Shigeo Koyasu
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Shigeo Koyasu's Degrees
- PhD Immunology University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Shigeo Koyasu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cloning of adiponectin receptors that mediate antidiabetic metabolic effects (2003) (3033)
- Innate lymphoid cells — a proposal for uniform nomenclature (2013) (2061)
- A promoter-level mammalian expression atlas (2014) (1664)
- Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells (2009) (1169)
- Innate Lymphoid Cells: 10 Years On (2018) (1139)
- Mechanisms of action of cyclosporine. (2000) (682)
- PI3K and negative regulation of TLR signaling. (2003) (659)
- ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity (2005) (647)
- T cell-specific loss of Pten leads to defects in central and peripheral tolerance. (2001) (614)
- PI3K-mediated negative feedback regulation of IL-12 production in DCs (2002) (609)
- Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. (1999) (510)
- The role of PI3K in immune cells (2003) (497)
- Development, differentiation, and diversity of innate lymphoid cells. (2014) (485)
- IFN-γ production by antigen-presenting cells: mechanisms emerge (2001) (453)
- Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. (1993) (436)
- Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase (1999) (428)
- The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells (2015) (424)
- Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells. (1999) (358)
- Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses (2015) (306)
- Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins. (1986) (306)
- Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. (2009) (289)
- Induction of Pemphigus Phenotype by a Mouse Monoclonal Antibody Against the Amino-Terminal Adhesive Interface of Desmoglein 3 1 (2003) (286)
- Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation. (2014) (271)
- PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. (2012) (270)
- Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells. (1987) (268)
- ERK and p38 MAPK, but not NF-&kgr;B, Are Critically Involved in Reactive Oxygen Species–Mediated Induction of IL-6 by Angiotensin II in Cardiac Fibroblasts (2001) (267)
- Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. (2008) (266)
- Regulatory Role of Dendritic Cells in Postinfarction Healing and Left Ventricular Remodeling (2012) (256)
- Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus. (2000) (253)
- Synergistic Effects of IL-4 and IL-18 on IL-12-Dependent IFN-γ Production by Dendritic Cells1 (2000) (246)
- Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation (2013) (241)
- An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers. (2015) (222)
- T Lymphocyte Activation Signals for Interleukin-2 Production Involve Activation of MKK6-p38 and MKK7-SAPK/JNK Signaling Pathways Sensitive to Cyclosporin A* (1998) (217)
- Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians (2015) (216)
- Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice (2002) (210)
- IFN-gamma production by antigen-presenting cells: mechanisms emerge. (2001) (209)
- Critical role of IL-15–IL-15R for antigen-presenting cell functions in the innate immune response (2001) (201)
- Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells. (2010) (200)
- Inducible Expression of Stat4 in Dendritic Cells and Macrophages and Its Critical Role in Innate and Adaptive Immune Responses1 (2001) (199)
- Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. (2007) (196)
- Autoantibodies to the heat-shock protein hsp90 in systemic lupus erythematosus. (1988) (164)
- PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction (2003) (155)
- The group 2 innate lymphoid cell (ILC2) regulatory network and its underlying mechanisms (2018) (154)
- FANTOM5 CAGE profiles of human and mouse samples (2017) (153)
- Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell. (1987) (152)
- Two distinct action mechanisms of immunophilin–ligand complexes for the blockade of T‐cell activation (2000) (149)
- Interleukin 12–dependent Interferon γ Production by CD8α+Lymphoid Dendritic Cells (1999) (146)
- Innate lymphoid cells in allergic and nonallergic inflammation. (2016) (144)
- Calmodulin-regulated binding of the 90-kDa heat shock protein to actin filaments. (1986) (142)
- IL-15 Regulates CD8+ T Cell Contraction during Primary Infection1 (2006) (131)
- Absence of memory B cells in patients with common variable immunodeficiency. (2002) (129)
- Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis (2007) (129)
- A soluble multimeric recombinant CD2 protein identifies CD48 as a low affinity ligand for human CD2: divergence of CD2 ligands during the evolution of humans and mice (1993) (120)
- Essential requirement of an invariant V alpha 14 T cell antigen receptor expression in the development of natural killer T cells. (1996) (119)
- Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation* (2009) (118)
- Inflammatory Cytokines and Hypoxia Contribute to 18F-FDG Uptake by Cells Involved in Pannus Formation in Rheumatoid Arthritis (2009) (118)
- Critical Role of p38 and GATA3 in Natural Helper Cell Function (2013) (114)
- Insulin-like growth factors, insulin, and epidermal growth factor cause rapid cytoskeletal reorganization in KB cells. Clarification of the roles of type I insulin-like growth factor receptors and insulin receptors. (1986) (114)
- Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome (2011) (113)
- Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN-gamma production by dendritic cells. (2000) (113)
- Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation (2013) (112)
- IFN‐γ and pro‐inflammatory cytokine production by antigen‐presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension (2002) (111)
- Role of interaction of CD2 molecules with lymphocyte function-associated antigen 3 in T-cell recognition of nominal antigen. (1990) (111)
- Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells. (2005) (108)
- Type 2 innate immune responses and the natural helper cell (2011) (106)
- TLR5-Mediated Phosphoinositide 3-Kinase Activation Negatively Regulates Flagellin-Induced Proinflammatory Gene Expression1 (2006) (101)
- Antigen-induced suppression of the proliferative response of T cell clones. (1988) (101)
- Isolation and analysis of group 2 innate lymphoid cells in mice (2015) (96)
- Activation of gp130 Transduces Hypertrophic Signal Through Interaction of Scaffolding/Docking Protein Gab1 With Tyrosine Phosphatase SHP2 in Cardiomyocytes (2003) (92)
- Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. (2003) (92)
- Milk fat globule epidermal growth factor–8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms (2009) (89)
- Interleukin 3‐specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi‐factor‐dependent myeloid cell lines. (1987) (89)
- Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells (2013) (88)
- Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo (2006) (88)
- Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN (2009) (88)
- Phosphatidylinositol 3-Kinase and NF-κB/Rel Are at the Divergence of CD40-Mediated Proliferation and Survival Pathways (2000) (87)
- Peripheral PDGFRα+gp38+ mesenchymal cells support the differentiation of fetal liver–derived ILC2 (2018) (85)
- CD3+CD16+NK1.1+B220+ large granular lymphocytes arise from both alpha- beta TCR+CD4-CD8- and gamma-delta TCR+CD4-CD8- cells (1994) (83)
- Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris (2002) (83)
- Expression of functional IL‐2 receptors on mature splenic dendritic cells (2000) (81)
- Complementary roles for CD2 and LFA‐1 adhesion pathways during T cell activation (1991) (77)
- Role of Innate Lymphocytes in Infection and Inflammation (2012) (75)
- Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains. (1994) (72)
- Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone. (1985) (71)
- Cutting Edge: mTORC1 in Intestinal CD11c+CD11b+ Dendritic Cells Regulates Intestinal Homeostasis by Promoting IL-10 Production (2012) (71)
- Group 2 innate lymphoid cells and asthma. (2015) (70)
- Desmoglein 3-specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice. (2011) (70)
- Temperature-sensitive ZAP70 Mutants Degrading through a Proteasome-independent Pathway (1999) (70)
- Dynamic regulation of Th17 differentiation by oxygen concentrations. (2012) (67)
- Cross‐linking of T‐cell receptors on double‐positive thymocytes induces a cytokine‐mediated stromal activation process linked to cell death. (1996) (67)
- Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus (2014) (66)
- Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway. (1999) (65)
- T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes (1992) (64)
- BCR targets cyclin D2 via Btk and the p85α subunit of PI3-K to induce cell cycle progression in primary mouse B cells (2003) (62)
- Distribution among tissues and intracellular localization of cofilin, a 21kDa actin-binding protein. (1987) (61)
- Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture. (2004) (61)
- Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells. (1990) (59)
- Development of CD4-CD8- alpha beta TCR+NK1.1+ T lymphocytes: thymic selection by self antigen. (1996) (56)
- Natural helper cells: a new player in the innate immune response against helminth infection. (2010) (55)
- Cutting Edge: LFA-1 Is Required for Liver NK1.1+TCRαβ+ Cell Development: Evidence That Liver NK1.1+TCRαβ+ Cells Originate from Multiple Pathways (1999) (54)
- In vivo role of IFN‐γ produced by antigen‐presenting cells in early host defense against intracellular pathogens (2003) (54)
- Establishment of a Real-Time, Quantitative, and Reproducible Mouse Model of Staphylococcus Osteomyelitis Using Bioluminescence Imaging (2011) (50)
- A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice (2004) (50)
- Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo (2011) (50)
- A BACTERIAL EFFECTOR TARGETS MAD 2 L 2 , AN APC INHIBITOR , TO MODULATE HOST CELL (2009) (49)
- Tolerance induction by the blockade of CD40/CD154 interaction in pemphigus vulgaris mouse model. (2006) (49)
- A heat shock-resistant variant of Chinese hamster cell line constitutively expressing heat shock protein of Mr 90,000 at high level. (1986) (49)
- Functional analysis of immunoreceptor tyrosinebased activation motif (ITAM)‐mediated signal transduction: the two YxxL segments within a single CD3ζITAM are functionally distinct (1997) (48)
- Caulobacter crescentus flagellar filament has a right-handed helical form. (1984) (48)
- CD3 eta and CD3 zeta are alternatively spliced products of a common genetic locus and are transcriptionally and/or post-transcriptionally regulated during T-cell development. (1991) (48)
- The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. (2007) (45)
- Regulation of MAPK signaling pathways through immunophilin-ligand complex. (2003) (45)
- Innate Lymphoid Cells in the Induction of Obesity. (2019) (45)
- Cutting Edge: A Possible Role for CD4+ Thymic Macrophages as Professional Scavengers of Apoptotic Thymocytes 1 (2003) (45)
- Negative feedback loop in T‐cell activation through MAPK‐catalyzed threonine phosphorylation of LAT (2004) (44)
- HSP100, a 100-kDa heat shock protein, is a Ca2+-calmodulin-regulated actin-binding protein. (1989) (44)
- Protein kinase C-dependent and -independent pathways in the growth factor-induced cytoskeletal reorganization. (1989) (43)
- Antigen-independent development of Foxp3+ regulatory T cells suppressing autoantibody production in experimental pemphigus vulgaris. (2011) (43)
- A novel hydroxyapatite film coated with ionic silver via inositol hexaphosphate chelation prevents implant-associated infection (2016) (42)
- Development of chimeric molecules for recognition and targeting of antigen‐specific B cells in pemphigus vulgaris (2000) (41)
- Phosphoinositide 3-Kinase in Nitric Oxide Synthesis in Macrophage (2006) (41)
- Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris. (2002) (41)
- Innate Th2-type immune responses and the natural helper cell, a newly identified lymphocyte population (2011) (41)
- The high affinity Fc epsilon receptor gamma subunit (Fc epsilon RI gamma) facilitates T cell receptor expression and antigen/major histocompatibility complex-driven signaling in the absence of CD3 zeta and CD3 eta. (1991) (41)
- Alteration in growth, cell morphology, and cytoskeletal structures of KB cells induced by epidermal growth factor and transforming growth factor-beta. (1988) (40)
- Critical role of NK but not NKT cells in acute rejection of parental bone marrow cells in F1 hybrid mice (2001) (40)
- Regulation of polar morphogenesis in Caulobacter crescentus (1981) (39)
- Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s. (2020) (39)
- Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells (2015) (39)
- Impaired B Cell Development and Function in the Absence of IκBNS (2011) (38)
- The prostaglandin E2 receptor EP4 is integral to a positive feedback loop for prostaglandin E2 production in human macrophages infected with Mycobacterium tuberculosis (2013) (36)
- Delayed Propionibacterium acnes surgical site infections occur only in the presence of an implant (2016) (36)
- Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia (2018) (36)
- The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. (2008) (36)
- PI3K is a negative regulator of IgE production. (2008) (35)
- Phosphorylation of multiple CD3 zeta tyrosine residues leads to formation of pp21 in vitro and in vivo. Structural changes upon T cell receptor stimulation. (1992) (35)
- Pre-TCR signaling components trigger transcriptional activation of a rearranged TCR alpha gene locus and silencing of the pre-TCR alpha locus: implications for intrathymic differentiation. (1997) (34)
- Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression (2012) (33)
- Double‐positive T cell receptorhigh thymocytes are resistant to peptide/major histocompatibility complex ligand‐induced negative selection (1997) (33)
- Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies (2003) (33)
- Targeted disruption within the CD3 zeta/eta/phi/Oct‐1 locus in mouse. (1994) (32)
- Expression of interleukin 2 receptors on interleukin 3-dependent cell lines. (1986) (32)
- Regulation by intracellular Ca2+ and cyclic AMP of the growth factor-induced ruffling membrane formation and stimulation of fluid-phase endocytosis and exocytosis. (1989) (31)
- Are ILC2s Jekyll and Hyde in airway inflammation? (2017) (31)
- Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells. (2013) (31)
- Cutting edge: LFA-1 is required for liver NK1.1+TCR alpha beta+ cell development: evidence that liver NK1.1+TCR alpha beta+ cells originate from multiple pathways. (1999) (30)
- VIP36 Protein Is a Target of Ectodomain Shedding and Regulates Phagocytosis in Macrophage Raw 264.7 Cells* (2011) (29)
- An antibacterial coated polymer prevents biofilm formation and implant-associated infection (2021) (29)
- Purification and characterization of the 90-kDa heat-shock protein from mammalian tissues. (1988) (28)
- Critical role of dendritic cells in determining the Th1/Th2 balance upon Leishmania major infection. (2008) (28)
- The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation. (2016) (28)
- Innate lymphoid cells, possible interaction with microbiota (2014) (28)
- A Mr = 190,000 glycoprotein phosphorylated on tyrosine residues in epidermal growth factor stimulated KB cells is the product of the c-erbB-2 gene. (1987) (28)
- Mouse CD94 Participates in Qa-1-Mediated Self Recognition by NK Cells and Delivers Inhibitory Signals Independent of Ly-494 (2001) (27)
- Rapid stimulation of fluid-phase endocytosis and exocytosis by insulin, insulin-like growth factor-I, and epidermal growth factor in KB cells. (1988) (26)
- Interleukin 12 – dependent Interferon g Production by CD 8 a 1 Lymphoid Dendritic Cells (1999) (26)
- Identification of a cell surface 105 kd protein (Aic-2 antigen) which binds interleukin-3. (1990) (26)
- Signals for activation and proliferation of murine T lymphocyte clones. (1987) (25)
- ERK5 is involved in TCR‐induced apoptosis through the modification of Nur77 (2008) (25)
- Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms. (1991) (25)
- Cancer Immunoediting by Innate Lymphoid Cells. (2019) (24)
- The role of PI 3 K in immune cells (2003) (24)
- Plastic Heterogeneity of Innate Lymphoid Cells in Cancer. (2017) (24)
- Ultrastructural changes in mice actively producing antibodies to desmoglein 3 parallel those in patients with pemphigus vulgaris (2002) (23)
- The p85α Regulatory Subunit of Class IA Phosphoinositide 3-Kinase Regulates β-Selection in Thymocyte Development1 (2007) (23)
- JNK (c-Jun NH2 Terminal Kinase) and p38 during Ischemia Reperfusion Injury in the Small Intestine (2006) (22)
- Critical role of class IA PI3K for c-Rel expression in B lymphocytes. (2009) (21)
- Th2‐type innate immune responses mediated by natural helper cells (2013) (21)
- T cell receptor-independent CD2 signal transduction in FcR+ cells (1991) (21)
- Sequential polymerization of flagellin A and flagellin B into Caulobacter flagella. (1981) (21)
- Hide and seek: Plasticity of innate lymphoid cells in cancer. (2019) (20)
- Impairment of T cell interactions with antigen‐presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF‐κB in immunological synapse formation (2007) (20)
- The penicillin-binding proteins of Caulobacter crescentus. (1980) (20)
- TAK1–JNK Axis Mediates Survival Signal through Mcl1 Stabilization in Activated T Cells (2013) (20)
- IL-2 and IL-7 differentially induce CD4-CD8- alpha beta TCR+NK1.1+ large granular lymphocytes and IL-4-producing cells from CD4-CD8- alpha beta TCR+NK1.1- cells: implications for the regulation of Th1- and Th2-type responses. (1997) (19)
- Inflammatory ILC2 cells: disguising themselves as progenitors? (2015) (19)
- T lymphocyte development in the absence of Fcϵ receptor Iγ subunit: analysis of thymic‐dependent and independent αβ and γδ pathways (1996) (19)
- Overexpression of Bcl-2 Differentially Restores Development of Thymus-Derived CD4−8+ T Cells and Intestinal Intraepithelial T Cells in IFN-Regulatory Factor-1-Deficient Mice1 (2001) (19)
- An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned (2016) (18)
- Energy of adhesion of human T cells to adsorption layers of monoclonal antibodies measured by a film trapping technique. (1998) (17)
- The p85alpha regulatory subunit of class IA phosphoinositide 3-kinase regulates beta-selection in thymocyte development. (2007) (17)
- Differential regulation of T-cell receptor processing and surface expression affected by CD3 theta, an alternatively spliced product of the CD3 zeta/eta gene locus. (1992) (16)
- Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cells1 (2004) (16)
- Differential effects on expression of IL‐2 receptors (p55 and p70) by the HTLV‐I pX DNA (1988) (16)
- ZAP‐70 is required for calcium mobilization but is dispensable for mitogen‐activated protein kinase (MAPK) superfamily activation induced via CD2 in human T cells (2000) (16)
- PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. (2021) (16)
- Pre-TCR signaling components trigger transcriptional activation of a rearranged TCR α gene locus and silencing of the pre-TCR α locus : implications for intrathymic differentiation (1997) (16)
- Autoreactive B-cell elimination by pathogenic IgG specific for the same antigen: implications for peripheral tolerance. (2008) (15)
- Characterization of two flagella‐related protein from Caulobacter crescentus (1978) (15)
- Dendritic cells suppress IgE production in B cells. (2006) (15)
- Critical Roles of NK and CD8+ T Cells in Central Nervous System Listeriosis1 (2009) (15)
- Suppression of the immune response against exogenous desmoglein 3 in desmoglein 3 knockout mice: an implication for gene therapy. (2003) (14)
- Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris. (2011) (13)
- corrigendum: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects (2004) (12)
- Growth regulation of multi-factor-dependent myeloid cell lines: IL-4, TGF-beta and pertussis toxin modulate IL-3- or GM-CSF-induced growth by controlling cell cycle length. (1989) (12)
- How Many Subsets of Innate Lymphoid Cells Do We Need? (2017) (12)
- Characterization of thymus-derived lymphocytes expressing Ti alpha-beta CD3 gamma delta epsilon zeta-zeta, Ti alpha-beta CD3 gamma delta epsilon eta-eta or Ti alpha-beta CD3 gamma delta epsilon zeta-zeta/zeta- eta antigen receptor isoforms: analysis by gene transfection (1990) (12)
- Auto-reactive B cells against peripheral antigen, desmoglein 3, escape from tolerance mechanism. (2004) (11)
- Characterization of an antigen-specific suppressive factor derived from a cloned suppressor effector T cell line. (1984) (11)
- Penicillin-binding proteins of the stalk of Caulobacter crescentus (1983) (11)
- Positive selection of CD4+ T cells by TCR‐specific antibodies requires low valency TCR cross‐linking: implications for repertoire selection in the thymus (1998) (11)
- Response to Comment on “Critical Roles of NK and CD8+ T Cells in Central Nervous System Listeriosis” (2009) (10)
- A fraction of CD3 epsilon subunits exists as disulfide-linked dimers in both human and murine T lymphocytes. (1990) (10)
- A Novel Mouse Model of Soft-Tissue Infection Using Bioluminescence Imaging Allows Noninvasive, Real-Time Monitoring of Bacterial Growth (2014) (10)
- TGF-β-induced phosphorylation of Akt and Foxo transcription factors negatively regulates induced regulatory T cell differentiation. (2016) (10)
- Penicillin-Binding Proteins in the Soluble Fraction of Caulobacter crescentus (1982) (10)
- Autoimmunity against M2 muscarinic acetylcholine receptor induces myocarditis and leads to a dilated cardiomyopathy‐like phenotype (2012) (9)
- Characterization of a B cell-derived growth-enhancing factor produced by a human B cell line established from a patient with rheumatoid arthritis. (1987) (9)
- T-cell receptor isoforms and signal transduction. (1991) (9)
- The expression of IL-2R alpha-chain is enhanced by activation of adenylate cyclase in large granular lymphocytes and natural killer cells. (1991) (9)
- Role of class IA phosphoinositide 3-kinase in B lymphocyte development and functions. (2004) (8)
- The role of phosphoinositide-3-kinase in mast cell homing to the gastrointestinal tract. (2005) (8)
- Role of antigen-presenting cells in innate immune system. (2001) (8)
- mTOR and GSK 3 differentially regulate LPS-induced IL-12 production in dendritic cells (2008) (8)
- Two YxxL segments of a single immunoreceptor tyrosine‐based activation motif in the CD3ζ molecule differentially activate calcium mobilization and mitogen‐activated protein kinase family pathways (2000) (7)
- Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation (2020) (7)
- Properties of the Penicillin-binding Proteins of Caulobacter (1981) (7)
- Mechanisms to Suppress ILC2-induced Airway Inflammation. (2016) (6)
- A proteomic approach for the elucidation of the specificity of ectodomain shedding. (2014) (6)
- Natural "helper" cells in the lung: good or bad help? (2012) (6)
- PI 3 K and Btk differentially regulate B cell antigen receptor-mediated signal transduction (2003) (5)
- The biology of human CD2. (1989) (5)
- Sunday, 26 August 2012 (2012) (5)
- Activation of gp 130 Transduces Hypertrophic Signal Through Interaction of Scaffolding / Docking Protein Gab 1 With Tyrosine Phosphatase SHP 2 in Cardiomyocytes (2003) (5)
- [Role of phosphatidylinositol 3-kinase in the immune system]. (2006) (4)
- T-cell-receptor isoforms. (1992) (4)
- T lymphocyte development in the absence of Fc epsilon receptor I gamma subunit: analysis of thymic-dependent and independent alpha beta and gamma delta pathways. (1996) (4)
- c‐Jun N‐terminal kinase activation during warm hepatic ischemia/reperfusion injuries in a rat model (2002) (4)
- Survival Pathways Are at the Divergence of CD 40-Mediated B / Rel κ Phosphatidylinositol 3-Kinase and NF (2000) (4)
- Workshop 8Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein in multi-factor-dependent myeloid cell lines (1988) (4)
- Characterization of the Mouse Interleukin 3 Receptor System (1989) (4)
- On flagellar formation in Caulobacter crescentus: novel flagellin synthesis in stub-forming non-motile mutants of C. crescentus. (1984) (4)
- Beating a kinase? (2001) (3)
- Introduction: Innate Lymphoid Cells Special Issue. (2016) (3)
- [A second target of cyclosporin A and FK506]. (2000) (3)
- Immunity to protozoan parasite infection (PP-002) (2010) (3)
- Reduced T cell expansion by a superantigen as a result of impaired B cell development in mice deficient for the p85α regulatory subunit of PI3K (2010) (3)
- Innate Lymphoid Cells in Skin Homeostasis and Malignancy (2021) (3)
- 70-75 kd molecules expressed on LGL and T cells recognized by a mitogenic monoclonal antibody YTA-1; co-modulation and functional association with the interleukin 2 receptor p75. (1990) (3)
- Alteration in penicillin-binding patterns during cell cycle of Caulobacter crescentus. (1984) (3)
- Natural Helper Cells and TH2-Type Innate Immunity (2012) (3)
- current as Homeostasis by Promoting IL-10 Production Dendritic Cells Regulates Intestinal + CD 11 b + Cutting Edge : mTORC 1 in Intestinal CD 11 (2012) (3)
- IL-2 enhancing factor(s) in B cell supernatants from patients with rheumatoid arthritis or systemic lupus erythematosus. (1989) (2)
- A 3D Skin Melanoma Spheroid-Based Model to Assess Tumor-Immune Cell Interactions. (2020) (2)
- Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2021) (2)
- IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse. (2022) (2)
- The Pten/PI3K pathway governs the homeostasis of V (cid:1) 14 i NKT cells (2006) (2)
- HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice. (2011) (2)
- Group 2 Innate Lymphoid Cells Exacerbate Amebic Liver Abscess in Mice (2020) (2)
- A fraction of CD3 epsilon subunits exists as disulfide-linked dimers in both human and murine T lymphocytes. (1990) (1)
- Penicillin-Binding Proteins in Soluble Fraction of Escherichia coli K-12 (1980) (1)
- [Identification of natural helper cell]. (2010) (1)
- Cell growth, cytoskeleton, and heat shock proteins. (1991) (1)
- Immunity to bacterial infection (excluding mycobacteria) (PP-060) (2010) (1)
- [Group 2 innate lymphoid cells (ILC2s)]. (2015) (1)
- Helper Cell Function Critical Role of p38 and GATA3 in Natural (2015) (1)
- [Function of MAPK signaling pathways in the immune system]. (2002) (1)
- Nilotinib and MEK Inhibitors Induce Synthetic Lethality through Paradoxical Activation of RAF in Drug-Resistant Chronic Myeloid Leukemia (2011) (1)
- 1876-P: Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans (2020) (1)
- A novel effect of the antigenic peptides position for presentation upon MHC class I (2019) (1)
- Pathogen-induced systemic plant signal triggers DNA rearrangements (2003) (1)
- [Regulatory mechanisms of NK cell functions]. (1999) (1)
- [Functions of heat shock proteins, HSP 70 and HSP 90 in higher eucaryotes]. (1988) (1)
- Vanilloid flavor for a good appetite? (2010) (1)
- Dendritic cells: function (PP-024) (2010) (0)
- TSLP Induces Corticosteroid Resistance In Natural Helper Cells Via STAT5 Pathway (2014) (0)
- Cancer immunosurveillance by ILC2s. (2022) (0)
- Class IA PI3K is involved in the pre-B cell antigen receptor-mediated signaling (86.6) (2007) (0)
- FcgRIIb is critical to establish clonal ignorance and suppress pemphigus phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice (2017) (0)
- Innate lymphoid cells, possible interaction with microbiota (2014) (0)
- sample information of the human samples (2017) (0)
- IDENTITICATION OF COFILIN IN TISSUES AND LOCALIZATION IN CULTURED CELLS : Biochemistry (1986) (0)
- Detection of pemphigus vulgaris antigen (desmoglein 3) -specific B cells by enzyme-linked immunospot (ELISPOT) assay (1998) (0)
- DEVELOPMENT OF NEW TECHNIQUES FOR IDENTIFICATION, PURIFICATION AND CHARACTERIZATION OF CANCER CELL-SPECIFIC PROTEINS (1989) (0)
- Desmoglein 3 Amino-Terminal Adhesive Interface of Mouse Monoclonal Antibody Against the Induction of Pemphigus Phenotype by a (2003) (0)
- 007 Essential requirement for IRF7 in autoantibody production but not development of glomerulonephritis in murine lupus (2017) (0)
- 008 VGLL3 is a key regulator of transcriptome changes in gender biased autoimmune conditions (2017) (0)
- Functional characterization of mouse CD94 by using a novel monoclonal antibody (2001) (0)
- characterized by an impaired response to GP VI stimulation null platelets α Functional phenotype of phosphoinositide 3-kinase p85 (2003) (0)
- Penicillin . Binding Proteins in Soluble Fraction o f Escherichia coli K . 12 (2006) (0)
- P12 Clarithromycin expands CD11b+Gr–1+ cells to protect against LPS-induced lethal shock and polymicrobial sepsis (2013) (0)
- [Recognition of class I MHC by inhibitory receptors on natural killer cells]. (1998) (0)
- Translational Immunology in Asia-Oceania Th 2-type innate immune responses mediated by natural helper cells (2013) (0)
- recognition and its disorders (2009) (0)
- during Primary Infection T Cell Contraction + IL-15 Regulates CD8 (0)
- Liver NK 1 . 1 Cell Development : Evidence + βα TCR + NK 1 . 1 Cutting Edge : LFA-1 Is Required for Liver Mak and (1999) (0)
- Correction: Critical Role of p38 and GATA3 in Natural Helper Cell Function (2014) (0)
- 013 Fcγ receptor IIb-dependent blockade of immunoglobulin class-switch is crucial to prevent pemphigus onset in desmoglein 3-sepecific B cell receptor knock-in mouse (2020) (0)
- Electron microscopy of Caulobacter straight flagellar polymers. (1983) (0)
- Rheumatoid arthritis and other inflammatory joint diseases (animal models) (PP-037) (2010) (0)
- Role of Phosphoinositide 3‐kinase in induction and maintenance of B cell self tolerance (2008) (0)
- [The cytokine cascade: feature of cytokine action]. (1987) (0)
- genomic coordinates of the mouse CAGE peaks (2017) (0)
- Immunity to virus infection (excluding retroviruses) (PP-025) (2010) (0)
- Role of class IA PI3K in regulatory T cell function (179.5) (2012) (0)
- Corrigendum to ‘Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus’ [Virology (2014) 157–168] (2016) (0)
- Anti-desmoglein 3 IgG production is reduced by intravenous immunoglobulin in B220− antibody-secreting cells in mice with pemphigus vulgaris (2016) (0)
- in Innate and Adaptive Immune Responses Cells and Macrophages and Its Critical Role Inducible Expression of Stat4 in Dendritic (2013) (0)
- [Clinical significance of interleukin-3 analysis]. (1990) (0)
- Differential signal transduction via T-cell receptor CD 3 ' 2 , CD 3 C-, v , and CD 3 ' q 2 isoforms ( Ca 2 + mobilization / phosphatidylinositol turnover / protein tyrosine kinase / interleukin 2 production ) (0)
- Characterization of Thymus-derived Lymphocytes Expressing Tia-fCD 3 y 8 Er ~ , Tia-0 CD 3 ybf 7 ?-n or Tia-aCD 3 , yber ~ / rq Antigen Receptor Isoforms : Analysis by Gene Transfection By (2003) (0)
- Dendritic Cells Production by γ IL-12-Dependent IFN-Synergistic Effects of IL-4 and IL-18 on (1999) (0)
- Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
- Homeostasis by Promoting IL-10 Production Dendritic Cells Regulates Intestinal + CD11b + Cutting Edge: mTORC1 in Intestinal CD11c (2012) (0)
- T Cell Receptor Complexes Containing FcERI 3 , Homodimers in Lieu of CD 3 ~ " and CD 3 v / Components : A Novel Isoform Expressed on Large Granular Lymphocytes (2003) (0)
- On the 50 th Anniversary of the Japanese Society for Immunology (2021) (0)
- 010 FcgRIIb is important for clonal ignorance and prevents pemphigus phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice (2017) (0)
- VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage raw 264.7 cells. (2014) (0)
- Regulatory role of phosphoinositide 3-kinase in immune response (2005) (0)
- genomic coordinates of the human CAGE peaks (2017) (0)
- 017 FcγRIIb deficiency accelerates immunoglobulin class switch and pemphigus phenotype development in pathogenic anti-desmoglein 3 antibody knock-in mice (2018) (0)
- Th17 (WS-014) Chairpersons: Akihiko Yoshimura, Joseph E. Craft (2010) (0)
- expression table of the human CAGE peaks (2017) (0)
- Immunity to bacterial infection (excluding mycobacteria) (WS-060) Chairpersons: Masao Mitsuyama, Seppo Meri (2010) (0)
- 015 Interleukin-27 alleviates psoriatic inflammation by suppressing Interleukin-17A production from T17 cells (2020) (0)
- P71W5-5 Dendritic cells determine Th1/Th2 response in experimental leishmaniasis (2001) (0)
- Abstract 2936:In situantitumor immunotherapy with pharmacological blockade of MFG-E8 and chemotherapy against solid and hematological tumors (2010) (0)
- Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris (1998) (0)
- Studies on the Antibiotic Substances in the Soil. I. Isolation, Distribution, Classification and Antibiotic Action of the Antibiotic Microbes. (1949) (0)
- [Signals for T cell growth]. (1986) (0)
- VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage Raw 264.7 cells. (2012) (0)
- Expression Flagellin-Induced Proinflammatory Gene Activation Negatively Regulates TLR 5-Mediated Phosphoinositide 3-Kinase (2006) (0)
- Pillars Article: Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes. Science. 1993. 259: 822-825. (2019) (0)
- TLR5‐mediated PI3K activation negatively regulates flagellin‐induced pro‐inflammatory gene expression (2006) (0)
- Abstract 12240: Dendritic Cell is an Immunoprotective Regulator in Post-Infarction Healing and Left Ventricular Remodeling (2011) (0)
- Intrathymic T Cell Progenitors Is Induced by Macrophages from + Development of CD 4 Shigeo Koyasu and Atsushi Miyajima (2004) (0)
- [Natural killer T cells: their origin and functions]. (1997) (0)
- Inhibitory Signals Independent of Ly-49 Self Recognition by NK Cells and Delivers Mouse CD94 Participates in Qa-1-Mediated (2013) (0)
- Inflammatory cytokines and anti-microbial responses (WS-068) Chairpersons: Yasunobu Yoshikai, Xiaoxia Li (2010) (0)
- Inhibition of immunoglobulin class-switching prevents pemphigus onset in desmoglein 3-specific B cell receptor knock-in mouse (2021) (0)
- Advances in Immunology (2010) (0)
- Scaffolding / Docking Protein Gab 1 With Tyrosine Phosphatase SHP 2 in Cardiomyocytes Activation of gp 130 Transduces Hypertrophic Signal Through Interaction of (2003) (0)
- 2-B2-205 Developmental and functional impairment of B lymphocytes in mice lacking the p85a regulatory subunit of phosphatidylinositol-3 kinase (2008) (0)
- Right-handed flagella in tumbling Caulobacter (1985) (0)
- BNS k in the Absence of I Impaired B Cell Development and Function (2011) (0)
- assay information of the mouse qualitycontrol samples for HeliScopeCAGE (2017) (0)
- ILC2s and Adipose Tissue Homeostasis: Progress to Date and the Road Ahead (2022) (0)
- Interactions Between CD2 and T-Cell Receptor Isoforms in CTL Function (1993) (0)
- Innate immunity 2 (innate cells) (SY1-2) Chairpersons: Shigeo Koyasu, Caetano Reis e Sousa (2010) (0)
- [Cytokines and receptors--their functions, structures and cloning of code genes. Interleukin-3]. (1988) (0)
- Selection in Thymocyte Development β Phosphoinositide 3-Kinase Regulates Regulatory Subunit of Class IA α The p 85 Suzuki and (2007) (0)
- Th17 (PP-014) (2010) (0)
- Signal-Regulated Kinase Pathway That Is Suppressed by the Extracellular LymphocytesFTY 720-Induced Apoptosis of T-Terminal Kinase and p 38 Pathways During 2 Differential Activation of c-Jun NH (1999) (0)
- SPECIFIC ROLES OF PHOSPHOINOSITIDE 3-KINASE ISOFORMS ALPHA AND BETA IN GLYCOPROTEIN VI-INDUCED PLATELET SIGNALING TO PROCOAGULANT ACTIVITY (2007) (0)
- Flagellin-Induced Proinflammatory Gene Activation Negatively Regulates TLR5-Mediated Phosphoinositide 3-Kinase (2006) (0)
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What Schools Are Affiliated With Shigeo Koyasu?
Shigeo Koyasu is affiliated with the following schools: