Shoichi Kusumoto

Shoichi Kusumoto's AcademicInfluence.com Rankings

Shoichi Kusumoto

Biology

#11512

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#14913

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Microbiology

#655

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#724

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Immunology

#738

World Rank

#760

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Biochemistry

#1907

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#2048

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Biology

Shoichi Kusumoto's Degrees

PhD Microbiology University of Tokyo
Masters Microbiology University of Tokyo
Bachelors Biology University of Tokyo

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Shoichi Kusumoto's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2 (2003) (1697)
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid (2003) (1303)
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. (2000) (786)
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification. (1996) (488)
Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway. (2004) (408)
Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response (2006) (391)
Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 (2003) (330)
IL-1 induction-capacity of defined lipopolysaccharide partial structures. (1989) (258)
Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. (2001) (254)
Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. (2004) (252)
Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase* (2003) (234)
Muramyldipeptide and diaminopimelic acid‐containing desmuramylpeptides in combination with chemically synthesized Toll‐like receptor agonists synergistically induced production of interleukin‐8 in a NOD2‐ and NOD1‐dependent manner, respectively, in human monocytic cells in culture (2004) (230)
The chemical structure of bacterial endotoxin in relation to bioactivity. (1993) (228)
TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. (2002) (215)
Aggregates Are the Biologically Active Units of Endotoxin* (2004) (212)
Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures (1994) (189)
Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity. (2000) (182)
The charge of endotoxin molecules influences their conformation and IL-6-inducing capacity. (1998) (176)
Total synthesis of escherichia coli lipid A (1985) (169)
Toll-like Receptors, NOD1, and NOD2 in Oral Epithelial Cells (2006) (164)
Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes (1997) (159)
Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses. (2004) (155)
Total Synthesis of Escherichia coli Lipid A, the Endotoxically Active Principle of Cell-Surface Lipopolysaccharide (1987) (152)
Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity. (2005) (145)
A Dominant Role of Toll-Like Receptor 4 in the Signaling of Apoptosis in Bacteria-Faced Macrophages 1 (2003) (140)
Chemical Synthesis of N-Acetylmuramyl Peptides with Partial Structures of Bacterial Cell Wall and Their Analogs in Relation to Immunoadjuvant Activities (1976) (135)
Chemically synthesized pathogen‐associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll‐like receptors, NOD1 and NOD2 in human oral epithelial cells (2005) (130)
Lipopolysaccharides (LPS) of Oral Black-Pigmented Bacteria Induce Tumor Necrosis Factor Production by LPS-Refractory C3H/HeJ Macrophages in a Way Different from That of Salmonella LPS (1999) (122)
Endotoxin and lipid A stimulate proliferation of human T cells in the presence of autologous monocytes. (1994) (112)
Chemical structure of Escherichia coli lipid A (1985) (111)
Induction of human interleukin 1 by bacterial and synthetic lipid A (1986) (111)
Chemical structure of E. Coli Lipid A: Linkage site of acyl groups in the disaccharide backbone (1983) (110)
Chemical synthesis of phosphorylated tetraacyl disaccharide corresponding to a biosynthetic precursor of lipid A (1984) (104)
Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate (1984) (100)
Dendritic Cell Maturation Induced by Muramyl Dipeptide (MDP) Derivatives: Monoacylated MDP Confers TLR2/TLR4 Activation1 (2005) (100)
Conformational studies of synthetic lipid A analogues and partial structures by infrared spectroscopy. (1997) (98)
Vaccination of experimental monkeys against Plasmodium falciparum: a possible safe adjuvant. (1978) (97)
Stimulation of the reticuloendothelial system of mice by muramyl dipeptide (1979) (92)
Lipopolysaccharide and peptidoglycan: CD14-dependent bacterial inducers of inflammation. (1998) (89)
Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A (1992) (88)
Total Synthesis of Lipid A, Active Principle of Bacterial Endotoxin (1984) (87)
Lipopolysaccharides: structural principles and biologic activities. (1984) (86)
Immobilization and clustering of structurally defined oligosaccharides for sugar chips: an improved method for surface plasmon resonance analysis of protein-carbohydrate interactions. (2006) (84)
First Total Synthesis of the Re-Type Lipopolysaccharide. (2001) (83)
Plasticity of Escherichia coli porin channels. Dependence of their conductance on strain and lipid environment. (1991) (82)
Differential Activation of Human TLR4 by Escherichia coli and Shigella flexneri 2a Lipopolysaccharide: Combined Effects of Lipid A Acylation State and TLR4 Polymorphisms on Signaling1 (2008) (82)
Heparin modulates integrin function in human platelets. (2001) (79)
Structure-activity relationship of lipid A: comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions. (1986) (77)
The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment (1987) (76)
Induction of tumor necrosis factor-alpha release by lipopolysaccharide and defined lipopolysaccharide partial structures. (1989) (75)
Immunobiological activities of chemically defined lipid A from Helicobacter pylori LPS in comparison with Porphyromonas gingivalis lipid A and Escherichia coli-type synthetic lipid A (compound 506). (1997) (74)
Chemical Synthesis of a Biosynthetic Precursor of Lipid A with a Phosphorylated Tetraacyl Disaccharide Structure (1987) (73)
Stimulation of nonspecific resistance to infection induced by 6-O-acyl muramyl dipeptide analogs in mice (1981) (67)
Binding of lipopolysaccharide (LPS) to an 80-kilodalton membrane protein of human cells is mediated by soluble CD14 and LPS-binding protein (1995) (67)
Synthesis of peptidoglycan fragments and evaluation of their biological activity. (2006) (67)
Macrophage activation by bacterial cell walls and related synthetic compounds (1979) (66)
Biological activity of synthetic heptaacyl lipid A representing a component of Salmonella minnesota R595 lipid A. (1986) (66)
Molecular and structural requirements of a lipoteichoic acid from Enterococcus hirae ATCC 9790 for cytokine-inducing, antitumor, and antigenic activities (1995) (66)
Chemical structure of lipid A from Helicobacter pylori strain 206-1 lipopolysaccharide. (1997) (64)
Structure of de-o-acylated lipopolysaccharide from the escherichia coli re mutant strain F 515 (1985) (64)
Endotoxic and immunobiological activities of a chemically synthesized lipid A of Helicobacter pylori strain 206-1. (2003) (64)
Intracellular serine-protease zymogen, factor C, from horseshoe crab hemocytes. Its activation by synthetic lipid A analogues and acidic phospholipids. (1988) (64)
An Efficient Procedure for Solid-Phase Synthesis of Phosphopeptides by the Fmoc Strategy (1994) (61)
DIVERGENT SYNTHESIS AND BIOLOGICAL ACTIVITIES OF LIPID A ANALOGUES OF SHORTER ACYL CHAINS (1998) (60)
Synthesis of long chain fatty acid esters of N-acetylmuramyl-L-alanyl-D-isoglutamine in relation to antitumor activity (1979) (60)
A stereoselective glycosidation using thioglycosides, activation by combination of N-bromosuccinimide and strong acid salts (1995) (58)
Regioselective Reductive Opening of 4,6-O-Benzylidene Acetals of Glucose or Glucosamine Derivatives by BH3⋅Me2NH - BF3⋅OEt2 (1996) (58)
A Synthetic Peptidoglycan Fragment as a Competitive Inhibitor of the Melanization Cascade* (2006) (58)
Glycosphingolipids from Sphingomonas paucimobilis induce monokine production in human mononuclear cells (1995) (57)
Meso-Diaminopimelic Acid and Meso-Lanthionine, Amino Acids Specific to Bacterial Peptidoglycans, Activate Human Epithelial Cells through NOD11 (2006) (57)
Arthritis-inducing ability of a synthetic adjuvant, N-acetylmuramyl peptides, and bacterial disaccharide peptides related to different oil vehicles and their composition (1980) (57)
Toll-like Receptors of the Ascidian Ciona intestinalis (2009) (56)
Mitogenic Effects of Bacterial Cell Walls, Their Fragments, and Related Synthetic Compounds on Thymocytes and Splenocytes of Guinea Pigs (1979) (54)
Synthesis of 6-O-Acyl Derivatives of Immunoadjuvant Active N-Acetylmuramyl-L-alanyl-D-isoglutamine (1978) (53)
Cytokine-inducing glycolipids in the lipoteichoic acid fraction from Enterococcus hirae ATCC 9790. (1995) (53)
Cell activation by monosaccharide lipid A analogues utilizing Toll‐like receptor 4 (2003) (52)
Stimulating effect of MDP and its adjuvant-active analogues on guinea pig fibroblasts for the production of thymocyte-activating factor (1983) (51)
Structural requirements of lipid A species in activation of clotting enzymes from the horseshoe crab, and the human complement cascade. (1988) (51)
Minimum structural requirements for encephalitogen and for adjuvant in the induction of experimental allergic encephalomyelitis. (1978) (51)
CD55/decay accelerating factor is part of the lipopolysaccharide‐induced receptor complex (2003) (51)
Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds (1978) (50)
Evidence of Immunostimulating Lipoprotein Existing in the Natural Lipoteichoic Acid Fraction (2007) (49)
Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells (1991) (49)
Modulation of endotoxin-induced monokine release in human monocytes by lipid A partial structures that inhibit binding of 125I-lipopolysaccharide (1992) (49)
Correlation of stereochemically specific structure in muramyl dipeptide between macrophage activation and adjuvant activity. (1977) (49)
A Divergent Synthesis of Lipid A and Its Chemically Stable Unnatural Analogues (1999) (49)
The significance of the hydrophilic backbone and the hydrophobic fatty acid regions of lipid A for macrophage binding and cytokine induction. (1994) (48)
Determination of the epitope specificity of monoclonal antibodies against the inner core region of bacterial lipopolysaccharides by use of 3-deoxy-D-manno-octulosonate-containing synthetic antigens. (1989) (47)
Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling (2004) (47)
Modulation of lipopolysaccharide-induced production of tumor necrosis factor, interleukin 1, and interleukin 6 by synthetic precursor Ia of lipid A. (1992) (47)
Structural basis for endotoxic and antagonistic activities: investigation with novel synthetic lipid A analogs (2003) (46)
Preparation of novel pyranosyl fluorides of 3-deoxy-D--2-octulosonic acid (KDO) feasible for synthesis of KDO α-glycosides (1987) (46)
A CONVENIENT PREPARATIVE METHOD OF CARBOHYDRATE PHOSPHATES WITH BUTYLLITHIUM AND PHOSPHOROCHLORIDATE (1982) (46)
Immunopharmacological activities of a synthetic counterpart of a biosynthetic lipid A precursor molecule and of its analogs (1985) (45)
Chemical structure and biological activity of a lipid A component from Helicobacter pylori strain 206 (2001) (44)
A Novel Method for Stereoselective Glycosidation with Thioglycosides: Promotion by Hypervalent Iodine Reagents Prepared from PhIO and Various Acids? (1996) (43)
Chemical synthesis of 1-dephospho derivative of lipid A (1985) (43)
Lipopolysaccharide-binding protein-mediated interaction of lipid A from different origin with phospholipid membranes (2000) (42)
Requirement of a properly acylated beta(1-6)-D-glucosamine disaccharide bisphosphate structure for efficient manifestation of full endotoxic and associated bioactivities of lipid A (1987) (41)
Immunobiological activities of synthetic lipid A analogs and related compounds as compared with those of bacterial lipopolysaccharide, re-glycolipid, lipid A, and muramyl dipeptide (1983) (41)
ChemInform Abstract: Synthetic Study of Peptidoglycan Partial Structures. Synthesis of Tetrasaccharide and Octasaccharide Fragments. (2001) (41)
MPIase is a glycolipozyme essential for membrane protein integration (2012) (41)
Macrophage-stimulating effect of a synthetic muramyl dipeptide and its adjuvant-active and -inactive analogs for the production of T-cell activating monokines. (1981) (41)
Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures (1992) (40)
Interaction of lipopolysaccharide and phospholipid in mixed membranes: solid-state 31P-NMR spectroscopic and microscopic investigations. (2008) (40)
Small-scale solid-phase O-glycopeptide synthesis of linear and cyclized hexapeptides from blood-clotting factor IX containing O-(α-D-Xyl-1→3-α-D-Xyl-1→3-β-D-Glc)-L-ser (1993) (40)
Immunogenicity and antigenicity of synthetic Escherichia coli lipid A (1986) (38)
Synthetic Study of Lipoteichoic Acid of Gram Positive Bacteria. II. Synthesis of the Proposed Fundamental Structure of Enterococcus hirae Lipoteichoic Acid (1994) (38)
A novel complete reconstitution system for membrane integration of the simplest membrane protein. (2010) (36)
A practical synthesis of the phytosiderophore 2'-deoxymugineic acid: a key to the mechanistic study of iron acquisition by graminaceous plants. (2007) (35)
Synthetic Study on Lipoteichoic Acid of Gram Positive Bacteria. I. Synthesis of Proposed Fundamental Structure of Streptococcus pyogenes Lipoteichoic Acid (1992) (35)
Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies (2010) (35)
Solid‐Phase Synthesis of a Phytoalexin Elicitor Pentasaccharide Using a 4‐Azido‐3‐chlorobenzyl Group as the Key for Temporary Protection and Catch‐and‐Release Purification (2003) (35)
On the active principles of the spurge family (Euphorbiaceae) (1984) (35)
Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: adaptability to various vehicles and pyrogenicity (1986) (34)
Structural specificity of synthetic peptide adjuvant for induction of experimental allergic encephalomyelitis. (1978) (34)
Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures (2007) (34)
Synthetic study of phosphopeptides related to heat shock protein HSP27. (1997) (34)
4-Nitrobenzyl group for protection of hydroxyl functions (1990) (34)
Mitogenic activities of synthetic lipid A analogs and suppression of mitogenicity of lipid A (1984) (33)
On the active principles of the spurge family (Euphorbiaceae) (1985) (33)
Synthetic low-toxicity muramyl dipeptide and monophosphoryl lipid A replace Freund complete adjuvant in inducing growth-inhibitory antibodies to the Plasmodium falciparum major merozoite surface protein, gp195 (1991) (32)
Acidic, Selective Monoacylation of vic-Diols. (1996) (32)
Stereoselective glycosylation using the long-range effect of a [2-(4-phenylbenzyl)oxycarbonyl]benzoyl group (2005) (32)
Mild but Efficient Methods for Stereoselective Glycosylation with Thioglycosides: Activation by [N-Phenylselenophthalimide-Mg(ClO4)2] and [PhIO-Mg(ClO4)2] (1998) (32)
Structural feature of the major but not cytokine-inducing molecular species of lipoteichoic acid. (1997) (32)
Chemical synthesis of phosphorylated fundamental structure of lipid a (1981) (31)
New Efficient Synthesis of a Biosynthetic Precursor of Lipid A (1997) (31)
Synthesis of lipid A and its analogues for investigation of the structural basis for their bioactivity. (2005) (31)
Detection of UDP-D-Xylose:α-D-Xyloside α→3Xylosyltransferase Activity in Human Hepatoma Cell Line HepG2 (1996) (31)
Chemical structure of lipid A (1985) (31)
Immunoadjuvant activities of synthetic 6-O-acyl-N-acetylmuramyl-L-alanyl-D-isoglutamine with special reference to the effect of its administration with liposomes. (1977) (31)
Synthesis and antitumor activity of lipid A analogs having a phosphonooxyethyl group with alpha- or beta-configuration at position 1. (1990) (31)
Synthesis of Helicobacter pylori lipid A and its analogue using p-(trifluoromethyl)benzyl protecting group (2000) (30)
Synthetic approach to bacterial lipopolysaccharide, preparation of trisaccharide part structures containing KDO and 1-dephospho lipid A (1988) (30)
Iodosobenzene-triflic anhydride as an efficient promoter for glycosidation reaction using thioglycosides as donors (1992) (30)
Lipophilic derivative of muramyl dipeptide is more active than muramyl dipeptide in priming macrophages to release superoxide anion (1980) (29)
Physicochemical characterization of carboxymethyl lipid A derivatives in relation to biological activity (2005) (29)
Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1. (2008) (29)
Total synthesis of antibiotic streptothricin F (1982) (29)
Endotoxic properties of synthetic pentaacyl lipid A precursor Ib and a structural isomer. (1987) (29)
Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies. (1997) (28)
New efficient route for solid-phase synthesis of benzimidazole derivatives. (2002) (28)
On a practical synthesis of β-hydroxy fatty acid derivatives (1995) (28)
Interferon-inducing, pyrogenic and proclotting enzyme of horseshoe crab activation activities of chemically synthesized lipid A analogues. (1983) (28)
Chemical syntheses of lipid X and lipid Y, acyl glucosamine 1-phosphates isolated from escherichia coli mutants (1985) (28)
Synthesis of 6-O-Mycoloyl-Nacetylmuramyl-L-alanyl-D-isoglutamine with Antitumor Activity (1978) (28)
Synthetic Salmonella-type lipid A antigen with high serological specificity (1986) (28)
Comparative X-ray and Fourier-transform-infrared investigations of conformational properties of bacterial and synthetic lipid A of Escherichia coli and Salmonella minnesota as well as partial structures and analogues thereof. (1989) (28)
Synthesis of lyposaccharide corresponding to fundamental structure of Salmonella-type lipid A (1980) (27)
Biological activity of chemically synthesized analogues of lipid A. Demonstration of adjuvant effect in hapten-sensitized liposomal system. (2005) (27)
Structural requirements of endotoxic lipopolysaccharides and bacterial cell walls in induction of interleukin-1. (1988) (27)
Synthetic approach to lipid A: Preparation of phosphorylated disaccharides containing (R)-3-hydroxyacyl and (R)-3-acyloxyacyl groups (1983) (27)
Stimulation of migration of human monocytes by bacterial cell walls and muramyl peptides (1982) (27)
Synthesis of new serine-linked oligosaccharides in blood-clotting factors VII and IX and protein Z. The syntheses of O-α-D-Xylopyranosyl-(1→3)-D-glucopyranose, O-α-D-Xylopyranosyl-(1→3)-O-α-D-xylopyranosyl-(1→3)-D-glucopyranose, and their conjugates with serine (1992) (27)
Activation of the Human Complement Cascade by Bacterial Cell Walls, Peptidoglycans, Water‐Soluble Peptidoglycan Components, and Synthetic Muramylpeptides—Studies on Active Components and Structural Requirements (1987) (27)
Synthesis of endotoxic principle of bacterial lipopolysaccharide and its recognition by the innate immune systems of hosts. (2006) (27)
A typical bacterial ornithine-containing lipid Nalpha-(D)-[3-(hexadecanoyloxy)hexadecanoyl]-ornithine is a strong stimulant for macrophages and a useful adjuvant. (1999) (26)
Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation (1999) (26)
Laser desorption mass spectrometry of synthetic lipid A-like compounds. (1984) (26)
Inhibition of LPS binding on human monocytes by phosphonooxyethyl analogs of lipid A (1994) (26)
Mitogenic activity of adjuvant-active N-acetylmuramyl-L-alanyl-D-isoglutamine and its analogues. (1977) (25)
A Novel Oxidatively Removable Linker and Its Application to α-Selective Solid-Phase Oligosaccharide Snythesis on a Macroporous Polystyrene Support (1999) (25)
Structural features that influence the ability of lipid A and its analogs to abolish expression of suppressor T cell activity (1992) (25)
Total chemical structure of streptothricin. (1982) (25)
Macrophage activation in response to S-form lipopolysaccharides (LPS) separated by centrifugal partition chromatography from wild-type LPS: effects of the O-polysaccharide portion of LPS. (1995) (25)
Suppressive effect of lipid A partial structures on lipopolysaccharide or lipid A-induced release of interleukin 1 by human monocytes. (1990) (25)
Synthesis of [3H]-Labeled Bioactive Lipid A Analogs and Their Use for Detection of Lipid A-Binding Proteins on Murine Macrophages. (2001) (25)
Chemical synthesis of cyclodextrins by using intramolecular glycosylation. (2002) (24)
Chemical synthesis of lipid for the elucidation of structure-activity relationships (1983) (24)
Simple formylacetal (CH2) as a novel linker for saccharide synthesis on soluble-polymer support (2004) (24)
In vitro antigenic reactivity of synthetic lipid A analogues as determined by monoclonal and conventional antibodies. (1985) (24)
Higher Immunoadjuvant Activities of N‐Acetyl‐β‐D‐glucosaminyl‐(1–4)‐N‐acetylmuramyl‐L‐alanyl‐D‐isoglutamine in Comparison with N‐Acetylmuramyl‐L‐alanyl‐D‐isoglutamine (1979) (24)
Contractile effects of bacterial cell walls, their enzymatic digests, and muramyl dipeptides on ileal strips from guinea pigs (1982) (24)
Synthesis of lipid A monosaccharide analogues containing acidic amino acid: exploring the structural basis for the endotoxic and antagonistic activities. (2006) (24)
Mitogenic and polyclonal B cell activation activities of synthetic lipid A analogues (1984) (24)
Enzyme flexibility: a new concept in recognition of hydrophobic substrates. (1997) (24)
Cytokine-inducing macromolecular glycolipids from Enterococcus hirae: improved method for separation and analysis of its effects on cellular activation. (2000) (23)
TMSCl as a Mild and Effective Source of Acidic Catalysis in Fischer Glycosidation and Use of Propargyl Glycoside for Anomeric Protection (2002) (23)
NMR conformational analysis of biosynthetic precursor-type lipid A: monomolecular state and supramolecular assembly. (2004) (23)
Chemoenzymatic synthesis of Gal(β1-3)Gal(β1-4)Xyl(β)-l-Ser and Gal(β1-3)Gal(β1-4)Xyl(β)-MU by the use of β-d-galactosidase (1996) (23)
Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn's disease. (2002) (23)
p-Nitrophenyl group for anomeric protection of oligosaccharides, selective oxidative cleavage via p-acetamidophenyl glycosides (1996) (22)
Polyclonal B Cell Activation by Cell Wall Preparations of Gram‐Positive Bacteria (1980) (22)
Inhibition of endotoxin or lipid A-induced tumor necrosis factor production by synthetic lipid A partial structures in human peripheral blood mononuclear cells. (1992) (22)
Oligosaccharide Synthesis by Affinity Separation Based on Molecular Recognition between Podand Ether and Ammonium Ion (2005) (22)
Structural characterization of heparin's binding domain for human platelets. (1993) (22)
Synthesis and biological activity of oligomer-model compounds containing units of a key platelet-binding disaccharide of heparin (1999) (21)
Synthesis of an analog of biosynthetic precursor Ia of lipid A by an improved method: a novel antagonist containing four (S)-3-hydroxy fatty acids (1995) (21)
Chemical Synthesis and Biological Activities of Two Disaccharide Dipeptides Corresponding to the Repeating Units of Bacterial Peptidoglycan (1986) (21)
Adjuvant and antitumour activities of synthetic lipid A analogues. (1986) (21)
Possible Chemotaxis of Human Monocytes by N-Acetylmuramyl-l-Alanyl-d-Isoglutamine (1983) (20)
Specific transporter for iron(III): Phytosiderophore complex involved in iron uptake by barley roots (2008) (20)
Liberation of serotonin from rabbit blood platelets by bacterial cell walls and related compounds (1982) (20)
Somnogenic activities of synthetic lipid A (1989) (20)
Synthesis of heparin partial structures and their binding activities to platelets. (1999) (20)
Further study of biological activities of chemically synthesized analogues of lipid A in artificial membrane vesicles. (1984) (20)
BENZYL TRITYL ETHER AND DDQ AS NEW TRITYLATING REAGENTS (1998) (19)
Enhancement of humoral immune responses against viral vaccines by a non-pyrogenic 6-O-acylmuramyldipeptide and synthetic low toxicity analogues of lipid A. (1989) (19)
Synthesis of Rubrivivax gelatinosus Lipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities (2008) (19)
Enzymatic Preparation of (S)-3-Hydroxytetradecanoic Acid and Synthesis of Unnatural Analogues of Lipid A Containing the (S)-Acid (1997) (19)
Chemical synthesis of bisdephospho lipid a of Salmonella endotoxin. (1980) (19)
Structural characteristics of peptidoglycan fragments required to prime mice for induction of anaphylactoid reactions by lipopolysaccharides (1996) (18)
Lipid A, the immunostimulatory principle of lipopolysaccharides? (1990) (18)
Synthesis of β(1–4)-Linked Disaccharides of N-Acetylglucosamine and N-Acetylmuramic Acid by Their Direct Condensation (1986) (18)
3-Nitro-2-pyridyl glycoside as donor for chemical glycosylation and its application to chemoenzymatic synthesis of oligosaccharide (1999) (18)
Synthesis of oligomeric assemblies of a platelet-binding key disaccharide in heparin and their biological activities (2001) (18)
Synthesis and biological activity of a model disaccharide containing a key unit in heparin for binding to platelets (1996) (18)
Biological activities of lipopolysaccharides of Proteus spp. and their interactions with polymyxin B and an 18-kDa cationic antimicrobial protein (CAP18)-derived peptide. (2000) (18)
Synthesis of 13C-Labeled Biosynthetic Precursor of Lipid A and Its Analogue with Shorter Acyl Chains (1999) (17)
New methodology for high throughput solution-phase synthesis: affinity purification by using crown ether and ammonium ion interaction (1999) (17)
What we know and don't know about the chemical and physical structure of lipopolysaccharide in relation to biological activity. (1998) (17)
Adjuvant activity of synthetic cell-wall peptidoglycan subunits on monoazobenzenearsonate-N-acetyl-L-tyrosine and bacterial alpha-amylase in guinea pigs. (1976) (17)
4-Pivaloylaminobenzyl ether, a new temporary protection for hydroxyl functions (1991) (17)
Adjuvant Activities in Production of Reaginic Antibody by Bacterial Cell Wall Peptidoglycan or Synthetic N-Acetylmuramyl Dipeptides in Mice (1979) (17)
The Internalization Time Course of a Given Lipopolysaccharide Chemotype Does Not Correspond to Its Activation Kinetics in Monocytes (1999) (17)
Partial degradation and biological activities of an antitumor polysaccharide from rice bran. (1991) (17)
Selective Chemical Cleavage of Asparagine Peptides (1968) (17)
Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: dose-response and local reactions observed with selected compounds (1986) (17)
A FACILE METHOD FOR PREPARATION OF THE OPTICALLY PURE 3-HYDROXYTETRADECANOIC ACID BY AN APPLICATION OF ASYMMETRICALLY MODIFIED NICKEL CATALYST (1980) (17)
Macrophages are stimulated by muramyl dipeptide to induce polymorphonuclear leukocyte accumulation in the peritoneal cavities of guinea pigs (1990) (17)
Structural elucidation of polysaccharide part of glycoconjugate from Treponema medium ATCC 700293. (2003) (16)
Synthesis of Streptolidine (Roseonine, Geamine) (1974) (16)
One-pot preparation and activation of glycosyl trichloroacetimidates: operationally simple glycosylation induced by combined use of solid-supported, reactivity-opposing reagents (2004) (16)
4-Azidobutyryl Group for Temporary Protection of Hydroxyl Functions (1986) (16)
Synthesis and Biological Activities of Analogs of a Lipid A Biosynthetic Precursor : 1-O-Phosphono-oxyethyl-4'-O-phosphono-disaccharides with (R)-3-Hydroxytetradecanoyl or Tetradecanoyl Groups at Positions 2, 3, 2' and 3' (1991) (16)
Propargyloxycarbonyl and propargyl groups for novel protection of amino, hydroxy, and carboxy functions (1999) (16)
Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system (2011) (15)
Synthesis of 6-o-mycoloyl-n-acetylmuramyl-l-alanyl- D-isoglutamine with immunoadjuvant activity (1976) (15)
Total Synthesis of Escherichia coli Lipid A, the Endotoxically Active Principle of Cell-Surface Lipopolysaccharide. (1987) (15)
Constituents of leaf oil from Japanese pepper. (1968) (15)
Application of 4-azidobenzyl group to protection of hydroxyl functions (1991) (15)
New Efficient Route for Synthesis of Lipid A by using Affinity Separation (2001) (14)
CHEMICAL SYNTHESIS AND BIOLOGICAL ACTIVITY OF LIPID A ANALOGS (1985) (14)
A New Catch-and-Release Purification Method Using a 4-Azido-3-chlorobenzyl Group (2001) (14)
IEIIS Meeting minireview: Chemical synthesis of peptidoglycan fragments for elucidation of the immunostimulating mechanism (2007) (14)
Immunomodulating and Related Biological Activities of Bacterial Cell Walls and Their Components, Enzymatically Prepared or Synthesized (1981) (14)
New synthesis and conformational analysis of lipid A: biological activity and supramolecular assembly (1999) (14)
Enzymatic Synthesis of 4-Methylumbelliferyl Glycosides of Trisaccharide and Core Tetrasaccharide, Gal(β1-3)Gal(β1-4)Xyl and GlcA(β1-3)Gal(β1-3)Gal(β1-4)Xyl, Corresponding to the Linkage Region of Proteoglycans (1997) (14)
Characterization of monoclonal antibodies recognizing three distinct, phosphorylated carbohydrate epitopes in the lipopolysaccharide of the deep rough mutant I‐69 Rd−/b+ of Haemophilus influenzae (1997) (14)
Interleukin 1 and tumor necrosis factor: studies on the induction by lipopolysaccharide partial structures. (1989) (14)
Synthesis and biological activities of lipid A analogs possessing β-glycosidic linkage at 1-position (2003) (14)
An efficient procedure for synthesis of phosphopeptides through the benzyl phosphate-protection by the Boc mode solid-phase method (1993) (14)
Structural principles of lipopolysaccharides and biological properties of synthetic partial structures (1983) (13)
Chemical synthesis of 1-dephospho derivative of escherichia coli re lipopolysaccharide (1988) (13)
An efficient method for the assembly of sulfated oligosaccharides using reductive amination (2001) (13)
2JC,H index: a nondestructive NMR method for differentiation of aldohexopyranosyl residues. (2005) (13)
Recent developments in the organic synthesis of lipid A in relation to biologic activities. (1984) (13)
Synthesis and immunoreactivity of poly(acrylamide) copolymers containing C-3- and C-7-modified, carboxyl-reduced, 4-O- and 5-O-phosphorylated K (1993) (13)
Functional fluorescence labeling of carbohydrates and its use for preparation of neoglycoconjugates (1994) (13)
Synthesis and purification by HPLC of des-O-acyl partial structures of Escherichia coli Re lipopolysaccharide (1994) (13)
Novel Dehydrative Glycosylation by Using Acid Anhydride and TMSClO4 (1999) (12)
Synthesis of allyl 3-deoxy-D-manno-2-octulopyranosidic acid 4- and 5-phosphates (1991) (12)
Synthesis and bioactivity of a fluorescence-labeled lipid A analogue (1999) (12)
Novel Molecular Clamp Method for Anomeric Stereocontrol of Glycosylation (1999) (12)
A novel cytokine-inducing glycolipid isolated from the lipoteichoic acid fraction of Enterococcus hirae ATCC 9790: A fundamental structure of the hydrophilic part (1999) (12)
Diterpene esters from ‘Euphorbium’ and their irritant and cocarcinogenic activity (1974) (12)
Synthesis based on affinity separation (SAS): Separation of products having barbituric acid tag from untagged compounds by using hydrogen bond interaction (2001) (12)
Reactivity switching on solid support: solid-phase synthesis of tertiary amines by reduction of tertiary amides with LiAlH4 (2002) (11)
Synthesis of Lipopolysaccharide, Peptidoglycan, and Lipoteichoic Acid Fragments (2007) (11)
The synthesis and in vitro and in vivo stability of 5-fluorouracil prodrugs which possess serum albumin binding potency. (1993) (11)
Solid-phase synthesis of indol-2-ones by microwave-assisted radical cyclization (2004) (11)
Synthesis of N-acetyl-β-D-glucosaminyl-(1-4)-N-acetylmuramyl- L -alanyl-D-isoglutamine☆ (1978) (11)
A new method for the determination of optical purity of synthetic peptides (1981) (11)
Design and Synthesis of Peptides Passing through the Blood-Brain Barrier (1998) (11)
Synthesis and biological activity of phosphoglycolipids from Thermus thermophilus. (2013) (11)
Granuloma formation by muramyl dipeptide associated with branched fatty acids, a structure probably essential for tubercle formation by Mycobacterium tuberculosis (1985) (11)
4-AZIDO-3-CHLOROBENZYL ETHER, NEW PROTECTION FOR HYDROXY FUNCTIONS (1997) (11)
Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs (1987) (11)
The Structure and the Stereochemistry of Solidagonic Acid (1969) (10)
Chemical Synthesis of Lipid A (1993) (10)
Structure and synthesis of lipid A. (2010) (10)
SYNTHESIS OF 6-O-MYCOLOYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE WITH ANTITUMOR ACTIVITY (1979) (10)
Synthesis and bioactivity of fluorescence- and biotin-labeled lipid A analogues for investigation of recognition mechanism in innate immunity (2006) (10)
Mitogenic effects of bacterial cell walls and their components on murine splenocytes. (1980) (10)
Participation of CD14 in the Phagocytosis of Smooth‐Type Salmonella typhimurium by the Macrophage‐Like Cell Line, J774.1 (1997) (10)
Synthetic route for 14C-labeling of a bioactive lipid a analogue (1995) (9)
Synthesis and biological function of bacterial endotoxin (1989) (9)
Separation of wild-type lipopolysaccharides by centrifugal partition chromatography: isolation of smooth form species (1996) (9)
Chemical Synthesis of Peptidoglycan Fragments for Elucidation of the Immunostimulating Mechanism (2008) (9)
Mugineic acid derivatives as molecular probes for the mechanistic elucidation of iron acquisition in barley. (2010) (8)
Selective Chemical Cleavage of Threonine Peptides (1968) (8)
A NEW METHOD FOR DETERMINATION OF INTACT OPTICAL PURITY OF PEPTIDES BY USE OF MASS FRAGMENTOGRAPHY (1981) (8)
The antibody reactivity of monoclonal lipid A antibodies is influenced by the acylation pattern of lipid A and the assay system employed. (1993) (8)
Structural elucidation of a capsular polysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn's disease. (2001) (8)
Synthesis of N-acetylmuramyl-L- [U−14C]alanyl-D-isoglutamine (1977) (8)
Chemical synthesis of bacterial lipid A (2010) (8)
Syntheses of Several Muramyl Peptides in Relation to Chemical Structures of Less Immunoadjuvant Bacterial Cell Walls (1979) (7)
Detection of UDP-D-xylose: alpha-D-xyloside alpha 1-->3xylosyltransferase activity in human hepatoma cell line HepG2. (1996) (7)
Immunological Activity of Synthetic Cell-Wall Peptidoglycan Subunits (1976) (7)
Biological activity of lipid A partial structures. (1994) (7)
SYNTHESIS OF Ng-STREPTOLIDYL GULOSAMINIDE — A NEW EVIDENCE FOR THE PROPOSED STRUCTURE OF ANTIBIOTIC STREPTOTHRICIN (1981) (7)
Conformational Study of a Tetraacyl Biosynthetic Precursor of Lipid A by NMR (2001) (7)
Preparation of Phosphoamino Acid Derivatives with Acid Stable O-Phosphono-Protection for the Boc-Mode Solid-Phase Synthesis of Phosphopeptides. (1995) (6)
Structural Characterization of Neutral and Acidic Glycolipids from Thermus thermophilus HB8 (2012) (6)
S-form lipopolysaccharide (LPS), but not lipid A or R-chemo-type LPS, induces interleukin-6 production in vitamin D3-differentiated THP-1 cells. (1999) (6)
Structural Requirement of Synthetic N‐Acetylmuramyl Dipeptides for Induction of Experimental Allergic Encephalomyelitis in the Rat (1980) (6)
Adjuvant activities in production of reaginic antibody in mice of bacterial cell wall peptidoglycans or peptidoglycan subunits and of synthetic N-acetylmuramyl dipeptides. (1977) (6)
An Efficient Procedure for Solid-Phase Synthesis of Phosphopeptides by the Fmoc Strategy. (1994) (6)
Characterization of monoclonal lipid A antibodies with synthetic lipid A analogues (1988) (6)
Novel oxidatively removable protecting groups and linkers for solid-phase synthesis of oligosaccharides (2005) (6)
Chemical Synthesis of Bacterial Glycoconjugates in Relation to Their Immunostimulating Activity (1996) (5)
Therapeutic efficacy of 5-fluorouracil prodrugs using endogenous serum proteins as drug carriers: a new strategy in drug delivery system. (1995) (5)
Synthesis of Alanyl-1-aminoethanesulfonic Acid (1977) (5)
Synthesis of neoglycoproteins containing 5-O-phosphorylated Kdomonosaccharide, 4-O- and 5-O-phosphorylated α-Kd↬(2 6)-2-acetamido-2-deoxy- -D-glucopyranosyl disaccharide residues (1996) (5)
Immunologieal and Antitumor Activities of Synthetic 6-O-Mycoloyl-N-acetylmuramyldipeptides (1977) (5)
Zur Chemie des Ingenols, I Ingenol und einige seiner Derivate/ On the Chemistry of Ingenol, I Ingenol and Some of its Derivatives (1981) (5)
Solid-phase synthesis of oligosaccharides using novel alkyne-type linkers: Selection of reactive sites on the support by Sonogashira reaction (2002) (5)
Modified Polyanionic Polymers for Enhanced Cell Membrane Interaction (1992) (5)
Synthesis and biological activities of biscarboxymethyl lipid a analogues (2006) (5)
Synthetic Study of Peptidoglycan Partial Structures. Synthesis of Tetrasaccharide and Octasaccharide Fragments. (2010) (5)
A Divergent Synthesis of Lipid A and Its Chemically Stable Unnatural Analogues. (1999) (5)
Chemistry of Lipid A (1988) (5)
Nε-(carboxymethyl)-l-lysine in the acid hydrolysate of Sagittaria pygmaea (1979) (5)
Immunogenicity and antigenicity of natural and synthetic Escherichia coli lipid A. (1987) (5)
Effects of chemical modifications of the glutamic acid residue in N-acetylmuramyl peptides on the immunoadjuvancies of the molecules. (1977) (4)
Synthetic lipid A with endotoxic and related biological activities, comparable to a natural lipid A from E. coli, re-mutant (1985) (4)
Synthetic Study of a Bioactive 3H-Labeled Analogue of Lipid A (1996) (4)
Liberation of serotonin in rabbit platelets by various bacterial cell walls, a water-soluble cell wall fragment and synthetic 6-o-mycoloyl n-acetylmuramyl tetrapeptide (1980) (4)
Purification and Endotoxin-Like Bioactivities of a Novel Amphiphile from Mycobacterium bovis BCG (1990) (4)
Chemical Synthesis of a Biosynthetic Precursor of Lipid A with a Phosphorylated Tetraacyl Disaccharide Structure. (1987) (4)
Chemical synthesis of endotoxin. (1990) (4)
Preparation of N-Acetylmuramyl-L-[U-14C]alanyl-D-isoglutamine via a Novel Synthetic Route (1979) (4)
Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies". (2010) (4)
Preparation of Novel Pyranosyl Fluorides (I) of 3-Deoxy-D-manno-2-octulosonic Acid (KDO) Feasible for Synthesis of KDO α-Glycosides. (1988) (4)
Synthesis and Antitumor Activity of N-Acetylmuramyl-L-alanyl-D-isoglutamine 6-Phosphate and Its Lipophilic Derivatives (1986) (4)
Nonvolatile Constituents of the Leaves of Japaniese Peppec (1968) (4)
3-Nitro-2-pyridyl Glycoside as Donor for Chemical Glycosylation and Its Application to Chemoenzymatic Synthesis of Oligosaccharide. (1999) (3)
Oligosaccharide Synthesis by Affinity Separation Based on Molecular Recognition Between Podand Ether and Ammonium Ion. (2005) (3)
Synthetic Study on Lipoteichoic Acid of Gram Positive Bacteria. Part 1. Synthesis of the Proposed Fundamental Structure of Streptococcus pyogenes Lipoteichoic Acid (1993) (3)
Characterization of antibody responses induced by different synthetic adjuvants to the Plasmodium falciparum major merozoite surface precursor protein, gp 195. (1990) (3)
A novel crosslinking reagent and its application for the detection and isolation of heparin-binding protein(s) on the platelet surface. (1999) (3)
Activation of human complement system by enzymatic digests of bacterial cell wall peptidoglycans and 6-o-acyl-muramyl peptides (1980) (3)
Enzymatic Synthesis of 4-Methylumbelliferyl Glycosides of Trisaccharide and Core Tetrasaccharide, Gal(β1-3)Gal(β1-4)Xyl and GlcA(β1-3)Gal(β1-3)Gal(β1-4)Xyl, Corresponding to the Linkage Region of Proteoglycans. (1998) (3)
Identification of Trisaccharide Xy1α1→3Xy1α1→3Glc in Human Urine (1994) (3)
A direct continuous spectrophotometric assay for glycosidases with 3-nitro-2-pyridyl glycosides by tautomerization of 2-hydroxy-3-nitropyridine. (2002) (3)
Synthesis and Antitumor Activity of Lipid A Analogs (I) Having a Phosphonooxyethyl Group with α- or β-Configuration at Position 1. (1991) (3)
Synthesis and biological activities of analogs of a lipid A biosynthetic precursor: 1-O-phosphonooxyethyl-4'-O-phosphono-disaccharides with (R)-3-hydroxytetradecanoyl or tetradecanoyl groups at positions 2, 3, 2' and 3'. (1991) (3)
Synthesis of Helicobacter pylori Lipid A and Its Analogue Using p-(Trifluoromethyl)benzyl Protecting Group. (2000) (3)
Novel Photo Affinity Cross-Linking Resin for the Isolation of Heparin Binding Proteins (2000) (3)
Enhancement of Cell Membrane Affinity and Biological Activity of Polyanionic Polymers (1994) (3)
Synthetic Chemistry and Function of Bacterial Cell Surface Glycoconjugates (2002) (3)
Chemoenzymatic Synthesis of a Trisaccharide–Serine Conjugate, Gal(β1-3)Gal(β1-4)Xyl(β1-O)–L-Ser, Use of Galactosyl Fluoride as a Donor for Transglycosylation (2001) (2)
Synthesis of 4-o-(N-acetyl-β-D-glucosaminyl)-6-o-acyl-N-acetylmuramyl-L-alanyl-D-isoglutamine (1980) (2)
Stereoselective Glycosylation and Oligosaccharide Synthesis on Solid Support Using a 4-Azido-3-chlorobenzyl Group for Temporary Protection (2000) (2)
LPS-dependent changes in the expression of 57 kDa and 53 kDa cell membrane proteins without participation of CD14 (1999) (2)
Research articleCytokine-inducing glycolipids in the lipoteichoic acid fraction from Enterococcus hirae ATCC 9790 (1995) (2)
Synthesis of Allyl 3‐Deoxy‐D‐manno‐2‐octulopyranosidic Acid 4‐ and 5‐ Phosphates. (1992) (2)
SYNTHESIS OF STREPTOLIDINE FROM D-XYLOSE (1977) (2)
Synthesis of lipid A and its analogues for investigation of the structural basis for their bioactivity (2005) (2)
Enhancement of antitumor activity of OK-432 (picibanil) by Triton X-114 phase partitioning. (2008) (2)
Erratum to “Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies” (2010) (2)
Endotoxic Properties of Chemically Synthesized Lipid A Analogs (1989) (2)
Infrared Spectroscopic Conformational Study of Synthetic Lipid a Part Structures (1997) (2)
Synthesis and Functional Study of Bacterial Glycoconjugates Triggering the Innate Immune System of Higher Animals (2010) (2)
Regioselective Reductive Opening of 4,6‐O‐Benzylidene Acetals of Glucose or Glucosamine Derivatives by BH3×Me2NH‐BF3×OEt2. (1997) (1)
Structures of the Diterpene-Carboxylic Acids from Solidago altissima L. (1972) (1)
Small-Scale Solid-Phase O-Glycopeptide Synthesis of Linear and Cyclized Hexapeptides from Blood-Clotting Factor IX Containing O-(. alpha.-D-Xyl-1 3-α-D-Xyl-1 3-β-D-Glc)-L- Ser. (1993) (1)
Novel Oxidatively Removable Protecting Groups and Linkers for Solid- Phase Synthesis of Oligosaccharides (1997) (1)
An Efficient Procedure for Synthesis of Phosphopeptides through the Benzyl Phosphate-Protection by the Boc Mode Solid-Phase Method. (1994) (1)
Identification of Branched Peptidic Structures that Recognize Immunostimulating Glycoconjugate Lipid A from Encoded Combinatorial Libraries (2001) (1)
Synthesis of 13C-Labeled Biosynthetic Precursor of Lipid A and Its Analogue with Shorter Acyl Chains. (1999) (1)
Synthesis based on affinity separation : A new methodology for high-throughput synthesis using affinity tags (2005) (1)
Combinations of acyl derivatives of n-acetylmuramyl peptides and vehicles in immunopotentiation with the maximum immunostimulating and minimum adverse effects (1980) (1)
Structure and synthesis of lipid A. (2009) (1)
Saponins of Sanguisorba oflicinalis L. (1968) (1)
Epithelioid granuloma formation by muramyl dipeptide (MDP) (1980) (1)
New Methodology for High Throughput Solution‐Phase Synthesis: Affinity Purification by Using Crown Ether and Ammonium Ion Interaction. (2000) (1)
A Novel Method for Stereoselective Glycosidation with Thioglycosides: Promotion by Hypervalent Iodine Reagents Prepared from PhIO and Various Acids. (1996) (1)
Upregulation of PGRPs by chemically synthesized pathogen-associated molecular patterns via Toll-like receptors, NOD1 and NOD2 in oral epithelial cells (2005) (1)
Acid-stable phosphate-protection for phosphoamino acids in the synthesis of phosphopeptides (1993) (1)
Mechanism of Immunostimulating Action of Peptidoglycan, Investigation with Synthetic Partial Structures (2005) (1)
Stimulation of locomotion of human monocytes by bacterial cell walls and muramylpeptides (1982) (1)
New Efficient Route for Synthesis of Lipid A by Using Affinity Separation. (2002) (1)
Benzyl Trityl Ether and DDQ as New Tritylating Reagents. (1998) (1)
Identification of trisaccharide Xyl alpha 1-->3Xyl alpha 1-->3Glc in human urine. (1994) (1)
4-Nitrobenzyl Group for Protection of Hydroxyl Functions. (1990) (1)
4‐Azido‐3‐chlorobenzyl Ether, New Protection for Hydroxy Functions. (1997) (1)
Activation of Trichloroacetimidates Montmorillonite as Catalys in Glicosidation and Benzyllation Reactions (1994) (0)
Propargyloxycarbonyl and Propargyl Groups for Protection of Amino, Hydroxy, and Carboxy Functions (1999) (0)
SOLID-PHASE SYNTHESIS OF OLIGOSACCHARIDES: USE OF 4-AZIDO-3-CHLOROBENZYL GROUP AS A KEY FOR BOTH TEMPORARY PROTECTION AND CATCH-AND-RELEASE PURIFICATION (2002) (0)
Effective Fluorescent and -Iodine Labelling of Proteins with a New Labelling Reagent (1994) (0)
65(P-22) Structure and Function of Lipid As from Helicobacter pylori strains (2001) (0)
Contractile effects of bacterial cell walls and related compounds (1980) (0)
A Stereoselective Glycosidation Using Thioglycosides, Activation by Combination of N‐Bromosuccinimide and Strong Acid Salts. (1995) (0)
Chemoenzymatic Synthesis of a Trisaccharide—Serine Conjugate, Gal(β1‐3)Gal(β1‐4)Xyl(β1‐O)—L‐Ser, Use of Galactosyl Fluoride as a Donor for Transglycosylation. (2001) (0)
First Total Synthesis of the Re‐Type Lipopolysaccharide. (2001) (0)
Novel Cytokine-Inducing Macromolecular Glycolipids from Gram-Positive Bacteria (2000) (0)
Synthesis of Rubrivivax gelatinosus Lipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities. (2008) (0)
P-151 LIPOPROTEIN IS RESPONSIBLE FOR THE IMMUNOBIOLOGICAL ACTIVITIES IN LIPOTEICHOIC ACID FRACTION (2006) (0)
CHAPTER 9:Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-Containing Membrane (2014) (0)
Synthesis and Biological Activities of Lipid A Analogs Possessing β-Glycosidic Linkage at 1-Position Synthesis of Lipid A Analogs (2003) (0)
Chemical Synthesis of Lipid A and Analogues (2011) (0)
Exo-Vivo Cytokine Inducing Activity of Hydrophobized Poly(Maleic Acid-Alt-7, 12-Dioxaspiro-[5,6]-Dodec-9-Ene) [Poly(MA-CDA)] (1996) (0)
P-293 Investigation for the bioactive conformation of immunostimulating glycoconjugate lipid A : the synthesis of conformationally constrained analogues (2006) (0)
Novel Dehydrative Glycosylation by Using Acid Anhydride and TMSClO4. (1999) (0)
New Phosphoryl Protecting Groups for Synthesis of Phosphopeptides by Boc Method (1995) (0)
Chemical Structure of Escherichia Coli Lipid A. Chemical Synthesis of 1-Dephospho-Derivative of Echerichia Coli Lipid A. (1985) (0)
PREPARATION OF N-ACETYLMURAMYL-L-(U-14C)ALANYL-D-ISOGLUTAMINE VIA A NOVEL SYNTHETIC ROUTE (1979) (0)
SYNTHESIS OF ENDURACIDIDINE, A COMPONENT AMINO ACID OF ANTIBIOTIC ENDURACIDIN (1976) (0)
Novel Molecular Clamp Method for Anomeric Stereocontrol of Glycosylation. (2000) (0)
P-181 Synthesis of peptidoglycan fragments for elucidation of immunostimulating mechanism (2006) (0)
Structure and synthesis of active site of endotoxin, lipid A. (1984) (0)
Enzymatic Preparation of (S)-3-Hydroxytetradecanoic Acid and Synthesis of Unnatural Analogues of Lipid A Containing the (S)-Acid. (1997) (0)
Design and Synthesis of Peptides Passing Through the Blood-Brain Barrier. (1998) (0)
Increase of thromboplastin activity in bone marrow cells by synthetic lipid A analogs (1986) (0)
On a Practical Synthesis of β‐Hydroxy Fatty Acid Derivatives. (1995) (0)
Synthesis of an Analogue of Biosynthetic Precursor Ia of Lipid A by an Improved Method: A Novel Antagonist Containing Four (S)-3-Hydroxy Fatty Acids. (1996) (0)
Structure and Synthesis ofLipidA (0)
Cellular requirements for interleukin 1 induction with lipopolysaccharides (1988) (0)
RECEPTORS AND SIGNALING PATHWAYS FOR GRAM‐POSITIVE CELL WALL COMPOUNDS.: 676 (1997) (0)
Chemical Synthesis and Biological Activities of Two Disaccharide Dipeptides Corresponding to the Repeating Units of Bacterial Peptidoglycan. (1986) (0)
New Affinity Purification Methods Based on Specific Molecular Recognition and Their Application to High Throughput Solution-phase Synthesis (2000) (0)
Nitropyridyl Glycosides: New Glycosyl Donors for Enzymatic Transglycosylation. (1999) (0)
The Steric Structures of Diterpene Carboxylic Acids from Solidago altissima L. (1973) (0)
New macromolecules for targeting of bioactive compounds (1994) (0)
An Efficient Method for the Assembly of Sulfated Oligosaccharides Using Reductive Amination. (2001) (0)
[Inhibitory effect of lipopolysaccharides, natural lipid A and synthetic lipid A on growth of murine B cell lines, CYG 34 and CYG 101]. (1988) (0)
Iodosobenzene-Triflic Anhydride as an Efficient Promoter for Glycosidation Reaction Using Thioglycosides as Donors. (2010) (0)
4-Pivaloylaminobenzyl Ether, a New Temporary Protection for Hydroxyl Functions. (1992) (0)
Synthesis of Oligomeric Assemblies of a Platelet‐Binding Key Disaccharide in Heparin and Their Biological Activities. (2001) (0)
Preparation of Phosphoamino Acid Derivatives with Acid Stable O- Phosphono-Protection for the Boc-Mode Solid-Phase Synthesis of Phosphopeptides. (1995) (0)
Synthesis of New Serine-Linked Oligosaccharides in Blood-Clotting Factors VII and IX and Protein Z. The Syntheses of O-α-D- Xylopyranosyl-(1 3)-D-glucopyranose, O-α-D- Xylopyranosyl-(1 3)-O-α-D-xylopyranosyl-(1 3)- D-glucopyranose, and Their Conjugates with Serine. (1992) (0)
New Efficient Synthesis of a Biosynthetic Precursor of Lipid A. (1997) (0)
Elevated promotion of prostacyclin production by synthetic lipid A analogs in aged human endothelial cells in culture (1995) (0)
Total Synthesis o f Lipid A , Active Principle o f Bacterial End otoxin (2006) (0)
The Structure of Dehydrokolavenic Acid (1973) (0)
Analysis of heparin-platelets interaction at the molecular level (1996) (0)
Affinity photo crosslinking for the efficient identification and isolation of heparin-binding proteins (2000) (0)
P-131 Oligosaccharides Synthesis Based on Affinity Separation (SAS) : Application towards Hemagglutinin Ligand Library (2006) (0)
Macrophages the Signaling of Apoptosis in Bacteria-Faced A Dominant Role of Toll-Like Receptor 4 in (2003) (0)
Chemical and biological degradation of 5-fluorouracil prodrugs having high serum albumin binding potencies. (1993) (0)
The Fragrant Components of the Flower-buds of Zingiber Mioga Roscoe (1966) (0)
Synthesis of lipid A and its novel analogues for investigation of the structural and conformational bases for their bioactivity (2004) (0)
CHEMOENZYMATIC SYNTHESIS OF GAL(BETA 1-3)GAL(BETA 11-4)XYL(BETA )-L-SER AND GAL(BETA 1-3)GAL(BETA 1-4)XYL(BETA )-MU BY THE USE OF BETA -D-GALACTOSIDAS E (1996) (0)
SYNTHESIS OF N-ACETYL-β-D-GLUCOSAMINYL-(1→4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTA# MINE (1979) (0)
Protection of Hydroxyl Functions by 4-Azidobutyryl Group and its Selective Removal. (1986) (0)
A New Synthesis of 3-Deoxy-D-manno-2-octulosonic Acid (KDO) (I) from D-Mannose. (1988) (0)
Synthesis of [ 3 H ]-Labeled Bioactive Lipid A Analogs and Their Use for Detection of Lipid A-Binding Proteins on Murine Macrophages 1 Synthesis of [ 3 H ]-Labeled Lipid A Analogs (2001) (0)
Application of 4-Azidobenzyl Group to Protection of Hydroxyl Functions. (1992) (0)
Stimulation ofMigration ofHumanMonocytes byBacterial CellWallsandMuramylPeptides (1982) (0)
Synthesis of β(1-4)-Linked Disaccharides of N-Acetylglucosamine and N-Acetylmuramic Acid by Their Direct Condensation. (1986) (0)
Activation of Trichloroacetimidates Using Montmorillonite as a Heterogeneous Acid Catalyst-Convenient Glycosidation and Benzylation Reactions. (1993) (0)
SYNTHESIS OF 4-O-(N-ACETYL-β-D-GLUCOSAMINYL)-6-O-ACYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLU# TAMINE (1981) (0)
Biological Activity ofSynthetic Phosphonooxyethyl Analogs ofLipid A andLipid A Partial Structures (1992) (0)
Synthesis and Biological Activity of a Model Disaccharide Containing a Key Unit in Heparin for Binding to Platelets. (1996) (0)
Syn thetic Chem is try and Func tion of Bac te rial Cell Sur face Glycoconjugates (2002) (0)
Synthesis and Antitumor Activity of N-Acetylmuramyl-L-alanyl-D-isoglutamine 6-Phosphate and Its Lipophilic Derivatives. (1987) (0)
[Structure and chemical synthesis of lipid A]. (1986) (0)
Synthesis and Biological Activities of Lipid A Analogues Possessing β‐Glycosidic Linkage at 1‐Position. (2003) (0)
4-Azidobutyryl Group for Temporary Protection of Hydroxyl Functions. (1986) (0)
EFFICIENT SYNTHESIS OF LIPID A ANALOGUES BY AFFINITY SEPARATION (2002) (0)
Evaluation of clustering effect of partial structure in heparin (2000) (0)
Structural requirements for interleukin 1 induction with lipopolysaccharides (1988) (0)
A Novel Method for Activation of Thioglycosides, Combination of N- Bromosuccinimide, and Triflic Acid Salts. (2010) (0)
Adjuvant Activity of 6-0-Acyl-Muramyldipeptides to Enhance Primary Cellular and Humoral Immune Responses in Guinea Pigs: (0)
Linker compound, ligand complex and methods for their preparation (2005) (0)
S17.11 Functional fluorescent labeling of carbohydrates and its application to lipopolysaccharide (1993) (0)
Chemical Synthesis of Lipoteichoic Acid, Biological Active Glycoconjugate of Gram-Positive Bacterial Cell Surface (1992) (0)
IL-6-Inducing Capacity Influences Their Conformation and The Charge of Endotoxin Molecules (2013) (0)
New Bioactive Macromolecular Glycolipids from Bacterial Cell Surface (1996) (0)
The Chemical Synthesis of Lipid A (2020) (0)

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