENTS WITH POSITIVE E. FAECALIS URINE CULTURES: MP23‐19 (2017) (1)
- Dawn of the Postantibiotic Era Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the (2014) (0)
- Expression Effects of FimK on Type 1 Pilus Urinary Tract Infection and pneumoniae Klebsiella Community Pathway in Utilization of an Intracellular Bacterial (2014) (0)
- Washington University Record, April 14, 1994 (2014) (0)
- Structural and Functional Characterization of Outer Membrane Usher Activation in Uropathogenic E. coli (2017) (0)
- BINARY COMPLEX OF THE PAPG RECEPTOR-BINDING DOMAIN BOUND TO GBO4 RECEPTOR (2001) (0)
- F9 Pilus Adhesin FmlH Lectin Domain from E. coli UTI89 in Complex with Galactoside 2'-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-nitro-[1,1'-biphenyl]-3-carboxylic acid (2019) (0)
- UNIVERSITY OF WISCONSIN-LA CROSSE Graduate Studies EFFECTS OF THE ESCHERICHIA COLI SMALL REGULATORY RNAS OMRA AND OMRB ON GLOBAL TRANSCRIPTION FOLLOWING GROWTH IN HUMAN URINE (2018) (0)
- FimH adhesin receptor binding domain from uropathogenic E. coli (2005) (0)
- Crystal structure of the PapC usher bound to the chaperone-adhesin PapD-PapG (2018) (0)
- Urinary Tract Infections , their Frequency and Most Common Provocative Thing in the Region of Tetovo in the Period between 2012-2013 Healthcare (2014) (0)
- Narrowing the spectrum: the new frontier of precision antimicrobials (2017) (0)
- The Vital Role of ORWH (2009) (0)
- RoleofType1Pili andEffects ofPhaseVariation on LowerUrinary Tract Infections Produced byEscherichia coli (1985) (0)
- 1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli (2005) (0)
- Defining the roles of pyruvate oxidation, TCA cycle, and mannitol metabolism in methicillin resistance Staphylococcus aureus catheter-associated urinary tract infection (2022) (0)
- United States Patent Hultgren (2017) (0)
- FimH-dependent bacterial induction of Matrilysin in epithelial cells (1997) (0)
- Peptides recognized by the chaperone PapD from E. coli (1995) (0)
- Complete Genome Sequence of the Uropathogenic Methicillin-Resistant Staphylococcus aureus Strain MRSA-1369 (2022) (0)
- Antimicrobial susceptibility of bacteria in biofilm (2012) (0)
- Precision antimicrobial therapeutics: the path of least resistance? (2018) (0)
- Sugar Recognition and Bacterial Attachment (2005) (0)
- Crystal structure of the C-terminal domain of the PapC usher (2010) (0)
- Crystal structure of para-biphenyl-2-methyl-3', 5' di-methyl amide mannoside bound to FimH lectin domain (2016) (0)
- Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes (2019) (0)
- Table of Contents (1993) (0)
- Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia coli FimH Adhesin (2006) (0)
- F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with 8-hydroxyquinoline beta-galactoside (2018) (0)
- Crystal Structure of the Periplasmic Chaperone SfaE (2002) (0)
- Novel compounds to treat urinary tract infection [abstract] (2010) (0)
- Crystal structure of the PapE (N-terminal-deleted) pilus subunit bound to a peptide corresponding to the N-terminal extension of the PapK pilus subunit (residues 1-11) from uropathogenic E. coli (2002) (0)
- Peptides inhibit the complexation between the type 1 pilus adhesin FimH and the periplasmic chaperone FimC. (2004) (0)
- E. coli F9 pilus adhesin FmlH bound to the Thomsen-Friedenreich (TF) antigen (2016) (0)
- Structure of the curli transport lipoprotein CsgG in its membrane- bound conformation (2014) (0)
- THE FIMH ADHESIN OF TYPE 1 FIMBRIAE IS REQUIRED FOR ESCHERICHIA COLI TO GENERATE CYSTITIS IN A PRIMATE MODEL (1999) (0)
- Structure of the E. coli chaperone PapD in complex with the pilin domain of the PapGII adhesin (2010) (0)
- Efficient Regioselective Synthesis of Enantiomerically Pure 4-Hydroxymethyl-Δ2-thiazoline. (1998) (0)
- Structure of the P pilus usher (PapC) translocation pore (2008) (0)
- Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma (2019) (0)
- Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (F17A mutant) (2006) (0)
- 9 Biofilm and Urogenital Infections (2018) (0)
- Crystal structure of FimH A62S from E. coli UTI89 bound to FimG N-terminal extension (2017) (0)
- Correlative Light, Electron, and Ion Microscopy for the Study of Urinary Tract Infection Pathogenesis (2017) (0)
- Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections (2021) (0)
- Ushers and other doorkeepers: Response (1999) (0)
- Update on bioWlm infections in the urinary tract (2011) (0)
- Dynamic Sampling of Multiple Conformations in FimH Modulates Bacterial Adhesion (2016) (0)
- G‐CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity (2010) (0)
- Escherichia coli Uropathogenic in Mice Infected with on Recurrent Bacteriuria and Bacterial Effect of Trimethoprim-Sulfamethoxazole (2014) (0)
- CRYSTAL STRUCTURES OF SELF CAPPING PAPD CHAPERONE HOMODIMERS (1999) (0)
- Title Significance of the d-Serine-deaminase and d-Serinemetabolism of staphylococcus saprophyticus for virulence (2017) (0)
- Structure of the curli transport lipoprotein CsgG in a non-lipidated, pre-pore conformation (2014) (0)
- Characterizing the Structural Basis for USHER Activation (2016) (0)
- F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG) (2018) (0)
- MINIREVIEW Adhesin Presentation inBacteria Requires Molecular Chaperones andUshers (1992) (0)
- Functional role of the type 1 pilus rod structure in mediating host-pathogen 1 interactions 2 3 (2018) (0)
- CHAPTER 10 – Adhesive Pili of the Chaperone-Usher Family (2002) (0)
- F9 Pilus Adhesin FmlH Lectin Domain from E. coli UTI89 in Complex with Galactoside 5-nitro-2'-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-[1,1'-biphenyl]-3-carboxylic acid (2019) (0)
- Colonization of the Urinary Tract (2008) (0)
- PAPG ADHESIN RECEPTOR BINDING DOMAIN-UNBOUND FORM (2001) (0)
- High levels of antibiotic tolerance and persistence are induced by the commercial anti-microbial triclosan (2016) (0)
- Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (2006) (0)
- 1999 XIII International Biophysics Congress 19-24 September 1999 New Delhi Abstracts Suppl (2016) (0)
- Lectin domain of E. coli F9 pilus adhesin FmlH (2016) (0)
- coli Escherichia Responses by Uropathogenic Suppression of Bladder Epithelial Cytokine (2014) (0)
- Structure, Function, and Biogenesis of Escherichia coli P Pili (2020) (0)
- MP20-15 FIBRINOGEN RELEASE AND DEPOSITION ON URINARY CATHETERS PLACED DURING UROLOGIC PROCEDURES (2015) (0)
- What does it take to stick around?: Molecular insights into biofilm formation by uropathogenic Escherichia coli (2022) (0)
- Strain Tracking with Uncertainty Quantification (2023) (0)
- Escherichia coli Uropathogenic Pilicide ec 240 Disrupts Virulence Circuits in 2014 (2015) (0)
- Molecular Characterization of the Interaction Between HifB and HifA in the Biogenesis of H. influenzae Hemagglutinating Pili 867 (1998) (0)
- RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA (2018) (0)
- Structural basis for outer membrane usher activation to catalyze P pilus assembly in E. coli (2018) (0)
- F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with TF antigen (2018) (0)
- Structural and Functional Characterization of an F17‐Like CUP Adhesin from Uropathogenic E. coli Isolate UTI89 (2017) (0)
- X-Ray Structure of the Chaperone PapD in complex with the Pilus terminator subunit PapH at 2.3 Angstrom resolution (2006) (0)
- Structural and functional insights into the adaptor subunit function of PapF in pilus biogenesis (2008) (0)
- Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection (2017) (0)
- Structural and Functional Insights into Three Undercharacterized Fimbrial Adhesins (2016) (0)
- Salmonella enterica SafA pilin, head-to-tail swapped dimer of Ntd1 mutant (2006) (0)
- Urinary tract infections trigger synucleinopathy via the innate immune response (2023) (0)
- Urinary Tract Infections Body-Mediated Inflammation To Establish Enterococcus faecalis Overcomes Foreign (2014) (0)
- Electrophysiological Analysis of PapC Mutants Provides Insights into the Mechanism of Plug Displacement (2014) (0)
- Bacterial infection drives trained immunity through epigenetic remodeling of epithelial stem cells (2021) (0)
- Fimbriae and Pili (2002) (0)
- PapDchaperone capsanduncaps interactive surfaces ofnascently translocated pilus subunits (1991) (0)
- Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies (2020) (0)
- Salmonella enterica SafA pilin in complex with the SafB chaperone (Type II) (2006) (0)
- Urinary Tract Infections With Aerococcus Urinae in the South of The Netherlands (1998) (0)
- Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester. (2010) (0)
- E. coli P Pilus chaperone PapD in complex with a pilus biogenesis inhibitor, pilicide 2c (2006) (0)
- Contributory presentations/posters (1999) (0)
- Impairment of the biomechanical compliance of P pili: a novel means of inhibiting uropathogenic bacterial infections? (2012) (0)
- PAPD-PAPK CHAPERONE-PILUS SUBUNIT COMPLEX FROM E.COLI P PILUS (1999) (0)
- Structure–function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections (2023) (0)
- Escherichia coli Lipopolysaccharide and Type 1 Piliated Activation of Bladder Epithelial Cells by CD14- and Toll-Like Receptor-Dependent (2014) (0)
- Crystal Structure of the Lectin Domain From the F17-like Adhesin, UclD (2017) (0)
- Through a Lipopolysaccharide-Dependent Escherichia coli Cytokine Responses to Bacterial Invasion Augments Epithelial (2000) (0)
- Cryo-Em Structure of Type 1 Pilus (2018) (0)
- Treponema pallidum: doing a remarkable job with what it's got (1999) (0)
- SdrI in Virulence Tract Infection Reveals Roles for Ssp and Urinary Staphylococcus saprophyticus Characterization of a Novel Murine Model of (2014) (0)
- Crystal structure of the PapD chaperone (C-terminally 6x histidine-tagged) bound to the PapE pilus subunit (N-terminal-deleted) from uropathogenic E. coli (2002) (0)
- Crystal Structure of the Streptococcus pyogenes NAD+ glycohydrolase SPN in complex with IFS, the Immunity Factor for SPN (2011) (0)
- F9 Pilus Adhesin FmlH Lectin Domain from E. coli UTI89 in Complex with Galactoside N-[(2S,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[S-methyl-6-(trifluoromethyl)-[1,1'-biphenyl]-3'-yl]oxy}oxan-3-yl]acetamide (2019) (0)
- F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside (2018) (0)
- NMR studies of the interactions between pilicides and periplasmic chaperones from uropathogenic E. coli (2004) (0)
- Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope (2008) (0)
- during Acute and Chronic Urinary Tract Infection 2 (2011) (0)
- Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89 (2018) (0)
- Design, Synthesis and Biological Evaluation of Pilicides: Inhibitors of Pilus Assembly in Pathogenic Bacteria (2001) (0)
- Salmonella enterica SafA pilin in complex with the SafB chaperone (2006) (0)
- The commercial antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo (2018) (0)
- E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 2c (2010) (0)
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