Shelley Berger
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American geneticist
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Shelley Bergerbiology Degrees
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Biology
Shelley Berger's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Shelley Berger Influential?
(Suggest an Edit or Addition)According to Wikipedia, Shelley L. Berger is the Daniel S. Och Professor of cell and developmental biology at the University of Pennsylvania School of Medicine. Her research focuses on epigenetics. Education and career Berger graduated from the University of Michigan Ann Arbor with a BS in biology in 1982 and a PhD in cell and molecular biology in 1987. She did a postdoctoral fellowship at MIT. Prior to joining the University of Pennsylvania faculty, she was the Hilary Koprowski Professor at the Wistar Institute in Philadelphia.
Shelley Berger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The complex language of chromatin regulation during transcription (2007) (2727)
- Acetylation of Histones and Transcription-Related Factors (2000) (1784)
- IDH mutation impairs histone demethylation and results in a block to cell differentiation (2012) (1673)
- An operational definition of epigenetics. (2009) (1627)
- Geroscience: Linking Aging to Chronic Disease (2014) (1391)
- Histone modifications in transcriptional regulation. (2002) (1245)
- Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. (1997) (1100)
- Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map (2007) (908)
- New Nomenclature for Chromatin-Modifying Enzymes (2007) (904)
- p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage (1999) (816)
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade (2016) (801)
- The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity (1996) (760)
- Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. (2001) (730)
- Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. (2003) (727)
- p53 is regulated by the lysine demethylase LSD1 (2007) (716)
- Cytoplasmic chromatin triggers inflammation in senescence and cancer (2017) (681)
- BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression (1998) (678)
- TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion (2019) (677)
- Histone H4 lysine-16 acetylation regulates cellular lifespan (2009) (589)
- Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. (2000) (587)
- Repression of p53 activity by Smyd2-mediated methylation (2006) (566)
- Epigenetic Mechanisms of Longevity and Aging (2016) (551)
- Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells (2018) (466)
- Autophagy mediates degradation of nuclear lamina (2015) (450)
- Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains (1992) (436)
- Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator (2010) (432)
- Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape (2013) (430)
- Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. (2011) (421)
- The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. (2008) (396)
- Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription (2001) (390)
- Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. (2006) (376)
- Lysosome-mediated processing of chromatin in senescence (2013) (367)
- Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction (1999) (354)
- Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation (2010) (351)
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53* (2010) (341)
- Genome-wide and Caste-Specific DNA Methylomes of the Ants Camponotus floridanus and Harpegnathos saltator (2012) (333)
- Crosstalk between CARM1 Methylation and CBP Acetylation on Histone H3 (2002) (309)
- Protein Acetylation Microarray Reveals that NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis (2009) (306)
- TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. (2019) (290)
- The emerging field of dynamic lysine methylation of non-histone proteins. (2008) (288)
- Prevalent p53 mutants co-opt chromatin pathways to drive cancer growth (2015) (282)
- Senescent cells harbour features of the cancer epigenome (2013) (270)
- ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY (2017) (270)
- Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors (1990) (269)
- The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. (2008) (263)
- Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide (1999) (252)
- RNA Binding to CBP Stimulates Histone Acetylation and Transcription (2017) (252)
- Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. (1998) (242)
- Activating Signal Cointegrator 2 Belongs to a Novel Steady-State Complex That Contains a Subset of Trithorax Group Proteins (2003) (236)
- H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. (2007) (234)
- Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. (2004) (233)
- Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality (2013) (224)
- Regulation of chromatin and gene expression by metabolic enzymes and metabolites (2018) (223)
- Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo (1997) (223)
- Catalytic Mechanism and Function of Invariant Glutamic Acid 173 from the Histone Acetyltransferase GCN5 Transcriptional Coactivator* (1999) (217)
- Epigenetics of aging and aging-related disease. (2014) (206)
- Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5 (1996) (199)
- Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. (2005) (198)
- CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein. (1997) (196)
- Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding Protein (*) (1995) (196)
- The ADA Complex Is a Distinct Histone Acetyltransferase Complex in Saccharomyces cerevisiae (1999) (191)
- Epigenetic Regulation in Neurodegenerative Diseases (2018) (188)
- The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. (1998) (185)
- Phylogenetic and Transcriptomic Analysis of Chemosensory Receptors in a Pair of Divergent Ant Species Reveals Sex-Specific Signatures of Odor Coding (2012) (181)
- In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. (2006) (181)
- Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus (2016) (177)
- Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. (1999) (174)
- Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease (2018) (171)
- Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation (1997) (167)
- H3K36 methylation promotes longevity by enhancing transcriptional fidelity (2015) (167)
- Phosphorylation of Histone H4 Serine 1 during DNA Damage Requires Casein Kinase II in S. cerevisiae (2005) (165)
- Eusocial insects as emerging models for behavioural epigenetics (2014) (164)
- An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants (2017) (164)
- Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. (2000) (161)
- During Lytic Infection Herpes Simplex Virus Type 1 Is Associated with Histones Bearing Modifications That Correlate with Active Transcription (2004) (160)
- Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity (1997) (158)
- A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. (1999) (158)
- Histone acetyltransferase complexes. (1999) (157)
- Gene activation by histone and factor acetyltransferases. (1999) (157)
- DNA methylation in social insects: how epigenetics can control behavior and longevity. (2015) (153)
- Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. (2003) (153)
- Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A (1999) (150)
- Acetylation of Yeast AMPK Controls Intrinsic Aging Independently of Caloric Restriction (2011) (147)
- H2B Ubiquitin Protease Ubp8 and Sgf11 Constitute a Discrete Functional Module within the Saccharomyces cerevisiae SAGA Complex (2005) (145)
- Inhibition of TATA-Binding Protein Function by SAGA Subunits Spt3 and Spt8 at Gcn4-Activated Promoters (2000) (141)
- SIRT1 is downregulated by autophagy in senescence and aging (2020) (140)
- Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence (2020) (133)
- Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures (1997) (132)
- The SANT Domain of Ada2 Is Required for Normal Acetylation of Histones by the Yeast SAGA Complex* (2002) (132)
- An embarrassment of niches: the many covalent modifications of histones in transcriptional regulation (2001) (131)
- The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants (2017) (130)
- Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T cell dysfunction. (2020) (130)
- Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast. (1998) (128)
- SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription (2002) (127)
- A chromatin link to caste identity in the carpenter ant Camponotus floridanus (2013) (125)
- Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. (2006) (119)
- Repression of GCN5 Histone Acetyltransferase Activity via Bromodomain-Mediated Binding and Phosphorylation by the Ku–DNA-Dependent Protein Kinase Complex (1998) (119)
- MYST protein acetyltransferase activity requires active site lysine autoacetylation (2012) (118)
- An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease (2020) (115)
- Histone modifications: Now summoning sumoylation (2003) (115)
- MLL1 is essential for the senescence-associated secretory phenotype (2016) (115)
- Chemoreceptor Evolution in Hymenoptera and Its Implications for the Evolution of Eusociality (2015) (114)
- Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members. (1998) (114)
- LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation. (2006) (111)
- Trimethylation of Histone H3 Lysine 4 by Set1 in the Lytic Infection of Human Herpes Simplex Virus 1 (2006) (109)
- The Histone Variant H3.3 Regulates Gene Expression during Lytic Infection with Herpes Simplex Virus Type 1 (2008) (108)
- Cuticular Hydrocarbon Pheromones for Social Behavior and Their Coding in the Ant Antenna. (2015) (108)
- Histone H3 phosphorylation can promote TBP recruitment through distinct promoter‐specific mechanisms (2005) (107)
- Metabolic Signaling to Chromatin. (2016) (105)
- Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription. (2004) (103)
- TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity (2015) (99)
- 14-3-3 Interaction with Histone H3 Involves a Dual Modification Pattern of Phosphoacetylation (2008) (99)
- Structure and function of bromodomains in chromatin-regulating complexes. (2001) (96)
- Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. (2010) (96)
- Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells (2016) (89)
- Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones (2017) (85)
- Structural and Functional Analysis of Yeast Putative Adaptors (1996) (84)
- CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma. (2015) (78)
- Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. (2019) (76)
- Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling (2018) (75)
- Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model (2013) (75)
- An NK-like CAR T cell transition in CAR T cell dysfunction (2021) (73)
- Separation of spermatogenic cell types using STA-PUT velocity sedimentation. (2013) (73)
- Cutting Edge: Persistently Open Chromatin at Effector Gene Loci in Resting Memory CD8+ T Cells Independent of Transcriptional Status (2011) (70)
- Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. (2014) (70)
- KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis (2018) (69)
- Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. (2006) (69)
- A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription (2003) (67)
- Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. (2008) (66)
- Functional characterization of odorant receptors in the ponerine ant, Harpegnathos saltator (2017) (65)
- Trimethylation of Histone H 3 Lysine 4 by Set 1 in the Lytic Infection of Human Herpes Simplex Virus 1 (2006) (64)
- Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products. (1985) (63)
- Trans-tail histone modifications: wedge or bridge? (2002) (62)
- Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence (2016) (61)
- The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. (2014) (61)
- Activation of Chromosomal DNA Replication inSaccharomyces cerevisiae by Acidic Transcriptional Activation Domains (1998) (60)
- In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer (2021) (58)
- Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability (2016) (57)
- TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling (2017) (56)
- Stable-isotope-labeled Histone Peptide Library for Histone Post-translational Modification and Variant Quantification by Mass Spectrometry * (2014) (56)
- CTCF-Dependent Chromatin Boundary Element between the Latency-Associated Transcript and ICP0 Promoters in the Herpes Simplex Virus Type 1 Genome (2007) (56)
- Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform (2018) (55)
- Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest (2015) (55)
- Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction (2010) (51)
- Histone H3 K4 Demethylation during Activation and Attenuation of GAL1 Transcription in Saccharomyces cerevisiae (2007) (50)
- GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor. (2000) (50)
- Structural and Functional Analysis of Yeast Putative Adaptors EVIDENCE FOR AN ADAPTOR COMPLEX IN VIVO * (1996) (49)
- Epigenetic Drugs Can Stimulate Metastasis through Enhanced Expression of the Pro-Metastatic Ezrin Gene (2010) (49)
- Chromatin goes global. (2001) (48)
- Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication (1987) (46)
- The Histone Modification Circus (2001) (46)
- Histone Methylation Has Dynamics Distinct from Those of Histone Acetylation in Cell Cycle Reentry from Quiescence (2014) (41)
- β-Hydroxybutyrate suppresses colorectal cancer (2022) (41)
- The contribution of epigenetic memory to immunologic memory. (2011) (41)
- Characterization of BRD4 during Mammalian Postmeiotic Sperm Development (2015) (37)
- The interplay between epigenetic changes and the p53 protein in stem cells (2017) (36)
- Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis. (2019) (35)
- Genome reprogramming during sporulation. (2009) (35)
- Loss of epigenetic information as a cause of mammalian aging (2023) (34)
- Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress (2016) (33)
- SIRT1 – a new mammalian substrate of nuclear autophagy (2020) (33)
- A Feed-Forward Repression Mechanism Anchors the Sin3/Histone Deacetylase and N-CoR/SMRT Corepressors on Chromatin (2006) (33)
- Use of Differential Display Reverse Transcription-PCR To Reveal Cellular Changes during Stimuli That Result in Herpes Simplex Virus Type 1 Reactivation from Latency: Upregulation of Immediate-Early Cellular Response Genes TIS7, Interferon, and Interferon Regulatory Factor-1 (1998) (32)
- Histone modification signatures in human sperm distinguish clinical abnormalities (2019) (32)
- Chemosensory sensitivity reflects reproductive status in the ant Harpegnathos saltator (2017) (32)
- Keeping p53 in Check: A High-Stakes Balancing Act (2010) (31)
- Lysine methylation represses p53 activity in teratocarcinoma cancer cells (2016) (31)
- Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals (2019) (31)
- Interplay between chromatin modifying and remodeling complexes in transcriptional regulation. (1999) (30)
- H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast (2011) (30)
- The Linker Histone Plays a Dual Role during Gametogenesis in Saccharomyces cerevisiae (2012) (30)
- Chromatin dynamics during herpes simplex virus-1 lytic infection. (2010) (30)
- Identification and characterization of novel sirtuin inhibitor scaffolds. (2009) (30)
- Sumoylation of the yeast Gcn5 protein. (2006) (29)
- Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. (2011) (27)
- Humanized H19/Igf2 locus reveals diverged imprinting mechanism between mouse and human and reflects Silver–Russell syndrome phenotypes (2016) (26)
- p63 establishes epithelial enhancers at critical craniofacial development genes (2019) (26)
- H2B ubiquitylation and de-ubiquitylation in gene activation. (2004) (25)
- eRNA binding produces tailored CBP activity profiles to regulate gene expression (2017) (24)
- A rare DNA contact mutation in cancer confers p53 gain‐of‐function and tumor cell survival via TNFAIP8 induction (2016) (24)
- Gene regulation: Local or global? (2000) (24)
- SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry (2022) (24)
- TEX15 associates with MILI and silences transposable elements in male germ cells (2020) (24)
- Epigenetic Regulator CoREST Controls Social Behavior in Ants. (2019) (22)
- The histone H 2 B-specific ubiquitin ligase RNF 20 / hBRE 1 acts as a putative tumor suppressor through selective regulation of gene expression (2008) (22)
- Genome-wide epigenetics. (2013) (22)
- Senescence Elicits Stemness: A Surprising Mechanism for Cancer Relapse. (2018) (21)
- H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis. (2015) (21)
- Social reprogramming in ants induces longevity-associated glia remodeling (2020) (21)
- Histone H2B ubiquitylation and deubiquitylation in genomic regulation. (2004) (21)
- Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p (2012) (21)
- Gene Array Analysis Reveals Changes in Peripheral Nervous System Gene Expression following Stimuli That Result in Reactivation of Latent Herpes Simplex Virus Type 1: Induction of Transcription Factor Bcl-3 (2001) (20)
- p53 mediates target gene association with nuclear speckles for amplified RNA expression. (2021) (20)
- Identification and analysis of native nucleosomal histone acetyltransferase complexes. (1999) (20)
- Histone modification patterns during gene activation. (2004) (20)
- Molecular biology. The histone modification circus. (2001) (19)
- Histone post-translational modifications regulate transcription and silent chromatin in Saccharomyces cerevisiae. (2006) (18)
- Cell signaling and transcriptional regulation via histone phosphorylation. (2010) (18)
- Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae (2010) (18)
- Good fences make good neighbors: barrier elements and genomic regulation. (2004) (17)
- ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency. (2021) (17)
- Out of the jaws of death: PRMT5 steers p53 (2008) (16)
- Development of Organometallic S6K1 Inhibitors (2014) (15)
- The biochemical and genetic discovery of the SAGA complex. (2020) (14)
- The Sustained Impact of Model Organisms—in Genetics and Epigenetics (2016) (13)
- Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease (2018) (13)
- Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones (2021) (13)
- Crystal structure and mechanism of histone acetylation of the yeast GCN 5 transcriptional coactivator (1999) (13)
- Low‐hanging fruit: targeting Brdt in the testes (2012) (13)
- A genetic and molecular toolbox for analyzing histone ubiquitylation and sumoylation in yeast. (2011) (13)
- Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites (2022) (12)
- The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern. (1997) (12)
- Antennal Olfactory Physiology and Behavior of Males of the Ponerine Ant Harpegnathos saltator (2018) (11)
- The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements. (1995) (11)
- Transgenerational inheritance of longevity: epigenetic mysteries abound. (2012) (10)
- Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks (2019) (10)
- Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex. (2008) (10)
- Food for thought (2020) (8)
- Production and cleavage of Drosophila hsp70 transcripts extending beyond the polyadenylation site. (1994) (8)
- Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer. (2022) (8)
- A Novel Human Ada 2 Homologue Functions with Gcn 5 or Brg 1 To Coactivate Transcription (2003) (7)
- pre-mRNA spatial distributions suggest that splicing can occur post-transcriptionally (2020) (6)
- The histone code and beyond : new approaches to cancer therapy (2006) (6)
- A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription (2016) (5)
- BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion (2022) (5)
- EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells. (2022) (5)
- The Histone Code and Beyond (2006) (4)
- Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark (2020) (4)
- ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels (2022) (4)
- The spatial distributions of pre-mRNAs suggest post-transcriptional splicing of specific introns within endogenous genes (2020) (4)
- Characterization of BRD 4 during mammalian post-meiotic sperm development (2017) (3)
- Exploring the Dynamic Relationship Between Cellular Metabolism and Chromatin Structure Using SILAC-Mass Spec and ChIP-Sequencing. (2016) (3)
- CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE (1999) (3)
- In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer (2020) (3)
- Tramtrack acts during late pupal development to direct ant caste identity (2021) (3)
- G9a and Glp methylate lysine 373 in the tumor suppressor p53. (2010) (3)
- SARS-CoV-2 ORF8 encoded protein contains a histone mimic, disrupts chromatin regulation, and enhances replication (2021) (3)
- Genetics Meets Epigenetics in Treg Cells and Autoimmunity. (2020) (3)
- Comparison of genotoxic vs. non-genotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks (2018) (2)
- Leading Edge Commentary Geroscience : Linking Aging to Chronic Disease (2014) (2)
- Abstract 60: Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment (2021) (2)
- Impaired tumor death receptor signaling drives resistance to CAR T cell therapy (2019) (2)
- Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state (2022) (2)
- Long lifespan is maintained by a unique Heat Shock Factor in reproductive ants (2022) (1)
- Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation (2022) (1)
- Spurious intragenic transcription is a hallmark of mammalian cellular senescence and tissue aging (2022) (1)
- Analysis of activity and regulation of hGcn5, a human histone acetyltransferase. (1999) (1)
- Efficient engineering of human and mouse primary cells using peptide-assisted genome editing. (2023) (1)
- Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging (2023) (1)
- A comprehensive assessment of histone modifications in human sperm (2015) (1)
- Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease (2020) (1)
- Polyomavirus Sequences Affecting the Initiation of Transcription and DNA Replication (1987) (1)
- , expression putative tumor suppressor through selective regulation of gene The histone H 2 B-specific ubiquitin ligase RNF 20 / hBRE 1 acts as a data (2008) (1)
- Olfactory receptors are required for social behavior and neural plasticity in ants, as evidenced by CRISPR-mediated gene knockout (2017) (1)
- Hormonal gatekeeping via the blood brain barrier governs behavior (2022) (1)
- A Coalescence of Scientific Cultures (2003) (1)
- Abstract 1239: CDKN2B loss promotes progression from benign melanocytic nevus to melanoma (2015) (1)
- SARS-CoV-2 protein encoded by ORF8 contains a histone mimic that disrupts chromatin regulation (2021) (1)
- Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer (2022) (1)
- Cycle Reentry from Quiescence from Those of Histone Acetylation in Cell Histone Methylation Has Dynamics Distinct (2014) (0)
- A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion (2021) (0)
- Abstract 3602: Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype (2022) (0)
- Ensheathing glia promote increased lifespan and healthy brain aging. (2023) (0)
- Epigenetics: The Many Faces of Epigenetics in Aging (2020) (0)
- Abstract PR011: TXNRD1 drives innate immune response in senescent cells to promote tumor immune surveillance and age-associated inflammation (2023) (0)
- C. David Allis (1951–2023) (2023) (0)
- Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease (2018) (0)
- 102 Epigenetic enhancer disruption as a driver of squamous carcinogenesis (2017) (0)
- Regulation Of Transcription By The Polyomavirus Enhancer And The Adenovirus E1a Gene Products. (1987) (0)
- HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE (1999) (0)
- ACSS2 and the metabolic‐epigenetic axis in Alzheimer’s disease (2020) (0)
- 362 Epigenetic regulation of DNA damage-induced inflammation (2016) (0)
- CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX (1999) (0)
- Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability (2016) (0)
- Globalunfoldingofasubstrateprotein by the Hsp 100 chaperone (1999) (0)
- RNA modification to the rescue! (2021) (0)
- Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T cell-intrinsic Dysfunction. (2023) (0)
- Abstract B104: Impact of PD-1 blockade on epigenetic and transcriptional reprogramming of exhausted T cells (2016) (0)
- Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark (2020) (0)
- and Digestive and Kidney Diseases National Institutes of Health The Structure of Chromatin (2001) (0)
- CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A (1999) (0)
- Structure of the Histone Acetyltransferase Domains of the GCN5, P/CAF and ESA1 Transcriptional Coactivators (2000) (0)
- 624 KMT2D epigenetically regulates p63 target enhancers to coordinate epithelial homeostasis (2018) (0)
- linked to sociality composition and regulation while preserving regulatory features Social insect genomes exhibit dramatic evolution in gene Material Supplemental (2013) (0)
- 14-3-3 Interaction with Histone H3 Involves a Dual Modification Pattern of Phosphoacetylation (cid:1) (2008) (0)
- Author Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry (2023) (0)
- Status T Cells Independent of Transcriptional + CD8at Effector Gene Loci in Resting Memory Cutting Edge: Persistently Open Chromatin (2011) (0)
- Chemosensory sensitivity reflects reproductive status in the ant Harpegnathos saltator (2017) (0)
- Abstract LB205: The IRF8-MEF2D transcription factor circuit regulated by a druggable multiple post-translational modification (PTM) reader ZMYND8 in acute myeloid leukemia (2021) (0)
- β-Hydroxybutyrate suppresses colorectal cancer (2022) (0)
- Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells (2016) (0)
- Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones (2017) (0)
- CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 (1999) (0)
- Epigenetics of Human Neurodegeneration (2020) (0)
- Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells (2018) (0)
- Publisher Correction: SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry (2023) (0)
- In vivo CRISPR Screening Identifies Fli1 as a Transcriptional Safeguard that Restrains Effector CD8 T Cell Differentiation During Infection and Cancer (2020) (0)
- Crystal Structure of Tetrahymena GCN5 with Bound Coenzyme A and a 19-residue Histone H3 Peptide (2003) (0)
- Regulation of chromatin and gene expression by metabolic enzymes and metabolites (2018) (0)
- Terri Grodzicker: advocate and influencer of impactful science (2023) (0)
- Yeast Aging Proteome Unveiled a Novel Aging Regulation Pathway Mediated by the Chromatin Remodeling Complex ISW2 (2012) (0)
- Crystal Structure of Tetrahymena GCN5 with Bound Coenzyme A and a Phosphorylated, 19-residue Histone H3 peptide (2003) (0)
- Proteinsa Subset of Trithorax Group a Novel Steady-State Complex That Activating Signal Cointegrator 2 Belongs to (2014) (0)
- Cuticular Hydrocarbon Ph eromones for Social Behavior and Their Coding in the Ant Antenna Graphical (2015) (0)
- 87: Mutant p53 Can Drive Cancer Initiation and Progression Through Gain-of-Function Properties (2015) (0)
- Antennal Olfactory Physiology and Behavior of Males of the Ponerine Ant Harpegnathos saltator (2018) (0)
- Histone and factor covalent modifications in genome regulation (2009) (0)
- Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia (2022) (0)
- The homeodomain protein Six1 regulates Ezrin gene transcription through recruitment of the CREB-binding protein. (2006) (0)
- Connections between cell senescence, chromatin, and neurodegeneration (2015) (0)
- CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A (2000) (0)
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