Shazib Pervaiz
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Computer Science
Shazib Pervaiz's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Shazib Pervaiz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. (1998) (621)
- Resveratrol: from grapevines to mammalian biology (2003) (536)
- Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. (2011) (495)
- Annexin 1: the new face of an old molecule (2007) (380)
- Reactive oxygen species and the mitochondrial signaling pathway of cell death. (2005) (366)
- Resveratrol: its biologic targets and functional activity. (2009) (354)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- TNF receptor superfamily‐induced cell death: redox‐dependent execution (2006) (301)
- Cancer stem cell: target for anti‐cancer therapy (2007) (236)
- Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation (2010) (214)
- hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells. (2011) (214)
- Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu (1998) (209)
- Do STAT3 inhibitors have potential in the future for cancer therapy? (2017) (176)
- Oxidative stress regulation of stem and progenitor cells. (2009) (172)
- Superoxide anion: oncogenic reactive oxygen species? (2007) (168)
- The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles. (2009) (153)
- Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis. (1999) (152)
- Redox regulation of p53, redox effectors regulated by p53: a subtle balance. (2012) (149)
- Intracellular Acidification Triggered by Mitochondrial-derived Hydrogen Peroxide Is an Effector Mechanism for Drug-induced Apoptosis in Tumor Cells* (2001) (143)
- Redox regulation of cancer cell migration and invasion. (2013) (141)
- Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies. (2015) (141)
- Caspase‐1 dependent macrophage death induced by Burkholderia pseudomallei (2005) (132)
- Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2 (2011) (131)
- Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells (2007) (130)
- Tumor intracellular redox status and drug resistance--serendipity or a causal relationship? (2004) (128)
- Activation of the RacGTPase inhibits apoptosis in human tumor cells (2001) (125)
- Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2 (2010) (124)
- ART AND SCIENCE OF PHOTODYNAMIC THERAPY (2006) (122)
- Hydrogen Peroxide-Mediated Cytosolic Acidification Is a Signal for Mitochondrial Translocation of Bax during Drug-Induced Apoptosis of Tumor Cells (2004) (121)
- TRAILing death in cancer. (2010) (121)
- Comparison of myoglobin, creatine kinase-MB, and cardiac troponin I for diagnosis of acute myocardial infarction. (1996) (117)
- A permissive apoptotic environment: function of a decrease in intracellular superoxide anion and cytosolic acidification. (2002) (112)
- Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria (2003) (109)
- Apoptosis in the pathophysiology of diabetes mellitus. (2007) (107)
- Intracellular superoxide and hydrogen peroxide concentrations: a critical balance that determines survival or death (2001) (106)
- Mitochondria: Redox Metabolism and Dysfunction (2012) (105)
- Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator. (2014) (100)
- Pro‐oxidant Activity of Low Doses of Resveratrol Inhibits Hydrogen Peroxide—Induced Apoptosis (2003) (94)
- Superoxide anion inhibits drug‐induced tumor cell death (1999) (92)
- Big wheel keeps on turning: apoptosome regulation and its role in chemoresistance (2008) (92)
- Chemotherapeutic potential of the chemopreventive phytoalexin resveratrol. (2004) (91)
- Resveratrol Inhibits Drug-Induced Apoptosis in Human Leukemia Cells by Creating an Intracellular Milieu Nonpermissive for Death Execution (2004) (89)
- LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway. (2005) (86)
- LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. (2009) (86)
- Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2. (2011) (85)
- Resveratrol in cell fate decisions (2007) (83)
- Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt. (2015) (83)
- The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity. (2011) (80)
- Functional proteomics of resveratrol‐induced colon cancer cell apoptosis: Caspase‐6‐mediated cleavage of lamin A is a major signaling loop (2006) (80)
- Apoptosis signaling in cancer stem cells. (2010) (79)
- Reactive oxygen species-mediated regulation of the Na+–H+ exchanger 1 gene expression connects intracellular redox status with cells' sensitivity to death triggers (2006) (75)
- NHE-1: a promising target for novel anti-cancer therapeutics. (2012) (75)
- Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity. (2014) (73)
- Bcl-2 modulates resveratrol-induced ROS production by regulating mitochondrial respiration in tumor cells. (2010) (73)
- Adenine nucleotide translocase family: four isoforms for apoptosis modulation in cancer (2011) (68)
- BCL-2: pro-or anti-oxidant? (2009) (68)
- ROS, autophagy, mitochondria and cancer: Ras, the hidden master? (2013) (67)
- Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases (2013) (67)
- Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer (2011) (65)
- Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance (2018) (64)
- Casein Kinase II: an attractive target for anti-cancer drug design. (2010) (61)
- Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: The roles of caspase-6 and p53 (2008) (60)
- Repression of NHE1 expression by PPARgamma activation is a potential new approach for specific inhibition of the growth of tumor cells in vitro and in vivo. (2009) (59)
- Bcl-2: a prime regulator of mitochondrial redox metabolism in cancer cells. (2011) (59)
- Resveratrol attenuates C5a‐induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities (2009) (58)
- Reactive oxygen‐dependent production of novel photochemotherapeutic agents (2001) (57)
- Noncanonical Cell Fate Regulation by Bcl-2 Proteins. (2020) (56)
- Synergistic anticancer effects achieved by co-delivery of TRAIL and paclitaxel using cationic polymeric micelles. (2011) (55)
- Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model. (2009) (55)
- Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells. (2000) (53)
- Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance. (2005) (52)
- Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase 8-dependent apoptosis in human leukemia and melanoma cells. (1999) (49)
- Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human (2009) (48)
- Hydrogen peroxide-induced apoptosis: oxidative or reductive stress? (2002) (47)
- Resveratrol-from the Bottle to the Bedside? (2001) (45)
- Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma. (2016) (43)
- Comparative analysis of cardiac troponin i and creatine kinase‐MB as markers of acute myocardial infarction (1997) (43)
- A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma (2013) (43)
- LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization (2007) (43)
- Apoptosis and lipoapoptosis in the fission yeast Schizosaccharomyces pombe. (2005) (42)
- Druggability of human disease genes. (2007) (42)
- Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma. (2014) (38)
- The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells. (2010) (38)
- ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells. (2008) (38)
- Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer (2020) (37)
- Synergistic anti-cancer effects via co-delivery of TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) and doxorubicin using micellar nanoparticles. (2011) (36)
- Buried alive: a novel approach to cancer treatment (2004) (35)
- Functional and evolutionary analyses on expressed intronless genes in the mouse genome (2006) (35)
- TUMOR CELL SPECIFIC DARK CYTOTOXICITY OF LIGHT‐EXPOSED MEROCYANINE 540: IMPLICATIONS FOR SYSTEMIC THERAPY WITHOUT LIGHT (1990) (35)
- Assessment of oxidative stress-induced DNA damage by immunoflourescent analysis of 8-oxodG. (2011) (34)
- Elimination of clonogenic tumor cells from HL-60, Daudi, and U-937 cell lines by laser photoradiation therapy: implications for autologous bone marrow purging. (1989) (34)
- Mitochondria-mediated oxidative stress during viral infection. (2022) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Pro-oxidant milieu blunts scissors: insight into tumor progression, drug resistance, and novel druggable targets. (2006) (33)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Correction: Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation (2016) (31)
- Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase. (2010) (31)
- Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide (2015) (31)
- Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS Production. (2016) (29)
- Spontaneous and 5-fluorouracil-induced centrosome amplification lowers the threshold to resveratrol-evoked apoptosis in colon cancer cells. (2010) (29)
- Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression (2019) (28)
- Production of intracellular superoxide mediates dithiothreitol-dependent inhibition of apoptotic cell death. (2005) (28)
- The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88. (2011) (27)
- Targeting Cell Metabolism as Cancer Therapy. (2019) (27)
- Oxidative repression of NHE1 gene expression involves iron-mediated caspase activity (2007) (26)
- MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management (2018) (26)
- Influence of cell culture configuration on the post-cryopreservation viability of primary rat hepatocytes. (2012) (24)
- A High-Content Phenotypic Screen Reveals the Disruptive Potency of Quinacrine and 3′,4′-Dichlorobenzamil on the Digestive Vacuole of Plasmodium falciparum (2013) (24)
- Cross Talk Between Cellular Redox State and the Antiapoptotic Protein Bcl-2. (2018) (24)
- A distinct reactive oxygen species profile confers chemoresistance in glioma-propagating cells and associates with patient survival outcome. (2013) (23)
- Simultaneous analysis of steady‐state intracellular pH and cell morphology by automated laser scanning cytometry (2007) (23)
- Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells (2012) (22)
- Automated laser scanning cytometry: A powerful tool for multi‐parameter analysis of drug‐induced apoptosis (2007) (22)
- The redox-senescence axis and its therapeutic targeting (2021) (21)
- The three Rs along the TRAIL: Resistance, re-sensitization and reactive oxygen species (ROS) (2012) (21)
- Dominant negative Rac1 attenuates paclitaxel‐induced apoptosis in human melanoma cells through upregulation of heat shock protein 27: A functional proteomic analysis (2007) (21)
- Caspase proteases mediate apoptosis induced by anticancer agent preactivated MC540 in human tumor cell lines. (1998) (21)
- Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism (2020) (20)
- Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation? (2013) (20)
- Cleavage of misfolded nuclear receptor corepressor confers resistance to unfolded protein response-induced apoptosis. (2006) (20)
- Protein damage by photoproducts of merocyanine 540. (1992) (19)
- FLIP: a flop for execution signals. (2013) (19)
- Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion (2016) (18)
- A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression. (2019) (18)
- Involvement of Reactive Oxygen Species in Apoptosis Induced by Pharmacological Inhibition of Protein Kinase CK2 (2009) (17)
- Anti-cancer drugs of today and tomorrow: are we close to making the turn from treating to curing cancer? (2002) (17)
- Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison. (2018) (16)
- The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88 (2011) (16)
- Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27 (2013) (16)
- Hippo circuitry and the redox modulation of hippo components in cancer cell fate decisions. (2015) (15)
- Preactivation--a novel antitumour and antiviral approach. (1990) (15)
- Resveratrol regulates the expression of NHE-1 by repressing its promoter activity: critical involvement of intracellular H2O2 and caspases 3 and 6 in the absence of cell death. (2009) (14)
- Preactivated merocyanine 540 inactivates HIV-1 and SIV: potential therapeutic and blood banking applications. (1992) (14)
- Interplay between Mitochondrial Metabolism and Cellular Redox State Dictates Cancer Cell Survival (2021) (14)
- Smac-mediated sensitization of human B-lymphoma cells to staurosporine- and lactacystin-triggered apoptosis is apoptosome-dependent (2007) (13)
- Breast Cancer: A Molecular and Redox Snapshot. (2016) (13)
- Understanding the cancer stem cell phenotype: A step forward in the therapeutic management of cancer. (2019) (13)
- Synergy between preactivated photofrin-II and tamoxifen in killing retrofibroma, pseudomyxoma and breast cancer cells. (1991) (13)
- LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer (2020) (12)
- Mitochondria: The Anti- cancer Target for the Third Millennium (2014) (10)
- Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells (2015) (10)
- Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract (2018) (10)
- Redox signaling in the pathogenesis of human disease and the regulatory role of autophagy. (2020) (10)
- Reactive oxygen species (ROS) and sensitization to TRAIL-induced apoptosis, in Bayesian network modelling of HeLa cell response to LY303511. (2012) (9)
- Developing Physician Leaders for Over 50 years: The Duke Medical Student Research Experience in the US and Singapore (2011) (8)
- Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc (2020) (8)
- Mechanism of apoptosis by resveratrol (2005) (8)
- The anti-oxidant and pro-oxidant dichotomy of Bcl-2 (2016) (8)
- Redox Dichotomy in Cell Fate Decision: Evasive Mechanism or Achilles Heel? (2018) (8)
- Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation (2020) (8)
- Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP (2019) (8)
- Proceedings of the 1st Liaquat University of Medical & Health Sciences (LUMHS) International Medical Research Conference (2017) (7)
- Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP (2012) (7)
- Biphasic activity of CD137 ligand‐stimulated monocytes on T cell apoptosis and proliferation (2011) (7)
- Resveratrol attenuates TLR-4 mediated inflammation and elicits therapeutic potential in models of sepsis (2020) (7)
- ERK 1 / 2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells (6)
- mitoEnergetics and cancer cell fate. (2009) (6)
- Repressing the activity of protein kinase CK2 releases the brakes on mitochondria-mediated apoptosis in cancer cells. (2011) (5)
- Biodistribution and toxicity of photoproducts of merocyanine 540 (2004) (5)
- Reactive Oxygen Species in Cell Fate Decisions (2009) (5)
- Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas (2016) (5)
- KIF1Bβ increases ROS to mediate apoptosis and reinforces its protein expression through O2− in a positive feedback mechanism in neuroblastoma (2017) (5)
- Cell signaling and fate through the redox lens (2019) (4)
- PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production (2022) (4)
- Laser Light Induced Photosensitization Of Lymphomas Cells And Normal Bone Marrow Cells (1988) (4)
- Cellular senescence: Silent operator and therapeutic target in cancer (2021) (4)
- COMPUTATIONAL MODELING OF PATHWAY DYNAMICS FOR DETECTING DRUG EFFECTS : PARADOXICAL EFFECTS OF LY 303511 ON TRAIL-INDUCED APOPTOSIS (2009) (3)
- Correction: Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution. (2015) (3)
- Bcl-2 phosphorylation permits a conducive pro-oxidant milieu for cancer cell survival and progression (2018) (2)
- Akt mediated ROS-dependent selective targeting of mutant KRAS tumors. (2014) (2)
- Crosstalk Between p53 and Mitochondrial Metabolism (2014) (2)
- Redox pioneer: professor Barry Halliwell. (2011) (2)
- Abstract 3080: OPB-51602: a novel STAT3 inhibitor that targets mitochondrial respiratory chain and triggers STAT3 dependent ROS production (2016) (2)
- Abstract P6-18-20: Targeting mitochondrial function for the treatment of triple negative breast cancer: Development of a small molecule inhibitor against mitochondrial STAT3 (2019) (2)
- gRASping the redox lever to modulate cancer cell fate signaling (2018) (2)
- Serine-70 Phosphorylation of Bcl-2 Activates its Redox Rheostat Function to Prevent DNA Damage-induced Execution of Cancer Cells (2017) (1)
- Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53−/− cells to trigger G2/M arrest and senescence (2021) (1)
- Resveratrol The Promise Therein (2004) (1)
- PLK1 inhibition selectively kills ARID1A deficient cells through uncoupling of oxygen consumption from ATP production (2021) (1)
- Abstract 3959: Targeting BCL2 family protein phosphorylation in venetoclax resistant lymphoid malignancies (2022) (1)
- Purification, characterization and preparation immunomatrixes of S‐layer proteins of Thermobifida fusca (2013) (1)
- LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer: Erratum (2021) (1)
- Tumor Pro-oxidant Enviroment Stabilizes Onco-protein c-Myc via Sustained Phosphorylation at Serine 62 that Promotes its Oncogenic Activity (2017) (1)
- Abstract 4884: OXPHOS: A novel target for cancer therapy in oncogene addicted tumor (2018) (0)
- mTORC2 mediated ROS-induced Activation of Akt Selectively Targets Mutant KRAS Addicted Cancers (2022) (0)
- Abstract 5577: STAT3 phosphorylation and Bcl-2 expression as a predictive signature for stratifying clinical lymphomas. (2013) (0)
- Superoxide Promotes Chemoresistance Via the Selective Inhibitory Tyrosine Nitration of Protein Phosphatase 2A-B56δSubunit and the Accumulation of Activated S70-Phosphobcl-2 (2011) (0)
- Role of intracellular ROS in the regulation of tumor cell death by Casein Kinase II (CK2) (2007) (0)
- Abstract 259: Interplay between Bcl-2 and cFLIP in lymphoma disease progression is a function of an altered redox milieu (2019) (0)
- Up-regulation of Death Receptors Mitogen-Activated Protein Kinase Activation and Mediated − Neuroblastoma Cells via Hydrogen Peroxide LY 303511 Enhances TRAIL Sensitivity of SHEP-1 (2009) (0)
- Abstract 3685: Redox regulation of p53 stability is a function of inhibition of PP2A-mediated dephosphorylation at threonine 55 (2016) (0)
- Abstract 4698: Mechanism of glucose deprivation-induced sensitization of tumor cells to receptor-mediated apoptosis: Downregulation of intracellular superoxide anion and cFLIP (2011) (0)
- Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production (2022) (0)
- Redox-dependent targeting of mutant RAS driven cancers (2017) (0)
- Abstract 3097: Structural and biophysical characterization of anti-apoptotic protein Bcl-2 and GTPase Rac1 interaction (2016) (0)
- Abstract 2003: STAT3 is a critical mediator of the pro-survival effect of Bcl-2-Rac1 interaction in human cancer cells (2012) (0)
- Rac1-induced ROS is implicated in the sustained activation of anti-apoptotic protein Bcl-2 in cancer cells (2018) (0)
- Issue Information (2023) (0)
- Neurohormetic Properties of the Phytochemical Resveratrol (2009) (0)
- Abstract 4913: Systematic analysis of LY30-induced sensitization of cancer cells to TRAIL (2011) (0)
- Abstract 363: Intracellular redox milieu regulates Mcl-1 and decreases overall mitochondrial priming in hematopoietic cancers (2022) (0)
- Evaluation of pharmacodynamic (PD) biomarkers in advanced cancer patients treated with oxidative phosphorylation (OXPHOS) inhibitor, OPC-317 (OPC) (2019) (0)
- Redox Rheostat Activity of Serine 70 Phosphorylated Bcl-2 Prevents DNA Damage-Induced Execution of Cancer Cells (2016) (0)
- Abstract LB-139: Laser scanning cytometry for the imaging and quantitation of membrane lipid rafts in cancer cells (2010) (0)
- Synergistic anticancer effects via co-delivery of TNF-related apoptosis-inducing ligand (TRAIL) and doxorubicin using micellar polymer nanoparticles (2012) (0)
- Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD (2023) (0)
- Abstract 5807: MDM2 mitochondrial translocation mediates metabolic reprogramming towards OXPHOS in TKI-resistant oncogene-addicted cancer (2022) (0)
- 3-Kinase-Akt Pathway Production Independent of the Phosphoinositide PeroxideDrug-Induced Apoptosis via Intracellular Hydrogen LY 294002 and LY 303511 Sensitize Tumor Cells (2005) (0)
- Clinical Applications of Photodynamic Therapy: A Review (1990) (0)
- Redox dependent selective targeting of mutant K-Ras expressing cancer cells (2016) (0)
- 230 - Redox Modification of B56 y Sub-Unit of PP2A Promotes Carcinogenesis (2015) (0)
- Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells. (2014) (0)
- 307 - Redox Dependent Synthetic Lethality of a Novel Small Molecule againstMutant KRAS (2014) (0)
- Biological activity of photoproducts of merocyanine 540 generated by laser-light activation (1992) (0)
- Abstract 1945: Modulation of intracellular redox milieu regulates Mcl-1 levels and sensitizes venetoclax resistant cancer cells (2021) (0)
- Bcl-2 phosphorylation at serine-70 protects cancer cells from ROS-induced DNA damage and cell death by engaging the mitochondrial respiratory system (2018) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Combination effects of resveratrol and 5-fluorouracil on human colon cancer cells (2007) (0)
- Abstract 5278: Superoxide mediated selective tyrosine nitration of protein phosphatase 2A-B56δ stabilizes Bcl-2 phosphorylation and its anti-apoptotic activity (2014) (0)
- Abstract C149: STAT3 is a critical mediator of the prosurvival effect of Bcl-2-Rac1 interaction in human cancer cells. (2011) (0)
- Comparison of M yoglobin , Creatine Kinase-MB , and Cardiac Troponin I for Diagnosis of Acute Myocardial Infarction * (2015) (0)
- Editorial [Hot Topic: Cancer Cell Redox Status: Novel Target for Designing Strategies to Overcome Apoptosis Resistance (Executive Editor: S. Pervaiz)] (2006) (0)
- Journal roundup (2008) (0)
- Singlet oxygen-mediated generation of dye-based toxins: Implications for systemic therapy (1990) (0)
- Upregulation of the orphan nuclear receptor NR4A3 in drug-induced apoptosis of tumor cells and its relationship to mitochondrial VDAC1 (2007) (0)
- Targeting of Mutant KRAS Driven Tumors by a Novel Small Molecule is Associated with ROS-Driven Mitophagy and Changes in Mitochondrial Morphology (2016) (0)
- 146 – Superoxide Anion Mediated Post-Translational Regulation of C-Myc Oncoprotein (2015) (0)
- Abstract 4611: Novel lysosomotrophic agent inhibits in vivo tumor formation and triggers calcium-dependent cell death in a variety of human cancer cell lines (2014) (0)
- Conference roundup MAC 2011. (2013) (0)
- 124 - Bcl-2 Phosphorylation Induces Negative Feedback Upon Oxidative Stress by Engaging the Mitochondrial Respiratory System (2015) (0)
- Reactive Oxygen Intermediates Response to Apoptotic Stimuli: Regulate Cellular An Hypothesis (1999) (0)
- Abstract 4076: Redox dependent regulation of cFLIP promoter activity and gene expression by PTEN. (2013) (0)
- Biological Samples Bank and Cancer Research Database: Experience from pilot project at Aga Khan University Hospital, Karachi, Pakistan (2008) (0)
- 1048 POSTER Ligand Activation of PPAR Gamma Enhances Cytotoxicity of Chemotherapeutic Drugs in Breast Cancer Cells: the Mechanism Involving Tumour-specific Suppression of Mitochondrial MnSOD in Vitro and in Vivo (2011) (0)
- Abstract LB-277: A small molecule compound targets mutant Ras driven cancers via changes in mitochondrial morphology and mTOR-dependent execution (2018) (0)
- Correction: Hydrogen Peroxide-Mediated Cytosolic Acidification Is a Signal for Mitochondrial Translocation of Bax during Drug-Induced Apoptosis of Tumor Cells. (2016) (0)
- Cancer25 - Selective Tyrosine Nitration of Protein Phosphatase 2A-B56δ Mediates Superoxide-Induced Bcl-2 Activation (2013) (0)
- Protein Carbonylation in Cancer Cells (2008) (0)
- Abstract 440: The oncogenic activity of a pro-oxidant intracellular milieu is associated with redox dependent activation of NF-kB (2017) (0)
- Corrigendum to “The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells” [Int. J. Biochem. Cell Biol. 42 (2010) 623–629] (2014) (0)
- The tumor environment stabilizes c-Myc oncoprotein through its sustained phosphorylation at serine 62, which promotes its oncogenic activity (2018) (0)
- Abstract 1722: Effectiveness of predictive simulation in identifying potential patient-specific therapeutic targets in multiple myeloma-a pilot study (2015) (0)
- Abstract 1025: Rac1 is a novel binding partner of the anti-apoptotic protein Bcl-2 (2010) (0)
- 470 POSTER Mlecular characterization of cell death signaling by mercaptopyridine oxide and its analogs in human tumor cells-evidence for p53-independent growth arrest (2006) (0)
- Abstract B63: Apaf‐1 mislocalization is a strong indicator of drug resistance in B cell lymphomas (2009) (0)
- Na+/H+ exchanger 1 (NHE-1) redox-regulated gene and intracellular target for the redox control of cell death sensitivity (2011) (0)
- Caspase-6 activation and lamin A cleavage occur in resveratrol-evoked apoptosis of colon cancer cell line (HCT116) cells (2005) (0)
- Editorial: The proceedings of mitochondria apoptosis and cancer (MAC 2021) virtual symposium (2023) (0)
- TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3 (2021) (0)
- Erratum: Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells (Blood. (2000) 95:5 (1773-1780)) (2014) (0)
- Abstract 13: Biophysical evidence for the existence of a functional interaction between the small GTPase Rac-1 and the anti-apoptotic protein Bcl-2 (2015) (0)
- KIF1Bβ increases ROS to mediate apoptosis and reinforces its protein expression through O2− in a positive feedback mechanism in neuroblastoma (2017) (0)
- Abstract 2605: Selective targeting of KRAS mutant cancer cells by a novel small molecule compound (2014) (0)
- Abstract #1466: MAPK-mediated PPAR-\#947; phosphorylation status is a critical determinant in the differential response of neuroblastoma cell lines to PPAR-\#947; ligands (2009) (0)
- Expression of Concern: Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: The roles of caspase-6 and p53 (2020) (0)
- Is Transformed Bone Marrow Cell Line a Substitute for Normal Bone Marrow Cells in Laser Photoradiation Therapy for Bone Marrow Purging (1988) (0)
- Redox Dependent Activation of NF-kB Signaling in Cancer via Superoxide-Induced Phosphorylation of IKK (2017) (0)
- 631 Mislocalization of the apoptosome protein Apaf-1 is a strong marker of drug resistance in B cell lymphomas (2010) (0)
- Apoptosis Gene Information System--AGIS. (2006) (0)
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What Schools Are Affiliated With Shazib Pervaiz?
Shazib Pervaiz is affiliated with the following schools:
