Shigeki Miyamoto
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Computer Science
Shigeki Miyamoto's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Shigeki Miyamoto's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. (1995) (1760)
- Calcium movements, distribution, and functions in smooth muscle. (1997) (815)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Molecular Linkage Between the Kinase ATM and NF-κB Signaling in Response to Genotoxic Stimuli (2006) (542)
- Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress (2003) (496)
- The &dgr;C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure (2003) (479)
- Autoregulation of I kappa B alpha activity. (1994) (407)
- A nuclear export signal in the N-terminal regulatory domain of IκBα controls cytoplasmic localization of inactive NF-κB/IκBα complexes (2000) (370)
- Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II (2008) (322)
- Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. (2003) (302)
- MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. (2010) (293)
- Rel/NF-kappa B/I kappa B story. (1995) (262)
- Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation (2003) (257)
- Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition. (2014) (244)
- PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress (2006) (228)
- Nuclear initiated NF-κB signaling: NEMO and ATM take center stage (2011) (224)
- DNA damage‐dependent NF‐κB activation: NEMO turns nuclear signaling inside out (2012) (221)
- Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. (2013) (207)
- Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B. (1994) (194)
- ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. (2010) (193)
- Initiation and Transduction of Stretch-induced RhoA and Rac1 Activation through Caveolae (2003) (190)
- Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy (2015) (187)
- Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy (2014) (181)
- Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines (1994) (176)
- The PEST Domain of IκBα Is Necessary and Sufficient forin Vitro Degradation by μ-Calpain* (1999) (173)
- Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes* (2013) (170)
- NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. (2000) (169)
- A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes. (2000) (164)
- Augmented acetylcholine‐induced, Rho‐mediated Ca2+ sensitization of bronchial smooth muscle contraction in antigen‐induced airway hyperresponsive rats (1999) (156)
- Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS. (2001) (152)
- Bortezomib-Resistant Nuclear Factor-κB Activity in Multiple Myeloma Cells (2008) (147)
- Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II &dgr; Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling (2018) (145)
- Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation. (1994) (135)
- RhoA/Rho Kinase Up-regulate Bax to Activate a Mitochondrial Death Pathway and Induce Cardiomyocyte Apoptosis* (2007) (135)
- HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection (2015) (132)
- A Cytosolic ATM/NEMO/RIP1 Complex Recruits TAK1 To Mediate the NF-κB and p38 Mitogen-Activated Protein Kinase (MAPK)/MAPK-Activated Protein 2 Responses to DNA Damage (2011) (128)
- Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells (1998) (124)
- Many faces of NF-κB signaling induced by genotoxic stress (2007) (123)
- The Zinc Finger Domain of NEMO Is Selectively Required for NF-κB Activation by UV Radiation and Topoisomerase Inhibitors (2002) (116)
- DEAD-box helicase DP103 defines metastatic potential of human breast cancers. (2014) (109)
- Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells (2010) (107)
- Postrepression Activation of NF-κB Requires the Amino-Terminal Nuclear Export Signal Specific to IκBα (2001) (105)
- Focal Adhesion Kinase as a RhoA-activable Signaling Scaffold Mediating Akt Activation and Cardiomyocyte Protection* (2008) (105)
- Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue (2009) (105)
- PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart (2010) (103)
- Immunoregulatory roles of versican proteolysis in the myeloma microenvironment. (2016) (97)
- Pim-1 Kinase Protects Mitochondrial Integrity in Cardiomyocytes (2010) (94)
- Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis (2018) (90)
- SUMO and NF-κB ties (2007) (87)
- RhoA protects the mouse heart against ischemia/reperfusion injury. (2011) (86)
- Coordinate modulation of Sp1, NF‐kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation (2000) (85)
- CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis. (2018) (82)
- Location Matters: Clarifying the Concept of Nuclear and Cytosolic CaMKII Subtypes (2011) (80)
- S1P1 Receptor Localization Confers Selectivity for Gi-mediated cAMP and Contractile Responses* (2008) (78)
- Many faces of NF-kappaB signaling induced by genotoxic stress. (2007) (77)
- Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals. (2016) (77)
- TPL2 kinase regulates the inflammatory milieu of the myeloma niche. (2014) (77)
- Induction of a pro‐apoptotic ATM–NF‐κB pathway and its repression by ATR in response to replication stress (2008) (77)
- NF-κB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage (2007) (76)
- Akt-mediated Cardiomyocyte Survival Pathways Are Compromised by Gαq-induced Phosphoinositide 4,5-Bisphosphate Depletion* (2003) (72)
- Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation (2015) (70)
- NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress. (2011) (69)
- Nuclear and mitochondrial signalling Akts in cardiomyocytes. (2008) (67)
- Different pathways of calcium sensitization activated by receptor agonists and phorbol esters in vascular smooth muscle (1993) (66)
- Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer (2017) (64)
- Cardiomyocyte calcium and calcium/calmodulin-dependent protein kinase II: friends or foes? (2004) (64)
- Xestospongin C, a selective and membrane‐permeable inhibitor of IP3 receptor, attenuates the positive inotropic effect of α‐adrenergic stimulation in guinea‐pig papillary muscle (2000) (63)
- Enhanced G2-M Arrest by Nuclear Factor-κB-Dependent p21waf1/cip1 Induction (2005) (63)
- Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis (2019) (61)
- Ca2+ Dysregulation Induces Mitochondrial Depolarization and Apoptosis (2005) (61)
- Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha. (2001) (59)
- Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma (2008) (58)
- RelA life and death decisions. (2004) (57)
- Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo1 (2008) (56)
- PLCε, PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart (2013) (56)
- Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway. (2005) (55)
- Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation. (2015) (54)
- Novel approaches in anaplastic thyroid cancer therapy. (2014) (51)
- Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload (2019) (49)
- CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α. (2017) (49)
- Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea (1990) (49)
- Revisited and Revised: Is RhoA Always a Villain in Cardiac Pathophysiology? (2010) (46)
- Autophagy and cardiac aging (2019) (46)
- Microscale functional cytomics for studying hematologic cancers. (2012) (43)
- Neoplastic transformation of mouse mammary epithelial cells by in vitro exposure to N-methyl-N-nitrosourea. (1988) (43)
- YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity (2018) (42)
- SUMO and NF-kappaB ties. (2007) (42)
- Induction of AP-1 activity by perillyl alcohol in breast cancer cells. (1999) (42)
- RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes. (2018) (41)
- Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle (2014) (40)
- Inflammation in non-ischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling. (2019) (40)
- MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells. (2015) (39)
- KB-R7943, a Na+/Ca2+ exchange inhibitor, does not suppress ischemia/reperfusion arrhythmias nor digitalis arrhythmias in dogs. (2002) (38)
- Gαq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Gαq mediated hypertrophy (2006) (37)
- Mitophagy as a Protective Mechanism against Myocardial Stress. (2017) (37)
- Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer. (2013) (37)
- Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation. (2011) (37)
- Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs. (2005) (37)
- Group B Streptococcal β-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function (2008) (35)
- Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells. (1998) (35)
- Incidence of c-Ki-ras activation in N-methyl-N-nitrosourea-induced mammary carcinomas in pituitary-isografted mice. (1992) (34)
- Calcium-Dependent Regulation of NEMO Nuclear Export in Response to Genotoxic Stimuli (2006) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Rapid formation of hepatic organoid in collagen sponge by rat small hepatocytes and hepatic nonparenchymal cells. (2003) (32)
- A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation (2014) (32)
- Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice. (1983) (32)
- Regulation of Constitutive p50/c-Rel Activity via Proteasome Inhibitor-Resistant IκBα Degradation in B Cells (2004) (32)
- Enhanced G2-M arrest by nuclear factor-{kappa}B-dependent p21waf1/cip1 induction. (2005) (31)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Expanded Nuclear Roles for IκBs (2004) (31)
- PIDD: A Switch Hitter (2005) (31)
- NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells. (2006) (31)
- Acetyl-l-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network (2014) (30)
- Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. (2014) (30)
- IKKβ Regulates the Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation in MCF-7 Breast Cancer Cells (2011) (30)
- A Switch in Distinct IκBα Degradation Mechanisms Mediates Constitutive NF-κB Activation in Mature B Cells1 (2000) (30)
- Ubiquitylation of nuclear receptors: new linkages and therapeutic implications. (2015) (30)
- Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection. (2017) (29)
- Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis. (1994) (29)
- Evaluating mitochondrial autophagy in the mouse heart. (2016) (28)
- Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma (2017) (28)
- Cellular and Molecular Responses to Topoisomerase I Poisons: Exploiting Synergy for Improved Radiotherapy (2000) (27)
- Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling. (2015) (26)
- A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells. (2004) (25)
- SiglecF(HI) Marks Late‐Stage Neutrophils of the Infarcted Heart: A Single‐Cell Transcriptomic Analysis of Neutrophil Diversification (2021) (25)
- Immunosuppressant FK506 Activates NF-κB through the Proteasome-mediated Degradation of IκBα (1999) (25)
- PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells (2017) (25)
- Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma (2015) (24)
- Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia (2019) (23)
- Negative inotropic effect of endothelin-1 in the mouse right ventricle. (2000) (21)
- Nuclear Factor-κB Dimer Exchange Promotes a p21waf1/cip1 Superinduction Response in Human T Leukemic Cells (2006) (21)
- CYLD: a DUB with many talents. (2007) (20)
- Transfection of activated Ha-ras protooncogenes causes mouse mammary hyperplasia. (1990) (20)
- Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. (2004) (20)
- Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells. (2002) (19)
- Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy. (2006) (19)
- Pituitary-isografted mice are highly susceptible to MNU-induced mammary carcinogenesis irrespective of the level of alveolar differentiation. (1994) (18)
- Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. (2009) (17)
- Covalent Modification of the NF-κB Essential Modulator (NEMO) by a Chemical Compound Can Regulate Its Ubiquitin Binding Properties in Vitro * (2014) (16)
- Cytochrome P450 Expression of Cultured Rat Small Hepatocytes after Long-Term Cryopreservation (2006) (16)
- NF-kappaB is essential for induction of pro-inflammatory cytokine genes by filarial parasitic sheath proteins. (2000) (15)
- IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation* (2015) (15)
- The Addition of Bevacizumab (B) to Lenalidomide and Low Dose Dexamethasone Does Not Significantly Increase Response in Relapsed or Refractory Multiple Myeloma (NCI#7317). (2009) (15)
- Phase II Trial of Bevacizumab Combined with Low Dose Dexamethasone and Lenalidomide (BEV/REV/DEX) for Relapsed or Refractory Myeloma (MM). (2007) (14)
- Expression of cytochrome P450 enzymes in hepatic organoid reconstructed by rat small hepatocytes (2005) (13)
- A PAR-SUMOnious mechanism of NEMO activation. (2009) (12)
- Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma (2016) (12)
- Epithelial cells release proinflammatory cytokines and undergo c-myc-induced apoptosis on exposure to filarial parasitic sheath protein-Bcl2 mediates rescue by activating c-H-ras (2000) (12)
- Effect of staurosporine on the induction of actin/gelsolin in PMA-treated HL-60 cells. (1990) (11)
- Effect of the sarcolemmal K(ATP) channel blocker HMR1098 on arrhythmias induced by programmed electrical stimulation in canine old myocardial infarction model: comparison with glibenclamide. (2003) (11)
- TAK-ling IKK Activation: “Ub” the Judge (2010) (11)
- QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide. (2000) (10)
- Inhibition of IκBα Nuclear Export as an Approach to Abrogate Nuclear Factor-κB–Dependent Cancer Cell Survival (2005) (10)
- IκBα deficiency imposes a fetal phenotype to intestinal stem cells (2020) (10)
- Cellular redox status determines sensitivity to BNIP3-mediated cell death in cardiac myocytes. (2015) (10)
- NF-κB Activation by Camptothecin (2000) (10)
- MAP3K8 kinase regulates myeloma growth by cell‐autonomous and non‐autonomous mechanisms involving myeloma‐associated monocytes/macrophages (2013) (10)
- Hormones, Cell Proliferation, and Mammary Carcinogenesis (1992) (10)
- Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IκBα degradation in B cells (2005) (10)
- Slowing Na+ channel inactivation prolongs QT interval and aggravates adrenaline-induced arrhythmias. (2001) (9)
- Inhibition of IkappaBalpha nuclear export as an approach to abrogate nuclear factor-kappaB-dependent cancer cell survival. (2005) (8)
- [43] Ultraviolet cross-linking of DNA binding proteins (1995) (7)
- A Switch in Distinct I kBa Degradation Mechanisms Mediates Constitutive NF-kB Activation in Mature B Cells (2000) (7)
- Inhibitory effects of pre-ischemic and post-ischemic treatment with FR 168888, a Na+/H+ exchange inhibitor, on reperfusion-induced ventricular arrhythmias in anesthetized rat. (2002) (7)
- Changes in thymidine kinase activity during differentiation of HL-60 leukemic cells. (1987) (7)
- A mechanistic insight into a proteasome-independent constitutive inhibitor κ B α (I κ B α ) degradation and nuclear factor κ B (NF- κ B) activation pathway in WEHI-231 B-cells (2004) (6)
- Does Cl-/HCO3- exchange play an important role in reperfusion arrhythmias in rats? (2003) (6)
- Drp1 and Mitochondrial Autophagy Lend a Helping Hand in Adaptation to Pressure Overload. (2016) (6)
- Quantification of Cellular NEMO Content and Its Impact on NF-κB Activation by Genotoxic Stress (2015) (6)
- Synergistic Co-Targeting of BTK and BCL2 in Mantle Cell Lymphoma (2015) (6)
- Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger (2021) (6)
- ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ (2021) (6)
- A switch in distinct I kappa B alpha degradation mechanisms mediates constitutive NF-kappa B activation in mature B cells. (2000) (5)
- CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein (2018) (5)
- Hormone-Dependent Activation of c-Ki-ras in N-Methyl-N-Nitrosourea (MNU)-Induced Mouse Mammary Tumors (1992) (5)
- Tight coupling between the rate of rise of Ca2+ transient and peak twitch contraction in guinea-pig papillary muscle. (1999) (5)
- Immunosuppressant FK506 activates NF-kappaB through the proteasome-mediated degradation of IkappaBalpha. Requirement for Ikappabalpha n-terminal phosphorylation but not ubiquitination sites. (1999) (5)
- CD14‐DEPENDENT ACTIVATION OF NF‐κB BY FILARIAL PARASITIC SHEATH PROTEINS (2002) (5)
- A new alpha in line between KRAS and NF-κB activation? (2013) (5)
- Identifying post-translational modifications of NEMO by tandem mass spectrometry after high affinity purification. (2013) (5)
- Bone marrow stromal cells transcriptionally repress ESR1 but cannot overcome constitutive ESR1 mutant activity. (2019) (4)
- Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling (2020) (4)
- Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IkappaBalpha degradation in B cells. (2005) (4)
- Expanding NFκB and SUMO ties (2011) (3)
- The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells (2022) (3)
- Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription (2022) (3)
- Block of Na exchangers on ischemia induced arrhythmias (2000) (3)
- IκBα Nuclear Export Enables 4-1BB–Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity (2020) (3)
- Species- and temperature-dependency of the decrease in myofilament Ca2+ sensitivity induced by beta-adrenergic stimulation. (2001) (3)
- Targeting apoptotic signalling pathway and pro‐inflammatory cytokine expression as therapeutic intervention in TPE induced lung damage (2003) (2)
- A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. (2022) (2)
- MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice (Journal of Clinical Investigation (2010) 120, 8, (2805-2816) DOI: 10.1172/JCI43008) (2010) (2)
- Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination (2019) (2)
- CD14-dependent activation of NF-kappaB by filarial parasitic sheath proteins. (2002) (2)
- Dissecting NF-κB signaling induced by genotoxic agents via genetic complementation of NEMO-deficient 1.3E2 cells. (2015) (2)
- Chemical-Carcinogen-Induced Transformation of Primary Cultures of Mouse Mammary Epithelial Cells Grown inside Collagen Gels (2000) (1)
- NLRP3 Inflammasome Products IL‐1beta and IL‐18 Have A Direct Effect on Cardiomyocytes (2020) (1)
- RhoA induces mitophagy through PINK1 stabilization to confer cardioprotection (2020) (1)
- Angiogenic Blockade with Bevacizumab Does Not Increase Response to Lenalidomide and Low Dose Dexamethasone in Relapsed or Refractory Myeloma (2012) (1)
- [Hexokinase 2 mediated cellular protection: interaction with Akt/mTORC1 to regulate mitochondrial protection and autophagy]. (2017) (1)
- Bortezomib Resistant Constitutive NF-κB Activation in Mantle Cell Lymphoma. (2007) (1)
- Two Cases of Dedifferentiated Liposarcoma of the Retroperitoneum Referencing Immunohistochemical Studies (2009) (1)
- ErratumNuclear Export of the NF-κB Inhibitor IκBα Is Required for Proper B Cell and Secondary Lymphoid Tissue Formation (2011) (1)
- EXTENDED RESECTION FOR AN ADVANCED GASTRIC CANCER CASE WITH SIMULTANEOUS METASTATIC GALLBLADDER CANCER SUCCESSFULLY TREATED BY RADICAL SURGERY AND POSTOPERATIVE CHEMOTHERAPY: 3 YEARS SURVIVAL WITH NON-RECURRENCE (2009) (1)
- Alcohol Inhibits a Calcium-Dependent Constitutive Nuclear Factor-K B Pathway (2005) (1)
- Abstract 18574: Mitochondrial Reprogramming By Camkiiδ Underlies Gq-induced Cardiomyopathy (2012) (1)
- Ultraviolet cross-linking of DNA binding proteins. (1995) (1)
- Versican (VCAN) Proteolysis Predicts T-Cell Infiltration in Myeloma Bone Marrow Post- Autologous Stem Cell Transplant (ASCT) (2017) (1)
- Versican proteolysis as a key regulator of CD8+ T-cell infiltration in colorectal cancer. (2017) (1)
- Abstract 14162: NLRP3 Inflammasome Activation Initiated Through Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKIIδ) Signaling in Cardiomyocytes is Essential for Pressure Overload-Induced Adverse Cardiac Remodeling (2018) (1)
- A nuclear export signal in the N-terminal regulatory domain of I k B a controls cytoplasmic localization of inactive NF- k B y I k B a complexes (2000) (0)
- Inflammation In Vivo NEMO Modulates TLR Signaling and Cutting Edge: K63-Linked Polyubiquitination of (2012) (0)
- Abstract 16738: Hk-II Regulates Autophagy Under Glucose Deprivation Through TORC1 Inhibition in Cardiomyocytes (2012) (0)
- Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution (2021) (0)
- Initial Results of an Ex Vivo Microfluidic Cis -Coculture Csra to Predict Response for Myeloma Patients (2014) (0)
- Cardiomyocyte NLRP3 Contributes to the Cardiac Inflammatory Response (2021) (0)
- Molecular Pathways That Determine the Activation State of Macrophages within the Myeloma Niche (2012) (0)
- Abstract P185: Cardiac Characterization of Phlpp1 Knockout Mice: A Novel Phosphatase to Terminate Akt Signaling (2011) (0)
- Timelapse viability assay to detect division and death of primary multiple myeloma cells in response to drug treatments with single cell resolution. (2022) (0)
- Ectopic CH60 mediates HAPLN1-induced cell survival signaling in multiple myeloma (2022) (0)
- Abstract 313: Sphingosine-1-Phosphate and RhoA Signaling Regulate Dynamin-Related Protein 1 and Cardiac Mitochondrial Fission (2017) (0)
- Akt mediates cardioprotection through phosphorylation of mitochondrial hexokinase-II (2007) (0)
- Incidence of cKi-ras Activation in 7 V-Methyl-. / V-nitrosourea-indiicedMammary Carcinomas in Pituitary-isografted Mice 1 (2006) (0)
- Abstract 17464: RhoA Signaling Stabilizes PINK1 and Induces Mitophagy in Cardiomyocytes (2017) (0)
- Mechanisms and Models for Elucidating the Cardiac Effects of Sphingosine 1‐Phosphate (S1P) (2013) (0)
- Identification of a 38-kDa protein (p38) in HL-60 leukemic cells as a truncated actin. (1991) (0)
- Abstract 1377: PHLPP, a Novel Akt Phosphatase, Expressed and is Regulated in Cardiomyocytes (2006) (0)
- Role of Autophagy in Cardiac Physiology and Pathophysiology (2018) (0)
- Abstract 2165: Identification of a novel pathway of castrate resistant prostate cancer (CRPCa) growth (2011) (0)
- RhoA signaling in cardiomyocyte survival and apoptosis (2007) (0)
- Abstract 1169: TPL2 kinase regulates the inflammatory milieu of the myeloma niche (2014) (0)
- RhoA regulates mitochondrial quality control through mitophagy and mitochondrial fission (2018) (0)
- Inhibitors of Na+/H+ exchanger or Na+/Ca+ exchanger (2000) (0)
- RhoA mediated transcriptional pathways in tumor cell growth (2018) (0)
- Correction for Romero et al., “Pseudorabies Virus Infection Results in a Broad Inhibition of Host Gene Transcription” (2022) (0)
- A exchange inhibitor, KB-R7943, on digitalis and ischemia-reperfusion arrhythmia models (2001) (0)
- Evidence for Unique Calmodulin-Dependent Nuclear Factor- (cid:1) B Regulation in WEHI-231 B Cells (2001) (0)
- Autoregulation of IicBa activity (2005) (0)
- MICROFLUIDIC SUSPENSION CELL CULTURE PLATFORM FOR STUDYING POPULATION HETEROGENEITY IN NF-KB SIGNALING (2012) (0)
- Inducible cardiac‐specific RhoA‐expression protects against ischemia/reperfusion injury in mouse hearts (2010) (0)
- Preneoplastic Event in Mouse Mammary Carcinogenesis Induced In Vitro by N-Methyl-N-Nitrosourea (2003) (0)
- Abstract 16870: Dissociation of Mitochondrial HK-II Triggers Mitochondria Specific Autophagy (2014) (0)
- Abstract 3197: Functional microscale cell-based systems for studying hematologic cancers in complex microenvironments (2012) (0)
- Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2 + / Calmodulin-Dependent Protein Kinase II Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling Permalink (2018) (0)
- HAPLN1 confers multiple myeloma cell resistance to several classes of therapeutic drugs (2022) (0)
- DMD # 8342 1 Cytochrome P 450 Expression of Cultured Rat Small Hepatocytes After Long-Term Cryopreservation (2006) (0)
- Microfluidic Platform Enabling Primary Multiple Myeloma Mono- and Cis-Co-Culture Analysis (2012) (0)
- Abstract 424: Activation of the S1P3 Receptors is Responsible for S1P-mediated RhoA Activation and Cardioprotection (2015) (0)
- GPCRs are regulators of MRTF‐A and YAP mediated CCN1 expression (1066.4) (2014) (0)
- IN THE SPOTLIGHT A New Alpha in Line Between KRAS and NF-kB Activation? (2013) (0)
- ATPase Inhibitor Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ (2021) (0)
- S1P receptor localization confers selectivity for Gi mediated signaling pathways (2008) (0)
- Plasmids and Shrna (0)
- Nuclear export of NF-κB inhibitor, IκBα, is crucial for T cell function (IRM12P.644) (2015) (0)
- Abstract 32: Suppression of medical radiation DNA damage in cancer susceptible and normal humans using a new aminothiol radioprotector (2014) (0)
- Regulation of glioblastoma tumor growth and stem cell properties through Gα12: an upstream player in YAP signaling (2020) (0)
- P1797Calcium/calmodulin-dependent protein kinase II (CaMKII) initiates inflammation, inflammasome activation and immune cell infiltration in response to pressure overload through signaling in cardiomyocyte (2018) (0)
- Cardiomyocyte‐generated Monocyte Chemoattractant Protein 1 Contributes to Cardiac Inflammation During Adverse Remodeling in Pressure Overload (2020) (0)
- Enhanced IKBot Degradation Is Responsible for Constitutive NF-KB Activity in Mature Murine B-Cell Lines (0)
- Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes. (2013) (0)
- Postrepression Activation of NF- k B Requires the Amino-Terminal Nuclear Export Signal Specific to I k B a (2001) (0)
- Abstract P290: RhoA Protects Against Myocardial Ischemia/Reperfusion Injury (2011) (0)
- Award Number: W81XWH-05-1-0295 TITLE: Characterization of a SUMO Ligase that is Essential for DNA Damage-Induced NF-Kappa B Activation (2007) (0)
- Biochemical studies of the differentiation of HL-60 cells into monocytes by either IFN, VIT, D/sub 3/ or TPA (1987) (0)
- The Critical Role of Iκbα Dependent Nuclear Export of NF-κb in B-Cell Development. (2008) (0)
- Abstract 160: Cardiomyocyte CaMKII Mediates Expression of Pro-inflammatory Chemokines and Cytokines, Macrophage Infiltration and Cardiac Remodeling in Response to Pressure Overload (2017) (0)
- Phase II Trial of Bortezomib Combined with Weekly Doxorubicin and Oral Dexamethasone for Relapsed or Refractory Multiple Myeloma (MM): Effect of NF-κB Activation on Response. (2006) (0)
- Characterization of a SUMO Ligase that is Essential for DNA Damage-Induced NF-Kappa B Activation (2008) (0)
- Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Signaling in Cardiomyocytes Initiates Inflammatory Gene Expression, Inflammasome Activation and Macrophage Accumulation Leading to Adverse Cardiac Remodeling in Response to Pressure Overload (2018) (0)
- Abstract 19297: Cardiac Specific Deletion of Mcl-1 Leads to Impaired Autophagy and Rapid Development of Heart Failure (2012) (0)
- Title Myocardin-related transcription factor A and Yes-associated protein exert dual control in G protein-coupled receptor-and RhoA-mediated transcriptional regulation and cell (2015) (0)
- Analyze the SUMOylation of IKK γ/NEMO During Genotoxic Stress. (2021) (0)
- Exploring a Link Between NF-KB and G2/M Cell Cycle Arrest in Breast Cancer Cells (2004) (0)
- Regulation of iNOS by autocrine action of prostaglandins in the resident macrophage in the intestinal muscle (2000) (0)
- Splicing and Dicing: A Deeper Dive Into CaMKIIδ and Cardiac Inflammation. (2022) (0)
- Mitochondria from Oxidative Stress in the Heart PLC{varepsilon}, PKD1, and SSH1L Transduce RhoA Signaling to Protect (2013) (0)
- S1P induces CCN1 expression through RhoA/MRTF‐a activation and protects cardiomyocytes against cell death (2012) (0)
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What Schools Are Affiliated With Shigeki Miyamoto?
Shigeki Miyamoto is affiliated with the following schools:
