Stephen H. Bryant
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Stephen H. Bryant's AcademicInfluence.com Rankings
Stephen H. Bryantbiology Degrees
Biology
#12230
World Rank
#15693
Historical Rank
Bioinformatics
#148
World Rank
#150
Historical Rank
Biotechnology
#215
World Rank
#217
Historical Rank
Computational Biology
#268
World Rank
#269
Historical Rank
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Biology
Stephen H. Bryant's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Stephen H. Bryant Influential?
(Suggest an Edit or Addition)Stephen H. Bryant's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Database resources of the National Center for Biotechnology Information (2017) (4332)
- PubChem Substance and Compound databases (2015) (3124)
- CDD: a Conserved Domain Database for the functional annotation of proteins (2010) (2948)
- CDD: NCBI's conserved domain database (2014) (2797)
- CDD/SPARCLE: functional classification of proteins via subfamily domain architectures (2016) (1990)
- CD-Search: protein domain annotations on the fly (2004) (1850)
- Open mass spectrometry search algorithm. (2004) (1430)
- CDD: a Conserved Domain Database for protein classification (2004) (1196)
- CDD: specific functional annotation with the Conserved Domain Database (2008) (1138)
- PubChem: a public information system for analyzing bioactivities of small molecules (2009) (1134)
- PubChem: Integrated Platform of Small Molecules and Biological Activities (2008) (1131)
- Surprising similarities in structure comparison. (1996) (1081)
- CDD: a conserved domain database for interactive domain family analysis (2006) (869)
- CDD: conserved domains and protein three-dimensional structure (2012) (844)
- CDD: a curated Entrez database of conserved domain alignments (2003) (788)
- The NCBI BioSystems database (2009) (758)
- CDD: a database of conserved domain alignments with links to domain three-dimensional structure (2002) (661)
- CDART: protein homology by domain architecture. (2002) (656)
- PubChem's BioAssay Database (2011) (493)
- Threading a database of protein cores (1995) (489)
- Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review (2012) (460)
- An empirical energy function for threading protein sequence through the folding motif (1993) (396)
- Database resources of the National Center for Biotechnology Information (2020) (323)
- PubChem as a public resource for drug discovery. (2010) (297)
- Database resources of the National Center for Biotechnology Information (2018) (296)
- Threading analysis suggests that the obese gene product may be a helical cytokine (1995) (282)
- An overview of the PubChem BioAssay resource (2009) (281)
- Cn3D: sequence and structure views for Entrez. (2000) (278)
- Critical assessment of methods of protein structure prediction (CASP): Round II (1997) (276)
- MMDB and VAST+: tracking structural similarities between macromolecular complexes (2013) (252)
- PubChem BioAssay: 2014 update (2013) (243)
- Domain size distributions can predict domain boundaries (2000) (188)
- MMDB: Entrez's 3D-structure database (2002) (173)
- Extent and nature of contacts between protein molecules in crystal lattices and between subunits of protein oligomers (1997) (162)
- Statistics of sequence-structure threading. (1995) (161)
- Eukaryotic translation elongation factor 1γ contains a glutathione transferase domain—Study of a diverse, ancient protein super family using motif search and structural modeling (1994) (153)
- MMDB: Entrez's 3D structure database (1999) (146)
- Prediction of functional sites by analysis of sequence and structure conservation (2004) (136)
- Database resources of the National Center for Biotechnology Information (2007) (133)
- Database resources of the National Center for Biotechnology Information (2008) (131)
- Combination of threading potentials and sequence profiles improves fold recognition. (2000) (126)
- PubChem3D: a new resource for scientists (2011) (121)
- Modeling the evolution of protein domain architectures using maximum parsimony. (2007) (118)
- MMDB: annotating protein sequences with Entrez's 3D-structure database (2006) (111)
- MMDB: 3D structures and macromolecular interactions (2011) (109)
- Caught in self-interaction: evolutionary and functional mechanisms of protein homooligomerization (2011) (103)
- Database resources of the National Center for Biotechnology Information (2012) (100)
- Database resources of the National Center for Biotechnology Information (2011) (90)
- Developing and validating predictive decision tree models from mining chemical structural fingerprints and high–throughput screening data in PubChem (2008) (90)
- IBIS (Inferred Biomolecular Interaction Server) reports, predicts and integrates multiple types of conserved interactions for proteins (2011) (87)
- Inferred Biomolecular Interaction Server—a web server to analyze and predict protein interacting partners and binding sites (2009) (87)
- Finding biologically relevant protein domain interactions: Conserved binding mode analysis (2006) (81)
- Predicting drug-target interactions by dual-network integrated logistic matrix factorization (2017) (78)
- The PubChem chemical structure sketcher (2009) (76)
- Database resources of the National Center for Biotechnology Information (2014) (76)
- iCn3D, a web-based 3D viewer for sharing 1D/2D/3D representations of biomolecular structures (2018) (76)
- Evaluation of threading specificity and accuracy (1996) (75)
- PUG-SOAP and PUG-REST: web services for programmatic access to chemical information in PubChem (2015) (75)
- Predicting drug–drug interactions through drug structural similarities and interaction networks incorporating pharmacokinetics and pharmacodynamics knowledge (2017) (71)
- Database resources of the National Center for Biotechnology Information (2009) (68)
- A novel method for mining highly imbalanced high-throughput screening data in PubChem (2009) (66)
- Evolution of protein binding modes in homooligomers. (2010) (66)
- A dynamic look at structures: WWW-Entrez and the Molecular Modeling Database. (1996) (64)
- Threading with explicit models for evolutionary conservation of structure and sequence (1999) (62)
- Identification of homologous core structures (1999) (62)
- Modulating protein-protein interactions with small molecules: the importance of binding hotspots. (2012) (61)
- Identifying Compound-Target Associations by Combining Bioactivity Profile Similarity Search and Public Databases Mining (2011) (60)
- Outcome of a workshop on archiving structural models of biological macromolecules. (2006) (59)
- Molecular Imaging and Contrast Agent Database (MICAD): Evolution and Progress (2012) (59)
- Functional specificity lies within the properties and evolutionary changes of amino acids. (2007) (59)
- An efficient algorithm coupled with synthetic minority over-sampling technique to classify imbalanced PubChem BioAssay data. (2014) (59)
- Database resources of the National Center for Biotechnology Information (2005) (58)
- PubChem3D: conformer ensemble accuracy (2013) (55)
- New Programs for Protein Tertiary Structure Prediction (1993) (54)
- Improved prediction of drug-target interactions using regularized least squares integrating with kernel fusion technique. (2016) (48)
- Literature information in PubChem: associations between PubChem records and scientific articles (2016) (48)
- MMDB: 3D structure data in Entrez (2000) (47)
- Binary Classification of Aqueous Solubility Using Support Vector Machines with Reduction and Recombination Feature Selection (2011) (44)
- PubChem applications in drug discovery: a bibliometric analysis. (2014) (43)
- A measure of success in fold recognition. (1997) (40)
- Refining multiple sequence alignments with conserved core regions (2006) (40)
- Pathway Analysis for Drug Repositioning Based on Public Database Mining (2014) (38)
- PubChem3D: Conformer generation (2011) (38)
- Assessing data quality of peptide mass spectra obtained by quadrupole ion trap mass spectrometry. (2005) (38)
- Comparison of sequence and structure alignments for protein domains (2002) (37)
- Functional states of homooligomers: insights from the evolution of glycosyltransferases. (2010) (37)
- Fast 3D shape screening of large chemical databases through alignment-recycling (2007) (37)
- FSelector: a Ruby gem for feature selection (2012) (37)
- Measures of threading specificity and accuracy (1997) (35)
- A comparison of position‐specific score matrices based on sequence and structure alignments (2002) (35)
- Database resources of the National Center for Biotechnology Information (2021) (33)
- MMDB: An ASN.1 Specification for Macromolecular Structure (1995) (33)
- Large-Scale Prediction of Drug-Target Interaction: a Data-Centric Review (2017) (33)
- Assessment of Conformational Ensemble Sizes Necessary for Specific Resolutions of Coverage of Conformational Space (2007) (30)
- Exploring functional roles of multibinding protein interfaces (2009) (30)
- A retrospective analysis of CASP2 threading predictions (1997) (30)
- A survey of across-target bioactivity results of small molecules in PubChem (2009) (30)
- Database resources of the National Center for Biotechnology Information. (2001) (29)
- PubChem BioAssay: A Decade’s Development toward Open High-Throughput Screening Data Sharing (2017) (27)
- Open-source chemogenomic data-driven algorithms for predicting drug-target interactions (2019) (26)
- Homology model building of the HMG-1 box structural domain. (1995) (26)
- A structure-based method for protein sequence alignment (2005) (26)
- Annotation of functional sites with the Conserved Domain Database (2012) (26)
- Investigating the correlations among the chemical structures, bioactivity profiles and molecular targets of small molecules (2010) (25)
- PubChem3D: Similar conformers (2011) (25)
- Pharmacophore and 3D-QSAR Characterization of 6-Arylquinazolin-4-amines as Cdc2-like Kinase 4 (Clk4) and Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (Dyrk1A) Inhibitors (2013) (24)
- PKB: A program system and data base for analysis of protein structure (1989) (24)
- Computational analysis of the cathepsin B inhibitors activities through LR‐MMPBSA binding affinity calculation based on docked complex (2009) (21)
- PubChem structure–activity relationship (SAR) clusters (2015) (21)
- PubChem3D: Biologically relevant 3-D similarity (2011) (20)
- Effects of multiple conformers per compound upon 3-D similarity search and bioassay data analysis (2012) (20)
- Homology Inference of Protein-Protein Interactions via Conserved Binding Sites (2012) (18)
- A measure of progress in fold recognition? (1999) (18)
- Links from genome proteins to known 3-D structures. (2000) (18)
- Three dimensional structure of the pFc' fragment of guinea pig IgG1. (1979) (16)
- Knowledge-based annotation of small molecule binding sites in proteins (2010) (16)
- Correctly folded proteins make twice as many hydrophobic contacts. (1987) (15)
- The identification of complete domains within protein sequences using accurate E-values for semi-global alignment (2007) (15)
- Database resources of the National Center for Biotechnology Information (2009) (15)
- PubChem3D: Diversity of shape (2011) (15)
- PubChem3D: Shape compatibility filtering using molecular shape quadrupoles (2011) (13)
- Reply: A polymerase I palm in adenylyl cyclase? (1997) (12)
- Preliminary crystallographic X-ray data for an NAD(P)H:quinone reductase from mouse liver. (1986) (12)
- Protein homologous cores and loops: important clues to evolutionary relationships between structurally similar proteins (2007) (12)
- Target enhanced 2D similarity search by using explicit biological activity annotations and profiles (2015) (12)
- Finding Potential Multitarget Ligands Using PubChem. (2018) (12)
- A new chemoinformatics approach with improved strategies for effective predictions of potential drugs (2018) (11)
- Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold (2016) (11)
- Similar compounds versus similar conformers: complementarity between PubChem 2-D and 3-D neighboring sets (2016) (11)
- Topographic analysis of human follicle-stimulating hormone-β using anti-peptide antisera (1992) (10)
- Supporting precision medicine by data mining across multi‐disciplines: an integrative approach for generating comprehensive linkages between single nucleotide variants (SNVs) and drug‐binding sites (2017) (10)
- Improving protein structure similarity searches using domain boundaries based on conserved sequence information (2009) (10)
- High-Throughput Screening Assay Datasets from the PubChem Database (2017) (10)
- State of the art: refinement of multiple sequence alignments (2006) (10)
- State of the art: refinement of multiple sequence alignments (2010) (9)
- QSAR models for predicting cathepsin B inhibition by small molecules—Continuous and binary QSAR models to classify cathepsin B inhibition activities of small molecules (2010) (8)
- Hydrophobic potentials from statistical analysis of protein structures. (1991) (7)
- Cheminformatics analysis of the AR agonist and antagonist datasets in PubChem (2016) (6)
- PubChem atom environments (2015) (6)
- Comparison of protein structural profiles by interactive computer graphics (1987) (6)
- Characterizing protein domain associations by Small-molecule ligand binding. (2012) (6)
- Increasing peptide identifications and decreasing search times for ETD spectra by pre-processing and calculation of parent precursor charge (2012) (6)
- MMDB: Entrez's 3D structure database. (1999) (5)
- Molecular‐replacement structure of guinea pig IgGl pFc' refined at 3.1Å resolution (1985) (5)
- Surprising similarities in structure comparison. Review article (1997) (5)
- Structure databases. (1998) (5)
- Collection and standardization of crystal structure data by the Protein Data Bank (1987) (4)
- Multi-conformation 3D QSAR study of benzenesulfonyl-pyrazol-ester compounds and their analogs as cathepsin B inhibitors. (2011) (4)
- iCn3D, a Web-based 3D Viewer for the Visualization of Biomolecular Structure and Sequence Annotation (2018) (4)
- PubChem 3 D : Conformer generation (2011) (4)
- Mass Spectrometry Search Algorithm (4)
- Automated annotation of chemical names in the literature with tunable accuracy (2011) (4)
- MOLECULAR-REPLACEMENT STRUCTURE OF GUINEA PIG IGG1 P*FC(PRIME) REFINED AT 3.1 ANGSTROMS RESOLUTION (1982) (4)
- Biological Assembly Comparison with VAST. (2020) (3)
- Automatic annotation of experimentally derived, evolutionarily conserved post-translational modifications onto multiple genomes (2011) (3)
- Abstract 95: Phylogenetic classification, structural evolution, and functional divergence of the ABC-type transporters: Inferences derived from CDTree/Cn3D software applications (2010) (3)
- PubChem 3 D : Similar conformers (2011) (3)
- A proposed structural model of domain 1 of fasciclin III neural cell adhesion protein based on an inverse folding algorithm (1995) (3)
- The statistics of unique native states for random peptides (1996) (2)
- Molecular imaging and contrast agent database (MICAD): Progress and current status (2010) (2)
- PubChem Laboratory Chemical Safety Summary (2015) (2)
- The combinatorics and extreme value statistics of protein threading (1999) (1)
- PubChem 3 D : Diversity of shape (2011) (1)
- Increasing peptide identifications and decreasing search times for ETD spectra by pre-processing and calculation of parent precursor charge (2012) (1)
- PubChem: atom environments for molecule standardization (2013) (1)
- Large-Scale Prediction of Drug-Target Interaction: a Data-Centric Review (2017) (0)
- Abstract 1090: Evolutionary, structural, and functional insights into the seven-transmembrane GPCR superfamily through NCBI's Conserved Domain Database (2015) (0)
- Bridging Chemical and Biological Information: Public Knowledge Spaces (2011) (0)
- Figure 1. [PubChem BioAssay FTP directory structure.]. (2014) (0)
- Table 1. [A list of Web-based PubChem services for the BioAssay resource]. (2014) (0)
- Inferring protein-protein interactions based on conservation of interfaces in homologs (2010) (0)
- Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review (2012) (0)
- Myosin superfamily classification using the Conserved Domain Database (CDD) resource at NCBI (2016) (0)
- Conserved Domain Database (CDD): functional annotation of protein families (2016) (0)
- 3. Macromolecular Structure Databases (2003) (0)
- Functional characterization of proteins by domain architecture (2016) (0)
- Abstract 2900: Phylogenetic classification, structural evolution, and functional divergence of the Ras superfamily of GTPases as tracked by the Conserved Domain Database (CDD).. (2013) (0)
- SPARCLE: Functional characterization of proteins by domain architecture (2017) (0)
- Abstract 556: CDD: functional insights into orphan GPCRs via subfamily domain architectures (2017) (0)
- MOESM5 of Cheminformatics analysis of the AR agonist and antagonist datasets in PubChem (2016) (0)
- PubChem: The NIH Public Repository for Small Molecules and Biological Screening Results (2009) (0)
- MOESM2 of Cheminformatics analysis of the AR agonist and antagonist datasets in PubChem (2016) (0)
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