Stephen G. Young
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Researcher ORCID ID = 0000-0001-7270-3176
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(Suggest an Edit or Addition)Stephen G. Young's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. (1999) (704)
- Probucol inhibits oxidative modification of low density lipoprotein. (1986) (614)
- The Knockout Mouse Project (2004) (574)
- Lamins A and C but Not Lamin B1 Regulate Nuclear Mechanics* (2006) (572)
- ESCRT-III Dysfunction Causes Autophagosome Accumulation and Neurodegeneration (2007) (483)
- Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect (2002) (437)
- Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. (2007) (435)
- Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. (1999) (409)
- Recent Progress in Understanding Apolipoprotein B (1990) (383)
- Lamin B1 is required for mouse development and nuclear integrity. (2004) (367)
- Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin (1996) (336)
- Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. (1991) (319)
- GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. (2010) (316)
- A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria (2006) (316)
- Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation. (2005) (297)
- Biochemistry and pathophysiology of intravascular and intracellular lipolysis. (2013) (291)
- Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes. (2005) (284)
- A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation. (2006) (278)
- Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. (2011) (272)
- BayGenomics: a resource of insertional mutations in mouse embryonic stem cells (2003) (256)
- Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice. (1997) (253)
- Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. (1995) (252)
- Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. (1998) (252)
- Laminopathies and the long strange trip from basic cell biology to therapy. (2009) (246)
- Prelamin A and lamin A appear to be dispensable in the nuclear lamina. (2006) (246)
- Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). (1993) (238)
- Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. (1995) (238)
- Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques (2011) (234)
- Disruption of the Phosphatidylserine Decarboxylase Gene in Mice Causes Embryonic Lethality and Mitochondrial Defects* (2005) (215)
- Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. (1995) (210)
- Calcific Aortic Valve Stenosis in Old Hypercholesterolemic Mice (2006) (206)
- A public gene trap resource for mouse functional genomics (2004) (203)
- Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice (2004) (203)
- Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis. (2005) (203)
- Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA (2012) (198)
- Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons (2011) (194)
- Disruption of the Mouse Rce1 Gene Results in Defective Ras Processing and Mislocalization of Ras within Cells* (1999) (178)
- A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet (1998) (174)
- CD1d function is regulated by microsomal triglyceride transfer protein (2004) (171)
- A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. (2005) (169)
- Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. (2010) (169)
- Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases. (2005) (167)
- Cloning and Characterization of a Mammalian Prenyl Protein-specific Protease* (1999) (162)
- Isoprenylcysteine Carboxyl Methyltransferase Deficiency in Mice* (2001) (162)
- Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency (2010) (160)
- Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. (2004) (160)
- Molecular Basis of the Interaction between Plasma Platelet-activating Factor Acetylhydrolase and Low Density Lipoprotein* (1999) (159)
- Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice. (1998) (157)
- Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48 (*) (1996) (156)
- Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase (2009) (155)
- Targeted Inactivation of the Isoprenylcysteine Carboxyl Methyltransferase Gene Causes Mislocalization of K-Ras in Mammalian Cells* (2000) (153)
- The ABCs of cholesterol efflux (1999) (148)
- Mouse models of the laminopathies. (2007) (147)
- A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. (1996) (147)
- Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated. (2008) (146)
- Lowering Plasma Cholesterol Levels Halts Progression of Aortic Valve Disease in Mice (2009) (146)
- Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate (2003) (143)
- Lipoprotein size and atherosclerosis susceptibility in Apoe(-/-) and Ldlr(-/-) mice. (2001) (141)
- Expression of carboxyl-terminally truncated forms of human apolipoprotein B in rat hepatoma cells. Evidence that the length of apolipoprotein B has a major effect on the buoyant density of the secreted lipoproteins. (1991) (141)
- Chylomicron-sized lipid particles are formed in the setting of apolipoprotein B deficiency. (1998) (141)
- Absence of the CAAX Endoprotease Rce1: Effects on Cell Growth and Transformation (2002) (141)
- Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi. (2002) (138)
- Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100. (1996) (138)
- Prelamin A Farnesylation and Progeroid Syndromes* (2006) (137)
- Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells (2018) (136)
- The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse (2005) (133)
- Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. (2013) (130)
- Eliminating Atherogenesis in Mice by Switching Off Hepatic Lipoprotein Secretion (2003) (130)
- AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase* (2008) (129)
- Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins. (1998) (129)
- Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesitys⃞s⃞ The online version of this article (available at http://www.jlr.org) contains additional table and figure. Published, JLR Papers in Press, January 25, 2006. (2006) (129)
- The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. (2014) (129)
- Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion (2015) (128)
- Agpat6—a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium Published, JLR Papers in Press, January 31, 2006. (2006) (127)
- The posttranslational processing of prelamin A and disease. (2009) (126)
- Apo B100-containing lipoproteins are secreted by the heart. (1998) (124)
- ATP-Citrate Lyase Deficiency in the Mouse* (2004) (123)
- HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells (2007) (123)
- Compensatory Increase in Hepatic Lipogenesis in Mice with Conditional Intestine-specific Mttp Deficiency* (2006) (122)
- Overexpression of Hepatic Lipase in Transgenic Mice Decreases Apolipoprotein B-containing and High Density Lipoproteins (1998) (117)
- Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice. (1993) (117)
- GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer. (2007) (117)
- Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia (2010) (116)
- Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100. (2000) (116)
- Increased progerin expression associated with unusual LMNA mutations causes severe progeroid syndromes (2007) (115)
- A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine. (1995) (114)
- Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. (2014) (112)
- Conservation of the Low Density Lipoprotein Receptor‐Binding Domain of Apoprotein B (1986) (111)
- Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling. (2013) (109)
- IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure (2018) (109)
- Chylomicronemia With Low Postheparin Lipoprotein Lipase Levels in the Setting of GPIHBP1 Defects (2010) (108)
- Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100. (1997) (108)
- SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion (2013) (107)
- Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. (2012) (106)
- Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER Published, JLR Papers in Press, February 16, 2003. DOI 10.1194/jlr.M300020-JLR200 (2003) (106)
- The arrestin domain-containing 3 protein regulates body mass and energy expenditure. (2011) (105)
- Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria (2013) (104)
- Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer (2010) (102)
- Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig. (1985) (101)
- Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway* (2005) (101)
- Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia (2017) (100)
- GPIHBP1, an endothelial cell transporter for lipoprotein lipase (2011) (97)
- Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B. (1986) (96)
- Biochemical Studies of Zmpste24-deficient Mice* (2001) (95)
- Characterization of an abnormal species of apolipoprotein B, apolipoprotein B-37, associated with familial hypobetalipoproteinemia. (1987) (94)
- Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation. (2008) (93)
- Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease. (2008) (91)
- An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair. (2011) (91)
- Heart-type Fatty Acid-binding Protein Is Essential for Efficient Brown Adipose Tissue Fatty Acid Oxidation and Cold Tolerance* (2010) (89)
- An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. (2010) (89)
- The C-terminal Polylysine Region and Methylation of K-Ras Are Critical for the Interaction between K-Ras and Microtubules* (2000) (88)
- Cell Nuclei Spin in the Absence of Lamin B1* (2007) (88)
- Lipoprotein Secretion and Triglyceride Stores in the Heart* (2001) (88)
- Early Embryonic Lethality Caused by Disruption of the Gene for Choline Kinase α, the First Enzyme in Phosphatidylcholine Biosynthesis* (2007) (88)
- Macrophage-Targeted Overexpression of Urokinase Causes Accelerated Atherosclerosis, Coronary Artery Occlusions, and Premature Death (2004) (87)
- N-Myristoyltransferase 1 Is Essential in Early Mouse Development* (2005) (86)
- Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes (2016) (85)
- Low plasma cholesterol levels caused by a short deletion in the apolipoprotein B gene. (1988) (85)
- A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation (2003) (84)
- Targeted Disruption of the Idol Gene Alters Cellular Regulation of the Low-Density Lipoprotein Receptor by Sterols and Liver X Receptor Agonists (2011) (83)
- Limited Accumulation of Damaged Proteins inl-Isoaspartyl (d-Aspartyl)O-Methyltransferase-deficient Mice* (2001) (81)
- The Small Molecule Phenamil Induces Osteoblast Differentiation and Mineralization (2009) (81)
- GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons (2007) (80)
- Why are low-density lipoproteins atherogenic? (1994) (79)
- The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain (2016) (79)
- Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration (2013) (78)
- Genetic analysis of a kindred with familial hypobetalipoproteinemia. Evidence for two separate gene defects: one associated with an abnormal apolipoprotein B species, apolipoprotein B-37; and a second associated with low plasma concentrations of apolipoprotein B-100. (1987) (78)
- Abnormal Patterns of Lipoprotein Lipase Release into the Plasma in GPIHBP1-deficient Mice* (2008) (77)
- Apoprotein B-100 production is decreased in subjects heterozygous for truncations of apoprotein B. (1995) (77)
- Defining the Importance of Phosphatidylserine Synthase 2 in Mice* (2002) (77)
- Familial defective apolipoprotein B-100: enhanced binding of monoclonal antibody MB47 to abnormal low density lipoproteins. (1988) (77)
- The Acidic Domain of GPIHBP1 Is Important for the Binding of Lipoprotein Lipase and Chylomicrons* (2008) (76)
- The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding (2016) (76)
- Human Apolipoprotein B Transgenic Mice Generated with 207- and 145-Kilobase Pair Bacterial Artificial Chromosomes (1997) (76)
- IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor (2013) (75)
- Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina (2019) (75)
- Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL. (1995) (75)
- A Deficiency of Microsomal Triglyceride Transfer Protein Reduces Apolipoprotein B Secretion* (2000) (74)
- GPIHBP1 and Plasma Triglyceride Metabolism (2016) (74)
- Familial hypobetalipoproteinemia associated with a mutant species of apolipoprotein B (B-46). (1989) (74)
- Direct Synthesis of Lamin A, Bypassing Prelamin A Processing, Causes Misshapen Nuclei in Fibroblasts but No Detectable Pathology in Mice* (2010) (73)
- Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect (2011) (73)
- The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. (2014) (71)
- Modulation of LMNA splicing as a strategy to treat prelamin A diseases. (2016) (71)
- Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a). (1995) (71)
- Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum (2012) (71)
- Highly Conserved Cysteines within the Ly6 Domain of GPIHBP1 Are Crucial for the Binding of Lipoprotein Lipase* (2009) (70)
- Monoclonal antibody MB19 detects genetic polymorphism in human apolipoprotein B. (1985) (69)
- GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism. (2019) (67)
- d-Aspartate Regulates Melanocortin Formation and Function: Behavioral Alterations in d-Aspartate Oxidase-Deficient Mice (2006) (67)
- Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease. (2007) (67)
- On the Physiological Importance of Endoproteolysis of CAAX Proteins (2004) (66)
- Blocking the Secretion of Hepatic Very Low Density Lipoproteins Renders the Liver More Susceptible to Toxin-induced Injury* (2002) (66)
- Phenotypic Analysis of Seizure-prone Mice Lacking l-Isoaspartate (d-Aspartate)O-Methyltransferase* (1999) (64)
- Parallel expression of the MB19 genetic polymorphism in apoprotein B-100 and apoprotein B-48. Evidence that both apoproteins are products of the same gene. (1986) (64)
- Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation (2007) (64)
- A novel approach to tag and identify geranylgeranylated proteins (2009) (64)
- Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells[S] (2012) (63)
- Assembly of lipoprotein particles containing apolipoprotein-B: structural model for the nascent lipoprotein particle. (2005) (63)
- Transgenic mice expressing both human apolipoprotein B and human CETP have a lipoprotein cholesterol distribution similar to that of normolipidemic humans. (1995) (63)
- New wrinkles in lipoprotein lipase biology (2012) (62)
- Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report (2010) (62)
- Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin. (2011) (61)
- Genetically modified mice for the study of apolipoprotein B. (1998) (61)
- Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor β signaling (2006) (60)
- Transgenic Mice That Overexpress Mouse Apolipoprotein B (1996) (60)
- Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1 (2011) (60)
- Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24 (2016) (60)
- Intensive combination drug therapy of familial hypercholesterolemia with lovastatin, probucol, and colestipol hydrochloride. (1989) (60)
- Structure of the lipoprotein lipase–GPIHBP1 complex that mediates plasma triglyceride hydrolysis (2018) (59)
- Lipoprotein lipase is active as a monomer (2019) (59)
- High-resolution imaging and quantification of plasma membrane cholesterol by NanoSIMS (2017) (58)
- GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding (2015) (57)
- 7 Postisoprenylation protein processing: CXXX (CaaX) endoproteases and isoprenylcysteine carboxyl methyltransferase (2001) (56)
- The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. (2008) (56)
- Assessing the Role of the Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) Three-finger Domain in Binding Lipoprotein Lipase* (2011) (55)
- A Potent HIV Protease Inhibitor, Darunavir, Does Not Inhibit ZMPSTE24 or Lead to an Accumulation of Farnesyl-prelamin A in Cells* (2008) (55)
- Reading-frame restoration with an apolipoprotein B gene frameshift mutation. (1992) (54)
- Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome (2018) (54)
- Targeting Protein Prenylation in Progeria (2013) (53)
- Investigating the purpose of prelamin A processing. (2011) (51)
- High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins. (2005) (50)
- HIV-protease inhibitors block the enzymatic activity of purified Ste24p. (2008) (50)
- Activating the synthesis of progerin, the mutant prelamin A in Hutchinson–Gilford progeria syndrome, with antisense oligonucleotides (2009) (49)
- Apolipoprotein B gene mutations affecting cholesterol levels (1992) (48)
- Understanding the Roles of Nuclear A- and B-type Lamins in Brain Development* (2012) (48)
- Multimerization of Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1 Ly6 Domain* (2014) (48)
- Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene. (1998) (47)
- A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet (1998) (47)
- Intravenous Injection of Apolipoprotein A-V Reconstituted High-Density Lipoprotein Decreases Hypertriglyceridemia in apoav−/− Mice and Requires Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein–Binding Protein 1 (2010) (47)
- Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells (2020) (46)
- Binding Preferences for GPIHBP1, a Glycosylphosphatidylinositol-Anchored Protein of Capillary Endothelial Cells (2010) (46)
- Metabolic adaptations to dietary fat malabsorption in chylomicron-deficient mice. (1999) (46)
- Deletion of the Basement Membrane Heparan Sulfate Proteoglycan Type XVIII Collagen Causes Hypertriglyceridemia in Mice and Humans (2010) (46)
- Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression. (2004) (45)
- Are B-type lamins essential in all mammalian cells? (2011) (45)
- Compromised Mitochondrial Fatty Acid Synthesis in Transgenic Mice Results in Defective Protein Lipoylation and Energy Disequilibrium (2012) (45)
- Expression of human apolipoprotein B90 in transgenic mice. Demonstration that apolipoprotein B90 lacks the structural requirements to form lipoprotein. (1994) (45)
- Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism (2020) (44)
- Nuclear Lamins and Neurobiology (2014) (44)
- Reading-frame Restoration by Transcriptional Slippage at Long Stretches of Adenine Residues in Mammalian Cells* (1997) (44)
- A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase (2018) (44)
- Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution. (2007) (43)
- Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues (2012) (43)
- Transgenic Mice Expressing Human ApoB95 and ApoB97 (1997) (43)
- Targeting GGTase-I Activates RHOA, Increases Macrophage Reverse Cholesterol Transport, and Reduces Atherosclerosis in Mice (2013) (43)
- Lipin-1 and lipin-3 together determine adiposity in vivo. (2014) (43)
- A truncated species of apolipoprotein B (B67) in a kindred with familial hypobetalipoproteinemia. (1991) (43)
- Fibroblasts lacking nuclear lamins do not have nuclear blebs or protrusions but nevertheless have frequent nuclear membrane ruptures (2018) (43)
- Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria (2010) (42)
- Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer element is located between 54 and 62 kilobases 5' to the structural gene. (1998) (42)
- Relative contributions of apolipoprotein(a) and apolipoprotein-B to the development of fatty lesions in the proximal aorta of mice. (1995) (42)
- NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes. (2018) (42)
- An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death (2019) (42)
- Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques. (2014) (42)
- Glycosylphosphatidylinositol‐anchored high‐density lipoprotein‐binding protein 1 and the intravascular processing of triglyceride‐rich lipoproteins (2012) (41)
- Transgene Insertion on Mouse Chromosome 6 Impairs Function of the Uterine Cervix and Causes Failure of Parturition1 (2005) (41)
- Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. (2010) (40)
- Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice. (2006) (39)
- GPIHBP1 and lipolysis: an update (2009) (39)
- Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA. (1993) (38)
- Protein farnesyltransferase inhibitors and progeria. (2006) (38)
- An ApaLI restriction site polymorphism is associated with the MB19 polymorphism in apolipoprotein B. (1989) (37)
- Unexpected Expression Pattern for Glycosylphosphatidylinositol-anchored HDL-binding Protein 1 (GPIHBP1) in Mouse Tissues Revealed by Positron Emission Tomography Scanning* (2010) (37)
- Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL[S] (2017) (36)
- Colestipol-induced changes in LDL composition and metabolism. II. Studies in humans. (1989) (36)
- Identification and molecular analysis of two apoB gene mutations causing low plasma cholesterol levels. (1995) (36)
- Eliminating the Synthesis of Mature Lamin A Reduces Disease Phenotypes in Mice Carrying a Hutchinson-Gilford Progeria Syndrome Allele* (2008) (35)
- LINCing lamin B2 to neuronal migration (2010) (35)
- Behavioural alterations in male mice lacking the gene for d-aspartate oxidase (2006) (35)
- Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice (2014) (34)
- SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression[S] (2016) (33)
- Monoclonal antibody detects Ag polymorphism of apolipoprotein B (1986) (33)
- Nuclear Envelope Protein Lem2 is Required for Mouse Development and Regulates MAP and AKT Kinases (2015) (33)
- A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia. (1992) (33)
- Apolipoprotein B allotypes MB19(1) and MB19(2) in subjects with coronary artery disease and hypercholesterolemia. (1987) (33)
- Macrophages release plasma membrane-derived particles rich in accessible cholesterol (2018) (31)
- Lipoprotein B37, a naturally occurring lipoprotein containing the amino-terminal portion of apolipoprotein B100, does not bind to the apolipoprotein B,E (low density lipoprotein) receptor. (1987) (31)
- Human CYP7A1 deficiency: progress and enigmas. (2002) (31)
- Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-Deficient Mice (2012) (31)
- Nuclear Lamins in the Brain — New Insights into Function and Regulation (2013) (30)
- Insights into apolipoprotein B biology from transgenic and gene-targeted mice. (1999) (30)
- Structural relationship of human apolipoprotein B48 to apolipoprotein B100. (1987) (30)
- Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models. (2008) (30)
- An analysis of the interaction between mouse apolipoprotein B100 and apolipoprotein(a). (2000) (30)
- Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells (2006) (29)
- Sterol Regulatory Element Binding Protein 1a Regulates Hepatic Fatty Acid Partitioning by Activating Acetyl Coenzyme A Carboxylase 2 (2009) (29)
- Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development (2016) (28)
- High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis[S] (2014) (27)
- Inactivation of the Integrin [36 Subunit Gene Reveals a Role of Epithelial Integrins in Regulating Inflammation in the Lungs and Skin (2002) (26)
- Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries[S] (2016) (26)
- Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis (2018) (26)
- RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs (2017) (25)
- Identification and Characterization of a 315-Base Pair Enhancer, Located More than 55 Kilobases 5′ of the Apolipoprotein B Gene, That Confers Expression in the Intestine* (2000) (25)
- GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia. (2017) (25)
- Absence of VLDL secretion does not affect α-tocopherol content in peripheral tissues Published, JLR Papers in Press, May 18, 2006. (2006) (25)
- Four new mutations in the apolipoprotein B gene causing hypobetalipoproteinemia, including two different frameshift mutations that yield truncated apolipoprotein B proteins of identical length. (1993) (24)
- Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content. (1990) (24)
- Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1. (2012) (24)
- Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice. (1999) (24)
- Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane (2020) (24)
- Amino terminus of apolipoprotein B suffices to produce recognition of malondialdehyde-modified low density lipoprotein by the scavenger receptor of human monocyte-macrophages. (1997) (23)
- Carboxyl‐terminal truncation of apolipoproteinB‐100 inhibits lipoprotein(a) particle formation (1994) (23)
- Caution! Analyze transcripts from conditional knockout alleles (2009) (23)
- NanoSIMS imaging: an approach for visualizing and quantifying lipids in cells and tissues (2016) (23)
- Evolution and Medical Significance of LU Domain−Containing Proteins (2019) (23)
- Lowering plasma cholesterol by raising LDL receptors--revisited. (2012) (23)
- Hematologic effects of inactivating the Ras processing enzyme Rce1. (2003) (22)
- A Gene-targeted Mouse Model for Familial Hypobetalipoproteinemia (1998) (22)
- Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2 (2014) (22)
- Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function. (2006) (21)
- An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nuclear Chromatin (2014) (21)
- Prenylcysteine Lyase Deficiency in Mice Results in the Accumulation of Farnesylcysteine and Geranylgeranylcysteine in Brain and Liver* (2002) (21)
- Asymptomatic homozygous hypobetalipoproteinemia associated with apolipoprotein B45.2. (1994) (21)
- The DNA sequences required for apolipoprotein B expression in the heart are distinct from those required for expression in the intestine. (1999) (20)
- Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation (2017) (20)
- Endoproteolytic Processing of RhoA by Rce1 Is Required for the Cleavage of RhoA by Yersinia enterocolitica Outer Protein T (2006) (20)
- Lipoproteins in pinnipeds: analysis of a high molecular weight form of apolipoprotein E. (1991) (20)
- The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding (2021) (19)
- JCL Roundtable: Hypertriglyceridemia due to defects in lipoprotein lipase function. (2015) (19)
- Transgenic mice expressing human apoB100 and apoB48. (1994) (19)
- Isolation of allele-specific, receptor-binding-defective low density lipoproteins from familial defective apolipoprotein B-100 subjects. (1994) (18)
- Relationship of apolipoprotein E phenotypes to hypocholesterolemia. (1993) (18)
- Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia (2019) (18)
- An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum. (2017) (18)
- Construction of two near-kilobase resolution restriction maps of the 5' regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM). (1997) (18)
- Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL[S] (2016) (18)
- Lipoproteins containing apolipoprotein B-100 are secreted by the heart. (1999) (18)
- Detection of two apolipoprotein B species (apoBc and apoBg) by a monoclonal antibody. (1987) (18)
- Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness (2018) (18)
- Expression of P1 DNA in mammalian cells and transgenic mice. (1994) (18)
- Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24 (2012) (17)
- A mouse monoclonal antibody specific for mouse apoB48 and apoB100 produced by immunizing "apoB39-only" mice with mouse apoB48. (2006) (17)
- Cholesterol Intake Modulates Plasma Triglyceride Levels in Glycosylphosphatidylinositol HDL-Binding Protein 1-Deficient Mice (2010) (16)
- Definition of a nonlinear conformational epitope for the apolipoprotein B-100-specific monoclonal antibody, MB47. (1994) (16)
- Biventricular adaptation to volume overload in mice with aortic regurgitation (2009) (16)
- Using genetically engineered mice to understand apolipoprotein-B deficiency syndromes in humans. (1998) (16)
- Generation of transgenic mice from yeast artificial chromosome DNA that has been modified by gene targeting. (1996) (15)
- New Lmna knock-in mice provide a molecular mechanism for the 'segmental aging' in Hutchinson-Gilford progeria syndrome. (2014) (15)
- Genetic analyses of the role of RCE1 in RAS membrane association and transformation. (2008) (14)
- Carboxyl-terminal truncation of apolipoproteinB-100 inhibits lipoprotein(a) particle formation. (1994) (14)
- DYT1 Dystonia Patient-Derived Fibroblasts Have Increased Deformability and Susceptibility to Damage by Mechanical Forces (2018) (14)
- Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins (2020) (14)
- Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding[S] (2017) (14)
- Palmoplantar keratoderma in Slurp2-deficient mice (2015) (14)
- Absence of VLDL secretion does not affect alpha-tocopherol content in peripheral tissues. (2006) (13)
- Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter. (2014) (13)
- Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency (2012) (13)
- Circumventing Embryonic Lethality with Lcmt1 Deficiency: Generation of Hypomorphic Lcmt1 Mice with Reduced Protein Phosphatase 2A Methyltransferase Expression and Defects in Insulin Signaling (2013) (13)
- Modeling Insertional Mutagenesis Using Gene Length and Expression in Murine Embryonic Stem Cells (2007) (13)
- Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases[S] (2012) (13)
- Chylomicronemia from GPIHBP1 autoantibodies (2020) (13)
- GPIHBP1 autoantibody syndrome during interferon β1a treatment. (2019) (13)
- Long runs of adenines and human mutations. (1998) (13)
- Modification of the apolipoprotein B gene in HepG2 cells by gene targeting. (1992) (13)
- GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity (2021) (13)
- Nuclear membrane ruptures underlie the vascular pathology in a mouse model of Hutchinson-Gilford progeria syndrome (2021) (13)
- High-resolution visualization and quantification of nucleic acid–based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS) (2020) (12)
- Intermittent chylomicronemia caused by intermittent GPIHBP1 autoantibodies. (2020) (12)
- Peroxidasin-mediated bromine enrichment of basement membranes (2020) (12)
- Slc25a17 Gene Trapped Mice: PMP34 Plays a Role in the Peroxisomal Degradation of Phytanic and Pristanic Acid (2020) (11)
- Mice that express farnesylated versions of prelamin A in neurons develop achalasia. (2015) (11)
- ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL’s hydrolase domain (2020) (11)
- Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor‐related protein 1 (SLURP1) in Mal de Meleda (2015) (10)
- Extra Rabs unsnarl a lipid traffic jam (2002) (10)
- Do lamin B1 and lamin B2 have redundant functions? (2014) (10)
- 10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins. (2006) (9)
- Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure[S] (2018) (9)
- Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function (2016) (9)
- Thematic Review Series: Lipid Posttranslational Modifications. Prelamin A, Zmpste24, misshapen cell nuclei, and progeria—new evidence suggesting that protein farnesylation could be important for disease pathogenesis Published, JLR Papers in Press, October 5, 2005. DOI 10.1194/jlr.R500011-JLR200 (2005) (9)
- An ELISA for quantifying GPIHBP1 autoantibodies and making a diagnosis of the GPIHBP1 autoantibody syndrome. (2018) (9)
- Immunochemical evidence that human apoB differs when expressed in rodent versus human cells Published, JLR Papers in Press, December 16, 2002. DOI 10.1194/jlr.M200413-JLR200 (2003) (9)
- Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT 3-activated microRNAs (2019) (9)
- Using genetically modified mice to study apolipoprotein B. (1996) (9)
- NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes. (2018) (9)
- Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report (2020) (9)
- Posttranslational Processing of Nuclear Lamins (2011) (8)
- LMNA missense mutations causing familial partial lipodystrophy do not lead to an accumulation of prelamin A (2016) (8)
- The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase (2020) (8)
- An LPL–specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1[S] (2016) (8)
- Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. Commentary (2002) (7)
- Nuclear membrane ruptures, cell death, and tissue damage in the setting of nuclear lamin deficiencies (2020) (7)
- Monoclonal antibody MB 19 detects genetic polymorphism in human apolipoprotein (7)
- AGPAT 6 Is a Novel Microsomal Glycerol-3-Phosphate Acyltransferase ( GPAT ) * (2008) (7)
- Lipoprotein lipase reaches the capillary lumen in chickens despite an apparent absence of GPIHBP1. (2017) (7)
- ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding (2021) (7)
- GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients (2019) (7)
- An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner[S] (2018) (7)
- SREBP-2-defi cient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1 c expression (2016) (7)
- A new monoclonal antibody, 4-1a, that binds to the amino terminus of human lipoprotein lipase. (2014) (7)
- GPIHBP1, a partner protein for lipoprotein lipase, is expressed only in capillary endothelial cells (2020) (7)
- New Lmna knockin mice provide a molecular mechanism for the ‘ segmental aging ’ in Hutchinson – Gilford progeria syndrome { (2014) (6)
- Transgenic Mice Expressing Human ApoB95 and ApoB97 EVIDENCE THAT SEQUENCES WITHIN THE CARBOXYL-TERMINAL PORTION OF HUMAN apoB100 ARE IMPORTANT FOR THE ASSEMBLY OF LIPOPROTEIN(a)* (1997) (6)
- Investigating the purpose of prelamin A processing (2011) (6)
- Identification and characterization of truncated forms of apolipoprotein B in hypobetalipoproteinemia. (1996) (6)
- Binding Preferences for GPIHBP 1 , a Glycosylphosphatidylinositol-Anchored Protein of Capillary Endothelial Cells (2010) (5)
- Autoantibodies against GPIHBP 1 as a Cause of Hypertriglyceridemia (2017) (5)
- Familial defective apolipoprotein B100 : Enhanced binding of monoclonal antibody MB 47 to abnormal low density lipoproteins ( hypercholesterolemia / genetic disease / atherosclerosis / apolipoprotein B100 polymorphism ) (4)
- Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells (2022) (4)
- High-level lipoprotein [a] expression in transgenic mice: Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400467-JLR200evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins (2005) (4)
- A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^LL cleavage occurs first and there is no CaaX processing by ZMPSTE24 (2020) (4)
- A new approach for studying gene regulation by distant DNA elements in transgenic mice. (1999) (4)
- Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis (2023) (3)
- Deficiency in ZMPSTE24 and resulting farnesyl–prelamin A accumulation only modestly affect mouse adipose tissue stores[S] (2020) (3)
- Secretion from cell culture of HDL and VLDL bearing apoB-33 with a large internal deletion. (1997) (3)
- Abstract: 141 TWO MUTATIONS IN GPIHBP1 CAUSE SEVERE CHYLOMICRONEMIA AND PROVIDE EVIDENCE FOR A CRITICAL ROLE OF GPIHBP1 IN HUMAN TRIGLYCERIDE METABOLISM (2009) (2)
- Title Lpcat 3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion (2015) (2)
- Human CYP 7 A 1 deficiency : progress and enigmas (2018) (2)
- Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice. (2018) (2)
- Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin–deficient neurons and fibroblasts (2021) (2)
- Apolipoprotein B Gene Expression in a Series of Human Apolipoprotein B Transgenic Mice Generated withrecA-assisted Restriction Endonuclease Cleavage-modified Bacterial Artificial Chromosomes (1998) (2)
- Mammalian farnesylated protein-converting enzyme 1 (2004) (2)
- A thematic review series: lipid modifications of proteins Published, JLR Papers in Press, September 21, 2005. DOI 10.1194/jlr.E500006-JLR200 (2005) (2)
- Sterol Regulatory Element Binding Protein 1a Regulates Hepatic Fatty Acid Partitioning by Activating Acetyl Coenzyme A Carboxylase 2 (2009) (2)
- A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism (2022) (1)
- The fatty acids from LPL-mediated processing of triglyceride-rich lipoproteins are taken up rapidly by cardiomyocytes (2020) (1)
- Mesenchymal Stem Cells Ameliorate Murine Progeria Phenotype (2008) (1)
- GPIHBP1: a new chylomicronemia gene (2008) (1)
- A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency (2017) (1)
- Author response: SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion (2013) (1)
- P336 ABNORMAL LPL RELEASE LEADS TO CHYLOMICRONEMIA IN THE PRESENCE OF GPIHBP1 DEFECTS (2010) (1)
- Transgenic mice sing both human apolipoprotein 6 and human CETP have a lipoprotein ch erd dist n similar to that of normolipidemic humans (1995) (1)
- NanoSIMS imaging of lipid absorption by intestinal enterocytes (2022) (1)
- The fatty acids from LPL-mediated processing of triglyceride-rich lipoproteins are taken up rapidly by cardiomyocytes. (2020) (1)
- Symposium : Assembly and Physiology of Apolipoprotein B – Containing Lipoproteins : Not Just for Heart Disease Anymore ! Insights into Apolipoprotein B Biology from Transgenic and Gene-Targeted Mice 1 , 2 (1999) (1)
- New Developments in the Lipolytic Processing of Triglyceride‐Rich Lipoproteins (2010) (0)
- Correlative Electron Microscopy and NanoSIMS Analysis for Lipid Studies (2018) (0)
- Identification and characterization of a 315-bp enhancer, located more than 55 kb 5 ′ of the apolipoprotein B gene, that confers expression in the intestine. (2000) (0)
- Response to Gerlic et al. (2014) (0)
- Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis (2018) (0)
- induced myeloproliferative disease - Inactivating Icmt ameliorates K-RAS (2013) (0)
- Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase. (2023) (0)
- Phytanic and pristanic acid breakdown is impaired in Slc25a17−/− mice lacking the peroxisomal membrane solute transporter PMP34 (2009) (0)
- TwoNewMonoclonal Antibody-Based Enzyme-Linked Assaysof Apolipoprotein B (1986) (0)
- Farnesylation of Pex19p: role in mammalian peroxisome biogenesis (2005) (0)
- commentary PCSK 9 function and physiology 1 (2008) (0)
- Subcellular Partitioning of Arsenic Trioxide Revealed by Label-Free Imaging. (2022) (0)
- VLDL or LDL cholesterol: which is more atherogenic? (2000) (0)
- Geranylgeranylation of retinal proteins is essential for cone photoreceptor function and survival (2015) (0)
- Images in Lipid Research (2020) (0)
- A 315-bp enhancer, located more than 55 KB 5′ of the apolipoprotein B gene, confers intestinal expression in transgenic mice (2000) (0)
- Expression of human apo B100 and apo B48 in transgenic mice (1994) (0)
- Detection Of Circulating Gpihbp1-Gpihbp1 Autoantibody Complex In High Tg Plasma Of Patients With A History Of Acute Pancreatitis (2019) (0)
- The zinc finger and BTB domain containing protein ZBTB20 regulates plasma triglyceride metabolism by repressing lipoprotein lipase gene transcription in hepatocytes (2021) (0)
- Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase (2020) (0)
- Pex19p farnesylation is not essential for peroxisome biogenesis in mammals and yeast (2005) (0)
- Nuclear Lamins in the Brain — New Insights into Function and Regulation (2012) (0)
- Monoclonal antibody b 19 detects distinct epitope polymorphism in human apo b (1985) (0)
- PCSK9 function and physiology 1 (2008) (0)
- Correlative Live-Cell, Electron Microscopy and Nanoscale Secondary Ion Mass Spectrometry Elucidates the Mechanism for the Release of Cholesterol-Rich Particles from the Plasma Membrane of Macrophages (2019) (0)
- Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures. (2023) (0)
- Quantitatively Imaging Stable Isotopes at Subcellular Level with Correlative Electron Microscopy and Nanosims Analysis (2014) (0)
- Methyl Esterification of Proteins is Essential for Effective Rod-mediated Vision (2012) (0)
- Chapter 142 – Mammalian Farnesylated Protein-Converting Enzyme 1 (2013) (0)
- The association of paf acetylhydrolase with ldl involves n-terminal domains in the enzyme and c-terminal domains in apolipoprotein B (1996) (0)
- University of Southern Denmark The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain Mysling, (2016) (0)
- Genetic analyses of Rce1 function in Ras membrane association and function (2008) (0)
- Syddansk Universitet The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain Mysling, (2016) (0)
- Abstract 20013: The Alpha-Arrestin Arrdc3 Regulates Obesity in Mice and Humans (2010) (0)
- An ELISA for measuring GPIHBP1 levels in human plasma or serum (2018) (0)
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What Schools Are Affiliated With Stephen G. Young?
Stephen G. Young is affiliated with the following schools:
- University of Western Australia
- Ghent University
- Washington University in St. Louis
- Tufts University
- University of California, San Diego
- University of California, Los Angeles
- Princeton University
- Stanford University
- University of Iowa
- University of Washington
- Texas A&M University
- University of California, San Francisco