Sondra Schlesinger
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American virologist
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Sondra Schlesingerbiology Degrees
Biology
#5185
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#7609
Historical Rank
#1833
USA Rank
Virology
#157
World Rank
#162
Historical Rank
#44
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Biology
Sondra Schlesinger's Degrees
- PhD Virology Stanford University
Why Is Sondra Schlesinger Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sondra Schlesinger is an American virologist and professor emeritus at the Washington University School of Medicine. Early life and education Schlesinger was born in New Jersey in 1934. She was an undergraduate at University of Michigan, Ann Arbor, graduating in 1956 with a degree in chemistry; she remained at the same institution for doctoral work and received her Ph.D. in biochemistry in 1960. She then worked as a postdoctoral fellow at the Istituto Superiore di Sanità in Italy and at the Massachusetts Institute of Technology.
Sondra Schlesinger's Published Works
Published Works
- Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. (1989) (389)
- Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs (1993) (371)
- The Togaviridae and Flaviviridae (1986) (286)
- Processing of high mannose oligosaccharides to form complex type oligosaccharides on the newly synthesized polypeptides of the vesicular stomatitis virus G protein and the IgG heavy chain. (1978) (264)
- Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. (1998) (227)
- Tunicamycin inhibits glycosylation and multiplication of Sindbis and vesicular stomatitis viruses (1977) (227)
- Alphavirus-based expression vectors: strategies and applications. (1996) (227)
- The nonglycosylated glycoprotein of vesicular stomatitis virus is temperature-sensitive and undergoes intracellular aggregation at elevated temperatures. (1979) (207)
- Selection of RNA Replicons Capable of Persistent Noncytopathic Replication in Mammalian Cells (1999) (191)
- Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures. (1999) (186)
- Promoter for Sindbis virus RNA-dependent subgenomic RNA transcription (1990) (179)
- Evidence for specificity in the encapsidation of Sindbis virus RNAs (1989) (172)
- Impaired intracellular migration and altered solubility of nonglycosylated glycoproteins of vesicular stomatitis virus and Sindbis virus. (1977) (169)
- Deletion mapping of sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging (1986) (159)
- Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells (1994) (152)
- Stable alphavirus packaging cell lines for Sindbis virus and Semliki Forest virus-derived vectors. (1999) (146)
- Identification of a second glycoprotein in Sindbis virus. (1972) (138)
- Antigenic characterization of two sindbis envelope glycoproteins separated by isoelectric focusing. (1976) (135)
- Synthesis and infectivity of vesicular stomatitis virus containing nonglycosylated G protein (1978) (134)
- Formation of Sindbis Virus Proteins: Identification of a Precursor for One of the Envelope Proteins (1972) (128)
- Alphavirus vectors for gene expression and vaccines. (1999) (122)
- Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon (1994) (121)
- Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells: the importance of a mutation in the nsP2 gene. (1997) (120)
- Translation of Sindbis virus mRNA: analysis of sequences downstream of the initiating AUG codon that enhance translation (1996) (120)
- The Baculoviruses (1997) (118)
- Recombination between Sindbis virus RNAs. (1991) (117)
- Packaging signals in alphaviruses (1997) (117)
- Effect of α-methylhistidine on the control of histidine synthesis (1964) (116)
- RNAs from two independently isolated defective interfering particles of Sindbis virus contain a cellular tRNA sequence at their 5' ends. (1983) (109)
- A plasmid-based self-amplifying Sindbis virus vector. (1995) (105)
- Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA (1997) (101)
- A role for oligosaccharides in glycoprotein biosynthesis (1980) (100)
- Large-Molecular-Weight Precursors of Sindbis Virus Proteins (1973) (98)
- Alphavirus vectors: development and potential therapeutic applications (2001) (95)
- Interactions between Sindbis virus RNAs and a 68 amino acid derivative of the viral capsid protein further defines the capsid binding site. (1994) (83)
- Alphaviruses — vectors for the expression of heterologous genes (1993) (82)
- Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons (2004) (82)
- Deletion analysis of the capsid protein of Sindbis virus: identification of the RNA binding region (1993) (81)
- Growth of Enveloped RNA Viruses in a Line of Chinese Hamster Ovary Cells with Deficient N-Acetyl-glucosaminyltransferase Activity (1976) (77)
- Complementation between Sindbis viral RNAs produces infectious particles with a bipartite genome. (1991) (75)
- Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a nonstructural protein, nsP4. (1990) (73)
- Formation and Assembly of Alphavirus Glycoproteins (1986) (66)
- Defective virus particles from Sindbis virus. (1972) (65)
- Establishment and maintenance of persistent infection by Sindbis virus in BHK cells (1980) (59)
- The effect of oligosaccharide chains of different sizes on the maturation and physical properties of the G protein of vesicular stomatitis virus. (1981) (59)
- Exogenous and endogenous induction of the histidine-degrading enzymes in Aerobacter aerogenes. (1965) (57)
- Common and distinct regions of defective-interfering RNAs of Sindbis virus (1984) (55)
- Proliferative capacity of mouse peritoneal macrophages in vitro (1978) (55)
- The formation of vesicular stomatitis virus (San Juan strain) becomes temperature-sensitive when glucose residues are retained on the oligosaccharides of the glycoprotein. (1984) (55)
- The effects of inhibitors of glucosidase I on the formation of Sindbis virus. (1985) (52)
- Physical properties of a soluble form of the glycoprotein of vesicular stomatitis virus at neutral and acidic pH. (1983) (51)
- Defective interfering passages of Sindbis virus: nature of the defective virion RNA (1976) (50)
- Defective Interfering Passages of Sindbis Virus: Chemical Composition, Biological Activity, and Mode of Interference (1973) (47)
- Studies of defective interfering RNAs of Sindbis virus with and without tRNAAsp sequences at their 5' termini (1985) (46)
- The effect of amino acid analogues on alkaline phosphatase formation in Escherichia coli K-12. IV. Substitution of canavanine for arginine. (1969) (44)
- Sequence analysis of cDNA's derived from the RNA of Sindbis virions and of defective interfering particles (1982) (44)
- A cell line that expresses a reporter gene in response to infection by Sindbis virus: a prototype for detection of positive strand RNA viruses. (1994) (42)
- The effect of amino acid analogues on alkaline phosphatase. Formation in Escherichia coli K-12. II. Replacement of tryptophan by azatryptophan and by tryptazan. (1968) (42)
- The isolation of pyrimidine deoxyribonucleotides from the acid-soluble extract of thymus. (1957) (41)
- Engineered defective interfering RNAs of Sindbis virus express bacterial chloramphenicol acetyltransferase in avian cells. (1987) (40)
- Defective interfering particles of Sindbis virus do not interfere with the homologous virus obtained from persistently infected BHK cells but do interfere with Semliki Forest virus (1981) (40)
- Replication of lactic dehydrogenase virus and Sindbis virus in mouse peritoneal macrophages. Induction of interferon and phenotypic mixing. (1975) (38)
- Submaxillary Gland of Mouse: Properties of a Purified Protein Affecting Muscle Tissue in vitro (1967) (37)
- Increased Replicative Fitness of a Dengue Virus 2 Clade in Native Mosquitoes: Potential Contribution to a Clade Replacement Event in Nicaragua (2014) (36)
- Defective Interfering Passages of Sindbis Virus: Nature of the Intracellular Defective Viral RNA (1974) (35)
- Mutants of Escherichia coli with an Altered Tyrosyl-Transfer Ribonucleic Acid Synthetase (1969) (35)
- Domains of Virus Glycoproteins (1987) (34)
- Alphaviruses: Semliki Forest Virus and Sindbis Virus Vectors for Gene Transfer into Neurons (2007) (34)
- Effect of acute or chronic infection with lactic dehydrogenase virus (LDV) on the susceptibility of mice to plasmacytoma MOPC-315. (1974) (33)
- Crystallization of Sindbis virus and its nucleocapsid. (1992) (31)
- cis-acting genomic elements and trans-acting proteins involved in the assembly of RNA viruses (1994) (30)
- Structural proteins of lactic dehydrogenase virus. (1973) (30)
- The effects of inhibiting oligosaccharide trimming by 1-deoxynojirimycin on the nicotinic acetylcholine receptor. (1986) (29)
- Effects of 5'-terminal modifications on the biological activity of defective interfering RNAs of Sindbis virus (1988) (28)
- Inhibition of Growth of Escherichia coli and of Homoserine O-Transsuccinylase by α-Methylmethionine (1967) (26)
- Recombination between Sindbis virus RNAs (1991) (26)
- Imidazolepropionate, a nonmetabolizable inducer for the histidine-degrading enzymes in Aerobacter aerogenes. (1965) (23)
- FORMATION AND LOCALIZATION OF THE ALKALINE PHOSPHATASE OF ESCHERICHIA COLI * (1969) (22)
- THE OCCURRENCE OF DEOXY-PYRIMIDINE NUCLEOTIDES IN THE ACID-SOLUBLE EXTRACT OF THYMUS1 (1955) (20)
- Identification of a Compound related to 6-Aminopenicillanic Acid, isolated from Culture Media of Penicillium chrysogenum (1961) (20)
- Alphavirus expression vectors. (2000) (19)
- Enveloped virus acquires membrane defect when passaged in fibroblasts from I-cell disease patients. (1976) (19)
- Evolution of virus and defective-interfering RNAs in BHK cells persistently infected with Sindbis virus (1983) (19)
- Alphavirus cDNA-based expression vectors: effects of RNA transcription and nuclear export. (2003) (17)
- Detection and quantitation of human respiratory syncytial virus (RSV) using minigenome cDNA and a Sindbis virus replicon: a prototype assay for negative-strand RNA viruses. (1998) (17)
- Interactions of tyrosyl transfer ribonucleic acid synthetase from Escherichia coli with its substrates. Inhibition by transfer ribonucleic acid. (1972) (17)
- Restricted replication of two alphaviruses in ricin-resistant mouse L cells with altered glycosyltransferase activities (1979) (17)
- Oligonucleotide mapping studies of standard and defective Sindbis virus RNA (1979) (16)
- RNA viruses as vectors for the expression of heterologous proteins (1995) (15)
- RNA viruses as gene expression vectors (1989) (13)
- Defective RNAs of Alphaviruses (1986) (12)
- Regulated Expression of a Sindbis Virus Replicon by Herpesvirus Promoters (1999) (12)
- Studies on the interaction of tyrosyl-tRNA synthetase from Escherichia coli K12 with tyrosine and with tyrosyl-AMP. (1973) (10)
- Properties of Sindbis virus vectors produced with a chimeric split helper system. (2005) (9)
- EFFECT OF ALPHA-METHYLHISTIDINE ON THE CONTROL OF HISTIDINE SYNTHESIS. (1964) (9)
- Defective particles in alphavirus infections. (1975) (9)
- The effect of amino acid analogues on alkaline phosphatase formation in Escherichia coli K-12. I. Substitution of triazolealanine for histidine. (1967) (9)
- The Togaviridiae and Flaviviridae. Plenum Press, New York, London (1986), 1 vol. (17 x 25,5 cm), 453 + xv pages (1986) (9)
- Properties of tyrosyl transfer ribonucleic acid synthetase from two tyrS mutants of Escherichia coli K-12. (1972) (9)
- Lactic dehydrogenase virus replicates in somatic cell hybrids of mouse peritoneal macrophages and SV40-transformed human fibroblasts. (1976) (7)
- Production of Sindbis, influenza, and vesicular stomatitis viruses in chicken embryo and rat embryo cell suspensions (1974) (5)
- Physical properties of the glycoprotein of vesicular stomatitis virus measured by intrinsic fluorescence and aggregation. (1982) (5)
- Establishment andMaintenance ofPersistent Infection by Sindbis Virus inBHK Cells (1980) (5)
- Effects of neuraminidase of the phenotype of sindbis virus grown in fibroblasts obtained from patients with I-cell disease. (1978) (5)
- Remembrance of immunology past: conversations with Herman Eisen. (2015) (4)
- Deletion Analysis oftheCapsid Protein ofSindbis Virus: Identification oftheRNA Binding Region (1993) (3)
- The effect of amino acid analogues on alkaline phosphatase formation in Escherichia coli K-12. 3. Substitution of 2-methylhistidine for histidine. (1969) (2)
- The Generation and Amplification of Defective Interfering RNAs (2018) (2)
- Virus-based vectors for gene expression in mammalian cells: Sindbis virus (2003) (2)
- Inhibition ofGrowth ofEscherichia coli andof Homoserine O-Transsuccinylase bya-Methylmethionine (1967) (2)
- Aiphavirus-based expression vectors: Strategies and applications (2005) (1)
- sequences at their 5' termini. Sindbis virus with and without tRNAAsp Studies of defective interfering RNAs of (2013) (0)
- Expression of the nonstructural proteins of Sindbis virus in insect cells by a baculovirus vector. (1992) (0)
- WORKSHOP ON PICORNAVIRUSES/TOGAVIRUSES/HEPATITIS/CORONAVIRUSES (1980) (0)
- Formation of RNA and protein in cells infected with standard and defective Sindbis virus (2005) (0)
- Studies ofDefective Interfering RNAsofSindbis Virus Withand Without tRNAASPSequences atTheir 5'Termini (1985) (0)
- Alpha virus vector having a reduced inhibition of the synthesis of cell macromolecules (1997) (0)
- Studies on viral specific rna in bhk baby hamster kidney cells infected with defective interfering passages of sindbis virus (1974) (0)
- The Retroviridae (1995) (0)
- Sindbis VirusExpression Vectors: Packaging ofRNA Replicons byUsingDefective HelperRNAs (1993) (0)
- Indicator - cell line and a method for rns-virus proof (1994) (0)
- Oligonucleotide Mapping Studies ofStandard andDefective (1979) (0)
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