Sherif El-Khamisy
#183,254
Most Influential Person Now
Egyptian Professor of Biochemistry and Molecular Genetics
Sherif El-Khamisy's AcademicInfluence.com Rankings
Sherif El-Khamisybiology Degrees
Biology
#15537
World Rank
#19541
Historical Rank
Molecular Biology
#2732
World Rank
#2774
Historical Rank
Biochemistry
#2749
World Rank
#2937
Historical Rank
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Biology
Sherif El-Khamisy's Degrees
- PhD Biochemistry Cairo University
- Masters Biochemistry Cairo University
- Bachelors Biochemistry Cairo University
Why Is Sherif El-Khamisy Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sherif El- Khamisy is an Egyptian Professor of Biochemistry and Molecular Genetics. He is the Director of Research and Innovation and co-founder of the Healthy Life Span Institute, University of Sheffield, United Kingdom. He is also one of the 2022 winners of Obada Prize
Sherif El-Khamisy's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. (2003) (664)
- Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1 (2005) (408)
- The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates (2006) (365)
- A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage (2009) (361)
- The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks (2004) (347)
- TDP1 facilitates chromosomal single‐strand break repair in neurons and is neuroprotective in vivo (2007) (181)
- APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks (2007) (160)
- Topoisomerase-mediated chromosomal break repair: an emerging player in many games (2015) (133)
- TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function (2014) (125)
- C9orf72 Expansion Disrupts ATM-mediated Chromosomal Break Repair (2017) (115)
- Genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 (2009) (102)
- SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits (2017) (99)
- TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 (2012) (84)
- TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks. (2007) (82)
- Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin (2009) (82)
- SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair (2012) (80)
- Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks. (2010) (70)
- ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells (2013) (67)
- Gold aggregating gold: A novel nanoparticle biosensor approach for the direct quantification of hepatitis C virus RNA in clinical samples (2017) (66)
- TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy (2013) (65)
- Nucleic acids biosensors based on metal-organic framework (MOF): Paving the way to clinical laboratory diagnosis. (2019) (65)
- TDP1 serine 81 promotes interaction with DNA ligase IIIα and facilitates cell survival following DNA damage (2010) (63)
- Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan (2014) (61)
- TDP1-dependent DNA single-strand break repair and neurodegeneration. (2006) (59)
- Defective DNA Ligation during Short-Patch Single-Strand Break Repair in Ataxia Oculomotor Apraxia 1 (2008) (58)
- DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1 (2007) (52)
- TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts (2020) (50)
- A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3 (2018) (50)
- Measurement of chromosomal DNA single-strand breaks and replication fork progression rates. (2006) (49)
- To live or to die: a matter of processing damaged DNA termini in neurons (2011) (44)
- Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites (2012) (41)
- Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan (2016) (40)
- Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage (2017) (39)
- UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis (2018) (35)
- P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane (2015) (28)
- Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia (2018) (27)
- A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. (2016) (26)
- TDP1/TOP1 Ratio as a Promising Indicator for the Response of Small Cell Lung Cancer to Topotecan (2014) (25)
- Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits (2017) (23)
- DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity (2021) (23)
- DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms. (2019) (23)
- miR-363 confers taxane resistance in ovarian cancer by targeting the Hippo pathway member, LATS2 (2018) (23)
- Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin (2017) (19)
- Efficient Loading and Encapsulation of Anti-Tuberculosis Drugs using Multifunctional Mesoporous Silicate Nanoparticles (2016) (19)
- Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1 (2016) (18)
- Recent advances in stem cells therapy: A focus on cancer, Parkinson’s and Alzheimer’s (2018) (17)
- Rad5, HLTF, and SHPRH: A Fresh View of an Old Story (2018) (17)
- Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors (2014) (16)
- Short-patch single-strand break repair in ataxia oculomotor apraxia-1. (2009) (16)
- Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing (2014) (15)
- Nucleosides Rescue Replication-Mediated Genome Instability of Human Pluripotent Stem Cells (2019) (15)
- Gold nanoparticles – an optical biosensor for RNA quantification for cancer and neurologic disorders diagnosis (2018) (13)
- Hypoxia-induced SETX links replication stress with the unfolded protein response (2020) (13)
- USP11 controls R-loops by regulating senataxin proteostasis (2021) (11)
- Competing endogenous RNA network crosstalk reveals novel molecular markers in colorectal cancer (2018) (10)
- Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma (2021) (9)
- Study of the mechanisms of crocetin‐induced differentiation and apoptosis in human acute promyelocytic leukemia cells (2018) (9)
- Tdp1 protects from topoisomerase 1–mediated chromosomal breaks in adult zebrafish but is dispensable during larval development (2021) (7)
- Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism. (2017) (6)
- Choose your yeast strain carefully: the RAD5 gene matters (2018) (5)
- A mechanism for oxidative damage repair at gene regulatory elements (2022) (4)
- Gene of the month: NKX3.1 (2022) (4)
- Increased genomic instability following treatment with direct acting anti-hepatitis C virus drugs (2018) (4)
- Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer (2021) (4)
- Apurinic/Apyrimidinic Endonuclease 2 (APE2): An ancillary enzyme for contextual base excision repair mechanisms to preserve genome stability. (2021) (4)
- UVA‐induced carbon‐centred radicals in lightly pigmented cells detected using ESR spectroscopy (2018) (4)
- DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat (2021) (3)
- Building Bridges through Science (2017) (3)
- TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts (2020) (3)
- High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice (2021) (3)
- Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan. (2016) (2)
- SMN-deficient cells exhibit increased ribosomal DNA damage (2022) (2)
- Role of Protein Linked DNA Breaks in Cancer. (2017) (2)
- Studying TDP1 Function in DNA Repair. (2018) (2)
- Autosomal recessive ataxias due to defects in DNA repair (2015) (2)
- Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease (2022) (2)
- APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks (2008) (1)
- High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes (2023) (1)
- Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma Gene editing of ceRNA in Hepatocellular Carcinoma (2018) (1)
- CORM-3 induces DNA damage through Ru(II) binding to DNA (2022) (1)
- A role for Rad5 in ribonucleoside monophosphate (rNMP) tolerance (2021) (1)
- Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer (2021) (1)
- Nanomedicines targeting the Inflammasome as a promising therapeutic approach for cell senescence. (2022) (1)
- Faculty Opinions recommendation of Oncometabolites suppress DNA repair by disrupting local chromatin signalling. (2020) (0)
- and Keith Chromosomal DNA Strand Breaks Involved in the Cellular Response to APLF ( C 2 orf 13 ) Is a Novel Human Protein (2007) (0)
- Editorial: Genomic Instability and Neurodegeneration (2022) (0)
- Faculty Opinions recommendation of The mechanism of eukaryotic CMG helicase activation. (2019) (0)
- Faculty Opinions recommendation of Genome organization drives chromosome fragility. (2019) (0)
- DNA Damage Response Pathways in Cancer Predisposition and Progression (2015) (0)
- Faculty Opinions recommendation of Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. (2019) (0)
- Faculty Opinions recommendation of Nucleolar RNA polymerase II drives ribosome biogenesis. (2020) (0)
- AUTHOR'S CORRECTION APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks (2008) (0)
- Abstract 2512: BRCA1 and BRCA2 mutations and its clinical relevance among egyptian breast cancer women (2021) (0)
- Abstract 1049: Modulating the polymorphic UGT1A1 gene to enhance camptothecin anti-colorectal effect (2022) (0)
- Choose your yeast strain carefully: the RAD5 gene matters (2018) (0)
- Impact of circ-0000221 in the Pathogenesis of Hepatocellular via Modulation of miR-661–PTPN11 mRNA Axis (2022) (0)
- Decision letter: Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons (2019) (0)
- Oxidative DNA damage and repair at non-coding regulatory regions. (2023) (0)
- Abstract LB-323: Comparative miRNA microarray profiling indicates miR-363 promotes chemoresistance in ovarian cancer cells by targeting the Hippo member, LATS2 (2017) (0)
- Faculty Opinions recommendation of RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops. (2020) (0)
- Faculty Opinions recommendation of FAM111A protects replication forks from protein obstacles via its trypsin-like domain. (2020) (0)
- Genome-wide association study for systemic lupus erythematosus in an egyptian population (2022) (0)
- Gold nanoparticles: an optical biosensor for the direct RNA quantification for cancer, neurological disorders and hepatitis C virus diagnosis (2018) (0)
- Faculty Opinions recommendation of A genetic map of the response to DNA damage in human cells. (2020) (0)
- Faculty Opinions recommendation of CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. (2019) (0)
- a novel human protein involved in the cellular response to chromosomal DNA strand breaks (2019) (0)
- Oculomotor Apraxia 1 Single-Strand Break Repair in Ataxia Defective DNA Ligation during Short-Patch (2014) (0)
- NOVEL DRUG TARGETS TO AUGMENT TEMOZOLOMIDE SENSITIVITY IN HIGH-GRADE BRAIN TUMOURS (2018) (0)
- Chromosomal DNA Strand Breaks Involved in the Cellular Response to APLF (C2orf13) Is a Novel Human Protein (2014) (0)
- Faculty Opinions recommendation of Repeat expansions confer WRN dependence in microsatellite-unstable cancers. (2020) (0)
- C 2 orf 13 ) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks (2019) (0)
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What Schools Are Affiliated With Sherif El-Khamisy?
Sherif El-Khamisy is affiliated with the following schools:
