Stephen Altschul
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Mathematician
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Stephen Altschulmathematics Degrees
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#3610
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Mathematics
Stephen Altschul's Degrees
- PhD Mathematics Stanford University
Why Is Stephen Altschul Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephen Frank Altschul is an American mathematician who has designed algorithms that are used in the field of bioinformatics . Altschul is the co-author of the BLAST algorithm used for sequence analysis of proteins and nucleotides.
Stephen Altschul's Published Works
Published Works
- Basic local alignment search tool. (1990) (83318)
- Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. (1997) (51960)
- Basic local alignment search tool. Journal of Molecular Biology (1990) (2131)
- Detecting subtle sequence signals: a Gibbs sampling strategy for multiple alignment. (1993) (2028)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences (2002) (1846)
- Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes. (1990) (1592)
- Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. (2001) (1287)
- Protein database searches using compositionally adjusted substitution matrices (2005) (973)
- A workbench for multiple alignment construction and analysis (1991) (964)
- Issues in searching molecular sequence databases (1994) (794)
- A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins (1997) (789)
- Local alignment statistics. (1996) (773)
- Amino acid substitution matrices from an information theoretic perspective (1991) (678)
- Iterated profile searches with PSI-BLAST--a tool for discovery in protein databases. (1998) (671)
- Domain enhanced lookup time accelerated BLAST (2012) (664)
- A tool for multiple sequence alignment. (1989) (538)
- Protein database searches for multiple alignments. (1990) (472)
- A public database for gene expression in human cancers. (1999) (447)
- SAGEmap: a public gene expression resource. (2000) (440)
- Applications and statistics for multiple high-scoring segments in molecular sequences. (1993) (417)
- Composition-based statistics and translated nucleotide searches: Improving the TBLASTN module of BLAST (2006) (377)
- Protein sequence similarity searches using patterns as seeds. (1998) (322)
- IMPALA: matching a protein sequence against a collection of PSI-BLAST-constructed position-specific score matrices (1999) (313)
- Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks. (1994) (294)
- BRCA1 protein products ... Functional motifs... (1996) (217)
- The estimation of statistical parameters for local alignment score distributions. (2001) (188)
- Weights for data related by a tree. (1989) (185)
- Significance of nucleotide sequence alignments: a method for random sequence permutation that preserves dinucleotide and codon usage. (1985) (181)
- Optimal sequence alignment using affine gap costs. (1986) (180)
- Improved Sensitivity of Nucleic Acid Database Searches Using Application-Specific Scoring Matrices (1991) (166)
- Statistics of sequence-structure threading. (1995) (161)
- Gap costs for multiple sequence alignment. (1989) (155)
- Eukaryotic translation elongation factor 1γ contains a glutathione transferase domain—Study of a diverse, ancient protein super family using motif search and structural modeling (1994) (153)
- Differences in the RNA binding sites of iron regulatory proteins and potential target diversity. (1996) (134)
- PSI-BLAST pseudocounts and the minimum description length principle (2008) (128)
- Characterization of Gene Expression in Resting and Activated Mast Cells (1998) (120)
- The construction of amino acid substitution matrices for the comparison of proteins with non-standard compositions (2005) (99)
- The compositional adjustment of amino acid substitution matrices (2003) (92)
- A protein alignment scoring system sensitive at all evolutionary distances (1993) (92)
- Generalized affine gap costs for protein sequence alignment (1998) (84)
- Statistical methods and insights for protein and DNA sequences. (1991) (75)
- Optimal sequence alignment using affine gap costs (1986) (72)
- Evaluating the Statistical Significance of Multiple Distinct Local Alignments (1997) (62)
- The Construction and Use of Log-Odds Substitution Scores for Multiple Sequence Alignment (2010) (60)
- Retrieval accuracy, statistical significance and compositional similarity in protein sequence database searches (2006) (58)
- A nonlinear measure of subalignment similarity and its significance levels. (1986) (54)
- Locally optimal subalignments using nonlinear similarity functions. (1986) (51)
- BioSCAN: a VLSI-based system for biosequence analysis (1991) (40)
- Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs. (2003) (34)
- Dirichlet Mixtures, the Dirichlet Process, and the Structure of Protein Space (2013) (31)
- The anatomy of successful computational biology software (2013) (29)
- A structure-based method for protein sequence alignment (2005) (26)
- Equal animals (1990) (23)
- Significance levels for biological sequence comparison using non-linear similarity functions. (1988) (19)
- Bayesian Top-Down Protein Sequence Alignment with Inferred Position-Specific Gap Penalties (2016) (17)
- An assessment of substitution scores for protein profile-profile comparison (2011) (14)
- Outlier detection in BLAST hits (2018) (13)
- Inferring joint sequence-structural determinants of protein functional specificity (2018) (12)
- Log-odds sequence logos (2015) (11)
- Compositional Adjustment of Dirichlet Mixture Priors (2010) (10)
- Deep Analysis of Residue Constraints (DARC): identifying determinants of protein functional specificity (2020) (8)
- On the Inference of Dirichlet Mixture Priors for Protein Sequence Comparison (2011) (8)
- Leaf Pairs and Tree Dissections (1989) (8)
- The effectiveness of position- and composition-specific gap costs for protein similarity searches (2008) (8)
- Fundamentals of database searching (1998) (7)
- Initial Cluster Analysis (2017) (7)
- Evolutionary trees for the genus Bordetella (1989) (7)
- A Gibbs sampler for the detection of subtle motifs in multiple sequences (1994) (6)
- Statistical investigations of protein residue direct couplings (2018) (6)
- Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations (2016) (5)
- The Complexity of the Dirichlet Model for Multiple Alignment Data (2011) (4)
- Aspects of biological sequence comparison (1987) (2)
- Erratum: The anatomy of successful computational biology software (2014) (1)
- Significance of dna or rna sequence alignments random permutation methods that preserve dinucleotide trinucleotide or dinucleotide and codon usage (1985) (1)
- Significance levels for biological sequence comparison using non-linear similarity functions (1988) (1)
- Domain enhanced lookup time accelerated BLAST (2012) (1)
- Local Alignment (with Affine Gap Weights) (2008) (1)
- A nonlinear measure of subalignment similarity and its significance levels (1986) (1)
- Column Scores (2011) (0)
- Deep Analysis of Residue Constraints (DARC): identifying determinants of protein functional specificity (2020) (0)
- Detecting SubtleSequence Signals:.A Gibbs Sampling StrategyforMultiple Alignment (1993) (0)
- SCORING SYSTEMS FOR MACROMOLECULAR SEQUENCE COMPARISON (1993) (0)
- Author response: Inferring joint sequence-structural determinants of protein functional specificity (2017) (0)
- Fundamentals of database searching Aligning novel sequences (2014) (0)
- Outlier detection in BLAST hits (2018) (0)
- Locally optimal subalignments using nonlinear similarity functions (1986) (0)
- eCOMPASS: evaluative comparison of multiple protein alignments by statistical score (2021) (0)
- Parallelizing and Analyzing the Behavior of Sequence Alignment Algorithm on a Cluster of Workstations for Large Datasets (2015) (0)
- 23 : 2 Outlier Detection in BLAST Hits 1 Introduction (2017) (0)
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Other Resources About Stephen Altschul
What Schools Are Affiliated With Stephen Altschul?
Stephen Altschul is affiliated with the following schools: