Sol Spiegelman | Academic Influence

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Sol Spiegelman

Biology

#627

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Molecular Biology

#80

Historical Rank

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Biology

Sol Spiegelman's Degrees

PhD Biochemistry University of Chicago

Why Is Sol Spiegelman Influential?

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According to Wikipedia, Sol Spiegelman was an American molecular biologist. He developed the technique of nucleic acid hybridization, which helped to lay the groundwork for advances in recombinant DNA technology. Early life and education Spiegelman was born in Brooklyn, New York City in 1914. He attended the City College of New York and was initially interested in biology, but found the courses uninspiring and instead chose to focus on math and physics. During his undergraduate work he took a leave of absence to work in a biology laboratory, where he studied the genetics of bacteria. He graduated in 1939 with a bachelor's degree in mathematics. He then began his graduate studies at Columbia University in 1940, studying cellular physiology under the supervision of H.B. Steinbach. Spiegelman joined Steinbach in his move to Washington University School of Medicine two years later, and received his PhD from that institution in 1944. His graduate work focused on what was then known as enzymatic "induction" or "adaptation", now known to reflect changes in gene expression in response to environmental factors. He continued to work at Washington University until 1948, and then took a one-year Public Health Service fellowship at the University of Minnesota.

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Sol Spiegelman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. (1965) (1742)
Electrophoretic separation of viral nucleic acids on polyacrylamide gels. (1967) (700)
An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule. (1967) (539)
LOCALIZATION OF DNA COMPLEMENTARY TO RIBOSOMAL RNA IN THE NUCLEOLUS ORGANIZER REGION OF DROSOPHILA MELANOGASTER. (1965) (508)
Sequence complementarity of T2-DNA and T2-specific RNA. (1961) (281)
A molecular explanation of the bobbed mutants of Drosophila as partial deficiencies of "ribosomal" DNA. (1966) (274)
Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses (1970) (257)
Purification of the DNA polymerase of avian myeloblastosis virus. (1971) (245)
Characterization of RNA synthesized in Escherichia coli after bacteriophage T2 infection (1960) (215)
An approach to the experimental analysis of precellular evolution (1971) (210)
Simultaneous Detection of Reverse Transcriptase and High Molecular Weight RNA Unique to Oncogenic RNA Viruses (1971) (189)
Synthetic DNA–RNA Hybrids and RNA–RNA Duplexes as Templates for the Polymerases of the Oncogenic RNA Viruses (1970) (178)
The selective synthesis of informational RNA in bacteria. (1961) (164)
RNA-dependent DNA Polymerase Activity in Virus-like Particles isolated from Human Milk (1971) (155)
DNA-directed DNA Polymerase Activity in Oncogenic RNA Viruses (1970) (148)
Presence in Human Breast Cancer of RNA homologous to Mouse Mammary Tumour Virus RNA (1972) (145)
The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme. (1965) (142)
Specific template requirments of RNA replicases. (1965) (139)
Comparison of Two Serologically Distinct Ribonucleic Acid Bacteriophages I. Properties of the Viral Particles (1966) (136)
Evolution in vitro: sequence and phenotype of a mutant RNA resistant to ethidium bromide. (1974) (135)
On the redundancy of DNA complementary to amino acid tranfer RNA and its absence from the nucleolar organizer region of Drosophila melanogaster. (1966) (134)
Distinguishing reverse transcriptase of an RNA tumor virus from other known DNA polymerases. (1971) (132)
Complete nucleotide sequence of a replicating RNA molecule. (1973) (130)
Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. (1980) (127)
RESTRICTION OF IN VIVO GENETIC TRANSCRIPTION TO ONE OF THE COMPLEMENTARY STRANDS OF DNA. (1963) (120)
Detection in human breast carcinomas of an antigen immunologically related to a group-specific antigen of mouse mammary tumor virus. (1978) (119)
ON THE ORIGIN OF THE CARBON IN THE INDUCED SYNTHESIS β-GALACTOSIDASE IN ESCHERICHIA COLI (1954) (118)
Human leukaemic cells contain reverse transcriptase associated with a high molecular weight virus-related RNA. (1972) (118)
Origin and Biologic Individuality of the Genetic Dictionary (1962) (117)
High-dose 5-fluorouracil with delayed uridine "rescue" in mice. (1982) (115)
Autocatalytic Synthesis of a Viral RNA in vitro (1965) (112)
A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. (1972) (110)
The identification of the ribosomal RNA cistron by sequence complementarity. I. Specificity of complex formation. (1962) (110)
Distinct cistrons for the two ribosomal RNA components. (1963) (109)
Viruses and human cancer. (1975) (109)
On the chromosomal distribution of DNA complementary to ribosomal and soluble RNA. (1966) (107)
THE INHIBITION OF ENZYME FORMATION BY AMINO ACID ANALOGUES (1952) (107)
The identification of the ribosomal RNA cistron by sequence complementarity. II. Saturation of and competitive interaction at the RNA cistron. (1962) (106)
AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES. (1963) (102)
Properties of retrovirus-like particles produced by a human breast carcinoma cell line: immunological relationship with mouse mammary tumor virus proteins. (1984) (95)
RNA in human leukemic cells related to the RNA of a mouse leukemia virus (leukocytes-RNA-DNA hybridization-rauscher virus-polysomal RNA). (1972) (95)
An overview of thymidine (1980) (93)
Translational Control of Protein Synthesis in a Cell-Free System Directed by a Polycistronic Viral RNA (1963) (90)
Particles containing RNA-instructed DNA polymerase and virus-related RNA in human breast cancers. (1972) (88)
Therapeutic utility of utilizing low doses of N-(phosphonacetyl)-L-aspartic acid in combination with 5-fluorouracil: a murine study with clinical relevance. (1983) (88)
NUCLEAR AND CYTOPLASMIC FACTORS CONTROLLING ENZYMATIC CONSTITUTION (1946) (85)
Potentiation of the anti‐tumor activity of 5FU by thymidine and its correlation with the formation of (5FU) RNA (1980) (80)
Decreased globin messenger RNA in thalassemia detected by molecular hybridization. (1973) (80)
Terminology of Enzyme Formation (1953) (78)
Viral-related RNA in Hodgkins' disease and other human lymphomas. (1972) (78)
Human Sarcomas Contain RNA Related to the RNA of a Mouse Leuemia Virus (1972) (75)
Detection of High-Molecular-Weight RNA in Particles from Human Milk (1972) (74)
Absence of Polymerase Protein in Virions of Alpha-Type Rous Sarcoma Virus (1972) (73)
Protein and ribonucleic acid synthesis in a chloramphenicol-inhibited system. (1961) (72)
Genes and Nucleoproteins in the Synthesis of Enzymes. (1946) (71)
Circularity of the Replicating Form of a Single-Stranded DNA Virus (1964) (70)
Physiological Competition as a Regulatory Mechanism in Morphogenesis (1945) (70)
Modulation of 5-fluorouracil-induced toxicity in mice with interferon or with the interferon inducer, polyinosinic-polycytidylic acid. (1983) (66)
DNA polymerase activities in varions of visna virus, a causative agent of a "slow" neurological disease. (1971) (65)
The sodium and potassium balance in squid nerve axoplasm (1943) (65)
The Present Status of the Transfer of Genetic Information and Its Control (1963) (64)
Burkitt's tumors contain particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA. (1973) (63)
SEPARATION OF THE RNA MESSAGE TRANSCRIBED IN RESPONSE TO A SPECIFIC INDUCER. (1963) (63)
Comparison of Two Serologically Distinct Ribonucleic Acid Bacteriophages II. Properties of the Nucleic Acids and Coat Proteins (1966) (62)
DNA CIRCULARITY AND THE MECHANISM OF STRAND SELECTION IN THE GENERATION OF GENETIC MESSAGES. (1964) (61)
Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus. (1973) (58)
Biochemical and morphologic evidence for the presence of an RNA tumor virus in pulmonary carcinoma of sheep (Jaagsiekte). (1974) (57)
Recognition of size and sequence by an RNA replicase. (1965) (57)
The mechanism of RNA replication. (1968) (57)
Studies on the Phosphate Metabolism of Some Unicellular Organisms. Cold Spring Harbor Symposia on Quantitative Biology, Vol. XIII (1948) (56)
RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas. (1973) (55)
The relation of informational RNA to DNA. (1961) (54)
THE OCCURRENCE OF NATURAL DNA-RNA COMPLEXES IN E. COLI INFECTED WITH T2. (1961) (54)
An estimation of genetic messages in the unfertilized echinoid egg. (1966) (54)
Nuclear DNA sequences present in human leukemic cells and absent in normal leukocytes. (1972) (54)
On the cytoplasmic nature of "long-term adaptation" in yeast. (1950) (54)
In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. (1970) (52)
Incorporation of 5-fluorouracil into murine bone marrow DNA in vivo. (1984) (52)
Leukemia-specific DNA sequences in leukocytes of the leukemic member of identical twins. (1973) (51)
Quantitation of RNA Tumor Viruses and Viruslike Particles in Human Milk by Hybridization to Polyadenylic Acid Sequences (1973) (51)
Exhaustive hybridization and its application to an analysis of the ribonucleic acid synthesized in T4-infected cells. (1968) (51)
Biological and biochemical evidence for an interaction between Marek's disease herpesvirus and avian leukosis virus in vivo. (1973) (51)
RNA-instructed DNA polymerase activity in a cytoplasmic particulate fraction in brains from Guamanian patients (1975) (51)
ISOLATION AND CHARACTERIZATION OF NUCLEAR BODIES FROM PROTOPLASTS OF BACILLUS MEGATERIUM (1958) (51)
A comparative study of the biologic and molecular basis of murine mammary carcinoma: a model for human breast cancer. (1973) (51)
Replicating Form of a Single-Stranded DNA Virus: Isolation and Properties (1963) (50)
CHROMATOGRAPHIC SEPARATION OF ANNEALED AND ENZYMATICALLY SYNTHESIZED RNA-DNA HYBRIDS. (1965) (50)
On the nature of the ribonucleic acid synthesized in the presence of chloramphenicol. (1961) (49)
Oncornavirus-like particles in human skin cancers. (1975) (49)
Evidence for a nonrandom reading of the genome. (1962) (49)
Immunohistochemical detection of a cross-reacting virus antigen in mouse mammary tumors and human breast carcinomas. (1978) (48)
THE FORMATION AND STABILIZATION OF AN ADAPTIVE ENZYME IN THE ABSENCE OF ITS SUBSTRATE (1947) (47)
The purification of a gs antigen of the murine mammary tumor virus and its quantitation by radioimmunoassay. (1976) (47)
Further extracellular Darwinian experiments with replicating RNA molecules: diverse variants isolated under different selective conditions. (1969) (47)
Human breast carcinoma antigen is immunologically related to the polypeptide of the group-specific glycoprotein of mouse mammary tumor virus. (1979) (47)
Purification and detection of reverse transcriptase in viruses and cells. (1974) (47)
Homology Test between the Nucleic Acid of an RNA Virus and the DNA in the Host Cell (1962) (46)
Synthesis of full-length DNA copies of avian myeloblastosis virus RNA in high yields. (1977) (46)
DNA polymerase activities and nucleic acid components of virions isolated from a spontaneous mammary carcinoma from a rhesus monkey. (1971) (46)
Conditions for the selective synthesis of DNA complementary to template RNA. (1973) (44)
Reverse transcriptase and high molecular weight RNA in particles from mouse and human milk. (1972) (43)
Maintenance and Increase of a Genetic Character by a Substrate-Cytoplasmic Interaction in the Absence of the Specific Gene. (1945) (43)
Purification of RNA-instructed DNA polymerase from human leukemic spleens. (1975) (43)
Detection of RNA-instructed DNA polymerase and high molecular weight RNA in malignant tissue. (1972) (43)
Further evidence for oncornaviruses in human milk: the production of cores. (1973) (42)
Deoxyribonucleic Acid Polymerase of Rous Sarcoma Virus: Reaction Conditions and Analysis of the Reaction Product Nucleic Acids (1971) (42)
Virus-related RNA in human and mouse mammary tumors. (1972) (41)
Ribosome-bound beta-galactosidase. (1961) (41)
An in vitro analysis of a replicating molecule. (1967) (41)
The in vitro translation of a monocistronic message. (1965) (40)
Serological Analysis of the Deoxyribonucleic Acid Polymerase of Avian Oncornaviruses II. Comparison of Avian Deoxyribonucleic Acid Polymerases (1972) (40)
Size distribution of "informational" RNA. (1962) (40)
SOME BASIC PROBLEMS IN THE RELATION OF NUCLEIC ACID TURNOVER TO PROTEIN SYNTHESIS (1947) (40)
Evidence for translation of viral-specific RNA in cells of a mouse mammary carcinoma. (1972) (39)
THE EFFECT OF FREE AMINO ACID POOL LEVELS ON THE INDUCED SYNTHESIS OF ENZYMES (1953) (39)
Plasma levels of a viral protein as a diagnostic signal for the presence of tumor : the murine mammary tumor model. (1976) (38)
Reverse transcriptase in leukocytes of leukemic patients in remission. (1976) (38)
Particles with RNA of high molecular weight and RNA-directed DNA polymerase in human brain tumors. (1973) (38)
INTERACTIONS BETWEEN ENZYME-FORMING SYSTEMS DURING ADAPTATION (1947) (38)
Conservation of a viral RNA genome during replication and translation. (1963) (36)
RNA replication: required intermediates and the dissociation of template, product, and Q beta replicase. (1979) (36)
Characterisation of a virus (HL23V) isolated from cultured acute myelogenous leukaemic cells (1976) (36)
Striking augmentation of the in vivo anti-cancer activity of 5-fluorouracil (fu) by combination with pyrimidine nucleosides. An rna effect. Abstr. (1978) (35)
A chemical and physical characterization of echinoid RNA during early embryogenesis. (1966) (35)
ENZYME FORMATION IN PROTOPLASTS OF BACILLUS MEGATERIUM. (1955) (35)
ENZYME FORMATION IN NON-VIABLE CELLS (1953) (35)
Detection of viral proteins in mouse mammary tumors by immunoperoxidase staining of paraffin sections. (1978) (35)
The sequence at the 5' terminus of a self-replicating variant of viral Q-beta ribonucleic acid. (1968) (34)
Serological Analysis of the Deoxyribonucleic Acid Polymerase of Avian Oncornaviruses I. Preparation and Characterization of Monospecific Antiserum with Purified Deoxyribonucleic Acid Polymerase (1972) (33)
Sodium pyrophosphate inhibition of RNA.DNA hybrid degradation by reverse transcriptase. (1978) (33)
The presence of unique DNA sequences after viral induction of leukemia in mice. (RNA tumor virus-nucleic acid hybridization-insertion of viral DNA). (1974) (32)
SUBSTRATE-ENZYME ORIENTATION DURING EMBRYONIC DEVELOPMENT (1945) (32)
A Single-Cell Analysis of the Transmission of Enzyme-Forming Capacity in Yeast. (1951) (32)
Synthesis of DNA complements of natural RNAs: a general approach. (1971) (31)
The cloning of a self-replicating RNA molecule. (1968) (31)
The Physiology and Genetic Significance of Enzymatic Adaptation (1945) (31)
On the use of chloramphenicol-inhibited systems for investigating RNA and protein synthesis. (1958) (29)
Evidence for RNA tumor viruses in human lymphomas including Burkitt's disease. (1973) (29)
The mechanism of Q replication: sequence at the 5' terminus of a 6-S RNA template. (1971) (28)
Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue. (1983) (28)
In Vitro Synthesis of an Infectious Mutant RNA with a Normal RNA Replicase (1966) (28)
The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase. (1967) (28)
Transcriptive expression during sea urchin embryogenesis. (1970) (28)
Human cancer and animal viral oncology (1974) (26)
The Energetics of Transient and Steady States, with Special Reference to Biological Systems (1945) (26)
Unique nuclear DNA sequences in the involved tissues of Hodgkin's and Burkitt's lymphomas. (1973) (25)
The mechanism of inhibition of carbohydrate assimilation by dinitrophenol and azide. (1947) (25)
The kinetics of product appearance and template involvement in the in vitro replication of viral RNA. (1967) (25)
THE RELATION OF ENZYMATIC ADAPTATION TO THE METABOLISM OF ENDOGENOUS AND EXOGENOUS SUBSTRATES (1947) (25)
Protein and Nucleic Acid Synthesis in Subcellular Fractions of Bacterial Cells (1959) (25)
Room-temperature chromatography of nucleic acids on hydroxylapatite columns in the presence of formamide. (1973) (25)
Biochemical characterization of putative subviral particulates from human malignant breast tumors. (1975) (23)
Use of micrococcal nuclease to monitor hybridization reactions with DNA. (1974) (23)
The dissociation of anaerobic metabolism from enzymatic adaptation in yeast. (1947) (23)
NET UTILIZATION OF FREE AMINO ACIDS DURING THE INDUCED SYNTHESIS OF MALTOZYMASE IN YEAST (1953) (23)
Sequence homology between the RNA of Mason-Pfizer monkey virus and the RNA of human malignant breast tumors. (1974) (23)
Plasma levels of a viral protein as a diagnostic signal for the presence of mammary tumor: the effect of tumor removal (1977) (23)
Purification and characterization of the DNA polymerase of human breast cancer particles. (1977) (23)
Evidence of particle-associated RNA-directed DNA polymerase and high molecular weight RNA in human gastrointestinal and lung malignancies. (1974) (22)
A COMPARISON OF THE EFFECTS OF CYANIDE AND AZIDE ON THE DEVELOPMENT OF FROGS' EGGS (1945) (22)
Molecular evidence for a viral etiology of human leukemias, lymphomas, and sarcomas. (1973) (21)
Phosphate metabolism and the dissociation of anaerobic glycolysis from synthesis in the presence of sodium azide. (1948) (21)
THE IN VITRO SYNTHESIS OF A NONINFECTIOUS COMPLEX CONTAINING BIOLOGICALLY ACTIVE VIRAL RNA* (1966) (21)
Diagnosis of primary breast carcinoma through immunohistochemical detection of antigen related to mouse mammary tumor virus in metastatic lesions: A report of two cases (1982) (21)
Mendelian Inheritance of Adaptive Enzymes. (1944) (20)
The effect of tryptophan analogs on the induced synthesis of maltase and protein synthesis in yeast (1955) (20)
Pyrimidine nucleosides enhance the anti-cancer activity of fu and augment its incorporation into nuclear tna. Abstr. (1978) (20)
A rationale for an analysis of RNA replication. (1966) (20)
Serological analysis of reverse transcriptase of the Mason-Pfizer monkey virus. (1974) (20)
THE ENZYMATIC SYNTHESIS OF A CIRCULAR DNA-RNA HYBRID. (1964) (20)
The relationship of visna, maedi and RNA tumor viruses as studied by molecular hybridization. (1973) (20)
Studies in the replication of viral RNA (1967) (19)
The particulate transmission of enzyme-forming capacity in yeast. (1951) (19)
Template capabilities and size distribution of echinoid RNA during early development. (1968) (19)
Direct participation of a host protein in the replication of viral RNA in vitro. (1968) (19)
HYBRID NUCLEIC ACIDS. (1964) (19)
[138] The preparation of an RNA replicase capable of synthesizing biologically active viral RNA☆ (1968) (18)
ON THE ROLE OF THE INDUCER IN THE SYNTHESIS OF MALTASE IN YEAST (1954) (18)
The mechanism of replication: a novel polarity reversal in the in vitro synthesis of Q-beta-RNA and its complement. (1967) (18)
The genetics of microorganisms: By D. G. Catcheside. Pitman Publishing Corporation, New York, Toronto, London. 1951, viii + 223 pp. Price $4.50 (1953) (18)
Antigenic relatedness of the DNA polymerase of human breast cancer particles to the enzyme of the Mason-Pfizer monkey virus. (1977) (17)
Immunological cross-reactions of the major internal protein component from "slow" viruses of sheep. (1977) (17)
Physiological Heterogeneity of Meta-phosphate in Yeast (1947) (17)
Conditions for using DNA polymerase I as an RNA-dependent DNA polymerase. (1974) (17)
An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis. (1967) (16)
Mechanism of Enzymatic Adaptation in Genetically Controlled Yeast Populations. (1944) (16)
THE CONVERSION OF NEGATIVES TO POSITIVES IN “SLOW” ADAPTING POPULATIONS OF YEAST, (1953) (16)
The effect of anaerobiosis on adaptation to galactose fermentation by yeast cells (1945) (15)
Possible diagnostic implications of a mammary tumor virus related protein in human breast cancer (1980) (14)
RNA primer used in synthesis of anticomplementary DNA by reverse transcriptase of avian myeloblastosis virus. (1980) (14)
Examination of the Qβ-Replicase Reaction by Sucrose Gradient and Gel Electrophoresis (1967) (13)
Information transfer from the genome. (1963) (13)
Protection by testosterone from fluorouracil-induced toxicity without loss of anticancer acitvity against autochthonous murine breast tumors. (1980) (13)
Effect of Uridine on the Metabolism of 5-Fluorouracil in the CD8F1 Murine Mammary Carcinoma System (1984) (13)
Evidence for viral involvement in murine and human mammary adenocarcinoma. (1973) (13)
The effects of potassium and calcium on the electrical properties of squid axons (1944) (13)
The immediate precursor of viral RNA in the Q-beta-repicase reaction. (1968) (12)
The synthesis of infectious RNA with a replicase purified according to its size and density. (1966) (12)
LOCALIZATION OF ENZYMES IN NERVES. II. RESPIRATORY ENZYMES (1943) (12)
Substrate Stabilization of Enzyme-Forming Capacity During the Segregation of a Heterozygote. (1952) (11)
Specific cleavage of Qbeta-RNA and identification of the fragment carrying the 3'-OH terminus. (1967) (11)
Replication and Translation of RNA Genomes (1963) (11)
Q-beta-replicase and E. coli transcriptase: requirements for substrate selection as revealed by a study of base analogs. (1970) (11)
Viral‐related DNA sequences before and after transformation by RNA tumor viruses (1973) (11)
A search for an intermediate involving a complement during synchronous synthesis by a purified RNA replicase. (1966) (11)
Nucleoproteins; round-table discussion. (1956) (11)
The inhibition of enzyme formation. (1946) (10)
On the behavior of the E. coli Pz-"beta-galactoside system" introduced into Shigella dysenteriae. (1960) (9)
RNA tumor viruses present in growing and absent in regressing mammary tumors of mice. (1974) (9)
Molecular evidence for the association of RNA tumor viruses with human mesenchymal malignancies. (1976) (9)
THE PREADAPTIVE OXIDATION OF GALACTOSE BY YEAST (1947) (9)
MAXIMA IN RATE-CONCENTRATION CURVES AND THEIR RELATION TO THE STRUCTURAL ASPECTS OF CELLULAR METABOLISM (1945) (9)
Mapping functions in tetrad and recombinant analysis. (1952) (9)
Molecular evidence for viral agents in human cancer and its chemotherapeutic consequences. (1974) (9)
Effects of Some Respiratory Inhibitors on Respiration and Reconstitution in Tubularia.∗ (1942) (8)
REGULATION OF GLOBIN SYNTHESIS IN THE THALASSEMIAS * (1974) (8)
Energy metabolism of biosynthesis at the cellular level. (1952) (8)
Extracellular strategies of a replicating RNA genome. (1971) (8)
The mechanism and direction of RNA synthesis templated by free minus strands of a "little" variant of Q-beta RNA. (1968) (7)
Immunohistochemical evidence for RNA virus related components in human breast cancer. (1979) (7)
Tumor-associated antigens produced by mouse mammary tumor cells in artificial capillary culture. (1982) (7)
Detection of complexes containing 70S RNA and reverse transcriptase in human leukemic plasma. (1973) (7)
A Comparison of the Kinetics of Enzymatic Adaptation in Genetically Homogeneous and Heterogeneous Populations of Yeast (1944) (7)
A simple purification of avian myeloblastosis virus reverse transcriptase for full-length transcription of 35 S RNA. (1980) (7)
The dissociation of carbohydrate assimilation from catabolism. (1947) (6)
The use of arsenate in the analysis of energy relations amongst synthetic reactions. (1950) (6)
Selective interference with viral RNA formation in vitro by specific inhibition with synthetic polyribonucleotides. (1966) (6)
Problems of an RNA Genome Operating in a DNA-Dominated Biological Universe (1966) (6)
DECREASED GLOBIN MESSENGER RNA IN THALASSEMIA BY HYBRIDIZATION AND BIOLOGIC ACTIVITY ASSAYS * (1974) (6)
The apoenzymatic nature of adaptation to galactose fermentation. (1947) (6)
ON THE INTERPRETATION OF RATES OF REGENERATION IN TUBULARIA, AND THE SIGNIFICANCE OF THE INDEPENDENCE OF MASS AND TIME (1944) (6)
MURINE AND HUMAN MELANOMAS CONTAINING A HIGH MOLECULAR WEIGHT RNA ASSOCIATED WITH AN RNA‐INSTRUCTED DNA POLYMERASE (1978) (6)
The Relation of Sporulation and the Range of Variation of the Haplophase to Populational Adaptation (1945) (6)
Therapeutic effect reflected by plasma levels of a viral protein during combination chemotherapeutic treatment of mammary tumor-bearing mice. (1985) (5)
Contrasting characteristics of Marek's disease herpesvirus isolated from chickens with and without avian leukosis virus infection. (1978) (5)
The effects of arsenate and azide on the stability of adaptive enzymes. (1950) (4)
The experimental analysis of gene action. (1948) (4)
COMPLETE NUCLEOTIDE SEQUENCE OF A REPLICATING RNA MOLECULE (1973) (4)
DNA and the RNA viruses (1971) (4)
RIBOSOME-BOUND #-GALACTOSIDASE BY (3)
Mechanism of azide inhibition of synthetic activity and its relation to phosphorylation. (1946) (3)
Ribonucleic acid. I. The test-tube synthesis of a viral nucleic acid. II. The development and use of molecular hybridization. (1974) (3)
Mechanism of action of 5-fluorouracil (fu) in the chemotherapy of the murine mammary tumor. Abstr. (1979) (3)
Sequences related to the RNA tumor viruses in the RNA and DNA of human leukemias and lymphomas. (1975) (3)
The development and use of an extracellular RNA replicating system. (1968) (3)
Genetics of microorganisms. (1954) (3)
Carcinogenesis and the mechanism of gene action. (1947) (3)
Evidence for an RNA tumor viruses in human milk. (1975) (3)
A Comparison of Regeneration and Respiration Rates of Tubularia.∗ (1944) (3)
Breast cancer: molecular basis for a viral etiology. (1974) (3)
Microheterogeneity of protein molecules. (1956) (3)
Radioimmunolocalization of murine mammary tumor virus proteins in gels. (1982) (3)
Unique virus-related DNA sequences in sheep progressive pneumonia lung. (1975) (3)
The relevance of RNA tumor viruses to human cancer. (1973) (2)
Adaptation to a substrate in the absence of its utilization. (1947) (2)
Visna virus: a "slow" neurotropic agent with tumor virus properties. (1971) (2)
The molecular genetics of human cancer and its etiologic implications. (1975) (2)
The Relation of Ribosomal RNA to the Genome (1965) (2)
General discussion: molecular basis of the cause and expression of somatic cell variation. (1958) (2)
Evidence for viruses in human neoplasias. (1975) (2)
The partial purification and some properties of an adaptation-stimulation principle from yeast. (1948) (2)
A note on steady states and the weber-fechner law (1945) (2)
The Role of Template Structure in the Recognition Mechanism of Qβ Replicase (1977) (2)
Use of the Limulus amebocyte lysate endotoxin assay in plasma fractionation. (1982) (1)
The Constants in the `Logistic' Equation (1946) (1)
Systemic treatment of spontaneous autochthonous murine breast tumors (cd8f1) with high dose c. Parvum (cp). Abstr. (1978) (1)
The site of uncoupling of phosphorylation from carbohydrate metabolism in the presence of NaN3. (1946) (1)
Conditions for the selective synthesis of DNA complementary to template RNA. (1973) (1)
[RNA-tumor-virus-like particles in human melanomas with specific relationship to a melanoma virus in mice]. (1975) (1)
Particles from mouse melanoma B16 containing reverse transcriptase and 70S RNA related to human melanoma cytoplasmic RNA (1978) (1)
RNA tumor viruses and human leukemias. (1974) (1)
THE AMINO ACID SEQUENCE OF A TETRADECAPEPTIDE CONTAINING THE REACTIVE SERINE IN E . COLI ALKALINE PHOSPHA TASE (1)
ENZYME FORMATION IN PROTOPLASTS OF BACILLUS MEGA (1)
Reverse transcriptase in acute leukaemia. (1974) (1)
[70S RNA containing particles in human leukemias]. (1973) (1)
Cell Physiology and Pharmacology.J. F. Danielli (1951) (1)
DURATION OF THE QUA TERNARY AND ITS SUBDIVISIONS (1)
Structure and function of immunoglobulin genes and immunoglobulin precursors. (1976) (1)
Molecular Approach to the Etiology of Human Cancer (1976) (1)
A TRIBUTE TO ANNA GOLDFEDER (1982) (1)
The Use Of DNA-RNA Hybridization As An Analytical Tool (1963) (1)
Textbook of Biochemistry.Benjamin Harrow (1947) (0)
Burkitt's TumorsContain Particles Encapsulating RNA-Instructed DNA Polymerase andHighMolecular WeightVirus-Related RNA (Epstein-Barr virus/Rauscher leukemiavirus/70S RNA) (1973) (0)
ThePresence ofUniqueDNA Sequences after Viral Induction ofLeukemia inMice (1974) (0)
ACTION OF CHEMOTHERAPEUTIC AGENTS AND SUBSTRATE ANALOGUES. (1963) (0)
Augmentation of in vivo activity of cytosine arabinoside (ara-c) against a solid murine tumor achieved through biochemical modulation with thymidine (tdr) and n-(phosphono-acetyl)-l- -aspartate (pala). Abstr. (1980) (0)
Book Review:Multi-Enzyme Systems. Four Special Lectures Given to University College, London, in May 1948. Malcolm Dixon (1951) (0)
Comparative Studies on the Molecular Basis for a Viral Involvement in Murine and Human Mammary Adenocarcinoma (1975) (0)
Purified Pancreatic Lipase (1956) (0)
137. The Localization of MMTV Proteins in Mouse Epididymis is Due to a Non-viral Milk Component (1982) (0)
Leukemia-Specific DNA Sequences inLeukocytes oftheLeukemic MemberofIdentical Twins (virogene hypothesis/RNA-directed DNA polymerase) (1973) (0)
ERROR-CORRECTING MECHANISM BY R. B. SETLOW AND W. L. CARRIER (0)
Biochemical Evidence for Viral Involvement in Human Breast Cancer (1975) (0)
Colony-stimulating activity (csa) as a hormonal marker of human tumor cell lines. Csa from urinary bladder carcinoma (ubc). Abstr. (1981) (0)
Letter from Sol Spiegelman to Martin R. Pollock (1951) (0)
Nuclear and cytoplasmic factors controllin enzymatic constitution. (1946) (0)
Ribonucleic Acid Bacteriophages (0)
Subject Index, Vol. 1, 1973 (1973) (0)
Protection by substrate against inhibition of enzymatic adaptation by protein denaturants. (1948) (0)
An improved procedure for purifying RNA tumor viruses from malignant tissue. (1977) (0)
Letter: Reverse transcriptase in acute leukaemia. (1974) (0)
Introduction a la Biochimie Generale.Marcel Florkin (1947) (0)
[Reverse transcriptase liberated from blood plasma of mice and leukemic chickens]. (1973) (0)
Book Review:The Chemistry and Technology of Enzymes. Henry Tauber (1949) (0)
Method for the in vitro synthesis of biologically active intact nucleic acid and preparation of replicases that are suitable here for (1966) (0)
Contents, Vol. 1, 1973 (1973) (0)
[Identification of a "factor" of deoxyribonuclease in reactions with the reverse transcriptase of AMV]. (1973) (0)
Proceedings: Genetics and the cancer cell: molecular evidence for a viral etiology of human cancer. (1972) (0)
Ultrafiltration membrane on the basis of heteroaromatic polymers (1977) (0)
Telegram from Sol Spiegelman to Arthur Kornberg (1959) (0)
Book Review:Enzymes and Their Role in Wheat Technology. J. Ansel Anderson (1947) (0)
In vitro replication of viral RNA. (1968) (0)
Biochemical evidence for the presence of RNA tumor viruses in human leukemic plasma. (1974) (0)
Book Review:Advances in Enzymology and Related Subjects of Biochemistry. F. F. Nord (1949) (0)
The first test tube synthesis of a replicating viral nucleic acid: a tribute to Ichiro Haruna. (1978) (0)
Particles withRNA ofHighMolecular WeightandRNA-Directed DNA Polymerase inHumanBrainTumors (1973) (0)
Book Review:Advances in Protein Chemistry. Volume II. M. L. Anson, John T. Edsall (1947) (0)
Prevention of 5-fluorouracil (5-fu)-induced leukopenia with enhancement of antitumor activity. Abstr. (1979) (0)
Respiratory Inhibition and Reversible Fusion of (1975) (0)
DISCUSSION OF PART VII (1975) (0)
DETECTION OF A CROSS-REACTING VIRUS ANTIGEN IN MOUSE MAMMARY TUMORS AND HUMAN BREAST CARCINOMAS' (1978) (0)
Letter from Sol Spiegelman to Rollin D. Hotchkiss (1947) (0)
THE SYNTHESISOFO-GALACTOSIDASE BY A CELL-FREE PREPARATIONFROM ESCHERICHIACOLI BYTADANORI KAMEYAMA*ANDG.DAVIDNoVELLI (1962) (0)
RNA tumor viruses and human lymphomas. (1974) (0)
Proceedings: Cross-hybridization of DNA complementary to one immunoglobulin light-chain mRNA with mRNA of other light-chains. (1975) (0)
Comparison of the mechanisms whereby NaN3 and 2-4-dinitrophenol suppress anaerobic carbohydrate assimilation. (1947) (0)
Currents in Biochemical Research: Thirty-One Essays Charting the Present Course of Biochemical Research and Considering the Intimate Relationship of Biochemistry to Medicine, Agriculture and Social Problems.David E. Green (1948) (0)
Proceedings of the NATIONAL ACADEMY OF SCIENCES Volume 47 Number 2 February 15 , 1961 SEQUENCE COMPLEMENTARIITY OF T 2-DNA AND T 2-SPECIFIC RNA * (0)
Molecular Virology of Human Cancer. (1973) (0)
Advances in Enzymology and Related Subjects of Biochemistry. Volume VI.F. F. Nord , C. H. Werkman (1946) (0)
Letter from Sol Spiegelman to Tracy M. Sonneborn (1947) (0)
Proceedings: Limited number of genes coding for the constant-region of immunoglobulin kappa-light-chains in mice. (1975) (0)
A rapid method for the study of genetics in large populations (1937) (0)
UniqueNuclear DNA Sequences intheInvolved Tissues ofHodgkin's andBurkitt's Lymphomas (1973) (0)
Proceedings: Synthesis and characterization of DNA complementary to immunoglobulin light-chain mRNA. (1975) (0)
One Family: Vitamins, Enzymes, Hormones. Benjamin Harrow (1952) (0)
Discussion of Part III (1965) (0)
TRANSFORMATION BY DENATURED DEOXYRIBONUCLEIC ACID (0)

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