Shekhar C. Mande
#23,521
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Shekhar C. Mande's AcademicInfluence.com Rankings
Shekhar C. Mandebiology Degrees
Biology
#1849
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#2999
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Molecular Biology
#946
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#969
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Shekhar C. Mandephysics Degrees
Physics
#2819
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#4096
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Biophysics
#106
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#114
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Biology Physics
Why Is Shekhar C. Mande Influential?
(Suggest an Edit or Addition)According to Wikipedia, Shekhar C. Mande is Structural and Computational Biologist. He was the Director General of the Council of Scientific and Industrial Research , India, and the Secretary of the Department of Scientific and Industrial Research , Ministry of Science and Technology. Prior to this, he was the Director of National Centre for Cell Science, Pune.
Shekhar C. Mande's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage1 (2009) (185)
- Crystal structure of recombinant human triosephosphate isomerase at 2.8 Å resolution. Triosephosphate isomerase‐related human genetic disorders and comparison with the trypanosomal enzyme (1994) (125)
- Structure of the Heat Shock Protein Chaperonin-10 of Mycobacterium leprae (1996) (124)
- Crystal structure of peanut lectin, a protein with an unusual quaternary structure. (1994) (116)
- The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. (2003) (102)
- Crystal structure of recombinant triosephosphate isomerase from bacillus stearothermophilus. An analysis of potential thermostability factors in six isomerases with known three‐dimensional structures points to the importance of hydrophobic interactions (1995) (91)
- Mycobacterium tuberculosis GroEL homologues unusually exist as lower oligomers and retain the ability to suppress aggregation of substrate proteins. (2004) (88)
- Three hTIM mutants that provide new insights on why TIM is a dimer. (1996) (85)
- Cloning and overexpression of the triosephosphate isomerase genes from psychrophilic and thermophilic bacteria. Structural comparison of the predicted protein sequences. (1993) (80)
- Chimeric Vitreoscilla Hemoglobin (VHb) Carrying a Flavoreductase Domain Relieves Nitrosative Stress in Escherichia coli: New Insight into the Functional Role of VHb (2002) (76)
- The unusual chaperonins of Mycobacterium tuberculosis. (2005) (73)
- The TB structural genomics consortium: providing a structural foundation for drug discovery. (2002) (70)
- Identification of the INO1 gene of Mycobacterium tuberculosis H37Rv reveals a novel class of inositol-1-phosphate synthase enzyme. (1999) (68)
- Multiple Gene Duplication and Rapid Evolution in the groEL Gene: Functional Implications (2006) (67)
- Inferring genome-wide functional linkages in E. coli by combining improved genome context methods: comparison with high-throughput experimental data. (2007) (64)
- Crystal Structure of the 65-Kilodalton Heat Shock Protein, Chaperonin 60.2, of Mycobacterium tuberculosis (2004) (63)
- Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion. (2002) (63)
- Functional Studies of Multiple Thioredoxins from Mycobacterium tuberculosis (2008) (60)
- A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL (2009) (56)
- Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity. (2001) (55)
- Site-directed mutagenesis reveals a novel catalytic mechanism of Mycobacterium tuberculosis alkylhydroperoxidase C. (2002) (54)
- Human recombinant resistin protein displays a tendency to aggregate by forming intermolecular disulfide linkages. (2003) (53)
- Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein. (2008) (52)
- Facilitated Oligomerization of Mycobacterial GroEL: Evidence for Phosphorylation-Mediated Oligomerization (2009) (49)
- Exploiting 3D structural templates for detection of metal‐binding sites in protein structures (2008) (47)
- Multiple chaperonins in bacteria—novel functions and non-canonical behaviors (2015) (46)
- Conserved structural features and sequence patterns in the GroES fold family. (1999) (45)
- Conformational flexibility of Mycobacterium tuberculosis thioredoxin reductase: crystal structure and normal-mode analysis. (2005) (44)
- Protein crystallography and infectious diseases (1994) (43)
- Complex evolution of the inositol-1-phosphate synthase gene among archaea and eubacteria. (2000) (42)
- Function of the central domain of streptokinase in substrate plasminogen docking and processing revealed by site‐directed mutagenesis (1999) (40)
- Dynamic Changes in Protein Functional Linkage Networks Revealed by Integration with Gene Expression Data (2008) (38)
- PAR-3D: a server to predict protein active site residues (2007) (36)
- Stabilization of human triosephosphate isomerase by improvement of the stability of individual alpha-helices in dimeric as well as monomeric forms of the protein. (1996) (36)
- The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions. (2006) (35)
- Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. (2005) (34)
- Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis (2017) (33)
- Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages (2008) (32)
- Involvement of a Nine-residue Loop of Streptokinase in the Generation of Macromolecular Substrate Specificity by the Activator Complex through Interaction with Substrate Kringle Domains* (2002) (32)
- Structural biology of Mycobacterium tuberculosis proteins: the Indian efforts. (2011) (31)
- Understanding Communication Signals during Mycobacterial Latency through Predicted Genome-Wide Protein Interactions and Boolean Modeling (2012) (30)
- Structure of Mycobacterium tuberculosis chaperonin-10 at 3.5 A resolution. (2002) (26)
- Mapping conformational transitions in cyclic AMP receptor protein: crystal structure and normal-mode analysis of Mycobacterium tuberculosis apo-cAMP receptor protein. (2010) (26)
- Rewiring of Metabolic Network in Mycobacterium tuberculosis During Adaptation to Different Stresses (2019) (25)
- Towards understanding the biological function of the unusual chaperonin Cpn60.1 (GroEL1) of Mycobacterium tuberculosis. (2016) (24)
- Prediction of conditional gene essentiality through graph theoretical analysis of genome-wide functional linkages. (2009) (23)
- Identification of an ABC transporter gene that exhibits mRNA level overexpression in fluoroquinolone‐resistant Mycobacterium smegmatis (1998) (22)
- Hemoglobin Biosynthesis in Vitreoscilla stercoraria DW: Cloning, Expression, and Characterization of a New Homolog of a Bacterial Globin Gene (1998) (21)
- Metal ions modulate the plastic nature of Mycobacterium tuberculosis chaperonin-10. (2001) (19)
- Using structural knowledge in the protein data bank to inform the search for potential host-microbe protein interactions in sequence space: application to Mycobacterium tuberculosis (2017) (15)
- Active and prospective latent tuberculosis are associated with different metabolomic profiles: clinical potential for the identification of rapid and non-invasive biomarkers (2020) (14)
- Evolution of Bacterial Chaperonin 60 Paralogues and Moonlighting Activity (2013) (14)
- The mortality due to COVID-19 in different nations is associated with the demographic character of nations and the prevalence of autoimmunity (2020) (13)
- BioSuite: a comprehensive bioinformatics software package (A unique industry-academia collaboration) (2007) (13)
- Three-dimensional Structure of Mycobacterium tuberculosis Chaperonin-10 Reveals a Partially Stable Conformation for its Mobile Loop (2001) (13)
- Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort (2021) (11)
- Protein chaperones and non-protein substrates: on substrate promiscuity of GroEL (2011) (10)
- GroEL2 of Mycobacterium tuberculosis Reveals the Importance of Structural Pliability in Chaperonin Function (2015) (10)
- The crystal structure of Mycobacterium tuberculosis NrdH at 0.87 Å suggests a possible mode of its activity. (2013) (10)
- 16S rDNA based skin microbiome data of healthy individuals and leprosy patients from India (2019) (9)
- A Glimpse Into the Structure and Function of Atypical Type I Chaperonins (2018) (9)
- Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis CRP/FNR family transcription regulator. (2006) (9)
- Differential enrichment of regulatory motifs in the composite network of protein-protein and gene regulatory interactions (2014) (8)
- Mortality Due to COVID-19 in Different Countries is Associated with their Demographic Character and Prevalence of Autoimmunity (2021) (7)
- Metabolomics Studies To Decipher Stress Responses in Mycobacterium smegmatis Point to a Putative Pathway of Methylated Amine Biosynthesis (2019) (7)
- Multiple transcription factors co-regulate the Mycobacterium tuberculosis adaptation response to vitamin C (2019) (6)
- Structural studies on peanut lectin. (1988) (6)
- Spatially conserved motifs in complement control protein domains determine functionality in regulators of complement activation-family proteins (2019) (6)
- Antitrypanosomiasis Drug Development Based on Structures of Glycolytic Enzymes (2018) (5)
- Expression, purification, crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis thioredoxin reductase. (2004) (5)
- A novel function of Mycobacterium tuberculosis chaperonin paralog GroEL1 in copper homeostasis (2020) (4)
- 16S rDNA based skin microbiome data of healthy individuals and leprosy patients from India (2019) (4)
- Genome analysis identifies a spontaneous nonsense mutation in ppsD leading to attenuation of virulence in laboratory-manipulated Mycobacterium tuberculosis (2019) (4)
- Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis (2019) (4)
- Homology Model of a Novel Xylanase: Molecular Basis for High-Thermostability and Alkaline Stability (2000) (4)
- Structural aspects of lesional and non-lesional skin microbiota reveal key community changes in leprosy patients from India (2021) (4)
- A fast algorithm for macromolecular packing calculation (1989) (3)
- Effect of alcohols on protein hydration (2005) (3)
- Crystal Structure of M. tuberculosis Thioredoxin reductase (2005) (3)
- CoRNeA: A Pipeline to Decrypt the Inter-Protein Interfaces from Amino Acid Sequence Information (2020) (3)
- From System-Wide Differential Gene Expression to Perturbed Regulatory Factors: A Combinatorial Approach (2015) (3)
- Paradoxical Case Fatality Rate dichotomy of Covid-19 among rich and poor nations points to the hygiene hypothesis. (2020) (3)
- Mycobacterium tuberculosis Chaperonin60.2 (2004) (3)
- Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network. (2011) (3)
- The Most Wanted Man in China:My Journey from Scientist to Enemy of the State (2016) (3)
- Chaperonin Abundance Boosts Bacterial Fitness (2020) (3)
- Spatially conserved motifs in complement control protein domains determine functionality in regulators of complement activation-family proteins (2019) (3)
- Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis (2018) (2)
- Cation-Mediated Interplay of Loops in Chaperonin-10 (2006) (2)
- Structure–sequence features based prediction of phosphosites of serine/threonine protein kinases of Mycobacterium tuberculosis (2021) (2)
- Multiple transcription factors co-regulate the Mycobacterium tuberculosis adaptation response to vitamin C (2019) (2)
- Identification of conserved residue patterns in small beta-barrel proteins. (2002) (2)
- Chapter 3- Probing Gene Regulatory Networksto Decipher Host–Pathogen Interactions (2013) (2)
- Role of S&T organisations in mitigation of Covid-19: CSIR as a case study (2020) (1)
- Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis chorismate mutase. (2005) (1)
- Analysis of Dihedral Angle Variability in Related Protein Structures (2013) (1)
- Early developments in crystallography (2014) (1)
- CoRNeA: A pipeline to decrypt the inter protein interfaces from amino acid sequence information (2019) (1)
- Chaperonin Abundance Enhances Bacterial Fitness (2021) (1)
- A novel function of M. tuberculosis chaperonin paralog GroEL1 in copper homeostasis (2019) (1)
- Identification of conserved residue patterns in small β-barrel proteins (2002) (1)
- Redox Proteins of Mycobacterium tuberculosis (2014) (1)
- Probing Gene Regulatory Networks to Decipher Host–Pathogen Interactions (2013) (1)
- Identification of self-consistent modulons from bacterial microarray expression data with the help of structured regulon gene sets (2013) (1)
- Staufen‐2 functions as a cofactor for enhanced Rev‐mediated nucleocytoplasmic trafficking of HIV‐1 genomic RNA via the CRM1 pathway (2022) (1)
- Using operonic gene pairs to set the threshold correlation coefficient for differently expressed genes (2011) (1)
- Nobel Prize in Physiology or Medicine 2016 (2016) (0)
- Characterization of a New Homolog of a DW: Cloning, Expression, and stercoraria Vitreoscilla Hemoglobin Biosynthesis in (2013) (0)
- Indian Human Microbiome Initiative:Indian-Ness through the Magnifying Glass (2017) (0)
- high-throughput experimental data improved genome context methods: Comparison with by combining E. coli Inferring genome-wide functional linkages in (2007) (0)
- Improved modulon identification from bacterial gene expression array data using operon-based correlation reference set (2010) (0)
- Obituary: My Fond Remembrances of Dr M.K. Bhan (2020) (0)
- Multiple chaperonins in bacteria—novel functions and non-canonical behaviors (2015) (0)
- The role of thioredoxin proteins in Mycobacterium tuberculosis probed by proteome-wide target profiling (2022) (0)
- Structural and functional studies on Mycobacterium tuberculosis ribonucleotide reductase (2017) (0)
- High-resolution crystal structure of Glutaredoxin like protein NrdH from Mycobacterium tuberculosis. (2013) (0)
- Crystal structure of peanut lectin, a protein with an open quaternary arrangement (1993) (0)
- Crystal structure of CRP (cAMP receptor Protein) from Mycobacterium tuberculosis (2010) (0)
- Crystal structure of the immunodominant chaperonin-10 of Mycobacterium leprae (1996) (0)
- Streptokinase: Direct evidence for β-domain's role in substrate PG interaction (2000) (0)
- Early developments in crystallography (2014) (0)
- THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE (1997) (0)
- Crystal Structure of M. tuberculosis YefM antitoxin (2008) (0)
- TRIOSEPHOSPHATE ISOMERASE (TIM) COMPLEXED WITH 2-PHOSPHOGLYCOLIC ACID (1996) (0)
- Harnessing Science, Technology & Innovation : Making India a Global Player (2020) (0)
- In silico identification of CCP sequence motifs allow identification of novel complement regulators. (2016) (0)
- Purification and preliminary crystallization experiments on DNA-binding proteins human topoisomerase 1 and HIV-2 integrase (1993) (0)
- Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillus anthracis (2017) (0)
- Structural similarity between peanut lectin and concanavalin A (1987) (0)
- Nobel Prize in Physiology or Medicine 2016 (2017) (0)
- Genome analysis identifies a spontaneous nonsense mutation in ppsD leading to attenuation of virulence in laboratory-manipulated Mycobacterium tuberculosis (2019) (0)
- Biology across Scales:Historical Perspective on Some Indian Contributions (2016) (0)
- [Using the operonic gene pairs for establishing the treshold for correlation coefficient of differently expressed genes]. (2011) (0)
- High resolution structure of M.tb NRDH (2014) (0)
- Correction for Kumar et al., “Facilitated Oligomerization of Mycobacterial GroEL: Evidence for Phosphorylation-Mediated Oligomerization” (2020) (0)
- The PPE Protein Rv1196 of Mycobacterium tuberculosis Exploits the TLR2 Signaling in Macrophages Eliciting an Anti-Inflammatory Response by Producing IL-10 (2008) (0)
- Functional Diversity in Mycobacterial Chaperonins: The Generalists and the Specialists (2017) (0)
- Mycobacterium tuberculosis heat shock protein-60 inhibits IL-12 through nitric oxide dependent regulation of p38 MAP kinase and c-rel signalling (2004) (0)
- Crystal structure of glutaredoxin-like NrdH from Mycobacterium tuberculosis (2013) (0)
- Using structural knowledge in the protein data bank to inform the search for potential host-microbe protein interactions in sequence space: application to Mycobacterium tuberculosis (2017) (0)
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