Simon Benita
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Biology
Simon Benita's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Simon Benita's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nanocapsule formation by interfacial polymer deposition following solvent displacement (1989) (1916)
- Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. (2004) (1226)
- Microencapsulation : methods and industrial applications (1996) (640)
- Targeting of nanoparticles to the clathrin-mediated endocytic pathway. (2007) (517)
- Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs. (2000) (490)
- Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells. (2008) (376)
- Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization. (1993) (298)
- A new in vitro technique for the evaluation of drug release profile from colloidal carriers - ultrafiltration technique at low pressure (1993) (261)
- Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles. (2000) (255)
- Successfully Improving Ocular Drug Delivery Using the Cationic Nanoemulsion, Novasorb (2012) (236)
- Drug release from submicronized o/w emulsion: a new in vitro kinetic evaluation model (1990) (193)
- Characterization of drug-loaded poly(d,l-lactide) microspheres. (1984) (183)
- Enhanced Oral Absorption of Paclitaxel in a Novel Self-Microemulsifying Drug Delivery System with or Without Concomitant Use of P-Glycoprotein Inhibitors (2004) (156)
- The potential of lipid emulsion for ocular delivery of lipophilic drugs. (2004) (148)
- Positively and negatively charged submicron emulsions for enhanced topical delivery of antifungal drugs. (1999) (146)
- Positively charged self-emulsifying oil formulation for improving oral bioavailability of progesterone. (1996) (133)
- Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts (2017) (125)
- Submicron Emulsions in Drug Targeting and Delivery (2019) (119)
- Interaction of a Self-Emulsifying Lipid Drug Delivery System with the Everted Rat Intestinal Mucosa as a Function of Droplet Size and Surface Charge (1998) (113)
- Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption (2013) (113)
- Nanoparticle characterization : a comprehensive physicochemical approach (1991) (112)
- Analysis for Policy: Evidence-Based Policy in Practice (2007) (102)
- Antibody conjugated PLGA nanoparticles for targeted delivery of paclitaxel palmitate: efficacy and biofate in a lung cancer mouse model. (2013) (102)
- POLYACRYLATE (EUDRAGIT RETARD) MICROSPHERES FOR ORAL CONTROOED RELEASE OF NIFEDIPINE. I. FORMULATION DESIGN AND PROCESS OPTIMIZATION (1990) (101)
- Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug. (2009) (97)
- Excipient effects on in vitro cytotoxicity of a novel paclitaxel self-emulsifying drug delivery system. (2003) (95)
- Design and characterization of a submicronized o/w emulsion of diazepam for parenteral use (1989) (85)
- Characterization of diazepam submicron emulsion interface: role of oleic acid. (1994) (84)
- A submicron emulsion as ocular vehicle for delta-8-tetrahydrocannabinol: effect on intraocular pressure in rabbits. (1992) (81)
- Investigation of the role of macrophages on the cytotoxicity of doxorubicin and doxorubicin-loaded nanoparticles on M5076 cells in vitro. (2000) (81)
- Charge-dependent interaction of self-emulsifying oil formulations with Caco-2 cells monolayers: binding, effects on barrier function and cytotoxicity. (2000) (80)
- Ability of Doxorubicin-Loaded Nanoparticles to Overcome Multidrug Resistance of Tumor Cells After Their Capture by Macrophages (1999) (78)
- The influence of process parameters on the PLA nanoparticle size distribution, evaluated by means of factorial design (1995) (78)
- A safety and tolerability study of differently-charged nanoparticles for local pulmonary drug delivery. (2010) (77)
- The ligand nanoparticle conjugation approach for targeted cancer therapy. (2012) (73)
- Microencapsulation : Methods and Industrial Applications, Second Edition (2005) (71)
- Physicochemical Characterization and Acute Toxicity Evaluation of a Positively‐charged Submicron Emulsion Vehicle (1994) (71)
- Enhanced absorption and drug targeting by positively charged submicron emulsions (2000) (67)
- Release kinetics of sparingly soluble drugs from ethyl cellulose‐walled microcapsules: theophylline microcapsules (1982) (67)
- Pilocarpine incorporated into a submicron emulsion vehicle causes an unexpectedly prolonged ocular hypotensive effect in rabbits. (1994) (66)
- Nanoparticle-cell interactions: drug delivery implications. (2008) (65)
- In vitro release kinetic pattern of indomethacin from poly(D,L-lactide) nanocapsules. (1990) (64)
- Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye. (2010) (63)
- Fundamentals of release mechanism interpretation in multiparticulate systems: determination of substrate release from single microcapsules and relation between individual and ensemble release kinetics (1986) (61)
- Extensive surface studies help to analyse zeta potential data: the case of cationic emulsions. (2004) (59)
- Ex-vivo permeation study of indomethacin from a submicron emulsion through albino rabbit cornea (1997) (59)
- Cationic submicron emulsions for pulmonary DNA immunization. (2004) (58)
- Submicron Cationic Emulsions as a New Delivery System for Oligonucleotides (2004) (57)
- Interactions of a non-ionic ABA copolymer surfactant with phospholipid monolayers: Possible relevance to emulsion stabilization (1991) (57)
- Effect of polyisobutylene on ethyl cellulose-walled microcapsules: wall structure and thickness of salicylamide and theophylline microcapsules. (1982) (55)
- A Lipophilic Pt(IV) Oxaliplatin Derivative Enhances Antitumor Activity. (2016) (51)
- Anti-HER2 cationic immunoemulsion as a potential targeted drug delivery system for the treatment of prostate cancer. (2007) (49)
- Ocular delivery of cyclosporin A. II. Effect of submicron emulsion's surface charge on ocular distribution of topical cyclosporin A (2001) (47)
- Radiopaque liposomes: effect of formulation conditions on encapsulation efficiency. (1984) (47)
- Ocular antisense oligonucleotide delivery by cationic nanoemulsion for improved treatment of ocular neovascularization: an in-vivo study in rats and mice. (2012) (46)
- Fundamentals of release mechanism interpretation in multiparticulate systems: the prediction of the commonly observed release equations from statistical population models for particle ensembles (1986) (46)
- Positively charged submicron emulsions — a new type of colloidal drug carrier (1993) (46)
- Microencapsulation of paracetamol using polyacrylate resins (Eudragit Retard), kinetics of drug release and evaluation of kinetic model (1985) (45)
- Physostigmine emulsion: a new injectable controlled release delivery system (1986) (44)
- Effect of drug loading extent on the in vitro release kinetic behaviour of nifedipine from polyacrylate microspheres (1990) (44)
- Jejunal Absorption, Pharmacological Activity, and Pharmacokinetic Evaluation of Indomethacin-Loaded Poly(d,l-Lactide) and Poly(Isobutyl-Cyanoacrylate) Nanocapsules in Rats (2004) (43)
- Spinal anesthesia: significant prolongation of the pharmacologic effect of tetracaine with lipid solution of the agent. (1991) (42)
- Dissolution rate control of the release kinetics of water-soluble compounds from ethyl cellulose film-type microcapsules (1982) (42)
- The influence of cationic lipid type on in-vitro release kinetic profiles of antisense oligonucleotide from cationic nanoemulsions. (2008) (42)
- A Rabbit Model for Evaluation of Spinal Anesthesia: Chronic Cannulation of the Subarachnoid Space (1990) (41)
- Overcoming the formulation obstacles towards targeted chemotherapy: in vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles. (2008) (41)
- 5-Fluorouracil:carnauba wax microspheres for chemoembolization: an in vitro evaluation. (1986) (39)
- Improved oral absorption of exenatide using an original nanoencapsulation and microencapsulation approach. (2015) (39)
- High plasma levels and effective lymphatic uptake of docetaxel in an orally available nanotransporter formulation. (2011) (38)
- A submicron emulsion of HU-211, a synthetic cannabinoid, reduces intraocular pressure in rabbits (2000) (38)
- Design and release kinetic pattern evaluation of indomethacin microspheres intended for oral administration. (1988) (38)
- Evaluation of a positively charged submicron emulsion of piroxicam on the rabbit corneum healing process following alkali burn. (1999) (37)
- In vitro adsorption of plasma proteins onto the surface (charges) modified-submicron emulsions for intravenous administration. (2005) (37)
- Interactions of a non-ionic surfactant with mixed phospholipid—oleic acid monolayers. Studies under dynamic conditions (1991) (37)
- An in vitro release kinetic examination and comparative evaluation between submicron emulsion and polylactic acid nanocapsules of clofibride. (1995) (36)
- A Novel Nanocapsule Delivery System to Overcome Intestinal Degradation and Drug Transport Limited Absorption of P-glycoprotein Substrate Drugs (2008) (34)
- The stability and in vitro release kinetics of a clofibride emulsion (1991) (33)
- The stability of piroxicam incorporated in a positively-charged submicron emulsion for ocular administration (1996) (33)
- Prevention of topical and ocular oxidative stress by positively charged submicron emulsion. (1999) (32)
- Pilocarpine hydrochloride liposomes: characterization in vitro and preliminary evaluation in vivo in rabbit eye. (1984) (32)
- The design and evaluation of a novel targeted drug delivery system using cationic emulsion-antibody conjugates. (2005) (31)
- Binding mechanism of doxorubicin in ion-exchange albumin microcapsules. (1987) (31)
- A Mathematical Morel for Drug Release from 0/W Emulsions: Application to Controlled Release Morphine Emulsions (1987) (30)
- Permeability and mechanical properties of a new polymer: cellulose hydrogen phthalate (1986) (30)
- Surface properties of mixed phospholipid—stearylamine monolayers and their interaction with a non-ionic surfactant (poloxamer) (1994) (29)
- Factors influencing the oligonucleotides release from O-W submicron cationic emulsions. (2001) (29)
- Nystatin—dextran conjugates: Synthesis and characterization (1996) (28)
- Sequential statistical optimization of a positively-charged submicron emulsion of miconazole. (1996) (26)
- A quantitative evaluation of the molecular binding affinity between a monoclonal antibody conjugated to a nanoparticle and an antigen by surface plasmon resonance. (2010) (26)
- Direct measurements on individual microcapsule dissolution as a tool for determination of release mechanism (1986) (26)
- Pharmacokinetic evaluation of indomethacin nanocapsules. (1989) (24)
- Characterization of oligonucleotide/lipid interactions in submicron cationic emulsions: influence of the cationic lipid structure and the presence of PEG-lipids. (2001) (23)
- Solid nano‐in‐nanoparticles for potential delivery of siRNA (2017) (23)
- In vitro release and intestinal absorption of physostigmine salicylate from submicron emulsions. (1991) (21)
- Coacervation of ethyl cellulose: The role of polyisobutylene and the effect of its concentration (1980) (21)
- Emulsions as drug carriers for ophthalmic use (1994) (21)
- New Bicompartmental Structures Are Observed When Stearylamine is Mixed with Triglyceride Emulsions (2000) (20)
- Influence of oil droplet surface charge on the performance of antibody--emulsion conjugates. (2007) (20)
- Penetration of poly(oxyethylene)—poly (oxypropylene) block copolymer surfactant into soya phospholipid monolayers (1991) (20)
- Ocular delivery of cyclosporin A. I. Design and characterization of cyclosporin A-loaded positively-charged submicron emulsion (2001) (20)
- Polyacrylate resin (Eudragit retard) microcapsules as a controlled release drug delivery system-improved non-solvent addition phase separation process. (1985) (20)
- Controlled release of radioprotective agents from matrix tablets—effect of preparative conditions on release rates (1984) (19)
- Prevention of oxidative damage in fibroblast cell cultures and rat skin by positively-charged submicron emulsion of α-tocopherol (1996) (18)
- THE EFFECT OF POLYISOBUTYLENE ON THE COACERVATION OF ETHYL CELLULOSE AND THE FORMATION OF MICROCAPSULES (1977) (18)
- Self-Emulsifying Oral Lipid-Based Formulations for Improved Delivery of Lipophilic Drugs (2005) (18)
- The design and characterization of a positively charged submicron emulsion containing a sunscreen agent (1994) (18)
- Cationic emulsions improves the delivery of oligonucleotides to leukemic P388/ADR cells in ascite. (2003) (17)
- Non-systemic delivery of topical brimonidine to the brain: A neuro-ocular tissue distribution study (2006) (16)
- Bio-Imaging of Colorectal Cancer Models Using Near Infrared Labeled Epidermal Growth Factor (2012) (16)
- Kinetic model identification of drug release from microcapsules using the nonlinear regression search procedure. (1984) (16)
- Side-Effect Evaluation of a New Diazepam Formulation: Venous Sequela Reduction Following Intravenous (iv) Injection of a Diazepam Emulsion in Rabbits (1989) (16)
- Phase separation modulation and aggregation prevention: mechanism of the non-solvent addition method in the presence and absence of polyisobutylene as an additive. (1990) (16)
- Topical tacrolimus νanocapsules eye drops for therapeutic effect enhancement in both anterior and posterior ocular inflammation models. (2021) (15)
- Ion-exchange albumin microcapsules of doxorubicin: an in vitro release kinetic evaluation. (1988) (15)
- The characterization and release kinetics evaluation of baclofen microspheres designed for intrathecal injection. (1999) (15)
- Efficacy evaluation of a novel submicron amphotericin B emulsion in murine candidiasis. (1993) (14)
- Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications (2012) (14)
- Safety and proof-of-concept efficacy of inhaled drug loaded nano- and immunonanoparticles in a c-Raf transgenic lung cancer model. (2012) (14)
- Prolongation of the Pharmacologic Effect of Intrathecal Meperidine by the Use of a Lipid Solution of It (1991) (14)
- Microcapsules: new applications and characterization (1984) (14)
- Topical NANO-encapsulated cyclosporine formulation for atopic dermatitis treatment. (2019) (14)
- Biodegradable cross-linked albumin microcapsules for embolization. (1984) (13)
- Enhanced cutaneous bioavailability of dehydroepiandrosterone mediated by nano-encapsulation. (2014) (13)
- Poly-lactic-glycolic Acid Microspheres: A Biodegradable Marker for the Diagnosis of Aspiration in Hamsters (2005) (12)
- Efficacy of a novel pH‐buffering tampon in preserving the acidic vaginal pH during menstruation (2004) (11)
- Efficacy Evaluation of a Novel Submicron Miconazole Emulsion in a Murine Cryptococcosis Model (1995) (11)
- Design and characterization of protein-based microcapsules as a novel catamenial absorbent system. (2002) (11)
- Drug-loaded nanocarriers for back-of-the-eye diseases- formulation limitations (2015) (11)
- Relation Between Individual and Ensemble Release Kinetics of Indomethacin from Microspheres (1988) (11)
- Enhanced stability of physostigmine salicylate in submicron o/w emulsion (1990) (10)
- Discrepancy between the development of tolerance to bupivacaine in extradural and spinal anaesthesia in rabbits. (1993) (9)
- Short- and long-term stability assessment of a new injectable diazepam submicron emulsion. (1991) (8)
- Duration of spinal anaesthesia is determined by the partition coefficient of local anaesthetic. (1994) (8)
- Microencapsulation of dichromate and paracetamol with Eudragit Retard polymers using phase separation by nonsolvent addition (1984) (8)
- Pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro‐resistant microparticles (2018) (8)
- COSMETIC APPLICATIONS OF VESICULAR DELIVERY SYSTEMS (1996) (8)
- A RABBIT MODEL FOR EVALUATION OF SPINAL ANESTHESIA (1989) (7)
- Release kinetics of sparingly soluble drugs from ethyl cellulose‐walled microcapsules: salicylamide microcapsules (1982) (7)
- Recent Advances and Industrial Applications of Microencapsulation (1998) (6)
- Intravenous fat emulsion: effect of process parameters on the properties of a new intravenous fat emulsion (1989) (6)
- Dermal absorption behavior of fluorescent molecules in nanoparticles on human and porcine skin models. (2017) (5)
- Drug Delivery Systems for Enhanced Ocular Absorption (2006) (5)
- Nanocapsules embedded in microparticles for enhanced oral bioavailability and efficacy of Lopinavir as an anti-AIDS drug (2019) (4)
- Micronized emulsion for controlled release of physostigmine after oral administration. Part II. Release characteristics and pharmacological evaluation. (1989) (4)
- Towards a new galenic dosage form, the liposomes? (1982) (4)
- Cellulose hydrogen phthalate. A coating polymer in controlled release dosage forms. (1987) (4)
- The dose-dependent effect of a stabilized cannabidiol nanoemulsion on ocular surface inflammation and intraocular pressure. (2022) (4)
- Manufacture, Characterization, and Applications of Solid Lipid Nanoparticles as Drug Delivery Systems (2005) (4)
- Advances in the Technology for Controlled-Release Pesticide Formulations (2005) (4)
- Gradation of microcapsule wall porosity by deposition of polymer mixtures (Eudragit RL and Eudragit RS). Phase separation of polymer mixtures and effects of external media and conditions on release. (1995) (4)
- Penetration of amphoteric surfactants into phospholipid monolayers spread at the air-water interface (1993) (3)
- Cosmetic Applications of Colloidal Delivery Systems (2005) (3)
- Kinetic model identification of drug release from microcapsules using the nonlinear regression search procedure (1984) (3)
- The use of factorial design in the development of nanoparticulate dosage forms (1996) (3)
- The effect of oil nature in o/w submicron emulsion on the oral absorption profile of physostigmine salicylate in rats (1993) (3)
- Lipid and Polymeric Colloidal Carriers for Ocular Drug Delivery (2005) (2)
- Materials for Nanoemulsions and Their Influence on the Biofate (2020) (2)
- Biodistribution and efficacy of the anticancer drug, oxaliplatin palmitate acetate, in mice. (2021) (2)
- Vesicles as a Tool for Dermal and Transdermal Delivery (2005) (2)
- Study of Formulation Parameters Effect on Interfacial Interactions of Topically Instilled Eye Drops With the Ocular Surface by Dynamic and Static Methods: Implication for Tear Substitutes Wettability (2006) (1)
- Drug Release from Microparticulate Systems (2005) (1)
- Micronized emulsion for controlled release of physostigmine after oral administration. Part I. Formulation design. (1989) (1)
- Interfacial Interactions Of Cationic And Anionic Artificial Tears With Ionic Hydrogel Contact Lens Surface (2012) (1)
- Ocular and Regional Tissue Distribution of Topically Applied Ocular Therapeutics Part A: How Does a Topically Applied Drug Penetrate to the Back of the Eye? (2003) (1)
- TOLERANCE TO SPINAL ANESTHESIA: DOES IT REALLY EXIST? (1989) (1)
- Paclitaxel palmitate-loaded anti-HER2 cationic immunoemulsion: pharmacokinetic and biodistribution study in healthy mice (2009) (1)
- THE DESIGN AND IN VITRO RELEASE CHARACTERIZATION OF HUMAN CROSS-LINKED HAEMOSLDBIN MICROCAPSULES CONTAINING DOXORUBICIN FOR POTENTIAL CHEMOEMBOLIZATION USE (1989) (1)
- POLYACRYLATE (Eudragit Retard) MICROSPHERES FOR ORP..L CONTROLLED RELEASE OF IIIFEDIPINE. I. FORMULATION DESIGN AKD (1990) (1)
- Intravitreous Injection of VEGF-R2antisense Oligonucleotides Limits the Growth of Retinal New Vessels in the Mouse Rop Model (2008) (1)
- Economics of coconut products A study in Coimbatore district (2010) (1)
- Formulation for slow release of oral radiation-protection drugs. (1984) (1)
- Ocular and Regional Tissue Distribution of Topically Applied Ocular Therapeutics Part B: Non-Systemic Delivery of Topical Brimonidine to the Brain (2003) (1)
- Efficacy of Sustained-Release Radioprotective Drugs in vivo (1987) (1)
- [Colloid drug delivery systems: a response to therapeutic expectations arising from biotechnological advances?]. (2005) (1)
- Pharmaceutical Aspects of Liposomes: Academic and Industrial Research and Development (2005) (0)
- Self-emulsifiable formulation to form an oil-in-water emulsion (1994) (0)
- Pharmaceutical composition of hydrophobic medicinal agent in form of oil in water emulsion (1990) (0)
- Biodegradable microcapsules has basic serum albumin, their preparation and their application to the release in situ of medicuments (1984) (0)
- Composition for eye (1992) (0)
- SUSTAINED RELEASE OF RADIOPROTECTIVE AGENTS IN VITRO (1980) (0)
- Novel high-content paclitaxel palmitate nanospheres for improved cancer treatment (2009) (0)
- Self-emulsifying systems for relief of taxoids (2003) (0)
- Amphiphilic Cyclodextrins and Microencapsulation (2005) (0)
- STEALTH NANOCAPSULES ENHANCE INTESTINAL ABSORPTION OF LIPOPHILIC P-GLYCOPROTEIN SUBSTRATE DRUGS (2008) (0)
- Industrial Technologies and Scale-Up (2005) (0)
- Erratum to “Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye” [J. Control. Release 145 (3) (2010 Aug 3) 297–305] (2011) (0)
- [Oral emulsions: preparation and bioavailability]. (1993) (0)
- The Design and Evaluation of a Novel Submicron Amphotericin B Emulsion in Systemic Murine Cryptococcosis (1996) (0)
- A NOVEL APPROACH FOR A SIGNIFICANT PROLONGATION OF SPINAL ANESTHESIA (1989) (0)
- Self-nanoemulgierende oily formulation for the administration of poorly water-soluble pharmaceuticals (2004) (0)
- A method and composition for the treatment of dry eye (2001) (0)
- Microspheres with nano capsules that contain a lipophilic drug (2007) (0)
- Auto-nanoemulsifying oleaginous formulation for the administration of poorly water-soluble drugs. (2004) (0)
- Emulsions pharmaceutical or cosmetic oil in water positively charged particles. (1993) (0)
- Immunonanoparticles for Nuclear Imaging and Radiotherapy (2012) (0)
- A process for the preparation of biodegradable microcapsules based on serum albumin. (1985) (0)
- Erratum (2007) (0)
- INTRATHECAL OPIATES: A NEW WAY FOR PROLONGATION OF PHARMACOLOGICAL EFFECT (1989) (0)
- Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma (2020) (0)
- [Frontiers in Bioscience 10, 1440-1461 May 1, 2005] 1440 ESTROGEN RECEPTOR REGULATION OF QUINONE REDUCTASE IN BREAST CANCER: IMPLICATIONS FOR ESTROGEN-INDUCED BREAST TUMOR GROWTH AND THE THERAPEUTIC USES OF TAMOXIFEN (2005) (0)
- Intravenous Fat Emulsion (1989) (0)
- Microspheres de diagnostic (2003) (0)
- Minit-Livin Conjugated to Targeted Nanoparticles Inhibits Tumorigenicity (2018) (0)
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