Sharon Gerecht
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Israeli biomedical engineer
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Sharon Gerechtengineering Degrees
Engineering
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#5223
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Biomedical Engineering
#576
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#586
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Applied Physics
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#2988
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Engineering
Sharon Gerecht's Degrees
- PhD Biomedical Engineering Technion – Israel Institute of Technology
- Masters Biomedical Engineering Technion – Israel Institute of Technology
- Bachelors Biomedical Engineering Technion – Israel Institute of Technology
Why Is Sharon Gerecht Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sharon Gerecht is an Israeli American bioengineer. She is a professor of chemical and biomolecular engineering at the Whiting School of Engineering. Gerecht is the Kent Gordon Croft Investment Management Faculty scholar and director of the Johns Hopkins Institute of NanoBioTechnology . She holds a joint appointment in Oncology at the Johns Hopkins School of Medicine and in Materials Science and Engineering and Biomedical Engineering. She will be moving to Duke University in 2022. In 2011, she won a National Science Foundation CAREER Award. She was elected a fellow of the American Institute for Medical and Biological Engineering in 2016 and a member of the National Academy of Medicine in 2019. Gerecht completed a B.A. in biology at Technion – Israel Institute of Technology in 1994. She earned a M.Sc. in medical sciences at Tel Aviv University in 1999 and a Ph.D. in biotechnology engineering at Technion in 2004. She was a postdoctoral researcher at Massachusetts Institute of Technology.
Sharon Gerecht's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells (2007) (640)
- Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing (2011) (425)
- Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells. (2007) (281)
- Vascular Progenitor Cells Isolated From Human Embryonic Stem Cells Give Rise to Endothelial and Smooth Muscle–Like Cells and Form Vascular Networks In Vivo (2007) (248)
- Electrical stimulation of human embryonic stem cells: cardiac differentiation and the generation of reactive oxygen species. (2009) (246)
- The effect of actin disrupting agents on contact guidance of human embryonic stem cells. (2007) (214)
- Micro-bioreactor array for controlling cellular microenvironments. (2007) (214)
- Human embryonic stem cell transplantation to repair the infarcted myocardium (2007) (201)
- Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix (2013) (180)
- Biomimetic approach to cardiac tissue engineering (2007) (176)
- Enhancement of In Vitro Capillary Tube Formation by Substrate Nanotopography (2008) (170)
- Controlled activation of morphogenesis to generate a functional human microvasculature in a synthetic matrix. (2011) (164)
- A physical sciences network characterization of non-tumorigenic and metastatic cells (2013) (157)
- Functional neovascularization of biodegradable dextran hydrogels with multiple angiogenic growth factors. (2011) (151)
- To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies. (2016) (138)
- Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells (2009) (135)
- Hypoxia-Inducible Hydrogels (2014) (135)
- Engineered Biopolymeric Scaffolds for Chronic Wound Healing (2016) (134)
- Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. (2013) (127)
- Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells. (2013) (122)
- Hydrogels to model 3D in vitro microenvironment of tumor vascularization. (2014) (121)
- Review: in vitro microvessel models. (2015) (120)
- Spatial control of cell-mediated degradation to regulate vasculogenesis and angiogenesis in hyaluronan hydrogels. (2012) (117)
- A porous photocurable elastomer for cell encapsulation and culture. (2007) (103)
- Acellular and cellular approaches to improve diabetic wound healing. (2019) (99)
- Human Brain Microvascular Endothelial Cells Derived from the BC1 iPS Cell Line Exhibit a Blood-Brain Barrier Phenotype (2016) (98)
- Adaptation to oxygen deprivation in cultures of human pluripotent stem cells, endothelial progenitor cells, and umbilical vein endothelial cells. (2010) (94)
- Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis (2015) (87)
- Engineered human vascularized constructs accelerate diabetic wound healing. (2016) (85)
- Creating polymer hydrogel microfibres with internal alignment via electrical and mechanical stretching. (2014) (84)
- Intratumoral oxygen gradients mediate sarcoma cell invasion (2016) (82)
- Reconstructing the differentiation niche of embryonic stem cells using biomaterials. (2011) (79)
- Smooth-Muscle-Like Cells Derived from Human Embryonic Stem Cells Support and Augment Cord-Like Structures In Vitro (2010) (79)
- Endothelial cell responses to micropillar substrates of varying dimensions and stiffness. (2012) (78)
- Perivascular cells in blood vessel regeneration (2013) (76)
- Vascular tissue engineering: biodegradable scaffold platforms to promote angiogenesis (2013) (72)
- Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells (2009) (71)
- The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells (2012) (70)
- Functional groups affect physical and biological properties of dextran-based hydrogels. (2009) (69)
- Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting. (2014) (69)
- Harnessing developmental processes for vascular engineering and regeneration (2014) (66)
- Biomechanical strain induces elastin and collagen production in human pluripotent stem cell-derived vascular smooth muscle cells. (2015) (66)
- Hypoxia and free radicals: role in tumor progression and the use of engineering-based platforms to address these relationships. (2015) (65)
- Acellular hydrogel for regenerative burn wound healing: translation from a porcine model (2015) (65)
- Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments (2012) (65)
- Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy (2019) (64)
- Fibronectin Deposition Participates in Extracellular Matrix Assembly and Vascular Morphogenesis (2016) (63)
- Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease (2014) (62)
- A self-healing hydrogel as an injectable instructive carrier for cellular morphogenesis. (2018) (61)
- Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D (2019) (60)
- Three-Dimensional Vascular Network Assembly From Diabetic Patient-Derived Induced Pluripotent Stem Cells (2015) (60)
- Going with the flow: microfluidic platforms in vascular tissue engineering. (2014) (59)
- Guiding endothelial progenitor cell tube formation using patterned fibronectin surfaces (2010) (54)
- Vascular engineering using human embryonic stem cells (2009) (53)
- Bioinspired Hydrogels to Engineer Cancer Microenvironments. (2017) (52)
- Enhanced elastin synthesis and maturation in human vascular smooth muscle tissue derived from induced-pluripotent stem cells. (2017) (50)
- Breast cancer cell-derived matrix supports vascular morphogenesis. (2012) (49)
- Hyaluronic Acid hydrogels support cord-like structures from endothelial colony-forming cells. (2011) (49)
- The Differential Formation of the LINC-Mediated Perinuclear Actin Cap in Pluripotent and Somatic Cells (2012) (49)
- Unforeseen decreases in dissolved oxygen levels affect tube formation kinetics in collagen gels. (2011) (47)
- Patterning microscale extracellular matrices to study endothelial and cancer cell interactions in vitro. (2012) (46)
- Efficient and Scalable Expansion of Human Pluripotent Stem Cells Under Clinically Compliant Settings: A View in 2013 (2014) (45)
- Engineering the human blood-brain barrier in vitro (2017) (44)
- Hydrogel Network Dynamics Regulate Vascular Morphogenesis (2020) (44)
- Low Oxygen Tension Enhances Endothelial Fate of Human Pluripotent Stem Cells (2014) (44)
- Practical aspects of cardiac tissue engineering with electrical stimulation. (2007) (42)
- Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing (2013) (40)
- Regenerative and durable small-diameter graft as an arterial conduit (2019) (39)
- Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells. (2010) (38)
- Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis (2019) (38)
- The design of dextran-based hypoxia-inducible hydrogels via in situ oxygen-consuming reaction. (2014) (37)
- Compliant substratum guides endothelial commitment from human pluripotent stem cells (2017) (37)
- Fabrication of 3‐dimensional multicellular microvascular structures (2015) (37)
- Engineering blood vessels using stem cells: innovative approaches to treat vascular disorders (2010) (35)
- Functional surfaces for high-resolution analysis of cancer cell interactions on exogenous hyaluronic acid. (2010) (34)
- Capillary Network‐Like Organization of Endothelial Cells in PEGDA Scaffolds Encoded with Angiogenic Signals via Triple Helical Hybridization (2014) (34)
- O2-controllable hydrogels for studying cellular responses to hypoxic gradients in three dimensions in vitro and in vivo (2017) (33)
- Collagen fiber structure guides 3D motility of cytotoxic T lymphocytes. (2020) (32)
- Microbioreactors to manipulate oxygen tension and shear stress in the microenvironment of vascular stem and progenitor cells (2012) (32)
- Engineered microenvironments for human stem cells. (2008) (32)
- A Novel In Vitro Model for Microvasculature Reveals Regulation of Circumferential ECM Organization by Curvature (2013) (32)
- Acellular implantable and injectable hydrogels for vascular regeneration (2015) (30)
- Three-dimensional culture of small-diameter vascular grafts. (2016) (29)
- Hydrogel vehicles for sequential delivery of protein drugs to promote vascular regeneration. (2019) (28)
- Defining Differences among Perivascular Cells Derived from Human Pluripotent Stem Cells (2014) (28)
- Defining Differences among Perivascular Cells Derived from Human Pluripotent Stem Cells (2014) (27)
- Engineering approaches for investigating tumor angiogenesis: exploiting the role of the extracellular matrix. (2012) (26)
- Dual Cross‐Linked Biofunctional and Self‐Healing Networks to Generate User‐Defined Modular Gradient Hydrogel Constructs (2017) (26)
- Stochasticity and Spatial Interaction Govern Stem Cell Differentiation Dynamics (2015) (26)
- Cytoskeletal tension regulates mesodermal spatial organization and subsequent vascular fate (2018) (25)
- Sex differences in the mitochondrial bioenergetics of astrocytes but not microglia at a physiologically relevant brain oxygen tension (2017) (24)
- Characterizing human pluripotent-stem-cell-derived vascular cells for tissue engineering applications. (2015) (24)
- Endothelial progenitor cell recruitment in a microfluidic vascular model (2015) (22)
- Micropattern size‐dependent endothelial differentiation from a human induced pluripotent stem cell line (2017) (22)
- Designer Hydrogels for Precision Control of Oxygen Tension and Mechanical Properties. (2015) (22)
- iPSC-derived endothelial cell response to hypoxia via SDF1a/CXCR4 axis facilitates incorporation to revascularize ischemic retina. (2020) (21)
- Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells. (2018) (21)
- Early Vascular Cells Improve Microvascularization within 3D Cardiac Spheroids. (2019) (21)
- Stem cells and scaffolds for vascularizing engineered tissue constructs. (2009) (20)
- Vascular regeneration: engineering the stem cell microenvironment. (2009) (20)
- The next generation of endothelial differentiation: Tissue-specific ECs. (2021) (19)
- Collagen Fiber Architecture Regulates Hypoxic Sarcoma Cell Migration. (2017) (18)
- A Feedback Loop between Hypoxia and Matrix Stress Relaxation Increases Oxygen-Axis Migration and Metastasis in Sarcoma. (2019) (18)
- Hypoxia Affects the Structure of Breast Cancer Cell-Derived Matrix to Support Angiogenic Responses of Endothelial Cells (2013) (18)
- Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes. (2019) (17)
- Polymeric hydrogels as artificial extracellular microenvironments for cancer research (2015) (17)
- Derivation and network formation of vascular cells from human pluripotent stem cells. (2014) (15)
- Stem cell-derived vasculature: A potent and multidimensional technology for basic research, disease modeling, and tissue engineering. (2016) (14)
- Preview. Mending the failing heart with a vascularized cardiac patch. (2009) (13)
- Micropatterned surfaces to study hyaluronic acid interactions with cancer cells. (2010) (12)
- Recent progress in the use of induced pluripotent stem cells in vascular regeneration (2013) (12)
- RECAPITULATING THE VASCULAR MICROENVIRONMENT IN MICROFLUIDIC PLATFORMS (2013) (11)
- Microfluidics and biomaterials to study angiogenesis (2016) (11)
- Derivation of Endothelial Cells and Pericytes from Human Pluripotent Stem Cells. (2016) (11)
- Vascular Development and Morphogenesis in Biomaterials (2014) (10)
- Human Pluripotent Stem Cells to Engineer Blood Vessels. (2018) (9)
- HIF2A gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics (2020) (9)
- Reconstructing the Vascular Developmental Milieu In Vitro. (2019) (9)
- Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds. (2010) (9)
- Microfluidic platform for the real time measurement and observation of endothelial barrier function under shear stress. (2018) (8)
- Biophysical regulation of vascular differentiation and assembly (2011) (8)
- Development of a biodegradable, temperature-sensitive dextran-based polymer as a cell-detaching substrate. (2012) (8)
- Evolutionarily conserved sequence motif analysis guides development of chemically defined hydrogels for therapeutic vascularization (2020) (7)
- Pericytes Derived from Human Pluripotent Stem Cells. (2018) (7)
- Senescent Cells with Augmented Cytokine Production for Microvascular Bioengineering and Tissue Repairs (2019) (6)
- Extracellular Matrix Regulation of Stem Cell Fate (2018) (6)
- Scalable Production of Human Erythrocytes from Induced Pluripotent Stem Cells (2016) (5)
- Diffusing Colloidal Probes of kT-Scale Biomaterial-Cell Interactions. (2016) (5)
- Bridging the gap: induced pluripotent stem cell derived endothelial cells for 3D vascular assembly (2017) (5)
- Physical Sciences and Engineering Advances in Life Sciences and Oncology (2016) (5)
- Discretizing Three‐Dimensional Oxygen Gradients to Modulate and Investigate Cellular Processes (2021) (4)
- Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. (2022) (4)
- Micropatterned Surfaces for the Study of Cancer and Endothelial Cell Interactions with Hyaluronic Acid (2013) (4)
- Evolutionarily conserved sequence motif analysis guides development of chemically defined hydrogels for therapeutic vascularization. (2020) (4)
- Immunotherapy: Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy (Adv. Mater. 23/2019) (2019) (4)
- Differential HDAC 6 Activit y Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells Graphical (2018) (4)
- The Integrated Role of Biomaterials and Stem Cells in Vascular Regeneration (2010) (4)
- Stem Cell Fate Is a Touchy Subject. (2016) (3)
- Let's get physical: Biomechanical influences on human pluripotent stem cell differentiation towards vascular engineering (2018) (3)
- Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells. (2018) (3)
- Stiffening Matrix Induces Age‐Mediated Microvascular Phenotype Through Increased Cell Contractility and Destabilization of Adherens Junctions (2022) (3)
- Hypoxia‐induced blood‐brain barrier dysfunction is prevented by pericyte‐conditioned media via attenuated actomyosin contractility and claudin‐5 stabilization (2022) (2)
- Biomaterials Approaches in Vascular Engineering: a Review of Past and Future Trends (2011) (2)
- Engineering Niches for Blood Vessel Regeneration (2017) (2)
- Derivation of endothelial cells from pluripotent stem cells in a feeder‐free, two‐dimensional niche (2011) (2)
- Transfusion-transmitted virus in liver-transplanted children. (2001) (2)
- Off-the-Shelf, Heparinized Small Diameter Vascular Graft Limits Acute Thrombogenicity in a Porcine Model. (2022) (2)
- Fast and furious: the mass and motion of stem cells. (2013) (2)
- Cell–biomaterial interactions for blood vessel formation (2014) (1)
- Human embryonic stem cell transplantation to repair the infarcted myocardium. Editorial (2007) (1)
- Mimicking the Microenvironment (2016) (1)
- Abstract B61: Intratumoral oxygen gradients mediate sarcoma cell invasion (2017) (1)
- Integrin binding: Sticking around vessels. (2017) (1)
- Tissue Engineering Approaches to Uncover Therapeutic Targets for Endothelial Dysfunction in Pathological Microenvironments (2022) (1)
- Chapter 51 – Human Vascular Progenitor Cells (2013) (1)
- Chipping Away at Blood-Brain-Barrier Modeling. (2019) (1)
- Engineering Smooth Muscle to Understand Extracellular Matrix Remodeling and Vascular Disease (2022) (1)
- Abstract 5477: Hydrogels to study ECM-oxygen gradient interactions for sarcoma cell migration (2017) (1)
- THREE-DIMENSIONAL CULTURE OF HUMAN EMBRYONIC STEM CELLS (2007) (1)
- Artificial hypoxic microenvironments for vascular tissue regeneration (2015) (0)
- Modeling metastasis: engineering approaches to study the metastatic cascade (2020) (0)
- Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments (2011) (0)
- Engineering bioactive scaffolds for stem cell vascular therapy (2010) (0)
- Fibronectin Participates in Matrix Assembly and Vascular Morphogenesis (2014) (0)
- Vascular Phenotype is Compromised in Dynamically Stiffening Hydrogel (2020) (0)
- Editorial overview: Biological engineering: engineering systems for cancer modeling, diagnostics and therapeutics (2016) (0)
- Topical: 3D Tissue Chips for Space Biology Studies (2021) (0)
- Vascular stiffening in aging females with a hypertension‐induced HIF2A gain‐of‐function mutation (2022) (0)
- microvasculature in a synthetic matrix Controlled activation of morphogenesis to generate a functional human (2011) (0)
- Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration (2022) (0)
- Stem Cells for Vascular Regeneration: An Engineering Approach (2011) (0)
- acLDL acetylated low-density lipoprotein DO dissolved oxygen DPI diphenyleneiodonium EC endothelial cell EVC early vascular cell hiPSCs human-induced pluripotent stem cells hPSCs human pluripotent stem cells OUR oxygen uptake rate PDGFR β platelet-derived growth factor β ROS reactive oxygen species (0)
- Engineering of the microenvironment to accelerate vascular regeneration. (2022) (0)
- Editorial overview: Biological engineering: Stem cell engineering (2017) (0)
- Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration (2022) (0)
- Abstract 960: Deregulation of the Hippo pathway in soft tissue sarcoma promotes FOXM1 expression and tumorigenesis (2015) (0)
- Research highlights. (2011) (0)
- Mechanotransduction of Cardiovascular Development and Regeneration (2020) (0)
- If You Build It, They Will Come: Towards Self-Assembly of Functional Cardiovascular Tissues. (2020) (0)
- Hypoxia and Matrix Manipulation for Vascular Engineering (2011) (0)
- The derivation and maturation of vascular smooth muscle cells from human pluripotent stem cells (2011) (0)
- Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D (2019) (0)
- Manipulating the microenvironment for vascular differentiation and regeneration (2009) (0)
- Reconstructing the ageing extracellular matrix (2023) (0)
- Angiogenesis from endothelial progenitor cells is co‐regulated by vascular endothelial growth factor and matrix stiffness. (2009) (0)
- Abstract 362: Fibronectin facilitates extracellular matrix assembly and vascular morphogenesis . (2013) (0)
- Editorial overview: Biological engineering: complex biological barriers: Transport mechanisms of diverse payloads across complex biological barriers (2021) (0)
- Extracellular Matrix Regulation of Stem Cell Fate (2018) (0)
- Tissue Engineering: Senescent Cells with Augmented Cytokine Production for Microvascular Bioengineering and Tissue Repairs (Adv. Biosys. 8/2019) (2019) (0)
- Abstract 5423: Adaptation to Oxygen Deprivation in Human Pluripotent Stem Cells, Endothelial Progenitors, and Endothelial Cells (2009) (0)
- P18 - ANGIOGENESIS BIOMIMETIC: EXTRACELLULAR MATRIX AND OXYGEN (2013) (0)
- Nanoparticle-based modulation of CD4+ T cell effector and helper functions enhances adoptive immunotherapy (2022) (0)
- BEYOND THE ENDOTHELIUM: THE ROLE OF MURAL CELLS IN VASCULAR BIOLOGY: In vitro systems to study endothelial/pericyte cell interactions (2023) (0)
- Biomaterials as Artificial Niches for Pluripotent Stem Cell Engineering (2014) (0)
- Controllable and robust morphogenesis of functional vascular network assembly within synthetic environments (2011) (0)
- FIBRONECTIN NETWORK INFLUENCES ENDOTHELIAL CELL MIGRATION DURING VASCULAR MORPHOGENESIS IN A BREAST CANCER MODEL (2014) (0)
- Oxygen in cancer and neovascularization (2018) (0)
- Data associated with: Guiding endothelial progenitor cell tube formation using patterned fibronectin surfaces (2019) (0)
- Abstract PR001: Oncogene-induced matrix reorganization controls CD8+ T cell immunity in the UPS microenvironment (2022) (0)
- Editorial overview - Biological engineering: Emerging strategies to understand & engineer the human immune system (2018) (0)
- Engineering the human blood-brain barrier in vitro (2017) (0)
- Skin regeneration with a synthetic biomaterial that replaces the extracellular matrix (2018) (0)
- biocompatible hydrogels based on polysaccharides (2009) (0)
- Modern Mechanobiology (2019) (0)
- Efficient and Scalable Expansion of Human Pluripotent Stem Cells Under Clinically Compliant Settings: A View in 2013 (2013) (0)
- Vascular tissue engineering: biodegradable scaffold platforms to promote angiogenesis (2013) (0)
- Oncogene-induced matrix reorganization controls CD8+ T cell function in the tumor microenvironment (2022) (0)
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