Shigeki Shibahara
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Molecular Biology
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Biology
Shigeki Shibahara's Degrees
- PhD Biology University of Tokyo
- Masters Biochemistry Kyoto University
- Bachelors Chemistry Kyoto University
Why Is Shigeki Shibahara Influential?
(Suggest an Edit or Addition)Shigeki Shibahara's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Melanin pigmentation in mammalian skin and its hormonal regulation. (2004) (1738)
- Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. (2000) (598)
- Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene (2002) (575)
- Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1 (2001) (490)
- Cloning and expression of cDNA for rat heme oxygenase. (1985) (440)
- Tenascin: cDNA cloning and induction by TGF‐beta. (1988) (418)
- Isolation and sequence analysis of the human corticotropin‐releasing factor precursor gene. (1983) (399)
- Functional Analysis of Microphthalmia-associated Transcription Factor in Pigment Cell-specific Transcription of the Human Tyrosinase Family Genes* (1997) (374)
- Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity. (1995) (351)
- Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene (1994) (350)
- Induction of Melanocyte-specific Microphthalmia-associated Transcription Factor by Wnt-3a* (2000) (326)
- Human heme oxygenase cDNA and induction of its mRNA by hemin. (1988) (309)
- Bach1 Functions as a Hypoxia-inducible Repressor for the Heme Oxygenase-1 Gene in Human Cells* (2003) (260)
- The physiological significance of heme oxygenase. (1988) (242)
- HLF/HIF‐2α is a key factor in retinopathy of prematurity in association with erythropoietin (2003) (232)
- Microphthalmia‐associated transcription factor interacts with LEF‐1, a mediator of Wnt signaling (2002) (228)
- Cloning and sequence analysis of cDNA for rat corticotropin‐releasing factor precursor (1985) (218)
- Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer (2004) (218)
- Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells. (1989) (212)
- Cloning and expression of cDNA encoding mouse tyrosinase. (1986) (197)
- Functional analysis of cDNAs for two types of human heme oxygenase and evidence for their separate regulation. (1993) (196)
- Induction of haem oxygenase-1 by nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth (1999) (193)
- Nucleotide sequence and organization of the rat heme oxygenase gene. (1987) (182)
- Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia (1993) (182)
- Human oculocutaneous albinism caused by single base insertion in the tyrosinase gene. (1989) (179)
- Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease (1997) (177)
- BRG1 Interacts with Nrf2 To Selectively Mediate HO-1 Induction in Response to Oxidative Stress (2006) (174)
- Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines. (2003) (165)
- Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation. (2001) (164)
- Cloning and sequence analysis of cDNA for ovine corticotropin-releasing factor precursor (1983) (153)
- The heme oxygenase dilemma in cellular homeostasis: new insights for the feedback regulation of heme catabolism. (2003) (151)
- Structural organization of the human heme oxygenase gene and the function of its promoter. (1989) (143)
- Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters. (2000) (138)
- Regulation of human heme oxygenase-1 gene expression under thermal stress. (1996) (137)
- Identification of a cis-acting element that is responsible for cadmium-mediated induction of the human heme oxygenase gene. (1994) (135)
- Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium. (1998) (134)
- Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene. (1996) (129)
- Expression of heme oxygenase and inducible nitric oxide synthase mRNA in human brain tumors. (1996) (123)
- Association of susceptibility to the development of lung adenocarcinoma with the heme oxygenase-1 gene promoter polymorphism (2005) (118)
- Melanocyte-specific Microphthalmia-associated Transcription Factor Isoform Activates Its Own Gene Promoter through Physical Interaction with Lymphoid-enhancing Factor 1* (2002) (115)
- Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2. (1994) (114)
- [Regulation of heme oxygenase gene expression]. (1988) (113)
- Increased expression of heme oxygenase mRNA in rat brain following transient forebrain ischemia (1994) (111)
- The Great East-Japan Earthquake and devastating tsunami: an update and lessons from the past Great Earthquakes in Japan since 1923. (2013) (110)
- Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the International Conference (Uppsala, 2003) on Heme Oxygenase. (2004) (109)
- An L1 element intronic insertion in the black-eyed white (Mitf[mi-bw]) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness. (1999) (108)
- Cloning and sequence analysis of human genomic DNA encoding gamma subunit precursor of muscle acetylcholine receptor. (1985) (104)
- Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression. (1994) (104)
- Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells. (2000) (102)
- Microphthalmia-associated transcription factor in the Wnt signaling pathway. (2003) (101)
- Expression of Heme Oxygenase Isozyme mRNAs in the Human Brain and Induction of Heme Oxygenase‐1 by Nitric Oxide Donors (1996) (97)
- Nucleotide sequence of the cDNA encoding human tyrosinase-related protein. (1990) (96)
- Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells. (1998) (93)
- Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene (1995) (93)
- A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85. (1990) (92)
- Expression of urocortin III/stresscopin in human heart and kidney. (2004) (90)
- Regulation of pigment cell-specific gene expression by MITF. (2000) (88)
- Molecular cloning of cDNA encoding a novel microphthalmia-associated transcription factor isoform with a distinct amino-terminus. (1999) (87)
- The 2011 Tohoku earthquake and devastating tsunami. (2011) (86)
- Separate regulation of heme oxygenase and heat shock protein 70 mRNA expression in the rat heart by hemodynamic stress. (1993) (85)
- Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes. (2007) (85)
- Molecular basis for the heterogeneity of human tyrosinase. (1988) (83)
- Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2. (2004) (83)
- Heme degradation and human disease: diversity is the soul of life. (2002) (83)
- A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work. (1998) (80)
- Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations. (2002) (80)
- Production and Secretion of Adrenomedullin From Glial Cell Tumors and its Effects on cAMP Production (1997) (75)
- Increased Expression of Heme Oxygenase-1 and Bilirubin Accumulation in Foam Cells of Rabbit Atherosclerotic Lesions (2001) (75)
- Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to cerebral malaria in Myanmar. (2005) (72)
- Production and Secretion of Adrenomedullin by Cultured Choroid Plexus Carcinoma Cells (1997) (71)
- Identification of a novel erythroid-specific enhancer for the ALAS2 gene and its loss-of-function mutation which is associated with congenital sideroblastic anemia (2014) (71)
- Neuroendocrine functions of melanocytes: beyond the skin-deep melanin maker. (2007) (70)
- Adrenomedullin is a novel adipokine: Adrenomedullin in adipocytes and adipose tissues (2007) (69)
- Expression of urotensin II and its receptor in adrenal tumors and stimulation of proliferation of cultured tumor cells by urotensin II (2003) (66)
- Expression of urotensin II and urotensin II receptor mRNAs in various human tumor cell lines and secretion of urotensin II-like immunoreactivity by SW-13 adrenocortical carcinoma cells (2001) (66)
- Induction of heme oxygenase by hemin in cultured pig alveolar macrophages. (1978) (66)
- Identification of a distal enhancer for the melanocyte-specific promoter of the MITF gene. (2002) (65)
- Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis. (1999) (63)
- Heme Oxygenase-2 (1995) (63)
- Expression of Adrenomedullin mRNA in the Human Brain and Pituitary (1997) (62)
- Functional analysis of the cDNA encoding human tyrosinase precursor. (1989) (62)
- Identification of a cis-regulatory element and putative trans-acting factors responsible for 12-O-tetradecanoylphorbol-13-acetate (TPA)-mediated induction of heme oxygenase expression in myelomonocytic cell lines (1993) (62)
- Induction of adrenomedullin by hypoxia in cultured human coronary artery endothelial cells (1999) (61)
- Identification of a cis-acting element that enhances the pigment cell-specific expression of the human tyrosinase gene. (1992) (61)
- Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. (1999) (61)
- Increased Secretion of Adrenomedullin from Cultured Human Astrocytes by Cytokines (2000) (59)
- Adrenomedullin in cultured human retinal pigment epithelial cells. (2000) (58)
- Structural organization of the pigment cell-specific gene located at the brown locus in mouse. Its promoter activity and alternatively spliced transcript. (1991) (58)
- Brain tumors predominantly express the neurofibromatosis type 1 gene transcripts containing the 63 base insert in the region coding for GTPase activating protein-related domain. (1991) (57)
- Hypoxia and heme oxygenases: oxygen sensing and regulation of expression. (2007) (57)
- Molecular basis of tyrosinase-negative oculocutaneous albinism. A single base mutation in the tyrosinase gene causing arginine to glutamine substitution at position 59. (1990) (56)
- Regulation of elastin synthesis in developing sheep nuchal ligament by elastin mRNA levels. (1982) (55)
- Modulation of tropoelastin production and elastin messenger ribonucleic acid activity in developing sheep lung. (1981) (55)
- Mechanism of increase of heme oxygenase activity induced by hemin in cultured pig alveolar macrophages. (1979) (54)
- Interaction of upstream stimulatory factor with the human heme oxygenase gene promoter. (1990) (54)
- Sequential activation of genes for heme pathway enzymes during erythroid differentiation of mouse Friend virus-transformed erythroleukemia cells. (1991) (54)
- Repression of Heme Oxygenase-1 Expression as a Defense Strategy in Humans (2003) (53)
- Expression of the Sox10 gene during mouse inner ear development. (2000) (53)
- Induction of heparin-binding growth-associated molecule expression in reactive astrocytes following hippocampal neuronal injury (1995) (52)
- Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells. (2001) (52)
- Induction of Adrenomedullin During Hypoxia in Cultured Human Glioblastoma Cells (2000) (51)
- Suppression of Heme Oxygenase‐1 mRNA Expression by Interferon‐γ in Human Glioblastoma Cells (1999) (51)
- cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. (1996) (51)
- Altered expression of retinoblastoma protein‐interacting zinc finger gene, RIZ, in human leukaemia (2002) (51)
- Identification of a nuclear protein that constitutively recognizes the sequence containing a heat-shock element. Its binding properties and possible function modulating heat-shock induction of the rat heme oxygenase gene. (1993) (49)
- Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha. (2003) (47)
- Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors. (1997) (47)
- Regional difference in induction of heme oxygenase-1 protein following rat transient forebrain ischemia (1996) (46)
- The monoclonal antibodies TMH-1 and TMH-2 specifically bind to a protein encoded at the murine b-locus, not to the authentic tyrosinase encoded at the c-locus. (1991) (44)
- Hypoxia reduces the expression of heme oxygenase‐2 in various types of human cell lines (2006) (43)
- OTX2 regulates expression of DOPAchrome tautomerase in human retinal pigment epithelium. (2003) (43)
- Expression of heme oxygenase-1 is repressed by interferon-gamma and induced by hypoxia in human retinal pigment epithelial cells. (2004) (41)
- Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter. (1989) (41)
- Cloning and functional analysis of ascidian Mitf in vivo: insights into the origin of vertebrate pigment cells (2003) (41)
- Mitf functions as an in ovo regulator for cell differentiation and proliferation during development of the chick RPE. (2009) (41)
- Dynamic regulation of the human dopachrome tautomerase promoter by MITF, ER-alpha and chromatin remodelers during proliferation and senescence of human melanocytes. (2005) (39)
- Positive and negative regulation of the human heme oxygenase-1 gene expression in cultured cells. (1999) (39)
- Transcriptional regulation of a plasminogen activator gene by cyclic AMP in a homologous cell-free system. Involvement of cyclic AMP-dependent protein kinase in transcriptional control. (1988) (37)
- Melanin-concentrating hormone in human and rat. (1995) (37)
- Functional expression of heme oxygenase-1 in human differentiated epidermis and its regulation by cytokines. (2009) (37)
- Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF. (2006) (36)
- Expression of heme oxygenase gene in rat and human liver. (1988) (36)
- Neonatal Hyperbilirubinemia in Japanese Neonates: Analysis of the Heme Oxygenase-1 Gene and Fetal Hemoglobin Composition in Cord Blood (2003) (36)
- Elastin mRNA levels during foetal development of sheep nuchal ligament and lung. Hybridization to complementary and cloned DNA. (1984) (35)
- Production and secretion of two vasoactive peptides, adrenomedullin and endothelin-1, by cultured human adrenocortical carcinoma cells (2000) (35)
- Otx2 Is Involved in the Regional Specification of the Developing Retinal Pigment Epithelium by Preventing the Expression of Sox2 and Fgf8, Factors That Induce Neural Retina Differentiation (2012) (34)
- Downstream region of the human tyrosinase-related protein gene enhances its promoter activity. (1992) (33)
- Down‐regulation of heme oxygenase‐2 is associated with the increased expression of heme oxygenase‐1 in human cell lines (2006) (33)
- Decreased expression of neurotrophin-3 mRNA in the rat hippocampus following transient forebrain ischemia (1992) (32)
- Differential control of the metal-mediated activation of the human heme oxygenase-1 and metallothionein IIA genes. (1995) (32)
- Adrenomedullin in the eye (2003) (31)
- Late-onset X-linked sideroblastic anemia following hemodialysis. (2003) (31)
- Association of susceptibility to the development of pneumonia in the older Japanese population with haem oxygenase-1 gene promoter polymorphism (2005) (30)
- Urocortins as cardiovascular peptides. (2004) (30)
- Expression of melanin-concentrating hormone receptor messenger ribonucleic acid in tumor tissues of pheochromocytoma, ganglioneuroblastoma, and neuroblastoma. (2001) (30)
- Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator. (1997) (29)
- Increased dopamine and its metabolites in SH‐SY5Y neuroblastoma cells that express tyrosinase (2003) (29)
- Tetrahydrocurcumin in combination with deferiprone attenuates hypertension, vascular dysfunction, baroreflex dysfunction, and oxidative stress in iron-overloaded mice. (2016) (28)
- Elevated levels of heme oxygenase‐1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients (1993) (28)
- Phylogeny of regulatory regions of vertebrate tyrosinase genes. (1992) (28)
- Heme oxygenase—regulation of and physiological implication in heme catabolism (1994) (27)
- Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells. (2000) (27)
- Diminished heme oxygenase-1 mRNA expression in RPE cells from diabetic donors as quantitated by competitive RT/PCR. (1997) (26)
- SOX10, in combination with Sp1, regulates the endothelin receptor type B gene in human melanocyte lineage cells (2006) (26)
- Dynamic changes in expression of heme oxygenases in mouse heart and liver during hypoxia. (2005) (26)
- Specific expression of Gsta4 in mouse cochlear melanocytes: a novel role for hearing and melanocyte differentiation (2009) (25)
- Three vasoactive peptides, endothelin-1, adrenomedullin and urotensin-II, in human tumour cell lines of different origin: expression and effects on proliferation. (2002) (25)
- Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells (2001) (25)
- Elevated adrenomedullin in the vitreous of patients with proliferative vitreoretinopathy. (1999) (25)
- A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces haem oxygenase-1 expression in human cells through a mechanism independent of hypoxia-inducible factor-1alpha. (2008) (24)
- Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells. (2001) (24)
- Increased expression of adrenomedullin mRNA in the tissues of intraocular and orbital tumors. (2000) (24)
- Prevention of cadmium accumulation in retinal pigment epithelium with manganese and zinc. (2008) (24)
- Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells. (2008) (24)
- Retinal pigment epithelial cell-based gene therapy against hemoglobin toxicity. (1998) (23)
- Molecular cloning of a cDNA coding for neurofibromatosis type 1 protein isoform lacking the domain related to ras GTPase-activating protein. (1992) (23)
- The carboxyl-terminal region of erythroid-specific 5-aminolevulinate synthase acts as an intrinsic modifier for its catalytic activity and protein stability. (2012) (22)
- Production and secretion of adrenomedullin in cultured human alveolar macrophages (1999) (22)
- Regional distribution of immunoreactive prolactin-releasing peptide in the human brain (2000) (21)
- Expression of endothelin-1 and endothelin receptors in cultured human glioblastoma cells. (2000) (21)
- Mapping of the human gene for inducible heme oxygenase to chromosome 22q12. (1994) (20)
- Suppression of cytokine-induced expression of adrenomedullin and endothelin-1 by dexamethasone in T98G human glioblastoma cells (2003) (20)
- Decreased expression of adrenomedullin during adipocyte-differentiation of 3T3-L1 cells. (2003) (20)
- Production and secretion of two vasoactive peptides, endothelin-1 and adrenomedullin, by a colorectal adenocarcinoma cell line, DLD-1. (1998) (19)
- Induction of lipocalin-type prostaglandin D synthase in mouse heart under hypoxemia. (2009) (19)
- Suppression of heme oxygenase-1 mRNA expression by interferon-gamma in human glioblastoma cells. (1999) (19)
- Molecular analysis of the DNA segments cross-hybridizable to the tyrosinase gene in patients affected with oculocutaneous albinism. (1989) (19)
- Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway (2008) (19)
- Activation of the tyrosinase gene promoter by neurofibromin. (1994) (18)
- Expression of heme oxygenase in hemopoiesis. (1988) (18)
- Germ cell-specific expression of microphthalmia-associated transcription factor mRNA in mouse testis. (2003) (18)
- New approaches for the high-level expression of human interleukin-2 cDNA in Escherichia coli. (1987) (17)
- Revisiting the March 11, 2011 earthquake and tsunami: resilience and restoration. (2012) (17)
- Mice with blunted hypoxic ventilatory response are susceptible to respiratory disturbance during hypoxia. (2006) (17)
- Identification of a composite enhancer of the human tyrosinase-related protein 2/DOPAchrome tautomerase gene. (2000) (17)
- Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma. (2001) (17)
- Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I. (1995) (16)
- Hypoxia induces erythroid‐specific 5‐aminolevulinate synthase expression in human erythroid cells through transforming growth factor‐β signaling (2009) (16)
- Role of neurofibromin in modulation of expression of the tyrosinase-related protein 2 gene. (1998) (16)
- Adrenomedullin in adipocyte differentiation of human mesenchymal stem cells. (2006) (15)
- [Molecular genetics of neurofibromatosis type 1]. (1993) (15)
- Coordinated expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 and heme oxygenase 2: evidence for a regulatory link between glycolysis and heme catabolism. (2012) (15)
- Nucleotide sequence of the putative human tyrosinase pseudogene. (1991) (15)
- Identification of mutations in the pigment cell-specific gene located at the brown locus in mouse. (2008) (15)
- Impaired development of melanoblasts in the black‐eyed white Mitfmi‐bw mouse, a model for auditory–pigmentary disorders (2012) (14)
- Sheep elastin genes. Isolation and preliminary characterization of a 9.9-kilobase genomic clone. (1984) (14)
- MAT-1, a monoclonal antibody that specifically recognizes human tyrosinase. (1995) (13)
- Dysregulated Expression of MITF in Subsets of Hepatocellular Carcinoma and Cholangiocarcinoma. (2017) (13)
- Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of adrenocortical tumors, pheochromocytomas and neuroblastomas (2002) (13)
- Production and secretion of endothelin-1 by cultured choroid plexus carcinoma cells. (1998) (13)
- Elevated immunoreactive-adrenomedullin levels in the aqueous humor of patients with uveitis and vitreoretinal disorders (2002) (13)
- Arg452 substitution of the erythroid‐specific 5‐aminolaevulinate synthase, a hot spot mutation in X‐linked sideroblastic anaemia, does not itself affect enzyme activity (2006) (13)
- Augmented chemosensitivity in black-eyed white Mitfmi-bw mice, lacking melanocytes. (2006) (13)
- Melanocytes contribute to the vasculature of the choroid. (2018) (12)
- Prostaglandin D2 induces heme oxygenase-1 mRNA expression through the DP2 receptor. (2008) (12)
- Insertion of long interspersed element‐1 in the Mitf gene is associated with altered neurobehavior of the black‐eyed white Mitfmi‐bw mouse (2014) (12)
- Functional difference of the SOX10 mutant proteins responsible for the phenotypic variability in auditory-pigmentary disorders. (2006) (11)
- Microphthalmia‐associated transcription factor is expressed in projection neurons of the mouse olfactory bulb (2015) (11)
- Identification of adipocyte differentiation-related regulatory element for adrenomedullin gene repression (ADRE-AR) in 3T3-L1 cells (2006) (11)
- Microphthalmia-associated transcription factor as the molecular target of cadmium toxicity in human melanocytes. (2014) (10)
- Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours. (1994) (10)
- Developmental regulation of elastin synthesis. (1981) (10)
- Secretion of endothelin-1 and adrenomedullin by SW-13 human adrenocortical carcinoma cells. (2000) (9)
- Production and secretion of neuropeptides by nervous system tumors (1998) (8)
- Mutations of the tyrosinase gene in oculocutaneous albinism. (1992) (8)
- Intracellular site of synthesis of microsomal heme oxygenase in pig spleen. (1980) (8)
- Functional analysis of the tyrosinase gene and brown-locus protein gene promoters. (1993) (8)
- Heme-Regulated Transcription Factor Bach1 (2002) (8)
- Induction of MITF expression in human cholangiocarcinoma cells and hepatocellular carcinoma cells by cyclopamine, an inhibitor of the Hedgehog signaling. (2016) (8)
- Implications of isoform multiplicity of microphthalmia-associated transcription factor in the pathogenesis of auditory-pigmentary syndromes. (1999) (8)
- MITF‐CM, a newly identified isoform of microphthalmia‐associated transcription factor, is expressed in cultured mast cells (2009) (8)
- Lipocalin‐type prostaglandin D synthase as a marker for the proliferative potential of melanocyte‐lineage cells in the human skin (2012) (7)
- Hypoxemia induces expression of heme oxygenase-1 and heme oxygenase-2 proteins in the mouse myocardium. (2010) (7)
- Synergistic activation of the human adrenomedullin gene promoter by Sp1 and AP-2α (2008) (7)
- Nucleotide alteration of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukemia. (2002) (7)
- Hypoxemia and attenuated hypoxic ventilatory responses in mice lacking heme oxygenase-2: evidence for a novel role of heme oxygenase-2 as an oxygen sensor. (2006) (6)
- The Upcoming 90(th) anniversary of the Tohoku Journal of Experimental Medicine. (2009) (5)
- Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells (1993) (5)
- Suppression of Cytokine-induced Expression of Endothelin-1 by Dexamethasone in Human Retinal Pigment Epithelial Cells (2004) (5)
- Differential expression of adrenomedullin and resistin in 3 T 3L 1 adipocytes treated with tumor necrosis factor-a (2003) (5)
- Molecular bases of tyrosinase-negative oculocutaneous albinism: a single base insertion or a missense point mutation in the tyrosinase gene. (2008) (4)
- Hypoxia increases endothelin-1 mRNA expression but not immunoreactive endothelin in the medium of T98G glioblastoma cells under cytokine treatment (2006) (4)
- Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes. (2010) (4)
- Transcriptional Regulation of Melanocyte Function (2007) (3)
- Microphthalmia‐associated transcription factor ensures the elongation of axons and dendrites in the mouse frontal cortex (2016) (2)
- Cloning and sequence analysis of the tyrosinase gene from a patient with tyrosinase-positive oculocutaneous albinism. (1992) (2)
- Evidence for the presence of two amino-terminal isoforms of neurofibromin, a gene product responsible for neurofibromatosis type 1. (1995) (2)
- Molecular basis of tyrosinase-negative albinism: A single base mutation in the tyrosinase gene causing the arginine to glutamine substitution at position 59 (1990) (2)
- Sensing the Soul of Science via Sendai: The Prologue to the Tenth Decade of TJEM (2010) (2)
- Partial Purification and cDNA Cloning of Human Histidine Decarboxylase (1991) (1)
- 1 Identification of the novel erythroid-specific enhancer for ALAS 2 gene and its loss-of-function mutation associated with congenital sideroblastic anemia Running heads : Disruption of GATA binding element causes CSA (2013) (1)
- Transcriptional Control of the Human Heme Oxygenase-1 Gene by Stress (1996) (1)
- 100 Years of the Tohoku Journal of Experimental Medicine, and the Tohoku Medical Megabank Project in the Japanese New Era, Reiwa. (2019) (1)
- Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitfmi-bw Mouse Lacking Melanocytes (2016) (1)
- Regulation of heme oxygenase gene expression. (1988) (1)
- [Isoform multiplicity of microphthalmia-associated transcription factor]. (1999) (0)
- Differential tissue-specific expression of neurofibromin isoform mRNAs in rat. (1996) (0)
- oxygenase-1 in murine renal medullary cells Urea and hypertonicity increase expression of heme (2016) (0)
- [ON THE OBSERVATION OF THE PARESTHESIA IN THE HYPOPHARNX]. (1963) (0)
- Beauty in the architecture of living organisms. (2008) (0)
- Physiological Implication of Induction of Heme Oxygenase-1 Gene Expression (1998) (0)
- [Heme as a signaling molecule under environmental stress]. (1999) (0)
- A Message for Young Authors: The Past 100 Years and Future of the Tohoku Journal of Experimental Medicine. (2020) (0)
- The gene expressions of tyrosinase and tyrosinase-related protein are enhanced by different cis-acting elements (1993) (0)
- Identification of the Novel Erythroid-Specific Enhancer in the First Intron of Human ALAS2 Gene; Tthe Mutation Disrupting GATA Transcription Factor-Binding Site in the Enhancer Causes X-Linked Sideroblastic Anemia (2012) (0)
- Suppression of Erythroid-Specific 5-Aminolevulinate Synthase Using Short-Interfering RNA Alters Iron Metabolism and Inhibits Terminal Differentiation of Human Erythroleukemia Cells. (2004) (0)
- The Retinal Pigment Epithelial Cell Differentiation and Cell Marker Expression Following Cryopreservation at -80°C and under Liquid Nitrogen at -196°C (1999) (0)
- [Heme oxygenase-1: for whom is its expression suppressed?]. (2003) (0)
- Expression of Heme Oxygenase and Inducible Nitric Oxide Synthase mRNA in a Human Glioblastoma Cell Line (1998) (0)
- Transgenic rd mice harboring axokine gene by Rpe65 gene promoter does not rescue photoreceptor degeneration. (2003) (0)
- Expression of Heme Oxygenase-1 mRNA in Human Brain Tumors (1996) (0)
- PSMA7, a subunit of proteasome, interacts with heme oxygenase-2 (2007) (0)
- Hypoxia Induces Hemoglobin Production in Human Erythroleukemia Cells by Increasing the Secretion of Transforming Growth Factor -β1 and the Expression of Mitoferrin. (2006) (0)
- Detection of mouse tyrosinase with a monoclonal antibody MAT-1 against human tyrosinase. (1996) (0)
- human abdominal and femoral adipose tissue Catecholamine effects on lipolysis and blood flow in (2015) (0)
- Gene analysis in patients with tyrosinase activity-negative albinism (1990) (0)
- General presentation A-1 MOLECULAR ANALYSIS OF ALPHA-THARASSEMIA IN NEPAL: CORRELATION WITH MALARIA ENDEMICITY (2010) (0)
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