Shin‐ichi Kohsaka
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Biology
Shin‐ichi Kohsaka's Degrees
- PhD Neuroscience University of Tokyo
- Doctorate Medicine University of Tokyo
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(Suggest an Edit or Addition)Shin‐ichi Kohsaka's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury (2003) (1410)
- Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals (2009) (1378)
- Microglia-specific localisation of a novel calcium binding protein, Iba1. (1998) (1251)
- A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. (1996) (804)
- UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis (2007) (701)
- Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors (2001) (562)
- The origin and cell lineage of microglia—New concepts (2007) (425)
- Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance (2008) (418)
- Extracellular ATP Triggers Tumor Necrosis Factor‐α Release from Rat Microglia (2000) (406)
- Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7 Receptor-Activated Microglia (2004) (392)
- Microglia–Müller Glia Cell Interactions Control Neurotrophic Factor Production during Light-Induced Retinal Degeneration (2002) (368)
- Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia. (2000) (352)
- Intracellular signaling in M‐CSF‐induced microglia activation: Role of Iba1 (2002) (348)
- Microglia: activation and their significance in the central nervous system. (2001) (331)
- Immunohistochemical studies on the proliferation of reactive astrocytes and the expression of cytoskeletal proteins following brain injury in rats. (1988) (285)
- Microglia/macrophage‐specific protein Iba1 binds to fimbrin and enhances its actin‐bundling activity (2004) (283)
- Involvement of P2X4 and P2Y12 receptors in ATP‐induced microglial chemotaxis (2007) (281)
- Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1 (2017) (265)
- Iba1 is an actin-cross-linking protein in macrophages/microglia. (2001) (254)
- Microglia: neuroprotective and neurotrophic cells in the central nervous system. (2004) (253)
- P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury (2008) (251)
- Neurotrophin secretion from cultured microglia (2001) (249)
- Homeostatic and injury-induced microglia behavior in the aging brain (2013) (235)
- Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging (2017) (235)
- Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. (2000) (231)
- Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role (2006) (220)
- Modification of Glial–Neuronal Cell Interactions Prevents Photoreceptor Apoptosis during Light-Induced Retinal Degeneration (2000) (214)
- Functional roles of microglia in the brain (1993) (210)
- Selective expression of Gi/o‐coupled ATP receptor P2Y12 in microglia in rat brain (2003) (209)
- Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro (1996) (188)
- Mechanisms underlying extracellular ATP‐evoked interleukin‐6 release in mouse microglial cell line, MG‐5 (2001) (180)
- Lipopolysaccharide enhances synthesis of brain‐derived neurotrophic factor in cultured rat microglia (1997) (172)
- The microglia/macrophage response in the neonatal rat facial nucleus following axotomy (1998) (165)
- Visualization of microglia in living tissues using Iba1‐EGFP transgenic mice (2005) (162)
- Macrophage/Microglia-specific Protein Iba1 Enhances Membrane Ruffling and Rac Activation via Phospholipase C-γ-dependent Pathway* (2002) (160)
- Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors (2013) (155)
- Amino‐terminal region of secreted form of amyloid precursor protein stimulates proliferation of neural stem cells (1999) (152)
- Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain (1993) (150)
- Identification of Elastase as a Secretory Protease from Cultured Rat Microglia (1992) (140)
- Production of basic fibroblast growth factor in cultured rat brain microglia (1991) (131)
- Microglia isolated from rat brain secrete a urokinase-type plasminogen activator (1992) (130)
- Microglia and the early phase of immune surveillance in the axotomized facial motor nucleus: Impaired microglial activation and lymphocyte recruitment but no effect on neuronal survival or axonal regeneration in macrophage‐colony stimulating factor‐deficient mice (2001) (130)
- P2Y12 receptor‐mediated integrin‐β1 activation regulates microglial process extension induced by ATP (2010) (126)
- Neurotrophins regulate the function of cultured microglia (1998) (122)
- The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S (2013) (119)
- ATP stimulation of Ca2+‐dependent plasminogen release from cultured microglia (1998) (116)
- A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions (1994) (116)
- Predominant Expression of Platelet-Activating Factor Receptor in the Rat Brain Microglia (1996) (115)
- Core Protein of Chondroitin Sulfate Proteoglycan Promotes Neurite Outgrowth from Cultured Neocortical Neurons (1991) (111)
- Plasminogen Binds Specifically to α‐Enolase on Rat Neuronal Plasma Membrane (1994) (110)
- Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy. (2000) (110)
- Long-term changes of spine dynamics and microglia after transient peripheral immune response triggered by LPS in vivo (2011) (108)
- Long-Term In Vivo Imaging of β-Amyloid Plaque Appearance and Growth in a Mouse Model of Cerebral β-Amyloidosis (2011) (103)
- PAX6 expression in the developing human eye (1999) (102)
- Neuronal Survival Factor from Bovine Brain Is Identical to Neuron‐Specific Enolase (1991) (102)
- Induction of CHOP and apoptosis by nitric oxide in p53‐deficient microglial cells (2001) (100)
- Ability of rat microglia to uptake extracellular glutamate (2001) (100)
- Production and secretion of plasminogen in cultured rat brain microglia (1992) (98)
- Akt activation is involved in P2Y12 receptor‐mediated chemotaxis of microglia (2008) (96)
- Familial clustering of situs inversus totalis, and asplenia and polysplenia syndromes. (1983) (95)
- Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease (1998) (95)
- Molecular cloning of rat growth inhibitory factor cDNA and the expression in the central nervous system. (1993) (91)
- Microglial Ca2+-Activated K+ Channels Are Possible Molecular Targets for the Analgesic Effects of S-Ketamine on Neuropathic Pain (2011) (91)
- Cyclosporin A enhances the survivability of mouse cerebral cortex grafted into the third ventricle of rat brain (1985) (85)
- Direct interaction of post‐synaptic density‐95/Dlg/ZO‐1 domain‐containing synaptic molecule Shank3 with GluR1 α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid receptor (2006) (85)
- Molecular Characterization of Mammalian Homologues of Class C Vps Proteins That Interact with Syntaxin-7* (2001) (84)
- Neuroprotective effect of sonic hedgehog up‐regulated in Schwann cells following sciatic nerve injury (2008) (84)
- Ceramide activates microglia to enhance the production/secretion of brain‐derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro (2002) (83)
- Involvement of amyloid precursor protein in functional synapse formation in cultured hippocampal neurons (1998) (81)
- Neurotrophic and neuroprotective effects of neuron-specific enolase on cultured neurons from embryonic rat brain (1995) (81)
- Metabolic mapping of chick brain after imprinting using [14C]2-deoxyglucose technique (1979) (80)
- NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus (2009) (80)
- Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain (2011) (79)
- Olfactory receptor neurons prevent dissemination of neurovirulent influenza A virus into the brain by undergoing virus-induced apoptosis. (2002) (78)
- Generation and characterization of a microglial cell line, MG5, derived from a p53‐deficient mouse (1997) (76)
- Impairment of in vivo calcium signaling in amyloid plaque-associated microglia (2014) (75)
- The amino-terminal region of amyloid precursor protein is responsible for neurite outgrowth in rat neocortical explant culture. (1997) (74)
- Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease (2012) (71)
- Neuronal regulation by which microglia enhance the production of neurotrophic factors for GABAergic, catecholaminergic, and cholinergic neurons (2007) (70)
- Developmental studies on the cerebellum from reeler mutant mouse in vivo and in vitro. (1980) (69)
- Adenosine A3 receptor is involved in ADP‐induced microglial process extension and migration (2012) (67)
- Autotaxin expression is enhanced in frontal cortex of Alzheimer-type dementia patients (2006) (67)
- Fibulin‐1 binds the amino‐terminal head of β‐amyloid precursor protein and modulates its physiological function (2001) (66)
- Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells. (2001) (66)
- Possible association of platelet-derived growth factor (PDGF) with the appearance of reactive astrocytes following brain injury in situ (1986) (63)
- The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure. (2005) (63)
- The Upregulated Expression of Sonic Hedgehog in Motor Neurons after Rat Facial Nerve Axotomy (2004) (63)
- Intact microglia are cultured and non-invasively harvested without pathological activation using a novel cultured cell recovery method. (2001) (61)
- Microglia-derived plasminogen enhances neurite outgrowth from explant cultures of rat brain (1993) (60)
- Early immunohistochemical detection of axonal damage and glial activation in extremely immature brains with periventricular leukomalacia. (2001) (60)
- Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms (2017) (59)
- NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted‐In‐Schizophrenia 1 (DISC1) (2011) (56)
- Laminin α1 is essential for mouse cerebellar development. (2012) (56)
- Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane. (1994) (55)
- Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis (2010) (55)
- Impaired microglial activation in the brain of IL-18-gene-disrupted mice after neurovirulent influenza A virus infection. (2001) (55)
- Inhibition of NMDA receptors induces delayed neuronal maturation and sustained proliferation of progenitor cells during neocortical development (2003) (54)
- BK channels in microglia are required for morphine-induced hyperalgesia (2016) (53)
- Early axonal and glial pathology in fetal sheep brains with leukomalacia induced by repeated umbilical cord occlusion (1999) (53)
- Rat primary cultured microglia express glial cell line-derived neurotrophic factor receptors (1999) (52)
- Novel variants of the SHANK3 gene in Japanese autistic patients with severe delayed speech development (2011) (51)
- Induction of Urokinase‐Type Plasminogen Activator in Rat Facial Nucleus by Axotomy of the Facial Nerve (1996) (51)
- Fyn Is Required for Haloperidol-induced Catalepsy in Mice* (2006) (49)
- Expression and distribution of low density lipoprotein receptor-related protein mRNA in the rat central nervous system. (1995) (49)
- Spatial and temporal aspects of Ca2+ signaling mediated by P2Y receptors in cultured rat hippocampal astrocytes. (2002) (49)
- Protein kinase Cα requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor α in lipopolysaccharide-stimulated microglia (2004) (48)
- Plasminogen promotes the development of rat mesencephalic dopaminergic neurons in vitro. (1993) (48)
- Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy (2008) (48)
- Characterization of microglia isolated from a primary culture of embryonic rat brain by a simplified method (1989) (47)
- Tetrahydrobiopterin-dependent functional recovery in 6-hydroxydopamine-treated rats by intracerebral grafting of fibroblasts transfected with tyrosine hydroxylase cDNA. (1992) (47)
- Neurochemical and morphological studies on the myelin of peripheral nervous system from Shiverer mutant mice: absence of basic proteins common to central nervous system (1981) (47)
- Microglia‐Derived Elastase Produces a Low‐Molecular‐Weight Plasminogen that Enhances Neurite Outgrowth in Rat Neocortical Explant Cultures (1993) (46)
- 22q13 microduplication in two patients with common clinical manifestations: A recognizable syndrome? (2007) (46)
- Specific inhibitor for prolyl endopeptidase suppresses the generation of amyloid beta protein in NG108-15 cells. (1997) (45)
- Novel Domain-Specific Actions of Amyloid Precursor Protein on Developing Synapses (1998) (45)
- Synthesis of l‐3,4‐Bihydroxyphenylalanine by Tyrosine Hydroxylase cDNA‐Transfected C6 Cells: Application for Intracerebral Grafting (1989) (45)
- Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret (2010) (45)
- Interleukin-2 enhances the viability of primary cultured rat neocortical neurons (1993) (45)
- Pharmacological detection of AMPA receptor heterogeneity by use of two allosteric potentiators in rat hippocampal cultures (1998) (44)
- The Alzheimer's disease drug memantine increases the number of radial glia‐like progenitor cells in adult hippocampus (2009) (44)
- Time‐dependent enhancement of hippocampus‐dependent memory after treatment with memantine: Implications for enhanced hippocampal adult neurogenesis (2014) (44)
- Nonparticipation of nuclear factor kappa B (NFκB) in the signaling cascade of c-Jun N-terminal kinase (JNK)- and p38 mitogen-activated protein kinase (p38MAPK)-dependent tumor necrosis factor alpha (TNFα) induction in lipopolysaccharide (LPS)-stimulated microglia (2006) (44)
- Upregulated Expression of Iba1 Molecules in the Central Nervous System of Mice in Response to Neurovirulent Influenza A Virus Infection (2000) (43)
- Morphological and Biochemical Studies on the Cerebral Cortex from Reeler Mutant Mice: Development of Cortical Layers and Metabolic Mapping by the Deoxyglucose Method (1980) (42)
- Macrophage‐colony stimulating factor as an inducer of microglial proliferation in axotomized rat facial nucleus (2010) (42)
- Effects of Bovine Growth Hormone on the Retarded Cerebral Development Induced by Neonatal Hydrocortisone Intoxication (1982) (41)
- α2-Macroglobulin is an astroglia-derived neurite-promoting factor for cultured neurons from rat central nervous system (1990) (41)
- Early-life stress increases the motility of microglia in adulthood (2015) (41)
- Functional roles of microglia in the central nervous system. (1998) (39)
- Molecular Cloning and Characterization of Annexin V‐Binding Proteins with Highly Hydrophilic Peptide Structure (1996) (38)
- Increased cerebrospinal fluid fibrinogen in major depressive disorder (2015) (38)
- Transplantation of bulk-separated oligodendrocytes into the brains of shiverer mutant mice: Immunohistochemical and electron microscopic studies on the myelination (1986) (38)
- Stereotaxic Atlas of the Marmoset Brain (2010) (38)
- Distribution of the galectin-1 mRNA in the rat nervous system: its transient upregulation in rat facial motor neurons after facial nerve axotomy (2004) (38)
- Neuronal stimulation leading to upregulation of glutamate transporter-1 (GLT-1) in rat microglia in vitro (2008) (37)
- Expression, purification, and neurotrophic activity of amyloid precursor protein-secreted forms produced by yeast. (1995) (37)
- NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1) (2011) (37)
- Ca(2+) spiking activity caused by the activation of store-operated Ca(2+) channels mediates TNF-α release from microglial cells under chronic purinergic stimulation. (2013) (37)
- Robo1 regulates the migration and laminar distribution of upper-layer pyramidal neurons of the cerebral cortex. (2013) (36)
- GABAergic activities enhance macrophage inflammatory protein‐1α release from microglia (brain macrophages) in postnatal mouse brain (2009) (36)
- Neuronal adhesion molecule telencephalin induces rapid cell spreading of microglia (1999) (34)
- Iba1-expressing microglia respond to herpes simplex virus infection in the mouse trigeminal ganglion. (2003) (34)
- Hepatocyte Growth Factor-induced Differential Activation of Phospholipase Cγ1 and Phosphatidylinositol 3-Kinase Is Regulated by Tyrosine Phosphatase SHP-1 in Astrocytes* (2000) (33)
- Allograft inflammatory factor 1 is a regulator of transcytosis in M cells (2017) (33)
- RNA‐sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease (2015) (32)
- Cerebellar Hypoplasia in the Gunn Rat with Hereditary Hyperbilirubinemia: Immunohistochemical and Neurochemical Studies (1980) (32)
- Ubiquitylation and Degradation of Serum-inducible Kinase by hVPS18, a RING-H2 Type Ubiquitin Ligase* (2005) (31)
- Receptor related to tyrosine kinase RYK regulates cell migration during cortical development. (2005) (31)
- IRF8 is a transcriptional determinant for microglial motility (2014) (30)
- Synthetic peptide corresponding to 30 amino acids of the C-terminal of neuron-specific enolase promotes survival of neocortical neurons in culture. (1994) (29)
- The effect of a secreted form of β‐amyloid‐precursor protein on intracellular Ca2+ increase in rat cultured hippocampal neurones (1998) (29)
- Differential suppression of endotoxin-inducible inflammatory cytokines by nuclear factor kappa B (NFκB) inhibitor in rat microglia (2006) (29)
- Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling (2017) (29)
- Expression of the α2-macroglobulin-encoding gene in rat brain and cultured astrocytes (1994) (29)
- Accumulating Microglia Phagocytose Injured Neurons in Hippocampal Slice Cultures: Involvement of p38 MAP Kinase (2012) (28)
- Selective Activation of Phospholipase Cγ1 and Distinct Protein Kinase C Subspecies in Intracellular Signaling by Hepatocyte Growth Factor/Scatter Factor in Primary Cultured Rat Neocortical Cells (1998) (28)
- Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia. (2004) (28)
- Monoubiquitylation of GGA3 by hVPS18 regulates its ubiquitin-binding ability. (2006) (28)
- Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol. (2002) (28)
- Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons (1994) (28)
- Tetrahydrobiopterin-dependent production of l-DOPA in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: future use for intracerebral grafting (1990) (27)
- Characteristic response of astrocytes to plasminogen/plasmin to upregulate transforming growth factor beta 3 (TGFβ3) production/secretion through proteinase-activated receptor-1 (PAR-1) and the downstream phosphatidylinositol 3-kinase (PI3K)-Akt/PKB signaling cascade (2009) (27)
- Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Chick Retina (1983) (27)
- Neurotrophic effects of annexin V on cultured neurons from embryonic rat brain (1994) (27)
- Slo2 sodium-activated K+ channels bind to the PDZ domain of PSD-95. (2003) (27)
- Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations. (2007) (26)
- Transcranial Direct Current Stimulation (tDCS) Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice (2019) (25)
- De novo production of α2-macroglobulin in cultured astroglia from rat brain (1992) (25)
- X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding. (2006) (25)
- Plasminogen mediates an interaction between microglia and dopaminergic neurons. (1994) (24)
- Increased activity of ornithine decarboxylase in goldfish following optic nerve crush. (1981) (23)
- Activation of microglia by endotoxin suppresses the secretion of glial cell line–derived neurotrophic factor (GDNF) through the action of protein kinase Cα (PKCα) and mitogen‐activated protein kinases (MAPKS) (2008) (23)
- Glial conditioned medium alters the expression of amyloid precursor protein in SH-SY5Y neuroblastoma cells. (1994) (22)
- Retinoic acid enhances the secretion of plasminogen from cultured rat microglia (1992) (22)
- Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex. (2003) (21)
- Plasminogen‐binding protein associated with the plasma membrane of cultured embryonic rat neocortical neurons (1993) (21)
- Subcultured astrocytes suppress the proliferation of neuroblasts in vitro (1986) (21)
- Role of cell cycle‐associated proteins in microglial proliferation in the axotomized rat facial nucleus (2012) (21)
- Secreted form of β-amyloid precursor protein activates protein kinase C and phospholipase Cγ1 in cultured embryonic rat neocortical cells (1998) (20)
- Uridine Metabolism in the Goldfish Retina During Optic Nerve Regeneration: Whole Retina Studies (1981) (20)
- Immunohistochemical studies on mouse cerebral cortex grafted into the third ventricle of rats treated with cyclosporin A (1985) (20)
- Uridine Metabolism in the Goldfish Retina During Optic Nerve Regeneration: Cell‐Free Preparations (1981) (19)
- Dissociation of enhanced ornithine decarboxylase activity and optic nerve regeneration in goldfish. (1982) (19)
- Ornithine decarboxylase activity in retinal explants of goldfish undergoing optic nerve regeneration. (1981) (19)
- Response of Microglia to Brain Injury (2004) (19)
- Neurochemical Characteristics of Myelin‐like Structure in the Chick Retina (1980) (19)
- Identification of two novel Shank3 transcripts in the developing mouse neocortex (2014) (18)
- Activation of microglia with lipopolysaccharide leads to the prolonged decrease of conventional protein kinase C activity. (2003) (18)
- Changes in ganglioside composition and morphological features during the development of cultured astrocytes from rat brain (1989) (18)
- Septal deafferentation enhances the neurotrophic effects of rat hippocampus on cultured neural cells from the central nervous system (1986) (18)
- Expression of Ia antigen on vascular endothelial cells in mouse cerebral tissue grafted into the third ventricle of rat brain (1989) (18)
- Characterization of brain microglia and the biological significance in the central nervous system. (1993) (18)
- Segmented Iba1-Positive Processes of Microglia in Autism Model Marmosets (2019) (17)
- Association of osteopontin with ischemic axonal death in periventricular leukomalacia (2000) (17)
- Neuroprotective Roles of Microglia in the Central Nervous System (2002) (17)
- Immunological rejection of grafted tissue in xenogeneic neural transplantation. (1990) (17)
- Mosaic reconstruction of blood vessels in mouse neocortical tissue transplanted into the third ventricle of rat brain (1989) (17)
- Up-regulation of glutamine synthesis in microglia activated with endotoxin (2015) (16)
- Functional down-regulation of axotomized rat facial motoneurons (2013) (16)
- Immunohistochemical and Biochemical Analyses of Development of Nervous System of Mutant Mice (Reeler and Shiverer) (1982) (15)
- Plasminogen enhances the secretion of plasminogen activator inhibitor-1 from cultured rat astrocytes (2000) (15)
- Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: the aromatic group is essential for the activity. (2002) (15)
- Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Central Nervous System of the Jimpy and the Normal Mouse (1985) (14)
- In vitro proliferation of axotomized rat facial nucleus‐derived activated microglia in an autocrine fashion (2006) (14)
- Structure of rat annexin V gene and molecular diversity of its transcripts. (1995) (14)
- Modification of a fiber protein in an adenovirus vector improves in vitro gene transfer efficiency to the mouse microglial cell line (2002) (13)
- Real‐time, two‐dimensional visualization of ischaemia‐induced glutamate release from hippocampal slices (2001) (13)
- Disorders in myelination in the twitcher mutant: immunohistochemical and biochemical studies. (1985) (13)
- Expression of receptor tyrosine kinase RYK in developing rat central nervous system. (1999) (12)
- Immunohistochemical study on oxytocin-like substance in the human placenta. (1984) (12)
- Nitric oxide inhibits the proliferation of murine microglial MG5 cells by a mechanism involving p21 but independent of p53 and cyclic guanosine monophosphate (2001) (12)
- Effect of food restriction on serotonin metabolism in rat brain (2004) (12)
- Inhibition of N-methyl-d-aspartate receptor activity resulted in aberrant neuronal migration caused by delayed morphological development in the mouse neocortex (2010) (12)
- Superoxide anion contributes to the induction of tumor necrosis factor alpha (TNFα) through activation of the MKK3/6-p38 MAPK cascade in rat microglia (2011) (11)
- Axonal injury in experimental herpes simplex encephalitis (2005) (11)
- Dissociation of neurite-promoting activity and protease-inhibiting function of a 2-macroglobulin in culture (1991) (11)
- Immunohistochemical studies on synapse formation by embryonic cerebellar tissue transplanted into the cerebellum of the weaver mutant mouse (1987) (11)
- Expression of the alpha 2-macroglobulin-encoding gene in rat brain and cultured astrocytes. (1994) (11)
- Additive dominant effect of a SOX10 mutation underlies a complex phenotype of PCWH (2015) (11)
- Generation of microglial cell lines by transfection with simian virus 40 large T gene (1992) (10)
- Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine (2022) (9)
- Gene expression profiles in the common marmoset brain determined using a newly developed common marmoset-specific DNA microarray (2010) (9)
- Impaired Development of Rat Cerebellum Induced by Neonatal Injection of the Glycoprotein Synthesis Inhibitor, Tunicamycin (1985) (9)
- The effect of arcuate nucleus transplantation on the development of the anterior pituitary in monosodium glutamate-treated rats (1986) (9)
- Establishment of CHO cell lines expressing four N‐methyl‐D‐aspartate receptor subtypes and characterization of a novel antagonist PPDC (2001) (9)
- Alpha 2-macroglobulin is an astroglia-derived neurite-promoting factor for cultured neurons from rat central nervous system. (1990) (9)
- Axotomy-dependent urokinase induction in the rat facial nucleus: possible stimulation of microglia by neurons (2005) (9)
- Involvement of nitric oxide in the induction of interleukin-1 beta in microglia (2015) (9)
- Cell-type-specific expression of protein tyrosine kinase-related receptor RYK in the central nervous system of the rat. (2002) (8)
- Apoptotic cell death of a temperature-sensitive central neuronal cell line (1995) (8)
- Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro (2010) (8)
- Enhancement of urokinase-type plasminogen activator (uPA) secretion, but not that of substrate plasminogen (PGn), by rat microglia stimulated with neuronal conditioned medium (2005) (8)
- Response of the GABAergic System to Axotomy of the Rat Facial Nerve (2018) (7)
- [Regulation of microglial cell function by ATP]. (2001) (7)
- Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats (2012) (7)
- [In vivo characterization of sonic hedgehog in the peripheral nerve regeneration]. (2007) (7)
- Ceramide‐enhanced urokinase‐type plasminogen activator (uPA) release is mediated by protein kinase C in cultured microglia (2000) (7)
- Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells. (2007) (7)
- Ceramide-enhanced urokinase-type plasminogen activator (uPA) release is mediated by protein kinase C in cultured microglia. (2000) (7)
- Transgenic monkey model of the polyglutamine diseases recapitulating progressive neurological symptoms and polyglutamine protein inclusions (2017) (7)
- Possible synapse formation by embryonic cerebellar tissue grafted into the cerebellum of the weaver mutant mouse. (1988) (7)
- Microglioma in a child - a further case in support of the microglioma entity and distinction from histiocytic sarcoma. (2016) (6)
- 2‐Deoxyglucose Incorporation in the Cerebellum of Weaver and Nervous Mutant Mice (1981) (6)
- Functional implication of secretory proteases derived from microglia in the central nervous system. (1996) (6)
- Production of Monoclonal Antibody to 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase from Bovine Cerebral White Matter (1986) (6)
- Effect of (6R)- and (6S)-tetrahydrobiopterin on L-3,4-dihydroxyphenylalanine (DOPA) formation in NRK fibroblasts transfected with human tyrosine hydroxylase type 2 cDNA (1990) (6)
- Transient down-regulation and restoration of glycogen synthase levels in axotomized rat facial motoneurons (2014) (6)
- Reorganization of cerebellar cell suspension transplanted into the weaver mutant cerebellum and immunohistochemical detection of synaptic formation (1988) (5)
- Expression of the mammalian homologue of vacuolar protein sorting 16 (Vps16p) in the mouse and rat brain (2004) (5)
- Synthesis of (1S,2R)-1-phenyl-2-[(S)-1-aminoalkyl]-N,N-diethylcyclopropanecarboxamides as novel NMDA receptor antagonists having a unique NMDA receptor subtype selectivity (2002) (5)
- ATP stimulates CA2+-dependent plasminogen release from cultured microglia (1998) (5)
- Microglia derived from the axotomized adult rat facial nucleus uptake glutamate and metabolize it to glutamine in vitro (2017) (5)
- Transfection of Tyrosine Hydroxylase cDNA into C6 Cells (1988) (5)
- Disorders in myelination in thetwitcher mutant: Immunohistochemical and biochemical studies (1985) (4)
- Neurochemical studies on the inverted laminar cerebral cortex of the reeler mutant mouse (1979) (4)
- Microglia-derived plasminogen has neurotrophic effects on the CNS neurons in vitro. (1994) (4)
- De novo production of alpha 2-macroglobulin in cultured astroglia from rat brain. (1992) (4)
- Secreted form of beta-amyloid precursor protein activates protein kinase C and phospholipase Cgamma1 in cultured embryonic rat neocortical cells. (1998) (3)
- Neuroprotective action of a novel compound–M50463–in primary cultured neurons 1 Published on the World Wide Web on 11 November 1998. 1 (1999) (3)
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- Control of the Common Cutworm, Spodoptera litura (FABRICIUS), by Overnight Illumination with Yellow Fluorescent. Lamps (1992) (2)
- Microglial Response to Injury (2009) (2)
- Fibulin-1 binds the amino-terminal head of β-amyloid precursor protein and modulates its phyiological function (2000) (2)
- The interaction of mammalian Class C Vps with nSec-1/Munc18-a and syntaxin 1A regulates pre-synaptic release. (2006) (2)
- Neurochemical and behavioral studies on the experimental phenylketonuric rats. (1979) (2)
- Accumulation of glycogen in axotomized adult rat facial motoneurons (2015) (2)
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- Application of Optical Radiant Technology for the High Efficient Plant Production (1997) (1)
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- Crystallization and preliminary X-ray crystallographic analysis of macrophage/microglia-specific calcium-binding protein Iba1. (2004) (1)
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- Effects of glycoprotein synthesis inhibitor on myelination in rat cerebellum (1985) (1)
- P1-110: Microglia ablation does not alter plaque formation and maintenance in a mouse model of cerebral amyloidosis (2008) (1)
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- Hypovascular glial overgrowth from the optic nerve head in foetuses of 16 weeks gestation (2009) (1)
- Neurochemical studies on the neuronal survival factors in rat hippocampus (1987) (1)
- Changes of Photosynthetic Characteristics According to Light Quality in Cultured Period (2002) (1)
- Requirements for Hazard Assessment of Chemical Substances and the Nervous System (2005) (0)
- Effect of interleukin-2 on MPP+-induced dopaminergic cell damage in rat mesencephalic cultures (1994) (0)
- Part II: Serial Parasagittal Sections (2010) (0)
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- Experimental Study of the Effects of Artificial Lighting on the Maturing of Figs (2002) (0)
- Effect of plasminogen on the production of PAI from cultured astrocytes (1998) (0)
- Morphological abnormalities of rat cerebellum induced by neonatal injection of the inhibitor of glycoprotein synthesis tunicamycin (1984) (0)
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- Administration of NMDA receptor antagonist causes down-regulation of DISC1 expression and over migration of newly generated neurons in the adult hippocampus (2010) (0)
- Interaction of Microglia with Neurons and Astrocytes Under Lesioned Neuronal Conditions (2012) (0)
- Studies on the plasminogen binding proteins on neuronal membrane (1992) (0)
- Experimental Studies on the Supplemental Lighting for Vegetable Seedlings (1999) (0)
- Regulation of microglial proliferation in axotomized rat facial nucleus: Effects of glial cell line-derived neurotrophic factor (GDNF) (2010) (0)
- Association of mitogen-activated protein kinase with upregulation of plasminogen activator inhibitor-1 in rat astrocytes stimulated with plasminogen (2009) (0)
- Biochemical characterization of neuronal survival factors from bovine hippocampus (1989) (0)
- Crystal structure of microglia-specific protein, Iba1 (2006) (0)
- INTERNATIONAL SYMPOSIUM Functional Implication of Secretory Proteases Derived from Microglia in the Central Nervous System (2008) (0)
- Statistical Consideration of Relationship between Solar Radiant Quantity and Fig Maturation (1998) (0)
- Suppression of lipopolysaccharide-dependent tumor necrosis factor alpha induction in rat microglia, in which protein kinase C alpha is down-regulated. (2003) (0)
- Real time imaging study on injury-induced microglial activation in the hippocampal slice culture (2007) (0)
- [Intercellular interaction between neuron and glial cells--from the aspect of motoneuron-regeneration system]. (1998) (0)
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- Neurochemical studies on the rat hippocampal neurotrophic factors (1987) (0)
- Microglial surveillance of the brain is regulated by an anaesthetic-sensitive two-pore domain K+ channel (2017) (0)
- Robo1 regulates the morphological development of pyramidal neurons in the mouse neocortex (2010) (0)
- Appearance of phagocytic microglia in facial nuclei after nerve avulsion in presymptomatic ALS model rats (2009) (0)
- Part I: Serial Coronal Sections (2010) (0)
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- Enhancement of hippocampal adult neurogenesis by memantine treatment improves hippocampus-dependent learning and memory (2011) (0)
- NMDA receptor and schizophrenia – From the perspective of neurogenesis (2009) (0)
- Development, regeneration, sprouting and trophic factorsFunctional domains of the neural adhesion molecule L1 determine growth cone morphology and correlate with neuronal differentiation (1989) (0)
- S2-3 Function of microglia on the process of neuronal repair (1996) (0)
- Cultured rat astrocytes produce alpha2-macroglobulin de novo (1991) (0)
- 1302 Interleukin-2 protects mpp+-induced cell death of dopaminergic neurons in vitro (1993) (0)
- Involvement of Ibal protein in membrane ruffling and phagocytosis of microglia (2000) (0)
- Modeling for a complex neurocristopathy, PCWH, using mutant Sox10 BAC transgenic mice (2009) (0)
- IRF8 is a transcriptional determinant for microglial motility (2014) (0)
- 320 Involvement of amyloid precursor protein in synaptogenesis (1997) (0)
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- Upregulation of PEDF by the Alzheimer's disease drug memantine is involved in the increased neurogenesis of adult mouse hippocampus (2009) (0)
- Parasagittal Plane: Section 14 (2010) (0)
- NEUROTROPHINS REGULATE THE FUNCTION OF MICROGLIA (1997) (0)
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- Regulation of microglial proliferation by cell cycle-associated proteins in the transected rat facial nucleus (2011) (0)
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- Coronal Plane: Section 61 (2010) (0)
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- The role of Roundabout1 (Robo1) in layer formation, axonal and dendritic outgrowth in the developing mouse neocortex (2009) (0)
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- Iba1-EGFPトランスジェニックマウスの作製;ミクログリアの可視化 (2004) (0)
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- [Figure], Parasagittal Plane: Section 14 - Immunohistochemically Stained with Anti-Calbindin Antibody (2010) (0)
- Experimental Studies on the Supplemental Lighting for Vegetable Seedlings at Winter Season (2000) (0)
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- 1216 Trophic effect of kringle proteins secreted from microglia (1996) (0)
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- CCDC 176579: Experimental Crystal Structure Determination (2002) (0)
- 1301 α2-macrogulobulin gene expression in rat cultured astroglia and brain (1993) (0)
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- Fyn protein tyrosine kinase as a target for antipsychotic drugs (2007) (0)
- 812 The neurotrophic effects of the low molecular weight form of plasminogen (1993) (0)
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- Measurement of the Photosynthetics of Cladosiphon okamuranus TOKIDA (2002) (0)
- Nicotine receptor and amyloid burden for frontal activation in Alzheimer disease (0)
- Expression of class II antigen on the mouse brain xenograft (1988) (0)
- 816 Secreted form of β-amyloid precursor protein activates protein kinase C in cultured rat neocortical neurons (1997) (0)
- Early-life stress increases the motility of microglia in adulthood (2015) (0)
- Microglia Secrete Plasminogen Which Enhances the Maturation of Mesencephalic Dopaminergic Neurons in Vitro (1995) (0)
- 610 Telencephalin induces spreading of microglia (1997) (0)
- Formation and maintenance of β-amyloid plaques in the absence of microglia (2009) (0)
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