Shiladitya DasSarma
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Indian-American molecular biologist
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Shiladitya DasSarmabiology Degrees
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#2486
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#3934
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#1108
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Microbiology
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#1068
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#171
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Molecular Biology
#2468
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#2507
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#263
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Biology
Shiladitya DasSarma's Degrees
- PhD Microbiology University of California, Berkeley
- Masters Microbiology University of Calcutta
- Bachelors Microbiology University of Calcutta
Why Is Shiladitya DasSarma Influential?
(Suggest an Edit or Addition)According to Wikipedia, Shiladitya DasSarma is a molecular biologist well-known for contributions to the biology of halophilic and extremophilic microorganisms. He is a Professor in the University of Maryland Baltimore. He earned a PhD degree in biochemistry from the Massachusetts Institute of Technology and a BS degree in chemistry from Indiana University Bloomington. Prior to taking a faculty position, he conducted research at the Massachusetts General Hospital, Harvard Medical School, and Pasteur Institute, Paris.
Shiladitya DasSarma's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome sequence of Halobacterium species NRC-1. (2000) (706)
- Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequence. (2001) (322)
- Exoplanet Biosignatures: A Review of Remotely Detectable Signs of Life (2017) (272)
- Function and biotechnology of extremophilic enzymes in low water activity (2012) (198)
- Halophiles and their enzymes: negativity put to good use. (2015) (191)
- Homologous gene knockout in the archaeon Halobacterium salinarum with ura3 as a counterselectable marker (2000) (188)
- Exoplanet Biosignatures: Understanding Oxygen as a Biosignature in the Context of Its Environment (2017) (164)
- Arsenic Resistance in Halobacterium sp. Strain NRC-1 Examined by Using an Improved Gene Knockout System (2004) (146)
- Saline Systems: A research journal bridging gene systems and ecosystems (2005) (123)
- Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid or minichromosome? (1998) (119)
- Exoplanet Biosignatures: A Framework for Their Assessment (2017) (113)
- Detection of circular polarization in light scattered from photosynthetic microbes (2009) (112)
- Is gene expression in Halobacterium NRC‐1 regulated by multiple TBP and TFB transcription factors? (2000) (110)
- Genomic Analysis of Anaerobic Respiration in the Archaeon Halobacterium sp. Strain NRC-1: Dimethyl Sulfoxide and Trimethylamine N-Oxide as Terminal Electron Acceptors (2005) (106)
- UV irradiation induces homologous recombination genes in the model archaeon, Halobacterium sp. NRC-1 (2005) (96)
- An Archaeal Chromosomal Autonomously Replicating Sequence Element from an Extreme Halophile, Halobacterium sp. Strain NRC-1 (2003) (95)
- brp and blh Are Required for Synthesis of the Retinal Cofactor of Bacteriorhodopsin in Halobacterium salinarum * (2001) (90)
- The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1 (2006) (90)
- Transcriptional profiling of the model Archaeon Halobacterium sp. NRC-1: responses to changes in salinity and temperature (2007) (88)
- Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains. (1984) (88)
- High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. (1983) (88)
- Extremely Radiation-Resistant Mutants of a Halophilic Archaeon with Increased Single-Stranded DNA-Binding Protein (RPA) Gene Expression (2007) (87)
- Wild-type gas vesicle formation requires at least ten genes in the gvp gene cluster of Halobacterium halobium plasmid pNRC100 (1994) (85)
- Circular polarization in scattered light as a possible biomarker (2009) (85)
- Extreme Halophiles Are Models for Astrobiology (2006) (83)
- Exoplanet Biosignatures: Future Directions (2017) (82)
- A plasmid‐encoded gas vesicle protein gene in a halophilic archaebacterium (1987) (79)
- Cloning, overexpression, purification, and characterization of a polyextremophilic β-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi (2013) (79)
- The rightward gas vesicle operon in Halobacterium plasmid pNRC100: identification of the gvpA and gvpC gene products by use of antibody probes and genetic analysis of the region downstream of gvpC (1993) (74)
- Genomic and genetic dissection of an archaeal regulon (2001) (74)
- Essential and non-essential DNA replication genes in the model halophilic Archaeon, Halobacterium sp. NRC-1 (2007) (73)
- Terrestrial models for extraterrestrial life: methanogens and halophiles at Martian temperatures (2006) (69)
- Complexity of Gas Vesicle Biogenesis in Halobacterium sp. Strain NRC-1: Identification of Five New Proteins (2004) (66)
- Structure and Function of Cold Shock Proteins in Archaea (2007) (65)
- Structure and organization of the gas vesicle gene cluster on the Halobacterium halobium plasmid pNRC100. (1991) (64)
- Genetic and transcriptomic analysis of transcription factor genes in the model halophilic Archaeon: coordinate action of TbpD and TfbA (2007) (63)
- Amino Acid Substitutions in Cold-Adapted Proteins from Halorubrum lacusprofundi, an Extremely Halophilic Microbe from Antarctica (2013) (58)
- Genomic perspective on the photobiology of Halobacterium species NRC-1, a phototrophic, phototactic, and UV-tolerant haloarchaeon (2004) (57)
- Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1 (2006) (57)
- Genetic analysis of the gas vesicle gene cluster in haloarchaea (1997) (57)
- Minimal replication origin of the 200-kilobase Halobacterium plasmid pNRC100 (1993) (57)
- Mechanisms of genetic variability in Halobacterium halobium: the purple membrane and gas vesicle mutations. (1989) (54)
- Plant glutamine synthetase complements a glnA mutation in Escherichia coli. (1986) (53)
- Survival of microbes in Earth's stratosphere. (2018) (51)
- Low-pass sequencing for microbial comparative genomics (2004) (50)
- Transcriptional induction of purple membrane and gas vesicle synthesis in the archaebacterium Halobacterium halobium is blocked by a DNA gyrase inhibitor (1990) (49)
- Analysis of insertion mutants reveals two new genes in the pNRC100 gas vesicle gene cluster of Halobacterium halobium. (1989) (48)
- Microbial Diversity of Great Salt Lake (2005) (48)
- Halophiles, Industrial Applications (2010) (47)
- Antigen presentation using novel particulate organelles from halophilic archaea. (2001) (47)
- Saline Systems highlights for 2005 (2006) (47)
- The information transfer system of halophilic archaea. (2011) (46)
- Structure of the gas vesicle plasmid in Halobacterium halobium: inversion isomers, inverted repeats, and insertion sequences (1991) (46)
- High-frequency mutations in a plasmid-encoded gas vesicle gene in Halobacterium halobium. (1988) (45)
- The core and unique proteins of haloarchaea (2012) (44)
- Saline Systems highlights for 2006 (2007) (43)
- Genetic and topological analyses of the bop promoter of Halobacterium halobium: stimulation by DNA supercoiling and non-B-DNA structure (1996) (43)
- Transcriptional responses to biologically relevant doses of UV-B radiation in the model archaeon, Halobacterium sp. NRC-1 (2008) (43)
- Saturation Mutagenesis of the TATA Box and Upstream Activator Sequence in the Haloarchaeal bop Gene Promoter (1999) (41)
- A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. (1982) (41)
- Aquatic biosystems: reactions and actions (2012) (39)
- Cassette-based presentation of SIV epitopes with recombinant gas vesicles from halophilic archaea. (2004) (39)
- Nucleotide sequence of an alfalfa glutamine synthetase gene (1986) (39)
- HaloWeb: the haloarchaeal genomes database (2010) (39)
- Gas Vesicle Nanoparticles for Antigen Display (2015) (39)
- An Antarctic Extreme Halophile and Its Polyextremophilic Enzyme: Effects of Perchlorate Salts (2017) (35)
- Genome Sequence of an Extremely Halophilic Archaeon Shiladitya DasSarma (2004) (35)
- 27 Genetic Systems for Halophilic Archaea (2006) (34)
- Extremophilic models for astrobiology: haloarchaeal survival strategies and pigments for remote sensing (2019) (34)
- Multiple Replication Origins of Halobacterium sp. Strain NRC-1: Properties of the Conserved orc7-Dependent oriC1 (2009) (32)
- Dissection of the regulatory mechanism of a heat-shock responsive promoter in Haloarchaea: a new paradigm for general transcription factor directed archaeal gene regulation (2008) (31)
- Saturation mutagenesis of the haloarchaeal bop gene promoter: identification of DNA supercoiling sensitivity sites and absence of TFB recognition element and UAS enhancer activity (2000) (30)
- An improved genetic system for bioengineering buoyant gas vesicle nanoparticles from Haloarchaea (2013) (30)
- Genome-Wide Responses of the Model Archaeon Halobacterium sp. Strain NRC-1 to Oxygen Limitation (2012) (29)
- Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase (2017) (29)
- A Transposable Element from Halobacterium Halobium which Inactivates the Bacteriorhodopsin Gene (1982) (28)
- Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria. (2014) (27)
- Early evolution of purple retinal pigments on Earth and implications for exoplanet biosignatures (2018) (27)
- On the origin of prokaryotic "species": the taxonomy of halophilic Archaea (2008) (27)
- Characterization of the small endogenous plasmid of Halobacterium strain SB3 and its use in transformation of H. halobium. (1989) (25)
- Genetic transformation of a halophilic archaebacterium with a gas vesicle gene cluster restores its ability to float. (1992) (24)
- Immunogenicity and protective potential of a Plasmodium spp. enolase peptide displayed on archaeal gas vesicle nanoparticles (2015) (23)
- Large Deletions in Class III Gas Vesicle-Deficient Mutants of Halobacterium halobium (1993) (22)
- Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34 (2016) (22)
- Earth's Stratosphere and Microbial Life. (2020) (21)
- Bioengineering radioresistance by overproduction of RPA, a mammalian-type single-stranded DNA-binding protein, in a halophilic archaeon (2014) (21)
- Bacterial and Archaeal Inclusions (2011) (21)
- Metagenomic Insights Into the Diversity of Halophilic Microorganisms Indigenous to the Karak Salt Mine, Pakistan (2020) (20)
- Microneedle-Assisted Skin Permeation by Nontoxic Bioengineerable Gas Vesicle Nanoparticles. (2017) (19)
- Recombination between bacteriophage lambda and plasmid pBR322 in Escherichia coli (1980) (18)
- Nucleotide sequence of a high copy number plasmid from Halobacterium strain GRB. (1990) (18)
- Ureases of Extreme Halophiles of the Genus Haloarcula with a Unique Structure of Gene Cluster (2004) (18)
- Analysis of left-handed Z-DNA formation in short d(CG)n sequences in Escherichia coli and Halobacterium halobium plasmids. Stabilization by increasing repeat length and DNA supercoiling but not salinity. (1996) (17)
- Genome sequences of Halobacterium species. (2008) (16)
- Halobacterial nano vesicles displaying murine bactericidal permeability-increasing protein rescue mice from lethal endotoxic shock (2016) (16)
- Effects of road salt on microbial communities: Halophiles as biomarkers of road salt pollution (2019) (15)
- Aquatic Biosystems reviewer acknowledgement 2013 (2014) (14)
- Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase (2020) (13)
- Comparative Genomic Survey of Information Transfer Systems in two Diverse Extremely Halophilic Archaea, Halobacterium Sp. Strain NRC-1 and Haloarcula Marismortui (2005) (13)
- Recent Desiccation-Related Ecosystem Changes at Lake Abert, Oregon: A Terminal Alkaline Salt Lake (2016) (13)
- Inquiry-driven Teaching & Learning Using the Archaeal Microorganism Halobacterium NRC-1 (2016) (11)
- Restriction Mapping the Genome of Halobacterium halobium Strain NRC-1 (1993) (11)
- Halobacterium Expression System for Production of Full-Length Plasmodium falciparum Circumsporozoite Protein (2016) (10)
- Comparative Genomics of Halobacterium Strains From Diverse Locations (2019) (10)
- Isolation and Chromosomal Distribution of Natural Z-DNA-forming Sequences in Halobacterium halobium* (1996) (10)
- Identification and analysis of the gas vesicle gene cluster on an unstable plasmid of Halobacterium halobium. (1993) (10)
- Microbial Growth with Multiple Stressors (2010) (9)
- Genome Sequence and Methylation Patterns of Halorubrum sp. Strain BOL3-1, the First Haloarchaeon Isolated and Cultured from Salar de Uyuni, Bolivia (2019) (8)
- Aminoacylation of an unusual tRNACys from an extreme halophile (2003) (8)
- Identification and analysis of the gas vesicle gene cluster on an unstable plasmid ofHalobacterium halobium (1993) (8)
- Complex Effects of Cytochrome P450 Monooxygenase on Purple Membrane and Bacterioruberin Production in an Extremely Halophilic Archaeon: Genetic, Phenotypic, and Transcriptomic Analyses (2018) (8)
- Physical and Genetic Mapping of the Unstable Gas Vesicle Plasmid in Halobacterium Halobium NRC-1 (1991) (8)
- Genome Sequences and Methylation Patterns of Natrinema versiforme BOL5-4 and Natrinema pallidum BOL6-1, Two Extremely Halophilic Archaea from a Bolivian Salt Mine (2019) (7)
- Genome Sequence of Salarchaeum sp. Strain JOR-1, an Extremely Halophilic Archaeon from the Dead Sea (2020) (7)
- Lake Basin Management Initiative Thematic Paper Conservation and Management Challenges of Saline Lakes : A Review of Five Experience Briefs (2004) (7)
- Structure of the Gas Vesicle Plasmid in Halobacterium halobium: Inversion Isomers, Inverted Repeats, and Insertion Sequences (1991) (6)
- Earth's Stratosphere and Microbial Life (2020) (6)
- 16S rRNA Gene Diversity in the Salt Crust of Salar de Uyuni, Bolivia, the World’s Largest Salt Flat (2020) (6)
- Methylomes of Two Extremely Halophilic Archaea Species, Haloarcula marismortui and Haloferax mediterranei (2019) (5)
- Gas Vesicle Nanoparticles (2021) (5)
- Life Beyond the Solar System: Remotely Detectable Biosignatures (2018) (4)
- Astrobiological signatures: prospects for the detection of non-terrestrial biological material (2007) (4)
- ASTRO-BIOLOGICAL SIGNATURES (2007) (4)
- Aminoacylation of an unusual tRNA(Cys) from an extreme halophile. (2003) (4)
- Faculty Opinions recommendation of Environmental genome shotgun sequencing of the Sargasso Sea. (2004) (3)
- 16S rRNA Gene Diversity in Ancient Gray and Pink Salt from San Simón Salt Mines in Tarija, Bolivia (2020) (3)
- Genome Sequence and Methylation Pattern of Haloterrigena salifodinae BOL5-1, an Extremely Halophilic Archaeon from a Bolivian Salt Mine (2021) (3)
- Correction for Sparks et al., Detection of circular polarization in light scattered from photosynthetic microbes (2009) (3)
- Analysis of Left-handed Z-DNA Formation in Short d(CG) Sequences in Escherichia coli and Halobacterium halobium Plasmids (1996) (3)
- Evolutionary Competition Between Primitive Photosynthetic Systems: Existence of an early purple Earth? (2006) (3)
- Acid Experimental Evolution of the Haloarchaeon Halobacterium sp. NRC-1 Selects Mutations Affecting Arginine Transport and Catabolism (2020) (3)
- Complete Genome Sequence and Methylome Analysis of Micrococcus luteus SA211, a Halophilic, Lithium-Tolerant Actinobacterium from Argentina (2019) (3)
- Faculty Opinions recommendation of Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis. (2004) (3)
- Bioengineering novel floating nanoparticles for protein and drug delivery. (2016) (2)
- We Should Search for Extant Life on Mars in this Decade (2021) (2)
- Complete Genome Sequence of an Extremely Halophilic Archaeon from Great Salt Lake, Halobacterium sp. GSL-19 (2021) (2)
- Genome Sequence of Halobacterium sp. Strain BOL4-2, Isolated and Cultured from Salar de Uyuni, Bolivia (2021) (2)
- Complete Genome and Methylome Analysis of the Box-Shaped Halophilic Archaeon Haloarcula sinaiiensis ATCC 33800 (2021) (2)
- Bioengineering of Halobacterium sp. NRC-1 gas vesicle nanoparticles with GvpC fusion protein produced in E. coli (2022) (2)
- Meridional tris(pyridine)tris(thiocyanato-N)chromium(II) and its conversion to cyanato-N analog by a novel method (1979) (2)
- Acid and Iron Experimental Evolution of Halobacterium sp. NRC-1 (2019) (1)
- The core and unique proteins of haloarchaea (2012) (1)
- Structure oftheGasVesicle Plasmid inHalobacterium halobium: Inversion Isomers, Inverted Repeats, andInsertion Sequences (1991) (1)
- Resistance of the Extreme Halophile Halobacterium sp. NRC‐1 to Multiple Stresses (2009) (1)
- Double mutations far from the active site affect cold activity in an Antarctic halophilic β‐galactosidase (2021) (1)
- Extreme Halophiles Are Models for Astrobiology Tolerance of extremes in salinity, radiation, and temperature may permit halophiles to survive elsewhere in the universe (2006) (1)
- Genetics of Archaea (2007) (1)
- Correction to: Bioengineering of Halobacterium sp. NRC‑1 gas vesicle nanoparticles with GvpC fusion protein produced in E. coli (2022) (1)
- Faculty Opinions recommendation of DNA is preserved and maintains transforming potential after contact with brines of the deep anoxic hypersaline lakes of the Eastern Mediterranean Sea. (2008) (0)
- Towards a Remote Sensing Capability for Life s Chiral Signature using Circular Polarization | NIST (2009) (0)
- Faculty Opinions recommendation of An expanding family of archaeal transcriptional activators. (2005) (0)
- Faculty Opinions recommendation of Divergence and redundancy of 16S rRNA sequences in genomes with multiple rrn operons. (2004) (0)
- Ancient Polyextremophilic Microbes with the Potential for Survival on Mars (2019) (0)
- Faculty Opinions recommendation of Coordinate regulation of energy transduction modules in Halobacterium sp. analyzed by a global systems approach. (2003) (0)
- Faculty Opinions recommendation of Amino acid contacts in proteins adapted to different temperatures: hydrophobic interactions and surface charges play a key role. (2009) (0)
- Faculty Opinions recommendation of The genome of M. acetivorans reveals extensive metabolic and physiological diversity. (2002) (0)
- Exoplanet Biosignatures : A Framework for Their Assessment 1 2 (2017) (0)
- Acid Experimental Evolution of the Extremely Halophilic Archaeon Halobacterium sp. NRC-1 Selects Mutations Affecting Arginine Transport and Catabolism (2019) (0)
- Faculty Opinions recommendation of SHOT: a web server for the construction of genome phylogenies. (2002) (0)
- Role of horizontal gene transfers and microbial ecology in the evolution of fluxes through the tricarboxylic acid cycle (2022) (0)
- Faculty Opinions recommendation of Endospores of halophilic bacteria of the family Bacillaceae isolated from non-saline Japanese soil may be transported by Kosa event (Asian dust storm). (2005) (0)
- Faculty Opinions recommendation of Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon Sulfolobus solfataricus by use of gene disruption. (2004) (0)
- Genomic Analysis of Haloarchaea from Diverse Environments, including Permian Halite, Reveals Diversity of Ultraviolet Radiation Survival and DNA Photolyase Gene Variants (2023) (0)
- Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34 (2016) (0)
- Recombination BetweenBacteriophage LambdaandPlasmid pBR322inEscherichia coli (1980) (0)
- Genome Sequence of the Early 20th-Century Extreme Halophile Halobacterium sp. Strain NRC-34001 (2022) (0)
- Bioengineering radioresistance by overproduction of RPA, a mammalian-type single-stranded DNA-binding protein, in a halophilic archaeon (2013) (0)
- Detection of Circular Polarization in Light Scattered from Microbes (2009) (0)
- Faculty Opinions recommendation of Reassembly of shattered chromosomes in Deinococcus radiodurans. (2006) (0)
- Extremophilic models for astrobiology: haloarchaeal survival strategies and pigments for remote sensing (2019) (0)
- List of Contributors (2019) (0)
- Faculty Opinions recommendation of Archaea and their potential role in human disease. (2003) (0)
- Faculty Opinions recommendation of The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication. (2005) (0)
- Faculty Opinions recommendation of RNAP subunits F/E (RPB4/7) are stably associated with archaeal RNA polymerase: using fluorescence anisotropy to monitor RNAP assembly in vitro. (2009) (0)
- Faculty Opinions recommendation of A single-base resolution map of an archaeal transcriptome. (2010) (0)
- Faculty Opinions recommendation of Repair of UV damage in Halobacterium salinarum. (2003) (0)
- Effects of Salinity and Temperature on the Flexibility and Function of a Polyextremophilic Enzyme (2022) (0)
- Immunogenicity and protective potential of a Plasmodium spp. enolase peptide displayed on archaeal gas vesicle nanoparticles (2015) (0)
- BIOPHYSICS AND COMPUTATIONAL BIOLOGY, ASTRONOMY (2009) (0)
- SURVIVAL OF HALOPHILIC ARCHAEA IN THE STRATOSPHERE AS A MARS ANALOG: A TRANSCRIPTOMIC APPROACH (2016) (0)
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