Silvia Giordano
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Computer Science
Silvia Giordano's Degrees
- PhD Computer Science University of Geneva
- Masters Computer Science University of Geneva
- Bachelors Computer Science University of Geneva
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(Suggest an Edit or Addition)Silvia Giordano's Published Works
Published Works
- Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. (2003) (1296)
- A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family (1994) (1010)
- Drug development of MET inhibitors: targeting oncogene addiction and expedience (2008) (806)
- The Dual Roles of NRF2 in Cancer. (2016) (571)
- Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer. (2013) (560)
- Expression of the Met/HGF receptor in normal and neoplastic human tissues. (1991) (496)
- Tyrosine kinase receptor indistinguishable from the c-met protein (1989) (474)
- The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met (2002) (467)
- Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer. (1995) (466)
- The Semaphorin 4D receptor controls invasive growth by coupling with Met (2002) (454)
- From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage. (2008) (400)
- Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. (2005) (376)
- MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma? (2013) (336)
- Negative receptor signalling. (2003) (331)
- Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas (2000) (327)
- Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages (2008) (260)
- Cancer therapy: can the challenge be MET? (2005) (252)
- Sema4D induces angiogenesis through Met recruitment by Plexin B1. (2005) (239)
- Biosynthesis of the protein encoded by the c-met proto-oncogene. (1989) (218)
- Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy (2010) (216)
- Tumorigenic and metastatic activity of human thyroid cancer stem cells. (2010) (214)
- The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. (1995) (203)
- Interplay between scatter factor receptors and B plexins controls invasive growth (2004) (189)
- YAP activation is an early event and a potential therapeutic target in liver cancer development. (2014) (184)
- MicroRNAs impair MET-mediated invasive growth. (2008) (183)
- Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity. (2006) (175)
- A Natural Hepatocyte Growth Factor/Scatter Factor Autocrine Loop in Myoblast Cells and the Effect of the Constitutive Met Kinase Activation on Myogenic Differentiation (1997) (171)
- Sustained recruitment of phospholipase C-γ to Gab1 is required for HGF-induced branching tubulogenesis (2000) (169)
- Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes (1997) (168)
- MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors. (2010) (166)
- c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase. (1991) (165)
- Specific Uncoupling of GRB2 from the Met Receptor (1996) (164)
- Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies. (2018) (164)
- C-terminal truncated forms of Met, the hepatocyte growth factor receptor (1991) (160)
- Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene. (1993) (158)
- CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes. (2003) (158)
- Plexin‐B3 is a functional receptor for semaphorin 5A (2004) (155)
- Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling (2007) (143)
- Met as a therapeutic target in HCC: facts and hopes. (2014) (142)
- Hepatocyte growth factor and its receptor are required for malaria infection (2003) (141)
- Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists (1999) (140)
- Silencing the MET oncogene leads to regression of experimental tumors and metastases (2008) (135)
- Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. (2011) (133)
- HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells. (2011) (133)
- Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS) (2006) (133)
- Ets up-regulates MET transcription. (1996) (131)
- Molecular cancer therapy: can our expectation be MET? (2008) (130)
- MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer (2011) (127)
- Plexin signaling hampers integrin‐based adhesion, leading to Rho‐kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility (2004) (126)
- MET overexpression turns human primary osteoblasts into osteosarcomas. (2006) (119)
- Reactive Oxygen Species Mediate Met Receptor Transactivation by G Protein-coupled Receptors and the Epidermal Growth Factor Receptor in Human Carcinoma Cells* (2004) (118)
- Mortality prediction in patients with severe septic shock: a pilot study using a target metabolomics approach (2016) (117)
- HGF/MET signalling protects Plasmodium‐infected host cells from apoptosis (2005) (110)
- Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition (2010) (107)
- Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. (2009) (103)
- MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC) (2014) (99)
- Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth. (1998) (96)
- Only a subset of Met-activated pathways are required to sustain oncogene addiction. (2009) (94)
- A point mutation in the MET oncogene abrogates metastasis without affecting transformation. (1997) (93)
- Semaphorin 4D regulates gonadotropin hormone–releasing hormone-1 neuronal migration through PlexinB1–Met complex (2008) (92)
- Different point mutations in the met oncogene elicit distinct biological properties (2000) (87)
- Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: from basic research to a clinical perspective. (2013) (80)
- Hepatocyte Growth Factor Is a Regulator of Monocyte-Macrophage Function1 (2001) (80)
- Activation of RAS family members confers resistance to ROS1 targeting drugs (2014) (80)
- Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis (1999) (79)
- TGFalpha expression impairs Trastuzumab-induced HER2 downregulation. (2005) (77)
- Yes‐associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice (2011) (76)
- Nrf2, but not β‐catenin, mutation represents an early event in rat hepatocarcinogenesis (2015) (75)
- Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression (2012) (73)
- p145, a protein with associated tyrosine kinase activity in a human gastric carcinoma cell line (1988) (73)
- Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis (2016) (71)
- Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene. (1992) (69)
- Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study (2017) (68)
- 3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors (2016) (65)
- Structural and functional domains critical for constitutive activation of the HGF-receptor (Met). (1994) (65)
- MicroRNA/gene profiling unveils early molecular changes and NRF2 activation in a rat model recapitulating human HCC. (2014) (65)
- TGFα expression impairs Trastuzumab-induced HER2 downregulation (2005) (65)
- Defective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor) (1991) (65)
- Targeted therapies for gastric cancer: failures and hopes from clinical trials (2017) (62)
- Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein. (1990) (60)
- Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats (2015) (60)
- YAP-Dependent AXL Overexpression Mediates Resistance to EGFR Inhibitors in NSCLC (2017) (59)
- Targeted therapies for gastric cancer: failures and hopes from clinical trials. (2017) (56)
- Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging (2016) (55)
- MET receptor is overexpressed but not mutated in oral squamous cell carcinomas (2001) (55)
- HER2-positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and are sensitive to the multitargeted kinase inhibitor sorafenib (2011) (54)
- How Can Gastric Cancer Molecular Profiling Guide Future Therapies? (2016) (53)
- Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response (2015) (52)
- Rilotumumab, a mAb against human hepatocyte growth factor for the treatment of cancer. (2009) (49)
- Structure and inducible regulation of the human MET promoter. (1994) (49)
- Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies (2018) (47)
- By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy (2014) (45)
- Microsatellite instability in Gastric Cancer: Between lights and shadows. (2021) (45)
- Control of invasive growth by the HGF receptor family (1997) (45)
- Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling (2001) (44)
- Targeting MET: why, where and how? (2013) (43)
- Shedding‐Generated Met Receptor Fragments can be Routed to Either the Proteasomal or the Lysosomal Degradation Pathway (2012) (43)
- Basic fibroblast growth factor expression is required for clonogenic growth of human glioma cells (1993) (42)
- Generation of a truncated hepatocyte growth factor receptor in the endoplasmic reticulum. (1994) (41)
- A comprehensive PDX gastric cancer collection captures cancer cell intrinsic transcriptional MSI traits. (2019) (39)
- Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction (2009) (36)
- Methylation analysis of the promoter F of estrogen receptor α gene: effects on the level of transcription on human osteoblastic cells (2004) (33)
- Resistance to targeted therapies: a role for microRNAs? (2013) (33)
- Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming. (2020) (31)
- Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor (2018) (31)
- Human ASH‐1 Promotes Neuroendocrine Differentiation in Androgen Deprivation Conditions and Interferes With Androgen Responsiveness in Prostate Cancer Cells (2013) (30)
- Expression of the human oestrogen receptor-alpha gene is regulated by promoter F in MG-63 osteoblastic cells. (2003) (28)
- The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival. (2016) (28)
- Induction of apoptosis of human primary osteoclasts treated with a transcription factor decoy mimicking a promoter region of estrogen receptor α (2005) (27)
- Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort (2017) (27)
- Clustered protocadherins methylation alterations in cancer (2019) (27)
- The c-met/HGF receptor in human tumours (1992) (26)
- Immunological detection of proteins phosphorylated at tyrosine in cells stimulated by growth factors or transformed by retroviral-oncogene-coded tyrosine kinases. (1986) (25)
- FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma. (2021) (25)
- Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis (2015) (25)
- miR‐205 mediates adaptive resistance to MET inhibition via ERRFI1 targeting and raised EGFR signaling (2018) (24)
- The landscape of d16HER2 splice variant expression across HER2-positive cancers (2019) (24)
- Electrostatic Intraperitoneal Aerosol Delivery of Nanoparticles: Proof of Concept and Preclinical Validation (2020) (24)
- Semaphorin pathways orchestrate osteogenesis (2006) (22)
- Expression of functional tyrosine kinases on immortalized Kaposi's sarcoma cells (2000) (22)
- Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies. (2018) (21)
- Proteins phosphorylated on tyrosine as markers of human tumor cell lines (1987) (21)
- Invasive growth: A two-way street for semaphorin signalling (2004) (21)
- BRAF and MEK Inhibitors Increase PD-1-Positive Melanoma Cells Leading to a Potential Lymphocyte-Independent Synergism with Anti–PD-1 Antibody (2018) (20)
- Co-occurring KRAS mutation/LKB1 loss in non-small cell lung cancer cells results in enhanced metabolic activity susceptible to caloric restriction: an in vitro integrated multilevel approach (2018) (20)
- ErbB2 and bone sialoprotein as markers for metastatic osteosarcoma cells (2003) (20)
- CD 100 / Plexin-B 1 interactions sustain proliferation and survival of normal and leukemic CD 5 B lymphocytes (2003) (18)
- Rapid automated diagnosis of primary hepatic tumour by mass spectrometry and artificial intelligence (2020) (17)
- Clinical Implications of DNA Repair Defects in High-Grade Serous Ovarian Carcinomas (2020) (17)
- Induction of apoptosis of human primary osteoclasts treated with a transcription factor decoy mimicking a promoter region of estrogen receptor alpha. (2005) (16)
- Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence (2014) (16)
- Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts12 (2018) (15)
- Application of 3D Mass Spectrometry Imaging to TKIs (2017) (15)
- Evidence for autocrine activation of a tyrosine kinase in a human gastric carcinoma cell line (1988) (14)
- A Nanostructured Matrices Assessment to Study Drug Distribution in Solid Tumor Tissues by Mass Spectrometry Imaging (2017) (13)
- Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2021) (12)
- Quantitative determination of niraparib and olaparib tumor distribution by mass spectrometry imaging (2020) (12)
- Nrf2 in Neoplastic and Non-Neoplastic Liver Diseases (2020) (12)
- Tyrosine kinases as molecular targets to inhibit cancer progression and metastasis. (2010) (11)
- Erratum: Only a subset of met-activated pathways are required to sustain oncogene addiction (Science Signaling (2009) 2 (er11) (2009) (11)
- Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis (2020) (11)
- Immune Check Point Inhibitors in Primary Cutaneous T-Cell Lymphomas: Biologic Rationale, Clinical Results and Future Perspectives (2021) (10)
- MiRNAs as new master players (2009) (10)
- C-met activation is necessary but not sufficient for liver colonization by B16 murine melanoma cells (1998) (10)
- Potential role of two novel agonists of thyroid hormone receptor‐β on liver regeneration (2020) (9)
- MicroRNAs: new tools for diagnosis, prognosis and therapy in HCC? (9)
- TRANSFER OF THE MOTOGENIC AND INVASIVE RESPONSE TO SCATTER FACTOR HEPATOCYTE GROWTH-FACTOR BY TRANSFECTION OF THE HUMAN C-MET PROTOONCOGENE (1993) (9)
- Transcription factor decoy against promoter C of estrogen receptor α gene induces a functional ERα protein in breast cancer cells (2005) (9)
- Differential requirement of the last C-terminal tail of Met receptor for cell transformation and invasiveness (2001) (9)
- Optimized EGFR Blockade Strategies in EGFR Addicted Gastroesophageal Adenocarcinomas (2021) (8)
- Patient-Derived Orthotopic Xenograft models in gastric cancer: a systematic review (2020) (8)
- Targeting Plasmodium host cells: survival within hepatocytes. (2004) (8)
- Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3. (2011) (8)
- A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine (2022) (7)
- Drug-Homogeneity Index in Mass-Spectrometry Imaging. (2018) (7)
- Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas (2022) (7)
- Past-in-the-Future. Peak detection improves targeted mass spectrometry imaging. (2018) (7)
- Molecularly Targeted Therapies for Gastric Cancer. State of the Art (2021) (7)
- Targeted therapies in cancer and mechanisms of resistance (2014) (6)
- Autocrine Signaling of NRP1 Ligand Galectin-1 Elicits Resistance to BRAF-Targeted Therapy in Melanoma Cells (2020) (6)
- MiR-100 is a predictor of endocrine responsiveness and prognosis in patients with operable luminal breast cancer (2020) (6)
- Amplification of the MET receptor to drive resistance to anti-EGFR therapies in colorectal cancer. (2013) (5)
- A methodological approach to correlate tumor heterogeneity with drug distribution profile in mass spectrometry imaging data (2020) (5)
- A long term, non-tumorigenic rat hepatocyte cell line and its malignant counterpart, as tools to study hepatocarcinogenesis (2017) (5)
- Transcription factor decoy against promoter C of estrogen receptor alpha gene induces a functional ER alpha protein in breast cancer cells. (2005) (5)
- Chest wall infiltration is a critical prognostic factor in breast implant-associated anaplastic large-cell lymphoma affected patients. (2021) (4)
- The importance of being CAFs (in cancer resistance to targeted therapies) (2022) (3)
- Non-linear relationship between HER-2 expression and response to trastuzumab in breast cancer cells. (2006) (3)
- Personalized therapeutic strategies in HER2-driven gastric cancer (2021) (2)
- APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett’s-associated esophageal adenocarcinomas (2022) (2)
- Editorial: Metabolism As a Therapeutic Target (2017) (2)
- [Malignant mesothelioma of the pleura in a worker with brief atypical exposure to chrysotile asbestos]. (2004) (2)
- Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC (2021) (2)
- The metabolic gene HAO2 is downregulated in mouse, rat and human hepatocellular carcinoma and correlates with metastasis and poor survival (2016) (2)
- Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2021) (2)
- Mutations of Nrf2 are an early and frequent event in the development of rat hepatocellular carcinoma (2015) (2)
- hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers (2022) (2)
- Diverse MicroRNAs‐mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia (2022) (1)
- Preclinical activity of two paclitaxel nanoparticle formulations after IP administration in ovarian cancer xenografts (2018) (1)
- A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer (2021) (1)
- Signaling from Internalized Receptors (2006) (1)
- Correction: By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy (2019) (1)
- The Tyrosine Kinase c-Met Is Selectively Expressed on Motile Hematopoietic Progenitors Following G-CSF Administration and Promotes Mobilization by Regulating Stem Cell Niche Components. (2006) (1)
- FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signaling (2020) (1)
- Reply to: "YAP in tumorigenesis: Friend or foe?". (2015) (1)
- A chimeric antibody (MV-DN30) inhibiting (2014) (1)
- Extensive “halo naevi” phenomenon and regression of melanin during nivolumab treatment in metastatic melanoma: A predictor of a better outcome? (2022) (1)
- Abstract 1009: Metabolic reprogramming discriminates aggressive vs. slowly growing preneoplastic lesions at early stages of HCC development (2016) (1)
- Researchof HER family members in gastric carcinoma cells mediates resistance to MET inhibition (2010) (1)
- Efficacy of CAR-T immunotherapy in MET overexpressing tumors not eligible for anti-MET targeted therapy (2022) (1)
- Potential role of two novel agonists of thyroid hormone receptor-beta on liver regeneration (2020) (1)
- Reviewmechanisms of acquired resistance to tyrosine kinase targeted therapy (2010) (1)
- Correction: hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers (2022) (0)
- Abstract B12: Understanding the role of the tumor microenvironment in mediating resistance to anti-MET drugs (2015) (0)
- Combined anti-MET/EGFR treatment results in complete tumor regression and prevents resistance onset in a MET-amplified gastroesophageal xenopatient cohort (2016) (0)
- Abstract A82: HHER2‐positive breast cancer cells resistant to trastuzumab and lapatinib lose reliance upon HER2 and become sensitive to the multitargeted kinase inhibitor sorafenib (2009) (0)
- Identification and Localization of Phosphoproteins in v-onc Transformed Fibroblasts by Means of Phosphotyrosine Antibodies (1985) (0)
- The HGF/SF receptor kinase: structure and function (1993) (0)
- Proteins phosphorylated on tyrosine as markers of human malignancies (1987) (0)
- 216 MIR-100 IS DOWNREGULATED FROM EARLY STAGES OF HEPATOCARCINOGENESIS AND CORRELATES WITH OVEREXPRESSION OF ITS TARGET PLK1 (2011) (0)
- Nanoparticle-based matrixes for imaging mass spectrometry: visualization of drugs distribution in solid tumor tissues (2015) (0)
- APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett’s-associated esophageal adenocarcinomas (2022) (0)
- Abstract P1-09-21: Clinical evaluation of miR-100 as a predictor of endocrine-responsiveness in hormone-receptor positive breast cancer (2017) (0)
- Abstract 3851: Targeting HER2 in gastric cancer: Hints from a gastric PDX platform (2017) (0)
- Hepatocyte growth factor/met system (2003) (0)
- Ciclo XXVII ROLE OF HYDROXY ACID OXIDASE 2 ( HAO 2 ) (2015) (0)
- Abstract 1399: NRF2 mutations are frequent in early rat preneoplastic hepatic lesions and in human hepatocellular carcinomas positive for the stem/progenitor cell marker KRT-19 (2014) (0)
- 312 MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors (2010) (0)
- Identification of a subpopulation of patients with gastric cancer responsive to PARP inhibitors. (2023) (0)
- Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas (2022) (0)
- 455 HER2: A target for prostate cancer therapy? (2004) (0)
- P59 YES-ASSOCIATED PROTEIN (YAP) IS REQUIRED FOR THE CLONAL EXPANSION OF PRENEOPLASTIC HEPATOCYTES AND OVAL CELL PROLIFERATION (2014) (0)
- Interdisciplinar and multidimensional approach in neoplastic aged patients (1997) (0)
- Metabolic Reprogramming toward Awarburg Phenotype Characterizes Early Phases of Hepatic Carcinogenesis (2016) (0)
- 234 ROLE OF YAP IN THE REGULATION OF XENOBIOTIC-INDUCED LIVER ENLARGEMENT AND HCC DEVELOPMENT (2011) (0)
- Monocyte-Macrophage Function Hepatocyte Growth Factor Is a Regulator of (2000) (0)
- The Tumor-Specific Expression of L1 Retrotransposons Independently Correlates with Time to Relapse in Hormone-Negative Breast Cancer Patients (2022) (0)
- Author Correction: The landscape of d16HER2 splice variant expression across HER2-positive cancers (2020) (0)
- Transcription profiling by array of mouse liver from TCPOBOP treated wild type and c-jun conditional knockout animals. (2012) (0)
- Molecular Classification of Gastric Cancer: A New Perspective for Therapy and Prognosis? (2021) (0)
- Correction: hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers (2022) (0)
- Abstract A04: Combined anti–MET/EGFR treatment results in complete tumor regression and prevents resistance onset in a MET-amplified gastroesophageal xenopatient cohort (2016) (0)
- Abstract 622: Gastric cancer in the age of targeted agents: identification and validation of novel therapeutic strategies through the generation of a patient-derived xenografts platform (2016) (0)
- 671: Inhibition of angiogenesis promotes a homogeneous intra-tumor distribution of chemotherapy associated with better antitumor response (2014) (0)
- A nanostructured matrices assessement to study drugs distribution in solid tumor tissues by mass spectrometry imaging (2015) (0)
- normal and leukemic CD5+ B lymphocytes CD100/Plexin-B1 interactions sustain proliferation and survival of (2013) (0)
- Detection of deregulated tyrosine-kinases in experimental and human metastatic tumors. (1988) (0)
- hOA-DN30: a highly effective humanized single-arm MET antibody inducing remission of ‘MET-addicted’ cancers (2022) (0)
- hematopoietic progenitor cells via ROS signaling induced mobilization of - Enhanced c-Met activity promotes G-CSF (2011) (0)
- P0397 : Nrf2 mutations are an early and frequent event in the development of rat hepatocellular carcinoma (2015) (0)
- Stem Cells Tumorigenic and Metastatic Activity of Human Thyroid Cancer (2010) (0)
- Cancer esearch apeutics , Targets , and Chemical Biology T and KRAS Gene Amplification Mediates Acquired R istance to MET Tyrosine Kinase Inhibitors (2010) (0)
- 65 MET, the HGF receptor: Possible role in prostate cancer metastatization (2005) (0)
- HER2 Copy Number and Resistance Mechanisms in Patients with HER2-positive Advanced Gastric Cancer Receiving Initial Trastuzumab-based Therapy in JACOB Trial (2022) (0)
- High resolution AP-MALDI MS imaging as an aid to develop new strategies to improve ALS therapy (2017) (0)
- Drugs distribution assessment in solid tumor tissues : an advanced Imaging Mass Spectrometry analysis (2016) (0)
- Human Cancer Biology MiR-1 DownregulationCooperateswithMACC 1 inPromoting MET Overexpression in Human Colon Cancer (2012) (0)
- Abstract 3606: Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence (2015) (0)
- Intro The lignan plastic inhibi (2010) (0)
- Structure, Biosynthesis and Biochemical Properties of the HGF/SF Receptor (1993) (0)
- Abstract A02: OXPHOS inhibition and pentose phosphate pathway induction are early events priming preneoplastic lesions toward HCC development (2016) (0)
- [Pleural malignant mesothelioma in a barber: a case of atypical and indirect professional exposure to asbestos]. (2005) (0)
- Co-occurring KRAS mutation/LKB1 loss in non-small cell lung cancer cells results in enhanced metabolic activity susceptible to caloric restriction: an in vitro integrated multilevel approach (2018) (0)
- Oncogenes and tumor suppressor genes (2020) (0)
- In-home supportive therapy and LD-ARA-C for high risk acute leukemic elderly patients (1994) (0)
- Mechanisms of Resistance to Molecular Therapies Targeting the HGF/MET Axis (2018) (0)
- Home-care treatment for selected acute leukemic elderly patients by low dose ARA-C (1993) (0)
- Altered regulation of receptor associated-tyrosine kinases in human tumors (1989) (0)
- Author Correction: The landscape of d16HER2 splice variant expression across HER2-positive cancers (2020) (0)
- Validation of a model of orthotopic transplantation of human gastric cancer in NOD SCID mice for generation of a gastro-esophageal patient-derived xenograft (PDX) platform to improve therapeutic outcome (2018) (0)
- Clustered protocadherins methylation alterations in cancer (2019) (0)
- Deregulated tyrosine kinases detected in human tumors by means of antibodies against phosphotyrosine (1989) (0)
- P0317 : Down-regulation of Hao2 is associated with the onset and development of hepatocellular carcinoma in rodents (2015) (0)
- 881 Could antineoplastic therapy integrate palliative care for symptom relief in advanced/refractory cancer patients? (1995) (0)
- The landscape of d16HER2 splice variant expression across HER2-positive cancers (2019) (0)
- Reply (2011) (0)
- CAN-10-1994 Cancer esearch or and Stem Cell Biology origenic and Metastatic Activity of Human Thyroid R cer Stem Cells (2010) (0)
- Targeted therapies in cancer and mechanisms of resistance (2014) (0)
- Fatty acid synthase as a new therapeutic target for HER2-positive gastric cancer. (2023) (0)
- mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma (2022) (0)
- origenic and Metastatic Activity of Human Thyroid (2010) (0)
- Growth Factor Receptor (2020) (0)
- BRCA2 Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors. (2023) (0)
- Abstract 5603: Melanoma PD1 expression is upregulated by MAPK inhibitors leading to an immune-independent synergism with anti-PD1 antibodies (2017) (0)
- miRs*: Innocent bystanders only? (2016) (0)
- Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System (2022) (0)
- Local hypothyroidism favours the progression of rat preneoplastic lesions to HCC (0)
- HGF (Hepatocyte Growth Factor)/MET System (2003) (0)
- microRNAは肝細胞癌の診断,予後予測,治療の新たなツールとなるか? (2013) (0)
- Proteins phosphorylated at tyrosine residues in cells transformed by v-onc genes (1984) (0)
- IMMUNOLOGICAL DETECTION OF CELLULAR TARGETS FOR V-ONC GENE CODED (1984) (0)
- Abstract C92: MET amplification and overexpression sustain resistance and drive drug dependency to the DN30Fab antibody in MET-addicted cells. (2013) (0)
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Silvia Giordano is affiliated with the following schools: