Stanley Fields

Q: What Schools Are Affiliated With Stanley Fields

Stanley Fields is affiliated with the following schools: University of California, Berkeley, University of Oxford, University of Washington, University of California, San Francisco, University of Cambridge

Stanley Fields 's AcademicInfluence.com Rankings

Stanley Fields

Biology

#2154

World Rank

#3457

Historical Rank

Biochemistry

#678

World Rank

#777

Historical Rank

biology Degrees

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Biology

Stanley Fields 's Degrees

PhD Biochemistry University of California, San Francisco
Bachelors Chemistry University of California, Berkeley

Why Is Stanley Fields Influential?

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According to Wikipedia, Stanley Fields is an American biologist best known for developing the yeast two hybrid method for identifying protein–protein interactions. He is currently a professor of Genome Sciences at the University of Washington and Howard Hughes Medical Institute Investigator, and serves as chair of the Department of Genome Sciences.

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Stanley Fields 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A novel genetic system to detect proteinprotein interactions (1989) (6214)
A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae (2000) (4897)
Comparative assessment of large-scale data sets of protein–protein interactions (2002) (2434)
The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. (1991) (1441)
A network of protein–protein interactions in yeast (2000) (1367)
Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients (2005) (1260)
A Three-Dimensional Model of the Yeast Genome (2010) (939)
Extension of chronological life span in yeast by decreased TOR pathway signaling. (2006) (931)
Protein-protein interactions: methods for detection and analysis (1995) (915)
Presence of a potent transcription activating sequence in the p53 protein. (1990) (793)
Substrate-specific Activation of Sirtuins by Resveratrol* (2005) (748)
Deep mutational scanning: a new style of protein science (2014) (724)
A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition Modules (2001) (721)
The two-hybrid system: an assay for protein-protein interactions. (1994) (659)
Global mapping of protein-DNA interactions in vivo by digital genomic footprinting (2009) (600)
Protein analysis on a proteomic scale (2003) (587)
A protein interaction network of the malaria parasite Plasmodium falciparum (2005) (550)
A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line (1997) (524)
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation (2013) (523)
A three-hybrid system to detect RNA-protein interactions in vivo. (1996) (514)
Elimination of false positives that arise in using the two-hybrid system. (1993) (497)
High Resolution Mapping of Protein Sequence–Function Relationships (2010) (458)
Two cellular proteins that bind to wild-type but not mutant p53. (1994) (446)
Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4 (2008) (443)
Sir2-Independent Life Span Extension by Calorie Restriction in Yeast (2004) (440)
A biochemical genomics approach for identifying genes by the activity of their products. (1999) (407)
Analyzing protein-protein interactions using two-hybrid system. (1995) (369)
A protein linkage map of Escherichia coli bacteriophage T7 (1996) (361)
A protein interaction map for cell polarity development (2001) (341)
Sequence of chicken ovalbumin mRNA (1978) (332)
Lifespan extension in Caenorhabditis elegans by complete removal of food (2006) (321)
Assigning function to yeast proteins by integration of technologies. (2003) (290)
Functional Genomics (1999) (290)
Genome-wide analysis of vaccinia virus protein-protein interactions. (2000) (286)
The minimum information required for reporting a molecular interaction experiment (MIMIx) (2007) (279)
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. (1994) (277)
Large-scale identification of yeast integral membrane protein interactions. (2005) (274)
Identification of mutations in p53 that affect its binding to SV40 large T antigen by using the yeast two‐hybrid system (1993) (248)
The yeast STE12 protein binds to the DNA sequence mediating pheromone induction. (1989) (247)
Massively Parallel Functional Analysis of BRCA1 RING Domain Variants (2015) (234)
Proteomics in Genomeland (2001) (233)
Engineering an allosteric transcription factor to respond to new ligands (2015) (227)
Stimulation of p53-mediated Transcriptional Activation by the p53-binding Proteins, 53BP1 and 53BP2* (1998) (207)
Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype (1981) (203)
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function (2012) (198)
Use of the two-hybrid system to identify the domain of p53 involved in oligomerization. (1993) (196)
Genetic selection of peptide inhibitors of biological pathways. (1999) (194)
A Novel, Evolutionarily Conserved Protein Phosphatase Complex Involved in Cisplatin Sensitivity*S (2005) (193)
Cloning of influenza cDNA ino M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein. (1980) (188)
Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein (2013) (183)
Structure of the neuraminidase gene in human influenza virus A/PR/8/34 (1981) (176)
Genes determining yeast replicative life span in a long-lived genetic background (2005) (167)
The Spatial Organization of Lipid Synthesis in the Yeast Saccharomyces cerevisiae Derived from Large Scale Green Fluorescent Protein Tagging and High Resolution Microscopy*S (2005) (163)
Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation. (1991) (158)
Protein-peptide interactions analyzed with the yeast two-hybrid system. (1995) (158)
The yeast two-hybrid system (1997) (155)
Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast (2016) (151)
Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment (2002) (147)
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis (2013) (144)
Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast (2013) (142)
Nucleotide sequences of influenza virus segments 1 and 3 reveal mosaic structure of a small viral RNA segment (1982) (141)
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase (2008) (140)
Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. (2003) (139)
The complete set of predicted genes from Saccharomyces cerevisiae in a readily usable form. (1997) (138)
Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. (2002) (137)
Altered transcription in yeast expressing expanded polyglutamine (2001) (132)
Deep learning of the regulatory grammar of yeast 5′ untranslated regions from 500,000 random sequences (2017) (132)
Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast (2005) (131)
Massively Parallel Single Amino Acid Mutagenesis (2014) (131)
Whither Model Organism Research? (2005) (131)
High-throughput screening for protein-protein interactions using two-hybrid assay. (2000) (128)
Measuring the activity of protein variants on a large scale using deep mutational scanning (2014) (126)
A general strategy to construct small molecule biosensors in eukaryotes (2015) (125)
Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction. (1990) (124)
The yeast STE12 product is required for expression of two sets of cell-type-specific genes (1985) (121)
High‐throughput two‐hybrid analysis (2005) (121)
A protein interaction map of the mitotic spindle. (2007) (115)
Enrich: software for analysis of protein function by enrichment and depletion of variants (2011) (111)
Analysis of membrane protein interactions using yeast-based technologies. (2002) (106)
Cell-type-specific transcription in yeast. (1991) (106)
Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana (2019) (104)
The Two-Hybrid System to Detect Protein-Protein Interactions (1993) (100)
Pheromone response in yeast. (1990) (97)
A Facile Method for High-throughput Co-expression of Protein Pairs*S (2004) (95)
Dimensionality reduction by UMAP to visualize physical and genetic interactions (2019) (93)
Whole-genome sequencing of a laboratory-evolved yeast strain (2010) (93)
The structure of the gene encoding the nucleoprotein of human influenza virus A/PR/8/34. (1981) (92)
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation (2006) (89)
Networking proteins in yeast (2001) (86)
Properties of the DNA-binding domain of the Saccharomyces cerevisiae STE12 protein (1991) (86)
Yeast STE7, STE11, and STE12 genes are required for expression of cell-type-specific genes (1988) (85)
A yeast sensor of ligand binding (2001) (84)
Coupling of cell identity to signal response in yeast: interaction between the alpha 1 and STE12 proteins. (1993) (83)
A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function. (2018) (82)
Hepatitis C Virus 3′X Region Interacts with Human Ribosomal Proteins (2001) (81)
The use of synthetic oligodeoxynucleotide primers in cloning and sequencing segment of 8 influenza virus (A/PR/8/34). (1981) (80)
Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana. (2019) (77)
Regulation by the yeast mating-type locus of STE12, a gene required for cell-type-specific expression (1987) (76)
Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome. (2001) (74)
The future is function (1997) (72)
Comment on "HST2 Mediates SIR2-Independent Life-Span Extension by Calorie Restriction" (2006) (71)
Quantitative Genome-Wide Analysis of Yeast Deletion Strain Sensitivities to Oxidative and Chemical Stress (2004) (68)
High-throughput Analysis of in vivo Protein Stability* (2013) (67)
The yeast G protein alpha subunit Gpa1 transmits a signal through an RNA binding effector protein Scp160. (2003) (66)
Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2 (1994) (66)
Chl4p and iml3p are two new members of the budding yeast outer kinetochore. (2003) (64)
Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p (1997) (63)
Wide Variation in Antibiotic Resistance Proteins Identified by Functional Metagenomic Screening of a Soil DNA Library (2012) (63)
Binding specificity of Toll‐like receptor cytoplasmic domains (2006) (62)
Identification of RNAs that bind to a specific protein using the yeast three-hybrid system. (1999) (62)
Nucleotide-sequence heterogeneity and sequence rearrangements in influenza virus cDNA. (1981) (62)
Functional domains of the yeast STE12 protein, a pheromone-responsive transcriptional activator (1993) (61)
A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications (2004) (61)
The yeast two-hybrid assay: still finding connections after 25 years (2014) (60)
Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins (2006) (60)
The yeast two-hybrid system: prospects for protein linkage maps. (1996) (54)
Intrinsic tethering activity of endosomal Rab proteins (2011) (53)
Capture and sequence analysis of RNAs with terminal 2',3'-cyclic phosphates. (2010) (53)
Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis (2014) (52)
Lethal combinations (2003) (52)
Nucleotide sequence of human influenza A/PR/8/34 segment 2. (1982) (51)
Cell biology. Whither model organism research? (2005) (51)
Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19 (2011) (51)
Regulation of Stress Response Signaling by the N-terminal Dishevelled/EGL-10/Pleckstrin Domain of Sst2, a Regulator of G Protein Signaling in Saccharomyces cerevisiae * (2002) (50)
Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint. (2003) (49)
Proteomics. Proteomics in genomeland. (2001) (48)
Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins (2008) (46)
The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution (2020) (46)
Sites of ubiquitin attachment in Saccharomyces cerevisiae (2012) (46)
Yeast three-hybrid system to detect and analyze interactions between RNA and protein. (1999) (44)
A genome-wide 3C-method for characterizing the three-dimensional architectures of genomes. (2012) (44)
A pooling-deconvolution strategy for biological network elucidation (2006) (44)
Engineering allostery. (2014) (43)
Interactive learning: Lessons from two hybrids over two decades (2009) (42)
Genome-wide identification of spliced introns using a tiling microarray. (2007) (42)
Engineering A-kinase Anchoring Protein (AKAP)-selective Regulatory Subunits of Protein Kinase A (PKA) through Structure-based Phage Selection* (2013) (41)
Structural genomics of pathogenic protozoa: an overview. (2008) (39)
Synthetic promoter designs enabled by a comprehensive analysis of plant core promoters (2021) (38)
Phermone response in yeast (1990) (37)
Zds2p Regulates Swe1p-dependent Polarized Cell Growth in Saccharomyces cerevisiae via a Novel Cdc55p Interaction Domain (2010) (36)
A TSC22-like motif defines a novel antiapoptotic protein family (2008) (35)
The Spindle Pole Body Assembly Component Mps3p/Nep98p Functions in Sister Chromatid Cohesion* (2004) (34)
Biochemical genomics approach to map activities to genes. (2002) (32)
High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection. (2010) (31)
The interplay of biology and technology (2001) (31)
Site-Seeing by Sequencing (2007) (30)
The Two-Hybrid System (2001) (29)
Caspase‐3 inhibits growth in Saccharomyces cerevisiae without causing cell death 1 (1999) (28)
The structure of two subgenomic RNAs from human influenza virus A/PR/8/34. (1981) (28)
Combining Natural Sequence Variation with High Throughput Mutational Data to Reveal Protein Interaction Sites (2015) (28)
Functional Analysis of BARD1 Missense Variants in Homology‐Directed Repair of DNA Double Strand Breaks (2015) (27)
A Genome-wide Screen for Site-specific DNA-binding Proteins* (2002) (26)
A homolog of lariat-debranching enzyme modulates turnover of branched RNA (2014) (26)
Complex Relationships between Chromatin Accessibility, Sequence Divergence, and Gene Expression in Arabidopsis thaliana (2018) (26)
Identification of Plant Enhancers and Their Constituent Elements by STARR-seq in Tobacco Leaves[OPEN] (2020) (25)
Selection of yeast strains with enhanced expression of Plasmodium falciparum proteins. (2009) (24)
Deep Mutational Scanning: A Highly Parallel Method to Measure the Effects of Mutation on Protein Function. (2015) (24)
Molecular biology. Site-seeing by sequencing. (2007) (23)
Yeast three-hybrid system to detect and analyze RNA-protein interactions. (2000) (23)
Genome-Wide Analysis of Nascent Transcription in Saccharomyces cerevisiae (2011) (22)
A tetO Toolkit To Alter Expression of Genes in Saccharomyces cerevisiae. (2015) (20)
Massively Parallel Genetics (2016) (20)
Protein Interaction Analysis of Senataxin and the ALS4 L389S Mutant Yields Insights into Senataxin Post-Translational Modification and Uncovers Mutant-Specific Binding with a Brain Cytoplasmic RNA-Encoded Peptide (2013) (20)
Conditional accumulation of toxic tRNAs to cause amino acid misincorporation (2018) (20)
Comprehensive Analysis of the SUL1 Promoter of Saccharomyces cerevisiae (2016) (20)
Array-based methods for identifying protein-protein and protein-nucleic acid interactions. (2002) (19)
Using the yeast three-hybrid system to detect and analyze RNA-protein interactions. (2000) (19)
Engineered Biosensors from Dimeric Ligand-Binding Domains. (2018) (18)
Dissociation of transcriptional activation and oncogenic transformation by v-Myb. (1995) (18)
Suppression of statin effectiveness by copper and zinc in yeast and human cells. (2011) (17)
Global analysis of RNA oxidation in Saccharomyces cerevisiae. (2012) (17)
Hph1 and Hph2 Are Novel Components of the Sec63/Sec62 Posttranslational Translocation Complex That Aid in Vacuolar Proton ATPase Biogenesis (2010) (17)
Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator Ste12p by mutations at the amino‐terminus (2000) (15)
The role of functional data in interpreting the effects of genetic variation (2015) (15)
A Biosensor Strategy for E. coli Based on Ligand-Dependent Stabilization. (2018) (15)
High-throughput identification of dominant negative polypeptides in yeast (2018) (14)
The pheromone signal pathway inSaccharomyces cerevisiae (1992) (13)
Preferences in a trait decision determined by transcription factor variants (2018) (12)
The two-hybrid system. A personal view. (2001) (12)
Developmental and conditional dynamics of gene expression in single root cells of A. thaliana (2018) (11)
Dynamics of gene expression in single root cells ofA. thaliana (2018) (11)
Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA (2018) (11)
Identification of putative Plasmodium falciparum mefloquine resistance genes. (2005) (11)
A Massively Parallel Fluorescence Assay to Characterize the Effects of Synonymous Mutations on TP53 Expression (2017) (10)
Grass-roots genomics (2000) (9)
Forcing interactions as a genetic screen to identify proteins that exert a defined activity. (2005) (8)
Distinct patterns of mutational sensitivity for λ resistance and maltodextrin transport in Escherichia coli LamB (2020) (7)
Deep Mutational Scanning: Calculating Enrichment Scores for Protein Variants from DNA Sequencing Output Files. (2015) (6)
MaveRegistry: a collaboration platform for multiplexed assays of variant effect (2020) (6)
AKAP-selective regulatory subunits of PKA through structure-based phage selection (2013) (6)
A densely overlapping gene fragmentation approach improves yeast two-hybrid screens for Plasmodium falciparum proteins. (2011) (6)
Deep Mutational Scanning: Library Construction, Functional Selection, and High-Throughput Sequencing. (2015) (5)
Genomics. A crisis in postgenomic nomenclature. (2002) (5)
A Crisis in Postgenomic Nomenclature (2002) (5)
Balance between promiscuity and specificity in phage λ host range (2020) (5)
The PDZ domain as you like it (1999) (4)
Expanding the binding specificity for RNA recognition by a PUF domain (2021) (4)
Regulatory DNA in A. thaliana can tolerate high levels of sequence divergence (2017) (4)
A TSC 22-like motif defines a novel anti-apoptotic protein family (2008) (3)
Stanley Fields phosphates-cyclic ′ , 3 ′ Capture and sequence analysis of RNAs with terminal 2 Material Supplemental (2010) (3)
Binding and Regulation of Transcription by Yeast Ste12 Variants To Drive Mating and Invasion Phenotypes (2019) (3)
Correction: Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19 (2011) (3)
Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin. (2022) (3)
Would Fred Sanger Get Funded Today? (2014) (3)
Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress: Research Articles (2004) (3)
A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function (2018) (3)
Proteome-wide identification of amino acid substitutions deleterious for protein function (2022) (3)
Corrigendum: Massively parallel single-amino-acid mutagenesis (2017) (2)
Positioning a medical school for modern biomedical research: the department of genome sciences at the University of Washington School of Medicine. (2006) (2)
Genetic Twists of Fate (2010) (2)
Phosphorylation and ubiquitylation crosstalk in protein degradation (2013) (2)
INFLUENZA VIRUS A/PR/8/34 GENES: SEQUENCING BY A SHOTGUN APPROACH (1981) (2)
Trait specificity mediated by alternative DNA-binding preferences of a single transcription factor in yeast (2017) (2)
Binding and Regulation of Transcription by Yeast Ste12 Variants To Drive Mating and Invasion Phenotypes. (2020) (2)
THE HAEMAGGLUTININ GENE OF INFLUENZA A/PR/8/34 (1981) (1)
Effects of sequence motifs in the yeast 3′ untranslated region determined from massively parallel assays of random sequences (2021) (1)
Effi cient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase (2008) (1)
Library Metagenomic Screening of a Soil DNA Proteins Identified by Functional Wide Variation in Antibiotic Resistance (2012) (1)
Balance between mutually exclusive traits shifted by variants of a yeast transcription factor (2018) (1)
Effects of sequence motifs in the yeast 3′ untranslated region determined from massively parallel assays of random sequences (2021) (1)
Nucleotide sequence heterogeneity and sequence rearrangements in influenza virus complementary dna (1981) (1)
Mapping functional regions of essential bacterial proteins with dominant-negative protein fragments (2022) (1)
Transcriptional re-wiring by mutation of the yeast Hsf1 oligomerization domain (2020) (1)
deletion collection Saccharomyces cerevisiae High-throughput profiling of amino acids in strains of the Material Supplemental (2010) (0)
Large-scale Protein Fitness Data Reveal Fundamental Protein Properties (2012) (0)
Author's Reply (2006) (0)
Dimensionality reduction by UMAP to visualize physical and genetic interactions (2020) (0)
Stress Response Signaling by Sst 2 22157 (2002) (0)
ArticleThe Yeast G Protein Subunit Gpa 1 Transmits a Signal through an RNA Binding Effector Protein Scp (2003) (0)
in cisplatin sensitivity (2005) (0)
The ste12 protein of saccharomyces cerevisiae contains a pheromone inducible transcription activation domain (1990) (0)
Structure-based Phage Selection Protein Kinase A ( PKA ) through ( AKAP )-selective Regulatory Subunits of Engineering A-kinase Anchoring Protein Signal Transduction : (2013) (0)
phenotypic diversity in budding yeast Integrative phenomics reveals insight into the structure of Material Supplemental (2013) (0)
CHAPTER 175 – Peptide Recognition Module Networks: Combining Phage Display with Two-Hybrid Analysis to Define Protein-Protein Interactions (2003) (0)
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase (2011) (0)
to rapid tRNA decay by high-throughput in vivo analysis Identification of the determinants of tRNA function and susceptibility Material (2014) (0)
Approaches to Analyze Protein Interactions (2002) (0)
Proteomics and genomics Presidential preference, protein purpose (2001) (0)
High-throughput Analysis of in vivo Protein Stability*□S (2013) (0)
Mapping functional regions of essential bacterial proteins with dominant-negative protein fragments. (2023) (0)
P1) Technology Development in a Multidisciplinary Center (2012) (0)
Molecular to Global Perspectives REDISCOVERING BIOLOGY If DNA is the genetic blueprint then what is the proteome ? (0)
Stanley Fields microarray Genome-wide identification of spliced introns using a tiling data (2007) (0)
High-throughput identification of dominant negative polypeptides in yeast (2019) (0)
4-11-1995 Protein-Peptide Interactions Analyzed with the Yeast Two-Hybrid System (2019) (0)
Regulation bytheYeastMating-Type LocusofSTE12, a Gene Required forCell-Type-Specific Expression (1987) (0)
Two-hybrid and Related Systems (2001) (0)
Publisher Correction: Expanding the binding specificity for RNA recognition by a PUF domain (2022) (0)

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