Shankar Balasubramanian
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Shankar Balasubramanianchemistry Degrees
Chemistry
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Historical Rank
Organic Chemistry
#328
World Rank
#394
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Chemistry
Why Is Shankar Balasubramanian Influential?
(Suggest an Edit or Addition)Shankar Balasubramanian's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Accurate Whole Human Genome Sequencing using Reversible Terminator Chemistry (2008) (3580)
- Quantitative visualization of DNA G-quadruplex structures in human cells. (2013) (1582)
- Prevalence of quadruplexes in the human genome (2005) (1419)
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? (2011) (1344)
- G-quadruplexes in promoters throughout the human genome (2006) (1075)
- Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution (2012) (829)
- High-throughput sequencing of DNA G-quadruplex structures in the human genome (2015) (774)
- DNA sequencing at 40: past, present and future (2017) (645)
- An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation. (2007) (636)
- Small molecule-induced DNA damage identifies alternative DNA structures in human genes (2012) (533)
- G-quadruplex structures mark human regulatory chromatin (2016) (522)
- 5′-UTR RNA G-quadruplexes: translation regulation and targeting (2012) (522)
- Putative DNA quadruplex formation within the human c-kit oncogene. (2005) (489)
- G-quadruplex nucleic acids as therapeutic targets. (2009) (485)
- Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. (2014) (459)
- 5-Hydroxymethylcytosine is a predominantly stable DNA modification. (2014) (421)
- DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential (2017) (417)
- The regulation and functions of DNA and RNA G-quadruplexes (2020) (410)
- Loop-length-dependent folding of G-quadruplexes. (2004) (402)
- A proton-fuelled DNA nanomachine. (2003) (391)
- G-Quadruplex structures are stable and detectable in human genomic DNA (2013) (387)
- Micromachine-enabled capture and isolation of cancer cells in complex media. (2011) (372)
- A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. (2006) (367)
- G-quadruplexes: the beginning and end of UTRs (2008) (367)
- A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres. (2008) (356)
- CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours (2017) (335)
- Quadruplex nucleic acids. (2006) (328)
- Existence and consequences of G-quadruplex structures in DNA. (2014) (306)
- The Structure and Function of DNA G-Quadruplexes (2020) (303)
- A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation (2013) (291)
- Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine (2013) (287)
- LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans (2009) (263)
- rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome (2016) (263)
- A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. (2008) (261)
- Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer (2003) (257)
- Motion-based DNA detection using catalytic nanomotors. (2010) (253)
- Chemical sensing based on catalytic nanomotors: motion-based detection of trace silver. (2009) (235)
- Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. (2007) (229)
- Rapid delivery of drug carriers propelled and navigated by catalytic nanoshuttles. (2010) (227)
- Lytic phage as a specific and selective probe for detection of Staphylococcus aureus--A surface plasmon resonance spectroscopic study. (2007) (225)
- FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts* (2008) (225)
- 5-Formylcytosine can be a stable DNA modification in mammals. (2015) (218)
- Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase (2012) (216)
- The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. (2011) (215)
- G-quadruplexes regulate Epstein-Barr virus-encoded nuclear antigen 1 mRNA translation. (2014) (202)
- METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation (2019) (202)
- Whole genome experimental maps of DNA G-quadruplexes in multiple species (2019) (195)
- Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution. (2014) (192)
- DNA molecular motor driven micromechanical cantilever arrays. (2005) (187)
- Functionalized micromachines for selective and rapid isolation of nucleic acid targets from complex samples. (2011) (187)
- A reversible pH-driven DNA nanoswitch array. (2006) (185)
- A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. (2011) (185)
- Strong antimicrobial coatings: single-walled carbon nanotubes armored with biopolymers. (2008) (179)
- FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA (2011) (177)
- A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. (2009) (177)
- Template-assisted fabrication of salt-independent catalytic tubular microengines. (2010) (176)
- Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies (2015) (172)
- Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity. (1994) (170)
- Small-molecule-mediated G-quadruplex isolation from human cells. (2010) (163)
- Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36 (2018) (162)
- Suppression of the FOXM1 transcriptional program via novel small molecule inhibition (2014) (155)
- Binding Interactions between Long Noncoding RNA HOTAIR and PRC2 Proteins (2013) (154)
- Single-molecule visualisation of DNA G-quadruplex formation in live cells (2020) (150)
- A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro (2011) (146)
- Non-Arrhenius kinetics for the loop closure of a DNA hairpin (2001) (144)
- Ultrasensitive coincidence fluorescence detection of single DNA molecules. (2003) (144)
- Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. (2007) (141)
- Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues (2014) (141)
- The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. (2010) (137)
- Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes. (2008) (135)
- G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells. (2011) (134)
- 5-Formylcytosine alters the structure of the DNA double helix (2014) (132)
- Formation and Abundance of 5-Hydroxymethylcytosine in RNA (2015) (128)
- Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms (2016) (128)
- Selective RNAVersus DNA G-Quadruplex Targeting by In Situ Click Chemistry** (2012) (126)
- Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing (2018) (125)
- Enhanced stability of enzyme organophosphate hydrolase interfaced on the carbon nanotubes. (2010) (125)
- The kinetics and folding pathways of intramolecular G-quadruplex nucleic acids. (2012) (122)
- Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing (2019) (121)
- DNA G-quadruplex structures mould the DNA methylome (2018) (117)
- An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2 (2012) (115)
- Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells (2013) (115)
- G-Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells (2013) (114)
- Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae (2011) (113)
- Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. (2007) (112)
- A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression. (2009) (110)
- Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands. (2006) (110)
- Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands. (2006) (109)
- Propulsion of nanowire diodes. (2010) (109)
- Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction. (2007) (108)
- Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells† †Electronic supplementary information (ESI) available: Experimental procedures and characterization of building blocks and pyridostatin analogues and FRET-melting profiles. See DOI: 10.1039/c2o (2012) (107)
- Optically Biased Diffusion of Single Molecules Studied by Confocal Fluorescence Microscopy (1998) (106)
- A sequence-independent analysis of the loop length dependence of intramolecular RNA G-quadruplex stability and topology. (2011) (105)
- Development of a surface plasmon resonance biosensor for the identification of Campylobacter jejuni. (2006) (105)
- Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex. (2010) (103)
- Chemically triggered swarming of gold microparticles. (2011) (101)
- Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells (2014) (100)
- Chemical Methods for Decoding Cytosine Modifications in DNA (2014) (99)
- Stimuli-responsive magnetic nanomicelles as multifunctional heat and cargo delivery vehicles. (2013) (99)
- Thermal modulation of nanomotor movement. (2009) (93)
- Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene. (2008) (93)
- Formation of an interlocked quadruplex dimer by d(GGGT). (2004) (89)
- Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts (2018) (89)
- DSBCapture: in situ capture and direct sequencing of dsDNA breaks (2016) (89)
- oxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips (2015) (87)
- Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry. (2008) (85)
- Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule (2018) (85)
- Machine learning model for sequence-driven DNA G-quadruplex formation (2017) (82)
- Kinetics of unfolding the human telomeric DNA quadruplex using a PNA trap. (2003) (82)
- RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2018) (81)
- Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase (2015) (80)
- Structural Analysis using SHALiPE to Reveal RNA G‐Quadruplex Formation in Human Precursor MicroRNA (2016) (78)
- Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome. (2018) (75)
- Local epigenetic reprogramming induced by G-quadruplex ligands. (2017) (74)
- Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression (2009) (73)
- Electrochemically-triggered motion of catalytic nanomotors. (2009) (73)
- An RNA Hairpin to G-Quadruplex Conformational Transition (2012) (72)
- Synthesis and hybridization analysis of a small library of peptide- oligonucleotide conjugates (1998) (71)
- Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection. (2006) (70)
- Early detection of cancer (2022) (70)
- Targeted Detection of G-Quadruplexes in Cellular RNAs** (2015) (68)
- Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition. (2008) (68)
- Landscape of G-quadruplex DNA structural regions in breast cancer (2020) (68)
- G-quadruplex recognition by bis-indole carboxamides. (2008) (65)
- G-quadruplexes are transcription factor binding hubs in human chromatin (2021) (65)
- Mapping and elucidating the function of modified bases in DNA (2017) (63)
- Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines. (2010) (62)
- In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine (2016) (62)
- Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry. (2004) (61)
- G-quadruplex ligands exhibit differential G-tetrad selectivity. (2015) (61)
- 5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells (2018) (60)
- Dynamic covalent chemistry on self-templating peptides: formation of a disulfide-linked beta-hairpin mimic. (2003) (59)
- Single-molecule analysis of human telomerase monomer. (2008) (59)
- High-performance bioassisted nanophotocatalyst for hydrogen production. (2013) (59)
- Reprogramming the Mechanism of Action of Chlorambucil by Coupling to a G-Quadruplex Ligand (2014) (58)
- Genetic interactions of G-quadruplexes in humans (2019) (58)
- Synthesis and binding studies of novel diethynyl-pyridine amides with genomic promoter DNA G-quadruplexes. (2011) (57)
- Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation. (2001) (56)
- Selective recognition of a DNA G-quadruplex by an engineered antibody. (2008) (55)
- Highly sensitive phage-based biosensor for the detection of β-galactosidase (2007) (54)
- A PNA4 quadruplex. (2004) (52)
- G-quadruplex structures within the 3′ UTR of LINE-1 elements stimulate retrotransposition (2017) (51)
- Accurate Measurement of 5-Methylcytosine and 5-Hydroxymethylcytosine in Human Cerebellum DNA by Oxidative Bisulfite on an Array (OxBS-Array) (2015) (51)
- Synthesis of 2-Oxindole Derivatives via the Intramolecular Heck Reaction on Solid Support (1997) (51)
- G-quadruplex-specific peptide-hemicyanine ligands by partial combinatorial selection. (2003) (51)
- Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming (2017) (51)
- Distinct functions of maternal and somatic Pat1 protein paralogs. (2010) (50)
- Solid phase synthesis - designer linkers for combinatorial chemistry : a review (1999) (50)
- G-quadruplexes in promoters throughout the human genome (2007) (50)
- The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis (1997) (49)
- Experimental approaches to identify cellular G-quadruplex structures and functions (2012) (48)
- Enzyme-encapsulated silica monolayers for rapid functionalization of a gold surface. (2007) (48)
- FOXM1 binds directly to non-consensus sequences in the human genome (2015) (48)
- Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates. (2009) (47)
- A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing. (2011) (47)
- Selective Chemical Labeling of Natural T Modifications in DNA (2015) (46)
- Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes. (2004) (46)
- Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation. (2003) (46)
- NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence (2017) (46)
- Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. (2006) (46)
- Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach. (2005) (46)
- An Acetylene-Bridged 6,8-Purine Dimer as a Fluorescent Switch-On Probe for Parallel G-Quadruplexes** (2012) (44)
- Molecule by molecule direct and quantitative counting of antibody-protein complexes in solution. (2004) (44)
- Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy. (2004) (44)
- G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic (2009) (43)
- Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment. (1998) (43)
- Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania (2017) (43)
- Probing DNA Surface Attachment and Local Environment Using Single Molecule Spectroscopy (2001) (43)
- Electrochemical Desorption of Proteins from Gold Electrode Surface (2006) (43)
- Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro. (2002) (42)
- Targeting a c-MYC G-quadruplex DNA with a fragment library. (2014) (42)
- Solid-phase methods for the synthesis of cyanine dyes. (2005) (42)
- Single-molecule analysis of DNA immobilized on microspheres. (2000) (42)
- Escherichia coli Chorismate Synthase Catalyzes the Conversion of (6S)-6-Fluoro-5-enolpyruvylshikimate-3-phosphate to 6-Fluorochorismate (1995) (41)
- Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy. (2006) (40)
- An Investigation into Solid-Phase Radical Chemistry - Synthesis of Furan Rings (2004) (40)
- Detection, Structure and Function of Modified DNA Bases. (2019) (39)
- Solid phase reductive alkylation of secondary amines (1996) (39)
- Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter (2018) (36)
- Reaction of (6R)-6-fluoroEPSP with recombinant Escherichia coli chorismate synthase generates a stable flavin mononucleotide semiquinone radical (1992) (36)
- Sequencing abasic sites in DNA at single-nucleotide resolution (2019) (36)
- Synthesis of bis-indole carboxamides as G-quadruplex stabilizing and inducing ligands. (2012) (35)
- Chemical profiling of DNA G-quadruplex-interacting proteins in live cells (2021) (35)
- Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein. (2006) (34)
- Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes (2016) (32)
- Investigating a quadruplex-ligand interaction by unfolding kinetics. (2006) (32)
- Single molecule conformational analysis of DNA G-quadruplexes (2008) (32)
- Studies on the Synthesis, Characterisation and Reactivity of Aromatic Diboronic Acids (1997) (31)
- Rigid cyanine dye nucleic acid labels. (2008) (31)
- Sequencing nucleic acids: from chemistry to medicine. (2011) (31)
- Studies on a Dithiane-Protected Benzoin Photolabile Safety Catch Linker for Solid-Phase Synthesis. (1999) (31)
- Targeting RNA–Protein Interactions within the Human Immunodeficiency Virus Type 1 Lifecycle (2013) (30)
- Promoter G-quadruplex folding precedes transcription and is controlled by chromatin (2021) (29)
- Synthesis of a polymer-supported oxazolidine aldehyde for asymmetric chemistry. (2002) (28)
- Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling. (2006) (28)
- Tetrapeptides induce selective recognition for G-quadruplexes when conjugated to a DNA-binding platform. (2004) (28)
- Targeting DNA G-Quadruplexes with Helical Small Molecules (2014) (28)
- An Epigenetics‐Inspired DNA‐Based Data Storage System (2016) (27)
- Observation of an isotope effect in the chorismate synthase reaction (1990) (27)
- Inhibition of human telomerase by PNA-cationic peptide conjugates. (1999) (26)
- Inhibition of chorismate synthase by (6R)- and (6S)-6-fluoro-5-enolpyruvylshikimate 3-phosphate (1991) (26)
- Site-specific cleavage of human telomerase RNA using PNA-neocuproine.Zn(II) derivatives. (2003) (26)
- 2′-O-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA (2017) (25)
- PNA forms an i-motif. (2005) (25)
- Nanomotor-based 'writing' of surface microstructures. (2010) (25)
- Controlled-folding of a small molecule modulates DNA G-quadruplex recognition. (2009) (25)
- Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. (2004) (25)
- Energetics, Kinetics and Dynamics of Quadruplex Folding (2006) (25)
- The Profile and Dynamics of RNA Modifications in Animals (2017) (25)
- SURVEY AND SUMMARY 5 0 -UTR RNA G-quadruplexes: translation regulation and targeting (2012) (25)
- Exploring a Benzyloxyaniline Linker Utilizing Ceric Ammonium Nitrate (CAN) as a Cleavage Reagent: Solid-Phase Synthesis of N-Unsubstituted β-Lactams and Secondary Amides (2001) (24)
- Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy. (2012) (24)
- Solexa sequencing: decoding genomes on a population scale. (2015) (24)
- Solid-phase catch, activate, and release synthesis of cyanine dyes. (2002) (23)
- Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer. (2013) (23)
- Mechanochemical Properties of Individual Human Telomeric RNA (TERRA) G‐Quadruplexes (2013) (23)
- Double fluorescence resonance energy transfer to explore multicomponent binding interactions: a case study of DNA mismatches (2000) (22)
- Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c3cc44737e (2013) (22)
- Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases (2016) (22)
- Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma (2017) (21)
- A Combinatorial Approach to Identifying Protein Tyrosine Phosphatase Substrates from a Phosphotyrosine Peptide Library (1997) (20)
- Natural, modified DNA bases. (2020) (20)
- Single-Molecule Analysis of the Human Telomerase RNA·Dyskerin Interaction and the Effect of Dyskeratosis Congenita Mutations† (2009) (20)
- A simple nanomixer for single-molecule kinetics measurements. (2006) (19)
- DNA Quadruplexes and Gene Regulation (2006) (19)
- Dynamic covalent chemistry on self-templating PNA oligomers: formation of a bimolecular PNA quadruplex. (2005) (19)
- Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal. (2012) (18)
- Nucleotide contributions to the structural integrity and DNA replication initiation activity of noncoding y RNA. (2014) (18)
- Practical synthesis of a dithiane-protected 3',5'-dialkoxybenzoin photolabile safety-catch linker for solid-phase organic synthesis. (2002) (18)
- Sequencing 5‐Hydroxymethyluracil at Single‐Base Resolution (2018) (17)
- Recent developments in linker design and application. (2003) (17)
- G-quadruplex DNA structures in human stem cells and differentiation (2022) (17)
- Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved. (1995) (17)
- Synthesis and biophysical analysis of modified thymine-containing DNA oligonucleotides. (2017) (17)
- An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging. (2019) (17)
- Properties of fluorophores on solid phase resins; implications for screening, encoding and reaction monitoring (1997) (16)
- TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions (2021) (16)
- Observation of a secondary tritium isotope effect in the chorismate synthase reaction. (1995) (16)
- RNA conformation in catalytically active human telomerase. (2010) (16)
- Structural Diversity of G-Quadruplex Scaffolds (2006) (15)
- Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes. (2010) (15)
- Design and synthesis of new bile acid-based macrocycles (1995) (15)
- A convenient synthetic route to oligonucleotide conjugates (1997) (14)
- Charting a course for chemistry (2019) (14)
- Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex** (2014) (13)
- A stereoselective synthesis of 1,3,4-substituted β-lactams from polymer-supported chiral oxazolidine aldehyde (2000) (13)
- Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC. (2008) (13)
- Enhanced cooperative binding of oligonucleotides to form DNA duplexes mediated by metal ion chelation. (2002) (13)
- A Model for Catalytic Oxidation of Hydrocarbons in the Vapor Phase (1975) (13)
- Fluorescence studies of single biomolecules. (2004) (12)
- Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex** (2014) (12)
- Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments (2016) (11)
- Decoding genomes at high speed: implications for science and medicine. (2011) (11)
- Affinity-Selected Bicyclic Peptide G-Quadruplex Ligands Mimic a Protein-like Binding Mechanism (2020) (11)
- From the Combinatorial Chemistry Boom to Polymer-Supported Parallel Chemistry: Established Technologies for Drug Discovery (2004) (11)
- Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library. (2006) (11)
- Highly sensitive phage-based biosensor for the detection of beta-galactosidase. (2007) (10)
- Single-cell mapping of DNA G-quadruplex structures in human cancer cells (2021) (10)
- Synthesis of diastereomerically pure 1,4,5-substituted-2-oxopiperazines on solid-phase (2002) (10)
- Chemical biology on the genome. (2014) (10)
- Solid-phase synthesis of symmetrical 3,6-bispeptide-acridone conjugates. (2002) (9)
- Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma (2020) (9)
- Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis (2020) (9)
- DNA Quadruplex–Ligand Recognition: Structure and Dynamics (2006) (9)
- The regulation and functions of DNA and RNA G-quadruplexes (2020) (9)
- Innentitelbild: Selective RNA Versus DNA G‐Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. 44/2012) (2012) (9)
- Bang-bang shortcut to adiabaticity in trapped-ion quantum simulators (2015) (8)
- Many-body localization landscape (2019) (8)
- Studies on the chemical stability and functional group compatibility of the benzoin photolabile safety-catch linker using an analytical construct. (2002) (8)
- A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation (2019) (8)
- Electrochemical properties of interface formed by interlaced layers of DNA- and lysozyme-coated single-walled carbon nanotubes (2009) (7)
- The synthesis of (6R)-[6-2H]- and (6S)-[6-2H]5-enolpyruvylshikimate-3-phosphate (1991) (7)
- Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences (2020) (7)
- Floquet codes without parent subsystem codes (2022) (6)
- High-resolution sequencing of DNA G-quadruplex secondary structures in the human genome (2015) (6)
- DNA G-quadruplex structures mold the DNA methylome (2018) (6)
- Studies on the chemical stability and synthetic utility of an oxazolidine linker for solid-phase chemistry. (2004) (6)
- Chemical biology of genomic DNA: minimizing PCR bias† (2014) (6)
- Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications (2016) (6)
- Quadruplexes in the Genome (2006) (6)
- Synthesis and Multiple Incorporations of 2′‐O‐Methyl‐5‐hydroxymethylcytidine, 5‐Hydroxymethylcytidine and 5‐Formylcytidine Monomers into RNA Oligonucleotides (2017) (6)
- Individual molecules of dye-labeled DNA act as a reversible two-color switch upon application of an electric field. (2004) (6)
- RNA G-quadruplex structures control ribosomal protein production (2021) (5)
- Recent advances in solid-phase chemical methodologies. (1999) (5)
- Single genome retrieval of context-dependent variability in mutation rates for human germline (2017) (5)
- Strategies for the synthesis of fluorescently labelled PNA. (2000) (5)
- Quadruplex Ligand Recognition: Biological Aspects (2006) (5)
- Exact Time Evolution of the Asymmetric Hubbard Dimer (2016) (5)
- Publisher Correction: DNA sequencing at 40: past, present and future (2019) (4)
- 5-Formylcytosine controls nucleosome positioning through covalent histone-DNA interaction (2017) (4)
- Kinetics of oxidation of pseudocumene in the vapor phase (1974) (4)
- FOXM1 binds directly to non-consensus sequences in the human genome (2015) (4)
- Exploring a chemical encoding strategy for combinatorial synthesis using Friedel-Crafts alkylation. (1999) (4)
- Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase (2012) (4)
- Screening for oligonucleotide binding affinity by a convenient fluorescence competition assay. (1999) (3)
- Unusual Activity of a Chlamydomonas TET/JBP Family Enzyme. (2019) (3)
- Transcriptome-wide profiling of RNA G-quadruplex structures using rG4-seq (2016) (3)
- Solid Phase Synthesis — Designer Linkers for Combinatorial Chemistry (1999) (3)
- Core variability in substitution rates and the basal sequence characteristics of the human genome (2015) (3)
- Recent Developments in Linker Design and Application (2004) (3)
- Tetramethylpyridiniumporphyrazines — A New Class of G‐Quadruplex Inducing and Stabilizing Ligands. (2007) (3)
- Studies on a Dithiane-Protected Benzoin Photolabile Safety Catch Linker for Solid-Phase Synthesis. (1999) (2)
- Sequencing 5-Hydroxymethyluracil at Single-Base Resolution (2018) (2)
- DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody (2022) (2)
- Classical vertex model dualities in a family of two-dimensional frustrated quantum antiferromagnets (2021) (2)
- Exact Quantum Algorithms for Quantum Phase Recognition: Renormalization Group and Error Correction (2022) (2)
- Cover Picture: Micromachine‐Enabled Capture and Isolation of Cancer Cells in Complex Media (Angew. Chem. Int. Ed. 18/2011) (2011) (2)
- Exact wavefunction dualities and phase diagrams of 3D quantum vertex models (2022) (2)
- Titelbild: Micromachine‐Enabled Capture and Isolation of Cancer Cells in Complex Media (Angew. Chem. 18/2011) (2011) (2)
- Addendum: Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution (2014) (2)
- PNA and Oligonucleotide Inhibitors of Human Telomerase (2013) (2)
- RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs (2017) (2)
- Solid phase chemical technologies for combinatorial chemistry (2001) (2)
- DSBCapture: in situ single-nucleotide resolution DNA double-strand break mapping (2016) (1)
- The Biology and Genomic Localization of Cytosine Modifications (2015) (1)
- Identi fi cation of small molecule inhibitors of the Lin 28-mediated blockage of pre-let-7 g processing † (2016) (1)
- A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation (2013) (1)
- G-quadruplexes are transcription factor binding hubs in human chromatin (2021) (1)
- Author response: Genetic interactions of G-quadruplexes in humans (2019) (1)
- Erratum: Mapping and elucidating the function of modified bases in DNA (2017) (1)
- Opto‐epigenetic modulation of DNA methylation with a photo‐responsive small‐molecule approach (2019) (1)
- Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells (2013) (1)
- Promoter G-quadruplex folding precedes transcription and is controlled by chromatin (2021) (1)
- Formylcytosine alters the structure of the DNA double helix 1 2 (2015) (1)
- Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells (2022) (1)
- Abstract 3088: Transcription factor as target: Novel small molecule inhibits FOXM1 DNA binding and oncogenic gene products (2016) (1)
- Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2019) (1)
- Solitons in lattice field theories via tight-binding supersymmetry (2021) (1)
- Self-organization of plasticity and specialization in a primitively social insect (2022) (1)
- Therapeutics: Click and discover (2017) (1)
- In vivo genome-wide profiling reveals a tissue-specific role for 5-formylcytosine (2016) (1)
- Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells (2022) (0)
- Erratum: Targeting the c-kit promoter G-quadruplexes with 6-substituted indenoisoquinolines (ACS Medicinal Chemistry Letters (2010) 1 (306) DOI: 10.1021/ml100062z) (2010) (0)
- Methods for Detection of Cytosine Modification (2012) (0)
- Landscape of G-quadruplex DNA structural regions in breast cancer (2020) (0)
- Dataset for: An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging (2019) (0)
- Genome-wide DNAMethylation Signatures Are Determinedby DNMT3A/B Sequence Preferences (2020) (0)
- Structure of a G-quadruplex (2019) (0)
- Massively parallel synthetic sequencing of DNA on clonal arrays. (2007) (0)
- Directed locomotion of bimetallic synthetic nanomotors (2009) (0)
- Process study of the alkalifusion of 2- aminoanthraquinone to indanthrone (1963) (0)
- Results 0 . 1 Preparation of PCR-free bisulfite libraries (2016) (0)
- Abstract PL04-01: G-quadruplexes and DNA dynamics (2017) (0)
- METTL 1 Promotes let-7 M icroRNA Processing via m 7 G Methylation Graphical Abstract Highlights (2019) (0)
- Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2019) (0)
- Decoding genomes. (2015) (0)
- Single genome retrieval of context-dependent variability in mutation rates for human germline (2017) (0)
- Single-Molecule Analysis of the Human Telomerase RNA center dot Dyskerin Interaction and the Effect of Dyskeratosis Congenita Mutations (2018) (0)
- Erratum: Single-molecule analysis of human telomerase monomer (2008) (0)
- Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases (2016) (0)
- GENE-46. COMPARISON OF MATCHED GLIOBLASTOMA TUMOR AND MARGIN SAMPLES USING SINGLE BASE RESOLUTION MAPS REVEALS ACQUIRED, EARLY EPIGENETIC CHANGES THAT PREDISPOSE TO MUTATIONS DURING TUMOURIGENESIS (2017) (0)
- UNDERSTANDING AND TARGETING PROTEIN-RNA INTERACTIONS WITHIN THE Ψ- PACKAGING DOMAIN OF HIV-1 (2012) (0)
- Theoretical model for Human Telomerase RNA Monomer from FRET measurements. (2006) (0)
- Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2019) (0)
- Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA (2022) (0)
- Sequencing Nucleic Acids: From Chemistry to Medicine (2011) (0)
- All parallel G-quadruplex from the promoter sequence of the c-kit oncogene (2009) (0)
- A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA. (2023) (0)
- G-quadruplex: the DNA quadruple helix (2014) (0)
- An interview with Shankar Balasubramanian. (2013) (0)
- Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania (2017) (0)
- Solid-Phase Chemical Technologies for Combinatorial Chemistry (2002) (0)
- Core variability in mutation rates shape the basal sequence characteristics of the human genome (2015) (0)
- Selective Chemical Functionalization at N6 mdA Residues in DNA (2020) (0)
- G-quadruplex DNA structures in human stem cells and differentiation (2022) (0)
- Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2019) (0)
- Thermodynamic Melting Studies on Oligonucleotide-Peptide Conjugates (1999) (0)
- Chem-map profiles drug binding to chromatin in cells. (2023) (0)
- in the human genome in vitro using purified single-stranded DNA as a template for G4-seq, a 31 high-throughput sequencing method for the discovery of structural features in DNA (2016) (0)
- Wales Andrew Wheatley Paul Wood Peter Wothers Dominic Wright An introduction to Cambridge Chemistry Academic staff (2012) (0)
- University of Groningen Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts Herdy, (2018) (0)
- Concurrent BCL2 / MYC Gene Amplification Associates with Increased DNA G-Quadruplex Formation in DLBCL (2015) (0)
- From DNA to mountain climbing. Shankar Balasubramanian talks to Alison Stoddart about his research and other interests. (2007) (0)
- Correction to Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines (2010) (0)
- Crystal structure of a tetramolecular RNA G-quadruplex in potassium (2015) (0)
- Reduced Bisulfite Sequencing: Quantitative Base-Resolution Sequencing of 5-Formylcytosine. (2021) (0)
- Methods for detecting nukleotidmodificering (2012) (0)
- RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs (2018) (0)
- Studies on the Synthesis, Characterization and Reactivity of Aromatic Diboronic Acids. (1997) (0)
- Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36 (2018) (0)
- Exploring a benzyloxyaniline linker utilizing ceric ammonium nitrate (CAN) as a cleavage reagent: solid-phase synthesis of N-unsubstituted beta-lactams and secondary amides. (2001) (0)
- Inside Cover: Selective RNA Versus DNA G‐Quadruplex Targeting by In Situ Click Chemistry (Angew. Chem. Int. Ed. 44/2012) (2012) (0)
- Synthesis of Responsive Polymer Brushes on Magnetic Nanoparticles (2013) (0)
- Machine learning model for sequence-driven DNA G-quadruplex formation (2017) (0)
- Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis. (2023) (0)
- Analytical Methods For Vapor-Phase Oxidation-Products Of Pseudocumene (1973) (0)
- DNA promoter sequence of the c-kit oncogene forms a parallel G-quadruplex (c-kit2) with a long loop that confers asymmetric internal dynamics in the G-tetrads (2009) (0)
- Progress in Chemical Encoding for Combinatorial Synthesis (1999) (0)
- NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence (2018) (0)
- Base resolution maps reveal the importance of 5-hydroxymethylcytosine in a human glioblastoma (2017) (0)
- 823 Transcriptional down-regulation of the androgen receptor by promoter G-quadruplex stabilisation; a potential alternative treatment in castrate-resistant prostate cancer (2013) (0)
- Crystal structure of an oligonucleotide containing 5-formylcytosine (2014) (0)
- Figures RNA G-quadruplexes at upstream open reading frames cause DHX 36-and DHX 9-dependent translation of human mRNAs (2018) (0)
- A Spontaneous Ring‐Opening Reaction Leads to a Repair‐Resistant Thymine Oxidation Product in Genomic DNA (2019) (0)
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