Shiranee Sriskandan
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Professor of Infectious Diseases
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Shiranee Sriskandan's Degrees
- PhD Infectious Diseases Imperial College London
Why Is Shiranee Sriskandan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Shiranee Sriskandan is a British academic who is Professor of Infectious Diseases at Imperial College London and Honorary Consultant at Hammersmith Hospital. Her research considers how Gram-positive bacteria cause disease, with a particular focus on the bacteria Streptococcus pyogenes.
Shiranee Sriskandan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mapping the human genetic architecture of COVID-19 (2021) (455)
- The immunology of sepsis (2008) (306)
- Mammalian Toll‐like receptors: to immunity and beyond (2005) (235)
- Specific C-terminal cleavage and inactivation of interleukin-8 by invasive disease isolates of Streptococcus pyogenes. (2005) (196)
- Gram-positive sepsis. Mechanisms and differences from gram-negative sepsis. (1999) (176)
- The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. (2008) (170)
- Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis. (1997) (151)
- Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study (2021) (136)
- Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom (2015) (118)
- The Mechanism of Superantigen-Mediated Toxic Shock: Not a Simple Th1 Cytokine Storm1 (2005) (114)
- Superantigens and Streptococcal Toxic Shock Syndrome (2003) (100)
- Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study (2021) (98)
- Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK (2021) (94)
- The Bacterial Superantigen Streptococcal Mitogenic Exotoxin Z Is the Major Immunoactive Agent of Streptococcus pyogenes1 (2002) (90)
- Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract (2010) (87)
- Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis (2018) (86)
- Detection of circulating bacterial superantigen and lymphotoxin-a in patients with streptococcal toxic-shock syndrome (1996) (85)
- Streptococcus pyogenes: Insight into the function of the streptococcal superantigens. (2007) (82)
- Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation. (2006) (81)
- Enhanced susceptibility to superantigen-associated streptococcal sepsis in human leukocyte antigen-DQ transgenic mice. (2001) (81)
- The pathogenesis of septic shock. (1995) (79)
- Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study (2021) (77)
- Invasive Disease and Toxic Shock due to Zoonotic Streptococcus suis: An Emerging Infection in the East? (2006) (76)
- Impact of immunization against SpyCEP during invasive disease with two streptococcal species: Streptococcus pyogenes and Streptococcus equi (2009) (73)
- Comparative effects of clindamycin and ampicillin on superantigenic activity of Streptococcus pyogenes. (1997) (73)
- HLA Class II Polymorphisms Determine Responses to Bacterial Superantigens1 (2004) (73)
- Emerging role of the interleukin-8 cleaving enzyme SpyCEP in clinical Streptococcus pyogenes infection. (2009) (71)
- Guidelines for prevention and control of group A streptococcal infection in acute healthcare and maternity settings in the UK. (2012) (69)
- Pro-inflammatory mechanisms in sepsis. (2011) (68)
- Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma. (1996) (67)
- Streptococcal pyrogenic exotoxin A release, distribution, and role in a murine model of fasciitis and multiorgan failure due to Streptococcus pyogenes. (1996) (66)
- Growth-Phase-Dependent Expression of Virulence Factors in an M1T1 Clinical Isolate of Streptococcus pyogenes (1999) (65)
- New understandings in Streptococcus pyogenes (2011) (65)
- Toll-like receptor 2 is essential for the sensing of oxidants during inflammation. (2009) (65)
- Superantigen recognition by HLA class II on monocytes up-regulates toll-like receptor 4 and enhances proinflammatory responses to endotoxin. (2005) (64)
- Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020 (2020) (60)
- Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study (2019) (60)
- In vivo quantification of human pulmonary beta-adrenoceptors: effect of beta-agonist therapy. (1996) (59)
- Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle. (2005) (59)
- Mitogenic factor (MF) is the major DNase of serotype M89 Streptococcus pyogenes. (2000) (58)
- Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK (2021) (56)
- Differential effects of Gram‐positive versus Gram‐negative bacteria on NOSII and TNFα in macrophages: role of TLRs in synergy between the two (2006) (56)
- The contribution of group A streptococcal virulence determinants to the pathogenesis of sepsis (2013) (55)
- Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection (2013) (54)
- Natural Exposure to Cutaneous Anthrax Gives Long-Lasting T Cell Immunity Encompassing Infection-Specific Epitopes (2010) (53)
- High prevalence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacteriaceae in the UK and Ireland. (2018) (53)
- RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A Streptococci (2013) (52)
- Molecular analysis of the role of streptococcal pyrogenic exotoxin A (SPEA) in invasive soft‐tissue infection resulting from Streptococcus pyogenes (1999) (50)
- Working towards a group A streptococcal vaccine: report of a collaborative Trans-Tasman workshop. (2014) (49)
- COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study (2021) (49)
- Roles of the Alternative Complement Pathway and C1q during Innate Immunity to Streptococcus pyogenes (2006) (45)
- Molecular Analysis of an Outbreak of Lethal Postpartum Sepsis Caused by Streptococcus pyogenes (2013) (43)
- Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase (2017) (42)
- Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study (2021) (42)
- Cigarette smoke inhibits macrophage sensing of Gram‐negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress (2008) (42)
- Contact activation in shock caused by invasive group A Streptococcus pyogenes (2000) (41)
- Corynebacterium ulcerans cutaneous diphtheria. (2015) (40)
- Household transmission of invasive group A Streptococcus infections in England: a population-based study, 2009, 2011 to 2013 (2017) (40)
- Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014 (2016) (39)
- ELUCIDATION OF TOLL-LIKE RECEPTOR AND ADAPTER PROTEIN SIGNALING IN VASCULAR DYSFUNCTION INDUCED BY GRAM-POSITIVE STAPHYLOCOCCUS AUREUS OR GRAM-NEGATIVE ESCHERICHIA COLI (2007) (38)
- Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells (2008) (36)
- The TCR Vbeta signature of bacterial superantigens spreads with stimulus strength. (2006) (35)
- Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction (2015) (32)
- Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom (2018) (32)
- Current views of haemolytic streptococcal pathogenesis (2014) (31)
- Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK (2016) (29)
- Kallikrein-kinin system activation in streptococcal toxic shock syndrome. (2000) (28)
- The role of nitric oxide in experimental murine sepsis due to pyrogenic exotoxin A-producing Streptococcus pyogenes (1997) (28)
- Development of a multicomponent vaccine for Streptococcus pyogenes based on the antigenic targets of IVIG (2016) (27)
- Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin (2015) (27)
- A Truncation in the Regulator RocA Underlies Heightened Capsule Expression in Serotype M3 Group A Streptococci (2015) (27)
- Factors that impact on the burden of Escherichia coli bacteraemia: multivariable regression analysis of 2011-2015 data from West London. (2019) (25)
- Increased surface toll-like receptor 2 expression in superantigen shock (2008) (24)
- Hospital clusters of invasive Group B Streptococcal disease: a systematic review. (2019) (23)
- Sexual Dimorphism in Superantigen Shock Involves Elevated TNF-α and TNF-α–induced Hepatic Apoptosis (2007) (22)
- Pulmonary and cardiac beta-adrenoceptor density in vivo in asthmatic subjects. (1997) (22)
- Development of an opsonophagocytic killing assay for group a streptococcus. (2018) (22)
- Supervised machine learning for the prediction of infection on admission to hospital: a prospective observational cohort study (2019) (22)
- Serial Clustering of Late-Onset Group B Streptococcal Infections in the Neonatal Unit: A Genomic Re-evaluation of Causality (2018) (21)
- Invasive group A streptococcal infection in injecting drug users and non-drug users in a single UK city. (2007) (21)
- Severe group A streptococcal infections in mothers and their newborns in London and the South East, 2010–2016: assessment of risk and audit of public health management (2018) (20)
- Diffuse pneumonia associated with infectious mononucleosis: detection of Epstein-Barr virus in lung tissue by in situ hybridization. (1996) (20)
- The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression (2019) (19)
- Non-Invasive Monitoring of Streptococcus pyogenes Vaccine Efficacy Using Biophotonic Imaging (2013) (19)
- Pattern recognition receptors and interleukin‐8 mediate effects of Gram‐positive and Gram‐negative bacteria on lung epithelial cell function (2008) (18)
- Complementation of a speA negative Streptococcus pyogenes with speA: effects on virulence and production of streptococcal pyrogenic exotoxin A. (2001) (18)
- Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus (2017) (18)
- Repertoire of HLA-DR1-Restricted CD4 T-Cell Responses to Capsular Caf1 Antigen of Yersinia pestis in Human Leukocyte Antigen Transgenic Mice (2010) (18)
- Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell Immunity (2014) (18)
- A real-world evaluation of a Case-Based Reasoning algorithm to support antimicrobial prescribing decisions in acute care. (2020) (18)
- Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection (2020) (18)
- Gram-Positive and Gram-Negative Bacteria Synergize with Oxidants to Release CXCL8 from Innate Immune Cells (2008) (17)
- Isolation of vancomycin-resistant lactobacilli from three neutropenic patients with pneumonia (1993) (17)
- Bromine, bear-claw scratch fasciotomies, and the Eagle effect: management of group A streptococcal necrotising fasciitis and its association with trauma. (2015) (17)
- A Multispecies Cluster of GES-5 Carbapenemase–Producing Enterobacterales Linked by a Geographically Disseminated Plasmid (2019) (17)
- The value of open-source clinical science in pandemic response: lessons from ISARIC (2021) (17)
- Sexual dimorphism in superantigen shock involves elevated TNF-alpha and TNF-alpha induced hepatic apoptosis. (2007) (16)
- Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation (2012) (16)
- Humoral and cellular immunity to primary H1N1 infection in patients with hematologic malignancies following stem cell transplantation. (2011) (15)
- Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England (2021) (14)
- Streptococcal superantigen‐induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release† (2018) (14)
- Application of a rat model of streptococcal shock to evaluate on-line hemoperfusion and removal of circulating superantigens* (2003) (14)
- Nosocomial Outbreak of Drug-Resistant Streptococcus pneumoniae Serotype 9V in an Adult Respiratory Medicine Ward (2016) (13)
- Hypothermia in a child secondary to ibuprofen (2003) (13)
- Frequency of transmission, asymptomatic shedding, and airborne spread of Streptococcus pyogenes in schoolchildren exposed to scarlet fever: a prospective, longitudinal, multicohort, molecular epidemiological, contact-tracing study in England, UK (2022) (13)
- Panton–Valentine leucocidin expression by Staphylococcus aureus exposed to common antibiotics (2015) (13)
- Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR. (2019) (12)
- The nature of innate and adaptive interleukin‐17A responses in sham or bacterial inoculation (2012) (12)
- Respiratory syncytial virus infection in an adult with AIDS. (1993) (12)
- Modification of the classical Lancefield assay of group A streptococcal killing to reduce inter-donor variation (2016) (11)
- The cost of hospital care for management of invasive group A streptococcal infections in England (2014) (11)
- LYMPHOTOXIN-α (TNF-β) DURING SEPSIS (1996) (11)
- Aquagenic wrinkling of palms on exposure to alcohol gel (2011) (10)
- Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study (2022) (10)
- Sepsis: Precision-Based Medicine for Pregnancy and the Puerperium (2019) (10)
- Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes (2018) (10)
- Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes (2020) (9)
- An Epitope of Bacillus anthracis Protective Antigen That Is Cryptic in Rabbits May Be Immunodominant in Humans (2010) (9)
- Asymptomatic group A Streptococcal throat carriage in Royal Marines recruits and Young Officers. (2017) (9)
- A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP (2018) (9)
- Editorial Commentary: Step on the GAS: Are We Almost There for Clindamycin and Intravenous Immunoglobulin? (2014) (8)
- Exposure to anthrax toxin alters human leucocyte expression of anthrax toxin receptor 1 (2013) (8)
- C‐Terminal antibodies (CTAbs): A simple and broadly applicable approach for the rapid generation of protein‐specific antibodies with predefined specificity (2007) (8)
- A prospective surveillance study to determine the prevalence of 16S rRNA methyltransferase-producing Gram-negative bacteria in the UK. (2021) (8)
- Viridans streptococcal bacteraemia: a clinical survey. (1995) (8)
- Staphylococcus aureus colonisation and acquisition of skin and soft tissue infection amongst Royal Marines recruits: a prospective cohort study. (2020) (7)
- Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study (2022) (7)
- Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus (2016) (7)
- Clinical management and impact of scarlet fever in the modern era: findings from a cross-sectional study of cases in London, 2018–2019 (2021) (7)
- Delineating the impact of COVID-19 on antimicrobial resistance: An Indian perspective (2021) (7)
- Discovery and validation of a three-gene signature to distinguish COVID-19 and other viral infections in emergency infectious disease presentations: a case-control and observational cohort study (2021) (7)
- Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection (2019) (7)
- Two-year analysis of Clostridium difficile ribotypes associated with increased severity (2019) (7)
- Aggressive management of doxorubicin-induced cardiomyopathy associated with 'low' doses of doxorubicin. (1994) (7)
- Ebola and other viral haemorrhagic fevers: a local operational approach. (2014) (7)
- Lymphotoxin-alpha (TNF-beta) during sepsis. (1996) (7)
- β‐Haemolytic Streptococci (2006) (6)
- Transmission of SARS-CoV-2 by children attending school. Interim report on an observational, longitudinal sampling study of infected children, contacts, and the environment (2021) (6)
- Musculoskeletal side-effects of varicella (1997) (6)
- Transmission of SARS-CoV-2 by children to contacts in schools and households: a prospective cohort and environmental sampling study in London (2022) (6)
- Antiviral metabolite 3′-deoxy-3′,4′-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19 (2021) (6)
- Uncovering infant group B streptococcal (GBS) disease clusters in the UK and Ireland through genomic analysis: a population-based epidemiological study. (2020) (5)
- Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus (2019) (5)
- Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species (2021) (5)
- Cohort study protocol: Bioresource in Adult Infectious Diseases (BioAID) (2018) (5)
- Chapter 38 – Streptococcus pyogenes (2015) (5)
- Superantigens SPEA and SMEZ do not affect secretome expression in Streptococcus pyogenes. (2008) (5)
- Sampling and diversity of Escherichia coli from the enteric microbiota in patients with Escherichia coli bacteraemia (2019) (4)
- Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease (2020) (4)
- Impaired opsonization with complement and phagocytosis of Streptococcus pyogenes in sera from subjects with inherited C2 deficiency. (2010) (4)
- Treatment potential of pathogen-reactive antibodies sequentially purified from pooled human immunoglobulin (2019) (4)
- Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread (2018) (4)
- Novel 16S rRNA methyltransferase RmtE3 in Acinetobacter baumannii ST79. (2022) (4)
- Streptococcus pyogenes under pressure (2007) (3)
- Bacterial Lymphatic Metastasis in Infection and Immunity (2021) (3)
- Turner et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions” (2015) (3)
- Detection and characterisation of 16S rRNA methyltransferase-producing Pseudomonas aeruginosa from the UK and Republic of Ireland from 2003-2015. (2022) (3)
- The Role of Streptococcal Cell-Envelope Proteases in Bacterial Evasion of the Innate Immune System (2021) (3)
- Correction: Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection (2013) (3)
- Gram-positive bacterial infection in severe sepsis (2002) (3)
- Cystic fibrosis presenting with haematological abnormalities. (2006) (3)
- Corrigendum: Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK (2016) (3)
- LYMPHOTOXIN-a (TNF-b) DURING SEPSIS (1997) (3)
- Discovery and Validation of a 3-Gene Transcriptional Signature to Distinguish COVID-19 and Other Viral Infections from Bacterial Sepsis in Adults; A Case-Control then Observational Cohort Study (2021) (3)
- Nitric Oxide as a Mediator in Gram-Positive Sepsis (1995) (3)
- Alterations in chromosomal genes nfsA, nfsB, and ribE are associated with nitrofurantoin resistance in Escherichia coli from the United Kingdom. (2021) (3)
- Staphylococcus argenteus transmission among healthy Royal Marines: a molecular epidemiology case-study. (2021) (2)
- Lymphatic Metastasis of Virulent Extracellular Bacteria Drives Systemic Infection (2019) (2)
- The effect of trauma on invasive group A streptococcal disease (2015) (2)
- Necrotising soft-tissue infections. (2022) (2)
- Bacterial genotypic and patient risk factors for adverse outcomes in Escherichia coli bloodstream infections: a prospective molecular epidemiological study (2021) (2)
- Cell Envelope Proteinase A ( Streptococcus ) (2013) (2)
- Treatment potential of pathogen-reactive antibodies sequentially purified from pooled human immunoglobulin (2019) (1)
- Sampling and diversity of Escherichia coli from the enteric microbiota in patients with Escherichia coli bacteraemia (2019) (1)
- Characterisation of emergent toxigenic M1UK Streptococcus pyogenes and associated sublineages (2022) (1)
- Rapid screen for epithelial internalization of Tn917-mutagenized Streptococcus pyogenes. (2009) (1)
- Tumour Necrosis Factor as a Therapeutic Target in Sepsis (1994) (1)
- High frequency transmission, asymptomatic shedding, and airborne spread of Streptococcus pyogenes among schoolchildren exposed to scarlet fever: a longitudinal multi-cohort moleculo-epidemiological contact tracing study. (2021) (1)
- Correlates of immunity to Group A Streptococcus: a pathway to vaccine development (2023) (1)
- Time to negative throat culture following initiation of antibiotics for pharyngeal group A Streptococcus: a systematic review and meta-analysis to inform public health control measures (2022) (1)
- Immunity to bacterial infection (excluding mycobacteria) (PP-060) (2010) (1)
- Comment on “Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire” (2012) (1)
- Ongoing emergence of M1UK lineage among invasive group A streptococcus isolates in 2020 and use of allele-specific PCR (2022) (1)
- Modelling invasive group A streptococcal disease using bioluminescence (2018) (1)
- Symptom‐based case definitions for COVID‐19: Time and geographical variations for detection at hospital admission among 260,000 patients (2022) (1)
- Emerging Invasive Group A Streptococcus M1UK Lineage Detected by Allele-Specific PCR, England, 2020 (2023) (1)
- Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study (2022) (1)
- Streptococcus pyogenes superantigen SPEA expression suppresses all immunoglobulin classes in human tonsil explants (2010) (1)
- Identification of immunodominant T cell epitopes from anthrax protective antigen for inclusion in a rationally designed sub-unit based vaccine (2012) (0)
- IS1-related large-scale deletion of chromosomal regions harbouring oxygen-insensitive nitroreductase gene nfsB causes nitrofurantoin heteroresistance in Escherichia coli (2023) (0)
- Familial Transmission of emm12 Group A Streptococcus (2018) (0)
- Biological impact of a prevalent mutation in the major superantigen SMEZ in M3 serotype Streptococcus pyogenes (2007) (0)
- Susceptibility to superantigen-associated infection can be determined by MHC class II (1999) (0)
- Expression of toxic shock syndrome toxin-1 by epidemic meticillin-resistant Staphylococcus aureus 16 (2013) (0)
- Streptococcal lymphatic metastasis: Bacterial close encounters of the fourth kind (2016) (0)
- Non-menstrual toxic shock and the in vivo roles of seb and ivig (2008) (0)
- T cell epitope mapping anthrax: the detection of CD4 epitopes in lethal factor (2008) (0)
- Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes (2018) (0)
- Step on the GAS : AreWe Almost There for Clindamycin and Intravenous Immunoglobulin ? (2014) (0)
- DISCUSSION. PROFESSIONAL TRAINING AND STATUS OF CIVIL ENGINEERS. (1973) (0)
- ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19 (2022) (0)
- Modelling invasive group A streptococcal disease using bioluminescence (2018) (0)
- Immunodominant in Humans Antigen That Is Cryptic in Rabbits May Be Protective Bacillus anthracis An Epitope of (2014) (0)
- T cell homeostasis and memory (PP-059) (2010) (0)
- Table: Characteristics of patients with severe streptococcal disease, detection of spea from group A streptococcal isolates, and measurement of SPEA and LT-α in patient serum (1996) (0)
- Characterisation of Staphylococcus argenteus carried by healthy Royal Marines: a molecular epidemiology case-study (2021) (0)
- SARS-CoV-2 surface and air contamination in an acute healthcare setting during the first and second pandemic waves (2022) (0)
- The Synergistic up-Regulation of the Innate Immune Response by Endotoxin and Gram Positive Superantigens (2003) (0)
- Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation—author's response (2006) (0)
- 139 Steroid-free management of life-threatening haemophagocytic lymphohistiocytosis in the context of suspected lymphoproliferative disease and infection (2019) (0)
- P0134 Case-based reasoning for individualized antimicrobial selection: can intelligent decision support improve antimicrobial management? (2018) (0)
- P194 Molecular anatomy of invasive group A streptococcal (iGAS) isolates in England (2013) (0)
- COAGULATION ABNORMALITIES IN SEVERE STREPTOCOCCAL SHOCK SYNDROME: 74 (1999) (0)
- bradykinin antagonists may decrease mortality in patients with severe STSS. (2000) (0)
- endotoxin toll-like receptor 4 and enhances proinflammatory responses to Superantigen recognition by HLA class II on monocytes up-regulates (2010) (0)
- The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection (2023) (0)
- Responses to Bacterial Superantigens HLA Class II Polymorphisms Determine (2013) (0)
- Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus (2019) (0)
- Common genetic variants in the immunoglobulin heavy chain locus and their differential impact on group A streptococcal disease susceptibility: a comparative meta-analysis of genetic susceptibility studies (2017) (0)
- Diverse Genetic Determinants of Nitrofurantoin Resistance in UK Escherichia coli (2021) (0)
- Non-conventional serine protease activity of the CXC chemokine-cleaving streptococcal enzyme, SpyCEP (2021) (0)
- Advances in Multicomponent Reactions (2016) (0)
- Encompassing Infection-Specific Epitopes Gives Long-Lasting T Cell Immunity Natural Exposure to Cutaneous Anthrax (2010) (0)
- A Role for HLA Class II in Determining Susceptibility to Streptococcal Toxic Shock (2003) (0)
- A study of the superantigen streptococcal pyrogenic exotoxin A in invasive group A streptococcal disease. (1997) (0)
- Assay for superantigens. (2000) (0)
- Pseudotemporal whole blood transcriptional profiling of COVID-19 patients stratified by clinical severity reveals differences in immune responses and possible role of monoamine oxidase B (2022) (0)
- Group A Streptococcal puerperal Sepsis - A Look Back in Time (2009) (0)
- Skin and soft tissue infections (2000) (0)
- Time to negative throat culture following initiation of antibiotics for pharyngeal group A Streptococcus: a systematic review and meta-analysis up to October 2021 to inform public health control measures (2023) (0)
- Fever in a returned traveller (2009) (0)
- The involvement of TLR2 in activation of Tregs during Streptococcus pyogenes acute infection (2008) (0)
- Schools Transmission Study (COVID-19 and scarlet fever) (2020) (0)
- Regulatory T cells in acute Streptococcus pyogenes infection (2010) (0)
- Mouse Model of Streptococcal Fasciitis (1999) (0)
- Clinical and Translational Report Antiviral metabolite 3 -deoxy-3 ,4 -didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19 (2022) (0)
- Immunodominance in the Human Memory T Cells Correlates with + Naive CD4 Comment on ''Frequency of Epitope-Specific (2014) (0)
- Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease (2021) (0)
- Analysis of the CD4+ T cell response to Anthrax lethal Factor (2010) (0)
- Host genetic variants near the PAX5 gene locus associate with susceptibility to invasive group A streptococcal disease (2019) (0)
- The expression of TSST-1 by EMRSA-16 (2013) (0)
- Edinburgh Research Explorer Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus (2016) (0)
- Practice point 32 – Management of candiduria in the ICU (2010) (0)
- Nitrofurantoin-resistant Escherichia coli in the UK: genetic determinants, diversity, and undetected occurrences (2022) (0)
- The Role of T cells in Acute Streptococcus pyogenes Infection (2008) (0)
- The effect of trauma on invasive group A streptococcal (IGAS) disease (2015) (0)
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