Seung-Yong Seong
South Korean immunologist and microbiologist
Seung-Yong Seong's AcademicInfluence.com Rankings

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Biology
Seung-Yong Seong's Degrees
- Bachelors Microbiology Seoul National University
- Masters Immunology Yonsei University
Why Is Seung-Yong Seong Influential?
(Suggest an Edit or Addition)According to Wikipedia, Seung-Yong Seong is a South Korean immunologist and microbiologist known for his study of innate immune system response and his development of the damage-associated molecular pattern model of immune response initiation in collaboration with Polly Matzinger. Seong is also known for his research on the bacterium Orientia tsutsugamushi and his research on immunological adjuvant when he was a student. Since 2013 he has served as Director of the Wide River Institute of Immunology – Seoul National University in conjunction with his Professor position in the Microbiology and Immunology department of Seoul National University College of Medicine. In 2012, he became Editor in Chief of the World Journal of Immunology.
Seung-Yong Seong's Published Works
Published Works
- Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses (2004) (1145)
- A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy. (2011) (433)
- Orientia tsutsugamushi infection: overview and immune responses. (2001) (250)
- Nanog signaling in cancer promotes stem-like phenotype and immune evasion. (2012) (164)
- Expression of Chemokine Genes in Murine Macrophages Infected with Orientia tsutsugamushi (2000) (84)
- Current status of protein chip development in terms of fabrication and application (2003) (73)
- Induction of homologous immune response to Rickettsia tsutsugamushi Boryong with a partial 56-kilodalton recombinant antigen fused with the maltose-binding protein MBP-Bor56 (1997) (71)
- Cross-Protective Immunity of Mice Induced by Oral Immunization with Pneumococcal Surface Adhesin A Encapsulated in Microspheres (2002) (67)
- High-level expression of a 56-kilodalton protein gene (bor56) of Rickettsia tsutsugamushi Boryong and its application to enzyme-linked immunosorbent assays (1993) (66)
- Novel mucosal immunization with polysaccharide-protein conjugates entrapped in alginate microspheres. (1998) (65)
- Enhancement of dendritic cell-based vaccine potency by anti-apoptotic siRNAs targeting key pro-apoptotic proteins in cytotoxic CD8(+) T cell-mediated cell death. (2009) (65)
- The Ratio of Peripheral Regulatory T Cells to Lox-1+ Polymorphonuclear Myeloid-derived Suppressor Cells Predicts the Early Response to Anti-PD-1 Therapy in Patients with Non-Small Cell Lung Cancer. (2019) (64)
- Microtubule- and Dynein-Mediated Movement ofOrientia tsutsugamushi to the Microtubule Organizing Center (2001) (60)
- Expression of Chemokine Genes in Human Dermal Microvascular Endothelial Cell Lines Infected with Orientia tsutsugamushi (2001) (59)
- Intracellular Invasion by Orientia tsutsugamushi Is Mediated by Integrin Signaling and Actin Cytoskeleton Rearrangements (2010) (58)
- CD14 but not MD2 transmit signals from DAMP. (2010) (56)
- Neutralization epitopes on the antigenic domain II of the Orientia tsutsugamushi 56-kDa protein revealed by monoclonal antibodies. (2000) (55)
- Induction of the Gene Encoding Macrophage Chemoattractant Protein 1 by Orientia tsutsugamushi in Human Endothelial Cells Involves Activation of Transcription Factor Activator Protein 1 (2002) (54)
- The Effects of Climate Change and Globalization on Mosquito Vectors: Evidence from Jeju Island, South Korea on the Potential for Asian Tiger Mosquito (Aedes albopictus) Influxes and Survival from Vietnam Rather Than Japan (2013) (50)
- Rapid diagnosis of scrub typhus by a passive hemagglutination assay using recombinant 56-kilodalton polypeptides (1993) (46)
- Partial role of TLR4 as a receptor responding to damage-associated molecular pattern. (2009) (46)
- Protective Immunity of Microsphere-Based Mucosal Vaccines against Lethal Intranasal Challenge withStreptococcus pneumoniae (1999) (43)
- Anti-inflammatory effects of 8-hydroxydeoxyguanosine in LPS-induced microglia activation: suppression of STAT3-mediated intercellular adhesion molecule-1 expression (2006) (42)
- Induction of neutralizing antibody in mice by immunization with recombinant 56 kDa protein of Orientia tsutsugamushi. (1997) (42)
- Detection and hazard assessment of pathogenic microorganisms in medical wastes (2009) (41)
- Transcriptional Regulation of IFN-λ Genes in Hepatitis C Virus-infected Hepatocytes via IRF-3·IRF-7·NF-κB Complex* (2014) (32)
- Chemokine and cytokine production during Orientia tsutsugamushi infection in mice. (2004) (30)
- Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice (2018) (30)
- Functional manipulation of dendritic cells by photoswitchable generation of intracellular reactive oxygen species. (2015) (28)
- Mapping of antigenic determinant regions of the Bor56 protein of Orientia tsutsugamushi (1997) (28)
- Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation (2008) (28)
- Modification of dendritic cells with interferon‐γ‐inducible protein‐10 gene to enhance vaccine potency (2009) (28)
- Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer (2020) (28)
- Global gene expression profile of Orientia tsutsugamushi (2010) (26)
- GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity (2014) (24)
- Pattern difference of dissociated hand muscle atrophy in amyotrophic lateral sclerosis and variants (2015) (24)
- Cellular invasion of Orientia tsutsugamushi requires initial interaction with cell surface heparan sulfate. (2000) (24)
- Chemokine and Cytokine Production in Susceptible C3H/HeN Mice and Resistant BALB/c Mice during Orientia tsutsugamushi Infection (2005) (24)
- Enhancement of DNA vaccine potency by antigen linkage to IFN‐γ‐inducible protein‐10 (2011) (23)
- Microimmunoassay Using a Protein Chip: Optimizing Conditions for Protein Immobilization (2002) (23)
- Orientia tsutsugamushi Inhibits Apoptosis of Macrophages by Retarding Intracellular Calcium Release (2002) (23)
- Apolipoproteins inhibit the innate immunity activated by necrotic cells or bacterial endotoxin (2009) (21)
- Protective anti‐tumour immune responses by murine dendritic cells pulsed with recombinant Tat‐carcinoembryonic antigen derived from Escherichia coli (2009) (21)
- Down‐Regulation of gp96 by Orientia tsutsugamushi (2004) (19)
- Homotypic and Heterotypic Antibody Responses to a 56-Kilodalton Protein of Orientia tsutsugamushi (1999) (19)
- Molecular and serologic survey of Orientia tsutsugamushi infection among field rodents in southern Cholla Province, Korea. (1998) (18)
- Isolation of a New Orientia tsutsugamushi Serotype (1997) (16)
- The Tat‐conjugated N‐terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1‐expressing tumours (2009) (14)
- Neuroprotective Effect of Human Adipose Stem Cell-Derived Extract in Amyotrophic Lateral Sclerosis (2016) (14)
- Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice (2015) (13)
- Effect of Toll-like receptor 2 and 4 of corneal fibroblasts on cytokine expression with co-cultured antigen presenting cells. (2011) (11)
- TLR4-independent and PKR-dependent interleukin 1 receptor antagonist expression upon LPS stimulation. (2009) (11)
- Action of Lipopolysaccharide on Interstitial Cells of Cajal from Mouse Small Intestine (2012) (11)
- Cardiolipin activates antigen‐presenting cells via TLR2‐PI3K‐PKN1‐AKT/p38‐NF‐kB signaling to prime antigen‐specific naïve T cells in mice (2018) (11)
- Proteomic Analysis of Amniotic Fluid Proteins for Predicting the Outcome of Emergency Cerclage in Women with Cervical Insufficiency (2020) (10)
- T-track PCR fingerprinting for the rapid detection of genetic polymorphism. (1997) (10)
- Peroral immunization of microencapsulated human VP8 in combination with cholera toxin induces intestinal antibody responses. (1999) (9)
- Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats (2019) (8)
- Expansion of Myeloid-Derived Suppressor Cells Correlates with Renal Progression in Type 2 Diabetic Nephropathy (2020) (8)
- A Missed Proteome in Living Organisms: A Hyppo System (2006) (5)
- Pattern of Respiratory Deterioration in Sporadic Amyotrophic Lateral Sclerosis According to Onset Lesion by Using Respiratory Function Tests (2015) (5)
- Editorial: DAMPs Across the Tree of Life (2022) (5)
- Alterations in intracellular Ca2+ levels in human endometrial stromal cells after decidualization. (2019) (5)
- Transcriptional regulation of IFN-λ genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex. (2014) (4)
- Transcriptional regulation of IFN-λ genes in Hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex (2014) (4)
- Differential interleukin-1β induction by uropathogenic Escherichia coli correlates with its phylotype and serum C-reactive protein levels in Korean infants (2019) (3)
- GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease (2022) (3)
- Nonclinical toxicology studies with sodium taurodeoxycholate: acute and subacute toxicity in dogs (2019) (2)
- Cell Death and Immunity (2011) (2)
- Low serum Kallistatin level was associated with poor neurological outcome of out-of-hospital cardiac arrest survivors: Proteomics study. (2018) (2)
- HY209 ameliorates atopic dermatitis through NF-KB and P38 inhibition (2020) (1)
- Infectivity of Orientia tsutsugamushi to Various Eukaryotic Cells and Their Cellular Invasion Mechanism (1999) (1)
- Erratum: Transcriptional regulation of ifn-λ genes in hepatitis c virus-infected hepatocytes via irf-3·irf-7·nf-κb complex (JOURNAL OF BIOLOGICAL CHEMISTRY (2014) 289 (11861)) (2014) (1)
- Cationic lipid emulsion; A novel, non-viral, and non-liposomal gene delivery system (1997) (1)
- Role of inflammasomes in neuroinflammation after ischemic stroke (2021) (1)
- RapidDiagnosis ofScrubTyphusbya Passive Hemagglutination AssayUsingRecombinant 56-Kilodalton Polypeptides (1993) (0)
- Taurodeoxycholate, a master key locking both priming and activation signal necessary for inflammasomal activation of microglia by Amyloid beta in Alzheimer’s diseases (2020) (0)
- Identifying microRNAs involved in vestibular compensation using vestibular nucleus of the rat (2008) (0)
- A multicenter, randomized, double-blind, placebo-controlled phase ii trial of intravenous inflammasome inhibitor (NuSepin) for the treatment of COVID-19 patients (2021) (0)
- GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity (2014) (0)
- HY209 alleviates inflammation in colitis mice through NLRP3 inflammasome inhibition (2020) (0)
- Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer (2020) (0)
- Detection of Salmonella genes in stool samples of children aged 5 years and younger in urban and rural areas of Bangladesh. (2021) (0)
- Improved survival in experimental sepsis with conjugated cholic acids preventing activation of dendritic cells by LPS (134.48) (2009) (0)
- CD115− monocytic myeloid-derived suppressor cells are precursors of OLFM4high polymorphonuclear myeloid-derived suppressor cells (2023) (0)
- The Effect of TLR4 on the Survival of MHC Mismatched Corneal Allograft (2008) (0)
- 310: CHANGES IN SERUM PROTEOME PROFILES AND NEUROLOGIC OUTCOME OF CARDIAC ARREST SURVIVORS (2018) (0)
- Recombinant rotavirus outer capsid protein a subunit vaccine (1998) (0)
- Orientia tsutsugamushi Lines Infected with Dermal Microvascular Endothelial Cell Expression of Chemokine Genes in Human (2001) (0)
- Non-classical anti-inflammatory drugs (NCAIDs) ameliorates brain inflammation and improves memory in Alzheimer’s diseases mice model (2022) (0)
- Mucosal immune responses induced by a recombinant pneumococcal surface adhesin A protein encapsulated in alginate microspheres (1999) (0)
- Neuroprotective Effect of Human Adipose Stem Cell-Derived Extract in Amyotrophic Lateral Sclerosis (2015) (0)
- , tsutsugamushi Orientia Macrophages Infected with Expression of Chemokine Genes in Murine (1999) (0)
- IMMUNE RESPONSE TO TSUTSUGAMUSHI DISEASE (1999) (0)
- Taurodeoxycholate, a GPCR19 agonist, ameliorates atopic dermatitis in Balb/c mice. (2023) (0)
- Front & Back Matter (2012) (0)
- 47 kDa Protein of Orientia tsutsugamushi Do a Critical Role in Invasion to Eucaryotic Cells by Binding to Cell Surface Heparan Sulfate (2000) (0)
- A multicenter, randomized, double-blind, placebo- controlled phase ii trial of intravenous in ammasome inhibitor (NuSepin) for the treatment of COVID-19 patients (2021) (0)
- Neuroprotective effect of alpha-kinase 1 knockdown against cerebral ischemia through inhibition of the NF-κB pathway and neuroinflammation. (2022) (0)
- GPCR19 regulates P2X7R-mediated NLRP3 inflammasomal activation of microglia by Amyloid β in Alzheimer’s diseases (2020) (0)
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