Shirleen Roeder
Geneticist, Yale University Professor
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Biology
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(Suggest an Edit or Addition)According to Wikipedia, Glenna Shirleen Roeder is a geneticist known for identifying and characterizing the yeast genes that regulate the process of meiosis with particular emphasis on synapsis. Education and career Roeder has a B.Sc. from Dalhousie University and earned her Ph.D. in 1978 from the University of Toronto. Following her Ph.D. she was a postdoctoral fellow at Cornell University before moving to the faculty at Yale University in 1981. In 2001 she was named the Eugene Higgins Professor of Genetics in the Molecular, Cellular, and Developmental Biology Department at Yale University. Roeder retired in 2012 and, as of 2021, she is Professor Emeritus at Yale University.
Shirleen Roeder's Published Works
Published Works
- Subcellular localization of the yeast proteome. (2002) (740)
- Meiotic chromosomes: it takes two to tango. (1997) (613)
- ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis (1993) (610)
- Large-scale analysis of the yeast genome by transposon tagging and gene disruption (1999) (548)
- Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. (1994) (518)
- The pachytene checkpoint. (2000) (460)
- Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction (1994) (392)
- The Yeast Red1 Protein Localizes to the Cores of Meiotic Chromosomes (1997) (323)
- Crossover interference is abolished in the absence of a synaptonemal complex protein (1994) (310)
- Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I (1987) (298)
- Zip3 Provides a Link between Recombination Enzymes and Synaptonemal Complex Proteins (2000) (286)
- DNA rearrangements associated with a transposable element in yeast (1980) (276)
- Pch2 Links Chromatin Silencing to Meiotic Checkpoint Control (1999) (266)
- Zip2, a Meiosis-Specific Protein Required for the Initiation of Chromosome Synapsis (1998) (240)
- Meiosis in asynaptic yeast. (1990) (240)
- Cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S. cerevisiae (1984) (232)
- Imposition of Crossover Interference through the Nonrandom Distribution of Synapsis Initiation Complexes (2004) (221)
- Roles for two RecA homologs in promoting meiotic chromosome synapsis. (1995) (215)
- The Meiosis-Specific Hop2 Protein of S. cerevisiae Ensures Synapsis between Homologous Chromosomes (1998) (201)
- Meiosis-specific RNA splicing in yeast (1991) (196)
- Global analysis of the meiotic crossover landscape. (2008) (193)
- The budding yeast Msh4 protein functions in chromosome synapsis and the regulation of crossover distribution. (2001) (189)
- Meiotic Chromosome Synapsis-Promoting Proteins Antagonize the Anti-Crossover Activity of Sgs1 (2006) (177)
- Role for the silencing protein Dot1 in meiotic checkpoint control. (2000) (177)
- A unique pathway of double-strand break repair operates in tandemly repeated genes (1991) (176)
- A Synaptonemal Complex Protein Promotes Homology-Independent Centromere Coupling (2005) (175)
- A multipurpose transposon system for analyzing protein production, localization, and function in Saccharomyces cerevisiae. (1997) (173)
- Tam1, a telomere-associated meiotic protein, functions in chromosome synapsis and crossover interference. (1997) (172)
- Zip1-induced changes in synaptonemal complex structure and polycomplex assembly (1995) (168)
- Meiotic gene conversion and crossing over: Their relationship to each other and to chromosome synapsis and segregation (1990) (166)
- The origins of gene instability in yeast. (1980) (162)
- The Sgs1 Helicase Regulates Chromosome Synapsis and Meiotic Crossing Over (2003) (157)
- Sex and the single cell: meiosis in yeast. (1995) (147)
- The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2. (2006) (145)
- The importance of genetic recombination for fidelity of chromosome pairing in meiosis. (2003) (141)
- The Mnd1 Protein Forms a Complex with Hop2 To Promote Homologous Chromosome Pairing and Meiotic Double-Strand Break Repair (2002) (136)
- A meiosis-specific protein kinase homolog required for chromosome synapsis and recombination. (1991) (135)
- Organization of the Yeast Zip1 Protein within the Central Region of the Synaptonemal Complex (2000) (132)
- RED1: a yeast gene required for the segregation of chromosomes during the reductional division of meiosis. (1988) (131)
- MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis (1990) (128)
- Centromere-Proximal Crossovers Are Associated With Precocious Separation of Sister Chromatids During Meiosis in Saccharomyces cerevisiae (2006) (127)
- Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. (2006) (125)
- Telomere-mediated chromosome pairing during meiosis in budding yeast. (1998) (123)
- Meiotic chromosome morphology and behavior in zip1 mutants of Saccharomyces cerevisiae. (1998) (120)
- Transcription by RNA polymerase I stimulates mitotic recombination in Saccharomyces cerevisiae (1989) (114)
- Initiation of meiotic chromosome synapsis at centromeres in budding yeast. (2008) (114)
- Heteroduplex DNA formation and homolog pairing in yeast meiotic mutants. (1995) (113)
- The pachytene checkpoint prevents accumulation and phosphorylation of the meiosis-specific transcription factor Ndt80. (2000) (112)
- Saccharomyces cerevisiae Mer2, Mei4 and Rec114 Form a Complex Required for Meiotic Double-Strand Break Formation (2006) (110)
- Bdf1, a yeast chromosomal protein required for sporulation (1995) (106)
- Hed1 regulates Rad51-mediated recombination via a novel mechanism. (2008) (94)
- Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein. (1998) (89)
- The pachytene checkpoint in S. cerevisiae depends on Swe1-mediated phosphorylation of the cyclin-dependent kinase Cdc28. (1999) (89)
- Movement of yeast transposable elements by gene conversion. (1982) (87)
- Pachytene Exit Controlled by Reversal of Mek1-Dependent Phosphorylation (2000) (86)
- Chromsome synapsis and genetic recombination: their roles in meiotic chromsome segregation (1990) (85)
- The Budding Yeast Mei5 and Sae3 Proteins Act Together With Dmc1 During Meiotic Recombination (2004) (84)
- A Role for SUMO in Meiotic Chromosome Synapsis (2006) (81)
- Repression of meiotic crossing over by a centromere (CEN3) in Saccharomyces cerevisiae. (1986) (81)
- Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous. (1990) (81)
- The yeast MER2 gene is required for chromosome synapsis and the initiation of meiotic recombination. (1995) (81)
- Bacteriophage T7 morphogenesis: phage-related particles in cells infected with wild-type and mutant T7 phage. (1977) (76)
- Yeast mer1 mutants display reduced levels of meiotic recombination. (1989) (75)
- Transposable element sequences involved in the enhancement of yeast gene expression. (1985) (70)
- The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I (2009) (69)
- MEI4, a yeast gene required for meiotic recombination. (1989) (67)
- MEI4, a meiosis-specific yeast gene required for chromosome synapsis (1992) (65)
- A yeast acts in (Cis) to inhibit meiotic gene conversion of adjacent sequences (1988) (65)
- Fpr3 and Zip3 Ensure that Initiation of Meiotic Recombination Precedes Chromosome Synapsis in Budding Yeast (2009) (62)
- A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint. (2002) (61)
- Chromosome synapsis and genetic recombination: their roles in meiotic chromosome segregation. (1990) (59)
- Binding of a cell-type-specific RNA splicing factor to its target regulatory sequence (1995) (58)
- Mutations in U1 snRNA bypass the requirement for a cell type-specific RNA splicing factor (1993) (58)
- The yeast med1 mutant undergoes both meiotic homolog nondisjunction and precocious separation of sister chromatids. (1994) (54)
- [9] Spore enrichment (1991) (53)
- A Role for DNA Polymerase δ in Gene Conversion and Crossing Over During Meiosis in Saccharomyces cerevisiae (2004) (52)
- The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis. (1992) (51)
- Isolation and characterization of the SPT2 gene, a negative regulator of Ty-controlled yeast gene expression (1985) (51)
- The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. (1995) (50)
- Transposable elements (Ty) in yeast. (1981) (49)
- A yeast centromere acts in cis to inhibit meiotic gene conversion of adjacent sequences. (1988) (49)
- A chromosome containing HOT1 preferentially receives information during mitotic interchromosomal gene conversion. (1990) (46)
- Mitotic recombination in yeast. (1988) (42)
- Centromere-Like Regions in the Budding Yeast Genome (2013) (40)
- Bypass of a Meiotic Checkpoint by Overproduction of Meiotic Chromosomal Proteins (2000) (37)
- High-throughput methods for the large-scale analysis of gene function by transposon tagging. (2000) (35)
- Spore enrichment. (1991) (34)
- Intrachromosomal movement of genetically marked Saccharomyces cerevisiae transposons by gene conversion (1984) (34)
- A Novel Nonnull ZIP1 Allele Triggers Meiotic Arrest With Synapsed Chromosomes in Saccharomyces cerevisiae (2007) (32)
- High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity (2013) (32)
- Transposon mutagenesis for the analysis of protein production, function, and localization. (1999) (30)
- CHAPTER 7 – Transposable Elements in Yeast (1983) (28)
- Control of yeast gene expression by transposable elements: maximum expression requires a functional Ty activator sequence and a defective Ty promoter (1988) (24)
- The structure and maturation of intermediates in bacteriophage T7 DNA replication. (1978) (22)
- SSP2 and OSW1, Two Sporulation-Specific Genes Involved in Spore Morphogenesis in Saccharomyces cerevisiae (2007) (18)
- Pathways of recombination of bacteriophage T7 DNA in vitro. (1979) (18)
- Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast (1989) (17)
- Unequal crossing-over between yeast transposable elements (1983) (17)
- Cdc14 Early Anaphase Release, FEAR, Is Limited to the Nucleus and Dispensable for Efficient Mitotic Exit (2015) (17)
- Splicing of the Meiosis-Specific HOP2Transcript Utilizes a Unique 5′ Splice Site (1999) (15)
- 10 Transposon Tagging I: A Novel System for Monitoring Protein Production, Function and Localization (1998) (6)
- Multiple Pairwise Analysis of Non-homologous Centromere Coupling Reveals Preferential Chromosome Size-Dependent Interactions and a Role for Bouquet Formation in Establishing the Interaction Pattern (2016) (4)
- Rad 51-mediated recombination via a novel mechanism (2008) (4)
- Isolation and characterization of yeast mutants defective in meiotic chromosome segregation. (1989) (4)
- Control of yeast gene expression by transposable elements. (1986) (3)
- Construction of yeast strains containing genetically marked transposons. (1982) (2)
- utation of a Meiosis-Specific MutS creases Crossing Over Not Mismatch Correction (1994) (1)
- Large-scale analysis of gene expression, protein localization, and gene dlsrupuon in Saccharomyces cerevisiae (2007) (1)
- Control ofYeastGeneExpression byTransposable Elements: MaximumExpression Requires a Functional TyActivator Sequence anda Defective TyPromoter (1988) (0)
- Correction: High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity (2013) (0)
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