Stephen J. Lippard
#11,909
Most Influential Person Now
American chemist
Stephen J. Lippard's AcademicInfluence.com Rankings
Stephen J. Lippardchemistry Degrees
Chemistry
#111
World Rank
#270
Historical Rank
#52
USA Rank
Inorganic Chemistry
#5
World Rank
#5
Historical Rank
#4
USA Rank
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Chemistry
Stephen J. Lippard's Degrees
- Bachelors Chemistry Haverford College
Why Is Stephen J. Lippard Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephen James Lippard is the Arthur Amos Noyes Emeritus Professor of Chemistry at the Massachusetts Institute of Technology. He is considered one of the founders of bioinorganic chemistry, studying the interactions of nonliving substances such as metals with biological systems. He is also considered a founder of metalloneurochemistry, the study of metal ions and their effects in the brain and nervous system. He has done pioneering work in understanding protein structure and synthesis, the enzymatic functions of methane monooxygenase , and the mechanisms of cisplatin anticancer drugs. His work has applications for the treatment of cancer, for bioremediation of the environment, and for the development of synthetic methanol-based fuels.
Stephen J. Lippard's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cellular processing of platinum anticancer drugs (2005) (3131)
- Structure, Recognition, and Processing of Cisplatin-DNA Adducts. (1999) (2486)
- Tools and tactics for the optical detection of mercuric ion. (2008) (1942)
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs. (2016) (1489)
- Principles Of Bioinorganic Chemistry (1994) (1294)
- Direct cellular responses to platinum-induced DNA damage. (2007) (1204)
- Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles (2008) (893)
- Structural aspects of platinum anticancer drug interactions with DNA (1987) (854)
- New metal complexes as potential therapeutics. (2003) (792)
- Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane (1993) (701)
- Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin (1995) (635)
- Reactions of Non-Heme Iron(II) Centers with Dioxygen in Biology and Chemistry (1994) (632)
- Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. (2008) (598)
- The ophiolite of northern Oman (1986) (591)
- Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution. (2001) (573)
- Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(IV) anticancer drug design. (2007) (559)
- Cisplatin: from DNA damage to cancer chemotherapy. (2001) (537)
- A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. (2003) (532)
- Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. (2009) (529)
- Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy (2010) (520)
- Synthetic models for non-heme carboxylate-bridged diiron metalloproteins: strategies and tactics. (2004) (520)
- Cisplatin and DNA repair in cancer chemotherapy. (1995) (488)
- Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins (1999) (483)
- A New Cell-Permeable Fluorescent Probe for Zn2+ (2000) (477)
- Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo (2011) (472)
- Inhibition of transcription by platinum antitumor compounds. (2009) (463)
- Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. (1992) (458)
- Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins. (2001) (457)
- Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. (2009) (446)
- Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA. (1985) (445)
- Synthetic methods for the preparation of platinum anticancer complexes. (2013) (439)
- Redox activation of metal-based prodrugs as a strategy for drug delivery. (2012) (420)
- Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons (2013) (410)
- Platinum-195 NMR kinetic and mechanistic studies of cis- and trans-diamminedichloroplatinum(II) binding to DNA (1990) (390)
- Organic cation transporters are determinants of oxaliplatin cytotoxicity. (2006) (386)
- Turn-on and ratiometric mercury sensing in water with a red-emitting probe. (2007) (376)
- Mechanistic studies on the hydroxylation of methane by methane monooxygenase. (2003) (367)
- X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]. (1985) (366)
- Dioxygen activation in soluble methane monooxygenase. (2011) (355)
- Oxo‐Bridged Polyiron Centers in Biology and Chemistry (1988) (336)
- Repair of cisplatin--DNA adducts by the mammalian excision nuclease. (1996) (335)
- HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease. (1994) (334)
- Crystal Structure of the Anticancer Drug Cisplatin Bound to Duplex DNA (1996) (316)
- Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug (2015) (313)
- A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress (2017) (311)
- ZP4, an improved neuronal Zn2+ sensor of the Zinpyr family. (2003) (303)
- Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate (2009) (302)
- [Fe(OMe)2(O2CCH2Cl)]10, a Molecular Ferric Wheel (1994) (301)
- Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery (2014) (299)
- Mononuclear and Polynuclear Chemistry of Rhenium (III): Its Pronounced Homophilicity (1964) (296)
- Visualization of nitric oxide in living cells by a copper-based fluorescent probe (2006) (291)
- Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug (2013) (285)
- Chemical Characterization of the Smallest S-Nitrosothiol, HSNO; Cellular Cross-talk of H2S and S-Nitrosothiols (2012) (282)
- New chemistry of an old molecule: cis-[Pt(NH3)2Cl2]. (1982) (278)
- Platinum complexes: probes of polynucleotide structure and antitumor drugs (1978) (276)
- Monodentate carboxylate complexes and the carboxylate shift : implications for polymetalloprotein structure and function (1991) (268)
- Binding of platinum and palladium metallointercalation reagents and antitumor drugs to closed and open DNAs. (1976) (267)
- DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II). (1991) (264)
- Unwinding of supercoiled DNA by platinum-ethidium and related complexes (1992) (261)
- α(V)β(3) integrin-targeted PLGA-PEG nanoparticles for enhanced anti-tumor efficacy of a Pt(IV) prodrug. (2012) (260)
- Magnetostructural correlations in magnetically coupled (.mu.-oxo)diiron(III) complexes (1991) (257)
- Metallointercalation reagents. 2-hydroxyethanethiolato(2,2',2'-terpyridine)-platinum(II) monocation binds strongly to DNA by intercalation. (1974) (256)
- Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile (2012) (252)
- Understanding and improving platinum anticancer drugs--phenanthriplatin. (2014) (250)
- Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. (1995) (247)
- NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin. (1998) (245)
- Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes. (2006) (239)
- Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing (2007) (238)
- Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine? (2003) (234)
- Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex. (2010) (234)
- The coordination chemistry of platinum anticancer drugs and related compounds with DNA (1990) (233)
- Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix. (1979) (229)
- Phosphorescent sensor for robust quantification of copper(II) ion. (2011) (222)
- A novel two-fluorophore approach to ratiometric sensing of Zn(2+). (2003) (222)
- Synthesis, characterization, and cytotoxicity of a series of estrogen-tethered platinum(IV) complexes. (2004) (219)
- Meeting of the minds: Metalloneurochemistry (2003) (219)
- Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. (1992) (218)
- QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). (2005) (215)
- Phosphorescent sensor for biological mobile zinc. (2011) (210)
- Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting. (2009) (210)
- Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes. (2010) (208)
- Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. (2006) (208)
- Kinetic and spectroscopic characterization of intermediates and component interactions in reactions of methane monooxygenase from Methylococcus capsulatus (Bath) (1995) (205)
- CF2H, a Hydrogen Bond Donor. (2017) (204)
- cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects (2008) (202)
- Assembly and characterization of an accurate model for the diiron center in hemerythrin (1984) (201)
- Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature. (2008) (201)
- Metallointercalation reagents. Synthesis, characterization, and structural properties of thiolato(2,2',2''-terpyridine)platinum(II) complexes (1976) (201)
- Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin. (2000) (201)
- Imaging mobile zinc in biology. (2010) (199)
- Binuclear Manganese(III) Complexes of Potential Biological Significance (1987) (197)
- Metal-based turn-on fluorescent probes for sensing nitric oxide. (2007) (196)
- Sequence-dependent termination of in vitro DNA synthesis by cis- and trans-diamminedichloroplatinum (II). (1985) (195)
- Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. (2010) (191)
- A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. (2004) (190)
- Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages (2008) (188)
- High-mobility-group 1 protein mediates DNA bending as determined by ring closures. (1993) (183)
- A Fast and Selective Near-Infrared Fluorescent Sensor for Multicolor Imaging of Biological Nitroxyl (HNO) (2014) (183)
- In vivo effects of cis- and trans-diamminedichloroplatinum(II) on SV40 chromosomes: differential repair, DNA-protein cross-linking, and inhibition of replication. (1985) (181)
- 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex. (2001) (181)
- Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro (2002) (180)
- Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. (2008) (178)
- Crystal and molecular structure of cis-[Pt(NH3)2{d(pGpG)}], the principal adduct formed by cis-diamminedichloroplatinum(II) with DNA (1988) (176)
- Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. (1996) (175)
- Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin. (1993) (172)
- Monofunctional and higher-valent platinum anticancer agents. (2013) (170)
- Vesicular Zinc Promotes Presynaptic and Inhibits Postsynaptic Long-Term Potentiation of Mossy Fiber-CA3 Synapse (2011) (170)
- A highly selective turn-on colorimetric, red fluorescent sensor for detecting mobile zinc in living cells. (2010) (166)
- Mechanistic studies of the reaction of reduced methane monooxygenase hydroxylase with dioxygen and substrates (1999) (163)
- Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins. (2006) (163)
- Structure and Mössbauer Spectrum of a (μ-1,2-Peroxo)bis(μ-carboxylato)diiron(III) Model for the Peroxo Intermediate in the Methane Monooxygenase Hydroxylase Reaction Cycle (1996) (162)
- Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): Implications for substrate gating and component interactions (1997) (161)
- Encapsulation of Pt(iv) prodrugs within a Pt(ii) cage for drug delivery (2014) (159)
- Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors. (2011) (154)
- Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site. (2001) (154)
- Conferences and Meetings (1969) (153)
- Synthesis, characterization, and biological activity of cis-diammineplatinum(II) complexes of the DNA intercalators 9-aminoacridine and chloroquine (1990) (152)
- Targeting mitochondrial DNA with a platinum-based anticancer agent. (2013) (149)
- Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner* (2008) (147)
- Telomere loss in cells treated with cisplatin. (1998) (147)
- Ophiolites and Oceanic Lithosphere (1984) (146)
- Crystal Structure of the Toluene/o-Xylene Monooxygenase Hydroxylase from Pseudomonas stutzeri OX1 (2004) (146)
- Understanding zinc quantification with existing and advanced ditopic fluorescent Zinpyr sensors. (2011) (146)
- p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells. (1998) (145)
- Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. (2006) (145)
- Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance. (2018) (145)
- X-ray absorption, Moessbauer, and EPR studies of the dinuclear iron center in the hydroxylase component of methane monooxygenase (1991) (143)
- New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensor. (2008) (143)
- Synthesis and characterization of (.mu.-hydroxo)bis(.mu.-acetato)diiron(II) and (.mu.-oxo)bis(.mu.-acetato)diiron(III) 1,4,7-trimethyl-1,4,7-triazacyclononane complexes as models for binuclear iron centers in biology; properties of the mixed valence diiron(II,III) species (1987) (142)
- Radical clock substrate probes and kinetic isotope effect studies of the hydroxylation of hydrocarbons by methane monooxygenase (1993) (138)
- Fluorescent probes to investigate nitric oxide and other reactive nitrogen species in biology (truncated form: fluorescent probes of reactive nitrogen species). (2010) (138)
- Synthesis, structure, and properties of an undecairon(III) oxo-hydroxo aggregate: an approach to the polyiron core in ferritin (1987) (130)
- Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer therapy. (2016) (129)
- A Cyclic Octadecairon(III) Complex, the Molecular 18‐Wheeler (1997) (129)
- Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3)2(N3-cytosine)Cl]+. (1990) (128)
- Volcanic rocks beneath the Semail Ophiolite nappe in the northern Oman mountains and their significance in the Mesozoic evolution of Tethys (1980) (127)
- A mixed-valent polyiron oxo complex that models the biomineralization of the ferritin core. (1993) (126)
- The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove. (1988) (126)
- Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells (2013) (126)
- Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn2+ sensors. (2009) (125)
- Spectroscopic detection of intermediates in the reaction of dioxygen with the reduced methane monooxygenase/hydroxylase from Methylococcus capsulatus (Bath) (1994) (125)
- Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. (2004) (124)
- Structural determinations of four mono- and binuclear tertiary phosphine and arsine complexes of copper(I) chloride (1976) (123)
- Reversible protonation of the oxo bridge in a hemerythrin model compound. Synthesis, structure, and properties of (.mu.-hydroxo)bis(.mu.-acetato)bis[hydrotris(1-pyrazolyl)borato]diiron(III) [(HB(pz)3)Fe(OH)(O2CCH3)2Fe(HB(pz)3)2]+ (1984) (122)
- ICCC34 — Golden Edition of Coordination Chemistry Reviews. Coordination Chemistry for the Neurosciences (2001) (122)
- Understanding the dioxygen reaction chemistry of diiron proteins through synthetic modeling studies (2000) (122)
- Inhibition of the BamHI cleavage and unwinding of pBR322 deoxyribonucleic acid by the antitumor drug cis-dichlorodiammineplatinum(II). (1981) (120)
- A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy. (2015) (119)
- Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin. (1990) (117)
- Chemistry and molecular biology of platinum anticancer drugs (1987) (117)
- Interaction of Urea with a Hydroxide-Bridged Dinuclear Nickel Center: An Alternative Model for the Mechanism of Urease (2000) (117)
- Replication inhibition and translesion synthesis on templates containing site-specifically placed cis-diamminedichloroplatinum(II) DNA adducts. (1992) (117)
- Synthesis and crystal structure of cis-diammineplatinum α-pyridone blue (1977) (116)
- Characterization of iron dinitrosyl species formed in the reaction of nitric oxide with a biological Rieske center. (2010) (116)
- The stratigraphy and structure of the Kamasia Range, Kenya Rift Valley (1978) (116)
- A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells. (2016) (116)
- X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct (2010) (115)
- Cisplatin and related anticancer drugs: recent advances and insights. (2004) (115)
- Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. (2004) (112)
- Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases. (2007) (110)
- Control of Substrate Access to the Active Site in Methane Monooxygenase (2013) (110)
- Copper complexes for fluorescence-based NO detection in aqueous solution. (2005) (108)
- X-ray fiber diffraction evidence for neighbor exclusion binding of a platinum metallointercalation reagent to DNA. (1975) (108)
- Synthesis and structure of [Fe(OMe)2(O2CCH2Cl)]10: a molecular ferric wheel (1990) (107)
- Stereochemically Nonrigid Organometallic Compounds. I. π-Cyclopentadienyliron Dicarbonyl σ-Cyclopentadiene1 (1966) (107)
- Solid state structure, magnetic susceptibility, and single crystal ESR properties of cis-diammineplatinum .alpha.-pyridone blue (1979) (106)
- An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts. (1992) (105)
- Binding of platinum(II) intercalation reagents to deoxyribnonucleic acid. Dependence on base-pair composition, nature of the intercalator, and ionic strength. (1979) (105)
- Visualization of nitric oxide production in the mouse main olfactory bulb by a cell-trappable copper(II) fluorescent probe (2010) (104)
- Copper(II) chemistry in hexaaza binucleating macrocycles: hydroxide and acetate derivatives (1984) (104)
- Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450 (2003) (104)
- Structural characterization by EXAFS spectroscopy of the binuclear iron center in protein A of methane monooxygenase from Methylococcus capsulatus (Bath) (1988) (104)
- The rhodafluor family. An initial study of potential ratiometric fluorescent sensors for Zn2+. (2002) (104)
- Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. (2004) (103)
- Modeling Carboxylate-Bridged Dinuclear Active Sites in Metalloenzymes Using a Novel Naphthyridine-Based Dinucleating Ligand (2000) (103)
- Membrane-permeable and -impermeable sensors of the Zinpyr family and their application to imaging of hippocampal zinc in vivo. (2004) (102)
- Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II) (1989) (102)
- Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols. (2008) (102)
- Dioxygen activation in methane monooxygenase: a theoretical study. (2004) (102)
- Sequence dependent binding of cis-dichlorodiammineplatinum(II) to DNA (1980) (102)
- (.mu.-Oxo)bis(.mu.-acetato)bis(tri-1-pyrazolylborato)diiron(III), [(HBpz3)FeO(CH3CO2)2Fe(HBpz3)]: model for the binuclear iron center of hemerythrin (1983) (101)
- Soluble methane monooxygenase: activation of dioxygen and methane. (2002) (101)
- DNA adducts of cis-diamminedichloroplatinum(II) and its trans isomer inhibit RNA polymerase II differentially in vivo. (1995) (101)
- Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro. (1982) (100)
- ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. (2004) (99)
- Electron spin resonance, magnetic, and x-ray crystallographic studies of a binuclear, imidazolate bridged copper(II) complex, [(TMDT)2Cu2(im)(ClO4)2](ClO4) (1978) (99)
- Alkyl Transfer to Metal Thiolates: Kinetics, Active Species Identification, and Relevance to the DNA Methyl Phosphotriester Repair Center of Escherichia coli Ada. (1997) (99)
- Synthesis and characterization of trinuclear iron(II) and manganese(II) carboxylate complexes : structural trends in low valent iron and manganese carboxylates (1992) (98)
- A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. (2010) (98)
- Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77 A resolution. (2010) (96)
- The 15 years of reductive coupling: what have we learned? (1993) (96)
- Isotopic and trace element evidence from lavas, bearing on mantle heterogeneity beneath Kenya (1980) (95)
- Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration (2017) (95)
- Chemical Approach to Positional Isomers of Glucose-Platinum Conjugates Reveals Specific Cancer Targeting through Glucose-Transporter-Mediated Uptake in Vitro and in Vivo. (2016) (95)
- Selective labeling of extracellular proteins containing polyhistidine sequences by a fluorescein-nitrilotriacetic acid conjugate. (2006) (95)
- Characterization of a Diiron(III) Peroxide Intermediate in the Reaction Cycle of Methane Monooxygenase Hydroxylase from Methylococcus capsulatus (Bath) (1995) (95)
- A Cyclic Hexairon(III) Complex with an Octahedrally Coordinated Sodium Ion at the Center, an Example of the [12]Metallacrown‐6 Structure Type (1995) (94)
- Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): evidence for a multi-step, proton-dependent reaction pathway. (2009) (94)
- Magnetic exchange in imidazolate-bridged copper(II) complexes (1982) (94)
- Nucleotide excision repair from site-specifically platinum-modified nucleosomes. (2003) (94)
- In vitro anticancer activity of cis-diammineplatinum(II) complexes with β-diketonate leaving group ligands. (2012) (93)
- Nature of full-length HMGB1 binding to cisplatin-modified DNA. (2003) (92)
- Interaction of Platinum Antitumor Compounds with DNA (1990) (92)
- Synthesis and reactivity of binuclear tropocoronand and related organocopper(I) complexes. Catalytic enantioselective conjugate addition of Grignard reagents to 2-cyclohexen-1-one (1988) (91)
- MS4, a seminaphthofluorescein-based chemosensor for the ratiometric detection of Hg(II) (2005) (91)
- Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication. (1990) (91)
- Structure of the soluble methane monooxygenase regulatory protein B. (1999) (91)
- Visualization of peroxynitrite-induced changes of labile Zn2+ in the endoplasmic reticulum with benzoresorufin-based fluorescent probes. (2013) (90)
- The HMG-domain protein Ixr1 blocks excision repair of cisplatin-DNA adducts in yeast. (1996) (90)
- Synthesis, characterization, and cytotoxicity of platinum(IV) carbamate complexes. (2011) (90)
- Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. (2007) (90)
- 2,4,6-Tris(2-pyrimidyl)- and 2,4,6-tris(2-pyridyl)-1,3,5-triazines hydrolyze in the presence of copper(II) to form a novel bis(aryl)carboximidato chelate complex (1976) (90)
- The zinspy family of fluorescent zinc sensors: syntheses and spectroscopic investigations. (2004) (90)
- Detecting and understanding the roles of nitric oxide in biology. (2010) (89)
- Component interactions in the soluble methane monooxygenase system from Methylococcus capsulatus (Bath). (1999) (89)
- Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc (2015) (89)
- Conjugated polymer-based fluorescence turn-on sensor for nitric oxide. (2005) (89)
- Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells. (2012) (88)
- Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA? (2007) (88)
- The antitumor drug cis-dichlorodiammineplatinum forms an intrastrand d(GpG) crosslink upon reaction with [d(ApGpGpCpCpT)]2 (1982) (88)
- Solvolysis reactions of cis- And trans-diamminedichloroplatinum (II) in dimethyl sulfoxide. Structural characterization and DNA binding of trans-[Pt(NH3)2(Me2SO)Cl]+ (1987) (87)
- Reactivity of mu-hydroxodizinc(II) centers in enzymatic catalysis through model studies. (2000) (87)
- AMPA receptor inhibition by synaptically released zinc (2015) (87)
- Conjugation of vitamin E analog α-TOS to Pt(IV) complexes for dual-targeting anticancer therapy. (2013) (86)
- Free Copper Ions in the Cell? (1999) (86)
- Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. (2001) (86)
- cis-Diamminedichloroplatinum(II) binds in a unique manner to oligo(dG).oligo(dC) sequences in DNA - a new assay using exonuclease III (1981) (86)
- Generation, translocation, and action of nitric oxide in living systems. (2011) (86)
- Enantioselective conjugate addition of Grignard reagents to enones catalyzed by chiral cuprate complexes (1990) (85)
- Tools and Tactics for the Optical Detection of Mercuric Ion (2008) (85)
- Crystal structures of two titanium tartrate asymmetric epoxidation catalysts (1984) (84)
- Identification by NMR Spectroscopy of Residues at Contact Surfaces in Large, Slowly Exchanging Macromolecular Complexes (1999) (84)
- At last--the crystal structure of urease. (1995) (84)
- MODELS OF THE REDUCED FORMS OF POLYIRON-OXO PROTEINS : AN ASYMMETRIC, TRIPLY CARBOXYLATE BRIDGED DIIRON(II) COMPLEX AND ITS REACTION WITH DIOXYGEN (1991) (84)
- Interaction of FACT, SSRP1, and the High Mobility Group (HMG) Domain of SSRP1 with DNA Damaged by the Anticancer Drug Cisplatin* (2001) (83)
- Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms. (2010) (83)
- Dinitrosyl iron complexes relevant to Rieske cluster nitrosylation. (2009) (83)
- Third row transition metals for the treatment of cancer (2015) (83)
- Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II). (1993) (83)
- Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis (2011) (82)
- Characterization of the arene-oxidizing intermediate in ToMOH as a diiron(III) species. (2007) (82)
- Transcription inhibition by platinum-DNA cross-links in live mammalian cells. (2010) (82)
- Mechanistic studies of a novel class of trisubstituted platinum(II) antitumor agents. (1991) (81)
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- Use of antibodies to probe the stereochemistry of antitumor platinum drug binding to deoxyribonucleic acid (1983) (66)
- Synthesis, structure, and magnetic and Moessbauer properties of mononuclear and asymmetric, oxo-bridged trinuclear iron(III) complexes of a new polyimidazole ligand (1987) (66)
- Amide Hydrolysis Effected by a Hydroxo-Bridged Dinickel(II) Complex: Insights into the Mechanism of Urease (1999) (66)
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- Synthesis and Characterization of Spin-Delocalized Carboxylate-Bridged Cu(I)−Cu(II) Mixed-Valence Complexes Having Only Oxygen Donor Ligands (1998) (61)
- SYNTHESIS AND STRUCTURE OF THE IMIDAZOLATE BRIDGED DICOPPER(II) ION INCORPORATED INTO A CIRCULAR CRYPTATE MACROCYCLE (1979) (61)
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- Transition metal hydroborate complexes. 10. Crystal and molecular structure of tris(tetrahydroborato)tris(tetrahydrofuran)yttrium(III) (1978) (60)
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- Carbynes generated from metal carbonyl and isocyanide complexes; intermediates in the reductive coupling of carbonyl and CNR ligands (1988) (59)
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- Characterization of a novel .mu.4-peroxide tetrairon unit of possible relevance to intermediates in metal-catalyzed oxidations of water to dioxygen (1989) (57)
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- A single HMG domain in high-mobility group 1 protein binds to DNAs as small as 20 base pairs containing the major cisplatin adduct. (1995) (56)
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- Chemical and spectroscopic characterization of cis-diammineplatinum .alpha.-pyridone blue in aqueous solution. Comparison with other platinum blues (1979) (55)
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- Redox properties of cis-diammineplatinum .alpha.-pyridone blue and related complexes. Synthesis, structure, and electrochemical behavior of cis-diammineplatinum(III) dimers with bridging .alpha.-pyridonate ligands (1983) (54)
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- Reactions of eight-coordinate metal cyanide complexes. I. Molybdenum(IV) and tungsten(IV) oxocyanide complexes (1967) (53)
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- Chemical and Structural Studies of Rhenium(V) Oxyhalide Complexes. II. M[ReX4O] and M[ReX4OL] Complexes from KReO4 (1966) (53)
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- Higher coordinate complexes. 23. Reductive coupling of carbon monoxide ligands to form coordinated bis(trimethylsiloxy)ethyne in seven-coordinate niobium(I) and tantalum(I) [M(CO)2(dmpe)2Cl] complexes (1987) (51)
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- Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations. (2013) (49)
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- Water affects the stereochemistry and dioxygen reactivity of carboxylate-rich diiron(II) models for the diiron centers in dioxygen-dependent non-heme enzymes. (2005) (48)
- DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA. (2000) (48)
- Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent. (2000) (48)
- Zinc-secreting Paneth Cells Studied by ZP Fluorescence (2006) (48)
- Sequencing and analysis of the Methylococcus capsulatus (Bath) soluble methane monooxygenase genes (2000) (48)
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- Immobilization, trapping, and anion exchange of perrhenate ion using copper-based tripodal complexes. (2011) (48)
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- Effects of DNA adduct structure and distribution on the mutagenicity and genotoxicity of two platinum anticancer drugs. (1994) (47)
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- Synthesis and structure of Fe(L'H)(NO)2, a tetracoordinate complex having a twelve-membered chelate ring, and its conversion to pentacoordinate FeL'(NO) through formal loss of "HNO" (L' = SCH2CH2NMeCH2CH2CH2NMeCH2CH2S-) (1980) (47)
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- Molecular mechanics modeling of oligonucleotide adducts of the antitumor drug cis‐diamminedichloroplatinum(II) (1987) (44)
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- Multiple heavy-atom reagents for macromolecular X-ray structure determination. Application to the nucleosome core particle. (1987) (43)
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- Platinum Binding to d(GpG) Target Sequences and Phosphorothioate Linkages in DNA Occurs More Rapidly with Increasing Oligonucleotide Length (1994) (42)
- Valence-Delocalized Diiron(II,III) Cores Supported by Carboxylate-Only Bridging Ligands (2000) (42)
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- Synthesis and molecular structure of bis(6-mercapto-9-benzylpurine)palladium(II)-dimethylacetamide (1974) (41)
- Electronic and vibrational spectroscopic analysis of the (.mu.-oxo)bis(.mu.-carboxylato)diiron(III) core: a study of [Fe2O(O2CCH3)2(TACN)2]2+ (1985) (41)
- Synthesis, isomer separation, and metal complexation studies of aza- and oxaphosphands, a class of hard/soft dinucleating phosphine macrocycles (1990) (41)
- Reinvestigation of 18-crown-6 ether/potassium superoxide solutions in Me2SO (1983) (41)
- Oxidative halogenation of cisplatin and carboplatin: synthesis, spectroscopy, and crystal and molecular structures of Pt(IV) prodrugs. (2014) (41)
- Cisplatin Sensitivity in Hmgb1−/− and Hmgb1+/+ Mouse Cells* (2003) (41)
- Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. (2010) (41)
- Anticancer Activity of Cisplatin and Related Complexes (1999) (41)
- Mechanism of nitric oxide reactivity and fluorescence enhancement of the NO-specific probe CuFL1. (2010) (41)
- Self assembly and dioxygen reactivity of an asymmetric, triply bridged diiron(II) complex with imidazole ligands and an open coordination site (1989) (41)
- HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts. (2000) (41)
- Theoretical prescription for reductive coupling of carbonyl or isocyanide ligands (1983) (40)
- Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand. (2003) (40)
- Enhanced binding of the TATA-binding protein to TATA boxes containing flanking cisplatin 1,2-cross-links. (2000) (40)
- {Generation of a mixed-valent Fe(III)Fe(IV) form of intermediate Q in the reaction cycle of soluble methane monooxygenase, an analog of intermediate X in ribonucleotide reductase R2 assembly} (1998) (40)
- Isocyanide Insertion Reactions with Organometallic Group 4 Tropocoronand Complexes: Formation of η2-Iminoacyl, Enediamido, η2-Imine, and μ-Imido Products (1997) (40)
- Characterization of a platinum pyrimidine blue: synthesis, structure, and physical properties of cis-diammineplatinum 1-methyluracil blue (1984) (40)
- Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA. (2008) (40)
- The State of the Art of Chemical Biology (2009) (40)
- Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. (2006) (39)
- X-ray crystal structure of alcohol products bound at the active site of soluble methane monooxygenase hydroxylase. (2001) (39)
- High-salt and low-salt models for kinked adducts of cis-diamminedichloroplatinum(II) with oligonucleotide duplexes (1986) (39)
- Mechanistic studies of the reductive coupling of carbon monoxide in seven-coordinate niobium(I) and tantalum(I) dicarbonyl complexes (1991) (39)
- Convenient, high-yield synthesis of (Et4N)2[Fe2OCl6] (1985) (39)
- An EPR study of the dinuclear iron site in the soluble methane monooxygenase from Methylococcus capsulatus (Bath) reduced by one electron at 77 K: the effects of component interactions and the binding of small molecules to the diiron(III) center. (1999) (39)
- Electron-transfer reactions of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath). (2001) (38)
- Synthetic Models of the Deoxy and Oxy Forms of the Non-Heme Dioxygen-Binding Protein Hemerythrin (1998) (38)
- New age determinations and the geology of the Kenya Rift-Kavirondo Rift junction, W Kenya (1979) (38)
- Cenozoic uplift and erosion of the Barents Sea — evidence from the Svalis Dome area (1993) (38)
- Repair shielding of platinum-DNA lesions in testicular germ cell tumors by high-mobility group box protein 4 imparts cisplatin hypersensitivity (2017) (38)
- Surface and Electrostatic Contributions to DNA-Promoted Reactions of Platinum(II) Complexes with Short Oligonucleotides: A Kinetic Study (1995) (38)
- A pH-dependent superoxide dismutase activity for zinc-free bovine erythrocuprein. Reexamination of the role of zinc in the holoprotein. (1982) (38)
- Trinuclear, oxo-centered mixed-valence iron complex with unprecedented carboxylate coordination: [Fe3O(O2CCH3)6(TACN)].cntdot.2CHCl3 (1991) (37)
- Tris(2-pyridylmethyl)amine (TPA) as a membrane-permeable chelator for interception of biological mobile zinc. (2013) (37)
- Study of the binding of cis- and trans-dichlorodiammineplatinum(II) to calf thymus DNA by extended x-ray absorption fine structure spectroscopy (1978) (37)
- Functional mimic of dioxygen-activating centers in non-heme diiron enzymes: mechanistic implications of paramagnetic intermediates in the reactions between diiron(II) complexes and dioxygen. (2002) (37)
- Selective fluorescence detection of nitroxyl over nitric oxide in buffered aqueous solution using a conjugated metallopolymer (2007) (37)
- The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins. (2010) (36)
- Chemical and Structural Studies of Rhenium(V) Oxyhalide Complexes. III. The Crystal and Molecular Structure of Tetraphenylarsonium Oxotetrabromoacetonitrilerhenate(V) (1966) (36)
- Oxidation of sulfide, phosphine, and benzyl substrates tethered to N-donor pyridine ligands in carboxylate-bridged diiron(II) complexes. (2004) (36)
- Pentamethylcyclopentadienyl and cyclopentadienyl tantalum and niobium calixarene compounds and their water and acetonitrile inclusion complexes (1995) (36)
- Pentacoordinate cobalt(III) thiolate and nitrosyl tropocoronand compounds. (2001) (36)
- Binding of [(dien)PtCl]Cl to poly(dG-dC).poly(dG-dC) facilitates the B→Z conformational transition (1982) (36)
- Carboxylate- and Phosphate Ester-Bridged Dimagnesium(II), Dizinc(II), and Dicalcium(II) Complexes. Models for Intermediates in Biological Phosphate Ester Hydrolysis (1996) (36)
- X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior. (2006) (36)
- Synthesis and characterization of [d(ApGpGpCpCpT)]2 and its adduct with the anticancer drug cis-diamminedichloroplatinum(II) (1988) (36)
- Synthesis and metal-binding properties of chelating fluorescein derivatives. (2003) (36)
- A Volatile Inorganic Salt, CS[Y(CF3COCHCOCF3)4] (1966) (36)
- Relationship of cis-diammineplatinum α-pyridone blue to other platinum blues. An x-ray photoelectron study (1978) (35)
- Current Challenges of Modeling Diiron Enzyme Active Sites for Dioxygen Activation by Biomimetic Synthetic Complexes (2010) (35)
- Reactivity pathways for nitric oxide and nitrosonium with iron complexes in biologically relevant sulfur coordination spheres. (2007) (35)
- Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1. (2011) (35)
- Factors influencing the stereochemistry of four-coordinate copper(I)-phosphine complexes (1971) (35)
- Diiron Oxidation State Control of Substrate Access to the Active Site of Soluble Methane Monooxygenase Mediated by the Regulatory Component (2014) (35)
- Catalytic oxidative ring opening of THF promoted by a carboxylate-bridged diiron complex, triarylphosphines, and dioxygen. (2004) (35)
- Reductive coupling of carbon monoxide and alkyl isocyanide ligands in early transition metal complexes : a review (1990) (35)
- Binding of cis- and trans-diamminedichloroplatinum(II) to deoxyribonucleic acid exposes nucleosides as measured immunochemically with anti-nucleoside antibodies. (1986) (35)
- Consequences of cisplatin binding on nucleosome structure and dynamics. (2010) (35)
- Copper(II) tropocoronands: synthesis, structure, and properties of mononuclear complexes (1985) (35)
- Evaluating the identity and diiron core transformations of a (μ-oxo)diiron(III) complex supported by electron-rich tris(pyridyl-2-methyl)amine ligands. (2012) (35)
- High-throughput synthesis and screening of platinum drug candidates (2000) (35)
- Conjugated metallopolymers for fluorescent turn-on detection of nitric oxide. (2006) (35)
- Chemical and biological studies of the major DNA adduct of cis-diamminedichloroplatinum(II), cis-[Pt(NH3)2(d(GpG]], built into a specific site in a viral genome. (1988) (35)
- DNA promotes the reaction of cis-diamminedichloroplatinum(II) with the exocyclic amino groups of ethidium bromide (1988) (35)
- Aza- and oxaphosphands, a new class of hard/soft binucleating phosphine macrocycles (1986) (35)
- Cooperative binding of a platinum metallointercalation reagent to poly(A).poly(U). (1979) (34)
- Kinetic Studies of Reactions of Dioxygen with Carboxylate-Bridged Diiron(II) Complexes Leading to the Formation of (μ-Oxo)diiron(III) Complexes (1997) (34)
- Synthesis and 1H NMR spectroscopic characterization of trans-[Pt(NH3)2[d(ApGpGpCpCpT)-N7-A(1),N7-G(3)]]. (1987) (34)
- Rapid fluorescence-based reporter-gene assays to evaluate the cytotoxicity and antitumor drug potential of platinum complexes. (1999) (34)
- Enhanced stability of the imidazolate-bridged dicopper(II) ion in a binucleating macrocycle (1980) (34)
- Mixed-Valence Cu(I)-Cu(II) and Heterodimetallic Cu(I)-M(II) Bis(carboxylate-bridged) Complexes: Structural, Electrochemical, and Spectroscopic Investigations. (1998) (34)
- DNA Intercalation Facilitates Efficient DNA-Targeted Covalent Binding of Phenanthriplatin. (2019) (34)
- Sulfur-bridged binuclear iron(II) complexes. Effect of ligand constraints on their physical properties; reactions with carbon monoxide and alkyl isocyanides (1976) (34)
- A far-red emitting probe for unambiguous detection of mobile zinc in acidic vesicles and deep tissue (2015) (34)
- Mutational and structural analyses of the regulatory protein B of soluble methane monooxygenase from Methylococcus capsulatus (Bath). (1999) (34)
- Synthesis and characterization of Cu(2)(I,I), Cu(2)(I,II), and Cu(2)(II,II) compounds supported by two phthalazine-based ligands: influence of a hydrophobic pocket. (2004) (34)
- Heavy-metal complexes of 2,4,6-tris(2-pyrimidyl)-1,3,5-triazine. Structure of a dilead derivative (1977) (34)
- Illuminating mobile zinc with fluorescence from cuvettes to live cells and tissues. (2012) (34)
- NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath). (2004) (34)
- Design and Synthesis of Multidentate Dinucleating Ligands Based on 1,8-Naphthyridine (2000) (34)
- Characterization of a peroxodiiron(III) intermediate in the T201S variant of toluene/o-xylene monooxygenase hydroxylase from Pseudomonas sp. OX1. (2009) (34)
- Light-Induced N2O Production from a Non-heme Iron–Nitrosyl Dimer (2014) (34)
- Correlation between metal-metal distances and optical spectroscopy in the platinum blues: synthesis, crystal structure, and electronic spectrum of ethylenediamine platinum .alpha.-pyridone blue (1984) (34)
- EFFECTS OF A BRIDGING DICARBOXYLATE LIGAND ON THE SYNTHESIS AND PHYSICAL PROPERTIES OF (MU -OXO-)BIS(MU -CARBOXYLATO)DIIRON(III) COMPLEXES (1991) (34)
- Studies of the Soluble Methane Monooxygenase Protein System: Structure, Component Interactions, and Hydroxylation Mechanism (1995) (33)
- A CRYSTALLINE PLATINUM BLUE: ITS MOLECULAR STRUCTURE, CHEMICAL REACTIVITY, AND POSSIBLE RELEVANCE TO THE MODE OF ACTION OF ANTITUMOR PLATINUM DRUGS * (1978) (33)
- Analogues of Zinpyr-1 provide insight into the mechanism of zinc sensing. (2006) (33)
- Kinetic Studies of the TATA-binding Protein Interaction with Cisplatin-modified DNA* 210 (2001) (33)
- Phthalazine-based dinucleating ligands afford dinuclear centers often encountered in metalloenzyme active sites. (2001) (33)
- Analysis of substrate access to active sites in bacterial multicomponent monooxygenase hydroxylases: X-ray crystal structure of xenon-pressurized phenol hydroxylase from Pseudomonas sp. OX1. (2011) (33)
- Synthesis and structure of the imidazolate-bridged dicopper(II) ion in two binucleating macrocycles (1984) (33)
- Diiron Complexes of 1,8-Naphthyridine-Based Dinucleating Ligands as Models for Hemerythrin (2000) (33)
- Higher coordinate complexes. Part 22. Synthesis and reactions of seven-coordinate technetium and rhenium alkyl isocyanide complexes (1985) (32)
- Structure of heptakis(tert-butyl isocyanide)molybdenum(II) hexafluorophosphate, a seven-coordinate complex with C2.nu. monocapped trigonal prismatic geometry (1975) (32)
- Catalytic oxidation by a carboxylate-bridged non-heme diiron complex. (2002) (32)
- Synthesis of isomerically pure carboxylate- and sulfonate-substituted xanthene fluorophores (2005) (32)
- Active site threonine facilitates proton transfer during dioxygen activation at the diiron center of toluene/o-xylene monooxygenase hydroxylase. (2010) (32)
- Binding interaction of HMGB4 with cisplatin-modified DNA. (2012) (32)
- Isolation and characterization of cDNA clones encoding the Drosophila homolog of the HMG-box SSRP family that recognizes specific DNA structures. (1993) (32)
- Magnetic exchange interactions in imidazolate bridged copper(II) complexes (1977) (32)
- Preparation and X-ray structures of metal-free, dicobalt and dimanganese forms of soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath). (2004) (31)
- Aminoguanidinium Hydrolysis Effected by a Hydroxo-Bridged Dicobalt(II) Complex as a Functional Model for Arginase and Catalyzed by Mononuclear Cobalt(II) Complexes (1998) (31)
- Synthesis and electrochemical studies of diiron complexes of 1,8-naphthyridine-based dinucleating ligands to model features of the active sites of non-heme diiron enzymes. (2001) (31)
- Alteration and activation of sequence-specific cleavage of DNA by bleomycin in the presence of the antitumor drug cis-diamminedichloroplatinum(II). (1983) (31)
- Synthesis, Photophysics, Electrochemistry and Electrogenerated Chemiluminescence of a Homologous Set of BODIPY-Appended Bipyridine Derivatives. (2011) (31)
- Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal form. (1990) (31)
- X-ray Absorption Spectroscopic Studies of the Diiron Center in Methane Monooxygenase in the Presence of Substrate and the Coupling Protein of the Enzyme System (1995) (31)
- Molecular Aspects of Platinum-DNA Interactions (1993) (31)
- Synthesis and characterization of {Ni(NO)}10 and {Co(NO)2}10 complexes supported by thiolate ligands. (2008) (31)
- A novel hexairon(III) aggregate prepared from a basic iron(III) benzoate. Possible building blocks in ferritin core formation (1988) (31)
- Multiple States of Stalled T7 RNA Polymerase at DNA Lesions Generated by Platinum Anticancer Agents* (2003) (31)
- Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin. (2016) (31)
- Current Status and Mechanism of Action of Platinum‐Based Anticancer Drugs (2011) (31)
- Synthetic analogue of the [Fe(2)(mu-OH)(2)(mu-O(2)CR)](3+) core of soluble methane monooxygenase hydroxylase via synthesis and dioxygen reactivity of carboxylate-bridged diiron(II) complexes. (2002) (30)
- SYNTHESIS AND STRUCTURE OF THE IMIDAZOLATE‐BRIDGED DICOPPER(II) ION IN TWO BINUCLEATING MACROCYCLES (1984) (30)
- Binding of the antitumor drug platinum uracil blue to closed and nicked circular duplex DNAs. (1978) (30)
- Trinuclear Zn(II) and Cu(II) homo and heterotrimetallic complexes involving D-glucopyranosyl and biscarboxylate bridging ligands. A substrate binding model of xylose isomerases. (2001) (30)
- Structural and Spectroscopic Comparisons between (μ-Oxo)- and (μ-Hydroxo)bis(μ-carboxylato)diiron(III) Complexes That Contain All-Oxygen-Donor Ligands (1999) (30)
- Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices (2014) (30)
- Zinc-Containing Carboxylate-Bridged Heterodimetallic Complexes and Their Reactions with Phosphodiester Ligands (1996) (30)
- Synthesis and stabilization of tantalum-coordinated dihydroxyacetylene from two reductively coupled carbon monoxide ligands (1988) (30)
- Electronic Structure and Optical Spectrum of cis-Diammineplatinum α-Pyridone Blue: Metal-Metal Bonding and Charge Transfer in a Four-Atom Pt(2.25) Chain (1984) (30)
- Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. (2004) (30)
- Modulation of Ligand Fluorescence by the Pt(II)/Pt(IV) Redox Couple. (2012) (30)
- Convenient, high-yield synthesis of tetraethylammonium (.mu.-oxo)bis[trichloroferrate(III)] (Et4N)2[Fe2OCl6]) (1985) (30)
- Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework. (2011) (30)
- Synthesis, Characterization, and Magnetic Studies of Two Novel Isostructural Pentanuclear Iron(II) Complexes (1997) (30)
- Oxygen Kinetic Isotope Effects in Soluble Methane Monooxygenase* (2001) (30)
- HIGHER COORDINATE CYANIDE AND ISOCYANIDE COMPLEXES. 8. SYNTHESIS AND STRUCTURE OF DIIODODICARBONYLTRIS(TERT-BUTYL ISOCYANIDE)TUNGSTEN(II), AN EXAMPLE OF THE 4:3 PIANO STOOL SEVEN-COORDINATE GEOMETRY (1979) (30)
- Isomerization of binuclear amidate-bridged platinum(II) amine complexes: A 195Pt NMR investigation (1989) (30)
- Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. (2004) (29)
- Preparation and Spectra of Some Adducts of the Nonachlorotrirhenium and Nonabromotrirhenium Groups; Evidence for the Re3Br9 Group (1965) (29)
- Ethidium bromide changes the nuclease-sensitive DNA binding sites of the antitumor drug cis-diamminedichloroplatinum(II). (1982) (29)
- Medicinal Inorganic Chemistry (2005) (29)
- STRUCTURE OF URANIUM BOROHYDRIDE BY SINGLE-CRYSTAL X-RAY DIFFRACTION. (1972) (29)
- Reactions of eight-coordinate metal cyanide complexes. III. Synthesis and structure of iodohexakis(tert-butyl isocyanide)molybdenum(II) iodide (1972) (29)
- Acetate-bridged platinum(III) complexes derived from cisplatin. (2012) (29)
- Electron Transfer Control in Soluble Methane Monooxygenase (2014) (28)
- Expression and characterization of ferredoxin and flavin adenine dinucleotide binding domains of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath). (2002) (28)
- Raman and infrared spectra of hafnium tetrakis(tetrahydroborate) and hafnium tetrakis(tetrahydroborate-d16). Evidence for hafnium-boron bonding (1975) (28)
- Intermolecular electron-transfer reactions in soluble methane monooxygenase: a role for hysteresis in protein function. (2005) (28)
- Mononuclear complexes of cis-diammineplatinum(II) and -(IV) with .alpha.-pyridone. Structures of cis-[Pt(NH3)2(C5H4NOH)2]Cl2, mer-[Pt(NH3)2(C5H4NO)Cl3], and cis-[Pt(NH3)2(C5H4NOH)Cl](NO3) (1983) (28)
- Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division (2020) (28)
- Anion binding to the four-copper form of bovine erythrocyte superoxide dismutase: Mechanistic implications. (1981) (28)
- Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites. (2011) (28)
- Tracking a defined route for O2 migration in a dioxygen-activating diiron enzyme (2011) (28)
- Platinum binds selectively to phosphorothioate groups in mono- and polynucleotides: a general method for heavy metal staining of specific nucleotides. (1976) (28)
- Proteins that bind to and mediate the biological activity of platinum anticancer drug-DNA adducts. (1996) (27)
- The Preparation and Characterization of Compounds Containing both Hexabromorhenate(IV) and the Trirhenium Non abromide Group (1965) (27)
- Dimolybdenum(II) Calixarene Complexes: Synthesis, Structure, Raman Spectroscopy, and Bonding (1995) (27)
- Nitric Oxide‐Induced Fluorescence Enhancement by Displacement of Dansylated Ligands from Cobalt (2006) (27)
- A tetranitrosyl [4Fe-4S] cluster forms en route to Roussin's black anion: nitric oxide reactivity of [Fe4S4(LS3)L'](2-). (2014) (27)
- Intramolecular conjugate addition reactions via organozinc compounds (1993) (27)
- Kinetic, spectroscopic, and structural evidence for carbene-carbyne intermediates in carbyne/CO coupling (1993) (27)
- Dioxygen-initiated oxidation of heteroatomic substrates incorporated into ancillary pyridine ligands of carboxylate-rich diiron(II) complexes. (2006) (27)
- Metal binding by thionucleosides. (1972) (27)
- Transition metal hydroborate complexes. VI. Solid-state structure of .mu.-bis(cyanotrihydroborato)-tetrakis(triphenylphosphine)dicopper(I) (1974) (27)
- (&mgr;-Oxo)bis(&mgr;-carboxylato)bis(2,2'-bipyridyl)bis(X)diiron(III) Complexes, X = NCS(-), NCSe(-), and N(3)(-): Synthetic Models of Pseudohalide Derivatives of Carboxylate-Bridged Diiron Proteins. (1997) (27)
- Transition metal hydroborate complexes. IV. Cyanotrihydroborate complexes of the Group Ib metals (1972) (26)
- A planar carboxylate-rich tetraironII complex and its conversion to linear triironII and paddlewheel diironII complexes. (2007) (26)
- Cisplatin damage overrides the predefined rotational setting of positioned nucleosomes. (2007) (26)
- Luminescent properties of water-soluble conjugated metallopolymers and their application to fluorescent nitric oxide detection. (2006) (26)
- Quantum chemical studies of methane monooxygenase: comparision with P450. (2002) (26)
- μ‐Hydroxobis(μ‐formato)hexaaquadichromium(III), an Intermediate in the Formation of Basic Chromium Carboxylates (1990) (26)
- A dual-targeting, p53-independent, apoptosis-inducing platinum(II) anticancer complex, [Pt(BDI(QQ))]Cl. (2014) (26)
- The geology of the Dibba zone, northern Oman mountains; a preliminary study (1982) (26)
- Synthesis and structure of a bis[terpyridineplatinum(II)] complex and its evaluation as a metallointercalator (1980) (25)
- AUTOMATED SOLID-PHASE SYNTHESIS OF SITE-SPECIFICALLY PLATINATED OLIGODEOXYRIBONUCLEOTIDES (1996) (25)
- Site-specifically platinated DNA, a new probe of the biological activity of platinum anticancer drugs (1986) (25)
- The Chemistry of Platinum in the +3 Oxidation State (1985) (25)
- Sulfur-Bridged Dimeric Complexes of Iron (III) (1970) (25)
- Membrane-Permeable Mn(III) Complexes for Molecular Magnetic Resonance Imaging of Intracellular Targets. (2016) (25)
- Addition of a Second Binding Site Increases the Dynamic Range but Alters the Cellular Localization of a Red Fluorescent Probe for Mobile Zinc (2014) (25)
- Crystal Structure Determination of a (μ-Amido)(μ-hydroxo)(μ-superoxo)dicobalt(III) Complex from the Werner Collection (2001) (25)
- Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}[superscript 2]+-d(GpG) crosslink at 1.77 [Angstrom] resolution (2010) (25)
- Synthesis and physical properties of hexakis(isothiocyanato)technetate(III) and -(IV) complexes. Structure of the [Tc(NCS)6]3- ion (1980) (25)
- Higher coordinate complexes. 23. Reductive coupling of isocyanide ligands in seven-coordinate molybdenum(II) mixed isocyanide bipyridine complexes (1986) (25)
- Crystal and molecular structure of bis(ethyl thioxanthato)-.mu.-bis(ethyl thioxanthato)-.mu.'-bis(ethylthio)diiron(III) (1970) (25)
- Reactions of eitht-coordinate metal cyanide complexes. IV. Synthesis and spectroscopic and structural properties of tetracyanotetrakis(alkyl isocyanide)molybdenum(IV) complexes (1972) (25)
- Iron sulfur coordination compounds and proteins (1973) (24)
- Structure, Recognition, and Processing of Cisplatin-DNA Adducts (1999) (24)
- STRUCTURE OF THE IMIDAZOLATE-BRIDGED DICOPPER(II) CATION CU2(BPIM)3+ (1980) (24)
- Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase. (2007) (24)
- Influence of tetraazamacrocyclic ligands on the nitric oxide reactivity of their cobalt(II) complexes. (2012) (24)
- Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models. (2018) (24)
- Achieving Reversible Sensing of Nitroxyl by Tuning the Ligand Environment of Azamacrocyclic Copper(II) Complexes. (2016) (24)
- Molecular structure and ligand-exchange reactions of trichlorotris(tert-butyl isocyanide)vanadium(III). Synthesis of the hexakis(tert-butyl isocyanide)vanadium(II) cation (1980) (24)
- Formation of highly functionalized metal-bound acetylenes by reductive coupling of carbon monoxide and methyl isocyanide ligands (1992) (24)
- Speciation of Phenanthriplatin and Its Analogs in the Core of Tobacco Mosaic Virus. (2018) (24)
- Synthesis and Characterization of Carboxylate-Rich Complexes Having the {Fe2(μ-OH)2(μ-O2CR)}3+ and {Fe2(μ-O)(μ-O2CR)}3+ Cores of O2-Dependent Diiron Enzymes (2004) (24)
- Solid-phase synthesis provides a modular, lysine-based platform for fl uorescent discrimination of nitroxyl and biological thiols † (2015) (23)
- Synthesis and study of monomeric and sulfur-bridged dimeric cobalt(III) thioxanthate complexes and their relation to sulfur-bridged iron(III) dimers (1972) (23)
- Preparation and structural characterization of six-coordinate iron(III) complexes containing the Fe-S-S linkage (1968) (23)
- Cisplatin sensitivity in Hmbg1-/- and Hmbg1+/+ mouse cells. (2003) (23)
- Structure determinations of halotetrakis(tert-butyl isocyanide)((N,N'-di-tert-butyldiamino)acetylene)molybdenum(II) complexes (1981) (23)
- Synthesis of PDK, a novel porphyrin-linked dicarboxylate ligand. (2000) (23)
- Magnetic Properties of Dodecanuclear Mixed Valence Iron Clusters (1996) (23)
- Higher coordinate cyanide and isocyanide complexes. 7. Synthesis and characterization of seven-coordinate molybdenum(II) and tungsten(II) isocyanide complexes (1978) (23)
- Carboxylate bridge exchange reactions in the {Fe2O(O2CR)2}2+ core. Synthesis, structure, and properties of phosphodiester-bridged complexes (1985) (23)
- Stopped-flow fluorescence studies of HMG-domain protein binding to cisplatin-modified DNA. (2000) (23)
- Facile Synthesis of Isomerically Pure cis‐Dichlorodiammineplatinum(II), Cisplatin (2007) (23)
- Iron tricarbonyl cyclooctatetraene complexes (1967) (23)
- Synthesis, structure, and properties of an imidazolate-bridged copper(II)-cobalt(III) complex (1981) (23)
- Plateau phonolite lava flows, Kenya (1973) (22)
- Visualizing inhibition of nucleosome mobility and transcription by cisplatin-DNA interstrand crosslinks in live mammalian cells. (2013) (22)
- Stereochemical control of reactivity in cobalt(III) alkyl complexes of the tropocoronand ligand system (1993) (22)
- Synthesis, structure, and reactions of rhenium aminocarbyne complexes formed from [ReCl2(CNR)3(PMePh2)2]+ (R = tert-Bu or Me) cations under reductive coupling conditions (1989) (22)
- Effect of axial ligands on the platinum-platinum bond in binuclear .alpha.-pyridonate-bridged platinum(III) complexes. Structures of [X(NH3)2Pt(C5H4NO)2Pt(NH3)2X](NO3)2.H2O, X = NO3, NO2 (1982) (22)
- Models of the oxidized forms of polyiron oxo proteins: synthetic routes to (μ-oxo)bis(μ-carboxylato)diiron(III) complexes with neutral monodentate and bidentate capping ligands (1992) (22)
- Cisplatin and Related Drugs (2014) (21)
- Preparation and structural characterization of a novel hexanuclear complex of platinum(II) with 2-aminoethanethiolate (1986) (21)
- Structural and spectroscopic studies of valence-delocalized diiron(II,III) complexes dupported by carboxylate-only bridging ligands. (2002) (21)
- Nitrosyl transfer from manganese to iron in tropocoronand complexes. (2000) (21)
- Visualization of polymercurimethane-labeled for bacteriophage in the scanning transmission electron microscope. (1979) (21)
- Mechanistic Studies of the Reaction of Dioxygen with Dinuclear Iron(II) Compounds to Form (.mu.-Peroxo)diiron(III) Complexes (1994) (21)
- Photoluminescent DNA binding and cytotoxic activity of a platinum(II) complex bearing a tetradentate β-diketiminate ligand. (2012) (21)
- Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage. (2016) (21)
- MONO- AND DINUCLEAR ZINC COMPLEXES OF XDK, H2XDK=M-XYLENEDIAMINE BIS(KEMP'S TRIACID IMIDE), AND THEIR REACTION WITH PHOSPHATE ESTERS (1995) (21)
- Design and synthesis of a novel triptycene-based ligand for modeling carboxylate-bridged diiron enzyme active sites. (2011) (21)
- X-Ray crystal structure of a 2:2 chloroterpyridineplatinum(II)–adenosine-5′-monophosphate intercalation complex (1977) (21)
- Transition metal hydroborate complexes. 9. Preparation, properties, and structure of di-.mu.-cyanotrihydroborato-bis(2,2',2''-triaminotriethylamine) dinickel(II) tetraphenylborate (1977) (21)
- Fast atom bombardment and high performance tandem mass spectrometry of platinum(II) oligodeoxyribonucleotide fragments (1992) (21)
- Carboxylate-bridged diiron(II) complexes with a sterically hindered phthalazine ligand (2002) (21)
- Synthesis, characterization, and photophysical properties of three platinum(II) complexes bearing fluorescent analogues of the Di-2-pyridylmethane ligand. (2010) (21)
- Reactions of homoleptic (alkyl isocyanide)molybdenum(II) cations [Mo(CNR)7]2+ with 2,2'-bipyridine and related ligands (N-N). Substitution chemistry and dealkylation to form cyano-bridged complexes of the type [{Mo(CNCMe3)4(N-N)}2(.mu.-CN)](PF6)3 (1983) (21)
- Higher coordinate cyanide and isocyanide complexes. Part 12. Dealkylation and reductive coupling of tert-butyl isocyanide ligands in heptakis(tert-butyl isocyanide)molybdenum(II). Structure of cyanotetrakis(tert-butyl isocyanide)((N,N'-di-tert-butyldiamino)acetylene)molybdenum(II) tetraphenylborate (1981) (20)
- Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV. (2009) (20)
- Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations (2018) (20)
- Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission (2015) (20)
- Peptide-Based, Two-Fluorophore, Ratiometric Probe for Quantifying Mobile Zinc in Biological Solutions (2014) (20)
- The Quiet Revolution In Chemistry (2000) (20)
- Chemical synthesis: The art of chemistry (2002) (20)
- Higher coordinate cyanide and isocyanide complexes. Part 18. Electrochemical studies of seven-coordinated isocyanide complexes of molybdenum(II) and tungsten(II) (1982) (20)
- Synthesis, characterization, and dioxygen reactivity of tetracarboxylate-bridged Diiron(II) complexes with coordinated substrates. (2003) (20)
- Domain Engineering of the Reductase Component of Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath)* (2004) (20)
- Mechanistic studies of reactions of peroxodiiron(III) intermediates in T201 variants of toluene/o-xylene monooxygenase hydroxylase. (2011) (20)
- ESEEM and ENDOR Magnetic Resonance Studies of the Non-Kramers Doublet in the Integer-Spin Diiron(II) Forms of Two Methane Monooxygenase Hydroxylases and Hemerythrin Azide (1994) (20)
- Synthesis and NMR structural studies of the adduct of trans-diamminedichloroplatinum(II) with the DNA fragment d(GpCpG) (1987) (20)
- Synthesis, Structure, and Reactivity of (.mu.-Oxo)bis(.mu.-carboxylato)diiron(III) Complexes of a Dinucleating Dicarboxylate Ligand, a Kinetically Stable Model for Non-Heme Diiron Protein Cores (1994) (20)
- Tuning of Electronic Properties and Reactivity in Four-Coordinate Cobalt(III) Complexes by the Tetraazamacrocyclic Tropocoronand Ligand. (1997) (20)
- Ferromagnetic versus Antiferromagnetic Exchange in Five Structurally Analogous Carboxylate-Bridged Trinuclear Ferrous Complexes (1995) (20)
- Water-dependent reactions of diiron(II) carboxylate complexes. (2004) (20)
- Tropocoronands ad binucleating ligands. Synthesis, structure, and properties of a (.mu.-acetato)(.mu.-methoxo)dicopper(II) derivative (1985) (20)
- Higher coordinate cyanide and isocyanide complexes. 11. Structural studies of three seven-coordinate isocyanide complexes of molybdenum(II) and tungsten(II) (1981) (20)
- Geometry of the [Y(CF3COCHCOCF6)4]-Ion. A New Eight-Coordinate Stereoisomer in the Dodecahedral Class (1966) (19)
- Synthesis and characterization of Zr(IV) and Hf(IV) tropocoronand complexes (1997) (19)
- Monodentate-bridged phosphodiester and sulfate complexes: structural insights into the biological activation of phosphodiesters, sulfate, and sulfate esters. (2000) (19)
- Synthesis and Structural Characterization of Low-Valent Group V Phosphine Complexes (1992) (19)
- A mechanism-based, solution-phase method for screening combinatorial mixtures of potential platinum anticancer drugs (1998) (19)
- Polymer-bound dirhodium tetracarboxylate films for fluorescent detection of nitric oxide. (2006) (19)
- HaloTag-based hybrid targetable and ratiometric sensors for intracellular zinc. (2020) (19)
- A general method for assembling (.mu.-oxo)bis(.mu.-carboxylato)diiron(III) complexes with labile terminal sites using a bridging dicarboxylate ligand (1989) (19)
- Direct ratiometric detection of nitric oxide with Cu(ii)-based fluorescent probes. (2017) (19)
- Reductive coupling of carbon monoxide with methyl isocyanide in a seven-coordinate niobium complex (1990) (19)
- Synthesis and characterization of seven-coordinate tantalum(I) and niobium(I) complexes with cis carbonyl and alkyl isocyanide ligands (1992) (19)
- Zinc Metalloneurochemistry: Physiology, Pathology, and Probes (2006) (19)
- A Dimeric Iron(III) Complex Containing Two Ethyl Mercaptide and Two Ethyl Thioxanthate Groups as Bridging Ligands (1969) (19)
- Transition metal borohydride complexes. I. The structure of borohydridobis(triphenylphosphine)copper(I) (1967) (19)
- Non-Kramers ESEEM of integer-spin diferrous carboxylate-bridged clusters in proteins (1997) (19)
- Dicopper(I) tropocoronands: synthesis, X-ray crystal structure, and spectral properties of neutral binuclear copper(I) complexes bridged by symmetrically substituted alkynes (1985) (19)
- Peptide Targeting of Fluorescein-Based Sensors to Discrete Intracellular Locales. (2014) (19)
- Platinum-195 NMR investigation of the head-to-head to head-to-tail isomerization of .alpha.-pyridonate-bridged ethylenediamineplatinum(II) dimer (1983) (19)
- ZINC AND CADMIUM TROPOCORONAND COMPLEXES: EFFECT OF METAL ION RADIUS ON MACROCYCLIC LIGAND TWIST AND FOLD (1997) (19)
- Aging-associated enzyme human clock-1: substrate-mediated reduction of the diiron center for 5-demethoxyubiquinone hydroxylation. (2013) (19)
- Synthesis of Unsymmetrical Vicinal Diols Using Titanium Aminotroponiminate Alkyl Complexes (1999) (18)
- K—Ar ages of alkaline igneous rocks in the northern Oman mountains, NE Arabia, and their relations to rifting, passive margin development and destruction of the Oman Tethys (1982) (18)
- MRI sensing based on the displacement of paramagnetic ions from chelated complexes. (2010) (18)
- Substrate binding and C-H bond activation in the soluble methane monooxygenase hydroxylase (1998) (18)
- Stereochemical and electronic spin state tuning of the metal center in the nickel(II) tropocoronands (1985) (18)
- Determination by X-ray absorption spectroscopy of the Fe-Fe separation in the oxidized form of the hydroxylase of methane monooxygenase alone and in the presence of MMOD. (2004) (18)
- Dicopper(I) carbonyl tropocoronands. Preparation, structural characteristics, and reactivity of neutral binuclear copper-carbonyl macrocyclic compounds (1987) (18)
- Non-heme mononitrosyldiiron complexes: importance of iron oxidation state in controlling the nature of the nitrosylated products. (2013) (18)
- Synthesis and spectroscopic studies of non-heme diiron(III) species with a terminal hydroperoxide ligand: models for hemerythrin. (2001) (18)
- α[subscript v]β[subscript 3] Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug (2012) (18)
- Structure of the Toluene/o-Xylene Monooxygenase Hydroxylase (2004) (18)
- Calixarene complexes of the molybdenum-molybdenum quadruple bond☆ (1995) (18)
- Carboxylate-Bridged Heterodimetallic Complexes (1994) (17)
- Tropocoronands, a new class of metal-complexing macrocycles derived from aminotroponeiminates (1983) (17)
- Phenanthriplatin Acts As a Covalent Poison of Topoisomerase II Cleavage Complexes. (2016) (17)
- Modeling features of the non-heme diiron cores in O2-activating enzymes through the synthesis, characterization, and oxidation of 1,8-naphthyridine-based complexes. (2003) (17)
- Reaction chemistry of [M(R3SiOCCOSiR3)(dmpe)2Cl] (M = tantalum, niobium): isolation and structural characterization of the first (dihydroxyacetylene)metal complexes and removal of the disiloxyacetylene ligand as an alkene (1991) (17)
- Addition of nitrosonium ion to mercaptide-bridged binuclear iron(II) and cobalt(II) complexes (1974) (17)
- Synthesis of Unsymmetrical Diolate, Oxametallacyclopentene, Amido-Alkoxide and Thiolato-Alkoxide Complexes Using Dialkyl and Diaryl Titanium Aminotroponiminate Complexes: A Route to Unsymmetrical Vicinal Diols (1999) (17)
- Fluorescence-based Nitric Oxide Detection (2005) (17)
- Versatile reactivity of a solvent-coordinated diiron(II) compound: synthesis and dioxygen reactivity of a mixed-valent Fe(II)Fe(III) species. (2014) (17)
- Synthesis and Structural Characterization of [Cr(t-C4H9HNC.tplbond.CNH-t-C4H9)(CN-t-C4H9)4I]I. Reductive Coupling of Isocyanide Ligands in a First Row Transition Metal Complex (1994) (17)
- Tuning the stereochemistry of pentacoordinate cobalt(III) halide complexes: a rare case of trigonal bipyramidal stereochemistry for cobalt(III) (1992) (17)
- Crystal and molecular structure of thio-p-toluoyldisulfidobis (dithio-p-toluato)iron(III) (1969) (17)
- Higher coordinate cyanide and isocyanide complexes. 14. Improved synthesis of seven-coordinate molybdenum(II) and tungsten(II) isocyanide complexes: dealkylation of coordinated tert-butyl isocyanide (1982) (17)
- Improvements in the Synthesis and Understanding of the Iodo-bridged Intermediate en Route to the Pt(IV) Prodrug Satraplatin. (2014) (17)
- Thiocyanate cleaves the imidazolate-bridged dicopper(II) center in a binucleating macrocycle to form the copper(II) thiocyanate complex [Cu2(SCN)4 .cntnd. A]. Model chemistry for superoxide dismutase (1984) (17)
- Component B binding to the soluble methane monooxygenase hydroxylase by saturation-recovery EPR spectroscopy of spin-labeled MMOB. (2002) (17)
- Specific Visualization of Nitric Oxide in the Vasculature with Two-Photon Microscopy Using a Copper Based Fluorescent Probe (2013) (17)
- EXAFS studies of binuclear iron complexes as models for hemerythrin and related proteins (1986) (17)
- Zinc released from olfactory bulb glomeruli by patterned electrical stimulation of the olfactory nerve. (2013) (17)
- Transition metal hydroborate complexes. VII. Preparation, properties, and structure of bis(cyanotrihydroborato)-1,1,4,7,7-pentamethyldiethylenetriaminecopper(II) (1974) (17)
- SpiroZin1: A Reversible and pH‐Insensitive, Reaction‐Based, Red‐Fluorescent Probe for Imaging Biological Mobile Zinc (2014) (17)
- Long-Range Distance Constraints in Platinated Nucleotides: Structure Determination of the 5' Orientational Isomer of cis-[Pt(NH3)(4-aminoTEMPO){d(GpG)}]+ from Combined Paramagnetic and Diamagnetic NMR Constraints with Molecular Modeling (1995) (16)
- Hydroxo-bridged Cubane-type tetrairon(II) clusters supported by sterically-hindered carboxylate ligands. (2001) (16)
- Iron substitution for sodium in a carboxylate-bridged, heterodinuclear sodium-iron complex. (2005) (16)
- The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH3)2(phenanthridine)Cl]NO3. (2018) (16)
- Synthesis and stereochemistry of .pi.-allylmonothio-.beta.-diketonatopalladium(II)-olefin insertion products (1973) (16)
- Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints (2020) (16)
- cis-[Pt(NH3)2(L)]2+/+ (L = Cl, H2O, NH3) binding to purines and CO: does pi-back-donation play a role? (2003) (16)
- Synthesis and properties of cationic molybdenum(IV) oxohaloisocyanide complexes (1974) (16)
- Synthesis and structure of a tetranuclear zinc(II) complex of N,N'-dimethyl-N,N'-bis(β-mercaptoethyl)ethylenediamine (1973) (16)
- Characterization of a Diiron(III) Peroxo Intermediate in the Reaction Cycle of Methane Monooxygenase Hydroxylase from Methylococcus capsulatus (Bath) J. Am. Chem. Soc. 1995, 117, 4997−4998 (1997) (16)
- COUPLING OF CARBON MONOXIDE TO ISOCYANIDES AND ENONES INDUCED BY ALKYL ZR(IV) AND HF(IV) TROPOCORONAND COMPLEXES (1997) (16)
- Consequences of HMG-Domain Protein Binding to Cisplatin-Modified DNA (1995) (15)
- Synthesis, structure, and magnetic properties of an asymmetric .mu.3-oxotriiron(III) complex: a new type of {Fe3O}7+ core (1985) (15)
- A Flexible Glutamine Regulates the Catalytic Activity of Toluene o-Xylene Monooxygenase (2014) (15)
- Synthesis, characterization, DNA binding properties, and solution thermochromism of platinum(II) complexes of the ethidium cation: Regiospecificity in a DNA-promoted reaction (1993) (15)
- Effect of ligand constraints on the geometry of two sulfur-bridged binuclear iron(II) complexes. Structures of bis {.mu.-[N,N'-dimethyl-N,N'-bis(.beta.-mercaptoethyl)ethylenediamine]}-diiron(II) and bis{.mu.-[N,N'-dimethyl-N,N'-bis(.beta.-mercaptoethyl)-1,3-propanediamine]}-diiron(II) (1974) (15)
- Mercury(II) binding to s4U in E. coli tRNA(Val). (1974) (15)
- Stereochemistry of imidazolate-bridged copper(II) complexes: [Cu2bpim(im)]2(NO3)4.3H2O, C44H50Cu4N20O15, [Cu(pip)]2(im)(NO3)3.2.5H2O, C29H34Cu2N11O11.5,[Cu(pmdt)]2(2-Meim)(ClO4)3, C22H51Cl3Cu2N8O12, and [Cu(pmdt)]2(Bzim)(ClO4)3.H2O, C25H53Cl3Cu2N8O13 (1984) (15)
- Preparation of mammalian expression vectors incorporating site-specifically platinated-DNA lesions. (2009) (15)
- Small Molecule Binding to the Mixed-Valent Diiron Center of Methane Monooxygenase Hydroxylase from Methylococcus capsulatus (Bath) as Revealed by ENDOR Spectroscopy (1998) (15)
- The interface of inorganic chemistry and biology. (2010) (15)
- Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn2+ allows tracking of lysosomal Zn2+ pools (2018) (15)
- Synthesis and properties of a novel oxo-bridged dinuclear iron(III) complex containing only oxygen donating ligands (1989) (15)
- The reactivity of well defined diiron(III) peroxo complexes toward substrates: addition to electrophiles and hydrocarbon oxidation. (1999) (15)
- Role of Ca2+ in the Control of H2O2-Modulated Phosphorylation Pathways Leading to eNOS Activation in Cardiac Myocytes (2012) (15)
- Structural Features of Covalently Cross-linked Hydroxylase and Reductase Proteins of Soluble Methane Monooxygenase as Revealed by Mass Spectrometric Analysis* (2003) (15)
- Synthesis and structure of [(η2-C5H5)Nb(CNCMe3)4Cl][NbOCl4(THF)].THF1.2 (1984) (15)
- Nuclear Magnetic Resonance Studies of Eight‐Coordinate β‐Diketonate Complexes Related to Laser Chelates (1966) (15)
- A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. (2018) (15)
- Carboxylate- and Phosphodiester-Bridged Dinuclear Magnesium(II) Complexes (1995) (15)
- Synthetic Methods for the Preparation of Platinum Anticancer Complexes (2014) (15)
- Cage Compounds Containing the Trirhenium(III) Cluster: Re3Br3(AsO4)2(DMSO)31 (1966) (15)
- Modeling features of the non-heme diiron cores in O-2-activating enzymes through the synthesis, characterization, and oxidation of 1,8-naphthyridine-based complexes (2003) (15)
- Solid-state structure of monothiodibenzoylmethanato-.pi.-methallylpalladium(II) (1969) (14)
- Interchain hydrogen-bonding interactions may facilitate translocation of K+ ions across the potassium channel selectivity filter, as suggested by synthetic modeling chemistry (2001) (14)
- A (.mu.-Oxo)bis(.mu.-carboxylato)diiron(III) Complex with a Tethered Phenoxyl Radical as a Model for the Active Site of the R2 protein of Ribonucleotide Reductase (1995) (14)
- Alkyne-bridged dicopper(I) complexes of the tropocoronand macrocycles (1987) (14)
- Synthesis and characterization of the pentacoordinate mononitrosyliron complexes Fe(NO)[SCH2CH2N(CH3)(CH2)nN(CH3)CH2CH2S], n = 2,3 (1977) (14)
- Carboxylate-Bridged Diiron(II) Complexes, Including a New Model for Reduced Methane Monooxygenase Hydroxylase and the R2 Protein of Ribonucleotide Reductase (1995) (14)
- Crystal and molecular structure of tris(tert-butyl thioxanthato)iron(III) (1972) (14)
- Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. (2007) (14)
- X-ray absorption spectroscopic study of the reduced hydroxylases of methane monooxygenase and toluene/o-xylene monooxygenase: differences in active site structure and effects of the coupling proteins MMOB and ToMOD. (2005) (14)
- Product binding to the diiron(III) and mixed-valence diiron centers of methane monooxygenase hydroxylase studied by (1,2)H and (19)F ENDOR spectroscopy. (2002) (14)
- Laser-induced photo-cross-linking of cisplatin-modified DNA to HMG-domain proteins. (2001) (14)
- SYNTHESIS AND STRUCTURE OF HEXAKIS(TERT-BUTYL ISOCYANIDE)VANADIUM(II) HEXACARBONYLVANADATE(-I) (1981) (14)
- 13C magnetic resonance investigation of mercury (II) binding to nucleosides and thiolated nucleosides in dimethyl sulfoxide. (1975) (13)
- Synthesis of bis(imidazole) metal complexes and their use in rapid NO detection and quantification devices. (2014) (13)
- Higher coordinate cyanide and isocyanide complexes. Part 17. Structure of a homoleptic seven coordinate molybdenum(II) aryl isocyanide complex, [Mo(CNPh)7](PF6)2 (1982) (13)
- An asymmetric imidazolate-bridged dicopper(II) complex (1980) (13)
- Synthesis and Characterization of Mononuclear, Pseudotetrahedral Cobalt(III) Compounds (2014) (13)
- Synthesis, structure, and properties of a mixed-valent triiron complex of tetramethyl reductic acid, an ascorbic acid analogue, and its relationship to a functional non-heme iron oxidation catalyst system. (2007) (13)
- Synthesis, Tuning of the Stereochemistry, and Physical Properties of Cobalt(II) Tropocoronand Complexes. (1995) (13)
- Electrophile-Promoted Carbyne-CO Coupling at a Tantalum Center (1994) (13)
- Structural flexibility within a sterically hindered ligand platform:: mononuclear iron(II) carboxylate complexes as subsite models for diiron(II) centers (2002) (13)
- Linear carbonyl-bridged, dinuclear tantalum siloxycarbyne complexes (1992) (13)
- Unusual redox and chemical properties of a sterically constrained N3CuII center. Preparation, structure, and solution studies of (nitrato)(1,4,7-triazacyclododecane)copper(II) nitrate (1984) (13)
- Tropocoronands: a versatile macrocyclic ligand system for mononuclear and binuclear metal complexes (1986) (13)
- Reversible binding of nitric oxide to an Fe(III) complex of a tetra-amido macrocycle. (2012) (13)
- Synthesis of diethynyltriptycene-linked dipyridyl ligands. (2005) (13)
- Influence of steric hindrance on the core geometry and sulfoxidation chemistry of carboxylate-rich diiron(II) complexes. (2007) (13)
- Higher coordinate cyanide and isocyanide complexes. 13. Crystal structure of the homoleptic seven-coordinate complex heptakis(tert-butyl isocyanide)chromium(II) hexafluorophosphate, [Cr(CN-t-Bu)7](PF6)2 (1982) (13)
- Synthesis and Characterization of (Aminotroponiminato)titanium(IV) Dialkyl Complexes: Control of Reactivity by Ligand Design (1999) (13)
- Zinc thiolate reactivity toward nitrogen oxides: insights into the interaction of Zn2+ with S-nitrosothiols and implications for nitric oxide synthase. (2012) (12)
- A Platinum(IV) Prodrug - Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain. (2020) (12)
- Synthesis, characterization, and reactivity of organometallic Zr(IV) carboxylate complexes (1998) (12)
- Physical and Chemical Studies of Bovine Erythrocyte Superoxide Dismutase (1977) (12)
- Reactions of the diiron(IV) intermediate Q in soluble methane monooxygenase with fluoromethanes. (2005) (12)
- Characterization of a synthetic peroxodiiron(III) protein model complex by nuclear resonance vibrational spectroscopy. (2011) (12)
- Synthesis and Characterization of a Novel Class of Dicopper(I) Bis(carboxylate)-Bridged Complexes (1997) (12)
- Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins A list of abbreviations can be found in Section 7. (2001) (12)
- Synthesis and fluxional properties of monothio-.beta.-diketonatorhodium(I) diolefin complexes (1972) (12)
- Mechanistic studies of the reductive coupling of isocyanides in seven-co-ordinate molybdenum complexes; X-ray crystal structures of [Mo(CNBut)6] and [Mo{CN(But)(SiMe2But)}(CNBut)5][O3SCF3] (1991) (12)
- Nuclear magnetic resonance study of the exchangeable histidine protons in bovine and wheat germ superoxide dismutases. (1980) (12)
- Platinum Anticancer Drugs (1995) (12)
- Tetrakis(acetoxymercuri)methane: a polymetallic reagent for labeling sulfur in nucleic acids. (1978) (12)
- Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexes. (2006) (12)
- Structural Chemistry of Platinum—DNA Adducts (1983) (12)
- Crystallization and preliminary X-ray analysis of the methane monooxygenase hydroxylase protein from Methylococcus capsulatus (Bath). (1992) (12)
- Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation. (1997) (11)
- Synthesis of fluorescein derivatives containing metal-coordinating heterocycles (2004) (11)
- SYNTHESIS, STRUCTURE, AND REACTIONS OF (MO(SNCL3)(CN-TERT-BU)6)((PH3B)2CN), CONTAINING A POTENTIALLY USEFUL NEW ANION FOR CRYSTALLIZATIONS (1981) (11)
- Singlet-Triplet Gaps of Cobalt Nitrosyls: Insights from Tropocoronand Complexes. (2015) (11)
- CRYSTAL AND MOLECULAR STRUCTURE OF TRANS-OXOCHLOROTETRAKIS(METHYL ISOCYANIDE)MOLYBDENUM(IV) TRIIODIDE (1976) (11)
- Complexes of a pendant phenoxyl radical ligand, including a new model for the ribonucleotide reductase R2 protein (1993) (11)
- Metal‐Based Turn‐On Fluorescent Probes for Sensing Nitric Oxide (2007) (11)
- SULFUR‐BRIDGED BINUCLEAR IRON(II) COMPLEXES. EFFECT OF LIGAND CONSTRAINTS ON THEIR PHYSICAL PROPERTIES, REACTIONS WITH CARBON MONOXIDE AND ALKYL ISOCYANIDES (1977) (11)
- Synthesis, structure determination, and stereoisomerism of dirhodium(I) tetracarbonyl tropocoronand complexes (1988) (11)
- SYNTHESIS AND TRIIRON COMPLEXES OF PDK, A NEW PORPHYRIN-LINKED DICARBOXYLATE LIGAND (1998) (11)
- Di- and tetra-bridged diiron(II) complexes with four terphenyl-derived carboxylates and two water molecules (2004) (11)
- High-Salt and Low-Salt Models for Kinked Adducts of cis-Diamminedichloroplatinum(II) with Oligonucleotide Duplexes. (1986) (11)
- Synthesis and solution behavior of some .pi.-allyl monothiodibenzoylmethanatopalladium(II) complexes (1972) (11)
- Synthesis and DNA binding properties of a cisplatin analog containing a tethered dansyl group (1992) (11)
- Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells (2020) (11)
- Oxidative addition of nitrosonium ion to sulfur-bridged binuclear iron(II) and cobalt(II) complexes (1977) (11)
- Current research topics in bioinorganic chemistry (1973) (10)
- Water induces a structural conversion and accelerates the oxygenation of carboxylate-bridged non-heme diiron enzyme synthetic analogues. (2006) (10)
- Synthetic and Structural Studies of Titanium Aminotroponiminate Complexes. (1999) (10)
- Possible causes of upper mantle decoupling and ophiolite displacement (1984) (10)
- 2-Phenoxypyridyl dinucleating ligands for assembly of diiron(II) complexes: efficient reactivity with O(2) to form (mu-Oxo)diiron(III) units. (2009) (10)
- Heptakis(alkyl isocyanide)molybdenum(II) complexes (1973) (10)
- Stopped-flow Fourier transform infrared spectroscopy of nitromethane oxidation by the diiron(IV) intermediate of methane monooxygenase. (2003) (10)
- 8.13 – Nonheme Di-iron Enzymes (2003) (10)
- Reactivity of the Coordinated η2-Ketone in the Tropocoronand Complex [Hf(TC-3,5)(η2-OC(CH2Ph)2)]: N−C Coupling, C−C Coupling, and Insertion into the C−O Bond (1998) (10)
- X-ray Crystal Structure of a Monofunctional Platinum–DNA Adduct, cis-{Pt(NH3)2-(Pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex (2008) (10)
- Mechanistic studies of the oxidative N-dealkylation of a substrate tethered to carboxylate-bridged diiron(II) complexes, [Fe2(mu-O2CAr(Tol))2(O2CAr(Tol))2(N,N-Bn2en)2]. (2006) (10)
- SYNTHESIS AND REACTIVITY OF CATIONIC GROUP 4 TROPOCORONAND COMPLEXES (1998) (10)
- Toxicity of platinum(II) amino acid (N,O) complexes parallels their binding to DNA as measured in a new solid phase assay involving a fluorescent HMG1 protein construct readout (1999) (10)
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- In Color on the Front Cover. (1999) (0)
- Cumulative Index, Volumes 1-27 (1980) (0)
- KRISTALL- UND MOLEKULARSTRUKTUR VON BIS-(AETHYLTHIOXANTHATO)-MY-BIS-(AETHYLTHIOXANTHATO)-MY′-BIS-(AETHYLMERCAPTO)-DIEISEN(III) (1971) (0)
- 1 Dioxygen Activation in Soluble Methane Monooxygenase † (2011) (0)
- Aza- and Oxaphosphands, a New Class of Hard/Soft Binucleating Phosphine Macrocycles. (1987) (0)
- Modeling the active site of non-heme iron proteins: Synthesis and characterization of carboxylate-bridged diiron(II) complexes (1995) (0)
- Forward depositional modell ing of the Cretaceous post-rift deposits in the northern North Sea (2012) (0)
- Synthesis and magnetochemistry of a new decanuclear manganese complex. (1993) (0)
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Other Resources About Stephen J. Lippard
What Schools Are Affiliated With Stephen J. Lippard?
Stephen J. Lippard is affiliated with the following schools:
- University of Zurich
- University of Duisburg-Essen
- City University of Hong Kong
- University of California, San Diego
- NOVA University Lisbon
- Osaka University
- Columbia University
- Nara Women's University
- Yale University
- Haverford College
- Hebrew University of Jerusalem
- Stanford University
- Massachusetts Institute of Technology
- University of Florence
- University of North Carolina at Chapel Hill
