Stephen N. Thibodeau
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Philosophy Biology
Stephen N. Thibodeau's Degrees
- Doctorate Medicine Johns Hopkins University
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(Suggest an Edit or Addition)Stephen N. Thibodeau's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. (1998) (4146)
- Microsatellite instability in cancer of the proximal colon. (1993) (3190)
- APC mutations occur early during colorectal tumorigenesis (1992) (2025)
- Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. (2003) (2023)
- CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer (2006) (1849)
- Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. (2010) (1318)
- Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. (1996) (1255)
- REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants. (2016) (1110)
- Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. (1998) (878)
- Characterization of human plasma-derived exosomal RNAs by deep sequencing (2013) (853)
- Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. (1995) (806)
- Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. (2002) (805)
- Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC (1994) (632)
- Evidence for a prostate cancer susceptibility locus on the X chromosome. (1998) (620)
- CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer (2013) (574)
- Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. (2005) (571)
- Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. (1998) (569)
- Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array (2012) (550)
- Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel. (2000) (550)
- Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. (1998) (542)
- The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations. (2008) (516)
- Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (509)
- Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. (2015) (507)
- Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. (1996) (499)
- Length of uninterrupted CGG repeats determines instability in the FMR1 gene (1994) (478)
- Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. (2012) (457)
- Identification of Lynch syndrome among patients with colorectal cancer. (2012) (456)
- EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome (2009) (442)
- Identification of seven new prostate cancer susceptibility loci through a genome-wide association study (2009) (428)
- Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database (2013) (419)
- A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer (2014) (416)
- DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy. (2011) (399)
- Clinical features of 5,628 primary lung cancer patients: experience at Mayo Clinic from 1997 to 2003. (2005) (392)
- Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. (1999) (382)
- Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling (2000) (375)
- Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer (2007) (373)
- The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. (2001) (357)
- BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing (2004) (349)
- Risks of Lynch syndrome cancers for MSH6 mutation carriers. (2010) (346)
- Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer (2008) (337)
- A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer (2009) (337)
- Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study. (2007) (321)
- Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states (2009) (315)
- Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. (2013) (300)
- Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. (2012) (300)
- Mutations in CHEK2 associated with prostate cancer risk. (2003) (299)
- Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study (2011) (295)
- BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. (2003) (295)
- Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes. (2015) (285)
- Apolipoprotein E: risk factor for Alzheimer disease. (1994) (283)
- Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. (2012) (283)
- Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database (2019) (280)
- Discovery of common and rare genetic risk variants for colorectal cancer (2018) (279)
- Cigarette smoking and colorectal cancer risk by molecularly defined subtypes. (2010) (276)
- Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease (1998) (273)
- Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling (vol 26, pg 146, 2000) (2000) (269)
- Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations. (1998) (262)
- Genotype‐phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium (1995) (259)
- Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer (2016) (253)
- Evidence for a prostate cancer-susceptibility locus on chromosome 20. (2000) (249)
- MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. (2004) (245)
- Development of a Fluorescent Multiplex Assay for Detection of MSI-High Tumors (2004) (243)
- Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. (1996) (242)
- Evidence for autosomal dominant inheritance of prostate cancer. (1998) (233)
- Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy. (2013) (232)
- Prognostic Significance of Defective Mismatch Repair and BRAF V600E in Patients with Colon Cancer (2008) (231)
- Analysis of a CGG sequence at the FMR-1 locus in fragile X families and in the general population. (1993) (228)
- A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. (2005) (220)
- Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19 (2018) (219)
- Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk (2014) (218)
- Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741. (2010) (216)
- Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients. (2006) (215)
- Substantial unexplained variation in cancer risks for MLH1 and MSH2 mutation carriers (2012) (210)
- High functioning fragile X males: demonstration of an unmethylated fully expanded FMR-1 mutation associated with protein expression. (1994) (210)
- Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening (2008) (201)
- Microsatellite instability in Muir-Torre syndrome. (1994) (191)
- Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease (1998) (187)
- HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG) (2012) (186)
- Allelic imbalance and microsatellite instability in prostatic adenocarcinoma. (1996) (186)
- The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history. (2011) (185)
- Case-control study of overweight, obesity, and colorectal cancer risk, overall and by tumor microsatellite instability status. (2010) (183)
- The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas (2016) (182)
- The Mayo Clinic Biobank: a building block for individualized medicine. (2013) (175)
- PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS (2016) (174)
- Multiple Novel Prostate Cancer Predisposition Loci Confirmed by an International Study: The PRACTICAL Consortium (2008) (169)
- Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (163)
- A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics. (2005) (161)
- Sequence analysis of the fragile X trinucleotide repeat: implications for the origin of the fragile X mutation. (1994) (158)
- miRNA Expression in Colon Polyps Provides Evidence for a Multihit Model of Colon Cancer (2011) (150)
- Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility Loci. (2004) (149)
- Origin of microsatellite instability in gastric cancer. (1999) (149)
- BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins. (2008) (149)
- Gene networks and microRNAs implicated in aggressive prostate cancer. (2009) (148)
- Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas. (1991) (147)
- The stool DNA test is more accurate than the plasma septin 9 test in detecting colorectal neoplasia. (2012) (146)
- Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. (2016) (146)
- Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147. (2014) (142)
- Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk. (2008) (140)
- Estrogen plus progestin use, microsatellite instability, and the risk of colorectal cancer in women. (2007) (140)
- Reduced COX-2 protein in colorectal cancer with defective mismatch repair. (1998) (138)
- Expression of p53 and 17p allelic loss in colorectal carcinoma. (1992) (137)
- Nonparametric tests of association of multiple genes with human disease. (2005) (135)
- Genetic heterogeneity in Peutz‐Jeghers syndrome (2000) (134)
- Synthesis of renin by tubulocystic epithelium in autosomal-dominant polycystic kidney disease. (1992) (133)
- A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. (2013) (131)
- Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression. (1995) (130)
- Clonal studies in the myelodysplastic syndrome using X-linked restriction fragment length polymorphisms. (1990) (130)
- The application of fluorescent in situ hybridization to detect Mbcr/abl fusion in variant Ph chromosomes in CML and ALL. (1993) (130)
- KRAS Codon 12 and 13 Mutations in Relation to Disease-Free Survival in BRAF–Wild-Type Stage III Colon Cancers from an Adjuvant Chemotherapy Trial (N0147 Alliance) (2014) (129)
- Mismatch Repair Gene PMS2 (2004) (129)
- Cancer Risks for PMS2-Associated Lynch Syndrome. (2018) (128)
- Associations between Smoking, Alcohol Consumption, and Colorectal Cancer, Overall and by Tumor Microsatellite Instability Status (2009) (125)
- Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry. (2011) (121)
- Diagnosis of alpha-1-antitrypsin deficiency: An algorithm of quantification, genotyping, and phenotyping. (2006) (121)
- Evaluation of Genetic Variations in the Androgen and Estrogen Metabolic Pathways as Risk Factors for Sporadic and Familial Prostate Cancer (2007) (120)
- MGMT Immunohistochemical Expression and Promoter Methylation in Human Glioblastoma (2007) (118)
- Analysis of the RNASEL gene in familial and sporadic prostate cancer. (2002) (117)
- Use of Microsatellite Instability and Immunohistochemistry Testing for the Identification of Individuals at Risk for Lynch Syndrome (2004) (116)
- Two common chromosome 8q24 variants are associated with increased risk for prostate cancer. (2007) (115)
- A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. (2015) (113)
- Telomere Length Varies By DNA Extraction Method: Implications for Epidemiologic Research (2013) (111)
- Confirmation of deficient mismatch repair (dMMR) as a predictive marker for lack of benefit from 5-FU based chemotherapy in stage II and III colon cancer (CC): A pooled molecular reanalysis of randomized chemotherapy trials (2008) (109)
- Preclinical memory decline in cognitively normal apolipoprotein E–ε4 homozygotes (1999) (108)
- Human SULT1A1 gene: copy number differences and functional implications. (2007) (107)
- Adjuvant mFOLFOX6 with or without cetuxiumab (Cmab) in KRAS wild-type (WT) patients (pts) with resected stage III colon cancer (CC): Results from NCCTG Intergroup Phase III Trial N0147. (2010) (105)
- The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) – Results of an international collaborative study (2001) (105)
- T-cell receptor gene rearrangement analysis: cutaneous T cell lymphoma, peripheral T cell lymphoma, and premalignant and benign cutaneous lymphoproliferative disorders. (1991) (104)
- A 30 kb deletion within the elastin gene results in familial supravalvular aortic stenosis. (1995) (103)
- Novel Common Genetic Susceptibility Loci for Colorectal Cancer (2018) (102)
- Neurofibromatosis type 1 gene as a mutational target in a mismatch repair-deficient cell type (2003) (102)
- Caution on pedigree haplotype inference with software that assumes linkage equilibrium. (2002) (102)
- The premortem recognition of systemic senile amyloidosis with cardiac involvement. (1996) (100)
- Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression (2013) (100)
- Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age (2003) (100)
- Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. (2007) (100)
- Representative cDNA libraries and their utility in gene expression profiling. (1999) (99)
- Identical precursors for serum transferrin and egg white conalbumin. (1978) (98)
- Role of HPC2/ELAC2 in hereditary prostate cancer. (2001) (97)
- Chromosomal Instability in Microsatellite-Unstable and Stable Colon Cancer (2006) (97)
- Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. (2011) (95)
- Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer. (2011) (94)
- Tumor Budding in Colorectal Carcinoma: Confirmation of Prognostic Significance and Histologic Cutoff in a Population-based Cohort (2015) (94)
- HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. (2000) (93)
- Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH (2016) (92)
- HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression (2011) (92)
- Lynch Syndrome–Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry (2010) (92)
- Mycosis fungoides in children and adolescents. (1990) (92)
- Linkage analyses at the chromosome 1 loci 1q24-25 (HPC1), 1q42.2-43 (PCAP), and 1p36 (CAPB) in families with hereditary prostate cancer. (2000) (92)
- Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants. (2015) (91)
- Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage (2013) (91)
- Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients. (2015) (89)
- Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer (2014) (89)
- Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: Associations with family history and histopathology (2000) (88)
- Evidence for a Prostate Cancer Susceptibility Locus on the X Chromosome (1999) (88)
- Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. (2016) (87)
- Alpha1-antitrypsin deficiency allele carriers among lung cancer patients. (1999) (86)
- Familial amyloidosis: a study of 52 North American-born patients examined during a 30-year period. (1992) (85)
- A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry (2013) (85)
- Aspirin, Ibuprofen, and the Risk of Colorectal Cancer in Lynch Syndrome. (2015) (85)
- Mitochondrial Genetic Polymorphisms and Pancreatic Cancer Risk (2007) (83)
- The gene for HMSN2C maps to 12q23-24 (2003) (83)
- Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (83)
- Third-party-mediated graft rejection and graft-versus-host disease after T-cell-depleted bone marrow transplantation, as demonstrated by hypervariable DNA probes and HLA-DR polymorphism. (1989) (82)
- Leukocyte DNA Methylation Signature Differentiates Pancreatic Cancer Patients from Healthy Controls (2011) (82)
- Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data (2013) (81)
- Genome-Wide Transcriptional Profiling Reveals MicroRNA-Correlated Genes and Biological Processes in Human Lymphoblastoid Cell Lines (2009) (79)
- Isolated supravalvular aortic stenosis: functional haploinsufficiency of the elastin gene as a result of nonsense-mediated decay (2000) (79)
- Genomic instability in neoplasia. (1995) (79)
- Rothmund‐Thomson syndrome in siblings: evidence for acquired in vivo mosaicism (1996) (78)
- The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium (2015) (78)
- Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers (2018) (78)
- Iron overload in cirrhosis—HFE genotypes and outcome after liver transplantation (2000) (78)
- Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q. (2003) (78)
- Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer. (2019) (78)
- Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers: A Secondary Analysis of 2 Randomized Clinical Trials (2017) (77)
- Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis (2020) (76)
- Microsatellite Instability Accounts for Tumor Site-Related Differences in Clinicopathologic Variables and Prognosis in Human Colon Cancers (2006) (75)
- Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study (2008) (75)
- Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk. (2020) (74)
- Prognostic impact of deficient mismatch repair (dMMR) in 7,803 stage II/III colon cancer (CC) patients (pts): A pooled individual pt data analysis of 17 adjuvant trials in the ACCENT database. (2014) (73)
- BRCA1 and BRCA2 have a limited role in familial prostate cancer. (2000) (71)
- Risk of microsatellite-unstable colorectal cancer is associated jointly with smoking and nonsteroidal anti-inflammatory drug use. (2006) (71)
- Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome. (2015) (71)
- Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans (2015) (71)
- Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry (2012) (70)
- No association of germline alteration of MSR1 with prostate cancer risk (2003) (70)
- Mutation‐specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas (2013) (69)
- Cystic fibrosis and the phenotypic expression of autosomal dominant polycystic kidney disease. (1998) (68)
- The Role of Defective Mismatch Repair in Small Bowel Adenocarcinoma in Celiac Disease (2004) (67)
- Different mechanisms underlie DNA instability in Huntington disease and colorectal cancer. (1997) (67)
- The fragile X premutation in carriers and its effect on mutation size in offspring. (1995) (67)
- Shared heritability and functional enrichment across six solid cancers (2018) (67)
- Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers. (2000) (66)
- Prevalence of alterations in DNA mismatch repair genes in patients with young-onset colorectal cancer. (2011) (65)
- Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci (2015) (65)
- Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk (2015) (65)
- Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance) (2015) (63)
- APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests. (2013) (63)
- Autosomal dominant supravalvular aortic stenosis: localization to chromosome 7. (1993) (63)
- Isolated Loss of PMS2 Expression in Colorectal Cancers: Frequency, Patient Age, and Familial Aggregation (2005) (62)
- Lynch Syndrome-Associated Extracolonic Tumors Are Rare in Two Extended Families With the Same EPCAM Deletion (2011) (62)
- Methylation Markers for Small Cell Lung Cancer in Peripheral Blood Leukocyte DNA (2010) (62)
- cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue (2012) (62)
- Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set (2015) (61)
- Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women’s Health Study (2016) (61)
- pharmacogenetic analysis of systemic toxicity and response after 5-fluorouracil (5fu)/cpt-11, 5fu/oxaliplatin (oxal), or Cpt-11/oxal therapy for advanced colorectal cancer (crc): Results from an intergroup trial : 1013 (2003) (60)
- Identification of transthyretin variants by sequential proteomic and genomic analysis. (2004) (59)
- Polymorphisms in Mitochondrial Genes and Prostate Cancer Risk (2008) (59)
- Mutations in the RET protooncogene in sporadic pheochromocytomas. (1995) (59)
- Current status of adjuvant chemotherapy for colorectal cancer: Can molecular markers play a role in predicting prognosis? (1992) (58)
- PMS2 monoallelic mutation carriers: the known unknown (2015) (58)
- Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. (2015) (57)
- Adjuvant mFOLFOX6 plus or minus cetuximab (Cmab) in patients (pts) with KRAS mutant (m) resected stage III colon cancer (CC): NCCTG Intergroup Phase III Trial N0147 (2010) (56)
- Genome linkage screen for prostate cancer susceptibility loci: Results from the Mayo Clinic familial prostate cancer study (2003) (56)
- Prediction of individual genetic risk to prostate cancer using a polygenic score (2015) (56)
- Heterogenous MSH6 Loss Is a Result of Microsatellite Instability Within MSH6 and Occurs in Sporadic and Hereditary Colorectal and Endometrial Carcinomas (2015) (56)
- Sequential expression of miR‐182 and miR‐503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma (2014) (56)
- Predictive Value of APOE Genotyping in Incipient Alzheimer's Diseases a (1996) (55)
- Blood lipids and prostate cancer: a Mendelian randomization analysis (2016) (55)
- Integrated analysis of genome‐wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype‐negative colon cancer (2013) (55)
- Current status of adjuvant chemotherapy for colorectal cancer. Can molecular markers play a role in predicting prognosis? (1992) (54)
- High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing (2018) (54)
- Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer (2009) (54)
- Preclinical memory decline in cognitively normal apolipoprotein E-epsilon4 homozygotes. (1999) (54)
- A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer. (2015) (54)
- Associations between colorectal cancer molecular markers and pathways with clinicopathologic features in older women. (2013) (53)
- Characterization of hMLH1 and hMSH2 gene dosage alterations in Lynch syndrome patients. (2005) (53)
- Supravalvular aortic stenosis: a splice site mutation within the elastin gene results in reduced expression of two aberrantly spliced transcripts (1999) (53)
- Comparison of the clinical prediction model PREMM1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer (2012) (52)
- Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer. (2005) (52)
- Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation (2016) (52)
- Microsatellite instability in hereditary and sporadic breast cancers (2003) (51)
- Absence of mutations in DNA mismatch repair genes in sporadic endometrial tumors with microsatellite instability. (1996) (51)
- Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene. (1994) (50)
- Mendelian randomization study of height and risk of colorectal cancer. (2015) (50)
- Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes (2011) (49)
- High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry (2014) (49)
- Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers. (2008) (49)
- Mutations in the Human naked cuticle Homolog NKD1 Found in Colorectal Cancer Alter Wnt/Dvl/β-Catenin Signaling (2009) (49)
- Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women (2016) (49)
- The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. (2008) (48)
- Role of the Nijmegen Breakage Syndrome 1 Gene in Familial and Sporadic Prostate Cancer (2006) (48)
- Thymidylate Synthase Expression in Colon Carcinomas with Microsatellite Instability (2006) (47)
- Mapping of DNA markers close to the fragile site on the human X chromosome at Xq27.3. (1987) (47)
- The HOXB13 G84E Mutation Is Associated with an Increased Risk for Prostate Cancer and Other Malignancies (2015) (47)
- Molecular remission occurring after donor leukocyte infusions for the treatment of relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation. (1992) (47)
- A genetic review of complete and partial hydatidiform moles and nonmolar triploidy. (1992) (47)
- Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases (2015) (46)
- Genetic mapping of new DNA probes at Xq27 defines a strategy for DNA studies in the fragile X syndrome. (1991) (46)
- Tumor necrosis factor-α allelic frequency and chromosome 6 allelic imbalance in patients with colorectal cancer (1996) (46)
- Analysis of the prostate cancer-susceptibility locus HPC20 in 172 families affected by prostate cancer. (2001) (45)
- Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype (2015) (45)
- Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer. (2017) (44)
- Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts (2017) (44)
- Ethical Considerations Related to Return of Results from Genomic Medicine Projects: The eMERGE Network (Phase III) Experience (2018) (43)
- Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer (2014) (43)
- Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women (2011) (43)
- Functional and Clinical Significance of Variants Localized to 8q24 in Colon Cancer (2009) (42)
- Genotype prediction in the fragile X syndrome. (1991) (42)
- Determining the frequency of de novo germline mutations in DNA mismatch repair genes (2011) (42)
- Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing (2013) (42)
- Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer. (2016) (41)
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- Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives (2014) (41)
- H63D is an haemochromatosis associated allele (1998) (40)
- Proapoptotic Bad and Bid Protein Expression Predict Survival in Stages II and III Colon Cancers (2008) (40)
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- Cigarette Smoking and Colorectal Cancer Risk by KRAS Mutation Status Among Older Women (2012) (40)
- Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer (2010) (40)
- A Novel Mutation in KVLQT1 Is the Molecular Basis of Inherited Long QT Syndrome in a Near-Drowning Patient's Family (1998) (40)
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- Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort (2016) (36)
- Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort (2016) (36)
- Higher Frequency of Diploidy in Young-Onset Microsatellite-Stable Colorectal Cancer (2007) (36)
- Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers (2016) (35)
- Apolipoprotein E allele in Chamorros with amyotrophic lateral sclerosis/parkinsonism-dementia complex (1994) (35)
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- Microsatellite Instability in Keratoacanthoma (1995) (34)
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- Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes (2017) (31)
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- Alterations in cell proliferation and apoptosis in colon cancers with microsatellite instability (2007) (30)
- Genome-Wide Association Study of Prostate Cancer–Specific Survival (2015) (30)
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- Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22 (2012) (28)
- The genomic organization of human dystrobrevin (1997) (27)
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- Postmenopausal Hormone Therapy and Colorectal Cancer Risk in Relation to Somatic KRAS Mutation Status among Older Women (2012) (27)
- The Association of Tumor Microsatellite Instability Phenotype with Family History of Colorectal Cancer (2009) (27)
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- Assessing the role of insulin‐like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels (2016) (26)
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- An intronic region within the human factor VIII gene is duplicated within Xq28 and is homologous to the polymorphic locus DXS115 (767). (1989) (21)
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- Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus. (2010) (21)
- Model‐based prediction of defective DNA mismatch repair using clinicopathological variables in sporadic colon cancer patients (2010) (21)
- Alpha 1-Antitrypsin Deficiency Carriers , Tobacco Smoke , Chronic Obstructive Pulmonary Disease , and Lung Cancer Risk (2008) (21)
- Body Mass Index in Early Adulthood and Endometrial Cancer Risk for Mismatch Repair Gene Mutation Carriers (2011) (21)
- Prevalence and clinical significance of HFE gene mutations in patients with iron overload. (2000) (20)
- Luteinizing hormone β polymorphism and risk of familial and sporadic prostate cancer (2003) (20)
- eRNA: a graphic user interface-based tool optimized for large data analysis from high-throughput RNA sequencing (2014) (20)
- Rapid, nonradioactive screening for mutations in exons 10, 11, and 16 of the RET protooncogene associated with inherited medullary thyroid carcinoma. (1997) (20)
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- Germline PKHD1 mutations are protective against colorectal cancer (2011) (19)
- Developing a Process for Returning Medically Actionable Genomic Variants to Latino Patients in a Federally Qualified Health Center (2018) (19)
- Altered DNA mismatch repair expression in synchronous and metachronous colorectal cancers. (2008) (18)
- Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk (2020) (18)
- Mutational landscape of candidate genes in familial prostate cancer (2014) (18)
- Polymorphisms in the 5α reductase type 2 gene and urologic measures of BPH (2005) (18)
- Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (18)
- Alcohol Intake and Colorectal Cancer Risk by Molecularly Defined Subtypes in a Prospective Study of Older Women (2011) (18)
- Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report (2020) (18)
- An American founder mutation in MLH1 (2012) (18)
- Frequency of Defective DNA Mismatch Repair in Colorectal Cancer among the Alaska Native People (2007) (17)
- The Sangre Por Salud Biobank: Facilitating Genetic Research in an Underrepresented Latino Community (2016) (17)
- Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations (2018) (17)
- Differential expression and allelotyping of the p73 gene in neuroblastoma. (2000) (17)
- Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis (2016) (17)
- A search for germline APC mutations in early onset colorectal cancer or familial colorectal cancer with normal DNA mismatch repair (2001) (17)
- De novo 16p deletion: ATR-16 syndrome. (1997) (17)
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- Screening the dystrophin gene suggests a high rate of polymorphism in general but no exonic deletions in schizophrenics. (1994) (16)
- Premutations in the FMR1 Gene Are Uncommon in Men Undergoing Genetic Testing for Spinocerebellar Ataxia (2008) (16)
- COTRANSLATIONAL SEQUESTRATION OF EGG WHITE PROTEINS AND PLACENTAL LACTOGEN INSIDE MEMBRANE VESICLES * (1980) (16)
- Altered Expression of hMSH 2 and hMLH 1 in Tumors with Microsatellite Instability and Genetic Alterations in Mismatch Repair Genes 1 (2006) (15)
- DNA mismatch repair genes hMLH1, hMSH2, and hMSH6 are not inactivated in bronchioloalveolar carcinomas of the lung (2001) (15)
- Colorectal cancer and self-reported tooth agenesis (2014) (15)
- Detecting genomic clustering of risk variants from sequence data: cases versus controls (2013) (15)
- Returning Genomic Results in a Federally Qualified Health Center: The intersection of precision medicine and social determinants of health. (2020) (15)
- Associations between Cigarette Smoking, Hormone Therapy, and Folate Intake with Incident Colorectal Cancer by TP53 Protein Expression Level in a Population-Based Cohort of Older Women (2013) (15)
- Familial medullary thyroid cancer and prominent corneal nerves: clinical and genetic analysis. (1995) (15)
- Hb Tak confirmed by DNA analysis: not expressed as thalassemia in a Hb Tak/Hb E compound heterozygote. (1998) (15)
- Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database (2019) (15)
- Human SULT 1 A 1 gene : copy number differences and functional implications (2007) (14)
- Detection of large scale 3′ deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything? (2013) (14)
- Estimation of genotype relative risks from pedigree data by retrospective likelihoods (2010) (14)
- Linkage of nonspecific X-linked mental retardation to Xq21.31. (1992) (14)
- Uniparental disomy in congenital disorders: a prospective study. (1995) (14)
- Tumor necrosis factor-alpha allelic frequency and chromosome 6 allelic imbalance in patients with colorectal cancer. (1996) (14)
- Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG (2012) (14)
- SNP interaction pattern identifier (SIPI): an intensive search for SNP‐SNP interaction patterns (2016) (14)
- Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array (2016) (14)
- Pediatric duodenal cancer and biallelic mismatch repair gene mutations (2009) (14)
- Hb seal rock [(α2)142 term→Glow, Codon 142 TAA→GAA]: An extended α chain variant associated with Anemia, Microcytosis, and α-Thalassemia-2 (- 3.7 Kb)a (1997) (13)
- Overall survival result and outcomes by KRAS, BRAF, and DNA mismatch repair in relation to primary tumor site in colon cancers from a randomized trial of adjuvant chemotherapy: NCCTG (Alliance) N0147. (2014) (13)
- Reliability of diagnostic assessment of normal and premutation status in the fragile X syndrome using DNA testing. (1994) (13)
- Mutations in the RET proto-oncogene in sporadic pheochromocytomas (1994) (13)
- Adjuvant FOLFIRI with or without cetuximab in patients with resected stage III colon cancer: NCCTG Intergroup phase III trial N0147. (2011) (13)
- Fragile X syndrome: skin elastin abnormalities. (1987) (13)
- Aberrantly Methylated Gene Marker Levels in Stool: Effects of Demographic, Exposure, Body Mass, and Other Patient Characteristics (2012) (12)
- No fumarate hydratase (FH) mutations in hereditary prostate cancer (2003) (12)
- Polymorphisms in the 5alpha reductase type 2 gene and urologic measures of BPH. (2005) (12)
- The effect of sample size on polygenic hazard models for prostate cancer (2019) (12)
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- Confirmation of linkage of supravalvular aortic stenosis to the elastin gene on chromosome 7q. (1994) (12)
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- Pancreatic Cancer and a Novel MSH2 Germline Alteration (2011) (11)
- No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study (2021) (11)
- Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (11)
- National Cancer Institute Prostate Cancer Genetics Workshop. (2011) (11)
- Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes (2016) (11)
- Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene (2015) (11)
- The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium (2015) (11)
- HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG) (2012) (11)
- Erratum: DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy (Journal of the National Cancer Institute (2011) 103:11 (863-875)) (2011) (10)
- Fine mapping of familial prostate cancer families narrows the interval for a susceptibility locus on chromosome 22q12.3 to 1.36 Mb (2008) (10)
- Whole-Exome Sequencing of 10 Scientists: Evaluation of the Process and Outcomes. (2015) (10)
- PROCESSING OF PRECURSOR PROTEINS BY PREPARATIONS OF OVIDUCT MICROSOMES * (1980) (10)
- Hb Silver Springs [beta 131(H9)Gln-->His], a new hemoglobin variant found in six African-Americans. (1998) (10)
- Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk. (2006) (10)
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- Prognostic value of BRAF V600E and KRAS exon 2 mutations in microsatellite stable (MSS), stage III colon cancers (CC) from patients (pts) treated with adjuvant FOLFOX+/- cetuximab: A pooled analysis of 3934 pts from the PETACC8 and N0147 trials. (2015) (10)
- Experimental Designs for Array Comparative Genomic Hybridization Technology (2013) (9)
- Prevalence and clinical significance of HFE gene mutations in patients with iron overload (2000) (9)
- Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report (2021) (9)
- Erratum: MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps (Gastroenterology (2004) 127 (9-16) PII: S0016-5085(04)00580-3 and DOI: 10.1053/j.gastro.2004.03.070) (2004) (9)
- How well do whole exome sequencing results correlate with medical findings? A study of 89 Mayo Clinic Biobank samples (2015) (9)
- gsSKAT: Rapid gene set analysis and multiple testing correction for rare‐variant association studies using weighted linear kernels (2017) (9)
- Stability of BAT26 in Lynch syndrome colorectal tumours (2007) (9)
- Primary splenic lymphocyte-depletion Hodgkin's disease. (1990) (9)
- Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with Fusobacterium nucleatum and Its Subspecies animalis (2021) (9)
- CpG Island Methylator Phenotype in Human Colorectal Cancer Is Tightly Associated with BRAF Mutation and Underlies Sporadic Mismatch Repair Deficiency. (2006) (9)
- Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array (2016) (9)
- Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance). (2017) (9)
- Association of mitochondrial DNA copy number with self-rated health status (2018) (9)
- Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations (2012) (9)
- Parent of origin effects on age at colorectal cancer diagnosis (2010) (9)
- Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status (2016) (8)
- Tumor budding in colorectal carcinoma (2015) (8)
- Role of HPC 2 / ELAC 2 in Hereditary Prostate Cancer 1 (2001) (8)
- Segregation of the fragile X mutation from a male with a full mutation: unusual somatic instability in the FMR-1 locus. (1996) (8)
- Exclusion of a primary gene defect at the HLA locus in familial idiopathic dilated cardiomyopathy. (1995) (8)
- Hemoglobin S/hemoglobin Osler: A case with 3 β globin chains. DNA sequence (AAT) proves that Hb Osler is β 145 Tyr→Asn (1996) (8)
- Search for chromosome instability in lymphocytes with germ-line mutations in DNA mismatch repair genes. (1998) (7)
- Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome (2019) (7)
- Hypermethylation of the hMLHl Promoter in Colon Cancer with Microsatellite Instability 1 (2006) (7)
- Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families (2012) (7)
- Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in All of Us Research Program Participants, 2 January to 18 March 2020 (2021) (7)
- Colorectal Tumour Microsatellite Instability Test Results: Perspectives from Patients (2004) (7)
- A simple assay for the screening of the cystic fibrosis allele in carriers of the Phe508 deletion mutation. (1990) (7)
- Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium (2022) (7)
- DNA sequence analysis proves Hb M-Milwaukee-2 is due to beta-globin gene codon 92 (CAC-->TAC), the presumed mutation of Hb M-Hyde Park and Hb M-Akita. (1998) (7)
- Germline miRNA DNA variants and the risk of colorectal cancer by subtype (2016) (6)
- Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case‐Control Sequencing Studies (2016) (6)
- Testing Genetic Linkage with Relative Pairs and Covariates by Quasi-Likelihood Score Statistics (2007) (6)
- Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium (2017) (6)
- Linkage relationships between DXS105, DXS98, and other polymorphic DNA markers flanking the fragile X locus. (1991) (6)
- The APC E 1317 Q Variant in Adenomatous Polyps and Colorectal Cancers 1 (2003) (6)
- Childhood cancers in families with and without Lynch syndrome (2015) (6)
- An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set (2019) (6)
- Discovery of common and rare genetic risk variants for colorectal cancer (2018) (6)
- The bcr gene in Philadelphia chromosome positive acute lymphoblastic leukemia. (1989) (6)
- Hb Seal Rock [(alpha 2)142 term-->Glu, codon 142 TAA-->GAA]: an extended alpha chain variant associated with anemia, microcytosis, and alpha-thalassemia-2 (-3.7 Kb). (1997) (6)
- Will molecular genetic markers help predict the clinical behavior of colorectal neoplasia? (1992) (6)
- Association Between Smoking and Molecular Subtypes of Colorectal Cancer (2021) (6)
- Postmenopausal Hormone Therapy and Colorectal Cancer Risk by Molecularly Defined Subtypes and Tumor Location (2020) (6)
- 1054 Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH (2015) (6)
- Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers (2018) (6)
- DNA Sequence Analysis Proves HB M-Milwaukee-2 is DUE to β-Globin Gene Codon 92 (CAC→TAC), The Presumed Mutation of HB M-Hyde Park HB M-Akita (1998) (6)
- Association of tumor infiltrating lymphocytes (TILs) with molecular subtype and prognosis in stage III colon cancers (CC) from a FOLFOX-based adjuvant chemotherapy trial. (2016) (5)
- Fragile X syndrome: linkage analysis in black and white populations. (1988) (5)
- Analysis of the estrogen receptor from human uterus and breast tumor tissue by isoelectric focusing. (1983) (5)
- Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database (2020) (5)
- Single-Nucleotide Polymorphisms Sequencing Identifies Candidate Functional Variants at Prostate Cancer Risk Loci (2019) (5)
- Influence of KRAS and BRAF mutational status and rash on disease-free survival (DFS) in patients with resected stage III colon cancer receiving cetuximab (Cmab): Results from NCCTG N0147. (2011) (5)
- Identification of the molecular genetic defect of patients with methemoglobin M Kankakee (M-Iwate), α87 (F8) His → Tyr: Evidence for an electrostatic model of αM hemoglobin assembly (1999) (5)
- Alpha 1-Antitrypsin Deficiency Allele Carriers among Lung Cancer Patients 1 (1999) (5)
- Prognostic impact of BRAF and KRAS mutations and their relationship to DNA mismatch repair (MMR) status in 2,686 stage III colon cancer patients (pts) treated in a phase III study of adjuvant FOLFOX with or without cetuximab: NCCTG N0147. (2012) (5)
- Minimum qualifications for directors: DNA-based genetic-testing laboratories [10] (1992) (5)
- Carrier identification of cystic fibrosis by recombinant DNA techniques. (1989) (4)
- Prevalence of HFE gene mutation in normal blood donors and in patients with iron overload (1998) (4)
- Publisher Correction: Shared heritability and functional enrichment across six solid cancers (2019) (4)
- Loss of expression of zymogen granule protein 16 in colorectal cancer (2005) (4)
- ROLE OF PROTEASES IN THE SECRETION OF LYSOZYME, OVOMUCOID, CONALBUMIN AND OVALBUMIN FROM THE CHICK OVIDUCT (1978) (4)
- Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (4)
- Identification of the molecular genetic defect of patients with methemoglobin M-Kankakee (M-Iwate), alpha87 (F8) His --> Tyr: evidence for an electrostatic model of alphaM hemoglobin assembly. (1999) (4)
- Mutation detection in colorectal cancers : direct sequencing of DNA mismatch repair genes. (2001) (4)
- Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures (2022) (4)
- KLK3 SNP–SNP interactions for prediction of prostate cancer aggressiveness (2021) (4)
- Signal-Regulated Kinase and Raf Proteins Negative Feedback Pathways between Extracellular BRAF V 600 E Disrupts AZD 6244-Induced Abrogation of Updated (2008) (4)
- Characteristics Associated With Recruitment and Re-contact in Mayo Clinic Biobank (2020) (4)
- Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair. (2008) (4)
- Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region. (2022) (3)
- A polymerase chain reaction-based test for spinal and bulbar muscular atrophy. (1996) (3)
- Linkage analysis using multiple DNA polymorphic markers in normal families and in families with fragile X syndrome (1988) (3)
- Affected relative pairs and simultaneous search for two‐locus linkage in the presence of epistasis (2007) (3)
- Recent applications of PCR in clinical laboratory medicine. (1994) (3)
- Abstracts (2011) (3)
- High-Throughput Processing to Preserve Viable Cells: A Precision Medicine Initiative Cohort Program Workshop. (2017) (3)
- Erratum: Diagnosis of α-1-antitrypsin deficiency: An algorithm of genotyping, phenotyping, and quantitation (Clinical Chemistry (2006) 52, (2236-2242) DOI: 10.1373/clinchem.2006.072991) (2007) (3)
- AA9int: SNP interaction pattern search using non‐hierarchical additive model set (2018) (3)
- Use of restriction fragment length polymorphism analysis for detecting carriers of "fragile X" syndrome. (1987) (3)
- Characterization of human plasma-derived exosomal RNAs by deep sequencing (2013) (3)
- Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (3)
- 1028 Comparison of the Clinical Prediction Model Premm1,2,6 With Colorectal Cancer Molecular Tumor Testing for Lynch Syndrome in the Colon Cancer Family Registry (2010) (3)
- Refined gene localization for MRX7. (1999) (3)
- Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (3)
- Eight novel polymorphisms in the dystrophin gene of african‐americans: The rate of polymorphism is high (1993) (3)
- Body mass index and molecular subtypes of colorectal cancer (2022) (3)
- HB Cook [β132(H10)Lys → Thr]: A New Hemoglobin Vart in A Southeast Asian Family (1996) (3)
- Familial risk of colon cancer is high in younger patients with intraductal papillary mucinous tumor of the pancreas (IPMT): Evaluation of a possible molecular mechanism (2001) (2)
- Mutator gene effect in colorectal cancer (1994) (2)
- Racial differences in KRAS/BRAF mutation rates and survival in colon cancer (NCCTG N0147 [Alliance]). (2014) (2)
- Hereditary Nonpolyposis Colorectal Cancer (2007) (2)
- Colorectal cancer cases with de novo germ-line mutations in MLH1, MSH2, and MSH6 from the Colon Cancer Family Registry. (2011) (2)
- 146 Diabetes Mellitus (DM) and Colorectal Cancer (CRC) Risk by Molecularly-Defined Subtypes in a Prospective Study of Older Women (2010) (2)
- Lynch syndrome TACSTD1 family with predominant colorectal cancer. (2010) (2)
- Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases (2022) (2)
- Analysis of time-dependent patterns of treatment effect and failure to explain the predictive role of deficient mismatch repair (dMMR) in stage II and III colon cancer (CC). (2010) (2)
- Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L 3 region on chromosome 22 q 12 as a risk locus (2010) (2)
- Abstract 574: Exosomal miR-1290 and miR-375 as prognostic markers in metastatic castrate resistant prostate cancer (2014) (2)
- Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis (2019) (2)
- Genetic testing for Prader-Willi and Angelman syndromes. (1995) (2)
- A modified method for quantifying urinary vanillylmandelic acid. (1987) (2)
- Minimum qualifications for directors: DNA-based genetic-testing laboratories. DNA Testing Subcommittee, Quality Assurance Committee, Council of Regional Networks for Genetic Services. (1992) (2)
- Correction: Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22 (2012) (2)
- Network-directed cis-mediator analysis of normal prostate tissue expression profiles reveals downstream regulatory associations of prostate cancer susceptibility loci (2017) (2)
- Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions (2019) (2)
- Clinical significance of tumor microsatellite instability and immunohistochemistry for mismatch repair deficiency in colorectal cancers (2005) (2)
- Detection of large scale 3′ deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything? (2013) (2)
- Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (2)
- Molecular abnormalities in colorectal cancer: Microsatellite instability pathway (1998) (2)
- Response to Li and Hopper. (2021) (2)
- Molecular subtyping of colon cancers and distinct prognostic groups [NCCTG N0147 (Alliance)]. (2014) (2)
- Tea and Chocolate Consumption and Colorectal Cancer Risk by Molecularly Defined Subtypes in a Prospective Cohort Study of Older Women: Presidential Poster: 2094 (2013) (2)
- A microRNA Transcriptome-wide Association Study of Prostate Cancer Risk (2022) (2)
- Prolactinoma as the first manifestation of Gardner's syndrome (2008) (2)
- Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG) (2011) (1)
- Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer (2017) (1)
- Colorectal Cancer Linkage on Chromosomes 4 q 21 , 8 q 13 , 12 q 24 , and 15 q 22 (2012) (1)
- Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2018) (1)
- Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants (2018) (1)
- Sequence analysis of the fragile X trinucleotide repeat: Correlations with stability and haplotype and implications for the origin of fragile X alleles (1994) (1)
- Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases (2023) (1)
- Colorectal cancer and self-reported tooth agenesis (2014) (1)
- Stool bat-26 testing as adjunct to screening sigmoidoscopy: A feasibility analysis (2001) (1)
- A novel, noninvasive, mRNA gene expression colon cancer screening methodology. (2010) (1)
- eRNA: a graphic user interface-based tool optimized for large data analysis from high-throughput RNA sequencing (2014) (1)
- Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases (2022) (1)
- Novel methods to enhance single strand conformation polymorphism (SSCP) senstivity and efficiency: Application to mutation detection in cystic fibrosis (CF) (1994) (1)
- Myriad Genetic Laboratories (2004) (1)
- Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk (2020) (1)
- Alterations in Patients with Microsatellite Instability-Low Colorectal Cancer 1 (2000) (1)
- Dystrophin analysis inidiopathic dilated cardiomyopathy (1993) (1)
- Alterations in cell proliferation and apoptosis in human colon cancers with microsatellite instability. (2006) (1)
- Hb Cook [beta 132(H10)Lys-->Thr]: a new hemoglobin variant in a southeast Asian family. (1996) (1)
- Tu1518 Smoking Adversely Affects Colon Cancer Survival and Relapse Rates (2013) (1)
- Abstract 3572: Methylated gene marker levels in stool: effects of demographic, drug, and body mass and other patient characteristics (2012) (1)
- Pubertal development and prostate cancer risk (2018) (1)
- Adenocarcinoma involving colonic hyperplastic polyps is associated with loss of DNA repair enzyme MLH-1 (1998) (1)
- Heritable epigenetic mutation of MLHI in a mother and daughter with Lynch syndrome (2010) (1)
- Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis (2020) (1)
- Model-based prediction of defective DNA mismatch repair using clinicopathological variables in stage II and III colon cancers. (2009) (1)
- DNA ploidy is a stronger prognostic variable compared to microsatellite instability or 18q allelic loss in patients with stages II and III colon cancer (2005) (1)
- Molecular markers and survival after recurrence in stage III colon cancers from NCCTG N0147 and NSABP C-08 adjuvant chemotherapy trials. (2016) (1)
- Abstract 5221: Linking the molecular profile of colorectal tumors to germline genetic and environmental risk factors (2016) (1)
- Lack of referral bias in genetic studies of prostate cancer. (2002) (1)
- Abstract 4732: Cis-expression QTL analysis of established risk variants for colorectal cancer (2011) (1)
- Familial recurrence risk with varying amount of family history (2019) (1)
- Diagnosis of (cid:1) -1-Antitrypsin Deficiency: An Algorithm of Quantitation, Genotyping, and Phenotyping (2006) (1)
- Abstract 1676: Associations between hormone therapy with incident colorectal cancer by p53 protein expression in a population-based cohort of older women (2012) (1)
- Erratum: Frequent loss of heterozygosity at 7q31.1 is associated with tumor aggressiveness and progression (Cancer Research (September 15, 1995) 55 (4114-4119)) (1996) (1)
- Short Report Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis (2019) (0)
- contrast, approximately 15—20%of colorectal neoplasms arise through a distinct genetic pathway characterized by microsatellite Instability (MSI) associated with frequent loss of expression of one of the DNA mismatch (2006) (0)
- Telomerase distinguishes renal cell carcinoma from renal oncocytoma (1997) (0)
- Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk. (2022) (0)
- Blood lipids and prostate cancer: a Mendelian randomization analysis PRACTICAL consortium (2020) (0)
- Functional haploinsufficiency of the elastin gene in patients with isolated supravalvular aortic stenosis (1999) (0)
- T2049 Exogenous Estrogen Use and Colorectal Cancer Risk, Overall and By Mismatch Repair Protein Expression Status, Among Older Women (2008) (0)
- Utilization of touch preparations and whole genome amplification for loss of heterozygosity analysis in prostate cancer (1994) (0)
- Abstract 630: Smoking is associated with risks of molecular subtypes of colorectal cancer (2019) (0)
- Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2018) (0)
- Role of tumor molecular and pathology features to estimate colorectal cancer risk for first-degree relatives (2014) (0)
- No association between androgen receptor gene polymorphisms and urologic measures of BPH in a community-based setting (2003) (0)
- Association analyses identify 31 new risk loci for colorectal cancer susceptibility (2019) (0)
- Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome (2019) (0)
- Association between germline variants and somatic mutations in colorectal cancer (2022) (0)
- Genetic linkage between fragile x syndrome and the gene for coagulation factor ix (1985) (0)
- Abstract 5102: Telomeres and survival in stage III colon cancers: Findings from NCCTG N0147 (Alliance) study (2014) (0)
- prevalent factor IX dimorphism Carrier testing in hemophilia B with an immunoassay that distinguishes a (2011) (0)
- Karen Snow-Bailey, Ph.D., 1961–2006 (2007) (0)
- DNA mismatch repair enzyme expression (hMLH1, hMSH2) in colorectal adenomas (2000) (0)
- Cancer Risks for PMS2-Associated Lynch Syndrome (vol 29, pg 2961, 2018) (2019) (0)
- Abstract 2636: Tumor-infiltrating cytotoxic T-cells are associated with improved survival of colorectal cancer patients (2016) (0)
- Large-scale transcriptome-wide association study identifies new prostate cancer risk regions (2018) (0)
- The utility of brief questionnaire in assessment of risk for hereditary colorectal cancer in a clinic setting (2001) (0)
- Childhood cancers in families with and without Lynch syndrome (2015) (0)
- Mendelian Randomization Causal Analysis Mendelian randomization study of height and risk of colorectal cancer (2015) (0)
- The association of global gene expression in human colon tumors with germline variation at rs6983267 on 8q24 suggests that this SNP is an eQTL hotspot (2009) (0)
- Subspecialty Clinics: Medical Genetics Carrier Identification of Cystic Fibrosis by Recombinant (1989) (0)
- Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions (2019) (0)
- Prognostic impact of KRAS and BRAFV600E mutations stratified by tumor site in resected stage III colon cancer patients treated with adjuvant mFOLFOX6 with or without cetuximab: NCCTG N0147 (Alliance). (2013) (0)
- Microsatellite Instability Promoter in Colon Cancer with hMLH 1 Hypermethylation of the Updated (2006) (0)
- cancer metastatic progression and chromosomal instability in colon , a novel noncoding RNA mapping to 8 q 24 , underlies CCAT 2 Material Supplemental (2013) (0)
- Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (2019) (0)
- Compound heterozygosity for α thalassemia-2 and hemoglobin seal rock produces mild Hb H disease: The α-globin chain mutation in Hb seal rock is a TAA→GAA transversion in the termination codon of the 5′ α2-globin gene (1996) (0)
- Abstract A82: Can telomere length be modified in healthy people? (2011) (0)
- Efficient recovery of proteins from multiple source samples after trizol® or trizol®LS RNA extraction and long-term storage (2013) (0)
- Abstract 3039: Evaluation of intra-tumoral pks+ E. coli, enterotoxigenic B. fragilis and Fusobacterium nucleatum, overall and in early onset disease, in colorectal cancer cases (2023) (0)
- Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database (2023) (0)
- Searching for epistasis and linkage heterogeneity by correlations of pedigree‐specific linkage scores (2008) (0)
- 284 - Potential Impact of Family History Based Screening Guidelines on Early Cancer Detection Among Individuals at Risk for Young Onset Colorectal Cancer (2018) (0)
- Activated EGFR as a prognostic marker in human colon cancer (2008) (0)
- Epidermal growth factor receptor expression correlates with histologic grade but not microsatellite instability in primary colon carcinomas. (2006) (0)
- Microsatellite instability but not thymidylate synthase is a prognostic variable in primary colon cancers from patients treated in 5-FU-based adjuvant studies. (2006) (0)
- Use of eQTL Analysis for the Discovery of Target Genes Identified by GWAS (2014) (0)
- Polymorphisms in genes involved in sex hormone metabolism and risk of benign prostatic hyperplasia (2005) (0)
- Abstract 2930: Novel colorectal cancer loci in multiplex-proficient mismatch repair families (2012) (0)
- High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry (2014) (0)
- AXIN2 Mutations in Sporadic Ampullary Carcinoma Correlate with Young Age Onset and Aggressive Phenotype (2010) (0)
- S1931 Colon Cancers With Defective DNA Mismatch Repair Show Reduced Recurrence, Delayed Time-to-Recurrence and Fewer Distant Metastases (2010) (0)
- 1 Title : Post-hoc Analysis for Detecting Individual Rare Variant Risk Associations using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies Running Title : Bayesian Probit Rare Variant Analysis (2017) (0)
- Abstract 5268: Interactions between genetic predictors of gene expression and dietary factors associated with risk of colorectal cancer (2018) (0)
- News and comments (1993) (0)
- Isolated supravalvular aortic stenosis is characterized by a spectrum of mutations within the elastin gene (1996) (0)
- Abstract 2247: Associations between total T-lymphocytes and colorectal cancer survival in a prospective cohort study of older women (2017) (0)
- Alcohol Intake and Colorectal Cancer Risk by KRAS Mutation Status Among Older Women (2011) (0)
- S1950 Folate Intake and Colorectal Cancer Risks By CIMP and BRAF-Mutation Status Among Older Women (2009) (0)
- Altered MLH1 and MSH2 expression in colorectal cancer is associated with proximal site but not risk of metachronicity: Results of a case-control study (1998) (0)
- Contents Vol. 64, 2007 (2007) (0)
- 6009 Time-dependent patterns of treatment effect and failure as an explanation for the predictive role of deficient mismatch repair (dMMR) in stage II and III colon cancer (2009) (0)
- Abstract LB-348: Integrated analysis of microRNA and mRNA expression in microsatellite-stable colon cancer using next-generation sequencing and cDNA microarrays (2011) (0)
- Abstract 1286: Targeted deep sequencing of colorectal tumor tissues to study associations of tumor subtypes with germline genetic, lifestyle, and environmental risk factors (2017) (0)
- Abstract 2548: Targeted sequencing to identify rare variants in colorectal cancer. (2013) (0)
- Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy (2005) (0)
- Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study. (1), (2016) (0)
- Diabetes Mellitus and Colorectal Cancer Risk by KRAS Mutation Status Among Older Women (2011) (0)
- Abstract 2994: Constitutional telomere length correlates with colorectal cancer (CRC), but varies by age of cancer onset (2011) (0)
- O-009Prognostic value of BRAFV600E and KRAS exon 2 mutations in microsatellite stable stage III colon cancers from patients treated with FOLFOX + /- cetuximab: A pooled analysis from PETACC8 and N0147 trials (2015) (0)
- Abstract 4492: Colorectal cancer survival by molecular subtypes in a population-based cohort of older women (2012) (0)
- Detecting genomic clustering of risk variants from sequence data: cases versus controls (2013) (0)
- Pediatric colorectal carcinomas infrequently exhibit microsatellite instability or loss of expression of hMLH1 or hMSH2 (2001) (0)
- Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations (2012) (0)
- #607 Hemoglobin T-Cambodia: a new variant with 2 mutations (Hb E and Hb D-Punjab) confirmed by DNA sequencing (1996) (0)
- TITLE: Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk (2020) (0)
- Su1847 Alcohol Consumption and Colorectal Adenoma Risk Among Older Women (2012) (0)
- DNA mismatch repair enzyme (MLH1) status of aberrant crypt, foci and small polyps associated with MLH1-negative colon adenocarcinoma (1998) (0)
- The effect of sample size on polygenic hazard models for prostate cancer (2020) (0)
- Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (2019) (0)
- 104 Lack of referral bias in genetic studies of prostate cancer (2002) (0)
- Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2018) (0)
- Genome-Wide LinkageAnalysis of 1 , 233 Prostate Cancer Pedigrees Fromthe International Consortium for ProstateCancerGeneticsUsingNovel sumLINKandsumLODAnalyses (2010) (0)
- Abstract 4831: Additive and multiplicative gene-environment interactions for colorectal cancer risk. (2013) (0)
- Predict Colorectal Cancer icrosatellite Instability : A Population-Based Study (2007) (0)
- A Next Generation Stool DNA Test (NG-Sdna) for Colorectal Cancer Screening: Factors Affecting Neoplasm Detection (2011) (0)
- 471: Effect of a Family History of Prostate Cancer on Outcome After Radical Retropubic Prostatectomy (2004) (0)
- as truly distinctive biological markers or clearly defined pathogenetic mechanisms for this pathway are identified. (2001) (0)
- Risk of cancer in MSH6 mutation carriers: an international collaboration (2008) (0)
- Abstract 1677: Associations between cigarette smoking with incident colorectal cancer by p53 protein expression in a population-based cohort of older women: (2012) (0)
- hypervariable DNA probes and HLA-DR polymorphism T-cell-depleted bone marrow transplantation, as demonstrated by Third-party-mediated graft rejection and graft-versus-host disease after (2011) (0)
- Abstract 1151:cMYCamplification in colon cancer: A novel association withBRAFV600E and proficient DNA mismatch repair: (2012) (0)
- Abstract LB090: Associations of somatically mutated genes and pathways with colorectal cancer specific survival in 4,500 colorectal cancer patients (2021) (0)
- Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease (2013) (0)
- Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene (2015) (0)
- leukemia The bcr gene in Philadelphia chromosome positive acute lymphoblastic (2005) (0)
- An interactive strategy for the accurate characterization of transthyretin variants using combined proteomic and genomic technologies (2004) (0)
- A genetic hazard score to personalize prostate cancer screening, applied to population data (2019) (0)
- Some germ-line mutations in mismatch repair genes in HNPCC patients may confer an increased risk for additional germline defects (2002) (0)
- Mutations in the proapoptotic BAX gene are associated with defective DNA mismatch repair and altered tumor growth rates in human colon cancers (2007) (0)
- Abstract 1536: Whole genome sequencing of high-grade treatment-naïve prostate tumors (2014) (0)
- Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases (2015) (0)
- Interactions between genetic predictors of gene expression and dietary factors associated with risk of colorectal cancer (2018) (0)
- Shared heritability and functional enrichment across six solid cancers (2019) (0)
- Abstract A115: Alcohol use and molecularly defined colorectal cancer risks in a prospective study of older women (2010) (0)
- Abstract 2515: The Mayo Clinic Biobank - A growing resource for cancer related studies. (2013) (0)
- Abstract 229: Genome-wide association study by colorectal carcinoma subtype (2018) (0)
- Abstract 2145: Identification of genomic alterations and integrated gene expression profiles for MSS colon tumors (2010) (0)
- Exclusion of calcitonin/alpha-CGRP gene defect in a family with autosomal dominant supravalvular aortic stenosis. (1992) (0)
- Contents Vol. 139, 2013 (2013) (0)
- SimultaneousMeasurementof Estrogenand ProgesteroneReceptorsin TumorCytosolswith Use of 1251-Labeled Estradioland of 3H-R5020 (2004) (0)
- Abstract 3652: Hormone therapy and incident colorectal cancer risk by ER beta protein expression level in a population-based cohort of older women. (2013) (0)
- Abstract 2965: Functionally informed genome-wide interaction analysis of nonsteroidal anti-inflammatory drugs on colorectal cancer risk (2018) (0)
- A comprehensive analysis of clinical and tumor characteristics with BRAF and KRAS mutations status in adjuvant colon cancer trial N0147. (2012) (0)
- Abstract A44: Coffee consumption and colorectal cancer risk by molecularly defined subtypes in a prospective cohort study of older women (2013) (0)
- Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (2019) (0)
- Genetic correlates of therapeutic toxicities of stage III colon carcinoma patients treated with adjuvant FOLFOX+/-cetuximab (NCCTG N0147, Alliance). (2017) (0)
- Genetic Basis of Neurologic and Neuromuscular Diseases (2006) (0)
- Abstract 1892: Folate intake and incident colorectal cancer by KRAS mutation status in a population-based cohort of older women (2011) (0)
- Abstract 1891: Cigarette smoking and incident colorectal cancer by KRAS mutation status in a population-based cohort of older women (2011) (0)
- S2036 Pro-Apoptotic Bad and Bid Protein Expression Predict Survival in Stage II and III Colon Cancer Patients (2008) (0)
- Clinical HNPCC with no evidence for a role of DNA mismatch repair in cancer susceptibility (2007) (0)
- Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (2021) (0)
- Mendelian and Mitochondrial Inheritance, Gene Identification, and Clinical Testing (2005) (0)
- Microsatellite Instabifity in Colorectal Cancer : Different Mutator Phenotypes and the Principal Involvement of hMLHJ 1 (2006) (0)
- High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing (2018) (0)
- Gene symbol: HFE Disease: Hereditary hemochromatosis (2001) (0)
- Somatic PIK3CA mutations occur in later stage MSI(H) and MSS colorectal cancers (2006) (0)
- Abstract B40: Rare variant discovery in known cancer genes from whole-exome sequencingof African American hereditary prostate cancer families (2016) (0)
- Measurement of lactic and pyruvic acid on the cobas-bio centrifugal analyzer (1983) (0)
- S1963 Colon Cancers with Defective DNA Mismatch Repair Show Delayed Time-to-Recurrence and Differences in Patterns of Metastatic Spread (2009) (0)
- The usefulness of cytogenetic and DNA linkage analysis in counseling families with fragile X syndrome. (1990) (0)
- Detection of the BRAFV600E protein in human colon carcinomas by a mutation-specific antibody. (2013) (0)
- An Intronic RegionwithintheHuman FactorVilGene IsDuplicated within Xq28andIsHomologous tothe Polymorphic LocusDXSI15(767) (1989) (0)
- Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan (2020) (0)
- Abstract 4368: MicroRNAs miR-503 and -182 regulate FBXW7 contributing to the malignant transformation to colon adenocarcinoma (2014) (0)
- 169 Associations Between Cigarette Smoking and Incident Colorectal Cancer by ER Beta Protein Expression in a Population-Based Cohort of Older Women (2013) (0)
- Synchronous colorectal carcinoma: Presence and concordance of DNA mismatch repair enzyme expression (2000) (0)
- Reduced COX-2 protein expression in human colorectal cancer exhibiting defective mismatch repair (1998) (0)
- Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21 (2016) (0)
- Abstract 5518: Clinicopathologic associations with colorectal cancer molecular pathways in a cohort study of older women: (2012) (0)
- of sample on polygenic hazard models for prostate cancer. (2020) (0)
- Abstract 54: An miRNA transcriptome-wide association study of prostate cancer risk (2020) (0)
- Association of the HOXB13 G84E mutation with increased risk for prostate cancer and other malignancies. (2014) (0)
- Abstract 2742: Assessment of next generation platforms and use of duplicate runs for whole exome sequencing (2011) (0)
- Frequent Loss of Heterozygosity at 7q31.1 Is Associated with Tumor Aggressiveness and Progression (1996) (0)
- Hemoglobin S/hemoglobin Osler: a case with 3 beta globin chains. DNA sequence (AAT) proves that Hb Osler is beta 145 Tyr-->Asn. (1996) (0)
- College News: AMERICAN COLLEGE OF MEDICAL GENETICS (2000) (0)
- PRACTICAL (2016). Blood lipids and prostate cancer: a Mendelian randomization analysis. (2016) (0)
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