Sergio Fazio
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Physics
Sergio Fazio's Degrees
- PhD Physics University of California, Berkeley
- Masters Physics University of California, Berkeley
- Bachelors Physics University of California, Berkeley
Why Is Sergio Fazio Influential?
(Suggest an Edit or Addition)Sergio Fazio's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel (2017) (1817)
- Current perspectives on statins. (2000) (1213)
- Low-density lipoproteins cause atherosclerotic cardiovascular disease (2018) (936)
- Premature coronary-artery atherosclerosis in systemic lupus erythematosus. (2003) (886)
- AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION OF CARDIOVASCULAR DISEASE. (2017) (800)
- Lack of macrophage fatty-acid–binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis (2001) (657)
- Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2 (2007) (636)
- Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. (1999) (558)
- Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel (2020) (541)
- Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes. (2016) (512)
- Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation (1995) (471)
- Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis (2009) (461)
- HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. (2011) (441)
- Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk: Insights From the FOURIER Trial (2018) (378)
- B-Lymphocyte Deficiency Increases Atherosclerosis in LDL Receptor–Null Mice (2002) (323)
- Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice (2002) (301)
- Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages. (1997) (293)
- Macrophages, inflammation, and atherosclerosis (2003) (278)
- NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis. (2018) (276)
- Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges (2012) (272)
- Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. (2001) (250)
- The relationship between dose of vitamin E and suppression of oxidative stress in humans. (2007) (242)
- Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo. (1999) (239)
- Reduced Macrophage Apoptosis Is Associated With Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice (2004) (227)
- Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1. (2000) (226)
- Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans. (1994) (207)
- Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. (2001) (199)
- Inactivation of Macrophage Scavenger Receptor Class B Type I Promotes Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice (2003) (197)
- Metabolic syndrome and the risk of cardiovascular disease in older adults. (2006) (196)
- Conditional Knockout of Macrophage PPARγ Increases Atherosclerosis in C57BL/6 and Low-Density Lipoprotein Receptor–Deficient Mice (2005) (190)
- The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk. (2018) (183)
- Combined Adipocyte-Macrophage Fatty Acid–Binding Protein Deficiency Improves Metabolism, Atherosclerosis, and Survival in Apolipoprotein E–Deficient Mice (2004) (182)
- Serum Proprotein Convertase Subtilisin/Kexin Type 9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation (2013) (181)
- Overexpression of Human Apolipoprotein A-I Preserves Cognitive Function and Attenuates Neuroinflammation and Cerebral Amyloid Angiopathy in a Mouse Model of Alzheimer Disease* (2010) (179)
- Adipocyte Fatty Acid–Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation in Severe Hypercholesterolemia (2002) (172)
- Dysfunctional high-density lipoprotein in patients on chronic hemodialysis. (2012) (169)
- Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A (2000) (163)
- Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis (2002) (161)
- The severe hypercholesterolemia phenotype: clinical diagnosis, management, and emerging therapies. (2014) (155)
- Macrophage Lipoprotein Lipase Promotes Foam Cell Formation and Atherosclerosis in Low Density Lipoprotein Receptor-deficient Mice* (2000) (150)
- Deletion of Macrophage LDL Receptor–Related Protein Increases Atherogenesis in the Mouse (2007) (145)
- PCSK9: From Basic Science Discoveries to Clinical Trials (2018) (141)
- Purine-rich foods, protein intake, and the prevalence of hyperuricemia: the Shanghai Men's Health Study. (2012) (139)
- Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture. (1994) (137)
- Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation (2010) (135)
- Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia. (1994) (131)
- Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis. (2002) (130)
- Mouse models of hyperlipidemia and atherosclerosis. (2001) (130)
- Local effects of human PCSK9 on the atherosclerotic lesion (2016) (129)
- The Evolving Future of PCSK9 Inhibitors. (2018) (126)
- Cyclooxygenase-2 and inflammation in atherosclerosis. (2004) (126)
- Are statins diabetogenic? (2011) (122)
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. (2006) (121)
- Mutations in the ANGPTL3 gene and familial combined hypolipidemia: a clinical and biochemical characterization. (2012) (120)
- Quantitative and Qualitative Differences in Proatherogenic NKT Cells in Apolipoprotein E–Deficient Mice (2004) (119)
- Class A scavenger receptors, macrophages, and atherosclerosis (2001) (118)
- Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. (2010) (116)
- Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor–Dependent and –Independent Mechanisms (2014) (115)
- The role of fibrates in managing hyperlipidemia: Mechanisms of action and clinical efficacy (2004) (113)
- Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation. (1999) (110)
- Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. (2005) (109)
- Self-association of human PCSK9 correlates with its LDLR-degrading activity. (2008) (108)
- Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering. (2016) (104)
- Intra-individual Variation of Plasma Adipokine Levels and Utility of Single Measurement of These Biomarkers in Population-Based Studies (2007) (104)
- From Lipids to Inflammation: New Approaches to Reducing Atherosclerotic Risk. (2016) (104)
- Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor. (1998) (101)
- Macrophage Polarization by Angiotensin II-Type 1 Receptor Aggravates Renal Injury-Acceleration of Atherosclerosis (2011) (100)
- Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia. (2008) (97)
- Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. (2008) (96)
- Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. (2008) (96)
- PCSK9 Association With Lipoprotein(a). (2016) (96)
- A practical approach to risk assessment to prevent coronary artery disease and its complications. (2003) (95)
- Characterization of a new form of inherited hypercholesterolemia: familial recessive hypercholesterolemia. (1999) (92)
- A Direct Role for the Macrophage Low Density Lipoprotein Receptor in Atherosclerotic Lesion Formation* (1999) (91)
- AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION OF CARDIOVASCULAR DISEASE - EXECUTIVE SUMMARYComplete Appendix to Guidelines available at http://journals.aace.com. (2017) (89)
- Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity. (2011) (89)
- Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis[S] (2015) (87)
- Retention of Low-Density Lipoprotein in Atherosclerotic Lesions of the Mouse: Evidence for a Role of Lipoprotein Lipase (2007) (86)
- Loss of Plasma Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) After Lipoprotein Apheresis (2013) (85)
- The functional characteristics of a human apolipoprotein E variant (cysteine at residue 142) may explain its association with dominant expression of type III hyperlipoproteinemia. (1992) (85)
- Smoking, sex, risk factors and abdominal aortic aneurysms: a prospective study of 18 782 persons aged above 65 years in the Southern Community Cohort Study (2015) (85)
- Nonpharmacologic treatment of dyslipidemia. (2009) (78)
- Macrophage Expression of Peroxisome Proliferator–Activated Receptor-&agr; Reduces Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice (2007) (77)
- Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus. (2006) (77)
- Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner. (2011) (76)
- Novel Domain Interaction Regulates Secretion of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Protein* (2011) (75)
- On the function and homeostasis of PCSK9: reciprocal interaction with LDLR and additional lipid effects. (2015) (74)
- Increased residual cardiovascular risk in patients with diabetes and high versus normal triglycerides despite statin‐controlled LDL cholesterol (2018) (74)
- Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E. (1993) (73)
- Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Management of Dyslipidemia and Prevention of Cardiovascular Disease Algorithm - 2020 Executive Summary. (2020) (71)
- Is Isolated Low High-Density Lipoprotein Cholesterol a Cardiovascular Disease Risk Factor?: New Insights From the Framingham Offspring Study (2016) (71)
- Low-Density Lipoprotein Receptor–Related Protein 1 Prevents Early Atherosclerosis by Limiting Lesional Apoptosis and Inflammatory Ly-6Chigh Monocytosis: Evidence That the Effects Are Not Apolipoprotein E Dependent (2011) (70)
- Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms. (2016) (69)
- Determination of the lower threshold of apolipoprotein E resulting in remnant lipoprotein clearance. (1999) (68)
- A Recycling Pathway for Resecretion of Internalized Apolipoprotein E in Liver Cells* (2001) (68)
- Reduced ABCA1-Mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E–Deficient Mice Lacking Macrophage-Derived ACAT1 (2005) (67)
- Factors Associated With the Prevalence of Hypertension in the Southeastern United States: Insights From 69 211 Blacks and Whites in the Southern Community Cohort Study (2014) (66)
- Increased Cardiovascular Risk in Hypertriglyceridemic Patients With Statin-Controlled LDL Cholesterol (2018) (66)
- Atherosclerosis in chronic kidney disease: the role of macrophages (2011) (65)
- Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages (2018) (64)
- Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice. (2011) (61)
- Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies. (1999) (60)
- ACAT1 Deficiency Disrupts Cholesterol Efflux and Alters Cellular Morphology in Macrophages (2004) (59)
- Dysfunctional high-density lipoproteins in children with chronic kidney disease. (2015) (58)
- Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice. (2006) (58)
- Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice DOI 10.1194/jlr.M200108-JLR200 (2002) (58)
- Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease (2017) (57)
- The PCSK9 revolution: Current status, controversies, and future directions. (2020) (57)
- Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice[S] (2014) (56)
- Recycling of Apolipoprotein E in Mouse Liver* (1999) (56)
- PCSK9 and Atherosclerosis - Lipids and Beyond (2017) (54)
- Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice. (2008) (52)
- A Pathway-Dependent on ApoE, ApoAI, and ABCA1 Determines Formation of Buoyant High-Density Lipoprotein by Macrophage Foam Cells (2007) (52)
- Prevalence and determinants of hyperuricemia in middle-aged, urban Chinese men. (2010) (52)
- Angiotensin II Amplifies Macrophage-Driven Atherosclerosis (2004) (51)
- A Systematic Review of PCSK9 Inhibitors Alirocumab and Evolocumab. (2016) (51)
- Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-&ggr;–Regulated Genes (2011) (51)
- Increased Cholesterol Efflux in Apolipoprotein AI (ApoAI)–Producing Macrophages as a Mechanism for Reduced Atherosclerosis in ApoAI(−/−) Mice (2001) (51)
- Relationship of lipoprotein(a) molar concentrations and mass according to lipoprotein(a) thresholds and apolipoprotein(a) isoform size. (2018) (50)
- Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E(Arg 112,Cys142). (1994) (50)
- Cyclooxygenase-2 and atherosclerosis (2002) (50)
- The inflamed plaque: cytokine production and cellular cholesterol balance in the vessel wall. (2001) (48)
- The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes (2003) (48)
- Lifestyle determinants of C-reactive protein in middle-aged, urban Chinese men. (2012) (47)
- Re-emergence of fibrates in the management of dyslipidemia and cardiovascular risk (2000) (47)
- Lipoprotein Subclasses Determined by Nuclear Magnetic Resonance Spectroscopy and Coronary Atherosclerosis in Patients with Rheumatoid Arthritis (2010) (46)
- Retrovirus-mediated Expression of Apolipoprotein A-I in the Macrophage Protects against Atherosclerosis in Vivo * (2001) (46)
- The cell biology and physiologic relevance of ApoE recycling. (2000) (45)
- Relationship Between Low‐Density Lipoprotein Cholesterol and Lipoprotein(a) Lowering in Response to PCSK9 Inhibition With Evolocumab (2019) (44)
- Synthesis and secretion of apolipoprotein E occur independently of synthesis and secretion of apolipoprotein B-containing lipoproteins in HepG2 cells. (1992) (43)
- Free fatty acids are associated with metabolic syndrome and insulin resistance but not inflammation in systemic lupus erythematosus (2013) (43)
- Residual Cardiovascular Risk in Chronic Kidney Disease: Role of High-density Lipoprotein. (2015) (42)
- Application of PCSK9 Inhibitors in Practice: Part 2 The Patient Experience (2019) (42)
- Rapid quantification of murine ABC mRNAs by real time reverse transcriptase-polymerase chain reaction Published, JLR Papers in Press, September 1, 2002. DOI 10.1194/jlr.D200020-JLR200 (2002) (41)
- PMP22 Is Critical for Actin-Mediated Cellular Functions and for Establishing Lipid Rafts (2014) (41)
- Failure of ACAT inhibition to retard atherosclerosis. (2006) (41)
- DNA repair synthesis and DNA fragmentation in primary cultures of human and rat hepatocytes exposed to cyproterone acetate. (1995) (40)
- The enhanced association of apolipoprotein E with apolipoprotein B-containing lipoproteins in serum-stimulated hepatocytes occurs intracellularly. (1995) (40)
- Quantum dot mediated imaging of atherosclerosis (2009) (40)
- Increased Cerebral Cortical Lipid Peroxidation and Abnormal Phospholipids in Aged Homozygous apoE-Deficient C57BL/6J Mice (1999) (39)
- The recycling of apolipoprotein E in macrophages: influence of HDL and apolipoprotein A-I. (2005) (38)
- Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500101-JLR200 (2005) (38)
- Cyclooxygenase-1 Deficiency in Bone Marrow Cells Increases Early Atherosclerosis in Apolipoprotein E– and Low-Density Lipoprotein Receptor–Null Mice (2005) (37)
- Renal Dysfunction Potentiates Foam Cell Formation by Repressing ABCA1 (2009) (37)
- Obesity and altered glucose metabolism impact HDL composition in CETP transgenic mice: a role for ovarian hormones[S] (2012) (37)
- Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-&agr; Inhibition (2016) (37)
- Discordant response of low-density lipoprotein cholesterol and lipoprotein(a) levels to monoclonal antibodies targeting proprotein convertase subtilisin/kexin type 9. (2017) (36)
- Application of PCSK9 Inhibitors in Practice: Challenges and Opportunities (2017) (36)
- Severely altered cholesterol homeostasis in macrophages lacking apoE and SR-BI Published, JLR Papers in Press, February 13, 2007. (2007) (36)
- Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High‐Density Lipoprotein–Enriched Serum in Rheumatoid Arthritis (2016) (36)
- Macrophage Apolipoprotein E Reduces Atherosclerosis and Prevents Premature Death in Apolipoprotein E and Scavenger Receptor–Class BI Double-Knockout Mice (2006) (36)
- Long-term safety and efficacy of triple combination ezetimibe/simvastatin plus extended-release niacin in patients with hyperlipidemia. (2010) (36)
- Liver enzymes, type 2 diabetes, and metabolic syndrome in middle-aged, urban Chinese men. (2011) (35)
- Inflammatory mechanisms affecting the lipid profile in patients with systemic lupus erythematosus. (2007) (35)
- Hepatocyte-derived ApoE Is More Effective than Non-hepatocyte-derived ApoE in Remnant Lipoprotein Clearance* (2003) (35)
- Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques. (2007) (34)
- Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction. (2006) (33)
- Diagnosing Resistance to a Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor (2017) (33)
- A form of familial hypobetalipoproteinaemia not due to a mutation in the apolipoprotein B gene (1991) (33)
- Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant. (1994) (32)
- ApoE-mediated cholesterol efflux from macrophages: separation of autocrine and paracrine effects. (2005) (31)
- Accumulation of human apolipoprotein-E in rat plasma after in vivo intramuscular injection of naked DNA. (1994) (31)
- Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice (2016) (31)
- Plasma lipid levels and colorectal adenoma risk (2015) (31)
- Impaired Secretion of Apolipoprotein E2 from Macrophages* (2007) (31)
- Lipoprotein subclasses and particle size determined by nuclear magnetic resonance spectroscopy in systemic lupus erythematosus (2008) (31)
- Leukocyte low density lipoprotein receptor (LDL-R) does not contribute to LDL clearance in vivo: bone marrow transplantation studies in the mouse. (1997) (30)
- Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500181-JLR200 (2005) (30)
- Insights into Atherosclerosis Using Nanotechnology (2010) (30)
- Targeting PCSK9 for Therapeutic Gains (2015) (30)
- Combined Vitamin C and Vitamin E Deficiency Worsens Early Atherosclerosis in Apolipoprotein E–Deficient Mice (2010) (30)
- Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: a role for combination fibrate therapy. (2008) (30)
- Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL[S] (2015) (29)
- Macrophage IKK&agr; Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis (2016) (29)
- Isoform-Specific Effects of Apolipoprotein E on Atherogenesis: Gene Transduction Studies in Mice (2001) (28)
- Characterization of three mutations of the low density lipoprotein receptor gene in Italian patients with familial hypercholesterolemia. (1991) (28)
- Macrophage apolipoprotein A-I expression protects against atherosclerosis in ApoE-deficient mice and up-regulates ABC transporters. (2003) (27)
- Association of soy food intake with risk and biomarkers of coronary heart disease in Chinese men. (2014) (27)
- Preventive Cardiology as a Subspecialty of Cardiovascular Medicine: JACC Council Perspectives. (2019) (27)
- Risk of cardiovascular events in patients with hypertriglyceridaemia: A review of real‐world evidence (2019) (27)
- Effect of Extended-Release Niacin on New-Onset Diabetes Among Hyperlipidemic Patients Treated With Ezetimibe/Simvastatin in a Randomized Controlled Trial (2012) (27)
- Proatherogenic role for NK cells revealed. (2004) (27)
- Mechanism of Down-regulation of RNA Polymerase III-transcribed Non-coding RNA Genes in Macrophages by Leishmania* (2010) (27)
- Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese men. (2009) (26)
- The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment: evidence for multiple redundant pathways. (2004) (26)
- Threshold Effects of Circulating Angiopoietin‐Like 3 Levels on Plasma Lipoproteins (2017) (26)
- Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype. (2015) (26)
- High-density lipoprotein therapeutics and cardiovascular prevention. (2010) (26)
- Correlates of High Serum C-Reactive Protein Levels in a Socioeconomically Disadvantaged Population (2008) (25)
- ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages. (2006) (25)
- PCSK9 inhibition to reduce cardiovascular disease risk: recent findings from the biology of PCSK9 (2015) (25)
- A prospective study of statin use and mortality among 67,385 blacks and whites in the Southeastern United States (2013) (24)
- Cyclooxygenase products and atherosclerosis. (2008) (24)
- Evidence of metabolic syndrome in lean children with premature pubarche at diagnosis. (2008) (24)
- Free fatty acids are associated with insulin resistance but not coronary artery atherosclerosis in rheumatoid arthritis. (2011) (24)
- Consuming a balanced high fat diet for 16 weeks improves body composition, inflammation and vascular function parameters in obese premenopausal women. (2014) (24)
- Faculty Opinions recommendation of Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia. (2020) (23)
- Preferential association of apolipoprotein E Leiden with very low density lipoproteins of human plasma. (1993) (23)
- Selective macrophage ascorbate deficiency suppresses early atherosclerosis. (2011) (23)
- Oral retinoids and plasma lipids (2013) (22)
- A neutral lipid-enriched diet improves myelination and alleviates peripheral nerve pathology in neuropathic mice (2019) (22)
- Evaluation of macrophage-specific promoters using lentiviral delivery in mice (2011) (22)
- Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts. (2015) (22)
- Murine bone marrow transplantation as a novel approach to studying the role of macrophages in lipoprotein metabolism and atherogenesis. (1996) (21)
- Targeting cardiovascular risk in patients with diabetes: management of dyslipidemia (2008) (21)
- Lentiviral Transduction of ApoAI Into Hematopoietic Progenitor Cells and Macrophages: Applications to Cell Therapy of Atherosclerosis (2008) (21)
- Role of PAI-1 in hepatic steatosis and dyslipidemia (2021) (20)
- Long‐term efficacy and safety of ezetimibe/simvastatin coadministered with extended‐release niacin in hyperlipidaemic patients with diabetes or metabolic syndrome (2010) (19)
- Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low‐density lipoprotein receptor‐deficient mice (2021) (19)
- PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux (2019) (19)
- The Role of the Clinical Pharmacist in a Preventive Cardiology Practice (2019) (18)
- Chylomicronemia syndrome: Familial or not? (2020) (17)
- Pravastatin in heterozygous familial hypercholesterolemia: low-density lipoprotein (LDL) cholesterol-lowering effect and LDL receptor activity on skin fibroblastS. (1991) (17)
- CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet (2018) (17)
- HDL Particle Size and Functional Heterogeneity. (2016) (16)
- ACAT inhibition: bad for macrophages, good for smooth muscle cells? (2005) (16)
- Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression (2002) (16)
- Coronary Microvascular Dysfunction by Myocardial Contrast Echocardiography in Nonelderly Patients Referred for Computed Tomographic Coronary Angiography. (2019) (16)
- Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells Published, JLR Papers in Press, March 13, 2006. (2006) (16)
- Effects of 12 weeks of treatment with intravenously administered bococizumab, a humanized monoclonal antibody blocking proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects on high‐dose statin (2018) (15)
- Lipoprotein Apheresis Acutely Reverses Coronary Microvascular Dysfunction in Patients With Severe Hypercholesterolemia. (2019) (15)
- Uric acid correlates to oxidation and inflammation in opposite directions in women (2015) (15)
- Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis. (2016) (15)
- Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism (2018) (15)
- Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice. (2005) (14)
- Angiotensin-Induced Abdominal Aortic Aneurysms in Hypercholesterolemic Mice: Role of Serum Cholesterol and Temporal Effects of Exposure (2014) (14)
- Elevated high-density lipoprotein (HDL) levels due to hepatic lipase mutations do not reduce cardiovascular disease risk: another strike against the HDL dogma. (2009) (14)
- Impact of PCSK9 inhibitors on plasma lipoprotein(a) concentrations with or without a background of niacin therapy. (2019) (14)
- Unique pathway for cholesterol uptake in fat cells. (2004) (13)
- Apolipoprotein AI as therapy for atherosclerosis: does the future of preventive cardiology include weekly injections of the HDL protein? (2003) (13)
- High-Density Lipoprotein Carries Markers That Track With Recovery From Stroke (2020) (13)
- Sorting out the complexities of reverse cholesterol transport: CETP polymorphisms, HDL, and coronary disease. (2006) (13)
- Reduced ABCA 1-Mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E – Deficient Mice Lacking Macrophage-Derived ACAT 1 (2005) (13)
- Quantitative Estimates of the Variability of In Vivo Sonographic Measurements of the Mouse Aorta for Studies of Abdominal Aortic Aneurysms and Related Arterial Diseases (2011) (13)
- Impact of expanded FDA indication for icosapent ethyl on enhanced cardiovascular residual risk reduction. (2020) (12)
- Physiological relevance of apolipoprotein E recycling: studies in primary mouse hepatocytes. (2005) (12)
- Carotid Adventitial Vasa Vasorum and Intima‐Media Thickness in a Primary Prevention Population (2015) (12)
- ApoA-IV is secreted on discrete HDL particles by the rat hepatoma cell line McA-RH7777 transfected with ApoA-IV cDNA. (1993) (11)
- Use of PCSK9 Inhibitors in Solid Organ Transplantation Recipients (2020) (11)
- Lack of association between arterial blood pressure and erythrocyte fatty acid composition in an Italian population sample. (1987) (11)
- Putting Pleiotropy and Selection Into Context Defines a New Paradigm for Interpreting Genetic Data (2013) (11)
- Setting the Agenda for Preventive Cardiology (2017) (11)
- Presentation of the Rifle Project Risk-Factors and Life Expectancy (1993) (11)
- Importance of high-density lipoprotein quality: evidence from chronic kidney disease (2013) (11)
- Intake of polyunsaturated fat in relation to mortality among statin users and non-users in the Southern Community Cohort Study. (2015) (11)
- Brief Commentary: Marijuana and Cardiovascular DiseaseWhat Should We Tell Patients? (2019) (10)
- Evidence-based Management of Lipid Disorders (2011) (10)
- More Clinical Lessons from the FIELD Study (2009) (10)
- Molecular Characterization of Familial Hypercholesterolemia in a North American Cohort. (2019) (10)
- Identification of Small Proline-Rich Repeat Protein 3 as a Novel Atheroprotective Factor That Promotes Adaptive Akt Signaling in Vascular Smooth Muscle Cells (2014) (10)
- Stability and Reliability of Plasma Level of Lipid Biomarkers and Their Correlation with Dietary Fat Intake (2008) (10)
- Unusual responses to PCSK9 inhibitors in a clinical cohort utilizing a structured follow-up protocol (2020) (9)
- Debate: "How low should LDL cholesterol be lowered?" Viewpoint: "It doesn't need to be very low" (2001) (9)
- PCSK 9 Association With Lipoprotein ( a ) (2016) (9)
- Elevated lipoprotein(a) levels lower ABCA1 cholesterol efflux capacity. (2019) (9)
- Recent insights into the pathogenesis of type III hyperlipoproteinemia. (1993) (9)
- Interplay between apolipoprotein E and scavenger receptor class B type I controls coronary atherosclerosis and lifespan in the mouse. (2005) (9)
- Discordant responses of plasma low-density lipoprotein cholesterol and lipoprotein(a) to alirocumab: A pooled analysis from 10 ODYSSEY Phase 3 studies. (2021) (9)
- Killing two birds with one stone, maybe: CETP inhibition increases both high-density lipoprotein levels and insulin secretion. (2013) (9)
- The role of PCSK9 in intestinal lipoprotein metabolism: synergism of statin and ezetimibe. (2015) (9)
- Benzo[a]pyrene Potentiates the Pathogenesis of Abdominal Aortic Aneurysms in Apolipoprotein E Knockout Mice (2012) (9)
- Sex-Specific Parental Effects on Offspring Lipid Levels (2015) (8)
- Subcellular diversion of cholesterol by gain‐ and loss‐of‐function mutations in PMP22 (2020) (8)
- A case of severe acquired hypertriglyceridemia in a 7-year-old girl. (2017) (8)
- Comparison of Medical Care Utilization and Costs Among Patients With Statin-Controlled Low-Density Lipoprotein Cholesterol With Versus Without Hypertriglyceridemia. (2018) (7)
- Co-expression of cholesteryl ester transfer protein and defective apolipoprotein E in transgenic mice alters plasma cholesterol distribution. Implications for the pathogenesis of type III hyperlipoproteinemia. (1994) (7)
- Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice[S] (2014) (7)
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis (DOI:10.1016/j.cmet.2006.02.010) (2006) (7)
- Discordant responses of plasma low-density lipoprotein cholesterol and lipoprotein(a) to alirocumab: A pooled analysis from 10 ODYSSEY Phase 3 studies. (2020) (7)
- Real-world utilization of bempedoic acid in an academic preventive cardiology practice (2021) (7)
- Hepatic Sensing Loop Regulates PCSK9 Secretion in Response to Inhibitory Antibodies (2021) (7)
- Exercise is Associated With Increased Small HDL Particle Concentration and Decreased Vascular Stiffness in Rheumatoid Arthritis (2018) (6)
- Incident diabetes and statins: the blemish of an undisputed heavy weight champion? (2013) (6)
- The role of statin therapy in primary hyperlipidemia and mixed dyslipidemia (2011) (6)
- Abstract 15960: Macrophage IKKalpha Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival and Decreases Early Atherosclerosis (2013) (6)
- Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol: a case for resistin. (2012) (6)
- Familial hypercholesterolemia related admission for acute coronary syndrome in the United States: Incidence, predictors, and outcomes. (2021) (5)
- Insights on the kinetics and dynamics of the furin-cleaved form of PCSK9. (2020) (5)
- Fenofibrate and risk of minor amputations in diabetes (2009) (5)
- Faculty Opinions recommendation of Comparative Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition and Statins on Postprandial Triglyceride-Rich Lipoprotein Metabolism. (2018) (5)
- Fibrates – The Other Life-saving Lipid Drugs (2005) (5)
- Insights into the kinetics and dynamics of the furin-cleaved form of PCSK9 (2020) (5)
- Macrophage LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Is Required for the Effect of CD47 Blockade on Efferocytosis and Atherogenesis—Brief Report (2021) (5)
- Race-Dependent Association of High-Density Lipoprotein Cholesterol Levels With Incident Coronary Artery Disease. (2022) (5)
- Balanced high fat diet reduces cardiovascular risk in obese women although changes in adipose tissue, lipoproteins, and insulin resistance differ by race. (2018) (5)
- High triglyceride to HDL cholesterol ratio is associated with increased coronary heart disease among White but not Black adults (2021) (5)
- Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis. (2019) (5)
- Preventive cardiology as a dedicated clinical service: The past, the present, and the (Magnificent) future (2020) (4)
- Real-world utilization of pharmacotherapy with new evidence-based cardiovascular indications in an academic preventive cardiology practice (2021) (4)
- PCSK 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein-B Lipoproteins Through Both LDL-Receptor Dependent and Independent Mechanisms Running title : (2014) (4)
- Lipid treatment status and goal attainment among patients with atherosclerotic cardiovascular disease in the United States: A 2019 update (2022) (4)
- Multi-centre study on completeness of urine collection in 11 European centres (1986) (4)
- When it looks like familial hypercholesterolemia...but is not. (2012) (4)
- Biologic bases of residual risk of cardiovascular events: A flawed concept (2018) (4)
- Effects of a nutraceutical combination on left ventricular remodeling and vasoreactivity in subjects with the metabolic syndrome. (2012) (4)
- Low levels of high-density lipoprotein cholesterol due to lecithin:cholesterol acyltransferase mutations increase carotid atherosclerosis. (2011) (4)
- Familial Hypercholesterolemia: Genes and Beyond (2000) (4)
- Plasma Lipidomic Patterns in Patients with Symptomatic Coronary Microvascular Dysfunction (2021) (4)
- PREVENTIVE CARDIOLOGY AS NEW SUBSPECIALTY OF CARDIOVASCULAR MEDICINE. (2020) (3)
- "Taking a look under the hood"-imaging the phenotypic heterogeneity of familial hypercholesterolemia. (2018) (3)
- LOW HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND INCIDENT CORONARY HEART DISEASE AMONG WHITES IN THE REASONS FOR GEOGRAPHIC AND RACIAL DIFFERENCES IN STROKE (REGARDS) STUDY (2016) (3)
- Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches (2021) (3)
- PCSK9, a novel target for lowering LDL cholesterol: promise and progress (2012) (3)
- Application of PCSK 9 Inhibitors in Practice Challenges and Opportunities (2017) (3)
- On the relationship between cholesterol lowering and coronary disease event rate. (1998) (3)
- Co-occurrence of heterozygous CREB3L3 and APOA5 nonsense variants and polygenic risk in a patient with severe hypertriglyceridemia exacerbated by estrogen administration. (2018) (3)
- Optimizing sodium-glucose co-transporter 2 inhibitor use in patients with heart failure with reduced ejection fraction: A collaborative clinical practice statement (2021) (3)
- Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 (2021) (3)
- Macrophage Lipoprotein Lipase Promotes Foam Cell Formation and Atherosclerosis in LDL receptor Deficient Mice (2000) (2)
- Medication‐based versus target‐based lipid management (2018) (2)
- Acyl-CoA : Cholesterol Acyltransferase Promotes Oxidized LDL / Oxysterol-Induced Apoptosis in Macrophages (2005) (2)
- Familial Hypercholesterolemia: Use of Registries, Biobanks, and Cohort Studies To Improve its Diagnosis and Management in Non-Western Populations (2018) (2)
- Peeking into a cool future: genome editing to delete PCSK9 and control hypercholesterolemia in a single shot. (2014) (2)
- Lipoprotein(a) (2020) (2)
- Aborted Sudden Cardiac Death in Young Man with Familial Hypercholesterolemia: A Case Report and Review of The Literature (2018) (2)
- CHAPTER 2 – Regulation and Clearance of Apolipoprotein B–Containing Lipoproteins (2009) (2)
- Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs (2017) (2)
- Short-term treatment with a lipid-lowering agent: Diethylaminoethyldextran (Dexide). Excretion of bile acids, neutral sterols and faecal fats (1982) (2)
- Serum PCSK9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation (2013) (2)
- Aggressive Treatment for Severe Forms of Familial Hypercholesterolemia. (2020) (2)
- PCSK9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein-B Lipoproteins Through Both LDL-Receptor Dependent and Independent Mechanisms Running title: Rashid et al.; PCSK9 Promotes Intestinal ApoB Overproduction (2014) (2)
- The recycling of apolipoprotein E in macrophages Published, JLR Papers in Press, April 1, 2005. DOI 10.1194/jlr.M400418-JLR200 (2005) (2)
- Abstract P044: Alcohol Consumption, Statin Use and Risk of All-Cause Mortality in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort (2015) (1)
- Increased Cardiovascular Risk in Patients with Diabetes, Statin-Controlled LDL Cholesterol, and Residual Hypertriglyceridemia (2018) (1)
- Is it Time to Enhance Assessment of Alcohol Intake in Patients Slated for Statin Therapy? (2014) (1)
- Simulation of lipid-lowering therapy (LLT) intensification in very high-risk patients with atherosclerotic cardiovascular disease. (2022) (1)
- Dyslipidemias in children. (2012) (1)
- The link between lipids, statins and cancer: is there a role for cardio-oncology? (2015) (1)
- A new age of discovery for plasma lipoproteins. (2007) (1)
- Abstract 19083: Macrophage Expression of Pcsk9 Influences Atherosclerosis Development (2013) (1)
- 82 COMBINATION EZETIMIBE/SIMVASTATIN + EXTENDED-RELEASE NIACIN THERAPY IMPROVES ATTAINMENT OF RECOMMENDED LDL-C, NON-HDL-C AND APOB LEVELS IN HYPERLIPIDEMIC PATIENTS (2011) (1)
- Withdrawn: "Taking a look under the hood"-Imaging the phenotypic heterogeneity of familial hypercholesterolemia. (2018) (1)
- PCSK9 promotes intestinal overproduction of apolipoprotein-b lipoproteins through ldl-receptor dependent and independent mechanisms (2014) (1)
- Pharmacogenomic Study of Statin-Associated Muscle Symptoms in the ODYSSEY OUTCOMES Trial (2022) (1)
- [Effects of the integration of a habitual diet with glucomannan fiber in hypercholesterolemia. A clinical study in familial and sporadic hyperlipoproteinemia with lipo-proteic phenotype IIa and IIb]. (1986) (1)
- Genetic Disorders of HDL Metabolism (2015) (1)
- Dyslipidaemia: The PCSK9 adventure — humanizing extreme LDL lowering (2017) (1)
- Transiently achieved very low low-density lipoprotein cholesterol levels by statin and alirocumab after acute coronary syndrome are associated with cardiovascular risk reduction: the ODYSSEY OUTCOMES trial (2023) (1)
- 59 RELATIONSHIPS BETWEEN HSCRP REDUCTION AND LDL-C, NONHDL-C, APOB AND HDL-C IN HYPERLIPIDEMIC PATIENTS TREATED WITH EZETIMIBE/SIMVASTATIN + EXTENDED-RELEASE NIACIN (2011) (1)
- Faculty Opinions recommendation of Safety and efficacy of bempedoic acid to reduce LDL cholesterol. (2019) (1)
- Apolipoprotein E and Reverse Cholesterol Transport: The Role of Recycling in Plasma and Intracellular Lipid Trafficking (2007) (1)
- DOES LOW HDL-C INCREASE CHD RISK WHEN TG & LDL-C ARE NORMAL? THE FRAMINGHAM OFFSPRING STUDY (2014) (1)
- Unmet Needs in Understanding Lipoprotein(a) Pathophysiology: NHLBI Working Group Recommendations to Reduce Risk of Cardiovascular Disease and Aortic Stenosis (2018) (1)
- Association-of-Serum-Selenium-with-Selected-Cardiovascular-Risk-Factors 1995 Microchemical-Journal (1995) (1)
- activity of this receptor related protein explains the antiinflammatory − pathway by LDL receptor B κ Regulation of tumor necrosis factor receptor-1 and the IKK (2008) (1)
- The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment Published, JLR Papers in Press, May 16, 2004. DOI 10.1194/jlr.M400104-JLR200 (2004) (1)
- PREDICTING HYPERTRIGLYCERIDEMIC PANCREATITIS - NOT SO FAST! (2018) (1)
- Long-term Effect of Triple Combination Ezetimibe/Simvastatin+Extended-Release Niacin on Cholesterol Content of Lipoprotein Subclasses in Hyperlipidemic Patients (2009) (1)
- Abstract 4: Deletion of Macrophage Low-density Lipoprotein Receptor-related Protein 1 (LRP1) Accelerates Atherosclerosis Regression by Increasing CCR7-dependent Egress of Plaque Macrophages (2017) (1)
- Faculty Opinions recommendation of Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study. (2017) (0)
- The Potential of Electronic Health Record Data to Optimize Recruitment Efficiency in Cardiovascular Outcome Trials (2017) (0)
- Faculty Opinions recommendation of Cardiovascular events in patients under age fifty with early findings of elevated lipid and glucose levels - The AMORIS study. (2018) (0)
- Faculty Opinions recommendation of Persistent arterial wall inflammation in patients with elevated lipoprotein(a) despite strong low-density lipoprotein cholesterol reduction by proprotein convertase subtilisin/kexin type 9 antibody treatment. (2018) (0)
- Faculty Opinions recommendation of Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease. (2019) (0)
- Abstract 16265: Acute Coronary Syndrome in Patients With Familial Hypercholesterolemia: Incidence, Predictors, and Outcomes (2020) (0)
- Abstract: P1443 LONG-TERM EFFECT OF COMBINATION EZETIMIBE/SIMVASTATIN + EXTENDED-RELEASE NIACIN (E/S+N) ON LIPOPROTEIN SUBCLASSES IN PATIENTS WITH HYPERLIPIDEMIA (HL) (2009) (0)
- Faculty Opinions recommendation of Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity. (2019) (0)
- Faculty Opinions recommendation of Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council. (2016) (0)
- Abstract 033: Differential Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Production and Function on Microsomal Triglyceride Transfer Protein (2018) (0)
- 0156 Both Circadian Clock And Sleep Control Plasma Levels Of Pcsk9, The Main Regulator Of Plasma Ldl Cholesterol (2019) (0)
- Abstract 198: HDL Function and Genetic Regulation in a Nonhuman Primate Model of HDL Cholesterol Extremes (2016) (0)
- Faculty Opinions recommendation of Repositioning of the Global Epicentre of Non-Optimal Cholesterol. (2020) (0)
- Faculty Opinions recommendation of Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol. (2019) (0)
- Abstract 282: Pattern of Development of Abdominal Aortic Aneurysms Induced by Angiotensin In Hypercholesterolemic Mice (2013) (0)
- Abstract: 1006 EZETIMIBE/SIMVATASTATIN (E/S) PLUS EXTENDED RELEASE NIACIN (N) IN HYPERLIPIDEMIA (HL) PATIENTS WITH DIABETES (DM) OR METABOLIC SYNDROME (MS) (2009) (0)
- Abstract 434: LDL Apheresis Significantly Alters HDL Cargo and Function in Familial Hypercholesterolemia Subjects (2014) (0)
- Abstract 561: Reduced Serum Efflux Capacity Associates With Elevated Plasma Lp(a) Levels (2018) (0)
- Binding of PCSK9 to circulating LDL: Effect of PCSK9 monoclonal antibodies on the LDL-bound PCSK9? (2018) (0)
- Association between Plasma PCSK9 levels and Presence of Coronary Artery Calcium (2020) (0)
- Faculty Opinions recommendation of Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease. (2019) (0)
- DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, CARDIOVASCULAR, AND CANCER CENTER 2013-2014 SEMINAR SCHEDULE* Please obtain prior approval when inviting a guest speaker from Dr. Di Cera. DATE SPEAKER HOST (2014) (0)
- Abstract 29: Novel Atheroma-specific Atheroprotective Factor Promotes VSMC Pro-survival Signaling (2014) (0)
- Faculty Opinions recommendation of Coronary Artery Calcium and Cardiovascular Events in Patients With Familial Hypercholesterolemia Receiving Standard Lipid-Lowering Therapy. (2018) (0)
- Abstract 565: Effects of PCSK9 Inhibition on Plasma PCSK9 Concentration and Hepatic PCSK9 Expression (2018) (0)
- COMBINATION EZETIMIBE/SIMVASTATIN + EXTENDED-RELEASE NIACIN THERAPY IMPROVES ATTAINMENT OF RECOMMENDED LEVELS OF LDL-C, NON-HDL-C AND APO B IN HYPERLIPIDEMIC PATIENTS (2011) (0)
- Abstract 156: Macrophage Low-Density Receptor--Related Protein 1 Deficiency Facilitates Atherosclerosis Regression in Hyperlipidemic Mice (2014) (0)
- Response by Mueller et al to Letter Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages". (2019) (0)
- Faculty Opinions recommendation of PCSK9 inhibition with alirocumab reduces lipoprotein (a) levels in non-human primates by lowering apolipoprotein (a) production rate. (2018) (0)
- Abstract 240: Serum Cholesterol and Angiotensin-Induced Abdominal Aortic Aneurysm in Hypercholesterolemic Mice (2013) (0)
- Faculty Opinions recommendation of Gene-Based Elevated Triglycerides and Type 2 Diabetes Mellitus Risk in the Women's Genome Health Study. (2018) (0)
- Abstract 276: SR-BI Suppresses Apoptosis by Reducing Endoplasmic Reticulum Stress and Promoting Akt Activity in Macrophages (2014) (0)
- HIGH HDL CHOLESTEROL LEVELS AND MARKERS OF INFLAMMATION AND METABOLIC HEALTH IN PATIENTS HOSPITALIZED WITH ACUTE MYOCARDIAL INFARCTION (2010) (0)
- Abstract 19075: Impact of LDL Apheresis on Lipoprotein Particle Concentrations (2012) (0)
- Role of PAI-1 in hepatic steatosis and dyslipidemia (2021) (0)
- Abstract 17189: Indications and Adverse Effects of Statin Therapy in Children: A Retrospective Electronic Medical Record Review (2016) (0)
- Abstract 197: Characterization of the Effects of Angiopoietin-Like 3 on Plasma Lipids and Lipoproteins in Humans (2017) (0)
- Faculty Opinions recommendation of The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis: a triumph of simplicity. (2017) (0)
- APPLICATION OF LOW-DENSITY LIPOPROTEIN CHOLESTEROL POLYGENIC RISK SCORE ANALYSIS IN PATIENTS WITH REFRACTORY HYPERCHOLESTEROLEMIA (2023) (0)
- Abstract 14161: Increased Cardiovascular Risk in Patients With Statin-Controlled LDL Cholesterol and Residual Hypertriglyceridemia (2017) (0)
- Faculty Opinions recommendation of Association of migraine with aura and other risk factors with incident cardiovascular disease in women. (2020) (0)
- CAROTID ADVENTITIAL NEOVASCULARIZATION AND INTIMA–MEDIA THICKNESS AS MARKERS OF ATHEROGENESIS: EVIDENCE FROM TWO RANDOMIZED CONTROLLED TRIALS (2013) (0)
- Faculty Opinions recommendation of Time course of LDL cholesterol exposure and cardiovascular disease event risk. (2020) (0)
- Abstract: 1007 NEW ONSET DIABETES MELLITUS (DM) IN PATIENTS WITH HYPERLIPIDEMIA (HL) TAKING EZETIMIBE/SIMVASTATIN (E/S) +/− NIACIN (N) (2009) (0)
- Editorial Board (2009) (0)
- Abstract 312: Enhanced Systemic Inflammation Accelerates Plaque Reduction Following Lipid Lowering Therapy in Mice (2020) (0)
- Abstract P071: Association Between Polyunsaturated Fat Consumption and Hypertension among Statin Users and Non-users (2014) (0)
- Lipoprotein(a) Gets Worse. (2020) (0)
- Long-term Effect of Combination Ezetimibe/Simvastatin+Extended-Release Niacin on Cholesterol Content of Lipoprotein Subclasses in Patients with Hyperlipidemia (2009) (0)
- Abstract P100: Identification of Patients with Familial Hypercholesterolemia (FH) Using the Dutch Lipid Network (DLN) Criteria in Electronic Health Records (EHR) (2016) (0)
- SHORT-DURATION, VERY HIGH-INTENSITY LIPID-LOWERING THERAPY RESULTS IN PROLONGED REDUCTION OF CARDIOVASCULAR EVENTS FOLLOWING ACUTE CORONARY SYNDROME (2023) (0)
- Long-term Safety and Efficacy of Triple Combination Ezetimibe/Simvastatin + Extended-Release Niacin in Hyperlipidemic Patients (2009) (0)
- Faculty Opinions recommendation of Causal Inference for Genetically Determined Levels of HDL (High-Density Lipoprotein) Cholesterol and Risk of Infectious Disease. (2019) (0)
- Faculty of 1000 evaluation for From High-Density Lipoprotein Cholesterol to Measurements of Function: Prospects for the Development of Tests for High-Density Lipoprotein Functionality in Cardiovascular Disease. (2018) (0)
- Abstract 396: A Unique Case of Artefactual and Real HDL Disappearance Due to Isolevuglandins Adducts (2018) (0)
- Faculty of 1000 evaluation for Lp(a) (Lipoprotein(a)) Levels Predict Progression of Carotid Atherosclerosis in Subjects With Atherosclerotic Cardiovascular Disease on Intensive Lipid Therapy: An Analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycer (2018) (0)
- Abstract 632: Modification of HDL by γ-Ketoaldehydes Causes impaired HDL Function in Familial Hypercholesterolemia (2016) (0)
- SAFETY AND TOLERABILITY OF THE TRIPLE COMBINATION EZETIMIBE/SIMVASTATIN + EXTENDED RELEASE NIACIN IN HYPERLIPIDEMIA PATIENTS (2008) (0)
- RACIAL DIFFERENCES IN THE PREVALENCE OF UNCONTROLLED AND UNREPORTED HYPERTENSION IN THE SOUTHEASTERN UNITED STATES: INSIGHTS FROM ALMOST 70,000 BLACKS AND WHITES IN THE SOUTHERN COMMUNITY COHORT STUDY (2013) (0)
- Faculty of 1000 evaluation for Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease. (2018) (0)
- CORONARY MICROVASCULAR DYSFUNCTION BY MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY IN NON-ELDERLY PATIENTS REFERRED FOR CT CORONARY ANGIOGRAPHY (2019) (0)
- Abstract 239: LDL Apheresis Is Associated With a Reduction in Markers of Chronic Inflammation in Patients With Familial Hypercholesterolemia (2014) (0)
- Plasma lipid levels and colorectal adenoma risk (2015) (0)
- Abstract 10118: PCSK9 Inhibition Augments the Therapeutic Effect of Ezetimibe in Lowering Intestinal Apolipoprotein B Lipoprotein Production (2013) (0)
- Circulation Research. (2016) (0)
- Quantum Dot - Mediated Imaging of Vascular Disease (2008) (0)
- Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis (2022) (0)
- Abstract 17184: Achievement Of LDL-cholesterol Reduction Targets is Associated With Reduced Cardiovascular Disease Risk Among Patients With Familial Hypercholesterolemia in a Large Electronic Medical Record Database (2015) (0)
- Abstract 479: Expression of ApoE-sendai by Macrophages Causes Lipoprotein Glomerulopathy While Suppressing Atherosclerosis (2013) (0)
- Abstract P150: Association of Cholesterol Measures With Coronary Heart Disease Risk in Blacks and Whites in the Reasons for Geographic and Racial Differences in Stroke Study (regards) (2020) (0)
- Faculty Opinions recommendation of HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells. (2017) (0)
- The Apolipoprotein E Cys-142 Mutant: Role in Dominant Inheritance of Type III Hyperlipoproteinemia and Expression in Transgenic Mice (1993) (0)
- L1 Tie1 ATTENUATION RESULTS IN A LOCATION-SPECIFIC AND SHEAR STRESS-DEFINED REDUCTION IN ATHEROSCLEROSIS (2010) (0)
- Erratum: Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis (2010) (0)
- Author response for "Risk of Cardiovascular Events in Patients with Hypertriglyceridemia: A Review of Real‐World Evidence" (2019) (0)
- Abstract 19057: Macrophage SR-BI Deletion Promotes Defective Efferocytosis via Src/Akt/Rac1 Signaling Pathway Resulting in Increased Atherosclerotic Lesion Necrosis (2013) (0)
- Genetic Data Putting Pleiotropy and Selection Into Context Defines a New Paradigm for Interpreting (2013) (0)
- Ezetimibe/Simvastatin + Extended Release Niacin Therapy Improves Attainment of Recommended Levels of LDL-C, Non-HDL-C, and ApoB in Hyperlipidemic Patients† (2011) (0)
- Abstract P555: Plasma Lipids And The Risk For Stroke In The Reasons For Geographic And Racial Differences In Stroke Study (regards). (2020) (0)
- Faculty Opinions recommendation of Cholesterol Lowering and Stroke: No Longer Room for Pleiotropic Effects of Statins - Confirmation from PCSK9 Inhibitor Studies. (2019) (0)
- Metabolic syndrome predicts adverse cardiovascular risk among the elderly (2005) (0)
- PCSK9 inhibition augments the therapeutic effect of ezetimibe in lowering intestinal apolipoprotein B lipoprotein production (2014) (0)
- Faculty Opinions recommendation of Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis. (2017) (0)
- Faculty of 1000 evaluation for APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation and Meta-Analyses of 137 895 Individuals. (2018) (0)
- INCREASED MEDICAL CARE COSTS IN PATIENTS WITH STATIN-CONTROLLED LOW-DENSITY LIPOPROTEIN CHOLESTEROL AND RESIDUAL HYPERTRIGLYCERIDEMIA (2018) (0)
- [Prevention of cardiovascular diseases]. (1988) (0)
- Faculty Opinions recommendation of Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease. (2019) (0)
- Triple Combination Ezetimibe/Simvas tatin + Extended-Relea se Niacin Therapy Improves Ratios of ApoB/ApoA-I Containing Lipoproteins in Hyperlipidemi a Patients (2008) (0)
- byinhibitingfatty-acid-bindingproteinaP2 (2007) (0)
- Abstract 123: Reciprocal Regulation of Plasma PCSK9 and Cell-surface Low-density Lipoprotein Receptor (2013) (0)
- Is There A Role for Fibrate Therapy in the Management of Dyslipidemia (2015) (0)
- Physiological Levels of PCSK9 Promote Hepatic and Intestinal Overproduction of Apolipoprotein-B Lipoproteins Through LDl-Receptor Dependent and Independent Mechanisms (2013) (0)
- The American journal of preventive cardiology: On a mission to help define a specialty (2020) (0)
- Features of the most commonly used mouse models of dyslipidemia and atherosclerosis (2002) (0)
- Faculty Opinions recommendation of Statin therapy increases lipoprotein(a) levels. (2019) (0)
- Preventive Cardiology as Specialized Medical Art (2020) (0)
- Abstract 29: PCSK9 Association With Lipoprotein(a) (2015) (0)
- 6-Mercaptopurine, monocytes, and atherosclerosis. (2010) (0)
- Use of commercial genetic testing to help reclassify LDL receptor variants in clinical practice: A case report. (2021) (0)
- Faculty Opinions recommendation of Inflammasomes in health and disease. (2017) (0)
- Relationship Between HsCRP Reduction and LDL-C, Non-HDL-C, ApoB, and HDL-C in Hyperlipidemic Patients Treated with Ezetimibe/Simvastatin + Niaspan† (2011) (0)
- Abstract 180: Missense Mutations in ABCA1 and CETP Associate with Changes in the HDL Proteome in Primate Half-Sibs Discordant for HDL Cholesterol Levels (2018) (0)
- Faculty Opinions recommendation of Apolipoprotein(a) Kinetics in Statin-Treated Patients with Elevated Plasma Lipoprotein(a) Concentration. (2019) (0)
- Polyunsaturated fat intake and mortality in non-statin users, is there an independent relationship? The authors reply. (2016) (0)
- Expression of apoESendai by macrophages causes lipoprotein glomerulopathy while suppressing atherosclerosis (2014) (0)
- Faculty of 1000 evaluation for Genetic Factors Explain a Major Fraction of the 50% Lower LPA (Lipoprotein[a]) Concentrations in Finns. (2018) (0)
- Faculty Opinions recommendation of CAD severity on cardiac CTA identifies patients with most benefit of treating LDL cholesterol to ACC/AHA and ESC/EAS targets. (2020) (0)
- Response to Duell et al. (2014) (0)
- Faculty Opinions recommendation of Lipoprotein(a) Reduction in Persons with Cardiovascular Disease. (2020) (0)
- Inhibition of apolipoprotein(a) synthesis by farnesoid X receptor and fibroblast growth factor 15/19: a step toward selective lipoprotein(a) therapeutics. (2012) (0)
- Faculty Opinions recommendation of Cognition After Lowering LDL-Cholesterol With Evolocumab. (2020) (0)
- Faculty Opinions recommendation of Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol. (2020) (0)
- Abstract 15417: Macrophage Deficiency of Akt2 or Both Akt1 and Akt2 Reduces Atherosclerosis: Akt is Critical for Macrophage Polarization and Survival (2013) (0)
- Variable responses to a hypercholesterol diet in a group of adult male volunteers (1988) (0)
- Response to letter regarding article, "Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms". (2015) (0)
- Serum cholesterol and the risk of developing hormonally driven cancers: A narrative review (2022) (0)
- TIME AND DOSE-RELATED EFFECTS ON THE LIPID PROFILE IN HYPERLIPIDEMIA PATIENTS FOLLOWING TRIPLE COMBINATION THERAPY WITH EZETIMIBE/SIMVASTATIN + NIACIN (2008) (0)
- Result of Genetic Analysis in FH Case (2018) (0)
- [The role of fish fats in the prevention of arteriosclerosis]. (1987) (0)
- Faculty Opinions recommendation of Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records. (2018) (0)
- Progress in Cardiovascular (2009) (0)
- Faculty Opinions recommendation of Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans. (2020) (0)
- Faculty of 1000 evaluation for Genetics, Lifestyle, and Low-Density Lipoprotein Cholesterol in Young and Apparently Healthy Women. (2018) (0)
- Treating the Common Dyslipidemia in Patients with Type 2 Diabetes: Insights from FIELD on the Effects of Fenofibrate on CVD Risk (2006) (0)
- Selected for the National Lipid Association 2019 Scientific Sessions , May 16-19 , 2019 , Miami , FL 2019 Program Planners : (2019) (0)
- EFFICACY AND SAFETY OF EZETIMIBE/SIMVASTATIN COADMINISTERED WITH EXTENDED RELEASE NIACIN IN PATIENTS WITH TYPE IIA OR IIB HYPERLIPIDEMIA (2008) (0)
- The first mutations of the LDL receptor gene found in Italians (1990) (0)
- Progressively decreasing plasma high-density lipoprotein cholesterol levels preceding diagnosis of smoldering myeloma. (2020) (0)
- WITHDRAWN: Raising the Bar by Lowering the Target: Integrating PCSK9 Inhibitors Into Hypercholesterolemia Management. (2018) (0)
- Faculty of 1000 evaluation for High-Density Lipoprotein Cholesterol and Mortality: Too Much of a Good Thing? (2018) (0)
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What Schools Are Affiliated With Sergio Fazio?
Sergio Fazio is affiliated with the following schools:
