Stephen Roger Holdsworth
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Immunology
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Biology
Stephen Roger Holdsworth's Degrees
- PhD Immunology University of Manchester
- Bachelors Biochemistry University of Manchester
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(Suggest an Edit or Addition)Stephen Roger Holdsworth's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids. (1999) (320)
- Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. (1999) (264)
- Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. (1981) (261)
- Characterisation of the onset and presenting clinical features of adult bronchiectasis. (2006) (232)
- Microbiologic follow-up study in adult bronchiectasis. (2007) (226)
- Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis. (2013) (204)
- Protease-Activated Receptor 1 Mediates Thrombin-Dependent, Cell-Mediated Renal Inflammation in Crescentic Glomerulonephritis (2000) (204)
- Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis (1997) (202)
- Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. (1999) (193)
- Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice. (1997) (181)
- Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis. (1998) (173)
- T cells in crescentic glomerulonephritis. (2006) (166)
- Th1 and Th17 cells induce proliferative glomerulonephritis. (2009) (165)
- Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. (2010) (165)
- Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells (2017) (158)
- The NLRP3 inflammasome in kidney disease and autoimmunity (2016) (155)
- Anti-neutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in anti-myeloperoxidase crescentic glomerulonephritis. (2006) (149)
- Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation. (1994) (148)
- Prominence of cell-mediated immunity effectors in "pauci-immune" glomerulonephritis. (1999) (141)
- T lymphocyte participation in antibody-induced experimental glomerulonephritis. (1985) (139)
- Immune modulation with interleukin‐4 and interleukin‐10 prevents crescent formation and glomerular injury in experimental glomerulonephritis (1997) (131)
- Outcome in Adult Bronchiectasis (2005) (129)
- PARTICIPATION OF CELL-MEDIATED IMMUNITY IN DEPOSITION OF FIBRIN IN GLOMERULONEPHRITIS (1988) (127)
- Intrinsic renal cells are the major source of tumor necrosis factor contributing to renal injury in murine crescentic glomerulonephritis. (2003) (125)
- Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function. (2013) (124)
- Neutrophil-Mediated Regulation of Innate and Adaptive Immunity: The Role of Myeloperoxidase (2016) (122)
- IFN-γ Mediates Crescent Formation and Cell-Mediated Immune Injury in Murine Glomerulonephritis (1999) (122)
- IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen. (2009) (120)
- Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis. (2015) (120)
- Antibody independent crescentic glomerulonephritis in mu chain deficient mice. (1997) (114)
- Role of mast cells in progressive renal diseases. (2008) (113)
- Mechanisms of T cell‐induced glomerular injury in anti‐glomeruler basement membrane (GBM) glomerulonephritis in rats (1997) (112)
- TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy. (2010) (112)
- IL‐12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis (1999) (106)
- Interleukin-4 and interleukin-10 attenuate established crescentic glomerulonephritis in mice. (1997) (105)
- The emergence of TH17 cells as effectors of renal injury. (2011) (105)
- A role for P selectin in complement-independent neutrophil-mediated glomerular injury. (1994) (104)
- Cytokines: Names and Numbers You Should Care About. (2015) (104)
- Adaptive immunity to nontypeable Haemophilus influenzae. (2003) (99)
- Glomerular macrophages produce reactive oxygen species in experimental glomerulonephritis. (1989) (98)
- Tumor necrosis factor production by glomerular macrophages in anti-glomerular basement membrane glomerulonephritis in rabbits. (1991) (97)
- Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit. (1985) (96)
- IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment. (2005) (93)
- Hydroxyl radical mediation of immune renal injury by desferrioxamine. (1986) (93)
- The requirement for granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in leukocyte-mediated immune glomerular injury. (2002) (90)
- Endogenous interleukin-10 regulates Th1 responses that induce crescentic glomerulonephritis. (2000) (88)
- Macrophage-induced glomerular injury. Cell transfer studies in passive autologous antiglomerular basement membrane antibody-initiated experimental glomerulonephritis. (1984) (85)
- Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis. (2007) (83)
- Histopathologic and clinical predictors of kidney outcomes in ANCA-associated vasculitis. (2014) (82)
- Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis. (2003) (82)
- Glomerular interleukin 1 production is dependent on macrophage infiltration in anti-GBM glomerulonephritis. (1991) (81)
- The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis (2012) (80)
- The Th17-defining transcription factor RORγt promotes glomerulonephritis. (2011) (80)
- Phenotypes of Adult Bronchiectasis: Onset of Productive Cough in Childhood and Adulthood (2009) (78)
- Interleukin-4 deficiency enhances Th1 responses and crescentic glomerulonephritis in mice. (1998) (76)
- IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis. (2009) (76)
- The participation of macrophages and monocytes in experimental immune complex glomerulonephritis. (1980) (75)
- IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis. (1999) (73)
- Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma. (2004) (73)
- Detection of intracellular lipocortin 1 in human leukocyte subsets. (1995) (71)
- Experimental autoimmune Goodpasture's disease: a pathogenetic role for both effector cells and antibody in injury. (2005) (70)
- P‐selectin directs T lymphocyte‐mediated injury in delayed‐type hypersensitivity responses: studies in glomerulonephritis and cutaneous delayed‐type hypersensitivity (1996) (70)
- Major Histocompatibility Complex Class II Expression by Intrinsic Renal Cells Is Required for Crescentic Glomerulonephritis (1998) (69)
- Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation. (2014) (69)
- Glomerular procoagulant activity in human proliferative glomerulonephritis. (1988) (69)
- Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis. (2011) (67)
- Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. (2004) (66)
- A pathogenetic role for mast cells in experimental crescentic glomerulonephritis. (2005) (63)
- The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. (2013) (63)
- IFN-γ Production by Intrinsic Renal Cells and Bone Marrow-Derived Cells Is Required for Full Expression of Crescentic Glomerulonephritis in Mice1 (2002) (63)
- Antiinflammatory Effect of Lipocortin 1 in Experimental Arthritis (1997) (62)
- Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis. (2001) (61)
- Renal dendritic cells adopt a pro-inflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis. (2012) (61)
- CYTOMEGALOVIRUS INFECTION COMPLICATING RENAL TRANSPLANTATION AND ITS RELATIONSHIP TO ACUTE TRANSPLANT GLOMERULOPATHY (1988) (61)
- Fc dependence of macrophage accumulation and subsequent injury in experimental glomerulonephritis. (1983) (60)
- Procoagulant activity expression by macrophages from atheromatous vascular plaques. (1989) (60)
- T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis. (2008) (60)
- Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis. (2010) (59)
- Interleukin-10 inhibits macrophage-induced glomerular injury. (2000) (58)
- Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction. (2012) (58)
- Distinct in vivo roles of CD80 and CD86 in the effector T‐cell responses inducing antigen‐induced arthritis (2008) (57)
- Tissue factor initiates glomerular fibrin deposition and promotes major histocompatibility complex class II expression in crescentic glomerulonephritis. (1997) (56)
- Nontypeable Haemophilus influenzae Induces Sustained Lung Oxidative Stress and Protease Expression (2015) (56)
- Th2 responses induce humorally mediated injury in experimental anti-glomerular basement membrane glomerulonephritis. (1997) (55)
- Glomerular tissue factor expression in crescentic glomerulonephritis. Correlations between antigen, activity, and mRNA. (1995) (54)
- Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice. (2011) (54)
- Endogenous Myeloperoxidase Is a Mediator of Joint Inflammation and Damage in Experimental Arthritis (2014) (54)
- Anti‐neutrophil monoclonal antibody therapy inhibits the development of adjuvant arthritis (1997) (54)
- Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis. (2012) (54)
- Interleukin‐10 inhibits experimental mesangial proliferative glomerulonephritis (2002) (54)
- CD80 and CD86 costimulatory molecules regulate crescentic glomerulonephritis by different mechanisms. (2005) (53)
- IL-18 Has IL-12-Independent Effects in Delayed-Type Hypersensitivity: Studies in Cell-Mediated Crescentic Glomerulonephritis1 (2000) (53)
- Endogenous foxp3(+) T-regulatory cells suppress anti-glomerular basement membrane nephritis. (2011) (53)
- Laboratory assessment of immune function in renal transplant patients. (2003) (52)
- Crescentic glomerulonephritis--a manifestation of a nephritogenic Th1 response? (2000) (51)
- The participation of macrophages, glomerular procoagulant activity, and factor VIII in glomerular fibrin deposition. Studies on anti-GBM antibody-induced glomerulonephritis in rabbits. (1986) (51)
- Contributions of IL-1β and IL-1α to Crescentic Glomerulonephritis in Mice (2004) (50)
- Lymphokine (MIF) production by glomerular T-lymphocytes in experimental glomerulonephritis. (1986) (48)
- Granulocyte macrophage colony-stimulating factor expression by both renal parenchymal and immune cells mediates murine crescentic glomerulonephritis. (2005) (48)
- Assessing immune function in adult bronchiectasis (2006) (47)
- Advances in the pathogenesis of Goodpasture's disease: from epitopes to autoantibodies to effector T cells. (2008) (47)
- Diagnosis of Mycobacterium tuberculosis infection using ESAT‐6 and intracellular cytokine cytometry (2005) (47)
- Leukocytes in glomerular injury (2007) (47)
- Biologics for the treatment of autoimmune renal diseases (2016) (47)
- Mast cells mediate acute kidney injury through the production of TNF. (2011) (47)
- C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis. (2017) (47)
- Tim-1 promotes cisplatin nephrotoxicity. (2011) (46)
- Glomerular macrophages express augmented procoagulant activity in experimental fibrin-related glomerulonephritis in rabbits. (1988) (45)
- T cells in glomerulonephritis (2003) (45)
- Glomerular fibrinolytic activity in anti-GBM glomerulonephritis in rabbits. (1993) (45)
- HLA and kidney disease: from associations to mechanisms (2018) (44)
- Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits. (1996) (43)
- ANCA-Associated Vasculitis: Pathogenesis, Models, and Preclinical Testing. (2017) (43)
- Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis. (2003) (43)
- CD100 Enhances Dendritic Cell and CD4+ Cell Activation Leading to Pathogenetic Humoral Responses and Immune Complex Glomerulonephritis1 (2006) (42)
- Role of CFTR mutations in adult bronchiectasis (2004) (42)
- Lung T-cell responses to nontypeable Haemophilus influenzae in patients with chronic obstructive pulmonary disease. (2013) (42)
- Anti-glomerular basement membrane antibody-induced experimental glomerulonephritis: evidence for dose-dependent, direct antibody and complement-induced, cell-independent injury. (1985) (39)
- CD8+ T Cells Effect Glomerular Injury in Experimental Anti-Myeloperoxidase GN. (2017) (39)
- Quantitation and characterization of glomerular procoagulant activity in experimental glomerulonephritis. (1987) (37)
- Delayed Diagnosis and Complications of Predominantly Antibody Deficiencies in a Cohort of Australian Adults (2018) (36)
- Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis (2009) (36)
- Airway inflammation in asymptomatic children with episodic wheeze (2006) (36)
- Glomerular expression of CD80 and CD86 is required for leukocyte accumulation and injury in crescentic glomerulonephritis. (2005) (35)
- Neutrophil Extracellular Traps: A Potential Therapeutic Target in MPO-ANCA Associated Vasculitis? (2021) (35)
- Formyl peptide receptor activation inhibits the expansion of effector T cells and synovial fibroblasts and attenuates joint injury in models of rheumatoid arthritis (2018) (35)
- Activated Renal Dendritic Cells Cross Present Intrarenal Antigens After Ischemia-Reperfusion Injury (2017) (35)
- The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease. (2006) (35)
- Pulmonary manifestations of the clinical syndrome of acute glomerulonephritis and lung hemorrhage. (1986) (34)
- A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity (2019) (33)
- Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis. (2012) (33)
- Cytotoxic T lymphocyte and natural killer cell responses to non‐typeable Haemophilus influenzae (2008) (33)
- Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN. (2013) (32)
- Immunopathogenesis of crescentic glomerulonephritis. (1999) (31)
- Review: T helper 17 cells: Their role in glomerulonephritis (2010) (31)
- Intrarenal antigens activate CD4+ cells via co-stimulatory signals from dendritic cells. (2008) (31)
- Contributions of IL-1beta and IL-1alpha to crescentic glomerulonephritis in mice. (2004) (30)
- Nonhepatitis B-associated liver disease in a renal transplant population. (1988) (30)
- Fibrin independent proinflammatory effects of tissue factor in experimental crescentic glomerulonephritis. (2004) (30)
- Animal Models of ANCA Associated Vasculitis (2020) (30)
- A comparison of fibrinolytic and defibrinating agents in established experimental glomerulonephritis. (1986) (30)
- Differential effects of steroids on leukocyte-mediated glomerulonephritis in the rabbit. (1984) (29)
- Systemic humoral immunity to non‐typeable Haemophilus influenzae (2008) (29)
- Tissue factor pathway inhibitor expression in human crescentic glomerulonephritis. (1999) (29)
- Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis. (2013) (29)
- Granulocyte independence of pulmonary oxygen toxicity in the rat. (1989) (28)
- BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity (2020) (27)
- Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis. (2010) (27)
- Leukocyte phenotype and function predicts infection risk in renal transplant recipients. (2005) (26)
- Renal Transplantation in Patients on CAPD (1986) (26)
- Pneumococcal vaccination in adult solid organ transplant recipients: A review of current evidence. (2018) (26)
- Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung (2017) (26)
- Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment. (2016) (26)
- Targeting leukocytes in immune glomerular diseases. (2008) (26)
- Chemokines as therapeutic targets in renal disease (2000) (26)
- Lung diffusing capacity in adult bronchiectasis: a longitudinal study. (2010) (25)
- Suppression of Autoimmunity and Renal Disease in Pristane‐Induced Lupus by Myeloperoxidase (2015) (25)
- Direct antiGBM antibody induced alterations in glomerular permselectivity. (1986) (24)
- Glomerulonephritis Induced by Heterologous Anti‐GBM Globulin as a Planted Foreign Antigen (2014) (23)
- Clinicopathological associations in mesangial IgA nephropathy. (1986) (23)
- Effect of cyclosporin A on antibody-induced experimental glomerulonephritis. (1985) (23)
- Alveolar macrophage procoagulant activity is increased in acute hyperoxic lung injury. (1988) (23)
- Regulatory T cells in immune‐mediated renal disease (2016) (23)
- Ex vivo lymphocyte proliferative function is severely inhibited in renal transplant patients on mycophenolate mofetil treatment. (2004) (22)
- Glomerular permselectivity in the isolated perfused rat kidney. (1985) (22)
- QUANTITATION OF INTRAGLOMERULAR MONONUCLEAR PHAGOCYTES IN EXPERIMENTAL GLOMERULONEPHRITIS IN THE RAT USING SPECIFIC MONOCLONAL ANTIBODIES (1987) (22)
- Cytokines in glomerulonephritis. (2007) (22)
- The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses. (2011) (21)
- Inducible co-stimulatory molecule ligand is protective during the induction and effector phases of crescentic glomerulonephritis. (2006) (21)
- Natural killer cell function predicts severe infection in kidney transplant recipients (2018) (19)
- B7.1 and B7.2 co‐stimulatory molecules regulate crescentic glomerulonephritis (2000) (19)
- Can immune biomarkers predict infections in solid organ transplant recipients? A review of current evidence. (2019) (18)
- MHC class I pathway is not required for the development of crescentic glomerulonephritis in mice (2000) (18)
- Intrarenal hemodynamic alterations induced by anti-GBM antibody. (1987) (18)
- FcγRIIB regulates T-cell autoreactivity, ANCA production, and neutrophil activation to suppress anti-myeloperoxidase glomerulonephritis. (2014) (18)
- Seroresponses and safety of 13‐valent pneumococcal conjugate vaccination in kidney transplant recipients (2018) (18)
- An IL-12-Independent Role for CD40-CD154 in Mediating Effector Responses: Studies in Cell-Mediated Glomerulonephritis and Dermal Delayed-Type Hypersensitivity1 (2004) (17)
- Endogenous IL-13 limits humoral responses and injury in experimental glomerulonephritis but does not regulate Th1 cell-mediated crescentic glomerulonephritis. (2004) (17)
- Wegener's granulomatosis: clinical features and outcome in seventeen patients. (1985) (17)
- Effect of interferon gamma and CD40 ligation on intracellular monocyte survival of nontypeable Haemophilus influenzae (2008) (17)
- Myeloperoxidase Peptide-Based Nasal Tolerance in Experimental ANCA-Associated GN. (2016) (17)
- Mast Cell Stabilization Ameliorates Autoimmune Anti-Myeloperoxidase Glomerulonephritis. (2016) (16)
- T Cell Mediated Autoimmune Glomerular Disease in Mice (2014) (15)
- Anti-basement membrane antibodies in immunologic renal disease. (1981) (15)
- Mitogen-induced T-cell CD69 expression is a less sensitive measure of T-cell function than [(3)H]-thymidine uptake. (1999) (15)
- Bactericidal activity of neutrophils with reduced oxidative burst from adults with bronchiectasis (2009) (14)
- Fibrinolytic therapy with streptokinase for established experimental glomerulonephritis. (1986) (14)
- Macrophage-Fc-receptor affinity: role in cellular mediation of antibody initiated glomerulonephritis. (1989) (14)
- Measurement of Anti‐DNA Antibodies by Elisa: A Comparative Study with Crithidia and a Farr Assay (1991) (14)
- Endogenous glucocorticoids modulate experimental anti‐glomerular basement membrane glomerulonephritis (2000) (14)
- Biologicals targeting T helper cell subset differentiating cytokines are effective in the treatment of murine anti-myeloperoxidase glomerulonephritis. (2019) (13)
- Signal transducer and activation of transcription 6 (STAT6) regulates T helper type 1 (Th1) and Th17 nephritogenic immunity in experimental crescentic glomerulonephritis (2011) (13)
- IL-1 RI deficiency ameliorates early experimental renal interstitial fibrosis (2009) (13)
- Tolerogenic Dendritic Cells Attenuate Experimental Autoimmune Antimyeloperoxidase Glomerulonephritis. (2019) (12)
- Acute Lithium Intoxication (2002) (12)
- Targeting IL-17 and IL-23 in Immune Mediated Renal Disease. (2015) (12)
- Suppression of Adjuvant Arthritis and Synovial Macrophage Inducible Nitric Oxide by N-iminoethyl-L-Ornithine, A Nitric Oxide Synthase Inhibitor (1997) (12)
- The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis. (2004) (11)
- Intrarenal Toll-like receptor 4 and Toll-like receptor 2 expression correlates with injury in antineutrophil cytoplasmic antibody-associated vasculitis. (2018) (11)
- Visualizing Macrophage Extracellular Traps Using Confocal Microscopy. (2017) (11)
- "Long-term" survival in light-chain myeloma with dialysis therapy alone. (1984) (11)
- Bronchiectasis (2006) (10)
- Evidence for direct renal injury as a consequence of glomerular complement activation. (1986) (9)
- Induced regulatory T cells are phenotypically unstable and do not protect mice from rapidly progressive glomerulonephritis (2017) (9)
- Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis (2015) (9)
- Relative contributions of chemo-attractant and terminal components of complement to anti-glomerular basement membrane (GBM) glomerulonephritis. (1989) (9)
- Role of the macrophage in immunologically induced glomerulonephritis. (1985) (9)
- The formation of glomerular crescents (2001) (8)
- Heterologous Immunity Between SARS-CoV-2 and Pathogenic Bacteria (2022) (8)
- Interleukin-17RA Promotes Humoral Responses and Glomerular Injury in Experimental Rapidly Progressive Glomerulonephritis (2016) (8)
- T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ. (2017) (8)
- Idiopathic Goodpasture’s Syndrome (1986) (8)
- Modulation of normobaric pulmonary oxygen toxicity by hydroxyl radical inhibition. (1987) (7)
- HLA-DR15-specific inhibition attenuates autoreactivity to the Goodpasture antigen. (2019) (7)
- β2 Integrin independent neutrophil recruitment and injury in anti‐GBM glomerulonephritis in rabbits (1994) (7)
- ANCA epitope specificity determines pathogenicity, detectability and clinical predictive value (2013) (7)
- The C3aR promotes macrophage infiltration and regulates ANCA production but does not affect glomerular injury in experimental anti-myeloperoxidase glomerulonephritis (2018) (6)
- Anti-CD20 mAb-Induced B Cell Apoptosis Generates T Cell Regulation of Experimental Myeloperoxidase ANCA-Associated Vasculitis (2021) (6)
- Pathogenic Role for γδ T Cells in Autoimmune Anti-Myeloperoxidase Glomerulonephritis (2017) (6)
- Rapid alterations in plasma aluminium in association with varied oral aluminium intake in dialysis patients. (1987) (6)
- Quantitation of the intrarenal uptake of immunoglobulin aggregates by macrophages in diffuse proliferative glomerulonephritis. (1986) (6)
- T lymphocyte participation in acute serum sickness glomerulonephritis in rabbits (1991) (6)
- Chest pain and exacerbations of bronchiectasis (2012) (6)
- Mouse models of anti-neutrophil cytoplasmic antibody-associated vasculitis. (2015) (5)
- Monoclonal Antibodies as Probes of Normal and Abnormal Renal Structure (1984) (5)
- Apoptotic Cell-Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN. (2019) (4)
- Absence of the lysosomal protein Limp‐2 attenuates renal injury in crescentic glomerulonephritis (2014) (4)
- Immune-mediated kidney disease in 2017: Progress in mechanisms and therapy for immunological kidney disease (2018) (4)
- Acute pulmonary and renal injury after administration of heterologous anti-lung antibodies in the rat. Characterization of ultrastructural binding sites, basement membrane epitopes, and inflammatory mediation systems. (1991) (4)
- A radioimmunoassay for the detection of circulating anti-glomerular basement membrane antibodies. (1983) (4)
- Localization of antiglomerular basement membrane-binding polyclonal antibodies in rat lung and kidney using post-embedding immunogold electron microscopy. (1989) (4)
- A simple score can identify kidney transplant recipients at high risk of severe infection over the following 2 years (2019) (4)
- OX40 ligand is inhibitory during the effector phase of crescentic glomerulonephritis (2018) (4)
- Programmed death 1 and its ligands do not limit experimental foreign antigen‐induced immune complex glomerulonephritis (2015) (4)
- Detection of anti-DNA antibodies: a comparison between two Farr assays, Crithidia luciliae and a human chromosomal substrate assay. (1988) (4)
- Comparison of immunofluorescence and immunoperoxidase for demonstration of antinuclear antibodies on HEp-2 substrate. (1987) (3)
- Phagocyte extracellular traps in children with neutrophilic airway inflammation (2021) (3)
- The mechanism of action of corticosteroids on glomerular injury in acute serum sickness in rabbits. (1985) (3)
- MicroRNA-155 a new therapeutic target in crescentic GN. (2013) (3)
- The (re)challenging question of erythropoiesis-stimulating agents inducing pure red cell aplasia. (2008) (3)
- 209. INHIBITION OF PEPTIDYLARGININE DEIMINASE 4 LIMITS NEUTROPHIL EXTRACELLULAR TRAP FORMATION AND INFLAMMATION IN EXPERIMENTAL ANTI MPO-ANCA GLOMERULONEPHRITIS (2019) (3)
- Nephritogenic immune reactions involving immune complex formation in the circulation and in situ within the kidney. (1981) (2)
- Ageing enhances cellular immunity to myeloperoxidase and experimental anti-myeloperoxidase glomerulonephritis. (2021) (2)
- Emerging Cellular Therapies for Anti-myeloperoxidase Vasculitis and Other Autoimmune Diseases (2021) (2)
- Antithyroid and antiadrenal autoantibodies in antiglomerular basement membrane disease, thin basement membrane disease and Alport syndrome (1998) (2)
- A new experimental model of in-situ immune complex disease of the lung. (1988) (2)
- Cell-Mediated Crescentic Glomerulonephritis Delayed-Type Hypersensitivity : Studies in IL-18 Has IL-12-Independent Effects in and (2000) (2)
- Interleukin-4 Is Not A Crucial Mediator of Renal Injury in Th2 Prone Mice With Glomerulonephritis (1998) (2)
- Nontypeable haemophilus influenzae (NTHi) and lung oxidative stress (2013) (2)
- Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis (2023) (1)
- T cells direct macrophage recruitment and giant cell formation but not proliferation in experimental crescentic glomerulonephritis (1998) (1)
- FMS-Like Tyrosine Kinase 3 Ligand Treatment Does Not Ameliorate Experimental Rapidly Progressive Glomerulonephritis (2015) (1)
- Tubular antigen-associated renal disease in New Zealand white rabbits. II. Investigation of mediators of glomerular injury: localization and characterization of the glomerular capillary wall antigen. (1988) (1)
- Idiopathic Goodpasture's syndrome. Fatal pulmonary haemorrhage and crescentic glomerulonephritis in the absence of immune-reactant deposition. (1986) (1)
- ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap (2016) (1)
- SAT-012 Peptidyl Arginase Deiminase 4 inhibition attenuates inflammation in murine experimental myeloperoxidase cytoplasmic antibody associated glomerulonephritis (2019) (1)
- Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis. (2020) (1)
- Raised immunoglobulin E and idiopathic bronchiectasis (2008) (1)
- Measurement of Humoral Immune Competence and the Risk of Sinopulmonary Infection in a Cohort of Kidney Transplant Recipients. (2018) (1)
- The renal draining lymph nodes in acute inflammatory kidney disease. (2019) (1)
- Immune Activation in Experimental Glomerulonephritis (2010) (0)
- Prominence of Cell-Mediated Immunity in "Pauci-immune" Glomerulonephritis (GN) (1998) (0)
- Modulation of Experimental Crescentic Glomerulonephritis by TH2 Cytokines (1998) (0)
- Cell-mediated Immunity in Glomerulonephritis (1991) (0)
- Reply (2007) (0)
- Ischaemia/reperfusion in rat renal cortex: vesicle leakiness and Na+, K+-ATPase activity in membrane preparations (2009) (0)
- The Pathogenesis of Antineutrophil Cytoplasmic Antibody Renal Vasculitis (2013) (0)
- The lung immune response to bacteria in chronic obstructive pulmonary disease. (2015) (0)
- The NLRP 3 inflammasome in kidney disease and autoimmunity Running title : Inflammasomes in kidney disease (2016) (0)
- Cardiovascular , Pulmonary and Renal Pathology Interleukin-17 A Promotes Early but Attenuates Established Disease in Crescentic Glomerulonephritis in Mice (2011) (0)
- Endogenous IL-17A promotes pristane-induced systemic autoimmunity and experimental lupus nephritis (BA4P.218) (2014) (0)
- MHC CLASS II HUMANIZED MICE DEFINE A T CELL EPITOPE IN GOODPASTURE'S DISEASE (2008) (0)
- Cardiovascular , Pulmonary , and Renal Pathology The IL-27 Receptor Has Biphasic Effects in Crescentic Glomerulonephritis Mediated Through Th 1 Responses (2011) (0)
- Reply: To PMID 23142009. (2013) (0)
- Chapter 3 Pathogenesis of Renal Disease: Cytokines and Other Soluble Factors (2007) (0)
- Dermal Delayed-Type Hypersensitivity Cell-Mediated Glomerulonephritis and in Mediating Effector Responses : Studies in An IL-12-Independent Role for CD 40-CD 154 (2004) (0)
- Role of TLR4 in anti-MPO antibody induced glomerular and pulmonary neutrophil influx (2009) (0)
- Stimulation of PAI‐1 in rabbit anti‐GBM glomerulonephritis (1998) (0)
- Using HLA DRB1*1501 transgenic mice to study the HLA‐linked autoimmune Goodpasture's disease (2008) (0)
- DOMINANT HLA-MEDIATED PROTECTION FROM THE RISK OF AUTOIMMUNE RENAL DISEASE IS CONFERRED BY ANTIGEN-SPECIFIC REGULATORY T CELLS (2017) (0)
- A novel approach to a rare case of non-islet cell hypoglycaemia (2021) (0)
- INTRINSIC RENAL CELL DERIVED TUMOUR NECROSIS FACTOR‐α IS A MAJOR CONTRIBUTOR TO MURINE CRESCENTIC GLOMERULONEPHRITIS (2002) (0)
- Microbiologic profile in bronchiectasis (2001) (0)
- Pathways of cellular adaptive immunity in autoimmune crescentic glomerulonephritis and lupus nephritis (2011) (0)
- Delayed antigen-specific CD4(+) cell proliferation in the kidney (2005) (0)
- Functional evidence of T cell involvement in experimental crescentic GNa (2006) (0)
- The authors reply. (2013) (0)
- Major Histocompatibility Complex Class II (MHC II) Expression by Intrinsic Glomerular Cells is Required for Antigen Recognition in Crescentic Glomerulonephritis (1998) (0)
- Platelet fatty acids and peripheral blood lymphocyte subsets in an institutionalized elderly population. (1998) (0)
- The Effects of CTLA4-Ig Treatment on Anti-GBM Glomerulonephritis In Th2 Prone Balb/c Mice (1998) (0)
- Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric (2012) (0)
- ABSTRACTS 001 INTERLEUKIN 17- RECEPTOR A (IL-17RA) ON LEUKOCYTES AND TISSUE CELLS MEDIATES INFLAMMATION IN A MURINE MODEL OF CRESCENTIC GLOMERULONEPHRITIS (2013) (0)
- Attenuation of Proliferative Glomerulonephritis in Thrombin Receptor (PAR-1) Deficient Mice: Evidence For A Non-Coagulant Role of Thrombin in Glomerular Injury (1998) (0)
- CD40‐CD40L COSTIMULATION IS REQUISITE FOR BOTH THE INITIATION OF IMMUNE RESPONSES AND FOR EFFECTOR RESPONSES IN CRESCENTIC GLOMERULONEPHRITIS (GN) (2002) (0)
- Glomerulonephritis in Mice Full Expression of Crescentic Bone Marrow-Derived Cells Is Required for Production by Intrinsic Renal Cells and γ IFN-Kitching (2002) (0)
- Autoimmune responses to the Goodpasture antigen are driven primarily by IL‐23 and are IL‐12 independent (2008) (0)
- Procoagulant Activity in Diseases of The Kidney (2019) (0)
- Dominant protection from HLA-mediated autoimmune disease is conferred by antigen specific regulatory T cells (2018) (0)
- Tissue Factor/Factor VIIA Receptor/Ligand Interactions Augment Macrophage Activation (1998) (0)
- SAT-013 TOLEROGENIC CD40-DEFICIENT DENDRITIC CELLS ATTENUATE ANTI-MYELOPEROXIDASE VASCULITIS BY INDUCING REGULATORY B CELLS (2019) (0)
- Endogenous Interferon-y is an Important Mediator of Glomerular Cresent Formation and Cell Mediated Glomerular injury (1998) (0)
- Proinflammatory Cytokines in Glomerulonephritis (1991) (0)
- Immunological kidney diseases (WS-098) Chairpersons: Yasuhiko Tomino, Jan Novak (2010) (0)
- Cell mediated injury in autoimmune anti-glomerular basement membrane disease is defined by a critical T cell epitope in humanized mice (123.33) (2012) (0)
- Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung (2017) (0)
- Atorvastatin enhances humoral immune responses but does not alter renal injury in experimental crescentic glomerulonephritis (2009) (0)
- Stimulation of PAI‐1 in rabbit anti‐GBM glomerulonephritis (1998) (0)
- Mechanisms of Glomerular Fibrin Deposition in Glomerulonephritis (1991) (0)
- IN ANTI-GBM DISEASE, HLA-PEPTIDE CONFORMATION DETERMINES SUSCEPTIBILITY OR PROTECTION FROM DISEASE (2017) (0)
- Conversion of the liver into a biofactory for DNaseI using adeno-associated virus vector gene transfer reduces neutrophil extracellular traps in a model of Systemic Lupus Erythematosus. (2022) (0)
- Supplementary Material for: Interleukin-17RA Promotes Humoral Responses and Glomerular Injury in Experimental Rapidly Progressive Glomerulonephritis (2016) (0)
- Tissue Factor Pathway Inhibitor and Its Correlation with Tissue Factor and Fibrin in Human Crescentic Glomerulonephritis (1998) (0)
- Interleukin-12 Directs Th1 Responses and Crescent Formation in Glomerulonephritis (1998) (0)
- The immunodominant CD4+ T cell epitope of myeloperoxidase induces cell mediated injury in murine anti-myeloperoxidase glomerulonephritis (159.14) (2012) (0)
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