Sriram Subramaniam

Sriram Subramaniam's AcademicInfluence.com Rankings

Sriram Subramaniam

Physics

#6186

World Rank

#8095

Historical Rank

Biophysics

#251

World Rank

#262

Historical Rank

physics Degrees

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Physics

Sriram Subramaniam's Degrees

PhD Biophysics Stanford University
Bachelors Physics California Institute of Technology

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Sriram Subramaniam's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography. (2013) (1948)
Molecular architecture of native HIV-1 gp120 trimers (2008) (812)
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery (2016) (437)
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor (2015) (435)
Molecular mechanism of vectorial proton translocation by bacteriorhodopsin (2000) (396)
Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin. (1993) (383)
Site-specific 3D imaging of cells and tissues with a dual beam microscope. (2006) (314)
Mitochondrial reticulum for cellular energy distribution in muscle (2015) (297)
SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex (2022) (293)
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition (2016) (269)
Three-dimensional structure of a bacterial oxalate transporter (2002) (218)
Protein conformational changes in the bacteriorhodopsin photocycle. (1999) (216)
Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation (2012) (212)
Cryo‐electron microscopy – a primer for the non‐microscopist (2013) (212)
Structural mechanism of glutamate receptor activation and desensitization (2014) (208)
Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure (2010) (195)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (191)
Electron Tomography of the Contact between T Cells and SIV/HIV-1: Implications for Viral Entry (2007) (185)
Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy (2007) (179)
3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells (2010) (177)
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures (2011) (170)
Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy (2014) (164)
Classification and 3D averaging with missing wedge correction in biological electron tomography. (2008) (163)
Focused ion beams in biology (2015) (157)
Ion-Abrasion Scanning Electron Microscopy Reveals Surface-Connected Tubular Conduits in HIV-Infected Macrophages (2009) (147)
Computation of molecular electrostatics with boundary element methods. (1997) (146)
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies (2021) (140)
Protonation state of Asp (Glu)-85 regulates the purple-to-blue transition in bacteriorhodopsin mutants Arg-82----Ala and Asp-85----Glu: the blue form is inactive in proton translocation. (1990) (136)
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex (2017) (134)
Cryo-electron tomography of bacteria: progress, challenges and future prospects (2009) (129)
Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine (2002) (128)
Power Grid Protection of the Muscle Mitochondrial Reticulum. (2017) (125)
Structural Model for 12-Helix Transporters Belonging to the Major Facilitator Superfamily (2003) (114)
3D imaging of mammalian cells with ion-abrasion scanning electron microscopy. (2009) (108)
Atomic Resolution Cryo-EM Structure of β-Galactosidase. (2018) (103)
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating (2016) (95)
Multi-resolution correlative focused ion beam scanning electron microscopy: applications to cell biology. (2014) (92)
Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies (2013) (92)
Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes (2017) (92)
Role of HAMP domains in chemotaxis signaling by bacterial chemoreceptors (2008) (89)
HIV-1 envelope glycoprotein structure. (2013) (89)
High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models (2020) (89)
HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation. (2011) (88)
Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases (2019) (88)
Direct molecular level measurements of the electrostatic properties of a protein surface. (1998) (87)
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy. (2003) (85)
A frequent, GxxxG-mediated, transmembrane association motif is optimized for the formation of interhelical Cα–H hydrogen bonds (2014) (84)
Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N (2018) (80)
Correlative 3D imaging of whole mammalian cells with light and electron microscopy. (2011) (79)
Protein secondary structure determination by constrained single-particle cryo-electron tomography. (2012) (78)
Chemoreceptors in Caulobacter crescentus: Trimers of Receptor Dimers in a Partially Ordered Hexagonally Packed Array (2008) (78)
Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution (2015) (78)
Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports (2014) (77)
Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy (2013) (77)
Three-dimensional electron microscopy at molecular resolution. (2004) (76)
BH3‐in‐groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes (2016) (76)
Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9 (2019) (76)
Direct visualization of receptor arrays in frozen‐hydrated sections and plunge‐frozen specimens of E. coli engineered to overproduce the chemotaxis receptor Tsr (2004) (75)
Membrane protein structure determination using cryo-electron tomography and 3D image averaging. (2009) (75)
Electron tomography in nanoparticle imaging and analysis. (2008) (73)
Resolution advances in cryo-EM enable application to drug discovery. (2016) (72)
Electron Microscopic Analysis of Membrane Assemblies Formed by the Bacterial Chemotaxis Receptor Tsr (2003) (72)
Bridging the imaging gap: visualizing subcellular architecture with electron tomography. (2005) (71)
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization. (1991) (70)
Projection structure and molecular architecture of OxlT, a bacterial membrane transporter (2001) (69)
Structural basis of kainate subtype glutamate receptor desensitization (2016) (69)
Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy* (2006) (69)
Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin. (2009) (68)
Cryo-EM: beyond the microscope. (2017) (67)
Three-Dimensional Electron Microscopic Imaging of Membrane Invaginations in Escherichia coli Overproducing the Chemotaxis Receptor Tsr (2004) (66)
Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle (2016) (66)
Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs (2018) (65)
3D imaging of diatoms with ion-abrasion scanning electron microscopy. (2009) (64)
Cell Surface Filaments of the Gliding Bacterium Flavobacterium johnsoniae Revealed by Cryo-Electron Tomography (2007) (62)
Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin. (1989) (61)
Computer modeling of electrostatic steering and orientational effects in antibody-antigen association. (1995) (60)
Structure and transport mechanism of the bacterial oxalate transporter OxlT. (2004) (60)
Brownian dynamics simulations of protein folding: access to milliseconds time scale and beyond. (1998) (58)
Automated image acquisition and processing using a new generation of 4K x 4K CCD cameras for cryo electron microscopic studies of macromolecular assemblies. (2003) (58)
Electron tomography of viruses. (2007) (57)
Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain (2013) (56)
Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography (2011) (55)
Maturation of the HIV-1 core by a non-diffusional phase transition (2015) (54)
Automatic joint classification and segmentation of whole cell 3D images (2009) (54)
Spatial Localization of the Ebola Virus Glycoprotein Mucin-Like Domain Determined by Cryo-Electron Tomography (2014) (54)
Three-Dimensional Imaging of HIV-1 Virological Synapses Reveals Membrane Architectures Involved in Virus Transmission (2014) (54)
Three-Dimensional Imaging of the Highly Bent Architecture of Bdellovibrio bacteriovorus by Using Cryo-Electron Tomography (2008) (53)
Electron tomography of degenerating neurons in mice with abnormal regulation of iron metabolism. (2005) (53)
CryoEM at IUCrJ: a new era (2016) (52)
Three-Dimensional Imaging of Viral Infections. (2014) (52)
Activation and regeneration of rhodopsin in the insect visual cycle. (1994) (51)
Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin. (1993) (51)
Electron diffraction studies of light-induced conformational changes in the Leu-93 --> Ala bacteriorhodopsin mutant. (1997) (49)
A 3D cellular context for the macromolecular world (2014) (48)
Bimolecular reaction simulation using Weighted Ensemble Brownian dynamics and the University of Houston Brownian Dynamics program. (2000) (48)
Structural plasticity of a transmembrane peptide allows self-assembly into biologically active nanoparticles (2011) (47)
Targeted conformational search with map-restrained self-guided Langevin dynamics: application to flexible fitting into electron microscopic density maps. (2013) (47)
Electron crystallography of bacteriorhodopsin with millisecond time resolution. (1999) (46)
Automated data collection with a Tecnai 12 electron microscope: applications for molecular imaging by cryomicroscopy. (2001) (46)
Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding (2021) (46)
Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters (2011) (46)
Stoichiometry and Absolute Quantification of Proteins with Mass Spectrometry Using Fluorescent and Isotope-labeled Concatenated Peptide Standards*S (2008) (46)
Data management challenges in three-dimensional EM (2012) (45)
Evaluation of denoising algorithms for biological electron tomography. (2008) (44)
Crystallographic analysis of protein conformational changes in the bacteriorhodopsin photocycle. (2000) (44)
Protein electrostatics: rapid multigrid-based Newton algorithm for solution of the full nonlinear Poisson-Boltzmann equation. (1994) (43)
The structure of bacteriorhodopsin: an emerging consensus. (1999) (42)
Chemical mapping of mammalian cells by atom probe tomography. (2012) (41)
Expression, stability, and membrane integration of truncation mutants of bovine rhodopsin. (1997) (41)
The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates. (1991) (41)
An energy-based three-dimensional segmentation approach for the quantitative interpretation of electron tomograms (2005) (41)
Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives (2012) (41)
Structure of trimeric HIV-1 envelope glycoproteins (2013) (40)
Protein Conformational Changes in the Bacteriorhodopsin Photocycle: Comparison of Findings from Electron and X-Ray Crystallographic Analyses (2009) (39)
Compositional mapping of the surface and interior of mammalian cells at submicrometer resolution. (2011) (39)
Structural organization of FtsB, a transmembrane protein of the bacterial divisome. (2013) (38)
Cryoelectron Tomographic Analysis of an HIV-neutralizing Protein and Its Complex with Native Viral gp120* (2007) (38)
Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response (2011) (37)
Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base. (1992) (37)
Structural insights into the mechanism of proton pumping by bacteriorhodopsin (2003) (37)
Molecular mechanism of protein-retinal coupling in bacteriorhodopsin. (1995) (36)
From structure to mechanism: electron crystallographic studies of bacteriorhodopsin (2002) (35)
Spiral Architecture of the Nucleoid in Bdellovibrio bacteriovorus (2010) (35)
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus (2015) (34)
Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase (2016) (34)
Frontiers in Cryo Electron Microscopy of Complex Macromolecular Assemblies. (2019) (33)
Proton translocation by bacteriorhodopsin in the absence of substantial conformational changes. (2002) (33)
A versatile nano display platform from bacterial spore coat proteins (2015) (31)
Building bridges between cellular and molecular structural biology (2017) (31)
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion (2021) (30)
Mapping of Ebolavirus Neutralization by Monoclonal Antibodies in the ZMapp Cocktail Using Cryo-Electron Tomography and Studies of Cellular Entry (2016) (29)
Projection structure of the bacterial oxalate transporter OxlT at 3.4A resolution. (2003) (29)
Structural informatics, modeling, and design with an open‐source Molecular Software Library (MSL) (2012) (29)
Deep-Learning-Assisted Volume Visualization (2019) (29)
The democratization of cryo-EM (2016) (29)
HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1 (2013) (29)
Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants (2021) (29)
Ion-abrasion scanning electron microscopy reveals distorted liver mitochondrial morphology in murine methylmalonic acidemia. (2010) (28)
The SIV Surface Spike Imaged by Electron Tomography: One Leg or Three? (2006) (28)
Derivation of Neural Stem Cells from Human Adult Peripheral CD34+ Cells for an Autologous Model of Neuroinflammation (2013) (28)
Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate (2016) (27)
Automated 100-position specimen loader and image acquisition system for transmission electron microscopy. (2007) (27)
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation (2022) (27)
Single-Particle Cryo-Electron Microscopy (Cryo-EM): Progress, Challenges, and Perspectives for Further Improvement (2014) (26)
Catching HIV 'in the act' with 3D electron microscopy. (2013) (25)
Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer (2019) (25)
Extended polypeptide linkers establish the spatial architecture of a pyruvate dehydrogenase multienzyme complex. (2008) (23)
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging. (2012) (22)
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. (2019) (22)
Role of electrostatics in antibody-antigen association: anti-hen egg lysozyme/lysozyme complex (HyHEL-5/HEL). (1994) (22)
Ultraviolet-visible transient spectroscopy of bacteriorhodopsin mutants. Evidence for two forms of tyrosine-185----phenylalanine. (1990) (21)
An energy‐based conformer library for side chain optimization: Improved prediction and adjustable sampling (2012) (20)
Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake (2021) (19)
Biased Brownian dynamics for rate constant calculation. (2000) (18)
1.8 Å resolution structure of β-galactosidase with a 200 kV CRYO ARM electron microscope (2020) (18)
A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor (2020) (18)
Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome (2019) (17)
The cryo-EM revolution: fueling the next phase (2019) (17)
REGULARIZATION FOR INVERTING THE RADON TRANSFORM WITH WEDGE CONSIDERATION (2007) (16)
Glycan reactive anti-HIV-1 antibodies bind the SARS-CoV-2 spike protein but do not block viral entry (2021) (16)
Complexes of Neutralizing and Non-Neutralizing Affinity Matured Fabs with a Mimetic of the Internal Trimeric Coiled-Coil of HIV-1 gp41 (2013) (15)
Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis (2020) (14)
Studies of Rh1 metarhodopsin stabilization in wild-type Drosophila and in mutants lacking one or both arrestins. (1997) (14)
A paradigm shift in structural biology (2022) (14)
Cryo-EM Structure of the N501Y SARS-CoV-2 Spike Protein in Complex with a Potent Neutralizing Antibody (2021) (14)
Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging (2011) (14)
Cryo-EM of viruses and vaccine design (2016) (14)
SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization (2021) (13)
Semi-automated 3D segmentation of human skeletal muscle using Focused Ion Beam-Scanning Electron Microscopic images. (2019) (12)
Backbone dependency further improves side chain prediction efficiency in the Energy‐based Conformer Library (bEBL) (2014) (12)
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. (1992) (12)
Shape-Based Regularization of Electron Tomographic Reconstruction (2012) (12)
A coiled-coil-repeat protein 'Ccrp' in Bdellovibrio bacteriovorus prevents cellular indentation, but is not essential for vibroid cell morphology. (2010) (12)
Structure, activity and inhibition of human TMPRSS2, a protease implicated in SARS-CoV-2 activation (2021) (12)
Power Grid Protection of the Muscle Mitochondrial Reticulum (2018) (12)
The crystal structure of human GlnRS provides basis for the development of neurological disorders (2016) (12)
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase (2016) (11)
Reducing the flexibility of retinal restores a wild-type-like photocycle in bacteriorhodopsin mutants defective in protein-retinal coupling. (1997) (10)
Electron tomography of bacterial chemotaxis receptor assemblies. (2007) (9)
Site-specific 3D Imaging of Cells and Tissues Using DualBeam Technology (2004) (9)
A new approach for 3D segmentation of cellular tomograms obtained using three-dimensional electron microscopy (2004) (9)
Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells (2009) (8)
The residues Leu 93 and Asp 96 act independently in the bacteriorhodopsin photocycle: studies with the leu 93-->Ala, Asp 96-->Asn double mutant. (1996) (7)
AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation (2021) (7)
Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants (2022) (7)
Modulation of arrestin release in the light-driven regeneration of Rh1 Drosophila rhodopsin. (1996) (7)
Cryo-electron microscopy instrumentation and techniques for life sciences and materials science (2019) (6)
Microbiology catches the cryo-EM bug. (2018) (6)
Visualizing Cells and Humans in 3D: Biomedical Image Analysis at Nanometer and Meter Scales (2012) (5)
FROM GIGABYTES TO BYTES: AUTOMATED DENOISING AND FEATURE IDENTIFICATION IN ELECTRON TOMOGRAMS OF INTACT BACTERIAL CELLS (2007) (4)
Stoichiometry and absolute quantification of proteins (2007) (4)
COVID-19 and cryo-EM (2020) (4)
3D Imaging of Melanoma Cells Using Automated “Ion Abrasion Scanning Electron Microscopy” (2007) (3)
Electron Tomography : a Powerful Tool for 3 D Cellular Microscopy Technical refinements enable investigators to locate proteins inside cells and to anticipate tomographic reconstructions of bacteria (2003) (3)
Three-Dimensional Visualization of Viral Structure, Entry, and Replication Underlying the Spread of SARS-CoV-2 (2022) (3)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (3)
Residue Specific Radiation Damage of Protein Structures using High-Resolution Cryo-Electron Microscopy (2015) (3)
A template-propagation method for segmentation of filamentous structures in electron tomograms (2004) (3)
CLASSIFICATION, AVERAGING AND RECONSTRUCTION OF MACROMOLECULES IN ELECTRON TOMOGRAPHY (2007) (3)
Expression of Bacteriorhodopsin in Sf9 and COS-1 Cells (1997) (3)
CLASSIFICATION AND AVERAGING OF ELECTRON TOMOGRAPHY VOLUMES (2006) (2)
Comparison of side-chain dispersion in protein structures determined by cryo-EM and X-ray crystallography. (2021) (2)
Learning from Gobind Khorana: “The difficult we do today, the impossible tomorrow” (2022) (2)
Evidence for a long-lived 13-cis-containing intermediate in the photocycle of the Leu 93 → Ala bacteriorhodopsin mutant (1997) (2)
Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures (2020) (2)
Structure and Function of Icosahedral Pyruvate Dehydrogenase Complexes (2006) (1)
Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein (2023) (1)
Molecular Structures of Native HA Trimers on 2009 H1N1 Pandemic Influenza Virus Complexed with Neutralizing Antibodies (2013) (1)
Site-specific Automated 3D Imaging of Cells and Tissues Using a Dual-Beam Microscope (2005) (1)
Atom Probe Tomography of Mammalian Cells: Advances in Specimen Preparation (2010) (1)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (1)
Numerical computing of molecular electrostatics through boundary integral equations (1996) (1)
Imaging Cellular Architecture with 3D SEM (2016) (1)
1.8 Angstrom resolution structure of b-galactosidase with a 200 kV cryoARM electron microscope (2020) (1)
Resolution advances in cryo-EM enable application to drug discovery (2017) (1)
A structural mechanism for the generation of biased agonism in the epidermal growth factor receptor (2020) (1)
New insights into Raf regulation from structural analyses. (2021) (1)
Gigabytes to Bytes: Automated Denoising and Feature Extraction as Applied to the Analysis of HIV Architecture and Variability using Electron Tomography (2007) (1)
B-Raf:14-3-3 complex (2019) (0)
Conformational sampling in protein structure prediction (2014) (0)
Integration of deletion mutants of bovine rhodopsin into the membrane of the endoplasmic reticulum. (2000) (0)
PNAS Plus Significance Statements (2014) (0)
Table of Contents (1993) (0)
A machine learning based approach to improve sidechain optimization (2011) (0)
Conformational analysis of allyl halides from the calculation of indirect spin-spin coupling (1988) (0)
Author response: A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor (2021) (0)
Data Management Pipeline at the National Cryo-EM Facility (2020) (0)
Molecular structure for the HIV-1 gp120 trimer in the b12-bound state (2008) (0)
3D imaging of cells using electron tomography (2003) (0)
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (2021) (0)
Automated Data Collection with a Tecnai 12 Electron Microscope for Applications in Structural Biology (2001) (0)
Correction: Protein Conformational Changes in the Bacteriorhodopsin Photocycle: Comparison of Findings from Electron and X-Ray Crystallographic Analyses (2009) (0)
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex (2017) (0)
Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state II (2016) (0)
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain (2021) (0)
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 1) (2021) (0)
Cryo-EM structure of isocitrate dehydrogenase (IDH1) in inhibitor-bound state (2016) (0)
Cryo-EM Tomographic Analysis of a Universal Influenza Virus Vaccine Candidate (2017) (0)
Author response: Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs (2018) (0)
Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N (2017) (0)
Correction: Protein Conformational Changes in the Bacteriorhodopsin Photocycle: Comparison of Findings from Electron and X-Ray Crystallographic Analyses (2009) (0)
Molecular Structure of an Icosahedral Pyruvate Dehydrogenase Complex (2002) (0)
Localization of Small Ligands in a Metabolic Protein Complex using Cryo-Electron Microscopy (2015) (0)
Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains (2022) (0)
Structures of the Mg2+ Channel Cora in the Open State by Cryo Electron Microscopy (2016) (0)
Atomic Resolution Cryo-E M Structure of b-Galactosidase Graphical Abstract Highlights (2018) (0)
Automation of Tilt Pair Data Acquisition in Single Particle Cryo-Electron Microscopy (2013) (0)
DETERMINATION OF PROTEIN STRUCTURES IN SITU: ELECTRON TOMOGRAPHY OF INTACT VIRUSES AND CELLS (2007) (0)
There is no overkill in biochemistry (2012) (0)
CRYSTAL STRUCTURE OF NATIVE CONFORMATION OF BACTERIORHODOPSIN (2000) (0)
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain (2018) (0)
100 3D structure of native HIV-1 gp120 trimers and mechanisms of cellular entry (2009) (0)
Cells and Viruses at Molecular Resolution: From Structure to Mechanism (2010) (0)
Ion Beam Nanodissection for 3D Compositional Mapping of Mammalian Cells (2010) (0)
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome (2019) (0)
Automated methods for 3D Segmentation of Focused Ion Beam-Scanning Electron Microscopic Images (2019) (0)
Structural changes underlying proton pumping by Bacteriorhodopsin (1997) (0)
Single-particle Cryo-EM of Membrane Proteins - Success Stories and Current Challenges (2020) (0)
Cryo-EM structure of human p97 bound to UPCDC30245 inhibitor (2016) (0)
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 (2019) (0)
GroEL at sub-nanometer resolution by Constrained Single Particle Tomography (2012) (0)
Using cryo-EM to Untangle the Conformational Landscape of a Small Allosterically-Regulated Complex (2016) (0)
GluK2EM with 2S,4R-4-methylglutamate (2016) (0)
Rhodopsin-Gi complex (2018) (0)
Structural Studies on Glutamate Receptor Gating (2015) (0)
Computational Separation of Conformational Heterogeneity using Cryo-Electron Tomography and 3D Sub-Volume Averaging (2013) (0)
Molecular Architecture of Receptor Arrays in Intact E.coli Cells Determined Using Cryo-electron Tomography (2007) (0)
Author response: Building bridges between cellular and molecular structural biology (2017) (0)
Structure of trimeric HIV-1 BaL Env bound to VRC01 and VRC03 antibodies. (2012) (0)
Structure Determination of Small Macromolecular Complexes by Cryo-Electron Microscopy (2014) (0)
Structure of bovine glutamate dehydrogenase in the unliganded state (2016) (0)
Automated Workflows for Structure Determination by Single-Particle Cryo-EM at Sub-Nanometer Resolutions (2013) (0)
The NCI National Cryo-EM Facility (2019) (0)
IMAGING AND MODELING DYNAMIC MOLECULAR MACHINES IN BIOLOGY: APPLICATIONS TO HIV/AIDS AND CANCER (2008) (0)
Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state (2016) (0)
Molecular structures of icosahedral pyruvate dehydrogenase complexes from B stearothermophilus determined by cryo electron microscopy (2004) (0)
Faculty Opinions recommendation of Predataxis behavior in Myxococcus xanthus. (2008) (0)
Faculty Opinions recommendation of The Structure of calnexin, an ER chaperone involved in quality control of protein folding. (2002) (0)
The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha (2018) (0)
3D Imaging of Membrane Networks in a Bacterial Cell Using Electron Tomography (2003) (0)
Structural Studies of Trimeric SIV and HIV-1 Envelope Glycoproteins Using Cryo-Electron Tomography (2010) (0)
Cryo-EM structure of human p97 bound to ADP (2016) (0)
Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate (2014) (0)
Paradigm Shift in the Mechanism of HIV-1 Core Biogenesis (2015) (0)
CRYSTAL STRUCTURE OF CYTOPLASMICALLY OPEN CONFORMATION OF BACTERIORHODOPSIN (2000) (0)
Probing Buffer-Specific Effects on Nucleotide Binding to RecA using Difference Ftir (2015) (0)
Glutamate Receptor Desensitization Mediated by Changes in Quaternary Structure of the Ligand Binding Domain (2013) (0)
Glutamate dehydrogenase in complex with NADH and GTP, closed conformation (2016) (0)
Electron density map of GluA2em in complex with LY451646 and glutamate (2014) (0)
Glutamate dehydrogenase in complex with NADH, closed conformation (2016) (0)
Abstract CN08-03: 3-D electron microscopy in cellular and molecular imaging: Applications to cancer (2013) (0)
Introduction: Cryo-EM in Biology and Materials Research. (2022) (0)
Monkey Models Highlights from the Meeting on Nonhuman Primates in Aids Research Visualizing Hiv Profile: Sriram Subramaniam (2009) (0)
Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes (2017) (0)
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8 (2021) (0)
Plasmodium falciparum RhopH complex in soluble form (2021) (0)
Structure Ways & Means Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography (2012) (0)
Analysis of the spatial arrangement of bacterial chemotaxis receptors in E-coli using three-dimensional electron microscopy (2004) (0)
Automated, 100-Specimen Loading and Imaging System for Transmission Electron Microscopy (2006) (0)
The National Cryo-EM Facility at Frederick National Laboratory: Operational Procedures, Methods, and Outputs (2020) (0)
GluK2EM with LY466195 (2016) (0)
9 Å Structure of Trimeric HIV-1 Envelope Glycoprotein in an Activated State (2013) (0)
Cryo-EM at ACA 2022 (2022) (0)
Electron Tomography and Molecular Modeling Study of Chemoreceptor Organization (2010) (0)
Accelerating Discovery in 3D Microanalysis: Leveraging Open Source Software and Deskside High Performance Computing (2014) (0)
3D Imaging of Diatoms with Ion Abrasion Scanning Electron Microscopy (2008) (0)
Cryo-EM density map of GluA2em in complex with ZK200775 (2014) (0)
Single-Particle Cryo-EM Studies of a 200-kDa Magnesium Ion Channel Reveal Large Structural Changes Upon Gating (2016) (0)
D102 Molecular structures of trimeric HIV-1 and SIV envelope glycoproteins (2013) (0)
A central role for extended polypeptide linkers in establishing the spatial architecture of a pyruvate dehydrogenase complex (2007) (0)
Molecular structure for the HIV-1 gp120 trimer in the unliganded state (2008) (0)
Biochemical and structural analysis reveals the Neurofibromin (NF1) protein forms a high-affinity dimer (2019) (0)
Direct Imaging of Molecular Structures with Electron Microscopes (2015) (0)
There is no overkill in biochemistry (2012) (0)
Cryo-EM structure of glutamate dehydrogenase at 1.8 A resolution (2016) (0)
D-104 Cryo-EM of dynamic molecular assemblies (2017) (0)
Binding of Neutralizing Antibodies Results in Distinct Quaternary Conformations of Trimeric HIV-1 Envelope Glycoproteins (2013) (0)
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA (2017) (0)
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein (2018) (0)
Cryo-EM structure of the magnesium channel CorA in the closed symmetric magnesium-bound state (2016) (0)
Cryo-EM structure of nucleosome core particle (2019) (0)
Cryo-EM reveals disrupted human p97 allosteric activation by disease mutations and inhibitor binding (2021) (0)
Bridging the imaging gap in nanobiology with three-dimensional electron microscopy (2006) (0)
Faculty Opinions recommendation of Receptor-receptor coupling in bacterial chemotaxis: evidence for strongly coupled clusters. (2006) (0)
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 (2019) (0)
Cryo-EM structure of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome (2019) (0)
The National Cryo-EM Facility (2018) (0)
Glutamate dehydrogenase in complex with GTP (2016) (0)
Electron density map of GluA2em in complex with quisqualate and LY451646 (2014) (0)
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 2) (2021) (0)
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus (2015) (0)
Ultrastructure of the Gliding Bacterium Flavobacterium johnsoniae Revealed by Cryo-electron Tomography (2007) (0)
Author response: Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake (2020) (0)
Cryo-EM structure of human p97 bound to ATPgS (Conformation III) (2016) (0)
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10 (2017) (0)
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium (2019) (0)
Practical Tools for Effective Tracking of Titan Krios Usage Performance and Uptime (2013) (0)
Cryo-EM structure of isocitrate dehydrogenase (IDH1) (2016) (0)

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What Schools Are Affiliated With Sriram Subramaniam?

Sriram Subramaniam is affiliated with the following schools:

California Institute of Technology
University of British Columbia
University of Wisconsin–Madison
Rockefeller University
Massachusetts Institute of Technology
Stanford University
Johns Hopkins University
University of Illinois Urbana-Champaign