Shunichi Shimasaki
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Computer Science
Shunichi Shimasaki's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Shunichi Shimasaki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin (1986) (1072)
- The bone morphogenetic protein system in mammalian reproduction. (2004) (740)
- Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6). (1991) (687)
- Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. (1998) (474)
- Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone. (1987) (431)
- A functional bone morphogenetic protein system in the ovary. (1999) (349)
- Bone Morphogenetic Protein-15 (2000) (318)
- Molecular Basis of Bone Morphogenetic Protein-15 Signaling in Granulosa Cells* (2003) (317)
- Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human. (1991) (316)
- Integral role of GDF‐9 and BMP‐15 in ovarian function (2011) (310)
- Bone Morphogenetic Protein-15 Inhibits Follicle-stimulating Hormone (FSH) Action by Suppressing FSH Receptor Expression* (2001) (306)
- Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells (2007) (293)
- The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle (2003) (281)
- A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: Its role in regulating granulosa cell mitosis (2002) (270)
- FOLLISTATIN BINDS TO BOTH ACTIVIN AND INHIBIN THROUGH THE COMMON BETA-SUBUNIT (1991) (253)
- Molecular cloning of the cDNAs encoding a novel insulin-like growth factor-binding protein from rat and human. (1990) (250)
- Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell. (1993) (241)
- Complementary deoxyribonucleic acid (cDNA) cloning and DNA sequence analysis of rat ovarian inhibins. (1987) (240)
- Primary structure of the human follistatin precursor and its genomic organization. (1988) (239)
- Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. (2002) (237)
- Isolation and molecular cloning of insulin-like growth factor-binding protein-6. (1991) (236)
- Follistatin and Activin: A Potential Intrinsic Regulatory System within Diverse Tissues (1991) (230)
- Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain. (1989) (225)
- Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA. (1988) (217)
- Biological Function and Cellular Mechanism of Bone Morphogenetic Protein-6 in the Ovary* (2001) (207)
- A Novel Role of Follistatin, an Activin-binding Protein, in the Inhibition of Activin Action in Rat Pituitary Cells (1997) (194)
- Follistatin gene expression in the ovary and extragonadal tissues. (1989) (187)
- A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse. (2006) (184)
- Effect of Bone Morphogenetic Protein-7 on Folliculogenesis and Ovulation in the Rat1 (2001) (182)
- Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein (1989) (172)
- Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad. (1987) (171)
- Effect of Intracellular Interactions on the Processing and Secretion of Bone Morphogenetic Protein-15 (BMP-15) and Growth and Differentiation Factor-9 (2003) (170)
- A homodimer of the β-subunits of inhibin a stimulates the secretion of pituitary follicle stimulating hormone (1986) (168)
- Recombinant expression of human follistatin with 315 and 288 amino acids: chemical and biological comparison with native porcine follistatin. (1991) (167)
- An insulin-like growth factor-binding protein in ovarian follicular fluid blocks follicle-stimulating hormone-stimulated steroid production by ovarian granulosa cells. (1989) (165)
- Development of specific antibodies to rat insulin-like growth factor-binding proteins (IGFBP-2 to -6): analysis of IGFBP production by rat granulosa cells. (1993) (162)
- The physiology of folliculogenesis: the role of novel growth factors. (2001) (158)
- Follicle-stimulating hormone regulates oocyte growth by modulation of expression of oocyte and granulosa cell factors. (2005) (152)
- A novel function of bone morphogenetic protein-15 in the pituitary: selective synthesis and secretion of FSH by gonadotropes. (2002) (150)
- Follistatin inhibits the function of the oocyte-derived factor BMP-15. (2001) (138)
- The Role of the Oocyte in Folliculogenesis (2000) (136)
- Tissue-specific expression of four insulin-like growth factor-binding proteins (1, 2, 3, and 4) in the rat ovary. (1991) (135)
- Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA. (1989) (135)
- A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice1 (2015) (129)
- Molecular biology and physiological role of the oocyte factor, BMP-15 (2005) (124)
- Porcine follistatin gene structure supports two forms of mature follistatin produced by alternative splicing. (1988) (124)
- Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. (2005) (119)
- Effects of bone morphogenetic protein‐7 (BMP‐7) on primordial follicular growth in the mouse ovary (2004) (116)
- Expression of inhibin beta A and beta B, follistatin and activin-A receptor messenger ribonucleic acids in the rat seminiferous epithelium. (1992) (115)
- Regulation of insulin-like growth factor-binding protein (IGFBP) expression by breast cancer cells: use of IGFBP-1 as an inhibitor of insulin-like growth factor action. (1992) (115)
- Characterization of an insulin-like growth factor binding protein (IGFBP-4) produced by the B104 rat neuronal cell line: chemical and biological properties and differential synthesis by sublines. (1991) (115)
- Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family. (1992) (108)
- The role of bone morphogenetic proteins in ovarian function. (2019) (103)
- Follistatin specifically inhibits pituitary follicle stimulating hormone release in vitro. (1987) (100)
- Regulation of inhibin subunit gene expression by FSH and estradiol in cultured rat granulosa cells. (1989) (98)
- Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals? (2004) (96)
- Follistatin binds to both activin and inhibin through the common subunit. (1991) (93)
- Cyclic changes in follistatin messenger ribonucleic acid and its protein in the rat ovary during the estrous cycle. (1991) (93)
- Functional and Molecular Characterization of Naturally Occurring Mutations in the Oocyte-secreted Factors Bone Morphogenetic Protein-15 and Growth and Differentiation Factor-9* (2004) (93)
- Stage dependent expression of inhibin α and β-B subunits during the cycle of the rat seminiferous epithelium (1989) (89)
- Bone morphogenetic protein-15 in the zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation. (2006) (86)
- Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE (1991) (85)
- Structural characterization of a follicle-stimulating hormone action inhibitor in porcine ovarian follicular fluid. Its identification as the insulin-like growth factor-binding protein. (1990) (85)
- Localization of insulin-like growth factor-binding protein-5 messenger ribonucleic acid in rat ovaries during the estrous cycle. (1992) (83)
- Cyclic changes in insulin-like growth factor-binding protein-4 messenger ribonucleic acid in the rat ovary. (1992) (82)
- Role of ERK1/2 in the differential synthesis of progesterone and estradiol by granulosa cells. (2001) (81)
- IGF-binding protein mRNAs in the human fetus: tissue and cellular distribution of developmental expression. (1996) (74)
- Conserved sequence motifs in the small subunit of human general transcription factor TFIIE (1991) (72)
- Molecular Aspects and Clinical Relevance of GDF9 and BMP15 in Ovarian Function. (2018) (72)
- Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice. (2008) (65)
- Difference between follistatin isoforms in the inhibition of activin signalling: activin neutralizing activity of follistatin isoforms is dependent on their affinity for activin. (2000) (62)
- Expression of insulin-like growth factor-binding protein-2 and -3 messenger ribonucleic acid in the porcine ovary: localization and physiological changes. (1992) (61)
- Structural and Biophysical Coupling of Heparin and Activin Binding to Follistatin Isoform Functions* (2007) (61)
- Inhibins and activins. (1988) (60)
- Gauge-Higgs unification and quark-lepton phenomenology in the warped spacetime (2006) (60)
- Identification of a novel binding protein for insulin-like growth factors in adult rat serum. (1989) (58)
- Localization of the heparin binding site of follistatin (1992) (58)
- Hormonal regulation of insulin-like growth factor II and insulin-like growth factor binding protein expression by breast cancer cells in vivo: evidence for stromal epithelial interactions. (1994) (58)
- Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis (2017) (56)
- The heparin binding site of follistatin is involved in its interaction with activin. (1995) (54)
- Expression and regulation of insulin-like growth factor-binding protein-1, -2, -3, and -4 messenger ribonucleic acids in purified rat Leydig cells and their biological effects. (1993) (52)
- Extrapituitary actions of gonadotropin-releasing hormone: stimulation of insulin-like growth factor-binding protein-4 and atresia. (1994) (51)
- Essential role of the oocyte in estrogen amplification of follicle-stimulating hormone signaling in granulosa cells. (2005) (51)
- Control of inhibin production by primate granulosa cells. (1989) (47)
- Regulation of testicular inhibin subunit messenger ribonucleic acid levels in vivo: effects of hypophysectomy and selective follicle-stimulating hormone replacement. (1989) (46)
- A homodimer of the beta-subunits of inhibin A stimulates the secretion of pituitary follicle stimulating hormone. (1986) (46)
- Regulation of inhibin α- and βB-subunit mRNA levels in rat sertoli cells (1990) (44)
- Porcine ovarian granulosa cells secrete insulin-like growth factor-binding proteins-4 and -5 and express their messenger ribonucleic acids: regulation by follicle-stimulating hormone and insulin-like growth factor-1. (1994) (43)
- Structural and functional characterization of the rat follistatin (activin-binding protein) gene promoter (1993) (41)
- Insulin-like growth factor binding protein-4, -5 and -6 mRNAs in the human fetus: localization to sites of growth and differentiation? (1993) (41)
- Impaired production of BMP-15 and GDF-9 mature proteins derived from proproteins WITH mutations in the proregion (2010) (40)
- Increased androgen response to follicle-stimulating hormone administration in women with polycystic ovary syndrome. (2008) (40)
- Insulin-like growth factor binding protein-3 gene expression is restricted to involuting corpora lutea in rat ovaries. (1993) (39)
- Structure of the rat insulin-like growth factor binding protein-4 gene. (1993) (38)
- Insulin-like growth factor binding proteins show distinct patterns of expression in the rat uterus. (1994) (38)
- Stage-specific cellular regulation of inhibin α-subunit mRNA expression in the rat seminiferous epithelium (1991) (37)
- Characterization of the post‐translational modification of recombinant human BMP‐15 mature protein (2008) (37)
- Follistatin concentrations in follicular fluid of normal and polycystic ovaries. (1995) (36)
- Phosphorylation of bone morphogenetic protein-15 and growth and differentiation factor-9 plays a critical role in determining agonistic or antagonistic functions. (2008) (36)
- Analysis of spatial and temporal expression patterns of bone morphogenetic protein family members in the rat uterus over the estrous cycle. (2004) (36)
- Gonadotropin and cAMP modulation of IGE binding protein production in ovarian granulosa cells. (1992) (35)
- Differential control of activin, inhibin and follistatin proteins in cultured rat granulosa cells. (1993) (35)
- Regulation of insulin-like growth factor binding proteins in ovarian cancer cells by oestrogen. (1993) (34)
- Cloning of the rat insulin- like growth factor binding protein-5 gene and DNA sequence analysis of its promoter region. (1993) (33)
- Follicle-stimulating hormone regulation of AP-1: inhibition of c-jun and stimulation of jun-B gene transcription in the rat Sertoli cell (1994) (32)
- Interleukin-1 induces insulin-like growth factor binding protein-3 gene expression and protein production by Leydig cells. (1995) (31)
- Cellular distribution of insulin-like growth factor binding protein mRNAs and peptides during rat lung development. (1997) (31)
- Insulin-like growth factor-binding protein-2: the effect of human chorionic gonadotropin on its gene regulation and protein secretion and its biological effects in rat Leydig cells. (1994) (29)
- Endogenous insulin-like growth factor-I is obligatory for stimulation of rat inhibin alpha-subunit expression by follicle-stimulating hormone. (1998) (28)
- Pregnancy-associated plasma protein-a production in rat granulosa cells: stimulation by follicle-stimulating hormone and inhibition by the oocyte-derived bone morphogenetic protein-15. (2004) (26)
- Expression of messenger RNA for insulin-like growth factors and insulin-like growth factor binding proteins by experimental breast cancer and normal breast tissue in vivo. (1992) (26)
- Essential but differential role of FOXL2wt and FOXL2C134W in GDF-9 stimulation of follistatin transcription in co-operation with Smad3 in the human granulosa cell line COV434 (2013) (25)
- Golgi apparatus casein kinase phosphorylates bioactive Ser‐6 of bone morphogenetic protein 15 and growth and differentiation factor 9 (2010) (24)
- Site-specific mutagenesis of human follistatin. (1991) (24)
- Structural characterization of the rat insulin-like growth factor binding protein-6 gene. (1993) (23)
- Structural and functional studies of insulin-like growth factor binding proteins in the ovary. (1993) (22)
- Paracrine regulation of theca androgen production by granulosa cells in the ovary. (2013) (22)
- Effects of estrous cycle stage and pregnancy on follistatin gene expression and immunoreactivity in rat reproductive tissues: progesterone is implicated in regulating uterine gene expression. (1993) (22)
- Gonadotropin-releasing hormone overcomes follicle-stimulating hormone's inhibition of insulin-like growth factor-5 synthesis and promotion of its degradation in rat granulosa cells (1995) (21)
- Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells (2013) (19)
- Purification and partial characterization of a mitogenic factor from bovine liver: structural homology with basic fibroblast growth factor (1986) (16)
- Growth and differentiation factor 9 promotes oocyte growth at the primary but not the early secondary stage in three-dimensional follicle culture (2016) (15)
- Follistatin gene expression by gonadotropin-releasing hormone: A role for cyclic AMP and mitogen-activated protein kinase signaling pathways in clonal gonadotroph LβT2 cells (2009) (15)
- A new hemoglobin variant, hemoglobin Nunobiki [alpha 141 (HC3) Arg----Cys]. Notable influence of the carboxy-terminal cysteine upon various physico-chemical characteristics of hemoglobin. (1985) (14)
- Transforming growth factor-α stimulates insulin-like growth factor binding protein-4 (IGFBP-4) expression and blocks follicle-stimulating hormone regulation of IGFBP-4 production in rat granulosa cells (1997) (13)
- Activin-induced inhibin alpha-subunit production by rat granulosa cells requires endogenous insulin-like growth factor-I. (1998) (12)
- Stage dependent expression of inhibin alpha and beta-B subunits during the cycle of the rat seminiferous epithelium. (1989) (12)
- 5 – Role of Insulin-like Growth Factors (IGF) and IGF-Binding Proteins in Folliculogenesis (1994) (12)
- PAI‐1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF‐β and TNF‐α in mononuclear cells by insulin‐sensitizing drugs (2017) (12)
- Hemoglobin Takamatsu (β120 (GH 3) Lys → Gln): A New Abnormal Hemoglobin Detected in Three Unrelated Families in the Takamatsu Area of Shikoku (1980) (10)
- Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome. (2014) (9)
- Fibroblast Growth Factors as Local Mediators of Gonadal Function (1989) (8)
- Genomic organization and promoter analysis of mouse follistatin-related gene (FLRG) (2002) (8)
- FOXL2C134W-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells (2018) (8)
- GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells. (2013) (7)
- The Survey of Abnormal Hemoglobins in the Kobe District: HB G-Coushatta [β22(B4)GLU→ALA], HB Ankara [β10(A7)ALA→ASP], HB Handa [α90(FG2)LYS→MET], and HB J-HABANA [α71(E20)ALA→GLU] (1986) (7)
- Characterization of follistatin isoforms in early Xenopus embryogenesis. (2000) (7)
- Transforming growth factor-alpha stimulates insulin-like growth factor binding protein-4 (IGFBP-4) expression and blocks follicle-stimulating hormone regulation of IGFBP-4 production in rat granulosa cells. (1997) (7)
- HB Ube-2 (α68[E-17]ASN→ASP): The Second Instance in Japan (1981) (6)
- Hemoglobin Mizushi (alpha 75 [EF4]Asp leads to Gly): a new hemoglobin variant observed in a Japanese family. (1980) (6)
- Diversity of human gamma-globin gene loci including a quadruplicated arrangement (1986) (6)
- Identification and characterization of canine growth differentiation factor-9 and its splicing variant. (2012) (5)
- Activation of follistatin promoter by GnRH in LbetaT2 gonadotroph cells. (2006) (5)
- Ovarian bone morphogenetic proteins in female reproduction (2004) (5)
- FOXO1 Negates the Cooperative Action of FOXL2C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3 (2019) (5)
- Regulation of inhibin alpha- and beta B-subunit mRNA levels in rat Sertoli cells. (1990) (5)
- FOXO1 mitigates the SMAD3/FOXL2C134W transcriptomic effect in a model of human adult granulosa cell tumor (2020) (4)
- Hemoglobin J Bangkok (β56 [D7]Gly → Asp) : A Hemoglobin Variant Discovered by the Hemoglobinopathy Survey in Takamatsu District (1981) (4)
- Abnormal hemoglobins in the Takamatsu district with emphasis on epidemiological characteristics. (1982) (4)
- Diversity of human gamma-globin gene loci including a quadruplicated arrangement. (1986) (4)
- Erratum: Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells (Development vol. 134 (2593-2603)) (2008) (4)
- BMP-15 regulation of ovulation quota in mammals (2006) (4)
- Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse (2021) (3)
- Hemoglobin J Bangkok (beta 56[D7]Gly leads to Asp): a hemoglobin variant discovered by the hemoglobinopathy survey in Takamatsu district. (1981) (2)
- Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells (2008) (2)
- The survey of abnormal hemoglobins in the Kobe district: Hb G-Coushatta [beta 22(B4)Glu----Ala], Hb Ankara (beta 10(A7)Ala----Asp], Hb Handa [alpha 90(FG2)Lys----Met], and Hb J-Habana [alpha 71(E20)Ala----Glu]. (1986) (1)
- Hemoglobin takamatsu (beta 120 (GH 3) Lys leads to Gln): a new abnormal hemoglobin detected in three unrelated families in the takamatsu area of shikoku. (1980) (1)
- Hb Ube-2 (alpha 68[e-17]Asn replaced by Asp): the second instance in Japan. (1981) (1)
- Hb Albany-Suma (alpha 11 [A9] Lys----Asn), a hemoglobin variant with slightly elevated oxygen affinity in Japan. (1984) (1)
- Isolation and partial characterization of follistatin : A single-chain Mr 35 , 000 monomeric protein that inhibits the release of follicle-stimulating hormone ( ovary / pituitary / luteinizing hormone / gonadotropins / porcine foilicular fluid ) (1)
- Manufacturing of uniformly-sized silicon particles for solar cell from molten metal jet by electromagnetic pinch force (2009) (1)
- Insulin-like growth factor-1 (IGF-1) stimulates the IGF binding protein system in rat theca interstitial cells (1995) (1)
- FOXL2-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells (2018) (1)
- Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse (2021) (0)
- Molecular basis of estrogen enhancement of FSH responsiveness in granulosa cells (2013) (0)
- Supplemental information , Hardy et al (2012) (0)
- Follistatin and method thereof for cleaning. (1988) (0)
- The structure of the Activin:Follistatin 315 complex (2007) (0)
- Tissue specific and cyclic expression of insulin-like growth factor binding proteins-1,-2,-3,-4,-5,-6 in the rat oviduct (1995) (0)
- FOXO1 Mitigation of FOXL2C143W/SMAD3 Transcriptomic Landscape in a Model of Granulosa Cell Tumor (2021) (0)
- Concentration and Phosphoinositide Metabolism in Mouse Osteoblasts via Cyclic Adenosine 3 \ 5 '-Monophosphate-Independent Pathways Regulation of Diazepam Binding Inhibitor in Rat Adrenal (2011) (0)
- Prospect for EPM application to environmental technology (2009) (0)
- Mono-dispersed droplets formation from capillary jet of liquid metal by applying an electric field (2018) (0)
- Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis (2017) (0)
- A Novel Mouse Model for Studying the Effects of Cyp17 Overexpression in a Temporal- and Spatial-Specific Manner (2021) (0)
- Control of lnhibin Production by Primate Granulose Cells (1990) (0)
- Isolation and characterization of growth factors from porcine ovarian follicular fluid. (1991) (0)
- FOXO1 mitigates the SMAD3/FOXL2C134W transcriptomic effect in a model of human adult granulosa cell tumor (2021) (0)
- Separation Efficiency of Inclusion Particles from Liquid Aluminum by Electromagnetic Cyclone Separator (2015) (0)
- The Endocrine Society Seventy-First Annual Meeting June 21-24, 1989, Seattle, Washington (1989) (0)
- Morphological and Physiological Correlates of the Polycystic Ovary (2002) (0)
- Molecular basis of oocyte-specific BMPs in regulating folliculogenesis and ovulation rate (2009) (0)
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Shunichi Shimasaki is affiliated with the following schools:
