Stephen P. Bell
#82,626
Most Influential Person Now
American biochemist
Stephen P. Bell's AcademicInfluence.com Rankings
Stephen P. Bellbiology Degrees
Biology
#3817
World Rank
#5782
Historical Rank
Biochemistry
#2355
World Rank
#2504
Historical Rank

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Biology
Stephen P. Bell's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Stephen P. Bell Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephen P. Bell is an American biochemist. Bell earned a doctorate from the University of California, Berkeley, and teaches at the Massachusetts Institute of Technology, where he specializes in researching DNA replication and replisomes. He was named a Howard Hughes Medical Investigator in 2000. In 2009, Bell received the NAS Award in Molecular Biology and was named a member of the National Academy of Sciences itself in 2017. MIT appointed Bell the Uncas and Helen Whitaker Professor of Biology in 2018. He is a member of the Editorial Board for Genes & Development.
Stephen P. Bell's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA replication in eukaryotic cells. (2002) (2197)
- Genome-wide location and function of DNA binding proteins. (2000) (1534)
- ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex (1992) (1218)
- Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. (1986) (1027)
- The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. (2004) (854)
- Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase (1997) (792)
- Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins (1990) (566)
- Genome-Wide Distribution of ORC and MCM Proteins in S. cerevisiae: High-Resolution Mapping of Replication Origins (2001) (441)
- Yeast origin recognition complex functions in transcription silencing and DNA replication. (1993) (436)
- Initiation of DNA replication in eukaryotic cells. (1997) (412)
- Conserved nucleosome positioning defines replication origins. (2010) (353)
- Polymerases and the Replisome: Machines within Machines (1998) (326)
- Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. (2006) (320)
- The origin recognition complex: from simple origins to complex functions. (2002) (316)
- Coordination of replication and transcription along a Drosophila chromosome. (2004) (314)
- Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. (1988) (308)
- Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases (2011) (293)
- Nucleosomes positioned by ORC facilitate the initiation of DNA replication. (2001) (280)
- Chromosome Duplication in Saccharomyces cerevisiae (2016) (279)
- The multidomain structure of Orc1 p reveals similarity to regulators of DNA replication and transcriptional silencing (1995) (276)
- Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. (1999) (272)
- ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. (2004) (264)
- Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex (1997) (252)
- Drosophila ORC specifically binds to ACE3, an origin of DNA replication control element. (1999) (218)
- Architecture of the yeast origin recognition complex bound to origins of DNA replication (1997) (210)
- Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. (2001) (203)
- ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. (1999) (193)
- Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila (2007) (176)
- Mapping of Meiotic Single-Stranded DNA Reveals Double-Strand-Break Hotspots near Centromeres and Telomeres (2007) (176)
- Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading (2015) (168)
- Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. (2010) (167)
- Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. (2004) (163)
- Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading. (2007) (151)
- Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells. (2007) (147)
- Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. (2009) (146)
- Helicase loading at chromosomal origins of replication. (2013) (130)
- A genomic view of eukaryotic DNA replication (2005) (128)
- Assembly of alternative multiprotein complexes directs rRNA promoter selectivity. (1990) (123)
- ATPase switches controlling DNA replication initiation. (2000) (120)
- Subunit Organization of Mcm2-7 and the Unequal Role of Active Sites in ATP Hydrolysis and Viability (2008) (119)
- Molecular mechanisms governing species-specific transcription of ribosomal RNA (1989) (108)
- CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6. (2011) (107)
- The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF. (1989) (99)
- The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation (2001) (95)
- Cell-cycle control of the establishment of mating-type silencing in S. cerevisiae. (2002) (95)
- Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase. (2017) (92)
- Multiple functions for Mcm2-7 ATPase motifs during replication initiation. (2014) (90)
- Visualization of replication initiation and elongation in Drosophila (2002) (87)
- Regulation of origin recognition complex conformation and ATPase activity: differential effects of single‐stranded and double‐stranded DNA binding (2000) (83)
- The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level. (2015) (79)
- A conserved MCM single-stranded DNA binding element is essential for replication initiation (2014) (79)
- ATP bound to the origin recognition complex is important for preRC formation (2001) (77)
- Dynamics of Pre-replicative Complex Assembly* (2010) (74)
- Multiple Cdt1 molecules act at each origin to load replication‐competent Mcm2–7 helicases (2011) (69)
- Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes (2012) (63)
- Mechanism and Timing of Mcm2–7 Ring Closure During DNA Replication Origin Licensing (2017) (59)
- Eukaryotic replicators and associated protein complexes. (1995) (52)
- Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation. (2006) (52)
- Nucleosomes influence multiple steps during replication initiation (2017) (47)
- DNA replication and the cell cycle. (1992) (45)
- Cell cycle execution point analysis of ORC function and characterization of the checkpoint response to ORC inactivation in Saccharomyces cerevisiae (2006) (44)
- Mec 1 Is One of Multiple Kinases that Prime the Mcm 2-7 Helicase for Phosphorylation by Cdc 7 (2010) (35)
- 3 Assembly of Pre-replication Complexes (2006) (23)
- Mapping Subunit Location on the Saccharomyces cerevisiae Origin Recognition Complex Free and Bound to DNA Using a Novel Nanoscale Biopointer* (2004) (22)
- A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding (2019) (18)
- Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis (2018) (18)
- Replication origin–flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence (2017) (14)
- Orc 6 is required for dynamic recruitment of Cdt 1 during repeated Mcm 2 – 7 loading (2007) (14)
- Putting Two Heads Together to Unwind DNA (2009) (14)
- A helicase-tethered ORC flip enables bidirectional helicase loading (2021) (14)
- Rethinking origin licensing (2017) (12)
- DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7 (2020) (11)
- Binding Proteins Genome-Wide Location and Function of DNA (2008) (11)
- The replicon model and eukaryotic chromosomes. (1993) (10)
- Terminating the replisome (2014) (8)
- Multiple Cdt 1 molecules act at each origin to load replication-competent Mcm 2-7 helicases (2011) (7)
- CDK prevents Mcm 2 – 7 helicase loading by inhibiting Cdt 1 interaction with Orc 6 (2011) (6)
- Initiation-specific alleles of the Cdc45 helicase-activating protein (2019) (4)
- Conserved nucleosome positioning defines replication origins Material (2010) (2)
- Polymerases and the Replisome: Review Machines within Machines (1998) (1)
- Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms (2018) (1)
- PfMCM N-terminal domain without DNA (2014) (0)
- Editor's evaluation: Molecular determinants of phase separation for Drosophila DNA replication licensing factors (2021) (0)
- Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2–7 ring closing (2023) (0)
- MCM-ssDNA co-crystal structure (2014) (0)
- Bell and Kaguni Helicase Loading 1 Helicase Loading at Chromosomal Origins of Replication (2014) (0)
- Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms (2018) (0)
- 7.28 Molecular Biology, Spring 2001 (2001) (0)
- Dynamics of Pre-replicative Complex DNA and Chromosomes : (2010) (0)
- Cell division and the replicon (2000) (0)
- Assembly Dynamics of Pre-replicative Complex (2013) (0)
- Architecture and Evolutionary Stability of Yeast Signaling Pathways (2007) (0)
- Author response: A conserved MCM single-stranded DNA binding element is essential for replication initiation (2014) (0)
- Author response: Nucleosomes influence multiple steps during replication initiation (2017) (0)
- Single‐Molecule Studies of Eukaryotic DNA Replication (2016) (0)
- Incorporation into the pre‐replication complex activates the Mcm2‐7 replicative DNA helicase for phosphorylation by the S‐phase kinase, Cdc7‐Dbf4 (2009) (0)
- Distinct RPA functions promote eukaryotic DNA replication initiation and elongation (2022) (0)
- In vitro helicase loading and ORC binding on replicative and non‐replicative ACSs (2011) (0)
- EUKARYOTIC DNA REPLICATION & GENOME MAINTENANCE (2011) (0)
- Transcriptional Silencing, DNA-Replication, and the Yeast Origin Recognition Complex (1994) (0)
- Decision letter: Molecular determinants of phase separation for Drosophila DNA replication licensing factors (2021) (0)
- ATP bound to the origin reca important for preRC formatic (2016) (0)
- A role for the Speedy gene family in the early stages of mammalian meiosis (2008) (0)
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