Shozo Izui

Q: What Schools Are Affiliated With Shozo Izui

Shozo Izui is affiliated with the following schools: Vrije Universiteit Amsterdam, University of Cologne, Kansai Medical University, University of Geneva

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Shozo Izui

Engineering

#5334

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#6585

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Mechanical Engineering

#466

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#510

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Applied Physics

#1521

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#1553

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engineering Degrees

Shozo Izui

Biology

#10078

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#13368

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Immunology

#624

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#644

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Neuroscience

#1522

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#1573

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biology Degrees

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Engineering
Biology

Shozo Izui's Degrees

PhD Mechanical Engineering University of Tokyo

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Shozo Izui's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains (1978) (1588)
Induction of various autoantibodies by mutant gene lpr in several strains of mice. (1984) (399)
Critical role of galectin-3 in phagocytosis by macrophages. (2003) (393)
Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. (2001) (383)
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. (2002) (328)
A fish oil diet rich in eicosapentaenoic acid reduces cyclooxygenase metabolites, and suppresses lupus in MRL-lpr mice. (1985) (298)
In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus (1976) (289)
Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice. (1996) (288)
Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. (1978) (283)
Prolactin influences autoimmune disease activity in the female B/W mouse. (1991) (228)
Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus (1979) (202)
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. (2010) (189)
Markedly Different Pathogenicity of Four Immunoglobulin G Isotype-Switch Variants of an Antierythrocyte Autoantibody Is Based on Their Capacity to Interact in Vivo with the Low-Affinity Fcγ Receptor III (2000) (186)
Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes (1977) (169)
Induction of murine autoimmune disease by chronic polyclonal B cell activation (1983) (168)
(NZW x BXSB)F1 hybrid. A model of acute lupus and coronary vascular disease with myocardial infarction (1981) (162)
Complement Activation Selectively Potentiates the Pathogenicity of the IgG2b and IgG3 Isotypes of a High Affinity Anti-Erythrocyte Autoantibody (2002) (153)
Long-term observations of autoimmune-prone mice treated for autoimmune disease by allogeneic bone marrow transplantation. (1989) (151)
IgM rheumatoid factors in mice injected with bacterial lipopolysaccharides. (1979) (145)
Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice. (1997) (145)
Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus (1993) (143)
Interleukin-4 Protects against a Genetically Linked Lupus-like Autoimmune Syndrome (1997) (133)
TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity (2002) (129)
The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus‐like syndrome in (NZW × C57BL/6)F1 male mice, but not in C57BL/6 male mice (1988) (128)
Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus (2007) (127)
Failure to detect circulating DNA--anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus. (1977) (126)
Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice. (1996) (126)
FcγRIII (CD16)-Deficient Mice Show IgG Isotype-Dependent Protection to Experimental Autoimmune Hemolytic Anemia (1998) (124)
Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms. (1990) (123)
Evidence for Genes in Addition to Tlr7 in the Yaa Translocation Linked with Acceleration of Systemic Lupus Erythematosus1 (2008) (123)
IgG3 is the major source of cryoglobulins in mice. (1989) (119)
Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice. (2002) (110)
The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility (2011) (104)
Autoimmune response to DNA, red blood cells, and thymocyte antigens in association with polyclonal antibody synthesis during experimental African trypanosomiasis. (1979) (102)
Molecular and cellular basis for pathogenicity of autoantibodies: lessons from murine monoclonal autoantibodies (2006) (101)
Male determined accelerated autoimmune disease in BXSB mice: transfer by bone marrow and spleen cells. (1980) (100)
Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause autoimmune hemolytic anemia by two distinct pathogenic mechanisms. (1990) (100)
H‐2‐linked control of the Yaa gene‐induced acceleration of lupus‐like autoimmune disease in BXSB mice (1992) (99)
Linkage of a major quantitative trait locus to Yaa gene‐induced lupus‐like nephritis in (NZW × C57BL/6)F1 mice (1998) (99)
The Yaa Mutation Promoting Murine Lupus Causes Defective Development of Marginal Zone B Cells1 (2003) (98)
Genetic basis of murine lupus. (2004) (98)
Retroviral gp70 immune complexes in NZB x NZW F2 mice with murine lupus nephritis (1981) (98)
Cryoglobulinemia induced by monoclonal immunoglobulin G rheumatoid factors derived from autoimmune MRL/MpJ-lpr/lpr mice. (1987) (96)
Mechanism for induction of anti-DNA antibodies by bacterial lipopolysaccharides in mice; II. Correlation between anti-DNA induction and polyclonal antibody formation by various polyclonal B lymphocyte activators. (1977) (95)
The Yaa Gene Model of Systemic Lupus Erythematosus (1995) (92)
Role of Gas6 in erythropoiesis and anemia in mice. (2008) (92)
High Pathogenic Potential of Low-Affinity Autoantibodies in Experimental Autoimmune Hemolytic Anemia (1999) (92)
A MEMBER OF A NEW VH GENE FAMILY ENCODES ANTI‐BROMELINIZED MOUSE RED BLOOD CELL AUTOANTIBODIES (1988) (90)
A comparative immunologic analysis of several murine strains with autoimmune manifestations. (1980) (87)
Emerging roles of TLR7 and TLR9 in murine SLE. (2009) (87)
Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. (2003) (87)
Autoimmunity after induction of neonatal tolerance to alloantigens: role of B cell chimerism and F1 donor B cell activation. (1986) (86)
Functional analysis of T cell subsets from mice bearing the lpr gene. (1985) (85)
Selective pathogenicity of murine rheumatoid factors of the cryoprecipitable IgG3 subclass. (1992) (84)
Enhanced production of glomerular extracellular matrix in a new mouse strain of high serum IgA ddY mice. (1996) (82)
Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions1 (2008) (82)
Cd22a PRE-mRNA Dysregulated Expression of the Cd22 Gene as a Result of a Short Interspersed Nucleotide Element Insertion in Cd22a Lupus-Prone Mice1 (2000) (81)
Differential Contribution of Three Activating IgG Fc Receptors (FcγRI, FcγRIII, and FcγRIV) to IgG2a- and IgG2b-Induced Autoimmune Hemolytic Anemia in Mice1 (2008) (80)
Immunoglobulin heavy chain constant region determines the pathogenicity and the antigen-binding activity of rheumatoid factor. (1993) (80)
Mast cells induce autoantibody-mediated vasculitis syndrome through tumor necrosis factor production upon triggering Fcgamma receptors. (1999) (80)
Mouse FcγRII is a negative regulator of FcγRIII in IgG immune complex‐triggered inflammation but not in autoantibody‐induced hemolysis (2000) (77)
Determination of anti-DNA antibodies by a modified 125I-labelled DNA-binding test. Elimination of non-specific binding of DNA to non-immunoglobulin basic proteins by using an anionic detergent. (1976) (77)
Induction of "wire-loop" lesions by murine monoclonal IgG3 cryoglobulins. (1992) (76)
Subclass-restricted IgG polyclonal antibody production in mice injected with lipid A-rich lipopolysaccharides (1981) (75)
Hyperprolactinemia in male NZB/NZW (B/W) F1 mice: accelerated autoimmune disease with normal circulating testosterone. (1994) (74)
Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (FcμR) (2012) (74)
Toll-Like Receptor 9 Stimulation Induces Aberrant Expression of a Proliferation-Inducing Ligand by Tonsillar Germinal Center B Cells in IgA Nephropathy. (2017) (73)
Differential effect of the autoimmune yaa and ipr genes on the acceleration of lupus‐like syndrome in mrl/mpj mice (1989) (71)
Selective suppression of retroviral gp70-anti-gp70 immune complex formation by prostaglandin E1 in murine systemic lupus erythematosus (1980) (70)
Reduced development of CD4−8−B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules (1995) (70)
Prostaglandin E1 inhibits T-cell proliferation and renal disease in MRL/1 mice. (1981) (68)
Circulating anti-DNA-rheumatoid factor complexes in MRL/1 mice. (1980) (68)
The Role of Complement in Cryoglobulin-Induced Immune Complex Glomerulonephritis1 (2005) (68)
The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis. (2010) (67)
Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)- Yaa- bone marrow chimeric mice (1991) (66)
Prevention of systemic lupus erythematosus in autoimmune BXSB mice by a transgene encoding I-E alpha chain (1993) (66)
Polyclonal B cell activation arises from different mechanisms in lupus-prone (NZB x NZW)F1 and MRL/MpJ-lpr/lpr mice. (1993) (65)
Effect of prostaglandin E on immune complex nephritis in NZB/W mice. (1979) (64)
Separation of the New Zealand Black Genetic Contribution to Lupus from New Zealand Black Determined Expansions of Marginal Zone B and B1a Cells1 (2004) (64)
Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4- subset in lpr mice. (1985) (63)
Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells (2007) (63)
Mechanism for induction of anti-DNA antibodies by bacterial lipopolysaccharides in mice. I. Anti-DNA induction by LPS without significant release of DNA in circulating blood. (1977) (62)
Down-regulated expression of TWEAK mRNA in acute and chronic inflammatory pathologies. (2000) (62)
Lessons from BXSB and Related Mouse Models (2000) (61)
Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. (2001) (60)
Identification of retroviral gp70 and anti-gp70 antibodies involved in circulating immune complexes in NZB X NZW mice (1981) (59)
The Yaa gene‐mediated acceleration of murine lupus: Yaa− T cells from non‐autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo (1995) (59)
Inhibition of T cells proliferation and SLE-like syndrome of MRL/1 mice by whole body or total lymphoid irradiation. (1980) (59)
Murine serum glycoprotein gp70 behaves as an acute phase reactant (1982) (58)
Induction of plasminogen activator inhibitor type 1 in murine lupus-like glomerulonephritis. (1995) (58)
Dissection of BXSB Lupus Phenotype Using Mice Congenic for Chromosome 1 Demonstrates That Separate Intervals Direct Different Aspects of Disease1 (2004) (58)
Differential Role of Three Major New Zealand Black-Derived Loci Linked with Yaa-Induced Murine Lupus Nephritis1 (2005) (56)
Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice (2004) (56)
Genetic Control of Glycoprotein 70 Autoantigen Production and Its Influence on Immune Complex Levels and Nephritis in Murine Lupus1 (2000) (53)
Distinct clonotypes of anti-DNA antibodies in mice with lupus nephritis. (1985) (53)
Autoantigen Glycoprotein 70 Expression Is Regulated by a Single Locus, Which Acts as a Checkpoint for Pathogenic Anti-Glycoprotein 70 Autoantibody Production and Hence for the Corresponding Development of Severe Nephritis, in Lupus-Prone BXSB Mice1 (2001) (52)
Effects of parturition, suckling and pseudopregnancy on variables of disease activity in the B/W mouse model of systemic lupus erythematosus. (1993) (52)
Contributions of Ea(z) and Eb(z) MHC genes to lupus susceptibility in New Zealand mice. (1998) (51)
The Th2 Lymphoproliferation Developing in LatY136F Mutant Mice Triggers Polyclonal B Cell Activation and Systemic Autoimmunity1 (2006) (50)
Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus. (2005) (49)
Control of separate pathogenic autoantibody responses marks MHC gene contributions to murine lupus. (1999) (48)
Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. (2009) (48)
Enriched lipid diet accelerates lupus nephritis in NZB x W mice. Synergistic action of immune complexes and lipid in glomerular injury. (1983) (48)
Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses. (2002) (48)
Development of a model of early-onset IgA nephropathy. (2012) (47)
Inhibition of cryoprecipitation of murine IgG3 anti‐dinitrophenyl (DNP) monoclonal antibodies by anionic DNP‐amino acid conjugates (1989) (47)
Analysis of MHC class II genes in the susceptibility to lupus in New Zealand mice. (1999) (47)
Differentially Regulated Expression and Function of CD22 in Activated B-1 and B-2 Lymphocytes1 (2002) (46)
Role of endogenous retroviruses in murine SLE. (2010) (46)
FcgammaRIII (CD16)-deficient mice show IgG isotype-dependent protection to experimental autoimmune hemolytic anemia. (1998) (45)
The Yaa gene abrogates the major histocompatibility complex association of murine lupus in (NZB x BXSB)F1 hybrid mice. (1994) (45)
An MRL/MpJ-lpr/lpr substrain with a limited expansion of lpr double-negative T cells and a reduced autoimmune syndrome. (1993) (45)
Acute SLE in F1 hybrids between SB/Le and NZW mice; prominently enhanced formation of gp70 immune complexes by a Y chromosome-associated factor from SB/Le mice. (1984) (45)
Recombinant murine IL-3 fails to stimulate T or B lymphopoiesis in vivo, but enhances immune responses to T cell-dependent antigens. (1988) (44)
Constitutive expression of bcl-2 in B cells causes a lethal form of lupuslike autoimmune disease after induction of neonatal tolerance to H- 2b alloantigens (1996) (43)
Inhibition of B Cell Death Causes the Development of an IgA Nephropathy in (New Zealand White × C57BL/6)F1-bcl-2 Transgenic Mice1 (2004) (43)
IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independent of complement activation and FcαRI. (2010) (42)
IgG3 cryoglobulins in autoimmune MRL-lpr/lpr mice: immunopathogenesis, therapeutic approaches and relevance to similar human diseases. (1993) (41)
Low-calorie diet selectively reduces expression of retroviral envelope glycoprotein gp70 in sera of NZB x NZW F1 hybrid mice (1981) (41)
Selective Up-Regulation of Intact, but Not Defective env RNAs of Endogenous Modified Polytropic Retrovirus by the Sgp3 Locus of Lupus-Prone Mice1 (2009) (40)
IgM and IgA anti-erythrocyte autoantibodies induce anemia in a mouse model through multivalency-dependent hemagglutination but not through complement activation. (2007) (40)
Enhancement of autoantibody pathogenicity by viral infections in mouse models of anemia and thrombocytopenia☆ (2004) (39)
Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment. (1995) (39)
The role of the Yaa gene in lupus syndrome. (1994) (38)
The Sgp3 Locus on Mouse Chromosome 13 Regulates Nephritogenic gp70 Autoantigen Expression and Predisposes to Autoimmunity1 (2003) (38)
Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background. (2003) (37)
Effect of Long-Term Anti-CD4 or Anti-CD8 Treatment on the Development oflprCD4−CD8−Double Negative T Cells and of the Autoimmune Syndrome in MRL-lpr/lprMice (1995) (37)
Selective enhancing effect of the Yaa gene on immune responses against self and foreign antigens (1995) (37)
Enhanced Susceptibility to Lupus Contributed from the Nonautoimmune C57BL/10, But Not C57BL/6, Genome1 (2000) (37)
Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice. (2003) (37)
Contribution of NZB Autoimmunity 2 to Y-Linked Autoimmune Acceleration-Induced Monocytosis in Association with Murine Systemic Lupus1 (2006) (36)
Type II cryoglobulinemia. (1995) (36)
Level of galactosylation determines cryoglobulin activity of murine IgG3 monoclonal rheumatoid factor. (2002) (35)
Diverse antigen specificity of erythrocyte‐reactive monoclonal autoantibodies from NZB mice (1996) (35)
Variable region sequences of pathogenic anti‐mouse red blood cell autoantibodies from autoimmune NZB mice (1990) (35)
Induction of high serum levels of retroviral env gene products (gp70) in mice by bacterial lipopolysaccharide. (1981) (35)
Pathogenic Role of a Proliferation-Inducing Ligand (APRIL) in Murine IgA Nephropathy (2015) (34)
In C 57 Bl / 6 mice FcγRIIB deficiency amplifies spontaneous autoimmunity caused by other loci (2009) (34)
Exacerbation of Autoantibody-Mediated Hemolytic Anemia by Viral Infection (2000) (34)
Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus1 (2006) (32)
Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. (2008) (31)
Role of galactosylation in the renal pathogenicity of murine immunoglobulin G3 monoclonal cryoglobulins. (2001) (31)
Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice. (1997) (30)
Sialylation determines the nephritogenicity of IgG3 cryoglobulins. (2012) (29)
A Transgenic Mouse Model of Autoimmune Glomerulonephritis and Necrotizing Arteritis Associated with Cryoglobulinemia1 (2002) (28)
Induction Of Thymocytotoxic Autoantibodies After Injection of Bacterial lipopolysaccharides in Mice (1979) (28)
Investigation into the Presence of and Serological Response to XMRV in CFS Patients (2011) (28)
Self-associating IgG rheumatoid factors in MRL/l autoimmune mice. (1984) (27)
Prevention of murine lupus by an I‐E α chain transgene: Protective role of I‐E α chain‐derived peptides with a high affinity to I‐Ab molecules (1996) (27)
Transient T and B cell activation after neonatal induction of tolerance to MHC class II or Mls alloantigens. (1991) (27)
Lack of Galactosylation Enhances the Pathogenic Activity of IgG1 but Not IgG2a Anti-Erythrocyte Autoantibodies (2014) (26)
O-glycosylated IgA rheumatoid factor induces IgA deposits and glomerulonephritis. (2012) (25)
Genetic susceptibility to PolyI:C-induced IFNα/β-dependent accelerated disease in lupus-prone mice (2006) (25)
A Novel Locus Regulates Both Retroviral Glycoprotein 70 and Anti-Glycoprotein 70 Antibody Production in New Zealand Mice When Crossed with BALB/c1 (2004) (25)
Autoimmune syndrome after induction of neonatal tolerance to alloantigens. CD4+ T cells from the tolerant host activate autoreactive F1 B cells. (1989) (25)
Dissection of Genetic Mechanisms Governing the Expression of Serum Retroviral gp70 Implicated in Murine Lupus Nephritis1 (2008) (24)
Association between nuclear antigens and endogenous retrovirus in the generation of autoantibody responses in murine lupus. (2004) (24)
Enzyme-linked immunosorbent assay for detection of retroviral gp70 and gp70-anti-gp70 immune complexes in sera from SLE mice. (1988) (24)
Autoimmune syndrome after induction of neonatal tolerance to alloantigens: effects of in vivo treatment with anti-T cell subset monoclonal antibodies. (1987) (24)
Anti-IgM treatment of C57BL/6-1pr/1pr mice: depletion of B cells reduces 1pr gene-induced lymphoproliferation and mononuclear cell vasculitis. (1989) (23)
Glomerulopathy induced by IgG3 anti-trinitrophenyl monoclonal cryoglobulins derived from non-autoimmune mice. (1994) (23)
T helper cell subsets in the pathogenesis of systemic lupus erythematosus. (1996) (23)
A Critical Role for FcγRIIB in the Induction of Rheumatoid Factors1 (2004) (23)
A Critical Role for Sialylation in Cryoglobulin Activity of Murine IgG3 Monoclonal Antibodies1 (2005) (22)
Effect of long-term anti-CD4 or anti-CD8 treatment on the development of lpr CD4- CD8- double negative T cells and of the autoimmune syndrome in MRL-lpr/lpr mice. (1995) (22)
Polymorphonuclear leukocytes play a key role in the generation of "wire-loop" lesions induced by a murine IgG3 rheumatoid factor. (1996) (22)
Mouse FcgammaRII is a negative regulator of FcgammaRIII in IgG immune complex-triggered inflammation but not in autoantibody-induced hemolysis. (2000) (22)
TLR-mediated up-regulation of serum retroviral gp70 is controlled by the Sgp loci of lupus-prone mice. (2010) (22)
Differential control of CD22 ligand expression on B and T lymphocytes, and enhanced expression in murine systemic lupus. (2003) (22)
Protection of Murine Lupus by the Ead Transgene Is MHC Haplotype-Dependent1 (2000) (21)
Selective production of interleukin 3 (IL 3) and granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) in vitro by murine L3T4 T cells: lack of spontaneous IL 3 and GM‐CSF production by Ly‐2−/ L3T4− lpr subset (1988) (21)
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. (1982) (21)
Murine autoimmune hemolytic anemia resulting from Fc gamma receptor-mediated erythrophagocytosis: protection by erythropoietin but not by interleukin-3, and aggravation by granulocyte-macrophage colony-stimulating factor. (1992) (21)
Murine cryoglobulinemia: pathogenic and protective IgG3 self-associating antibodies. (1991) (21)
Expression of aberrant forms of CD22 on B lymphocytes in Cd22a lupus-prone mice affects ligand binding. (2006) (21)
The role of E-selectin for neutrophil activation and tumor metastasis in vivo. (1997) (20)
Treatment with high doses of anti-IgM prevents, but with lower doses accelerates autoimmune disease in (NZW x BXSB)F1 hybrid mice. (1987) (20)
Galactosylation of IgG1 modulates FcγRIIB-mediated inhibition of murine autoimmune hemolytic anemia. (2013) (20)
Spontaneous production of anti‐mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice (1990) (20)
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice. (2014) (19)
TLR7/9-mediated monocytosis and maturation of Gr-1(hi) inflammatory monocytes towards Gr-1(lo) resting monocytes implicated in murine lupus. (2011) (19)
Rheumatoid factors in mice bearing the lpr or gld mutation. Selective production of rheumatoid factor cryoglobulins in MRL/MPJ‐lpr/lpr mice (1992) (19)
Role of neutrophils in murine cryoglobulinemia (1998) (19)
Differential Activation of Anti-Erythrocyte and Anti-DNA Autoreactive B Lymphocytes by the Yaa Mutation1 (2005) (19)
Association of elevated serum glycoprotein gp70 with increased gp70 immune complex formation and accelerated lupus nephritis in autoimmune male BXSB mice. (1984) (19)
Suppression of B cell development and antibody responses in mice with polyclonal rabbit and monoclonal rat anti-IgM antibodies. I. Characterization of the suppressed state. (1985) (18)
Autoantibody repertoire analysis in normal and lupus-prone mice. (1989) (18)
Evidence that Yaa-induced loss of marginal zone B cells is a result of dendritic cell-mediated enhanced activation. (2010) (18)
Abundant a proliferation-inducing ligand (APRIL)-producing macrophages contribute to plasma cell accumulation in immunoglobulin G4-related disease (2018) (18)
Identification of 2 major loci linked to autoimmune hemolytic anemia in NZB mice. (2005) (18)
Immunopathogenesis of systemic lupus erythematosus. (1984) (18)
Impact of a Three Amino Acid Deletion in the CH2 Domain of Murine IgG1 on Fc-Associated Effector Functions1 (2008) (18)
Polymorphisms in the Cd22 gene of inbred mouse strains (1999) (18)
Resistance to tolerance induction is not prerequisite to development of murine SLE. (1984) (17)
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and prote (2002) (17)
Molecular and cellular basis for pathogenicity of autoantibodies. (1994) (17)
The Bxs6 Locus of BXSB Mice Is Sufficient for High-Level Expression of gp70 and the Production of gp70 Immune Complexes1 (2007) (17)
CD4+CD25+ T Cell-Dependent Inhibition of Autoimmunity in Transgenic Mice Overexpressing Human Bcl-2 in T Lymphocytes1 (2007) (17)
The lupus-prone BXSB strain: the Yaa gene model of systemic lupus erythematosus (2004) (17)
Abnormal IgG galactosylation in MRL‐lpr/lpr mice: Pathogenic role in the development of arthritis (2001) (17)
Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice. (2006) (17)
Therapeutic effect of early thymic irradiation in (NZB x NZW)F1 mice, associated with a selective decrease in the levels of IgG3 and gp70-anti-gp70 immune complexes. (1995) (16)
Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice. (2008) (16)
Presumptive role of 129 strain-derived Sle16 locus in rheumatoid arthritis in a new mouse model with Fcγ receptor type IIb-deficient C57BL/6 genetic background. (2011) (16)
Effect of Helper and/or Cytotoxic T-Lymphocyte Depletion on Low-Dose Streptozocin-Induced Diabetes in C57BL/6J Mice (1988) (16)
E-selectin binding promotes neutrophil activation in vivo in E-selectin transgenic mice. (1996) (15)
CELLULAR SITES OF IMMUNOGLOBULINS (1971) (15)
The cellular basis for resistance to induction of tolerance in BXSB SLE male mice. (1982) (15)
Effect of lipid A-associated protein and lipid A on the expression of lipopolysaccharide activity. I. Immunological activity. (1980) (14)
IgM rheumatoid factors in Guatemalan onchocerciasis. (1984) (14)
Interleukin 3 perfusion prevents death due to acute anemia induced by monoclonal antierythrocyte autoantibody (1990) (14)
LatY136F knock-in mouse model for human IgG4-related disease (2018) (14)
Murine SLE - aetiology and pathogenesis. (1980) (13)
Protease nexin 1 in the murine kidney: glomerular localization and up-regulation in glomerulopathies. (1996) (13)
Circulating immune complexes and their possible relevance to other immunological parameters in Guatemalan onchocerciasis. (1983) (13)
Interleukin‐12p40 overexpression promotes interleukin‐12p70 and interleukin‐23 formation but does not affect bacille Calmette–Guérin and Mycobacterium tuberculosis clearance (2007) (13)
Prevention of murine cryoglobulinemia and associated pathology by monoclonal anti-idiotypic antibody. (1989) (13)
Pathogenesis of the delayed phase of Rauscher virus-induced thrombocytopenia. (1986) (13)
Tubular up-regulation of clusterin mRNA in murine lupus-like nephritis. (1998) (12)
Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis. (1999) (12)
Effect of genetic background on Ea(d) transgene-mediated protection from murine lupus. (1998) (12)
Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease. (2010) (12)
Two‐Step Mechanism of Virus‐induced Autoimmune Hemolytic Anemia (2007) (12)
MHC-linked control of murine SLE. (1999) (11)
Autoimmune hemolytic anemia. (1994) (11)
Resistance to tolerance induction to human gammaglobulin (HGG) in autoimmune BXSB/MpJ mice: functional analysis of antigen-presenting cells and HGG-specific T helper cells. (1988) (11)
Rheumatoid factor autoantibody‐binding site: a molecular analysis using monoclonal antibodies with dual anti‐tnp and anti‐igg activities* (1989) (11)
Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus. (1990) (11)
Igh-C allotype-linked control of anti-DNA production and clonotype expression in mice infected with Plasmodium yoelii. (1988) (11)
Effect of cyclosporin A and zidovudine on immune abnormalities observed in the murine acquired immunodeficiency syndrome. (1992) (10)
Epitope-Dependent Inhibition of T Cell Activation by the Ea Transgene: An Explanation for Transgene-Mediated Protection from Murine Lupus1 (2004) (10)
Recombinant interleukin-2 therapy of systemic lupus erythematosus in the New Zealand black/New Zealand white mouse. (1989) (10)
Pathogenesis of autoimmune hemolytic anemia in New Zealand black mice. (1994) (10)
The contribution of I-Abm12 to phenotypic and functional alterations among T-cell subsets in NZB mice. (1993) (10)
Three Sgp loci act independently as well as synergistically to elevate the expression of specific endogenous retroviruses implicated in murine lupus. (2013) (9)
The occurrence of antibodies against single-stranded DNA in the sera of patients with acute and chronic leukaemia. (1976) (9)
IgG rheumatoid factors and cryoglobulins in mice bearing the mutant gene lpr (lymphoproliferation) (2004) (9)
BXSB/long-lived Is a Recombinant Inbred Strain Containing Powerful Disease Suppressor Loci1 (2007) (9)
Quantitation of retroviral gp70 antigen, autoantibodies, and immune complexes in extravascular space in arthritic MRL-lpr/lpr mice. Use of a subcutaneously implanted tissue cage model. (1987) (9)
Isotype-dependent pathogenicity of autoantibodies: analysis in experimental autoimmune hemolytic anemia (2001) (8)
The spontaneous development of thymocytotoxic antibodies in athymic nude mice and its suppression after transfer of syngeneic thymocytes (1978) (8)
B-cell overexpression of Bcl-2 cooperates with p21 deficiency for the induction of autoimmunity and lymphomas. (2010) (8)
A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice (1994) (8)
Sgp3 and TLR7 stimulation differentially alter the expression profile of modified polytropic retroviruses implicated in murine systemic lupus. (2012) (7)
Enforced Bcl‐2 expression in B lymphocytes induces rheumatoid factor and anti‐DNA production, but the Yaa mutation promotes only anti‐DNA production (2004) (7)
Immunological pathogenesis of experimental glomerulonephritis induced by some infectious and toxic agents. (1983) (7)
Genesis and pathogenicity of anti-DNA antibodies. (1976) (7)
Interstitial Pneumonitis and Hepatitis after Transfer of Bone Marrow Cells Bearing the Ipr Gene to Irradiated Recipients: A Disease Due to Large Granular Leueocytes? (1987) (7)
Pathogenic role of anti-DNA antibodies in murine lupus nephritis. (1985) (7)
A case report of crystalline light chain inclusion-associated kidney disease affecting podocytes but without Fanconi syndrome (2019) (7)
Cellular sites of immunoglobulins. 3. Localization of IgG-, IgA-, IgM- and their kappa and lambda light chain-containing cells in human palatine tonsils. (1971) (7)
Suppression of transferred BXSB male SLE disease by female spleen cells. (1982) (6)
Genes and Genetics of Murine Lupus (2007) (6)
Sgp3 and Sgp4 control expression of distinct and restricted sets of xenotropic retroviruses encoding serum gp70 implicated in murine lupus nephritis. (2011) (6)
Murine models for systemic lupus erythematosus (1996) (6)
The Sgp3 locus derived from the 129 strain is responsible for enhanced endogenous retroviral expression in macroH2A1-deficient mice. (2010) (6)
Association of glycoprotein gp70 with progression or attenuation of murine lupus nephritis. (1985) (6)
Lack of association of Vβ8+ T cells with lupus‐like syndrome in MRL‐lpr/lpr mice (1994) (5)
Lack of anti‐DNA precursors in λ chain‐bearing B Iymphocytes in (NZB × NZW)F1 mice. Evidence for the contribution of Vχ genes to anti‐DNA specificity (1991) (5)
Suppression of experimental lupus nephritis by aberrant expression of the soluble E‐selectin gene (2002) (5)
Prevention of Systemic Lupus Erythematosus in Autoimmune BXSB Mice by a Transgene Encoding I-E cr Chain By Ram6n Merino,* Masahiro Iwamoto,* Liliane Fossati,* (1993) (5)
Anti-Ia treatment prevents lupus-like autoimmune syndrome in mice neonatally tolerized to alloantigens. (1993) (5)
Induction of acute thrombocytopenia and infection of megakaryocytes by Rauscher murine leukemia virus reflect the genetic susceptibility to leukemogenesis (1983) (5)
Presence of a very small population of Thy-1+, L3T4+ cells producing large amounts of IL-3 in young athymic nude mice. (1989) (4)
Complexes with murine systemic lupus erythematosus. (1979) (4)
Superantigen-reactive CD 4 + T Cells Are Required to Stimulate B Cells after Infection with Mouse Mammary Tumor Virus (2003) (4)
O-linked glycosylation determines the nephritogenic potential of IgA rheumatoid factor. (2014) (4)
Protection of Murine Systemic Lupus by the Ea Transgene without Expression of I-E Heterodimers1 (2008) (4)
Variability of the inhibition by total immunoglobulin of in vitro autoantibody-mediated erythrophagocytosis by mouse macrophages. (2006) (4)
CD4+ T cells play a major role for IgM and IgG anti‐DNA production in mice infected with Plasmodium yoelii (1990) (4)
An experimental model of cryoglobulin-associated vasculitis in mice (2009) (4)
Autoimmunity following neonatal tolerance to alloantigens: role of donor I-A and I-E molecules. (1995) (3)
Anti--DNA antibodies in patients with leukemia and lymphoma. (1976) (3)
Evidence that lithium chloride treatment of female NZB/W mice does not influence autoantibody profiles in this murine model of svstemic lupus erythematosus (1997) (3)
Prevention of murine lupus by an I-E alpha chain transgene: protective role of I-E alpha chain-derived peptides with a high affinity to I-Ab molecules. (1996) (3)
Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors (2022) (2)
Clonality of the spontaneous immune response to DNA in murine lupus. (1986) (2)
Mechanisms of genetic control of murine systemic lupus erythematosus (2004) (2)
Involvement of Fcα/μ Receptor in IgM Anti-Platelet, but Not Anti–Red Blood Cell Autoantibody Pathogenicity in Mice (2015) (2)
The autoimmune accelerating yaa mutation does not accelerate murine AIDS. (2000) (2)
Autoantibody-Mediated Vasculitis Syndrome Through Tumor Necrosis Factor Production Upon Triggering Fc g Receptors (1999) (2)
Growth Arrest-Specific Gene 6 (Gas6) Deficiency in Mice Alleviates Graft-versus-Host Disease (GVHD) in the Liver. (2004) (2)
Prostaglandin e1 prevents glomerular cellular changes in autoimmune mrl/1 mice. Abstr. (1981) (2)
Gas 6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease (2010) (2)
Genes predisposing to autoimmunity augment constitutive major histocompatibility complex class II‐associated presentation of the self‐antigen IgG2abin vivo (2000) (2)
Experimental analysis of the generation of pathogenic immune complexes resulting from immonoblogulin interactions (1986) (1)
Evidence for an IFN-inducible gene, Ifi202, in the susceptibility to systemic lupus (2003) (1)
Interim evaluation of the cooperative studies of immunoglobulin intravenous (IgG i. v.) in childhood idiopathic thrombocytopenic purpura (ITP) (1985) (1)
Bacterial lipopolysaccharides. Identification of circulating dna and renal localization of dna-anti-dna complexes. (1977) (1)
Spontaneous b cell activation and autoantibody formation in autoimmune mice. Abstr. (1978) (1)
hemolytic anemia in a mouse model Liposomal clodronate as a novel agent for treating autoimmune (2013) (1)
Recent Advances in Systemic Lupus Erythematosus (1984) (1)
Epidermal and splenic antigen-presenting cell function in a retrovirally induced murine immunodeficiency syndrome (MAIDS) (2004) (1)
IgG 2 b Fc-Associated Effector Functions in the CH 2 Domain for Murine IgG 2 a and Crucial Role of Aspartic Acid at Position 265 Nishimura and Shozo Izui (2008) (1)
Pathogenic role of rheumatoid factors. (1994) (1)
Immune complex diseases resulting from idiotypic or allogenic interactions (1984) (1)
Critical Amplification by Gas6 of the Epo-Dependent Erythropoietic Response to Anemia: Novel Opportunities for Anemia Treatment. (2004) (1)
Inhibition of retroviral gp70-anti-gp70 immune complex formation and prolongation of lifespan by dietary restriction in (nzb x nzw) f1 mice. Abstr. (1981) (1)
Obituary - Professor Hervé Favre 1937–1999 (2000) (1)
Imbalance towards Th 1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice TAKAHASHI , Satoru (2019) (1)
Experimental model of murine cryoglobulinemia induced by monoclonal antibodies and modulation by anti-idiotypic Antibodies (2005) (1)
An autoimmune MRL/Mp-Ipr/Ipr mouse-derived monoclonal IgG antibody stimulates cytokine production in bone-marrow-derived cell line by cross-linking of a cell surface antigen and Fc receptor. (1994) (1)
The Sgp 3 locus derived from the 129 strain is responsible for enhanced endogenous retroviral expression in macroH 2 A 1-deficient mice BAUDINO , (2017) (1)
SLE and other connective tissue diseases (animal models) (WS-017) Chairpersons: Takayuki Sumida, Sachiko Hirose (2010) (0)
Implicated in Murine Lupus Nephritis the Expression of Serum Retroviral gp70 Dissection of Genetic Mechanisms Governing (2013) (0)
Receptors γ Tumor Necrosis Factor Production Upon Triggering Fc Mast Cells Induce Autoantibody-Mediated Vasculitis Syndrome Through (2013) (0)
Immune Complex Levels and Nephritis in Autoantigen Production and Its Influence on Genetic Control of Glycoprotein 70 (2000) (0)
Systemic Lupus Monocytosis in Association with Murine Acceleration-InducedY-Linked Autoimmune Contribution of NZB Autoimmunity 2 to (2006) (0)
Involvement of Virus-Induced Interferon Production in IgG Autoantibody-Mediated Anemia (2021) (0)
THE PATHOGENETIC ROLE OF TONSILLAR B CELL PRODUCING APRIL IN IGA NEPHROPATHY (2014) (0)
[Pathophysiological implications of antigen-antibody complexes (author's transl)]. (1975) (0)
Subclass restricted igg polyclonal autoantibody formation in mice injected with lipid a-rich lipopolysaccharides. Abstr. (1980) (0)
[Lupus mice--the role of its genetic factors]. (1983) (0)
招聘講演2 Immunopathogenesis of Lupus Nephritis: An Update of Recent Developments in Murine Models (1994) (0)
Contents, Vol. 53, 1985 (1985) (0)
Subject Index, Vol. 53, 1985 (1985) (0)
cDNA sequence analysis and characterization of a cytokine-inducing monoclonal antibody derived from autoimmune MRL/MP-lpr/lpr mouse. (1995) (0)
Dysregulated Expression of theCd22Gene as a Result of a Short Interspersed Nucleotide Element Insertion inCd22 Lupus-Prone Mice (2000) (0)
Cell Activation and Systemic Autoimmunity Mutant Mice Triggers Polyclonal B Y136F Lat The Th2 Lymphoproliferation Developing in (2006) (0)
Production of gp 70 Immune Complexes for High-Level Expression of gp 70 and the Locus of BXSB Mice Is Sufficient Bxs (2007) (0)
Response to Comment on “The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility” (2011) (0)
Association of retroviral gp70 immune complexes with glomeruloneph- ritis in f2 generation of nzb x nzw mice. Abstr. (1981) (0)
Implications physio-pathologiques des complexes antigène-anticorps (1975) (0)
The Y-linked autoimmune accelerator (YAA) gene is sufficient to break immunological tolerance (2005) (0)
Genetic analysis of host mechanism controlling endogenous murine leukemia virus gene expression (2002) (0)
FP304ABERRANT APRIL EXPRESSION IN TONSILLAR GERMINAL CENTER B CELLS IN IGA NEPHROPATHY PATIENTS (2015) (0)
Different Aspects of Disease Demonstrates That Separate Intervals Direct Mice Congenic for Chromosome 1 Dissection of BXSB Lupus Phenotype Using (2004) (0)
Contents, Vol. 42, 1975 (1975) (0)
Enhanced phagocytosis of auto antibodies-opsonized blood cells by macrophages from virally infected mice. (INM3P.440) (2014) (0)
Professor A. Grumbach 1895-1975 (1975) (0)
Lupus-Prone Mice a Cd22 Interspersed Nucleotide Element Insertion in Gene as a Result of a Short Cd22 of the PRE-mRNA Dysregulated Expression a Cd22 (2000) (0)
Response to Comment on “The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility” (2011) (0)
Protection of murine systemic lupus erythematosus by an I-E alpha-chain transgene. (1998) (0)
This information is current as-Induced Murine Lupus Nephritis Yaa Zealand Black-Derived Loci Linked with Differential Role of Three Major New Shozo (2004) (0)
[DNA-immune complex]. (1975) (0)
Expression and Predisposes to Autoimmunity Regulates Nephritogenic gp70 Autoantigen Locus on Mouse Chromosome 13 Sgp3 The (2003) (0)
Experimental Approach to the Immunopathology of Viral-Induced Thrombpcytopenia (1985) (0)
Immunopathogenesis of lupus nephritis: new insights from experimental models. (1995) (0)
MRL-lpr mice metabolites, and suppresses lupus in acid reduces cyclooxygenase A fish oil diet rich in eicosapentaenoic (2010) (0)
Mutation Yaa by the and Anti-DNA Autoreactive B Lymphocytes Differential Activation of Anti-Erythrocyte (2004) (0)
Immunological aspects of autoimmune diseases. (1984) (0)
Dissecting the role of FcγR in the pathogenesis of autoimmune hemolytic anemia (1997) (0)
Lupus-Prone Mice Locus of Sgp 3 Polytropic Retrovirus by the RNAs of Endogenous Modified env Defective Selective Up-Regulation of Intact , but Not (2009) (0)
Cell transfer studies in autoimmune bxsb mice. Abstr. (1979) (0)
25 years of Springer Seminars in Immunopathology (2003) (0)
Suppression of male bxsb sle by female bxsb spleen cells. Abstr. (1981) (0)
Review of Special Molds(Chemically Bonded Sand Mold, Full Mold, Sand Reclamation) (1996) (0)
Fc (cid:103) RIII (CD16)-Deﬁcient Mice Show IgG Isotype-Dependent Protection to Experimental Autoimmune Hemolytic Anemia (1998) (0)
T Helper Subsets and Corresponding IgG Subclass Responses in the Pathogenesis of Murine Lupus-Like Autoimmune Syndrome (2001) (0)
Genetic analysis of the NZW contribution to lupus-like autoimmune disease in (NZW × C57BL/6.Yaa) F1 mice (1997) (0)
LymphocytesFunction of CD22 in Activated B-1 and B-2 Differentially Regulated Expression and (2002) (0)
Example of the Pathogenic Potential of Two Sets of Autoantibodies: Anti-RBC and IgG3 RF Cryoglobulins (2013) (0)
Crossed with BALB / c Antibody Production in New Zealand Mice Glycoprotein 70 and Anti-Glycoprotein 70 A Novel Locus Regulates Both Retroviral Kotzin (2004) (0)
In Memoriam: Peter A. Miescher, 1923–2020 (2020) (0)
429 complexes at the surface or inside basement membranes in kidney and in skin (2003) (0)
Circulating gp70-anti-gp70 complexes and their role in the pathogenesis of murine systemic lupus erythematosus. Abstr. (1979) (0)
Chapter 18 – Genes and Genetics of Murine Lupus (2007) (0)
Protection of murine systemic lupus erythematosus by an I-E α-chain transgene (1998) (0)
T-depleted bone marrow cells are the basis of resistance to induction of tolerance in male bxsb sle mice. Abstr. (1982) (0)
Transgene Is MHC Haplotype-Dependent d Ea Protection of Murine Lupus by the (1999) (0)
on Murine Lupus Stimulatory and Inhibitory IgG Fc Receptors Genetic Dissection of the Effects of (2006) (0)
Modulation of an early and lethal autoimmune diabetes in transgenic mice by IL-4 overexpression and treatment with anti-IFN-γ antibody (1999) (0)
Anti-Erythrocyte Autoantibodies Pathogenic Activity of IgG1 but Not IgG2a Lack of Galactosylation Enhances the (2013) (0)
Associated with Cryoglobulinemia Glomerulonephritis and Necrotizing Arteritis A Transgenic Mouse Model of Autoimmune (2002) (0)
Enzymatically Generated Low Carbohydrate Antibodies as a Novel Treatment for Autoimmune Disease (2008) (0)
Lymphocytes Overexpressing Human Bcl-2 in T Autoimmunity in Transgenic Mice T Cell-Dependent Inhibition of + CD 25 + CD 4 Izui (2007) (0)
Fc-Associated Effector Functions CH 2 Domain of Murine IgG 1 on Impact of a Three Amino Acid Deletion in the Nishimura (2008) (0)
Variability of the inhibition by total immunoglobulin of in vitro autoantibody‐mediated erythrophagocytosis by mouse macrophages (2006) (0)
Relevance of polyclonal antibody formation to the development of autoimmunity : the model of African trypanosomiasis. (1979) (0)
RED CELL AUTOANTIBODIES (2007) (0)
SLE and other connective tissue diseases (animal models) (PP-017) (2010) (0)

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