Sergiu P. Pașca
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Most Influential Person Now
Associate Professor of Psychiatry and Behavioral Sciences
Sergiu P. Pașca's AcademicInfluence.com Rankings
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Psychology Biology
Sergiu P. Pașca's Degrees
- Masters Medicine Carol Davila University of Medicine and Pharmacy
- PhD Neuroscience Stanford University
Why Is Sergiu P. Pașca Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sergiu P. Pașca is a Romanian-American scientist and physician at Stanford University in California. He is known for creating and developing stem cell-based models of the human brain and applying organoids and assembloids to gain insights into neuropsychiatric disease.
Sergiu P. Pașca's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture (2015) (1038)
- Assembly of functionally integrated human forebrain spheroids (2017) (762)
- Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain (2015) (635)
- Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells (2017) (353)
- The rise of three-dimensional human brain cultures (2018) (301)
- Using iPS cell-derived neurons to uncover cellular phenotypes associated with Timothy Syndrome (2011) (299)
- Reliability of human 3D cortical organoid generation (2018) (254)
- Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons (2012) (227)
- Building Models of Brain Disorders with Three-Dimensional Organoids (2018) (205)
- Differentiation and Maturation of Oligodendrocytes in Human Three-Dimensional Neural Cultures (2018) (201)
- Generation and assembly of human brain region–specific three-dimensional cultures (2018) (199)
- Engineered materials for organoid systems (2019) (174)
- Generation of Functional Human 3D Cortico-Motor Assembloids (2020) (165)
- High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism. (2006) (154)
- Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells (2020) (131)
- Chromatin accessibility dynamics in a model of human forebrain development (2020) (131)
- Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment (2019) (130)
- Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution (2020) (122)
- Long Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions (2021) (120)
- The ethics of experimenting with human brain tissue (2018) (110)
- One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders (2008) (110)
- Organoid and Assembloid Technologies for Investigating Cellular Crosstalk in Human Brain Development and Disease. (2019) (107)
- Assembling human brain organoids (2019) (104)
- Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring (2017) (99)
- Human 3D Cellular Model of Hypoxic Brain Injury of Prematurity (2019) (96)
- A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients (2016) (94)
- Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals (2020) (89)
- MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis. (2017) (85)
- Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome (2014) (79)
- Neuronal defects in a human cellular model of 22q11.2 deletion syndrome (2020) (78)
- A framework for the investigation of rare genetic disorders in neuropsychiatry (2019) (73)
- Generating human neurons in vitro and using them to understand neuropsychiatric disease. (2014) (68)
- The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression (2018) (61)
- Cell diversity in the human cerebral cortex: from the embryo to brain organoids (2019) (54)
- A tissue-like neurotransmitter sensor for the brain and gut (2022) (53)
- Motor abnormalities as a putative endophenotype for Autism Spectrum Disorders (2013) (43)
- Human brain organogenesis: Toward a cellular understanding of development and disease (2021) (39)
- A Promoter in the Coding Region of the Calcium Channel Gene CACNA1C Generates the Transcription Factor CCAT (2013) (37)
- Maturation and circuit integration of transplanted human cortical organoids (2022) (35)
- Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia (2018) (32)
- SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer (2019) (31)
- Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome. (2021) (31)
- Primate cell fusion disentangles gene regulatory divergence in neurodevelopment (2021) (31)
- Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome (2019) (30)
- Advancing models of neural development with biomaterials (2021) (30)
- Paraoxonase 1 activities and polymorphisms in autism spectrum disorders (2008) (30)
- Neural Differentiation in the Third Dimension: Generating a Human Midbrain. (2016) (29)
- Engineering brain assembloids to interrogate human neural circuits (2022) (27)
- Exosome-carried microRNA-based signature as a cellular trigger for the evolution of chronic lymphocytic leukemia into Richter syndrome (2018) (27)
- A nomenclature consensus for nervous system organoids and assembloids (2022) (24)
- Building three-dimensional human brain organoids (2018) (24)
- MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases (2020) (24)
- Role of Key Micronutrients from Nutrigenetic and Nutrigenomic Perspectives in Cancer Prevention (2019) (23)
- A narrative review of central nervous system involvement in acute leukemias (2021) (17)
- Nanotechnology Enables Novel Modalities for Neuromodulation (2021) (17)
- Approach to the Adult Acute Lymphoblastic Leukemia Patient (2019) (16)
- Behavioral effects of corpus callosum transection and environmental enrichment in adult rats (2006) (16)
- Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease (2019) (16)
- Antiproliferative effects of propofol and lidocaine on the colon adenocarcinoma microenvironment. (2019) (15)
- Minimal residual disease in chronic lymphocytic leukemia: A consensus paper that presents the clinical impact of the presently available laboratory approaches (2018) (15)
- Targeting the Microenvironment in MDS: The Final Frontier (2020) (14)
- Reliability of human cortical organoid generation (2018) (14)
- Engineering a Genetically Encoded Magnetic Protein Crystal. (2019) (14)
- Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? (2020) (13)
- Polarizing brain organoids (2019) (13)
- KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma (2019) (12)
- Fibroblast dynamics as an in vitro screening platform for anti‐fibrotic drugs in primary myelofibrosis (2018) (11)
- Clinical Approach to the Patient in Critical State Following Immunotherapy and/or Stem Cell Transplantation: Guideline for the On-Call Physician (2019) (11)
- The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C (2021) (11)
- Day 15 and Day 33 Minimal Residual Disease Assessment for Acute Lymphoblastic Leukemia Patients Treated According to the BFM ALL IC 2009 Protocol: Single-Center Experience of 133 Cases (2020) (10)
- Let’s Talk About BiTEs and Other Drugs in the Real-Life Setting for B-Cell Acute Lymphoblastic Leukemia (2019) (10)
- Medical Application of Hydrogen in Hematological Diseases (2019) (9)
- Persistent Basophilia May Suggest an “Accelerated Phase” in the Evolution of CALR-Positive Primary Myelofibrosis Toward Acute Myeloid Leukemia (2019) (9)
- Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome (2021) (9)
- Transforming growth factor β‐mediated micromechanics modulates disease progression in primary myelofibrosis (2020) (9)
- Chromatin dynamics in human brain development and disease. (2021) (8)
- Serum paraoxonase 1 activities and homocysteinemia in hemodialysis patients (2008) (8)
- Clonal hematopoiesis and bone marrow failure syndromes. (2021) (7)
- Basic knowledge on BCR-ABL1-positive extracellular vesicles. (2020) (7)
- Human assembloids. (2022) (7)
- Vomiting is not an adaption for glaucoma (and Darwinian medicine is difficult). (2008) (7)
- Next-generation sequencing-based characterization of the invasion by anatomical contiguity in a primary osseous diffuse large B-cell lymphoma. Correlation between the genetic profile of the malignancy and the clinical outcome of the patient. (2019) (7)
- Personalized Human Cortical Spheroids. (2016) (6)
- Transient leukemia of Down syndrome (2019) (6)
- SERS-based DNA methylation profiling allows the differential diagnosis of malignant lymphadenopathy. (2021) (6)
- Single-Center Experience With Epigenetic Treatment for Juvenile Myelomonocytic Leukemia (2020) (6)
- Genetically enhanced T lymphocytes and the intensive care unit (2018) (5)
- CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development (2022) (5)
- Drinking Behavior, Taste Preferences and Special Beer Perception among Romanian University Students: A Qualitative Assessment Research (2021) (5)
- CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation (2020) (5)
- Assembly of Functional Forebrain Spheroids from Human Pluripotent Cells (2017) (5)
- The use of rotation to fentanyl in cancer-related pain (2017) (5)
- How collaboration between bioethicists and neuroscientists can advance research (2022) (4)
- The Potential Equivalents of TET2 Mutations (2021) (4)
- The hidden biology of the human brain (2019) (4)
- Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology (2019) (4)
- Mental Fatigue Evaluation of Surgical Teams during a Regular Workday in a High-Volume Tertiary Healthcare Center (2020) (4)
- The Influence of Methylating Mutations on Acute Myeloid Leukemia: Preliminary Analysis on 56 Patients (2020) (4)
- Surround modulation of neuronal responses in V1 is as stable over time as responses to direct stimulation of receptive fields (2010) (4)
- From Proteomics to Personalized Medicine: The Importance of Isoflavone Dose and Estrogen Receptor Status in Breast Cancer Cells (2020) (4)
- Current therapeutic approaches in the management of hemophilia—a consensus view by the Romanian Society of Hematology (2021) (4)
- Differential Diagnosis of Malignant Lymphadenopathy Using Flow Cytometry on Fine Needle Aspirate: Report on 269 Cases (2020) (4)
- Biocompatible polymers for scalable production of human neural organoids (2022) (4)
- A matter of space and time: Emerging roles of disease-associated proteins in neural development (2021) (4)
- Research and training in autism spectrum disorder to catalyze the next genomic and neuroscience revolutions (2020) (4)
- The Predictive Role of Modified Early Warning Score in 174 Hematological Patients at the Point of Transfer to the Intensive Care Unit (2021) (3)
- Ibrutinib Monotherapy as Bridge-to-Transplant for Relapsed/Refractory Primary Oculo-Cerebral Lymphoma (2021) (3)
- Research regarding variation of muscular fiber diameter from Oncorhynchus mykiss, Salmo trutta fario and Salvelinus fontinalis breed farmed in ne part of Romania. (2013) (3)
- MicroRNA-155-5p Plays a Critical Role in Transient Leukemia of Down Syndrome by Targeting Tumor Necrosis Factor Receptor Superfamily Members. (2020) (3)
- SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome (2021) (3)
- Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia/Lymphoma—Romanian Experience (2020) (3)
- Mapping human brain organoids on a spatial atlas. (2021) (3)
- SERS-Based Assessment of MRD in Acute Promyelocytic Leukemia? (2020) (3)
- Unexplained hemorrhagic syndrome? Consider acquired hemophilia A or B. (2021) (3)
- What Have Organoids and Assembloids Taught Us About the Pathophysiology of Neuropsychiatric Disorders? (2022) (3)
- Focus on organoids: cooperation and interconnection with extracellular vesicles – is this the future of in vitro modeling? (2021) (3)
- Landscape of human spinal cord cell type diversity at midgestation (2021) (3)
- Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model (2022) (3)
- B Cells versus T Cells in the Tumor Microenvironment of Malignant Lymphomas. Are the Lymphocytes Playing the Roles of Muhammad Ali versus George Foreman in Zaire 1974? (2020) (2)
- Feeder-free, Xeno-free Generation of Cortical Spheroids From Human Pluripotent Stem Cells (2018) (2)
- Absent forebrain replaced by embryonic stem cells (2018) (2)
- Baseline characteristics of a nationwide cohort of pediatric patients with acute leukemias of Down syndrome. (2020) (2)
- Faculty Opinions recommendation of Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects. (2016) (2)
- Azacytidine plus olaparib for relapsed acute myeloid leukaemia, ineligible for intensive chemotherapy, diagnosed with a synchronous malignancy (2021) (2)
- Characteristics of Dental Resin-Based Composites in Leukemia Saliva: An In Vitro Analysis (2021) (2)
- Overview of the Side-Effects of FDA- and/or EMA-Approved Targeted Therapies for the Treatment of Hematological Malignancies (2020) (2)
- Stretchable mesh microelectronics for the biointegration and stimulation of human neural organoids. (2022) (2)
- Method of DNA Analysis Using the Estimation of the Algorithmic Complexity (2005) (2)
- P.3.b.010 Markers of oxidative stress in patients with schizophrenia and metabolic syndrome. Preliminary study (2008) (2)
- Haematology patients infected with SARS-CoV-2, pretreated with eculizumab or siltuximab, develop oligosymptomatic disease (2021) (1)
- Mad Neanderthal disease? Some comments on ''A potential role for Transmissible Spongiform Encephalopathies in Neanderthal extinction'' (2008) (1)
- Imaging neuronal migration and network activity in human forebrain assembloids (2022) (1)
- TET2/IDH1/2/WT1 and NPM1 Mutations Influence the RUNX1 Expression Correlations in Acute Myeloid Leukemia (2020) (1)
- Correction: Genetically enhanced T lymphocytes and the intensive care unit (2018) (1)
- The Zika threat to the periphery (2017) (1)
- ASSEMBLING THREE-DIMENSIONAL MODELS OF THE BRAIN TO STUDY HUMAN DEVELOPMENT AND DISEASE (2019) (1)
- Investigation of the paraoxonase 1 (PON1) promoter polymorphism C(-108)T and activities in autism spectrum disorders. (2009) (1)
- Implications of TET2 in CAR-T Cell Activity and Target Response to CAR-T Cell Therapy: Lessons Learned from T Cells. (2021) (1)
- Complete metabolic remission in an 84-year old patient with relapsed/refractory diffuse large B-cell lymphoma following combination immunotherapy with lenalidomide plus rituximab (2020) (1)
- Genetic polymorphisms of cytokines in asthma and allergic rhinitis (2020) (1)
- Characterization of extrachromosomal circular DNA in patients with acute myeloid leukemia: proof-of-concept report using cohorts from Beijing and Shanghai (2022) (1)
- Angioimmunoblastic T cell Lymphoma Microenvironment (2020) (1)
- Generation and Assembly of Forebrain Spheroids (2017) (1)
- Author response: A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients (2016) (1)
- Correlation between the prevalence of T-cell lymphomas and alcohol consumption. (2021) (0)
- Engineering a Magnetic Protein Crystal (2020) (0)
- Human 3D cellular model of hypoxic brain injury of prematurity (2019) (0)
- Engineering brain assembloids to interrogate human neural circuits (2022) (0)
- Absent forebrain replaced by embryonic stem cells (2018) (0)
- A cross-sectional study of the neuropsychiatric phenotype of CACNA1C-related disorder (2022) (0)
- Three-Dimensional Assembly of The Human Forebrain In Vitro To Study Development and Psychiatric Disorders (2019) (0)
- Paraoxonase 1 Status, Environmental Exposures, and Oxidative Stress in Autism Spectrum Disorders (2009) (0)
- The Usefulness of Biomarkers for Diagnosis (2020) (0)
- Mesh electrode arrays for integration with electrogenic organoids (2022) (0)
- Epidemiological surveillance of wild animals populations in north Moldavia in 2006-2008. (2010) (0)
- Polarizing brain organoids (2019) (0)
- Mouse embryo models built from stem cells take shape in a dish (2022) (0)
- Author response: Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome (2019) (0)
- Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome (2014) (0)
- Circulating microRNA-194 and microRNA-1228 Could Predict Colon Cancer Proliferation via Phospho S6 Modulation. (2020) (0)
- A Cross-Sectional Study of the Neuropsychiatric Phenotype of CACNA1C-Related Disorder (P11-9.004) (2023) (0)
- The ethics of experimenting with human brain tissue (2018) (0)
- The Presence of Periodontitis in Patients with Von Willebrand Disease: A Systematic Review (2021) (0)
- Reconstruction techniques in the odontal injuries in dogs. (2011) (0)
- A human cellular model of amyotrophic lateral sclerosis (2018) (0)
- The importance of MLH1, MSH2, MSH6 and PMS2 in determining DNA damage response in digestive cancers (2021) (0)
- Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway (2023) (0)
- Stretchable mesh microelectronics for the biointegration and stimulation of neural organoids (2022) (0)
- Single-cell transcriptomic landscape of the developing human spinal cord. (2023) (0)
- 252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System (2016) (0)
- Clinical Remission in a 72-Year-Old Patient with a Massive Primary Cutaneous Peripheral T-Cell Lymphoma-NOS of the Eyelid, Following Combination Chemotherapy with Etoposide Plus COP (2020) (0)
- Topical Corticosteroids a Viable Solution for Oral Graft versus Host Disease? A Systematic Insight on Randomized Clinical Trials (2020) (0)
- Comparison of peripheral blood stem cell mobilization with filgrastim versus pegfilgrastim in lymphoma patients - single center experience. (2021) (0)
- The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression (2018) (0)
- Clonal Hematopoiesis Is More Common in People Living with HIV and May be Associated with Increased Prevalence of Cardiovascular Disease (2021) (0)
- Comparing aspects concerning the diagnose value of CT scan and MRA tehnic in a case of dog tetraplegy. (2009) (0)
- Serum homocysteine in levodopa treated Parkinson's disease patients. (2008) (0)
- Scrutinizing disease states and regulation in human microglia (2021) (0)
- Systemic and Local Factors’ Influence on the Topological Differences in Deep Vein Thrombosis (2019) (0)
- Neuronal defects in a human cellular model of 22q11.2 deletion syndrome (2020) (0)
- Ipscs - A Platform To Study Autism Spectrum Disorder (2019) (0)
- Assembling Three‐Dimensional Models of the Human Brain to Study Development and Disease (2020) (0)
- Generation and assembly of human brain region–specific three-dimensional cultures (2018) (0)
- Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures (2019) (0)
- Targeting Cell Death Mechanism Specifically in Triple Negative Breast Cancer Cell Lines (2022) (0)
- The effect of exosomes in transferring TET signaling alterations (2022) (0)
- A framework for the investigation of rare genetic disorders in neuropsychiatry (2019) (0)
- Cytological characteristics in the diagnostic of the cavitary effusions that are associated to the neoplastic processes in carnivore. (2012) (0)
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What Schools Are Affiliated With Sergiu P. Pașca?
Sergiu P. Pașca is affiliated with the following schools:
