Stephanie Constant
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American science administrator
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Stephanie Constant's Degrees
- PhD Biochemistry Stanford University
Why Is Stephanie Constant Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephanie L. Constant is an American immunologist and science administrator. She was an associate professor at George Washington University and a scientific review officer at National Heart, Lung, and Blood Institute before becoming chief of the National Institute of General Medical Sciences Office of Scientific Review in 2017.
Stephanie Constant's Published Works
Published Works
- Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. (1997) (1666)
- Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells (1995) (745)
- Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 Differentiation (2002) (544)
- B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo. (1995) (340)
- Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. (1997) (301)
- Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment (2008) (263)
- MyD88-dependent induction of allergic Th2 responses to intranasal antigen. (2005) (251)
- B lymphocytes as antigen-presenting cells for CD4+ T cell priming in vivo. (1999) (232)
- Extracellular Cyclophilins Contribute to the Regulation of Inflammatory Responses1 (2005) (224)
- Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. (2002) (209)
- Cyclophilin–CD147 interactions: a new target for anti-inflammatory therapeutics (2010) (198)
- Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding. (1997) (186)
- Internalization of Leishmania mexicana Complex Amastigotes via the Fc Receptor Is Required to Sustain Infection in Murine Cutaneous Leishmaniasis (2000) (183)
- Role of dendritic cells in the priming of CD4+ T lymphocytes to peptide antigen in vivo. (1993) (182)
- Pivotal Advance: Eosinophil infiltration of solid tumors is an early and persistent inflammatory host response (2006) (174)
- Dealing with the family: CD147 interactions with cyclophilins (2006) (169)
- Peptide and protein antigens require distinct antigen-presenting cell subsets for the priming of CD4+ T cells. (1995) (142)
- Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A (2007) (113)
- Site of antigen delivery can influence T cell priming: pulmonary environment promotes preferential Th2‐type differentiation (2000) (110)
- CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR. (1998) (97)
- Targeting the chemotactic function of CD147 reduces collagen‐induced arthritis (2009) (93)
- Immunobiology of hookworm infection. (2005) (92)
- JNK1 Is Required for T Cell-Mediated Immunity Against Leishmania major Infection1 (2000) (81)
- Novel Approach to Inhibit Asthma-Mediated Lung Inflammation Using Anti-CD147 Intervention1 (2006) (81)
- Lung Inflammation, Injury, and Proliferative Response after Repetitive Particulate Hexavalent Chromium Exposure (2009) (76)
- A Secreted Protein from the Human Hookworm Necator americanus Binds Selectively to NK Cells and Induces IFN-γ Production (2004) (71)
- Lung injury, inflammation and Akt signaling following inhalation of particulate hexavalent chromium. (2009) (71)
- Cutting Edge: Genetic Variation Influences FcεRI-Induced Mast Cell Activation and Allergic Responses1 (2007) (70)
- Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro. (2008) (65)
- Isoform-specific inhibition of cyclophilins. (2009) (61)
- A Cell-Impermeable Cyclosporine A Derivative Reduces Pathology in a Mouse Model of Allergic Lung Inflammation (2010) (52)
- Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses. (2007) (44)
- Mechanism of Transforming Growth Factor (cid:2) –induced Inhibition of T Helper Type 1 Differentiation (2002) (43)
- Leishmania pifanoi Pathogenesis: Selective Lack of a Local Cutaneous Response in the Absence of Circulating Antibody (2002) (42)
- A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins. (2010) (42)
- Liver proteomics for therapeutic drug discovery: Inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure* (2007) (41)
- Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology. (2012) (36)
- In vivo lymphocyte responses in the draining lymph nodes of mice exposed to Schistosoma mansoni: preferential proliferation of T cells is central to the induction of protective immunity. (1992) (31)
- Are primed CD4+ T lymphocytes different from unprimed cells? (1994) (31)
- Deficient inflammatory response to UV radiation in neonatal mice (2007) (30)
- IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro (2012) (28)
- Cyclophilin A cooperates with MIP-2 to augment neutrophil migration (2011) (27)
- Extracellular Cyclophilin Levels Associate with Parameters of Asthma in Phenotypic Clusters (2011) (26)
- Phenotypic analysis of the cellular responses in regional lymphoid organs of mice vaccinated against Schistosoma mansoni (1990) (24)
- Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation. (2011) (22)
- Cyclophilin – CD 147 interactions : a new target for anti-inflammatory therapeuticscei (2010) (21)
- CD4 and CD45 regulate qualitatively distinct patterns of calcium mobilization in individual CD4+ T cells (1995) (21)
- Binding of Excreted and/or Secreted Products of Adult Hookworms to Human NK Cells in Necator americanus-Infected Individuals from Brazil (2008) (21)
- VBP15, a Glucocorticoid Analogue, Is Effective at Reducing Allergic Lung Inflammation in Mice (2013) (20)
- The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis (2011) (18)
- A Nonproliferating Parvovirus Vaccine Vector Elicits Sustained, Protective Humoral Immunity following a Single Intravenous or Intranasal Inoculation (2004) (9)
- Abstract 5456: Potential role of nitric oxide in chromium-induced lung carcinogenesis (2012) (4)
- CYCLOPHILIN A IS A MEDIATOR OF PARACETAMOL-INDUCED LIVER INJURY (2009) (2)
- B Lymphocytes as Antigen-Presenting Cells (1999) (1)
- Abstract 5734: Role of the inflammasome complex in Cr(VI)-induced lung injury and inflammation (2012) (1)
- Differenzielle Hemmung extra‐ und intrazellulärer Cyclophiline durch Cyclosporinderivate (2010) (1)
- Targeting the function of extracellular cyclophilins as a novel approach for the treatment of Rheumatoid Arthritis (RA). (35.13) (2010) (0)
- The role of cyclophilins in regulating leukocyte recruitment in chronic allergic asthma. (35.14) (2010) (0)
- Role of cyclophilins in acute allergic asthma (2008) (0)
- Hookworm NK cell binding protein: identifying the 80kDa protein in Necator americanus excretory/secretory products (2008) (0)
- Drug-peptide construct for extracellular accumulation (2008) (0)
- New cyclosporine derivatives (2011) (0)
- γ Selectively to NK Cells and Induces IFN- Hookworm Necator americanus Binds A Secreted Protein from the Human (2013) (0)
- Cyclophilin A and MIP‐2 synergize to promote greater neutrophil migration (2008) (0)
- Effect of IL-4 and IL-13 on the chemotaxis of mouse eosinophils (38.2) (2007) (0)
- Recruitment Adhesion Inhibitor , Limits Inflammatory Cell Del-1 , an Endogenous Leukocyte-Endothelial (2009) (0)
- Cyclophilin A synergizes with MIP-2 to augment pro-inflammatory leukocyte recruitment (140.5) (2010) (0)
- Peptides of Different Affinities for the TCR Differentiation Following Stimulation with CD4 Regulation of TCR Signaling and T Cell (1998) (0)
- A Cell-impermeable Derivative Of Cyclosporine A Reduces Disease Pathology In A Mouse Model Of Allergic Asthma (2010) (0)
- Model of Allergic Lung Inflammation Derivative Reduces Pathology in a Mouse A Cell-Impermeable Cyclosporine A (2010) (0)
- Infection Leishmania major Immunity Against JNK 1 Is Required for T Cell-Mediated (2000) (0)
- Differentiat ion o f Naive CD 4 + T Cells (2003) (0)
- Blocking extracellular cyclophilin-CD147 interactions inhibits asthma-mediated lung inflammation (2006) (0)
- Contribution of Extracellular Cyclophilins to Leukocyte Recruitment in Acute Allergic Asthma (2009) (0)
- The induction of protective immunity to Schistosoma mansoni in mice : in vivo lymphocyte responses in the draining lymph nodes. (1991) (0)
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