Sergei Mirkin

Q: What Schools Are Affiliated With Sergei Mirkin

Sergei Mirkin is affiliated with the following schools: Tufts University, Moscow State University, University of Illinois Chicago

Sergei Mirkin's AcademicInfluence.com Rankings

Sergei Mirkin

Biology

#6285

World Rank

#8963

Historical Rank

Genetics

#1098

World Rank

#1197

Historical Rank

biology Degrees

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Biology

Why Is Sergei Mirkin Influential?

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According to Wikipedia, Sergei Mirkin is a Russian-American biologist who studies genome instability mediated by repetitive DNA during DNA replication and transcription. He is a professor of Genetics and Molecular Biology and holds the White Family Chair in Biology at Tufts University.

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Sergei Mirkin's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Expandable DNA repeats and human disease (2007) (852)
Triplex DNA structures. (1995) (641)
Replication Fork Stalling at Natural Impediments (2007) (482)
Human mutation rate associated with DNA replication timing (2009) (396)
Trinucleotide repeats affect DNA replication in vivo (1997) (339)
DNA H form requires a homopurine–homopyrimidine mirror repeat (1987) (317)
DNA structures, repeat expansions and human hereditary disorders. (2006) (239)
Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins (2008) (238)
H-DNA and related structures. (1994) (218)
Replication Stalling at Friedreich's Ataxia (GAA)n Repeats In Vivo (2004) (193)
Replication and Expansion of Trinucleotide Repeats in Yeast (2003) (162)
Mechanisms of Transcription-Replication Collisions in Bacteria (2005) (161)
Structures of homopurine-homopyrimidine tract in superhelical DNA. (1986) (144)
Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. (2009) (132)
Characteristic enrichment of DNA repeats in different genomes. (1997) (128)
Mechanisms and implications of transcription blockage by guanine-rich DNA sequences (2010) (127)
Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility (2009) (123)
Chemical probing of homopurine-homopyrimidine mirror repeats in supercoiled DNA (1988) (122)
Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair (2013) (120)
Transcriptionally driven cruciform formation in vivo. (1992) (114)
A stable complex between homopyrimidine oligomers and the homologous regions of duplex DNAs. (1988) (110)
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability (2020) (107)
Discovery of alternative DNA structures: a heroic decade (1979-1989). (2008) (103)
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair (2008) (101)
The balancing act of DNA repeat expansions. (2013) (98)
A pH-dependent structural transition in the homopurine-homopyrimidine tract in superhelical DNA. (1985) (97)
Large-scale effects of transcriptional DNA supercoiling in vivo. (1999) (92)
DNA sequences that interfere with transcription: implications for genome function and stability. (2013) (90)
Transcription through a simple DNA repeat blocks replication elongation (1998) (88)
Intramolecular DNA triplexes: unusual sequence requirements and influence on DNA polymerization. (1992) (84)
Overcoming natural replication barriers: differential helicase requirements (2011) (80)
Formation of (dA-dT)n cruciforms in Escherichia coli cells under different environmental conditions (1991) (73)
Suicidal nucleotide sequences for DNA polymerization. (1993) (72)
The energetics of the B-Z transition in DNA. (1987) (71)
Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability (2017) (68)
Genome rearrangements caused by interstitial telomeric sequences in yeast (2013) (64)
Role of DNA polymerases in repeat-mediated genome instability. (2012) (63)
Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. (2012) (63)
Mechanisms of triplex-caused polymerization arrest. (1997) (62)
The role of break-induced replication in large-scale expansions of (CAG)n•(CTG)n repeats (2016) (61)
Transcription regulatory elements are punctuation marks for DNA replication. (2006) (59)
Formation of intramolecular triplex in homopurine-homopyrimidine mirror repeats with point substitutions. (1990) (57)
Transcription blockage by homopurine DNA sequences: role of sequence composition and single-strand breaks (2012) (55)
DNA Topology: Fundamentals (2001) (55)
At the Beginning of the End and in the Middle of the Beginning: Structure and Maintenance of Telomeric DNA Repeats and Interstitial Telomeric Sequences (2019) (53)
H-DNA and Z-DNA in the mouse c-Ki-ras promoter. (1991) (51)
An unusual DMA structure detected in a telomeric sequence under superhelical stress and at low pH (1989) (51)
A structural transition in d(AT)n.d(AT)n inserts within superhelical DNA. (1985) (50)
Positioned to expand (2002) (47)
Checkpoint responses to unusual structures formed by DNA repeats (2009) (46)
Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast (2011) (46)
Effects of Friedreich's ataxia (GAA)n·(TTC)n repeats on RNA synthesis and stability. (2007) (45)
RNA–DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication (2018) (44)
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways (2019) (41)
Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells (2012) (41)
Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae (2011) (41)
Trapping DNA polymerases using triplex-forming oligodeoxyribonucleotides. (1994) (38)
Chemical probing of the homopurine·homopyrimidine tract in supercoiled DNA at single‐nucleotide resolution (1988) (37)
Expansion of the (CTG)(n) repeat in the 5'-UTR of a reporter gene impedes translation. (2000) (35)
Structure of (dG)n.(dC)n under superhelical stress and acid pH. (1987) (34)
Precarious maintenance of simple DNA repeats in eukaryotes (2017) (34)
Quantitative Analysis of the Rates for Repeat-Mediated Genome Instability in a Yeast Experimental System. (2018) (31)
Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair (2017) (31)
To switch or not to switch: at the origin of repeat expansion disease. (2014) (30)
The hidden side of unstable DNA repeats: Mutagenesis at a distance. (2015) (30)
Mechanisms of genetic instability caused by (CGG)n repeats in an experimental mammalian system (2018) (29)
Expansion of Trinucleotide Repeats (2001) (25)
Toward a unified theory for repeat expansions (2005) (24)
Transcription blockage by stable H-DNA analogs in vitro (2015) (24)
Mrc1 and Tof1 prevent fragility and instability at long CAG repeats by their fork stabilizing function (2018) (21)
The ionic strength dependence of the cooperativity factor for DNA melting. (1987) (21)
Genetic Control of Genomic Alterations Induced in Yeast by Interstitial Telomeric Sequences (2018) (20)
Energetics of the B-H transition in supercoiled DNA carrying d(CT)x.d(AG)x and d(C)n.d(G)n inserts. (1989) (20)
Analysis of triplet repeat replication by two-dimensional gel electrophoresis. (2004) (20)
Large-scale contractions of Friedreich’s ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability (2020) (20)
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability. (2020) (20)
The absence of cruciform structures from pAO3 plasmid DNA in vivo. (1984) (20)
Transcriptional activity of the homopurine-homopyrimidine repeat of the c-Ki-ras promoter is independent of its H-forming potential. (1994) (19)
Expansion of Interstitial Telomeric Sequences in Yeast. (2015) (18)
Cis- and Trans-Modifiers of Repeat Expansions: Blending Model Systems with Human Genetics. (2018) (18)
Schizosaccharomyces pombe Ddb1 Is functionally Linked to the Replication Checkpoint Pathway* (2003) (17)
A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich's Ataxia. (2017) (17)
Coupling transcriptional state to large-scale repeat expansions in yeast. (2014) (15)
DNA replication: Driving past four-stranded snags (2013) (14)
DNA Supercoiling and transcription in Escherichia coli: Influence of RNA polymerase mutations (2004) (11)
A new trick for an old dog: TraY binding to a homopurine-homopyrimidine run attenuates DNA replication. (2001) (11)
Replication-independent instability of Friedreich’s ataxia GAA repeats during chronological aging (2021) (10)
Structure and Biology of H DNA (1999) (10)
[Influence of DNA superhelicity on the major genetic processes in prokaryotes]. (1980) (6)
Trapping DNA polymerases using triplex-forming (1994) (5)
DNA replication and transcription in a temperature-sensitive mutant of E. coli with a defective DNA gyrase B subunit (2004) (5)
Getting to the core of repeat expansions by cell reprogramming. (2010) (4)
Rad9-mediated checkpoint activation is responsible for elevated expansions of GAA repeats in CST-deficient yeast. (2021) (4)
CHAPTER 40 – Replication of Expandable DNA Repeats (2006) (3)
Triple-Helical Nucleic Acids By Valery N. Soyfer (George Mason University) and Vladimir N. Potaman (Texas A&M University). Springer: New York. 1995. xiv + 360 pp. $79.00. ISBN 0-387-94495-8. (1997) (2)
[Interactions of subunits of DNA gyrase]. (1982) (2)
130 Transcription blockage by single-strand breaks in various sequences and the general model for transcription blockage by R-loop formation (2013) (2)
Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability (2017) (2)
Native supercoiling of DNA: The effects of DNA gyrase and ω protein in E. coli (2004) (2)
A Tribute to Evgenii V. Ananiev, 1947–2008 (2008) (2)
Changed properties of the A subunit in DNA gyrase with a B subunit mutation (2004) (1)
S1-END-seq reveals DNA secondary structures in human cells. (2022) (1)
[Effect of DNA supercoiling on transcription performed by normal and mutant Escherichia coli RNA-polymerases]. (1979) (1)
Partners in crime: Tbf1 and Vid22 promote expansions of long human telomeric repeats at an interstitial chromosome position in yeast (2022) (1)
Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements (2023) (1)
Putting the Brakes on Huntington Disease in a Mouse Experimental Model (2015) (1)
Experimental System to Study Instability of (CGG)n Repeats in Cultured Mammalian Cells. (2019) (1)
Large-scale expansions and replication stalling of Friedreich’s ataxia GAA repeats in an experimental mammalian system (2022) (1)
131 Using whole-genome sequencing to search for trans-modifiers of repeat expansions (2013) (1)
Large-scale expansions of Friedreich’s ataxia GAA•TTC repeats in human cells are prevented by LNA-DNA oligonucleotides and PNA oligomers (2022) (1)
Replication dependent and independent mechanisms of GAA repeat instability. (2022) (0)
Fleeing Russian researchers seek Western support (2022) (0)
[Transfer of "artificial transposons" constructed on the basis of insertion element IS1]. (1987) (0)
Institute ofMolecular Genetics, USSRAcademyofSciences, Moscow123182 andlInstitute of Limnoligy, Siberian Branch oftheUSSRAcademyofSciences, Irkutsk, USSR (1989) (0)
A Renaissance Man: In Memoriam of Jon Widom (1955–2011) (2011) (0)
Expansion of Interstitial T elomeric Sequences in Yeast Graphical (0)
Characteristics and possible mechanisms of formation of microinversions distinguishing human and chimpanzee genomes (2022) (0)
INSTABILITY OF INTERSTITIAL TELOMERIC SEQUENCES (2015) (0)
INSERTION OF (DA-DT)N BLOCKS INTO REGULATORY REGION OF SACCHAROMYCES CEREVISIAE PHO5 GENE IMPAIRS ITS EXPRESSION (1990) (0)
Faculty Opinions recommendation of Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling. (2021) (0)
B—Z transition in DNA with an arbitrary base-pair sequence (1987) (0)
Characteristics of Repeat Expansions Expansions of simple DNA repeats account for more than two dozen hereditary disorders in humans (2005) (0)
[Temperature-sensitive mutant Escherichia coli for the B-subunit of DNA-gyrase. The effect on replication and transcription]. (1983) (0)
Characteristics and possible mechanisms of formation of microinversions distinguishing human and chimpanzee genomes (2022) (0)
The ionic strength dependence of the cooperativity factor in DNA melting (1986) (0)
[Primary structure of two natural IS1-flanking transposons Tn9* and Tn9' coding for stability to chloramphenicol]. (1991) (0)
Anand, NAR 2011.full (2015) (0)
Expansion of Interstitial T elomeric Sequences in Yeast Graphical (0)
[Insertion of (dA-dT)n sequences into the regulatory region of the pho5 gene inhibits its expression]. (1990) (0)
Faculty Opinions recommendation of R-loop formation during S phase is restricted by PrimPol-mediated repriming. (2018) (0)
Mechanisms of genetic instability caused by (CGG)n repeats in an experimental mammalian system (2018) (0)
Formation ofintramolecular triplex inhomopurine- homopyrimidine mirror repeats withpoint substitutions (1990) (0)
Faculty Opinions recommendation of Repeat expansions confer WRN dependence in microsatellite-unstable cancers. (2020) (0)
Replication of simple DNA repeats Review Article (2001) (0)
Suicidal nucleotide sequencesforDNA polymerization (1993) (0)
Coupling Transcriptional S tate to Large-Scale Repeat Expansions in Yeast Graphical (2014) (0)
Native supercoiling of DNA: the effects of DNA gyrase and omega protein in E. coli. (1984) (0)
67 REPLICATION OF DNA PALINDROMES AND CHROMOSOMAL INSTABILITY. (2007) (0)
[Effect of superhelical DNA on the transcription of cloned genes of the T4 phage]. (1986) (0)
Coupling Transcriptional S tate to Large-Scale Repeat Expansions in Yeast Graphical (2014) (0)
[Nature of the plasmids determining the unstable inheritance of transposon Tn9 in Escherichia coli K-12]. (1983) (0)
[Development of bacteriophage Mu in E. coli gyrBts mutant strain]. (1985) (0)
Linking Dynamic DNA Secondary Structures to Genome Instability (2022) (0)

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What Schools Are Affiliated With Sergei Mirkin?

Sergei Mirkin is affiliated with the following schools: