Simon Lovestone
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Simon Lovestonebiology Degrees
Biology
#5164
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#7581
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Neuroscience
#573
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#598
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Molecular Biology
#673
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#690
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Biology
Simon Lovestone's Degrees
- PhD Neuroscience University of Oxford
Why Is Simon Lovestone Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Simon Lovestone is professor of translational neuroscience at the University of Oxford. He is a specialist in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. He was made a knight bachelor in the 2017 Queen's Birthday Honours for services to neuroscience research.
Simon Lovestone's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2013) (3484)
- Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. (1996) (2280)
- Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) (1996) (2138)
- Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease (2011) (1701)
- Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease (2009) (1644)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes (2009) (1441)
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2013) (1388)
- Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease (2014) (1230)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (1073)
- The GSK3 hypothesis of Alzheimer's disease (2008) (992)
- Common genetic variants influence human subcortical brain structures (2015) (731)
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (2017) (693)
- Head injury as a risk factor for Alzheimer’s disease: the evidence 10 years on; a partial replication (2003) (668)
- Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood (2012) (619)
- Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease (2010) (587)
- Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. (2008) (522)
- Alzheimer's disease – do tauists and baptists finally shake hands? (2002) (512)
- Is MCI really just early dementia? A systematic review of conversion studies (2004) (469)
- Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells (1994) (462)
- Susceptibility locus for Alzheimer's disease on chromosome 10. (2000) (397)
- Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. (2010) (385)
- The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data (2009) (385)
- A full genome scan for late onset Alzheimer's disease (1999) (383)
- Proteome-based plasma biomarkers for Alzheimer's disease. (2006) (380)
- Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease (2014) (343)
- Glycogen synthase kinase‐3 inhibition is integral to long‐term potentiation (2007) (332)
- A phase II trial of tideglusib in Alzheimer's disease. (2015) (316)
- The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes. (1997) (308)
- Common variants at ABCA 7 , MS 4 A 6 A / MS 4 A 4 E , EPHA 1 , CD 33 and CD 2 AP are associated with Alzheimer ’ s disease (2011) (292)
- Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. (2015) (285)
- The Importance of Tau Phosphorylation for Neurodegenerative Diseases (2013) (281)
- Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. (2007) (271)
- Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease (1999) (267)
- The future of blood-based biomarkers for Alzheimer's disease (2014) (265)
- Novel genetic loci associated with hippocampal volume (2017) (238)
- Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease (2014) (234)
- Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness☆ (2014) (225)
- Common brain disorders are associated with heritable patterns of apparent aging of the brain (2019) (213)
- The C9ORF72 expansion mutation is a common cause of ALS+/−FTD in Europe and has a single founder (2012) (213)
- Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment (2011) (212)
- Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions (2015) (211)
- Full genome screen for Alzheimer disease: stage II analysis. (2002) (209)
- Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation (1999) (208)
- Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. (2012) (208)
- Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research (2015) (205)
- Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway (2012) (204)
- AddNeuroMed—The European Collaboration for the Discovery of Novel Biomarkers for Alzheimer's Disease (2009) (203)
- Plasma proteins predict conversion to dementia from prodromal disease (2014) (201)
- Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules (1996) (200)
- Do antidepressants regulate how cortisol affects the brain? (2004) (200)
- 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. (1998) (199)
- Schizophrenia as a GSK-3 dysregulation disorder (2007) (193)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association (2016) (192)
- Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. (2013) (173)
- Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project. (2016) (172)
- Postnatal Psychiatric Illness: the Impact on Partners (1993) (172)
- Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014) (172)
- GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila (2004) (169)
- Blood-based biomarkers of Alzheimer's disease: challenging but feasible. (2010) (169)
- Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies (2019) (167)
- Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology (2014) (166)
- Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease (2010) (163)
- Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters (2001) (159)
- Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations (1999) (157)
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (2006) (156)
- Abnormalities of Wnt signalling in schizophrenia – evidence for neurodevelopmental abnormality (1998) (153)
- Genetic architecture of subcortical brain structures in 38,851 individuals (2019) (148)
- Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls (2011) (148)
- AddNeuroMed and ADNI: Similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America (2011) (146)
- Education increases reserve against Alzheimer’s disease—evidence from structural MRI analysis (2012) (146)
- Developing novel blood-based biomarkers for Alzheimer's disease (2014) (146)
- The AddNeuroMed framework for multi‐centre MRI assessment of Alzheimer's disease : experience from the first 24 months (2011) (145)
- p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells (2007) (144)
- A feasibility and tolerability study of lithium in Alzheimer's disease (2008) (144)
- Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. (2004) (143)
- Assessment Scales in Old Age Psychiatry (1999) (143)
- Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease (2011) (142)
- Tocopherols and tocotrienols plasma levels are associated with cognitive impairment (2012) (140)
- MRI Measures of Alzheimer's Disease and the AddNeuroMed Study (2009) (140)
- Biomarkers for Alzheimer's disease therapeutic trials (2011) (138)
- GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila (2004) (138)
- NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology (2017) (133)
- Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood. (2012) (132)
- Four Components Describe Behavioral Symptoms in 1,120 Individuals with Late‐Onset Alzheimer's Disease (2006) (130)
- Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment (2012) (130)
- Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice (2009) (129)
- SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease (2010) (128)
- Risk of developing dementia in people with diabetes and mild cognitive impairment (2010) (125)
- Inflammatory Proteins in Plasma Are Associated with Severity of Alzheimer’s Disease (2013) (122)
- Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis (2017) (122)
- DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. (2006) (121)
- Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease (2004) (120)
- Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease (2011) (120)
- Dishevelled Regulates the Metabolism of Amyloid Precursor Protein via Protein Kinase C/Mitogen-Activated Protein Kinase and c-Jun Terminal Kinase (2001) (119)
- Different multivariate techniques for automated classification of MRI data in Alzheimer’s disease and mild cognitive impairment (2013) (117)
- Sensitivity and Specificity of Medial Temporal Lobe Visual Ratings and Multivariate Regional MRI Classification in Alzheimer's Disease (2011) (116)
- Neurofibrillary tangles and tau phosphorylation. (2001) (116)
- Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease. (2013) (114)
- Genome-wide Association Study of Alzheimer’s disease with Psychotic Symptoms (2011) (114)
- Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration (2019) (114)
- Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain (2014) (112)
- Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease (2010) (111)
- Glycogen synthase kinase-3β immunoreactivity is reduced in the prefrontal cortex in schizophrenia (2001) (111)
- A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method (2011) (110)
- CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice (2019) (109)
- CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice (2019) (109)
- Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer’s disease neuropathology (2018) (109)
- Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation (2001) (108)
- Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease (1997) (107)
- Cross-tissue methylomic profiling strongly implicates a role for cortex-specific deregulation of ANK1 in Alzheimer’s disease neuropathology (2014) (106)
- Sites of phosphorylation in tau and factors affecting their regulation. (2000) (106)
- Genetic studies on chromosome 12 in late-onset Alzheimer disease. (1998) (105)
- Mitochondrial genes are altered in blood early in Alzheimer's disease (2017) (104)
- Inflammatory biomarkers in Alzheimer's disease plasma (2019) (104)
- Inflammatory biomarkers in Alzheimer's disease plasma (2019) (104)
- Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease (2015) (101)
- The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume (2016) (99)
- Long-term predictors of cognitive outcome in a cohort of older people with hypertension. (2000) (99)
- Rate of progression of cognitive decline in Alzheimer’s disease: effect of butyrylcholinesterase K gene variation (2005) (98)
- Blood-Based Proteomic Biomarkers of Alzheimer’s Disease Pathology (2015) (98)
- Wnt3a induces exosome secretion from primary cultured rat microglia (2012) (96)
- Circulating Proteomic Signatures of Chronological Age (2014) (96)
- Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions (2005) (95)
- Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease (2001) (95)
- Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study. (2010) (94)
- Practical cut‐offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment (2015) (94)
- The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease (2021) (94)
- Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system (2008) (93)
- Depression, APOE genotype and subjective memory impairment: a cross-sectional study in an African-Caribbean population (2001) (93)
- Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping. (2016) (93)
- The effects of commonly prescribed drugs in patients with Alzheimer’s disease on the rate of deterioration (2006) (90)
- Combining MRI and CSF measures for classification of Alzheimer's disease and prediction of mild cognitive impairment conversion (2011) (90)
- Identification of cis-regulatory variation influencing protein abundance levels in human plasma. (2012) (89)
- Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease (2019) (89)
- Heterogeneous patterns of brain atrophy in Alzheimer's disease (2018) (88)
- Apathy and cortical atrophy in Alzheimer's disease (2011) (88)
- A blood gene expression marker of early Alzheimer's disease. (2013) (87)
- Plasma transthyretin as a candidate marker for Alzheimer's disease. (2012) (86)
- Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons (2000) (83)
- Plasma Based Markers of [11C] PiB-PET Brain Amyloid Burden (2012) (83)
- Biomarkers for disease modification trials--the innovative medicines initiative and AddNeuroMed. (2007) (82)
- Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis (2014) (81)
- SORL1 variants and risk of late-onset Alzheimer’s disease (2008) (80)
- Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease (2005) (79)
- Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer’s disease (2008) (78)
- The reliability of a deep learning model in clinical out-of-distribution MRI data: a multicohort study (2019) (78)
- Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease (2016) (78)
- Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease. (1996) (78)
- Insight, cognition and quality of life in Alzheimer's disease (2009) (78)
- The Antidepressant Clomipramine Regulates Cortisol Intracellular Concentrations and Glucocorticoid Receptor Expression in Fibroblasts and Rat Primary Neurones (2003) (76)
- Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease. (2007) (76)
- Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment (2013) (76)
- Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease. (2010) (76)
- Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals. (2011) (75)
- A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease (2009) (75)
- Guidelines on drug treatments for Alzheimer's disease (1997) (75)
- A Decade of Blood Biomarkers for Alzheimer’s Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication (2017) (74)
- Genetic risk of Alzheimer's disease: advising relatives (2001) (74)
- Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum (2019) (74)
- Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups—The AddNeuroMed study (2011) (72)
- Apolipoprotein E genotyping in Alzheimer's disease (1996) (72)
- Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α‐/γ‐tocotrienols and γ‐tocopherol (2013) (72)
- Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study (2019) (71)
- Alzheimer Risk Variant CLU and Brain Function During Aging (2013) (71)
- Protein aggregates and dementia: is there a common toxicity? (2002) (71)
- A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD) (2011) (70)
- Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications. (2003) (70)
- Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes. (1998) (67)
- Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut‐offs (2014) (67)
- Smell identification function as a severity and progression marker in Alzheimer's disease (2013) (66)
- The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics (2018) (66)
- Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer’s Disease in Two Independent Cohorts (2014) (65)
- Complement activation as a biomarker for Alzheimer's disease. (2012) (65)
- Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2009) (64)
- α-2 macroglobulin gene and Alzheimer disease (1999) (64)
- Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 β gene and promoter in late onset Alzheimer's disease (2001) (64)
- Depression in Alzheimer's disease: The effect of serotonin receptor gene variation (2003) (63)
- Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil (2018) (62)
- Glycogen synthase kinase‐3β and tau genes interact in Alzheimer's disease (2008) (62)
- The dementias (2002) (62)
- Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? (2000) (62)
- PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK‐3 (2006) (61)
- Disturbance of Notch-1 and Wnt signalling proteins in neuroglial balloon cells and abnormal large neurons in focal cortical dysplasia in human cortex (1999) (61)
- Insulin signalling in Alzheimer′s disease and diabetes: from epidemiology to molecular links (2016) (61)
- The association between APOE and dementia does not seem to be mediated by vascular factors (2000) (61)
- The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. (2012) (61)
- Predicting Progression of Alzheimer’s Disease Using Ordinal Regression (2014) (60)
- An MRI‐based index to measure the severity of Alzheimer's disease‐like structural pattern in subjects with mild cognitive impairment (2013) (60)
- Consensus Statement on Predictive Testing for Alzheimer Disease (1995) (60)
- Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease (2017) (60)
- The microtubule associated protein Tau gene and Alzheimer's disease – an association study and meta-analysis (2001) (60)
- A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer’s disease (2019) (59)
- Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study. (2005) (59)
- Predictors of care home and hospital admissions and their costs for older people with Alzheimer's disease: findings from a large London case register (2016) (59)
- Familial psychiatric presentation of Huntington's disease. (1996) (58)
- Association of ABCA1 with late-onset Alzheimer’s disease is not observed in a case-control study (2004) (58)
- Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression. (2011) (57)
- OPCRIT+: an electronic system for psychiatric diagnosis and data collection in clinical and research settings (2011) (57)
- Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS) (2012) (57)
- A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort (2019) (57)
- Candidate gene association study of insulin signaling genes and Alzheimer's disease: Evidence for SOS2, PCK1, and PPARγ as susceptibility loci (2007) (56)
- Protective variant for hippocampal atrophy identified by whole exome sequencing (2015) (56)
- Shared genetic contribution to ischemic stroke and Alzheimer's disease (2016) (55)
- Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer’s Disease (2016) (54)
- Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges (2015) (54)
- UK Alzheimer's Disease Genetics Consortium (1999) (54)
- The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study (2017) (54)
- Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer’s Disease biomarker discovery cohort (2019) (53)
- Alzheimer's disease in humans and other animals: A consequence of postreproductive life span and longevity rather than aging (2018) (53)
- Plasma biomarkers for Alzheimer's disease: much needed but tough to find. (2012) (53)
- Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. (2007) (53)
- Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease (2019) (52)
- Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. (2000) (52)
- Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group. (1996) (52)
- Apolipoprotein E-∈A allele and Alzheimer's disease (1993) (52)
- The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer’s disease (2017) (51)
- Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia (2012) (51)
- Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease (2009) (51)
- Blood protein predictors of brain amyloid for enrichment in clinical trials? (2015) (51)
- Protective effect of antirheumatic drugs on dementia in rheumatoid arthritis patients (2017) (51)
- Apolipoprotein E: Depressive illness, depressive symptoms, and Alzheimer's disease (1998) (49)
- MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study (2018) (48)
- PET Tau and Amyloid-β Burden in Mild Alzheimer’s Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers (2017) (48)
- Clinical predictors of aggressive behaviour in Alzheimer's disease (1998) (48)
- Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics (2019) (48)
- Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis (2007) (48)
- APOE ε2 Allele Is Associated with Larger Regional Cortical Thicknesses and Volumes (2010) (47)
- Stimulation of MAP kinase by v‐raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau (1995) (47)
- Cross-sectional and longitudinal analyses of outdoor air pollution exposure and cognitive function in UK Biobank (2018) (46)
- Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease (2002) (46)
- Proteomics of Alzheimer’s disease: understanding mechanisms and seeking biomarkers (2007) (46)
- Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI study (2009) (46)
- Association studies of 23 positional/functional candidate genes on chromosome 10 in late‐onset Alzheimer's disease (2007) (45)
- GSK3α exhibits β‐catenin and tau directed kinase activities that are modulated by Wnt (2006) (45)
- Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood (2014) (45)
- Alzheimer's disease and Down's syndrome: an in vivo MRI study (2008) (45)
- Association analysis of 528 intra‐genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease (2008) (45)
- Hippocampal Proton MR Spectroscopy in Early Alzheimer’s Disease and Mild Cognitive Impairment (2011) (44)
- Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology (2015) (44)
- Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease (2011) (44)
- Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes (2015) (44)
- Presenilin 1 Independently Regulates β-Catenin Stability and Transcriptional Activity* (2001) (44)
- Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel 18F-labelled PET tracer targeting P2X7 (2017) (43)
- CERAD neuropsychological battery total score in multinational mild cognitive impairment and control populations: the AddNeuroMed study. (2011) (43)
- Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. (2008) (43)
- Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study (2005) (43)
- No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease (1999) (42)
- Plasma Biomarkers of AD Emerging as Essential Tools for Drug Development: An EU/US CTAD Task Force Report (2019) (42)
- Lishman's Organic Psychiatry (2009) (42)
- Registries and Cohorts to Accelerate Early Phase Alzheimer's Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer's Disease Task Force. (2016) (41)
- Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4 (2008) (41)
- Developing a new model for patient recruitment in mental health services: a cohort study using Electronic Health Records (2014) (41)
- Smell Identification Test as a Treatment Response Marker in Patients With Alzheimer Disease Receiving Donepezil (2009) (41)
- The Dementias Platform UK (DPUK) Data Portal (2019) (40)
- Effects of FTDP‐17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3β identified by mass spectrometry demonstrate certain mutations exert long‐range conformational changes (2001) (40)
- The BDNF val66met polymorphism is not associated with late onset Alzheimer's disease in three case–control samples (2005) (40)
- Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly. (2016) (39)
- Presenilin-1 polymorphism and Alzheimer's disease (1996) (39)
- Alzheimer's Disease and Other Dementias (Including Pseudodementias) (2009) (39)
- Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells (1995) (39)
- Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease (2005) (39)
- Diabetes and dementia (1999) (39)
- Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease. (2016) (39)
- Ageing Increases Vulnerability to Aβ42 Toxicity in Drosophila (2012) (39)
- The NEO‐FFI is a reliable measure of premorbid personality in patients with probable Alzheimer's disease (2006) (39)
- Association studies between risk for late‐onset Alzheimer's disease and variants in insulin degrading enzyme (2005) (38)
- Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease. (2015) (38)
- Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease (2011) (38)
- Commonly prescribed drugs associate with cognitive function: a cross-sectional study in UK Biobank (2016) (37)
- Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition (2016) (37)
- CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study. (2014) (37)
- Ubiquilin 1 polymorphisms are not associated with late‐onset Alzheimer's disease (2006) (37)
- Magnetic resonance imaging and magnetic resonance spectroscopy for detection of early Alzheimer's disease. (2011) (37)
- Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease (2021) (37)
- A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer’s Disease Diagnosis (2015) (37)
- Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions. (2006) (36)
- Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing (2018) (36)
- Education, occupation and retirement age effects on the age of onset of Alzheimer's disease (2009) (36)
- The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease (2001) (35)
- Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay (2019) (35)
- Advanced glycation end products, dementia, and diabetes (2014) (35)
- Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease (2018) (35)
- Association study of the 5-HT2A receptor gene polymorphism, T102C and essential hypertension (2001) (35)
- The function of the microtubule‐associated protein tau is variably modulated by graded changes in glycogen synthase kinase‐3β activity (2000) (34)
- Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease (2018) (34)
- Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease (2003) (34)
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- Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium. (1996) (1)
- O3-02-05: Proteomic identification of plasma biomarkers for hippocampal atrophy in Alzheimer's disease (2008) (1)
- It takes tau to tangle--the molecular biology of Alzheimer's disease. (2001) (1)
- EUROPEAN MEDICAL INFORMATION FRAMEWORK FOR ALZHEIMER’S DISEASE (EMIF-AD): THE BIOMARKER DISCOVERY STUDY (2017) (1)
- Early diagnosis and treatment of Alzheimer's disease (1998) (1)
- Arylsulphatase A pseudo‐deficiency in vascular dementia and Alzheimer's disease (1997) (1)
- No association of polymorphisms in the chat locus with late-onset Alzheimer's disease (2002) (1)
- Proteomic analysis of Parkinson’s disease patient cohorts show similarities in mechanism to Alzheimer’s disease (2021) (1)
- The pathological importance of microtubules and tau (2002) (1)
- Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation (2012) (1)
- GENOMICS AND EPIGENOMICS ANALYSES IN THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY (2018) (1)
- Practical psychiatry of old age, 3rd edn (2002) (1)
- Combinatorial markers of MCI conversion: Cytokines and MRI measures together predict disease progression (2010) (1)
- A register of Munchausen cases (1991) (1)
- Clusterin, an amyloid chaperone protein in plasma is associated with longitudinal brain atrophy in mild cognitive impairment (2010) (1)
- Rare variants in IFFO1, DTNB and NLRC3 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation (2021) (1)
- P3-196: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling (2008) (1)
- Ultrasensitive blood biomarkers to predict cognitive decline and diagnose Alzheimer’s disease in the absence of AT(N) classification as the reference standard (2020) (1)
- Predicting AT(N) pathologies in Alzheimer’s disease from blood-based proteomic data using neural networks (2022) (1)
- Plasma microRNA: A new source of biomarker for Alzheimer's disease (2010) (1)
- CRISPR/Cas9 genome editing of CLU to examine clusterin’s contribution to neurodegeneration and Alzheimer’s disease (2020) (0)
- Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease (2018) (0)
- P1-361: The development of mass spectrometry–based assays for the monitoring of candidate markers of Alzheimer's disease (2008) (0)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (0)
- P3-093 Peripheral biomarkers in Alzheimer’s disease: A novel proteomic-neuroimaging approach (2006) (0)
- P2-256 The relationship between premorbid personality and the behavioural and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease (AD) (2004) (0)
- Multivariate Analysis of MRI Data to Discriminate between Groups and Predict Conversion in Alzheimer's Disease (2010) (0)
- Research Article Plasma proteins predict conversion todementia fromprodromal disease (2014) (0)
- Introduction (2020) (0)
- Are abnormal premorbid personality traits a marker for Alzheimer's disease? A case-control study (2010) (0)
- Search for genetic variability of the phosphoinositide 3-kinase (P13-K) in late onset Alzheimer's disease (2000) (0)
- DYSREGULATED FC GAMMA R-MEDIATED PHAGOCYTOSIS PATHWAY IN ALZHEIMER'S DISEASE: NETWORK-BASED GENE EXPRESSION ANALYSIS (2019) (0)
- No association of salivary tau concentration with Alzheimer’s disease (2019) (0)
- A genotype risk score based on Type 2 diabetes risk factors is associated with lower risk for Alzheimer's disease in APOE e4 carriers (2011) (0)
- DISTINCT NEURAL SIGNATURES OF DIFFERENT APOE GENE POLYMORPHISMS ON HIPPOCAMPAL VOLUME: A LARGE SCALE STUDY IN ALZHEIMER'S DISEASE AND NORMAL HEALTHY AGEING (2014) (0)
- Slow axonal transport of the microtubule-associated protein tau (2000) (0)
- P1-089: Biochemical characterization of the B6C3-Tg(APPswe,PSEN1dE9) 85Dbo/J mouse fed a pro-oxidant diet on behalf of the addneuromed group (2008) (0)
- The Year in Neurology 2001 (2003) (0)
- Depression in Elderly People (2020) (0)
- Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning (2022) (0)
- Psychological treatments for depression (2020) (0)
- Dementia: Molecules, methods and measures. Edited by I. Hindmarch, H. Hippius and G. Wilcock. John Wiley & Sons, Chichester, 1991. Price £40 (1992) (0)
- THE FUTURE OF ELECTRONIC HEALTH RECORDS AND BIG DATA IN DEMENTIA RESEARCH (2017) (0)
- Erratum: Gait in mild Alzheimer's disease: Feasibility of multi-center measurement in the clinic and home with body-worn sensors: A pilot study (Journal of Alzheimer's Disease (2018) 63:1 (331-341) DOI: 10.3233/JAD-171116) (2018) (0)
- P1-059 Semantic aspects of language in mild cognitive impairment: a cross-sectional study (2004) (0)
- P3-245: Association analysis of tau and progranulin with late-onset Alzheimer's disease in a large caucasian U.K. sample (2008) (0)
- COMPARING CONVERSION FROM MILD COGNITIVE IMPAIRMENT TO ALZHEIMER'S DISEASE IN DIFFERENT COHORTS (2014) (0)
- Hyperphosphorylation of tau and neurofilament by constitutive activation of CDK5 in PTEN deficient cerebellum (2006) (0)
- Long life or old age? (Working with the elderly) (1992) (0)
- P1-014 Principal components analysis of the neuropsychiatric inventory in Alzheimer's disease (2004) (0)
- Possible Future Treatments and Preventative Strategies for Alzheimer's Disease (2002) (0)
- Activation by dexamethasone of a new green fluorescent protein-glucocorticoid receptor (GR) chimera in cell lines and rat cortical neurones (2000) (0)
- P3-265: Testing for association between Alzheimer's disease with psychosis and variants identified as influencing risk of schizophrenia (2008) (0)
- PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY (2017) (0)
- [P3-232]: A PARKINSON\textquotesingles DISEASE PROTEIN BIOMARKER PANEL USING THE SOMAMER ASSAY AND MACHINE LEARNING (2017) (0)
- The effects of pioglitazone on tau phosphorylation in apoE models of insulin resistance (2010) (0)
- S3-04-06: Deletion of IRS2 reduces amyloid deposition, inhibits GSK-3 and rescues behavioral deficits in APP transgenic mice (2008) (0)
- Phosphorylation of tau in cells : the role of glycogen synthase kinase-3. (2010) (0)
- Lovestone S, Rochester L. Gait in Mild Alzheimer’s Disease: Feasibility of Multi- Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot (2018) (0)
- Physical treatments for depression (2020) (0)
- Correction to: The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer’s disease (2018) (0)
- O2-02-05 Novel candidate genes for late-onset Alzheimer’s disease from a large scale association study of 20K functional variants (2006) (0)
- Haplotype structure of the 17 q 21 region in progressive supranuclear palsy and corticobasal degeneration (0)
- AD TMT-SRM Assay - delivering simultaneous quantitation of 9 key plasma proteins in clinical cohorts relevant to AD research (2011) (0)
- Cortical atrophy rates in Alzheimer's patients and subjects with mild cognitive impairment from the AddNeuroMed data collection (2010) (0)
- Identification of blood-based complement biomarkers in Alzheimer's disease (2012) (0)
- Antidepressants enhance intracellular access of cortisol in primary rat neurones (2002) (0)
- No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease. (2015) (0)
- The year in neurology 2002 (2002) (0)
- P2-160: The use of mass spectrometry for multisite phosphorylation assays for tau protein (2008) (0)
- Plasma transthyretin as a candidate marker of cognitive decline and severity in Alzheimer's disease (2010) (0)
- P4-122 Genetic association of an APP binding protein gene with late onset Alzheimer's disease (2004) (0)
- DYSREGULATED FC GAMMA R-MEDIATED PHAGOCYTOSIS PATHWAY IN ALZHEIMER'S DISEASE: NETWORK-BASED GENE EXPRESSION ANALYSIS (2019) (0)
- Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. (2022) (0)
- EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE (2017) (0)
- COMPARING CONVERSION FROM MILD COGNITIVE IMPAIRMENT TO ALZHEIMER'S DISEASE IN DIFFERENT COHORTS (2014) (0)
- Oral and Poster Papers Submitted for Presentation at the 5th Congress of the EUGMS “Geriatric Medicine in a Time of Generational Shift September 3–6, 2008 Copenhagen, Denmark (2008) (0)
- P3-022: Correlation of plasma biomarkers with clinical measures of Alzheimer's disease (2008) (0)
- Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease (2021) (0)
- Presenilin modulates the activity of dishevelled in the WNT pathway (2000) (0)
- Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease (2021) (0)
- Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants (2022) (0)
- Blood biomarkers for Alzheimer’s disease (2014) (0)
- Cross-sectional and longitudinal analyses of outdoor air pollution exposure and cognitive function in UK Biobank (2018) (0)
- Explorer The Edinburgh Consensus : Preparing for the advent of disease-modifying therapies for Alzheimer ' s disease (2017) (0)
- Monitoring the intracellular fate of apolipoprotein E: Implications for Alzheimer's disease (2000) (0)
- P4-058 Searching chromosome 10 for an AD risk factor — Analysis of a positional and biological candidate (2004) (0)
- Longitudinal volume changes of the hippocampus, parahippocampus and entorhinal cortex improve the prediction of conversion from MCI to Alzheimer's disease (2011) (0)
- DNA methylation differences associated with peripheral biomarkers in the EMIF‐AD cohort (2020) (0)
- Correction: Harnessing Clinical Psychiatric Data with an Electronic Assessment Tool (OPCRIT+): The Utility of Symptom Dimensions (2013) (0)
- Combinatorial, multimodal biomarkers from large variable datasets findings from the addneuromed study (2010) (0)
- P4-132 No evidence for association between the APH-1 and PEN-2 components of the gamma secratase complex with late onset Alzheimer's disease (2004) (0)
- Synaptic proteins relate to memory scores in preclinical Alzheimer’s disease and cognitively healthy controls depending on amyloid (2020) (0)
- P1-087 CHARACTERIZATION OF AMYLOID DEPOSITION IN TgCRND8 MOUSE MODEL (2008) (0)
- Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease (2023) (0)
- A genome screen to identify loci that modify the age-of-onset of Alzheimer's disease (2002) (0)
- CSF proteomic profiling of mild cognitive impairment individuals with suspected nonâ•’Alzheimerâ•Žs disease pathophysiology: Developing topics (2020) (0)
- Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage Neuroimaging (2015) (0)
- Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease (2020) (0)
- 385 Genetic and environmental risk factors : Association with non-cognitive symptoms and cognitive decline in late-onset Alzheimer's disease (1996) (0)
- Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration (2019) (0)
- Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2019) (0)
- DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT (2017) (0)
- Plasma inflammatory markers correlate with severity in Alzheimer's disease (2010) (0)
- P2-102 Axonal transport and behavioural defects in drosophila expressing wild-type and mutant Tau (2004) (0)
- Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study (2020) (0)
- O4-03-02 Endocytosis, synaptic transmission and mitochondria are defective in the neuromuscular junction in drosophila larvae over-expressing tau (2004) (0)
- Oxidative damage and the neuropathology of Alzheimer's disease in Drosophila (2010) (0)
- P4-090 Evidence of association with late onset Alzheimer's disease on chromosome 10Q (2004) (0)
- P1-219 Three components describe behavioural symptoms in 1120 individuals with late-onset Alzheimer’s disease (2006) (0)
- Identification of a possible proteomic biomarker in Parkinson’s disease: discovery and replication in blood, brain and cerebrospinal fluid (2022) (0)
- IC-P-091 ANALYSIS OFCEREBRALLOBARMICROBLEEDS AND DECREASED CEREBRAL BLOOD FLOW IN A MEMORY CLINIC SETTING (2014) (0)
- Review Article The future of blood-based biomarkers for Alzheimer's disease (2014) (0)
- APOE and Alzheimer's disease: Is tau the link? (2000) (0)
- INCREASED CSF AMYLOID-β 1-38 AND 1-40 CONCENTRATIONS IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT WITH TAU BUT WITHOUT AMYLOID PATHOPHYSIOLOGY (2018) (0)
- Teaching old drugs new tricks: Do cardiovascular medications effect cognitive decline? (2020) (0)
- MRI PREDICTORS OF AMYLOID PATHOLOGY: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY (2018) (0)
- Cellular Phenotyping of Hippocampal Progenitors Exposed to Patient Serum Predicts Progression to Alzheimer's Disease (2019) (0)
- Cytoskeletal proteins in Lewy Body Dementia (1996) (0)
- Effects of APOE-ε4 and APOE-ε2 alleles on hippocampal volumes in 1,412 healthy young adolescents: The IMAGEN study (2013) (0)
- [P1–291]: WITHDRAWN (2017) (0)
- Classification of Alzheimer's disease using multiplex plasma-based biomarkers (2012) (0)
- THE KINESIN LIGHT CHAIN 1 POLYMORPHISM rs 8702 IS ASSOCIATED WITH ELEVATED CSF LEVELS OF SECRETED FORMS OF AMYLOID PRECURSOR PROTEIN (2008) (0)
- Dementia in Alzheimer’s Disease: A Comparison of MRI and 1H-MRS Findings Between Alzheimer’s Disease and Mild Cognitive Impairment (2009) (0)
- S1-04-05 GSK-3: its role in tau phosphorylation and synaptic plasticity (2004) (0)
- RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT-LIGHT AND YKL-40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY (2018) (0)
- No association of polymorphisms in the cholinergic locus with late-onset Alzheimer's disease. (2002) (0)
- β-AMYLOID SYNAPTOTOXICITY DRIVES β-AMYLOID PRODUCTION (2017) (0)
- PL-05-03 GSK-3 in Alzheimer’s disease: Pathogenic kinase, biomarker and therapeutic target or ubiquitous bystander? (2006) (0)
- P1-291: Early magnetic resonance imaging results from the addneuromed Alzheimer's disease study (2008) (0)
- P4-106 Evidence for association of the calcium/calmodulin-dependent protein kinase type II gamma isoform (CAMKII γ) with late onset Alzheimer's disease (2004) (0)
- 301 Glycogen synthase kinase-3 and the phosphorylation of tau and APP (1996) (0)
- Neurogenetics: Scientific and Clinical Advances (Series: Neurological Disease and Therapy, Volume 75) Editor: DAVID R. LYNCH New York: Taylor & Francis, 2006, US$198.95 Hardback, 755 pp. ISBN 0 8247 2942 0 (2007) (0)
- Blood based gene expression markers of Alzheimer's Disease phenotypes: a pathway based approach (2014) (0)
- BEST COMBINATORIAL LOW-COST MARKERS TO PREDICT MCI CONVERSION: AN EMIF-AD FEDERATION STUDY (2017) (0)
- Background Cognitive Outcome Cognitive Outcome (0)
- Giving dementia a voice. (2010) (0)
- ASSOCIATIONS BETWEEN CEREBROSPINAL FLUID NEURODEGENERATIVE MARKERS, NEUROFILAMENT-LIGHT AND TOTAL TAU AND CEREBROVASCULAR IMAGING MARKERS (2019) (0)
- Plasma inflammatory markers correlate with severity in Alzheimer's disease (2012) (0)
- Effect of trazodone on cognitive function in people with dementia: Cohort study using UK routinely collected data (2020) (0)
- The use of polygenic risk scores for predicting rate of cognitive decline in Alzheimer's disease (2014) (0)
- Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology (2013) (0)
- GENE EXPRESSION OF ABCA7 DYSREGULATED IN PERIPHERAL BLOOD IS ASSOCIATED WITH DECREASED METABOLIC ACTIVITY IN HIPPOCAMPUS (2016) (0)
- Community care: Italian style. (1988) (0)
- Serum from older adults increases apoptosis and molecular ageing markers in human hippocampal progenitor cells (2022) (0)
- p63α and γ Induce TAU Phosphorylation in Cultured Mammalian Cells (2010) (0)
- Hunting for biomarkers: The complement system in Alzheimer's disease (2012) (0)
- Tract Based Spatial Statistic reveals in 1 microstructural organisation between carriers and non-carriers of the ApoE ε4 2 and ε2 alleles in young healthy adolescents 3 (2020) (0)
- Blood-based biomarkers of Alzheimer's/INS; disease pathology and cognitive decline in non-demented elderly (2013) (0)
- Predicting progression to Alzheimer’s disease with human hippocampal progenitors exposed to serum (2023) (0)
- O2-06-01: A powerful, genome-wide association scan for susceptibility genes for late-onset Alzheimer's disease (2008) (0)
- Delusions in dementia - An investigation into their persistence and predictive value (2002) (0)
- Can Three Months MRI Volumetric Parameters Help the Prediction of Progression from MCI to Alzheimer's Disease? Results from the Addneuromed Study (2010) (0)
- Mutual inhibition between the notch and WNT signalling pathways in mammalian cell lines (2002) (0)
- Edinburgh Research Explorer Alzheimer's disease in humans and other animals; a consequence of post-reproductive lifespan and longevity rather than ageing (2017) (0)
- Wnt3a induces the release of membrane-bound vesicles from primary microglia (2010) (0)
- Hypertension and dementia: Is there a common genetic aetiology? (2000) (0)
- Comprehensive analysis of glycosylation patterns of human plasma clusterin: A putative PTM marker of Alzheimer's disease (2013) (0)
- STRUCTURAL ELUCIDATION OF THE GLYCOSYLATION PROFILES OF HUMAN PLASMA CLUSTERIN IN ALZHEIMER'S DISEASE PATIENTS (2014) (0)
- P4-067 Genetic association studies of insulin-degrading enzyme (IDE) with late onset Alzheimer's disease (LOAD) - Equivocal results from two large case-control studies (2004) (0)
- Small Chronic Alterations in Gene Expression and Circulating Blood Cells in Alzheimer's Disease (2010) (0)
- An Aβ transcription signature (2010) (0)
- Factors affecting tau phosphorylation influence APP processing (2000) (0)
- EMPIRICAL FEATURE SELECTION FOR BIOMARKER AND DISEASE SIGNATURE DISCOVERY: DKK1 OVEREXPRESSION IN VITRO NOMINATES PROTEINS ASSOCIATED WITH ALZHEIMER’S IN VIVO (2016) (0)
- Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer’s Disease (2019) (0)
- TRACT-BASED SPATIAL STATISTIC REVEALS NO DIFFERENCES IN WHITE MATTER BETWEEN CARRIERS AND NON-CARRIERS OF THE APOE E4 AND E2 ALLELES IN YOUNG HEALTHY ADOLESCENTS (2014) (0)
- Genome-wide association study of Alzheimer's with psychotic symptoms (2009) (0)
- Cognitive assessments using mobile technologies: moving beyond the inflection point (2015) (0)
- An investigation in cells, animals and humans (2002) (0)
- Prognosis (2020) (0)
- A MASS SPECTROMETRY-BASED DISCOVERY AND REPLICATION OF A MULTI-ANALYTE CLASSIFIER FOR NEOCORTICAL AMYLOID PATHOLOGY (2017) (0)
- Management of breast cancer. (1992) (0)
- Multiomics machine learning identifies sleep and inflammation molecular pathways in prodromal Alzheimer's Disease (2023) (0)
- P4-389 The MRC London Brain Bank at the IOP: Future strategies in brain banking (2006) (0)
- A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline (2016) (0)
- Corrigendum to “Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH” [Neurosci. Lett. 533 (2013) 96–99] (2013) (0)
- Authors' reply (2001) (0)
- COULD COMPLEMENT INHIBITION BE A GOOD THERAPEUTIC TARGET IN ALZHEIMER’S DISEASE? (2017) (0)
- Donepezilof its Use in Alzheimer's Disease (2000) (0)
- Parkinson ’ s Disease α-Catenin and Wnt Signaling Ox-Phose Genes and Alzheimer ’ s Disease NO and Tardive Dyskinesia Homocysteine and Oxyradical-Induced Cognitive Impairment (2004) (0)
- O3-02-06 Linkage analysis of AD SIB pairs indicates evidence of interaction between genes regulating beta-amyloid degradation (2004) (0)
- PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER’S DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT (2018) (0)
- DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER\textquotesingleS DISEASE PATHOLOGY AND PROGRESSION (2017) (0)
- Tau sites abnormally phosphorylated and protein kinases and phosphatases involved (2010) (0)
- Neurofilament light and cognitive performance: Associations with amyloid and vascular pathologies in individuals with mild cognitive impairment (2020) (0)
- Modelling tauopathies in Drosophila (2002) (0)
- NR9. Neurobiological aspects of dementia (2010) (0)
- THE ASSOCIATION OF LONGITUDINAL PLASMA NFL WITH POSTMORTEM NEUROPATHOLOGY (2018) (0)
- Investigating psychosis candidate genes in Alzheimer's disease with psychosis using genome-wide association studies (2009) (0)
- Plasma levels of vitamin E isoforms and of coenzyme Q10 in cognitively normal, MCI and AD (2009) (0)
- Better together for better dementia research and care. (2016) (0)
- Association of magnetic resonance imaging white matter lesions and cognitive decline in Alzheimer's disease (2013) (0)
- Advances in dementia research (2002) (0)
- 1 Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer ' s disease brain (2016) (0)
- O1-02-08: The innomed/addneuromed framework for multicenter MRI assessment of longitudinal changes in Alzheimer's disease (2008) (0)
- Sex-specific metabolic pathways associate with Alzheimer's Disease (AD) endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery (EMIF-AD MBD) cohort (2021) (0)
- Clinical Informatics and Dementia Research in the United Kingdom (2015) (0)
- The Effect of Age Correction on Multivariate Classification in Alzheimer’s Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects (2015) (0)
- Fine mapping of Alzheimers disease linkage region on chromosome 10 (2002) (0)
- The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics (2018) (0)
- PS03.03 Treatment of the Dementia Disease Process (2000) (0)
- Peripheral signatures of the clusterin-DKK neurotoxicity pathway as potential blood-based biomarkers (2013) (0)
- P1-332 Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer’s disease (2006) (0)
- Introduction (2020) (0)
- P4-046 Association of late onset Alzheimer's disease with genetic variation in multiple members of a gene family involved in neuronal apoptosis (2004) (0)
- Identification of plasma proteome signatures associated with ATN framework using SOMAscan (2020) (0)
- DISCOVERY AND VALIDATION OF PLASMA BIOMARKERS RELATING TO CSF MEASURES OF ALZHEIMER'S DISEASE PATHOLOGY (2014) (0)
- Biological Research on Dementias (2002) (0)
- Perspective Developing novel blood-based biomarkers for Alzheimer's disease (2014) (0)
- Role of GSK3beta in tau phosphorylation (2002) (0)
- Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease (2019) (0)
- Publisher Correction: Pattern of Altered Plasma Elemental Phosphorus, Calcium, Zinc, and Iron in Alzheimer’s Disease (2019) (0)
- P4-388 The effects of NSAIDs and TZDs on the rat cortical proteome: A 2D-ge screen for regulated proteins potentially neuroprotective against AD (2006) (0)
- P2-131: p53 family members induce the phosphorylation of human tau in cultured mammalian cells (2008) (0)
- Synthesis and evaluation of novel F-18-labelled P2X(7) receptor antagonists (2015) (0)
- Components of the WNT signalling cascade affect APP metabolism (2000) (0)
- Dementia with Lewy Bodies: Résumeacute; of pathological workshop sessions (1996) (0)
- Correction to: Wnt3a induces exosome secretion from primary cultured rat microglia (2020) (0)
- Effects of freezer storage time on levels of complement biomarkers (2017) (0)
- Expression of an Aβ transcription signature gene set in mouse and human brain (2010) (0)
- P4-138 COGNITIVE IMPAIRMENT IN THE ELDERLY WITH BIPOLAR DISORDER-INFLUENCE OF LANGUAGE DISTURBANCES (2006) (0)
- 753 The intracellular fate of apolipoprotein E is tau-dependent and APOE allele-specific (1996) (0)
- Cerebrospinal fluid tau levels indicate aberrant neuronal plasticity in Alzheimer disease (2020) (0)
- P1-327 Testing for association between Alzheimer’s disease with psychosis and functional gene candidates (2006) (0)
- GENOME-WIDE META-ANALYSIS OF TRANSCRIPTOME PROFILING IDENTIFIES NOVEL DYSREGULATED GENES IMPLICATED IN ALZHEIMER’S DISEASE (2016) (0)
- Development and implementation of a TMT-SRM assay for the qualification of candidate biomarkers of Alzheimer's disease (2010) (0)
- P1-328 Association analysis of 22 positional/functional candidate genes on chromosome 10 with late onset Alzheimer’s disease (2006) (0)
- Title : Cellular phenotyping of hippocampal progenitors exposed to patient serum predicts conversion to Alzheimer ’ s Disease (2017) (0)
- P3-228 Identification of P73 as a novel antagonist of notch signalling (2006) (0)
- Voxel-based assessment of asymmetrical hippocampal and entorhinal atrophy in MCI: A longitudinal MRI investigation from the addneuromed study (2010) (0)
- Apoe, Research Criteria and Dementia Neuropathology (1997) (0)
- Cellular Phenotyping of Hippocampal Progenitors Exposed to Patient Serum Predicts Progression to Alzheimer\textquotesingles Disease (2019) (0)
- Genetic counselling. (1977) (0)
- MARKERS OF CIRCADIAN CLOCK FUNCTION IN ALZHEIMER’S DISEASE (2017) (0)
- Development of a new green fluorescent protein-glucocorticoid receptor (GR) chimera to evaluate the effects of antidepressants and other steroid-independent activators of the GR (2000) (0)
- Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease (2018) (0)
- ABERRANT CYTOSKELETAL PHOSPHORYLATION AS A PATHOGENIC MECHANISM IN NEURODEGENERATIVE DISEASES - MECHANISMS OF CYTOSKELETAL PHOSPHORYLATION STUDIED IN CULTURED-CELLS AND TRANSGENIC ANIMALS (1995) (0)
- The Brain: Degeneration, Damage and Disorder, edited by J. Metcalfe (1999) (0)
- Discovery of peripheral biomarkers of alzheimer'/INS;s disease pathology (2013) (0)
- Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease. (2023) (0)
- Genetic influences on metabolite levels in Alzheimer’s disease (2015) (0)
- Protective variant for rate of hippocampal volume loss identified by whole exome sequencing in APOE-ε3ε3 males with MCI (2013) (0)
- PLASMA BIOMARKERS OF NEOCORTICAL AMYLOID BURDEN: AN IN-DEPTH PLASMA PROFILE USING LC-MS (2016) (0)
- Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice (2021) (0)
- P4-110 A systematic scan of chromosome 10 single nucleotide polymorphisms identifies novel candidate genes showing strong association to Alzheimer's disease (2004) (0)
- Correction to "Glycosylation of Human Plasma Clusterin Yields a Novel Candidate Biomarker of Alzheimer's Disease". (2016) (0)
- Multiplexed analysis of plasma in Alzheimer's disease (2012) (0)
- DISTINCT BLOOD PROTEIN MARKERS ARE ASSOCIATED WITH GLOBAL AND REGIONAL BRAIN BETA-AMYLOID DEPOSITION IN ALZHEIMER'S DISEASE (2014) (0)
- P1-326 Statistical and genetic studies on the psychosis sub-phenotype in Alzheimer’s disease (2006) (0)
- P1-335 A powerful association analysis of 496 SNPs in 80 positional candidate genes in a linked region on chromosome 10 for association with late onset Alzheimer’s disease (2006) (0)
- DKK1 OVEREXPRESSION IN VITRO NOMINATES PROTEINS PREDICTING ALZHEIMER’S PATHOLOGY IN BLOOD (2019) (0)
- An examination of previously reported Alzheimer candidate genes within a large genome-wide association dataset (2009) (0)
- Hippocampal proton magnetic resonance spectroscopy and cognitive deficits in patients with mild Alzheimer's disease (2003) (0)
- ASSOCIATION OF CSF TAU WITH HYPERPLASTICITY IN ALZHEIMER’S DISEASE (2019) (0)
- PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY (2017) (0)
- APOE genotype, vascular risk and cognitive impairment in an African Caribbean population (2000) (0)
- CROSS-SECTIONAL STUDIES OF PLASMA PROTEOMIC BIOMARKERS RELATING TO PET AMYLOID AND CSF AMYLOID AND TAU (2016) (0)
- GENOME-WIDE META-ANALYSIS OF TRANSCRIPTOME PROFILING IDENTIFIES NOVEL DYSREGULATED GENES IMPLICATED IN ALZHEIMER’S DISEASE (2016) (0)
- Common brain disorders are associated with heritable patterns of apparent aging of the brain (2019) (0)
- GENE EXPRESSION OF ABCA7 DYSREGULATED IN PERIPHERAL BLOOD IS ASSOCIATED WITH DECREASED METABOLIC ACTIVITY IN HIPPOCAMPUS (2016) (0)
- VKučinskas-2001-2016 (2016) (0)
- Predicting the progression of Alzheimer's disease by plasma-based biomarkers (2012) (0)
- Combining Two Large MRI Data Sets (AddNeuroMed and ADNI) Using Multivariate Data Analysis to Distinguish between Patients with Alzheimer's Disease and Healthy Controls (2010) (0)
- A LONGITUDINAL STUDY OF AN MRI BASED SEVERITY INDEX IN THE ADDNEUROMED COHORT (2014) (0)
- P1-413 SORBS1, c-ABL and c-CBL; insulin signalling proteins in Alzheimer’s disease (2006) (0)
- Genome-wide association study of Alzheimer's disease brain imaging biomarkers and neuropsychological phenotypes in the EMIF-AD Multimodal Biomarker Discovery dataset (2021) (0)
- Erratum: Transcriptomic profiles of Wnt3a and insulin in primary cultured rat cortical neurones (Journal of Neurochemistry (2011) 118 (512-520)) (2012) (0)
- Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). (2009) (0)
- Alzheimer risk variant complement component (3b/4b) receptor-1 (CR1) and brain function during aging (2011) (0)
- P4-139 Dementia in down syndrome. A comparison with Alzheimer’s disease (2006) (0)
- P1-284 Interaction between ADAM12 and SH3MD1 may confer susceptibility to late-onset Alzheimer’s disease (2006) (0)
- The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer’s disease (2017) (0)
- P4-059 CDC2 as a candidate for late-onset Alzheimer's disease (2004) (0)
- Hippocampal Volume as a Biomarker for Enrichment in Clinical Trials in Amnestic Mild Cognitive Impairment: a Comparison of Performance Characteristics in ADNI-1 and AddNeuroMed (P4.089) (2015) (0)
- P3-016: The APOE-ϵ4 allele does not affect rate of cognitive and functional decline in late-onset Alzheimer's disease (AD): Findings from the U.K. Medical Research Council (MRC) genetic resource for AD (2008) (0)
- Aetiology (2020) (0)
- Clinical trial design: Digital health record collaborative efforts in europe (2015) (0)
- Epidemiology and classification of depression (2020) (0)
- BIOCHEM SOC SYMPOSIUM (2001) (0)
- PREDICTING COGNITIVE DECLINE THROUGH STRUCTURAL MRI BIOMARKERS: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY (2018) (0)
- Preface (2009) (0)
- DISTINCT BLOOD PROTEIN MARKERS ARE ASSOCIATED WITH BRAIN REGIONS OF EARLY AMYLOID DEPOSITION IN ALZHEIMER'S DISEASE (2014) (0)
- The reliability of a deep learning model in external memory clinic MRI data: A multi‐cohort study (2020) (0)
- Identifying loci that modify Alzheimer's disease development: A genome screen (2002) (0)
- Biomarker Based and Individualized Prognosis for Patients with Mild Cognitive Impairment: Towards a Personalized Medicine Approach for AD (2019) (0)
- A GENOME-WIDE META-ANALYSIS OF PLASMA CLUSTERIN LEVELS IN THE CHARGE CONSORTIUM (2014) (0)
- The retained ability to display affection and emotion in Alzheimer's disease (2002) (0)
- Clinical presentation of depression in the elderly (2020) (0)
- O2-02-07 Genetic variants on chromosome 9 are associated with late-onset Alzheimer’s disease, variation in allele-specific gene expression, and differential apoptotic response (2006) (0)
- Presenilin modulates the activity of dishevelled 1 in the Wnt pathway (2000) (0)
- DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION (2017) (0)
- The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer’s pathology (2017) (0)
- When Alzheimer met Kraepelin and the molecular biology of dementia (2002) (0)
- TITLE Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD): A Multiple Indicators Multiple Causes (MIMIC) approach. (2009) (0)
- Plasma‐based biomarkers for Aβ and tau predict longitudinal brain atrophy in cognitively healthy elderly and in patients with Alzheimer’s disease (2020) (0)
- Genetic Variants Influencing Human Longevity from Late-Onset Alzheimer’s Disease (LOAD) Genome-Wide Association Studies (GWAS) (2011) (0)
- NOMINATION OF JAK-STAT SIGNALLING AS A TARGET FOR AD THERAPY THROUGH CLINICAL AND MOLECULAR INFORMATICS (2017) (0)
- P1-368 The identification neuronal genes and proteins responsive to insulin and Wnt signalling (2006) (0)
- Genetic influences on the psychotic symptomatology of Alzheimer's disease (2005) (0)
- NOVEL CANDIDATE BLOOD PROTEOME MARKERS OF ALZHEIMER'S DISEASE BRAIN AMYLOID BURDEN: A MULTIPLEX TMT-LC/MS-MS DISCOVERY APPROACH (2014) (0)
- Genome-wide association analysis identifies common variants associated with measures of disease progression in patients with Alzheimer's disease (2012) (0)
- Glycogen synthase kinase-3: A new therapeutic target in Alzheimer's disease (2002) (0)
- Methods and compositions alzheimer in connection with Crohn's (2005) (0)
- Neurons from individual early Alzheimer’s disease patients reflect their clinical vulnerability (2021) (0)
- Cortical thinning patterns in Alzheimer's patients and subjects with mild cognitive impairment from the AddNeuroMed study (2011) (0)
- Genetic information and advice in early and late onset dementia (2005) (0)
- P1-150: β-amyloid activation of DKK-1 via P53 (2008) (0)
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