Stephen Malawista

Stephen Malawista's AcademicInfluence.com Rankings

Stephen Malawista

Philosophy

#6635

World Rank

#9700

Historical Rank

#1549

USA Rank

Logic

#3784

World Rank

#4993

Historical Rank

#732

USA Rank

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Philosophy

Why Is Stephen Malawista Influential?

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According to Wikipedia, Stephen Evan Malawista was an American medical researcher and Professor of medicine within the rheumatology department of Yale University. Malawista is credited as the co-discover of Lyme disease and led the research team which identified the disease.

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Stephen Malawista's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The spirochetal etiology of Lyme disease. (1983) (1505)
Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. (1977) (1181)
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo (2012) (685)
Erythema chronicum migrans and Lyme arthritis. The enlarging clinical spectrum. (1977) (613)
The early clinical manifestations of Lyme disease. (1983) (606)
Lyme carditis: cardiac abnormalities of Lyme disease. (1980) (513)
Neurologic Abnormalities of Lyme Disease (1979) (422)
Treatment of the early manifestations of Lyme disease. (1983) (374)
A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium. (1998) (307)
Erythema chronicum migrans and Lyme arthritis: epidemiologic evidence for a tick vector. (1978) (285)
Cases of Lyme disease in the United States: locations correlated with distribution of Ixodes dammini. (1979) (274)
Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin. (1983) (255)
Vinblastine and Griseofulvin Reversibly Disrupt the Living Mitotic Spindle (1968) (251)
The Inflammatory Reaction to Sodium Urate: Its Possible Relationship to the Genesis of Acute Gouty Arthritis (1962) (242)
Chronic Lyme arthritis. Clinical and immunogenetic differentiation from rheumatoid arthritis. (1979) (240)
Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution. (1991) (222)
Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1. (1987) (220)
Lyme disease: recommendations for diagnosis and treatment. (1991) (214)
Antibiotic therapy in Lyme disease. (1980) (212)
Lyme arthritis. Spirochetes found in synovial microangiopathic lesions. (1985) (212)
Successful parenteral penicillin therapy of established Lyme arthritis. (1985) (212)
Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease (1996) (211)
Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes. (1992) (191)
Detection of Borrelia burgdorferi DNA in museum specimens of Ixodes dammini ticks. (1990) (186)
Cytochalasin B reversibly inhibits phagocytosis: functional, metabolic, and ultrastructural effects in human blood leukocytes and rabbit alveolar macrophages. (1971) (184)
Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly (2008) (174)
The dissociation by colchicine of phagocytosis from increased oxygen consumption in human leukocytes. (1967) (159)
Chronic granulomatous disease in females. (1970) (145)
THE MOBILIZATION AND EXTRACELLULAR RELEASE OF GRANULAR ENZYMES FROM HUMAN LEUKOCYTES DURING PHAGOCYTOSIS (1972) (138)
Histamine release from rat peritoneal mast cells: inhibition by colchicine and potentiation by deuterium oxide. (1968) (136)
The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse macrophages. Destruction, survival, recovery. (1993) (132)
The clinical spectrum and treatment of Lyme disease. (1984) (129)
Defective polymorphonuclear-leukocyte function and chronic granulomatous disease in two female children. (1968) (129)
Colchicine: a common mechanism for its anti-inflammatory and anti-mitotic effects. (1968) (124)
Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly (2011) (123)
Human Polymorphonuclear Leukocytes: Demonstration of Microtubules and Effect of Colchicine (1967) (119)
Lyme arthritis: correlation of serum and cryoglobulin IgM with activity, and serum IgG with remission. (1979) (118)
ON THE ACTION OF COLCHICINE THE MELANOCYTE MODEL (1965) (117)
Target imbalance: disparity of Borrelia burgdorferi genetic material in synovial fluid from Lyme arthritis patients. (1994) (117)
Effects of colchicine on cyclic AMP levels in human leukocytes. (1977) (114)
Immune complexes and the evolution of Lyme arthritis. Dissemination and localization of abnormal C1q binding activity. (1979) (105)
Prenatal diagnosis of chronic granulomatous disease. (1979) (104)
Calprotectin, an Abundant Cytosolic Protein from Human Polymorphonuclear Leukocytes, Inhibits the Growth of Borrelia burgdorferi (2003) (97)
Treatment of rheumatoid arthritis by extracorporeal photochemotherapy. A pilot study. (1991) (91)
Fate of Borrelia burgdorferi DNA in tissues of infected mice after antibiotic treatment. (1994) (89)
Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes (PMN) in the presence of EDTA: PMN in close quarters require neither leukocyte integrins nor external divalent cations. (1997) (88)
Exploitation of Interleukin-8-Induced Neutrophil Chemotaxis by the Agent of Human Granulocytic Ehrlichiosis (2001) (84)
Tick Saliva Reduces Adherence and Area of Human Neutrophils (2004) (82)
Circulating immune complexes in Lyme arthritis. Detection by the 125I-C1q binding, C1q solid phase, and Raji cell assays. (1979) (79)
Inhibition of Borrelia burgdorferi-Tick Interactions In Vivo by Outer Surface Protein A Antibody1 (2001) (78)
Expression of differentiated functions in hepatoma cell hybrids: high frequency of induction of mouse albumin production in rat hepatoma-mouse lymphoblast hybrids. (1974) (77)
Recovery of Lyme disease spirochetes from patients. (1984) (77)
Anti-inflammatory effects of estradiol on human blood leukocytes. (1972) (75)
Human phagocytic cells in the early innate immune response to Borrelia burgdorferi. (2002) (73)
Erythema chronicum migrans and Lyme arthritis: cryoimmunoglobulins and clinical activity of skin and joints. (1977) (72)
Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks (2010) (70)
THE MELANOCYTE MODEL (1971) (69)
Mobilization and extracellular release of granular enzymes from human leukocytes during phagocytosis: inhibition by colchicine and cortisol but not by salicylate. (1973) (69)
Analysis of the PKC-γ-Related Immunocrossreactive Region of a Novel Leukocyte Protein γ-rp (1999) (69)
Recruitment of Macrophages and Polymorphonuclear Leukocytes in Lyme Carditis (2006) (69)
Detection of Borrelia burgdorferi DNA in museum specimens of Peromyscus leucopus. (1994) (69)
Anticardiolipin antibodies in Lyme disease. (1988) (69)
Cytochalasin B Reversibly Inhibits Melanin Granule Movement in Melanocytes (1971) (68)
Borrelia burgdorferi are susceptible to killing by a variety of human polymorphonuclear leukocyte components. (2002) (68)
Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes from a patient with leukocyte adhesion deficiency-1: normal displacement in close quarters via chimneying. (2000) (63)
Phosphorylation of the oxidase-related 48K phosphoprotein family in the unusual autosomal cytochrome-negative and X-linked cytochrome-positive types of chronic granulomatous disease. (1988) (62)
Entry of Borrelia burgdorferi into macrophages is end-on and leads to degradation in lysosomes (1996) (62)
Crystal-induced endogenous pyrogen production. A further look at gouty inflammation. (1985) (60)
Colchicine, vinblastine and griseofulvin. Pharmacological studies with human leukocytes. (1971) (60)
The action of colchicine in acute gouty arthritis. (1975) (58)
Mechanism of action of colchicine (1975) (57)
MICROTUBULES AND THE MOBILIZATION OF LYSOSOMES IN PHAGOCYTIZING HUMAN LEUKOCYTES * (1975) (56)
Elevated levels of collagenase and prostaglandin e2 from synovium associated with chronic lyme arthritis (1980) (54)
A simple rapid micromethod for detecting chronic granulomatous disease of childhood. (1970) (52)
Fc- and non-Fc-mediated phagocytosis of Borrelia burgdorferi by macrophages. (1994) (52)
Superoxide anion production during Anaplasma phagocytophila infection. (2002) (51)
THE EFFECT OF PRETREATMENT WITH COLCHICINE ON THE INFLAMMATORY RESPONSE TO MICROCRYSTALLINE URATE: A MODEL FOR GOUTY INFLAMMATION. (1965) (51)
Vinblastine: colchicine-like effects on human blood leukocytes during phagocytosis. (1971) (48)
The fever of gout: urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes. (1983) (47)
Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging (2014) (45)
Protein kinase C isoforms in human neutrophil cytoplasts (1992) (45)
Cryopreservable neutrophil surrogates. Stored cytoplasts from human polymorphonuclear leukocytes retain chemotactic, phagocytic, and microbicidal function. (1989) (43)
Recruitment of the cross-linked opsonic receptor CD32A (FcgammaRIIA) to high-density detergent-resistant membrane domains in human neutrophils. (2004) (43)
Tonic inhibition of chemotaxis in human plasma (2008) (40)
Studies on ochronosis. II. Studies on benzoquinoneacetic acid, a probale intermediate in the connective tissue pigmentation of alcaptonuria. (1962) (39)
The action of colchicine in acute gout. (1965) (37)
Griseofulvin: association with tubulin and inhibition of in vitro microtubule assembly. (1982) (37)
The nitroblue tetrazolium reaction in human granulocytes adherent to a surface. (1972) (34)
Circulating Borrelia burgdorferi in patients with acute Lyme disease: results of blood cultures and serum DNA analysis. (1993) (34)
The pathogenesis of arthritis in Lyme disease: humoral immune responses and the role of intra-articular immune complexes. (1984) (33)
The interaction of colchicine with hormone-sensitive adenylate cyclase in human leukocytes. (1979) (33)
Heat shock in human neutrophils: Superoxide generation is inhibited by a mechanism distinct from heat‐denaturation of NADPH oxidase and is protected by heat shock proteins in thermotolerant cells (1993) (33)
Cytoplasts made from human blood polymorphonuclear leukocytes with or without heat: preservation of both motile function and respiratory burst oxidase activity. (1987) (32)
Inflammatory Gout: Observations over a Half‐Century (2011) (29)
Elevated levels of collagenase and prostaglandin E2 from synovium associated with erosion of cartilage and bone in a patient with chronic Lyme arthritis. (1980) (28)
Photopheresis for Rheumatoid Arthritis a (1991) (24)
Opinion:: Resolution of Lyme Arthritis, Acute or Prolonged: A New Look (2000) (24)
Cytochalasin B Inhibits Lymphotoxin Production by Antigen-Stimulated Lymphocytes (1972) (23)
Lyme disease: infectious in origin, rheumatic in expression. (1986) (22)
Clinical manifestations of Lyme disease. (1986) (22)
Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component. (1992) (22)
Failure of multitarget detection of Borrelia burgdorferi-associated DNA sequences in synovial fluids of patients with juvenile rheumatoid arthritis: a cautionary note. (1992) (21)
Clocking the Lyme Spirochete (2008) (21)
Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection (2012) (20)
Lyme arthritis: a new clinical entity. (1978) (19)
Treatment of Lyme disease. (1987) (18)
MICROTUBULES AND THE MOVEMENT OF MELANIN GRANULES IN FROG DERMAL MELANOCYTES * (1975) (18)
Phagocytosis by human blood leucocytes during suppression of glycolysis. (1969) (18)
Stimulated cytokineplasts from human polymorphonuclear leukocytes mobilize calcium and polymerize actin. Cytoplasts made in cytochalasin B retain a defect in actin polymerization. (1986) (17)
Murine Lyme disease: no evidence for active immune down-regulation in resolving or subclinical infection. (2001) (17)
Acrodermatitis chronica atrophicans in the United States: clinical and histopathologic features of six cases. (1994) (16)
Functional integrity of cytokineplasts: specific chemotactic and capping responses. (1985) (16)
Phagocytosis by human blood leukocytes measured by the uptake of 131I-labeled human serum albumin: inhibitory and stimulatory effects of cytochalasin B. (1973) (16)
Cytoplasts generate oxidants but require added neutrophil granule constituents for fungicidal activity against Candida albicans hyphae. (1995) (15)
Lyme disease: a unique human model for an infectious etiology of rheumatic disease. (1984) (14)
Chemotaxis by human neutrophils and their cytokineplasts treated with inhibitors of nitric oxide synthase: no suppression of orientation or trajectory (1997) (14)
Monosodium L-glutamate--inhibition of glucose uptake in brain as a basis for toxicity. (1971) (14)
Lumicolchicine: lack of antiinflammatory effect. (1972) (13)
Local and Systemic Complications of Rheumatoid Arthritis (1969) (13)
Human Neutrophil Calprotectin Reduces the Susceptibility of Borrelia burgdorferi to Penicillin (2006) (13)
Colchicine: anti-inflammatory effect of low doses in a sensitive bacterial system. (1968) (13)
An ospA frame shift, identified from DNA in Lyme arthritis synovial fluid, results in an outer surface protein A that does not bind protective antibodies. (1995) (13)
Cytochalasin B Reversibly Inhibits Phagocytosis by Human Blood Leukocytes (1971) (13)
A circulating anticoagulant directed against factor XIa in systemic lupus erythematosus. (1979) (13)
SIMPLE SCREENING TEST ON CLOTTED BLOOD FOR CHRONIC GRANULOMATOUS DISEASE OF CHILDHOOD (1978) (12)
Borrelia burgdorferi and the macrophage: routine annihilation but occasional haven? (1994) (12)
Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible and irreversible inhibitors of nitric oxide synthase (1996) (12)
Chronic granulomatous disease and glutathione peroxidase deficiency, revisited. (1994) (12)
Pathogenesis of Lyme disease (2004) (12)
ON THE ACTION OF COLCHICINE (1965) (12)
Phagocytic capacity of cytokineplasts from human blood polymorphonuclear leukocytes. (1986) (11)
Cryopreserved Cytoplasts From Human Polymorphonuclear Leukocytes (Cytokineplasts) Are Chemotactic at Speeds Comparable to Those of Fresh Intact Cells (1991) (11)
Vaccinia gangrenosa in chronic lymphatic leukemia. Report of a case with recovery following the use of vaccinia immune globulin. (1962) (10)
Colchicine, crystals, and neutrophil tyrosine phosphorylation. (1993) (10)
Evaluation of an Epidemiological Method (1959) (10)
Geographic clustering of an outer surface protein A mutant of Borrelia burgdorferi. Possible implications of multiple variants for Lyme disease persistence. (2000) (10)
Cryopreservable neutrophil surrogates: granule-poor, motile cytoplasts from polymorphonuclear leukocytes home to inflammatory lesions in vivo. (2006) (10)
The phlogistic potential of urate in solution (1979) (9)
Dissociation of the mitotic spindle in oocytes exposed to grisofulvin and vinblastine. (1976) (9)
Chemotactic activity of human blood leukocytes in plasma treated with EDTA: chemoattraction of neutrophils about monocytes is mediated by the generation of NAP‐2 (2002) (8)
Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults (2010) (8)
Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks (2011) (8)
Historical perspective of Lyme disease. (1986) (7)
Anaplasma phagocytophiluminduces actin phosphorylation to selectively regulate gene transcription inIxodes scapularisticks (2010) (7)
MISOPROSTOL STIMULATES cAMP GENERATION IN HUMAN LEUKOCYTES: SYNERGY WITH COLCHICINE SUGGESTS A NEW POTENTIAL FOR ESTABLISHED DRUGS (1995) (6)
The phlogistic potential of urate in solution: studies of the phagocytic process in human leukocytes. (1979) (6)
Inhibition of lymphocyte triggering by cytochalasin B. (1972) (6)
Erythema chronicum migrans and Lyme arthritis: related problems recently recognized in Connecticut. (1978) (6)
Functional Competence of Peritoneal Macrophages in Murine Lyme Borreliosis (2004) (5)
Misoprostol stimulates leukocyte cyclic adenosine 3',5' monophosphate production and synergizes with colchicine: novel combination of established drugs may boost anti-inflammatory potential. (1994) (4)
Cytokineplasts from human blood polymorphonuclear leukocytes (1985) (4)
The effect of folic acid on tyrosine metabolism in guinea pigs. (1962) (4)
Treatment of Lyme disease. (1987) (3)
The American College of Rheumatology. Evolution through planning. (1993) (3)
Chloroquine: protective and destructive effects on injured rabbit cartilage in vivo. (1973) (3)
The treatment of disseminated vasculitis with methotrexate (1976) (3)
Lyme disease (1989) (3)
Biochemistry of the Phagocytic Process (1972) (3)
Eighteenth rheumatism review. Review of American and English literature for the years 1965 and 1966. (1968) (2)
Chronic Lyme Arthritis (2020) (2)
Phagocytosis by alveolar macrophages: pharmacologic features. (1973) (2)
Glucose oxidation in alveolar macrophages: pharmacologic features. (1974) (2)
Cytokineplasts and U-cytoplasts from human polymorphonuclear leukocytes: role of granule-poor motile fragments in the analysis of cell physiology. (1993) (2)
Treatment of asymptomatic, retrospectively diagnosed, Lyme disease: comment on the report by Christian. (1993) (1)
Parvovirus arthritis mistaken for Lyme arthritis. (1992) (1)
Multicenter efficacy trial of a prophylactic recombinant Borrelia burgdorferi (Bb) Outer Surface Protein A (OspA) vaccine for Lyme Disease (LD) (1997) (1)
Phagocytic Function of Human Blood Polymorphonuclear Leukocytes in the Presence of Carrageenan, a Potential Vaginal Microbicide (2007) (1)
Discussion: Clinical Features (Part Two) (1984) (1)
THE MELANOCYTE MODEL Colchicine-like Effects of Other Antimitotic Agents (2003) (1)
Clinical judgment in Lyme disease. (1990) (1)
An Apparently Novel Protein of Human Leukocytes, Reactive with an Antibody to Protein Kinase C-γ, Is Rapidly Modified upon Cell Activation: Initial Characterization in Neutrophils and Their Cytoplasts (1998) (1)
Erythema Chronicum Migrans and Lyme Arthritis (2020) (0)
Vaccinia Gangrenosa in Chronic Lymphatic Leukemia (2016) (0)
Double-decker chemotaxis: no evidence for photonic stimulation of directed locomotion by human blood polymorphonuclear leukocytes. (2002) (0)
Lyme disease ( needle biopsy ) Reiter ' s disease Rheumatoid arthritis Chronic synovitis of unknown type Trauma Hemarthrosis due to hemophilia Acute suppurative arthritis Psoriatic arthritis Pseudogout (0)
Plunder of Human Blood Leukocytes Containing Ingested Material, by Other Leukocytes: Where Is the Fusagen That Allows Preservation of Membrane Integrity and Motile Function? (2013) (0)
Histoplasmin, tuberculin and coccidioidin skin sensitivity in Liberian aborigines. (1959) (0)
Histoplasmin, tuberculin and coccidioidin sensitivity in Libeiian aborigines. (1959) (0)
Analysis of the PKC-gamma-related immunocrossreactive region of a novel leukocyte protein gamma-rp. (1999) (0)
The 1969 annual meeting of the American Rheumatism Association. (1969) (0)
On acute gouty arthritis (2012) (0)
Human Neutrophils Tick Saliva Reduces Adherence and Area of (2004) (0)
Antimicrobial capacity of cytokineplasts: how many granules are enough? Commentary on Phagocytic capacity of cytokineplasts from human blood polymorphonuclear leukocytes. Reply (1986) (0)
Marrow aplasia induced by colchicine. A case report. Discussion. (1978) (0)
Lyme disease: current problems in diagnosis, therapy, and prevention. (1993) (0)
Discussion: Causative Agent and Host Response (Part Two) (1984) (0)

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