Stephen Holgate

Q: What Schools Are Affiliated With Stephen Holgate

Stephen Holgate is affiliated with the following schools: University of York, University College London, University of British Columbia, Vanderbilt University, Royal Postgraduate Medical School, University of Southampton

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Stephen Holgate

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#1431

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#2607

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#202

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#441

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Philosophy

Why Is Stephen Holgate Influential?

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According to Wikipedia, Sir Stephen Townley Holgate, is a British physician who specializes in immunopharmacology, respiratory medicine and allergies, and asthma and air pollution, based at the University of Southampton and University Hospital Southampton NHS Foundation Trust, UK.

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Stephen Holgate 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Air pollution and health (2002) (2646)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (1973)
Community study of role of viral infections in exacerbations of asthma in 9-11 year old children (1995) (1932)
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response (2000) (1869)
Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. (1990) (1653)
Mucosal inflammation in asthma. (1990) (1302)
Mast-cell infiltration of airway smooth muscle in asthma. (2002) (1262)
SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS (1989) (1175)
Cellular events in the bronchi in mild asthma and after bronchial provocation. (1989) (1173)
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness (2002) (1105)
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus (2005) (1011)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (961)
Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. (1999) (892)
Induction of nitric oxide synthase in asthma (1993) (881)
Role of deficient type III interferon-λ production in asthma exacerbations (2006) (879)
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. (1994) (873)
Innate and adaptive immune responses in asthma (2012) (790)
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2019) (762)
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma (2003) (750)
Treatable traits: toward precision medicine of chronic airway diseases (2016) (707)
Myofibroblasts and subepithelial fibrosis in bronchial asthma. (1990) (702)
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. (2010) (687)
International Consensus Report on Diagnosis and Treatment of Asthma. (1992) (685)
Treatment strategies for allergy and asthma (2008) (657)
Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. (1992) (643)
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. (2004) (620)
The epidemic of allergy and asthma (1999) (617)
Reliability: What is it, and how is it measured? (2000) (614)
Role of deficient type III interferon-lambda production in asthma exacerbations. (2006) (613)
The role of the mast cell in the pathophysiology of asthma. (2006) (576)
The airway epithelium: Structural and functional properties in health and disease (2003) (573)
The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis. (1996) (566)
Epithelial-mesenchymal interactions in the pathogenesis of asthma. (2000) (559)
Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. (1998) (554)
Alveolar tissue inflammation in asthma. (1996) (554)
Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation. (1993) (551)
Rhinoviruses infect the lower airways. (2000) (541)
Airway remodeling in asthma: new insights. (2003) (536)
Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study (2002) (533)
Involvement of the epidermal growth factor receptor in epithelial repair in asthma (2000) (528)
Defective epithelial barrier function in asthma. (2011) (520)
Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma. (2013) (498)
Efficacy and safety of a recombinant anti‐immunoglobulin E antibody (omalizumab) in severe allergic asthma (2004) (496)
Tumour necrosis factor (TNFα) as a novel therapeutic target in symptomatic corticosteroid dependent asthma (2005) (484)
Epithelium dysfunction in asthma. (2007) (473)
Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed (2020) (450)
Pathogenesis of Asthma (2008) (441)
The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. (2005) (441)
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. (2009) (424)
Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid. (1997) (416)
Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response (2000) (409)
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. (1983) (405)
The sentinel role of the airway epithelium in asthma pathogenesis (2011) (404)
The mechanisms, diagnosis, and management of severe asthma in adults (2006) (400)
The effect of treatment with omalizumab, an anti‐IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma (2005) (399)
Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects. (1995) (384)
Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society. (1999) (378)
Asthma and Rhinitis (1995) (355)
Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization (2015) (346)
The airway epithelium is central to the pathogenesis of asthma. (2008) (345)
Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways. (2000) (341)
Risk of first‐generation H1‐antihistamines: a GA2LEN position paper (2010) (338)
Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. (1991) (333)
T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. (1996) (331)
The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men. (1984) (324)
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. (2002) (323)
Heterogeneity of human mast cells based on cytokine content. (1995) (314)
Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. (2003) (313)
The biodiversity hypothesis and allergic disease: world allergy organization position statement (2013) (311)
Personal exposure to nitrogen dioxide (NO2) and the severity of virus-induced asthma in children (2003) (302)
Severe asthma in adults: what are the important questions? (2007) (293)
Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist. (1992) (286)
Effect of bronchoconstriction on airway remodeling in asthma. (2011) (284)
Environmental risk factors and allergic bronchial asthma (2005) (281)
A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies. (2013) (278)
A self management plan in the treatment of adult asthma. (1989) (278)
Growth of prepubertal children with mild asthma treated with inhaled beclomethasone dipropionate. (1995) (275)
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. (2001) (274)
Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel (2004) (273)
Bronchial mucosal manifestations of atopy: a comparison of markers of inflammation between atopic asthmatics, atopic nonasthmatics and healthy controls. (1992) (272)
Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma. (2004) (271)
Genetics of allergic disease. (2010) (268)
Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD (2004) (258)
Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects. (1995) (256)
Early and late-phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. I. The association of disordered airway physiology to leukocyte infiltration. (1988) (255)
Eridothelin immunoreactivity of airway epithelium in asthmatic patients (1991) (255)
Use of polymerase chain reaction for diagnosis of picornavirus infection in subjects with and without respiratory symptoms (1993) (252)
Viruses and bacteria in acute asthma exacerbations – A GA2LEN‐DARE* systematic review (2010) (252)
The contribution of transforming growth factor-β and epidermal growth factor signalling to airway remodelling in chronic asthma (2006) (251)
Early life risk factors for adult asthma: a birth cohort study of subjects at risk. (2001) (251)
Predicting and evaluating response to omalizumab in patients with severe allergic asthma. (2007) (250)
A defective type 1 response to rhinovirus in atopic asthma (2002) (249)
Natural history of asthma in childhood--a birth cohort study. (1991) (243)
Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. (2005) (241)
A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. (2002) (238)
Nonspecific bronchial reactivity and its relationship to the clinical expression of asthma. A longitudinal study. (1989) (235)
Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1. (1995) (233)
Asthma (2015) (232)
Safety and tolerability of omalizumab (2009) (231)
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial (2020) (231)
Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. (2004) (229)
Protection against allergen-induced asthma by salmeterol (1990) (225)
Release of RANTES, MIP-1 alpha, and MCP-1 into asthmatic airways following endobronchial allergen challenge. (1997) (223)
The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial. (2014) (219)
Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma. (1999) (216)
Leukotriene antagonists and synthesis inhibitors: new directions in asthma therapy. (1996) (214)
The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma (1999) (212)
The epithelium takes centre stage in asthma and atopic dermatitis. (2007) (211)
Lymphocyte and eosinophil influx into alveolar tissue in nocturnal asthma. (1999) (211)
Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast (2000) (211)
Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial (2003) (210)
A new look at the pathogenesis of asthma (2009) (208)
Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells1 (2002) (207)
Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways. (1994) (207)
Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. (2007) (203)
Anti‐immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti‐inflammatory activity and clinical efficacy (2005) (203)
Characterization of wheezing phenotypes in the first 10 years of life (2003) (202)
The role of the airway epithelium and its interaction with environmental factors in asthma pathogenesis. (2009) (200)
Influence of albuterol, cromolyn sodium and ipratropium bromide on the airway and circulating mediator responses to allergen bronchial provocation in asthma. (2015) (198)
Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma. (1997) (197)
Epithelial stress and structural remodelling in childhood asthma (2005) (197)
Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways (2009) (196)
Genetic and environmental interaction in allergy and asthma☆☆☆ (1999) (196)
Analysis of novel disease-related genes in bronchial asthma. (2002) (194)
β-ADRENERGIC AGONIST RESISTANCE IN NORMAL HUMAN AIRWAYS (1977) (194)
The relationship between pneumonia in early childhood and impaired lung function in late adult life. (1994) (194)
The role of mast cell tryptase in regulating endothelial cell proliferation, cytokine release, and adhesion molecule expression: tryptase induces expression of mRNA for IL-1 beta and IL-8 and stimulates the selective release of IL-8 from human umbilical vein endothelial cells. (1998) (192)
Epithelial damage and response. (2000) (192)
Adenosine inhibits and potentiates IgE-dependent histamine release from human lung mast cells by an A2-purinoceptor mediated mechanism. (1984) (189)
Adenosine A2B receptors: a novel therapeutic target in asthma? (1998) (187)
Prevalence of respiratory symptoms among 7 and 11 year old schoolchildren and association with asthma. (1989) (186)
Predicting persistent disease among children who wheeze during early life (2003) (185)
The contribution of histamine to immediate bronchoconstriction provoked by inhaled allergen and adenosine 5' monophosphate in atopic asthma. (1987) (184)
The role of a soluble TNFα receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial (2008) (182)
Consensus group on new‐generation antihistamines (CONGA): present status and recommendations (2003) (181)
Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review (2012) (180)
IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations (2007) (180)
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research (2020) (178)
Immunohistochemical identification of mast cells in formaldehyde‐fixed tissue using monoclonal antibodies specific for tryptase (1990) (176)
Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised double blind placebo controlled trial (1997) (175)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (174)
The ARRIVE guidelines 2019: updated guidelines for reporting animal research (2019) (173)
Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome (2005) (173)
Omalizumab in asthma: an update on recent developments. (2014) (172)
Release of mast-cell-derived mediators after endobronchial adenosine challenge in asthma. (1995) (170)
The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics. (1997) (168)
Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release. (1984) (168)
The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. (1997) (167)
Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study (1997) (165)
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma. (1986) (165)
The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma. (1991) (165)
Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. (2000) (163)
Characterization of histamine secretion from mechanically dispersed human lung mast cells: effects of anti-IgE, calcium ionophore A23187, compound 48/80, and basic polypeptides. (1982) (159)
Methods for the assessment of endobronchial biopsies in clinical research: application to studies of pathogenesis and the effects of treatment. (2003) (158)
Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma. (1992) (158)
Asthmatic Bronchial Epithelium Is More Susceptible to Oxidant-Induced Apoptosis (2002) (158)
IL-4 Receptor α Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets1 (2006) (157)
Early identification of interleukin-16 (lymphocyte chemoattractant factor) and macrophage inflammatory protein 1 alpha (MIP1 alpha) in bronchoalveolar lavage fluid of antigen-challenged asthmatics. (1995) (157)
Allergic diseases and asthma: a major global health concern. (2012) (157)
The mouse trap: It still yields few answers in asthma. (2006) (156)
Polymorphisms in the interleukin‐4 and interleukin‐4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population (2003) (154)
Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. (2005) (153)
Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke. (2002) (153)
Immunopathology and human mast cell cytokines. (1999) (152)
The protective effect of inhaled leukotriene D4 receptor antagonist ICI 204,219 against exercise-induced asthma. (1993) (152)
Altered airway surfactant phospholipid composition and reduced lung function in asthma. (2000) (151)
The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects. (1992) (150)
A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects (2007) (148)
Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. (2001) (147)
The expression of leukocyte-endothelial adhesion molecules is increased in perennial allergic rhinitis. (1992) (146)
Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. (2001) (146)
Interleukin‐4 and ‐13 expression is co‐localized to mast cells within the airway smooth muscle in asthma (2003) (145)
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma (2003) (145)
Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities. (2006) (144)
Efficacy and safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial (2010) (144)
IgE-dependent expression of mRNA for IL-4 and IL-5 in human lung mast cells. (1995) (143)
Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches? (2011) (143)
Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial (2002) (143)
Toll-like receptor 4 polymorphism and severity of atopy in asthmatics (2004) (142)
The role of mast cells and basophils in inflammation. (2000) (142)
Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium. (2001) (142)
'Every breath we take: the lifelong impact of air pollution' - a call for action. (2017) (141)
Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs. (1980) (141)
Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction. (1989) (140)
Peak flow based asthma self-management: a randomised controlled study in general practice. British Thoracic Society Research Committee. (1995) (140)
The inflammatory effects of 2 ppm NO2 on the airways of healthy subjects. (1997) (140)
Cellular infiltration of the airways in asthma of varying severity. (1996) (140)
Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline. (1984) (140)
Bronchial angiogenesis in severe glucocorticoid-dependent asthma. (2000) (140)
Expression of ErbB receptors and mucins in the airways of long term current smokers (2004) (139)
Animal models of asthma: value, limitations and opportunities for alternative approaches. (2011) (139)
The long-acting beta2-agonist salmeterol xinafoate: effects on airway inflammation in asthma. (1999) (139)
Challenges and approaches for the development of safer immunomodulatory biologics (2013) (138)
The effects of regular inhaled formoterol, budesonide, and placebo on mucosal inflammation and clinical indices in mild asthma. (1999) (138)
Tear and conjunctival changes during the allergen-induced early- and late-phase responses. (2000) (137)
Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-β in bronchial epithelial cells from donors with asthma (2010) (136)
Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis. (2008) (135)
Expression of c-erbB receptors and ligands in human bronchial mucosa. (1999) (135)
The natural history of respiratory symptoms in a cohort of adolescents. (1998) (135)
Effect of atopy on the natural history of symptoms, peak expiratory flow, and bronchial responsiveness in 7- and 8-year-old children with cough and wheeze. A 12-month longitudinal study [published errarum appears in Am Rev Respir Dis 1992 Aug;146(2):540]. (1991) (135)
Severe eosinophilic asthma: a roadmap to consensus (2017) (134)
Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium. (2003) (133)
Relation between chest expansion, pulmonary function, and exercise tolerance in patients with ankylosing spondylitis. (1990) (132)
Effects of budesonide and formoterol on NF-kappaB, adhesion molecules, and cytokines in asthma. (2001) (132)
Concentration response functions for ultrafine particles and all-cause mortality and hospital admissions: results of a European expert panel elicitation. (2009) (131)
Adenosine-induced bronchoconstriction in asthma: role of mast cell-mediator release. (1985) (130)
TNF α is localized to nasal mucosal mast cells and is released in acute allergic rhinitis (1995) (130)
Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways. (1996) (130)
Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms (2007) (129)
Interaction of neuropeptides with human mast cells. (1989) (129)
Allergic eye disease mechanisms (1998) (128)
Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. (2009) (127)
Rhinovirus infection up‐regulates eotaxin and eotaxin‐2 expression in bronchial epithelial cells (2001) (127)
ADAM33 polymorphism: association with bronchial hyper‐responsiveness in Korean asthmatics (2004) (126)
Health effects of acute exposure to air pollution. Part I: Healthy and asthmatic subjects exposed to diesel exhaust. (2003) (126)
Effects of omalizumab on markers of inflammation in patients with allergic asthma (2009) (125)
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. (1990) (125)
Comparative airway response to inhaled bradykinin, kallidin, and [des-Arg9]bradykinin in normal and asthmatic subjects. (1990) (124)
NF-κB and TNF-α: A Positive Autocrine Loop in Human Lung Mast Cells? (2002) (124)
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. (2001) (124)
Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. (2002) (123)
Antioxidant kinetics in lung lavage fluid following exposure of humans to nitrogen dioxide. (1996) (123)
The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects. (1997) (122)
Efficacy of Omalizumab, an Anti-immunoglobulin E Antibody, in Patients with Allergic Asthma at High Risk of Serious Asthma-related Morbidity and Mortality* (2001) (122)
Genetic susceptibility to the respiratory effects of air pollution (2008) (121)
Dendritic cells in normal and asthmatic airways: expression of the α subunit of the high affinity immunoglobulin E receptor (FcεRI‐α) (1996) (120)
The bronchial epithelium as a target for inflammatory attack in asthma (1992) (120)
Human mast cells express stem cell factor (1998) (120)
Leucocyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhinitis. (1993) (120)
Exposure to nitrogen dioxide (NO2) and respiratory disease risk. (1998) (119)
The influence of increased bronchial responsiveness, atopy, and serum IgE on decline in FEV1. A longitudinal study in the elderly. (1995) (119)
The use of omalizumab in the treatment of severe allergic asthma: A clinical experience update. (2009) (119)
The free radical basis of air pollution: focus on ozone. (1995) (119)
The anti-inflammatory effects of leukotriene-modifying drugs and their use in asthma. (2001) (119)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* (2020) (117)
The cellular and mediator basis of asthma in relation to natural history (1997) (117)
The pathogenesis and significance of bronchial hyper-responsiveness in airways disease. (1987) (117)
Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. (2011) (117)
Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood (2011) (116)
Endothelin in bronchoalveolar lavage fluid and its relation to airflow obstruction in asthma. (1995) (116)
Cytokine immunoreactivity in seasonal rhinitis: regulation by a topical corticosteroid. (1995) (116)
Does dietary intake of vitamins C and E influence lung function in older people? (1996) (116)
Mechanisms of virus induced exacerbations of asthma. (1997) (116)
Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma (2003) (115)
Effects of 0.2 ppm ozone on biomarkers of inflammation in bronchoalveolar lavage fluid and bronchial mucosa of healthy subjects. (1998) (115)
Dynamics of pro-inflammatory and anti-inflammatory cytokine release during zcute inflammation in chronic obstructive pulmonary disease: an ex vivo study (2008) (115)
Mediator and cytokine mechanisms in asthma. (1993) (115)
The Brussels Declaration: the need for change in asthma management (2008) (114)
Persistent airway inflammation but accommodated antioxidant and lung function responses after repeated daily exposure to nitrogen dioxide. (1999) (112)
The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma. (1999) (112)
Cytokine profiles of BAL T cells and T‐cell clones obtained from human asthmatic airways after local allergen challenge (1999) (112)
Adhesion molecules and their role in inflammation. (1991) (111)
The effect of an increase in inhaled allergen dose after rimiterol hydrobromide on the occurrence and magnitude of the late asthmatic response and the associated change in nonspecific bronchial responsiveness. (1989) (111)
Profound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients. (1997) (110)
Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline. (1985) (109)
Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma? (1997) (109)
The mast cell as a primary effector cell in the pathogenesis of asthma. (1986) (109)
Adenosine inhibits and potentiates IgE‐dependent histamine release from human basophils by an A2‐receptor mediated mechanism (1983) (109)
IL-5 increases expression of 5-lipoxygenase-activating protein and translocates 5-lipoxygenase to the nucleus in human blood eosinophils. (1999) (108)
Effect of omalizumab on peripheral blood eosinophilia in allergic asthma. (2010) (108)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) (107)
Bronchoconstrictor properties of preservatives in ipratropium bromide (Atrovent) nebuliser solution. (1987) (107)
Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? (2001) (106)
Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways. (2015) (103)
ADAM33 expression in asthmatic airways and human embryonic lungs. (2005) (102)
The effect of treatment with oral corticosteroids on asthma symptoms and airway inflammation. (1997) (100)
The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma. (2008) (100)
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever. (1984) (100)
Circulating adhesion molecules in asthma. (1994) (99)
Phenotypic characterization of T cells infiltrating the conjunctiva in chronic allergic eye disease. (1996) (99)
Basic fibroblast growth factor in asthma: measurement in bronchoalveolar lavage fluid basally and following allergen challenge. (2001) (99)
Production and characterization of monoclonal antibodies specific for human mast cell tryptase (1990) (99)
Mechanisms of virus‐induced asthma exacerbations: state‐of‐the‐art. A GA2LEN and InterAirways document (2007) (99)
Interleukin-5 production by human airway epithelial cells. (1999) (97)
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms. (1996) (96)
TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair. (2002) (96)
Identifying and prioritizing uncertainties: patient and clinician engagement in the identification of research questions. (2010) (95)
European allergy white paper: allergic diseases as a public health problem in Europe (1997) (95)
Asthma control or severity: that is the question (2007) (95)
Amplified rhinovirus colds in atopic subjects (1994) (95)
The Quintiles Prize Lecture 2004: The identification of the adenosine A2B receptor as a novel therapeutic target in asthma (2005) (94)
Neuropeptide-containing nerves in endobronchial biopsies from asthmatic and nonasthmatic subjects. (1995) (94)
Free and complexed interleukin-8 in blood and bronchial mucosa in asthma. (1997) (94)
9 alpha,11 beta-prostaglandin F2, a novel metabolite of prostaglandin D2 is a potent contractile agonist of human and guinea pig airways. (1987) (94)
Tumour necrosis factor alpha: a polcnlial mediator of asthma (1995) (94)
Mucosal inflammation and asthma. (1994) (93)
The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. (2004) (93)
Asthma out of control? A structured review of recent patient surveys (2006) (92)
Asthma genetics: waiting to exhale (1997) (92)
The effect of the orally active platelet-activating factor antagonist WEB 2086 in the treatment of asthma. (1994) (91)
Could the airway epithelium play an important role in mucosal immunoglobulin A production? (1999) (91)
TNF-α-mediated bronchial barrier disruption and regulation by src-family kinase activation. (2013) (91)
Expression of CD44 isoforms is increased in the airway epithelium of asthmatic subjects. (1997) (91)
Asthma genetics and personalised medicine. (2014) (91)
Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma (2014) (91)
Kinetic Analysis of the Interleukin-13 Receptor Complex* (2002) (90)
Astemizole, a potent histamine H1-receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels. (1984) (90)
Proteomics of bronchial biopsies: galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients. (2014) (90)
Associations between respiratory symptoms, bronchial response to methacholine, and atopy in two age groups of schoolchildren. (1989) (90)
Aspirin Exacerbated Respiratory Disease (2012) (90)
Reduced selenium status of patients with asthma. (1989) (89)
Asthma in the elderly: what we know and what we have yet to know (2014) (89)
B7 costimulation is required for IL-5 and IL-13 secretion by bronchial biopsy tissue of atopic asthmatic subjects in response to allergen stimulation. (1999) (89)
Exposure, uptake, distribution and toxicity of nanomaterials in humans. (2010) (89)
A New Era of Targeting the Ancient Gatekeepers of the Immune System: Toll-Like Agonists in the Treatment of Allergic Rhinitis and Asthma (2014) (89)
The genetics of asthma: ADAM33 as an example of a susceptibility gene. (2006) (89)
Seasonal allergic conjunctivitis is accompanied by increased mast cell numbers in the absence of leucocyte infiltration (1997) (88)
IL-13 receptor alpha 2: a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts. (2006) (88)
The future of technologies for personalised medicine. (2012) (88)
The role of Toll-like receptors and related receptors of the innate immune system in asthma (2006) (88)
Chronic fatigue syndrome: understanding a complex illness (2011) (87)
Effect of oral terfenadine on the bronchoconstrictor response to inhaled histamine and adenosine 5'-monophosphate in non-atopic asthma. (1987) (87)
Asthma: a dynamic disease of inflammation and repair. (1997) (87)
Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5'-monophosphate. (1989) (87)
Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies (1994) (87)
The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma. (1989) (87)
Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma. (1994) (87)
Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man. (1987) (86)
Adamalysins in biology and disease (2009) (86)
Inhaled lysine-aspirin as a bronchoprovocation procedure in aspirin-sensitive asthma: its repeatability, absence of a late-phase reaction, and the role of histamine. (1989) (85)
Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma (2003) (85)
The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma (2003) (85)
Peripheral blood CD4+ and CD8+ T cell type 1 and type 2 cytokine production in atopic asthmatic and normal subjects (2002) (85)
Detection of rhinovirus infection of the nasal mucosa by oligonucleotide in situ hybridization. (1994) (85)
The role of the eosinophil in asthma. (1991) (85)
Antihistamines in asthma. (1989) (82)
Variability and lack of predictive ability of asthma end-points in clinical trials (2002) (82)
The rising trends in asthma (1997) (82)
Cell adhesion molecules and the bronchial epithelium. (1993) (82)
Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium (2008) (82)
Do lower respiratory tract infections in early childhood cause chronic obstructive pulmonary disease? (1995) (81)
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. (2009) (81)
Co‐localization of immunoreactive transforming growth factor‐beta1 and decorin in bronchial biopsies from asthmatic and normal subjects (1998) (80)
Physiotherapy breathing retraining for asthma: a randomised controlled trial (2018) (80)
Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease (2002) (80)
The 1992 Cournand Lecture. Asthma: past, present and future. (1993) (79)
Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores. (1998) (79)
Health impact and toxicological effects of nanomaterials in the lung (2012) (79)
Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects. (2002) (79)
The response of plasma histamine to bronchoprovocation with methacholine, adenosine 5'-monophosphate, and allergen in atopic nonasthmatic subjects. (1990) (78)
Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma. (2003) (78)
Rethinking the pathogenesis of asthma. (2009) (78)
Factors associated with mortality after an asthma admission: a national United Kingdom database analysis. (2007) (77)
A Brief History of Asthma and Its Mechanisms to Modern Concepts of Disease Pathogenesis (2010) (76)
Bronchoconstrictor and antibronchoconstrictor properties of inhaled prostacyclin in asthma. (1988) (76)
A new method of quantification of the pulmonary regional distribution of aerosols using combined CT and SPECT and its application to nedocromil sodium administered by metered dose inhaler. (1994) (76)
Influence of interleukin-8 challenge in the nasal mucosa in atopic and nonatopic subjects. (1994) (76)
Mast cell tryptase and histamine concentrations in bronchoalveolar lavage fluid from patients with interstitial lung disease. (1991) (75)
Association of Tumor Necrosis Factor-α Polymorphisms and Ozone-induced Change in Lung Function (2005) (75)
Ozone‐induced bronchial epithelial cytokine expression differs between healthy and asthmatic subjects (2003) (75)
Description of Pulmonary Deposition of Radiolabeled Aerosol by Airway Generation Using a Conceptual Three Dimensional Model of Lung Morphology (1995) (75)
Role of tumor necrosis factor alpha in asthma. (2004) (74)
Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study. (1996) (73)
Rhinovirus infection induces major histocompatibility complex class I and costimulatory molecule upregulation on respiratory epithelial cells. (2000) (73)
New targets for allergic rhinitis — a disease of civilization (2003) (73)
Personal exposure to nitrogen dioxide and risk of airflow obstruction in asthmatic children with upper respiratory infection (2000) (72)
The contribution of neurogenic reflexes to hypertonic saline-induced bronchoconstriction in asthma. (1993) (72)
Leukocyte recruitment after local endobronchial allergen challenge in asthma. Relationship to procedure and to airway interleukin-8 release. (1996) (72)
Asthma: the importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma. (2002) (72)
Ozone-induced lung function decrements do not correlate with early airway inflammatory or antioxidant responses. (1999) (72)
Changes in sputum counts and airway hyperresponsiveness after budesonide: monitoring anti-inflammatory response on the basis of surrogate markers of airway inflammation. (2002) (71)
Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4 (2007) (71)
Adenosine-induced bronchoconstriction in asthma. Role of parasympathetic stimulation and adrenergic inhibition. (1985) (70)
World Allergy Organization guidelines for prevention of allergy and allergic asthma. (2004) (70)
Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine. (1989) (70)
Corticosteroids inhibit rhinovirus-induced intercellular adhesion molecule-1 up-regulation and promoter activation on respiratory epithelial cells. (2000) (70)
The relative contribution of mast cell subsets to conjunctival TH2-like cytokines. (2001) (70)
Effects of ozone on epithelium and sensory nerves in the bronchial mucosa of healthy humans. (1997) (70)
Toxicological mechanisms underlying oxidant pollutant-induced airway injury. (1998) (69)
Adverse reactions to the non-drug constituents of nebuliser solutions. (1988) (69)
Invited Lecture: Activation of the Epithelial Mesenchymal Trophic Unit in the Pathogenesis of Asthma (2001) (69)
Immunolocalization of cytokines to mast cells in normal and allergic conjunctiva (1997) (69)
Sputum IL-6 concentrations in severe asthma and its relationship with FEV1 (2010) (69)
Inhibition of adenosine 5'-monophosphate- and methacholine-induced bronchoconstriction in asthma by inhaled frusemide. (1990) (69)
Every breath we take: The lifelong impact of air pollution, Report of a working party. (2016) (69)
Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma. (1990) (68)
Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response (2012) (68)
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma. (1991) (68)
Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease. (2004) (68)
Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. (2008) (68)
Bacterial contamination of home nebuliser. (1987) (67)
Granulocyte recruitment by human mast cell tryptase. (1995) (67)
Mast cell numbers and staining characteristics in the normal and allergic human conjunctiva. (1991) (67)
Prevalence of atopy and range of bronchial response to methacholine in 7 and 11 year old schoolchildren. (1989) (67)
Does non-specific bronchial responsiveness indicate the severity of asthma? (1990) (67)
Relationship between mediator release from human lung mast cells in vitro and in vivo. (1985) (67)
Essential Role for Both CD80 and CD86 Costimulation, But Not CD40 Interactions, in Allergen-Induced Th2 Cytokine Production from Asthmatic Bronchial Tissue: Role for αβ, But Not γδ, T Cells (1999) (66)
Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. (2011) (66)
Is electrodermal testing as effective as skin prick tests for diagnosing allergies? A double blind, randomised block design study (2001) (66)
Airway remodelling in asthma and novel therapy. (2013) (66)
The candidate region approach to the genetics of asthma and allergy. (1997) (65)
Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium (2005) (65)
Barrier Disrupting Effects of Alternaria Alternata Extract on Bronchial Epithelium from Asthmatic Donors (2013) (65)
Asthma: a simple concept but in reality a complex disease (2011) (65)
Identification of neutrophil chemotactie factors in bronchoalveolar lavage fluid of asthmatic patients (1997) (65)
Inhaled synthetic surfactant abolishes the early allergen-induced response in asthma (2003) (64)
The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma. (1993) (64)
Effects of indomethacin on cyclic nucleotide levels and histamine release from rat serosal mast cells. (1979) (64)
The interaction between immunoglobulin E and smoking in airflow obstruction in the elderly. (1992) (64)
Adhesion molecules and relationship to leukocyte levels in allergic eye disease. (1998) (64)
Production of IL-8 and IL-4 by positively and negatively selected CD4+ and CD8+ human T cells following a four-step cell separation method including magnetic cell sorting (MACS). (1996) (63)
Role of cysteinyl leukotrienes in adenosine 5`-monophosphate induced bronchoconstriction in asthma (2002) (63)
Mast cells, mediators and asthma (1985) (63)
Mast cell derived mediators (1998) (63)
Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis. (2000) (62)
Basement membrane pores in human bronchial epithelium: a conduit for infiltrating cells? (2001) (62)
A MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells (2014) (62)
Investigative use of bronchoscopy, lavage and bronchial biopsies in asthma and other airways diseases. (1992) (62)
Antioxidant consumption and repletion kinetics in nasal lavage fluid following exposure of healthy human volunteers to ozone. (1999) (62)
The anaphylaxis hypothesis of sudden infant death syndrome (SIDS): mast cell degranulation in cot death revealed by elevated concentrations of tryptase in serum (1994) (62)
The effect of cromolyn sodium and albuterol on early and late phase bronchoconstriction and airway leukocyte infiltration after allergen challenge of nonanesthetized guinea pigs. (1988) (62)
Barrier responses of human bronchial epithelial cells to grass pollen exposure (2012) (62)
Effect of regular inhaled beclomethasone on exercise and methacholine airway responses in school children with recurrent wheeze. (1995) (61)
Mucosal nerves in endobronchial biopsies in asthma and non-asthma. (1991) (61)
On the generation of allergic airway diseases: from GM-CSF to Kyoto. (2002) (61)
Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways (2003) (61)
Case-control study of salmeterol and near-fatal attacks of asthma. (1998) (61)
Astemizole and other H1-antihistaminic drug treatment of asthma. (1985) (60)
A population survey of respiratory symptoms in the elderly. (1991) (60)
Increased levels of IL-4 in CD8+ T cells in atopic asthma. (1997) (59)
Lack of association of HLA class I genes and TNF α‐308 polymorphism in toluene diisocyanate‐induced asthma (2004) (59)
Mechanisms of Asthma and Implications for Its Prevention and Treatment: A Personal Journey (2013) (59)
The inhibitory effect of nebulized albuterol on the early and late asthmatic reactions and increase in airway responsiveness provoked by inhaled allergen in asthma. (1991) (59)
Mast cell and histamine content of human bronchoalveolar lavage fluid. (1985) (58)
Non-biological Particles and Health (1995) (58)
Duration of growth suppressive effects of regular inhaled corticosteroids (1998) (58)
Biomarker Profiles in Asthma With High vs Low Airway Reversibility and Poor Disease Control. (2015) (57)
Health effects of acute exposure to air pollution. Part II: Healthy subjects exposed to concentrated ambient particles. (2003) (57)
Enhanced upregulation of smooth muscle related transcripts by TGFβ2 in asthmatic (myo) fibroblasts (2006) (57)
Paradoxical bronchoconstriction in asthmatic patients after salmeterol by metered dose inhaler. (1992) (57)
Ciliated cell damage in the bronchial epithelium of asthmatics and non‐asthmatics (1993) (57)
The epidemic of asthma and allergy. (2004) (57)
A look at the pathogenesis of asthma: the need for a change in direction. (2010) (56)
Rhinovirus‐induced alterations on peripheral blood mononuclear cell phenotype and costimulatory molecule expression in normal and atopic asthmatic subjects (2002) (56)
The Role of Inflammatory Processes in Airway Hyperresponsiveness. (1989) (56)
Leukotriene and prostanoid pathway enzymes in bronchial biopsies of seasonal allergic asthmatics. (2001) (56)
Role of B7-CD28/CTLA-4 Costimulation and NF-κB in Allergen-Induced T Cell Chemotaxis by IL-16 and RANTES1 (2000) (56)
Risk factors and characteristics associated with severe and difficult to treat asthma phenotype: an analysis of the ENFUMOSA group of patients based on the ECRHS questionnaire (2005) (56)
Compromised concentrations of ascorbate in fluid lining the respiratory tract in human subjects after exposure to ozone. (1999) (56)
Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma. (1990) (56)
Immunoreactive endothelin in bronchial biopsy specimens: increased expression in asthma and modulation by corticosteroid therapy. (1997) (56)
Airway and metabolic resistance to intravenous salbutamol: a study in normal man. (1980) (56)
Regulation of pulmonary T cell responses to inhaled antigen: role in Th1- and Th2-mediated inflammation. (1999) (56)
Trends in asthma mortality (1997) (56)
The health effects of fine particulate air pollution (2019) (56)
Inflammatory processes and bronchial hyperresponsiveness (1991) (55)
The bronchial epithelium in asthma--much more than a passive barrier. (2001) (55)
Promoter polymorphism in the 5‐lipoxygenase (ALOX5) and 5‐lipoxygenase‐activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population (2003) (55)
対談 "ASTHMA AND OUTDOOR AIR POLLUTION"について (1995) (55)
Human mast cell tryptase stimulates the release of an IL‐8‐dependent neutrophil chemotactic activity from human umbilical vein endothelial cells (HUVEC) (2000) (54)
Three-dimensional description of pulmonary deposition of inhaled aerosol using data from multimodality imaging. (1996) (54)
Adenosine as a bronchoconstrictor mediator in asthma and its antagonism by methylxanthines. (1984) (54)
Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. (2001) (54)
Absorption and disposition kinetics of cromolyn sodium and the influence of inhalation technique. (1987) (54)
Humidification as an adjunct to chest physiotherapy in aiding tracheo-bronchial clearance in patients with bronchiectasis. (1992) (53)
New insights into airway inflammation by endobronchial biopsy. (1992) (53)
Reducing agents inhibit rhinovirus‐induced up‐regulation of the rhinovirus receptor intercellular adhesion molecule‐1 (ICAM‐1) in respiratory epithelial cells (2002) (53)
The inflammatory basis of asthma and its implications for drug treatment (1996) (53)
Human bronchial fibroblasts express the 5-lipoxygenase pathway (2006) (53)
New strategies with anti-IgE in allergic diseases (2014) (52)
15-lipoxygenase immunoreactivity in normal and in asthmatic airways. (1995) (52)
Early changes in T lymphocytes recovered by bronchoalveolar lavage after local allergen challenge of asthmatic airways. (1992) (52)
Effect of selective phosphodiesterase 3 inhibition on the early and late asthmatic responses to inhaled allergen. (1998) (52)
Episodes of respiratory morbidity in children with cough and wheeze. (1994) (52)
Rhinoviruses in the pathogenesis of asthma: the bronchial epithelium as a major disease target. (2006) (52)
Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: relevance of circulating basophils to measurements of plasma histamine. (1984) (52)
The mast cell (1992) (51)
Airway inflammation and remodeling in asthma: Current concepts (2002) (51)
Mast cell distribution and neutral protease expression in acute and chronic allergic conjunctivitis (1995) (51)
Prevalence of untreated asthma in a population sample of 6000 older adults in Bristol, UK (2001) (51)
Analysis of Ig VH region genes encoding IgE antibodies in splenic B lymphocytes of a patient with asthma. (1995) (51)
3',5'-Cyclic adenosine monophosphate-dependent protein kinase of the rat serosal mast cell and its immunologic activation. (1980) (51)
Pattern of usage and somatic hypermutation in the VH5 gene segments of a patient with asthma: Implications for IgE (1997) (51)
Assessment of deposition of inhaled aerosol in the respiratory tract of man using three-dimensional multimodality imaging and mathematical modeling. (1996) (50)
Staphylococcus aureus and its IgE-inducing enterotoxins in asthma: current knowledge (2020) (50)
The effects of theophylline on mucosal inflammation in asthmatic airways: biopsy results. (1995) (50)
Differential inhibitory effect of regular inhaled corticosteroid on airway responsiveness to adenosine 5′ monophosphate, methacholine, and bradykinin in symptomatic children with recurrent wheeze (1997) (50)
The Mast Cell as a Source of Cytokines in Asthma (1996) (50)
Inflammatory and T-cell profile of asthmatic airways 6 hours after local allergen provocation. (1996) (50)
NF-kappa B and TNF-alpha: a positive autocrine loop in human lung mast cells? (2002) (49)
Has the time come to rethink the pathogenesis of asthma? (2010) (49)
Epidemiology of Viral Respiratory Tract Infections (1996) (49)
The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma. (1989) (49)
The relationship between mast cell-mediator release and bronchial reactivity in allergic asthma. (1987) (49)
The inhibitory effect of terfenadine and flurbiprofen on early and late‐phase bronchoconstriction following allergen challenge in atopic asthma (1990) (49)
Ozone-induced lung function decrements do not correlate with early airway inflammatory or antioxidant responses (1999) (49)
Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function. (2005) (49)
Adenosine receptors as promising therapeutic targets for drug development in chronic airway inflammation. (2006) (49)
Cytokine production by human mast cells. (1995) (49)
Asthma mechanisms, determinants of severity and treatment: the role of nedocromil sodium Report of a workshop held in Whistler, British Columbia, Canada, 18–19 May 1995 (1995) (49)
Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblasts. (2007) (49)
Airway inflammation and remodeling in asthma : current concepts. (2001) (48)
Inhaled PAF fails to induce airway hyperresponsiveness to methacholine in normal human subjects. (1990) (48)
The role of LTA4H and ALOX5AP polymorphism in asthma and allergy susceptibility (2008) (48)
Hypocapnia and asthma: a mechanism for breathing retraining? (2005) (48)
Identification of novel expressed sequences, up‐regulated in the leucocytes of chronic fatigue syndrome patients (2003) (48)
Peak expiratory flow changes during experimental rhinovirus infection. (2000) (48)
Descriptive study of cough, wheeze and school absence in childhood. (1996) (47)
Experimental rhinovirus infection in volunteers. (1996) (47)
Recent advances in understanding the pathogenesis of asthma and its clinical implications. (1988) (47)
The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma. (1988) (47)
Antileukotriene therapy. Future directions. (2000) (47)
Immunohistochemical analysis of nasal biopsies during rhinovirus experimental colds. (1994) (47)
Nedocromil sodium is more potent than sodium cromoglycate against AMP‐induced bronchoconstriction in atopic asthmatic subjects (1989) (47)
Novel targets of therapy in asthma (2009) (47)
Asthma and allergy--disorders of civilization? (1998) (47)
Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial). (2000) (46)
Comparative nasal effects of bradykinin, kallidin and [Des‐Arg9]‐bradykinin in atopic rhinitic and normal volunteers. (1991) (46)
Bronchoconstriction induced by ipratropium bromide in asthma: relation to hypotonicity. (1984) (46)
Respiratory involvement in systemic lupus erythematosus. A clinical and immunological study. (1976) (46)
Multiple cytokine mRNA expression in human mast cells stimulated via Fc epsilon RI. (1995) (46)
Histochemical heterogeneity of human mast cells: disease-related differences in mast cell subsets recovered by bronchoalveolar lavage. (1990) (46)
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma (1990) (45)
ADAM33: a newly identified protease involved in airway remodelling. (2006) (45)
Genetic susceptibility to the respiratory effects of air pollution. (2009) (45)
Stratified approaches to the treatment of asthma (2013) (45)
An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. (2016) (45)
The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations. (1992) (45)
Distribution and determinants of personal exposure to nitrogen dioxide in school children. (1996) (44)
Airway refractoriness to adenosine 5'-monophosphate after repeated inhalation. (1989) (44)
Airway response to exercise and methacholine in children with respiratory symptoms. (1991) (44)
The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation (2009) (44)
Using genetics to predict the natural history of asthma? (2010) (44)
The acetaminophen enigma in asthma. (2011) (44)
Histamine and its antagonists in asthma. (1989) (44)
Role of mast cells and basophils in asthma. (1995) (44)
Repeated inhalation of bradykinin attenuates adenosine 5'-monophosphate (AMP) induced bronchoconstriction in asthmatic airways. (1992) (43)
Epithelially derived endothelin and nitric oxide in asthma. (1995) (43)
Nasal cavity lining fluid ascorbic acid concentration increases in healthy human volunteers following short term exposure to diesel exhaust. (1998) (43)
Comparison of the prevalence of asthma among Asian and European children in Southampton. (1992) (43)
Immunohistochemical analysis of the activation of NF‐κB and expression of associated cytokines and adhesion molecules in human models of allergic inflammation (1999) (43)
Trials and tribulations in identifying new biologic treatments for asthma. (2012) (42)
Evaluation of the accuracy and precision of lung aerosol deposition measurements from single-photon emission computed tomography using simulation. (2000) (42)
The protective effects of intravenous theophylline and enprofylline against histamine- and adenosine 5'-monophosphate-provoked bronchoconstriction: implications for the mechanisms of action of xanthine derivatives in asthma. (1989) (42)
Airway and cardiovascular responses to inhaled prostacyclin in normal and asthmatic subjects. (2015) (42)
Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers. (1999) (42)
Profile of bronchial responsiveness in children with respiratory symptoms. (1992) (42)
Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis (2004) (42)
Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments (2006) (42)
Amino acid residues that influence Fc epsilon RI-mediated effector functions of human immunoglobulin E. (1998) (42)
Mast cell-dependent inflammatory mediators and their putative role in bronchial asthma. (1985) (42)
Mucosal inflammation in severe glucocorticoid-dependent asthma. (1999) (42)
HLA genetics and allergic disease. (1995) (42)
Relationship between skin‐prick tests, the multiple allergosorbent test and symptoms of allergic disease (1989) (42)
Matrix metalloproteinase‐2 from bronchial epithelial cells induces the proliferation of subepithelial fibroblasts (2002) (42)
Nasal effects of bradykinin and capsaicin: influence on plasma protein leakage and role of sensory neurons. (1992) (41)
Human lung mast cells are enriched in the capacity to produce granulocyte‐macrophage colony‐stimulating factor in response to IgE‐dependent stimulation (1998) (41)
Prophylactic management of children at risk for recurrent upper respiratory infections: the Preventia I Study (2004) (41)
Contribution of Bronchial Fibroblasts to the Antiviral Response in Asthma1 (2009) (41)
Adenosine provocation: a new test for allergic type airway inflammation. (2002) (41)
Symptoms, atopy, and bronchial response to methacholine in parents with asthma and their children. (1987) (41)
Lower airways inflammatory response during rhinovirus colds. (1995) (41)
Expression of the high-affinity IgE receptor on peripheral blood dendritic cells: differential binding of IgE in atopic asthma. (2001) (41)
The distribution of adhesive mechanisms in the normal bronchial epithelium. (1993) (41)
Release of adenosine and its metabolites from activated human leucocytes. (1986) (40)
Inflammatory and structural changes in the airways of patients with asthma. (2000) (40)
Lack of evidence of a significant association between HLA‐DR, DQ and DP genotypes and atopy in families with HDM allergy (1996) (40)
Review of the UK air quality index (2011) (40)
Inhibition by nedocromil sodium of early and late phase bronchoconstriction and airway cellular infiltration provoked by ovalbumin inhalation in conscious sensitized guinea‐pigs (1988) (40)
Dendritic cells in normal and asthmatic airways: expression of the alpha subunit of the high affinity immunoglobulin E receptor (Fc epsilon RI -alpha). (1996) (40)
Pulmonary synthesis, release, and metabolism of prostaglandins. (1985) (40)
Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma. (2005) (39)
The role of IgE in allergen‐induced inflammation and the potential for intervention with a humanized monoclonal anti‐IgE antibody (2001) (39)
Personal exposures of children to nitrogen dioxide relative to concentrations in outdoor air (2000) (39)
Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma. (1986) (39)
Effects of prostaglandin D2 on rat serosal mast cells: discordance between immunologic mediator release and cyclic AMP levels. (1980) (39)
Effect of 15-(s)-hydroxyeicosatetraenoic acid on allergen-induced asthmatic responses. (1990) (39)
The role of ADAM33 in the pathogenesis of asthma (2004) (39)
A Technique for Simulating Radionuclide Images from the Aerosol Deposition Pattern in the Airway Tree (1997) (38)
Cholinergic-Mediated Bronchoconstriction Induced by Prostaglandin D2, Its Initial Metabolite 9α, 11β-PGF2, and PGF2α in Asthma (1987) (38)
The IgE- and calcium-dependent release of eicosanoids and histamine from human purified cutaneous mast cells. (1989) (38)
Preferential generation of prostaglandin D2 by rat and human mast cells. (1981) (38)
Anti‐IgE treatment: an update (2001) (37)
Bronchial epithelial shedding in asthmatics and non-asthmatics. (1993) (37)
Omalizumab, a novel anti-IgE therapy in allergic disorders (2001) (37)
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This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnostics (2013) (23)
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A randomised controlled study of the effectiveness of breathing retraining exercises taught by a physiotherapist either by instructional DVD or in face-to-face sessions in the management of asthma in adults. (2017) (12)
Beta-catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells. (2005) (12)
Acute effect of inhaled bradykinin on tracheobronchial clearance in normal humans. (1992) (12)
Critical success factors of an effective repairs and maintenance service for social housing in the UK (2014) (12)
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation. (1986) (12)
The role of anti-IgE therapies in the treatment of asthma. (2002) (12)
The protective efficacy of inhaled, oral and intravenous nedocromil sodium against adenosine-5'-monophosphate-induced bronchoconstriction in asthmatic volunteers. (1990) (12)
New strategies in the treatment and prevention of allergic diseases (2004) (12)
The European Respiratory Society plans its future: the 2013–2018 strategic plan (2014) (12)
Effect of azelastine and ketotifen on the bronchial and skin responses to platelet‐activating factor in humans (1991) (12)
The pulmonary deposition of two aerosol preparations of nedocromil sodium delivered by MDI assessed by single photon emission computed tomography. (1996) (12)
Inhaled loop diuretics and basal airway responsiveness in man: evidence of a role for cyclo-oxygenase products. (1995) (12)
Are marine environmental pollutants influencing global patterns of human disease? (2013) (12)
Mediators of Inflammation in Response to Air Pollution: A Focus on Ozone and Nitrogen Dioxide (1996) (12)
Immune circuits in asthma. (2013) (12)
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha. (1990) (12)
The efficacy and therapeutic position of nedocromil sodium. (1996) (12)
Polymorphism at the tumour necrosis factor locus and asthma. (1996) (12)
β-Catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells (2005) (12)
Prevention of allergy and asthma: interim report. (2000) (12)
WAO International Scientific Conference (WISC 2016) Abstracts (2017) (12)
Inflammatory cells and their mediators in the pathogenesis of asthma. (1988) (12)
Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus (2017) (12)
Allergy Frontiers: Classification and Pathomechanisms (2009) (12)
Medium-term culture of normal human oral mucosa: a novel three-dimensional model to study the effectiveness of drugs administration. (2012) (12)
Asthma survey items as predictors of respiratory problems in children 2 yrs later: a longitudinal study. (1999) (11)
The inside story: Health effects of indoor air quality on children and young people (2020) (11)
Lessons learnt from the epidemic of asthma. (2004) (11)
Evaluating the long-term consequences of air pollution in early life: geographical correlations between coal consumption in 1951/1952 and current mortality in England and Wales (2018) (11)
Acute inflammatory responses in the airways and peripheral blood following short-term exposure to diesel exhaust in healthy human subjects. (1999) (11)
The Role of Adenosine in Respiratory Physiology (1990) (11)
Evidence against the formation of 13,14‐dihydro‐15‐keto‐prostaglandin F2α following inhalation of prostaglandin D2 in man (1986) (11)
Smoking habits in a cohort of U.K. adolescents. (2000) (11)
The influence of terfenadine and ipratropium bromide alone and in combination on bradykinin‐induced nasal symptoms and plasma protein leakage (1992) (11)
Genetics of Asthma (1993) (11)
The Hereditary Basis of Allergic Diseases (2002) (11)
Manchester asthma and allergy study: Polymorphisms in ADAM33 predict lung function at age 5 years (2004) (11)
The need for a pathological classification of asthma. (1991) (11)
The effect of methyltransferase inhibitors on histamine release from human dispersed lung mast cells activated with anti-human IgE and calcium ionophore A23187. (1984) (11)
Weaning Adults from Mechanical Ventilation (1999) (11)
A treatment for allergic rhinitis:a view on the role of levocetirizine (2005) (11)
Inspiratory Muscle Dysfunction after Prolonged Periods of Mechanical Ventilation (2002) (11)
Skin responses to bradykinin, kallidin, and [desArg9]-bradykinin in nonatopic and atopic volunteers. (1993) (11)
6,9‐deepoxy‐6,9‐(phenylimino)‐Δ6,8‐Prostaglandin I1, (U‐60, 257) stimulates prostaglandin D2 and inhibits thromboxane B2 release from ionophore challenged human dispersed lung cells (1984) (11)
Cyclosporin A treatment and airways inflammation in corticosteroid‐dependent asthma (1998) (11)
Allergic bronchopulmonary aspergillosis and hypersensitivity pneumonitis (2013) (11)
Adenosine: a key effector molecule of asthma or just another mediator? (2002) (11)
The role of cytokines in the pathogenesis of allergic asthma. (1993) (11)
Augmentation of permeability in the bronchial epithelium by the dust mite allergen Der p1 (1995) (10)
Chronic inflammation in asthma (1998) (10)
Asthma: a diagnostic and therapeutic challenge. (1991) (10)
The Effect of Inhaled Adenosine 5′-Monophosphate (AMP) on Airway Calibre in Normal and Asthmatic Subjects (1986) (10)
A comparison of the effects of polyarginine and stimulated eosinophils on the responsiveness of the bovine isovolumic bronchial segment preparation (1993) (10)
Asthma: past, present and future (2012) (10)
Efficacy/safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial (2010) (10)
Air pollution and lung health: An epilogue (2013) (10)
The era of research collaborations: new models for working together (2017) (10)
Immunogenetics of human IgE. (1996) (10)
Epidemiology of rhinitis and asthma (1997) (10)
Susceptibility genes in severe asthma (2006) (10)
Allergy Frontiers: Diagnosis and Health Economics (2009) (10)
The clear and persistent impact of air pollution on chronic respiratory diseases: a call for interventions (2021) (10)
Clinical pharmacology of asthma. Implications for treatment. (1993) (10)
Reflections by the Chairman (1991) (10)
The release and role of inflammatory mediators in asthma. (1985) (10)
Inhibition of exercise-induced asthma by nifedipine: a dose-response study. (1987) (9)
Overcoming fragmentation of health research in Europe: lessons from COVID-19 (2020) (9)
Improving outcomes for asthma patients with allergic rhinitis: the MetaForum conferences (2006) (9)
Mechanisms and significance of adenosine‐induced bronchoconstriction in asthma (1987) (9)
Controlled-Release Theophylline in the Treatment of Nocturnal Asthma (1990) (9)
Air pollution—a wicked problem (2017) (9)
Antihistamines in the treatment of asthma (1994) (9)
Mucosal cytokine expression in allergic rhinitis. (1995) (9)
The future of lung research in the UK (2007) (9)
Bronchial mucosal mast cells and their implications in the pathogenesis of asthma. (1986) (9)
Health Effects of Indoor Air Quality on Children and Young People (2020) (9)
Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects. (1991) (9)
The Future of Asthma Care: Personalized Asthma Treatment. (2019) (9)
Temporal association between pulmonary inflammation and antioxidant induction following hyperoxic exposure of the preterm guinea pig. (1993) (9)
Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets. (2012) (9)
Persistent airway T-lymphocyte activation in chronic corticosteroid-treated symptomatic asthma. (2000) (9)
Glucocorticoids enhance IgE synthesis. Are we heading towards new paradigms? (2000) (8)
The role of leukotrienes and prostaglandins in asthma: evidence from clinical investigations. (1990) (8)
Attenuation of exercise induced asthma by local hyperthermia. (1992) (8)
Regulatory and research needs. (2013) (8)
Cohabiting with domestic mites. (1993) (8)
FIBROBLASTS AND THE EXTRACELLULAR MATRIX IN ASTHMA (1998) (8)
Mechanisms of purine-induced bronchoconstriction in asthma. (1990) (8)
INTRAVENOUS PREDNISOLONE IN ASTHMA (1976) (8)
The Epithelial-Mesenchymal Trophic Unit in Asthma (2000) (8)
Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy. (2007) (8)
Biomarkers of asthma (1998) (8)
Stimulation of human airway epithelial cells by platelet activating factor (PAF) and arachidonic acid produces 15-hydroxyeicosatetraenoic acid (15-HETE) capable of contracting bronchial smooth muscle. (1992) (8)
HOUSE-DUST MITE ALLERGEN AND ASTHMA. AUTHOR'S REPLY (1991) (8)
Assessment and treatment of obstructive airways disease in the elderly. (1990) (8)
Tumour necrosis factor-α as a therapeutic target in asthma (2006) (8)
Human mast cell tryptase: a biochemical marker for mast cell degranulation (1989) (8)
The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways. (1989) (8)
Adenosine as a Putative Mediator in Asthma: Its Role in Bronchoconstriction and Modulation of Histamine Release from Human Lung Mast Cells and Basophil Leucocytes (1985) (8)
Davos declaration: Allergy as a global problem (Allergy: European Journal of Allergy and Clinical Immunology (2012) 67, (141-143)) (2012) (8)
Does inhaled PAF cause airway hyperresponsiveness in humans? (1990) (8)
Evidence for and against chromosome 5q as a region of interest in asthma and atopy (1996) (8)
Factors determining bradykinin bronchial responsiveness and refractoriness in asthma. (1993) (8)
Wheal-and-flare responses to intradermally injected adenosine 5'-monophosphate, hypertonic saline, and histamine: comparison of atopic and nonatopic subjects. (1989) (8)
Cellular and biochemical events in the pathogenesis of asthma. (1986) (8)
What does inflammation and airway remodelling mean (2001) (7)
Anti-IgE Therapy in Asthma and Allergy (2001) (7)
Changing attitudes to exercise induced asthma. (1983) (7)
The influence of the long acting beta agonist salmeterol xinafoate on t lymphocyte lavage populations and activation status in asthma (1992) (7)
T cell receptor (TCR) Vbeta gene usage in bronchoalveolar lavage and peripheral blood T cells from asthmatic and normal subjects. (1998) (7)
The molecular and cell biology of allergy (1998) (7)
Perspective: A human touch (2011) (7)
Is big beautiful? The continuing story of ADAM33 and asthma (2005) (7)
The current state of respiratory research in the UK (2015) (7)
Control of mediator release from mast cells (1982) (7)
The effect of inhaled allergen on circulating basophils in atopic asthma. (1992) (7)
Skin Prick Testing in Clinical Practice (2000) (7)
Application of functional genomics to study of inflammatory airways disease (1999) (7)
Nitric oxide synthase in asthmatic human lung (1993) (7)
Recent Developments in the Pathogenesis and Epidemiological Trends of Asthma (1999) (7)
Inflammatory mediators and cellular infiltration of the lungs in a guinea pig model of the late asthmatic reaction (2007) (7)
Effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid on tracheobronchial clearance in normal human airways. (1991) (7)
Middleton's allergy essentials (2016) (7)
Increased sensitivity to the consequences of rhinoviral infection in atopic subjects. (1995) (7)
A disintegrin and metalloprotease 33 expression in asthmatic airways and human embryonic lungs (2005) (7)
Reducing the hidden burden of severe asthma: recognition and referrals from primary practice (2020) (7)
Treating hay fever. (1985) (7)
Inflammation and allergy drug design (2011) (7)
The acute exacerbation of asthma: Pathogenesis (1999) (7)
135 The effect of inhaled beclomethasone dipropionate (BDP) on inflammatory cells in the asthmatic airways (1991) (7)
Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development (2009) (7)
Inflammatory Processes in Bronchial Asthma (2012) (7)
Asthma diagnosis: addressing the challenges. (2015) (7)
Dexamethasone treatment fails to reduce oxygen-induced lung injury in the preterm guinea pig. Effects on pulmonary inflammation and antioxidant status. (1993) (7)
Disabling inflammatory pathways with biologics and resulting clinical outcomes in severe asthma (2013) (7)
Human leukocyte antigen genes and allergic disease. (1996) (6)
The use and misuse of domiciliary nebulizer therapy on the Isle of Wight. (1989) (6)
Luminal mast cells of the human respiratory tract (1986) (6)
The inflammatory response in asthma. (1991) (6)
Activation of human mast cells after immunoglobulin E-dependent and neuropeptide stimulation. (1989) (6)
The role of inflammation in airways disease (1991) (6)
Experimental models in asthma (1999) (6)
Identification and possible functions of ADAM33 as an asthma susceptibility gene (2004) (6)
Genetic common ground between allergic and autoimmune disease: The role of cytotoxic T-lymphocyte antigen 4. (2004) (6)
Anticholinergics in acute bronchial asthma. (1987) (6)
ASTHMA THERAPY — PRESENT ANXIETIES AND FUTURE RESEARCH (1992) (6)
Allergy Frontiers:Clinical Manifestations (2009) (6)
Mediator Release from Human Lung Mast Cells (1985) (6)
New insights into asthma pathogenesis (2002) (6)
Dose-response relationship of the H1-histamine antagonist, ebastine, against histamine and methacholine-induced bronchoconstriction in patients with asthma (1990) (6)
CYCLO-OXYGENASE. AUTHOR'S REPLY (1998) (6)
The atopy phenotype revisited (2004) (6)
Therapeutic options for persistent asthma. (2001) (6)
Ionophore-dependent generation of eicosanoids in human dispersed lung cells. Modulation by 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin I1 (U-60,257). (1986) (6)
Inhaled sodium cromoglycate in young children with moderate asthma (1998) (6)
Immunopharmacology of Mast Cells (1989) (6)
BENZALKONIUM CHLORIDE AND BRONCHOCONSTRICTION (1986) (6)
Document de consensus WAO–ARIA–GA2LEN sur le diagnostic allergologique moléculaire ☆ (2015) (6)
Effect of inhaled bradykinin on indices of airway responsiveness in asthmatic subjects. (1994) (6)
The immunoglobulin E- and calcium-dependent release of histamine and eicosanoids from human dispersed mastocytosis spleen cells. (1988) (6)
Rhinovirus is not detectable in peripheral lung tissue after asthma death (2003) (6)
The Effect of Inhaled LY-170680 on Leukotriene D4-Induced Bronchoconstriction in Healthy Volunteers (1991) (5)
Tumor necrosis factor-α in severe corticosteroid-refractory asthma (2007) (5)
AIRWAY INFLAMMATION AND REMODELLING IN ASTHMA – CAUSE AND EFFECT ? (5)
Modulation of arachidonic acid metabolism in dispersed human lung cells by the inhibitor of leukotriene formation U-60, 257 (piriprost) (1984) (5)
Effects of prostaglandin D2 and theophylline on rat serosal mast cells: discordance between increased cellular levels of cyclic AMP and activation of cyclic AMP-dependent protein kinase. (1981) (5)
The effect of respiratory manoeuvres and pharmacological agents on the pharmacokinetics of nedocromil sodium after inhalation. (1992) (5)
Asthma: clinical aspects and mucosal immunology (2005) (5)
Mast cell tryptase as a proinflammatory mediator in late-phase asthmatic response (2002) (5)
Epithelial repair is inhibited by an α1,6-fucose binding lectin (2007) (5)
98 – The Chromones: Cromolyn Sodium and Nedocromil Sodium (2014) (5)
285 Bronchial mucosal intercellular adhesion molecule-1 [ICAM-1] and endothelial leukocyte adhesion molecule-1 [ELAM-1] expression in normals and asthmatics (1991) (5)
Reversibility of the allergen‐provoked late asthmatic response by an inhaled β2‐adrenoceptor agonist (1994) (5)
The role of theophylline in the management of chronic asthma in adults (1996) (5)
290 Role of histamine and prostaglandins in EIA (1988) (5)
Therapy and prevention (2010) (5)
The mediator and cellular basis of the allergic response (1988) (5)
Mast cell and eosinophil proteases in the chronic allergic inflammatory response (1998) (5)
Differences in the Asthma Treatment of Children Between Europe and Japan: A Questionnaire-Based Survey Using Model Cases (2009) (5)
Comparative vascular effects of histamine, prostaglandin (PG) D2 and its metabolite 9 alpha,11 beta-PGF2 in human skin. (1988) (5)
Inhaled sodium cromoglycate in children with asthma (2002) (5)
Association of the Gln 27 beta 2-adrenoceptor polymorphism and IgE variability in asthmatic families. (1997) (5)
Anaphylactic Release of Prostaglandins from Dispersed Human Lung Cells (1983) (5)
A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood (2019) (5)
Allergy Frontiers: Therapy and Prevention (2010) (5)
A non-bronchoconstrictor, bacteriostatic preservative for nebuliser solutions. (1991) (5)
Cross refractoriness between bradykinin and hypertonic saline challenges in asthma. (1995) (5)
Effect of inhaled platelet-activating factor on bronchial inflammation in atopic non-asthmatic subjects. (1992) (5)
Adenosine in asthmatic lung. (1988) (5)
A need for circulating biomarkers of severe persistent asthma and its treatment (2006) (5)
Aetiology of asthma: how public health and molecular medicine work together (1996) (4)
Epithelial repair is inhibited by an alpha(1,6)-fucose binding lectin. (2007) (4)
The Genetics of Asthma: Towards a Personalised Approach to Diagnosis and Treatment (2014) (4)
Pharmacogenetics: the new science of personalizing treatment. (2004) (4)
The Link Between Asthma and COPD. Foreword, summary and conclusions. (1999) (4)
Text of Plenary Lecture Given by S.T. Holgate (1994) (4)
Theophylline at Therapeutic Concentrations Inhibits NF-κB Activation in Human Lung Mast Cells (2001) (4)
Newer therapies for asthma: a focus on anti-IgE. (2002) (4)
Maintenance of Skills, Competencies, and Performance in Allergy and Clinical Immunology: Time to Lay the Foundation for a Universal Approach (2012) (4)
What's new about hay fever? (1985) (4)
Genetic linkage analysis of atopic disease (1994) (4)
IgE-dependent activation of human lung mast cells is not associated with increased phospholipid methylation. (1988) (4)
Chapter 11 – Theophylline (1984) (4)
EXERCISE, ASTHMA, AND MAST CELLS (1983) (4)
Universal declaration on the human genome and human rights (revised draft). (1997) (4)
The trials and tribulations of anti–IL-5 … (2002) (4)
Education and adherence to therapy in a clinical setting (1998) (4)
The history of leukotrienes and leukotriene modifying drugs (2001) (4)
Multi-Modality Imaging: The Use of Single Photon Emission Computed Tomography and Magnetic Resonance Imaging to Assess Regional Intra-Pulmonary Deposition of Nebulised Aerosols (1995) (4)
Anti-inflammatory strategies for the treatment of asthma. (1992) (4)
Allergy : an atlas of investigation and management (2005) (4)
Chapter 14 – The Genetic Basis of Allergic Disease (2006) (4)
Genetics of Asthma: What's New? (2008) (4)
Chapter 7 – Asthma (2017) (4)
Allergy Frontiers: Future Perspectives (2010) (4)
The contribution of inflammatory cells to the pathogenesis of asthma (1991) (4)
The pathophysiology of bronchial asthma and targets for its drug treatment (1986) (4)
The management of paediatric allergy: not everybody's cup of tea – 10–11th February 2012 (2013) (3)
The SPDEF Network Regulates Mucus Cell Differentiation In Asthma (2011) (3)
The generation of prostaglandins by human lung and their effects on airway function in man. (1986) (3)
Identification and Function of a Novel Candidate Gene for Asthma:ADAM 33 (2005) (3)
The subcellular localisation of interleukin 4 in the respiratory mucosa using immunoelectron microscopy (1994) (3)
Seasonal distribution of episodes of acute severe asthma in adults (1997) (3)
Introduction to Fulda Asthma Genetics Supplement of Clinical and Experimental Allergy (1999) (3)
Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma. (1993) (3)
Is Artificial Fluoride Absorbed to the Same Extent as Natural Fluoride? (2008) (3)
Airway Remodeling and Repair (1998) (3)
The European Respiratory Society fellowship programme: supporting young careers and building networks (2013) (3)
Considerations on third generation antihistamines (2002) (3)
The importance of primary care research in the management of respiratory disease. (2012) (3)
Pathophysiology and clinical aspects of respiratory allergies with reference to asthma (2000) (3)
Asthma. The mast cell. (1992) (3)
Inhaled histamine increases the rate of absorption of sodium cromoglycate from the lung. (1992) (3)
Mast Cell Activation and Secretion (1981) (3)
263 Neutrophils do not participate in the development of the late asthmatic reaction (LAR) in guinea-pigs (1988) (3)
Air pollution: The time has arrived for the medical profession to take ownership of the problem and act (2019) (3)
ADENOSINE : ITS CONTRIBUTION TO OUR UNDERSTANDING OF ASTHMA (1998) (3)
Asthma: basis and management at different ages. (1995) (3)
Inhaled corticosteroid dose-reducing effect of omalizumab in patients with controlled, severe asthma according to usage of inhaled long-acting beta-agonists (2002) (3)
Peripheral Blood Cd4 T Cell Type 1 and Type 2 Cytokine Production in Atopic Asthmatic and Normal Subjects (3)
The Influence of Resting Airway Calibre on Non-Specific and Specific Airway Reactivity in Asthma (1984) (3)
Arrythmogenic Right Ventricular Dysplasia (2016) (3)
44 – Mucosal Immune Function in Asthma (1994) (3)
Opposite effects of inhaled bradykinin and [desArg9]-bradykinin on tracheobronchial clearance in normal humans. (1996) (3)
Genetic influences on Asthma Severity. (2001) (3)
Fast Facts: Asthma (2006) (3)
Chapter 7 – Airway Remodeling (2002) (3)
The effect of omalizumab on lung function in adolescents with moderate to severe allergic asthma (2018) (3)
515 Mediator release from human skin mast cells activated by IgE-dependent and non-immunological stimuli (1988) (3)
Candidate loci and random marker approaches to studying the genetics of asthma. (1996) (3)
Low Concentrations of Diesel Exhaust Induce a Neutrophilic Response and Upregulate IL-8 mRNA in Healthy Subjects but Not in Asthmatic Volunteers (2001) (3)
Report of a workshop assessing the risks and benefits of inhaled anti-inflammatory treatment for asthma. (1994) (3)
The European Respiratory Society evaluates its 2013–2018 strategic plan implementation (2016) (2)
The ever-expanding ERS fellowship programmes: achievements over the past 3 years (2016) (2)
Breathing exercises for asthma - results of the BREATHE study (2017) (2)
Interfaces in Medicine: Asthma (1990) (2)
Asthma mechanisms, determinants of severity and treatment (1996) (2)
Effect of Nedocromil Sodium on Early and Late Phase Responses to Allergen Challenge in the Guinea-Pig (2012) (2)
Up-regulation of epithelial and fibroblast prostaglandin D2 CRTH2-receptors in asthma (2007) (2)
Comparison of SPECT data on regional aerosol deposition with empirical modeling (2001) (2)
Recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma (2012) (2)
SPRINTER: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Determine the Efficacy and Safety of Inhaled Interferon Beta-1a (SNG001) for the Treatment of Patients Hospitalized Due to COVID-19 (NCT04732949) (2022) (2)
667 Characterisation of the T-cell population of the normal lung (1991) (2)
Adenosine-Induced Bronchoconstriction in Asthma and Its Antagonism by Theophylline (1985) (2)
Genetic analysis of IgE. (1996) (2)
Antihistamines: back to the future. Summary of the conclusions. BSACI. British Society for Allergy and Clinical Immunology. (1999) (2)
[The response of the airways in asthmatic patients to kinin inhalations define a type-B2 receptor profile]. (1992) (2)
Landmark Papers in Allergy (2013) (2)
The Influence of Non-Specific Airway Reactivity on the Immediate Bronchoconstrictor Response to Exercise and Antigen in Asthma (1984) (2)
Lung inflammatory responses in T cell receptor transgenic mice (1997) (2)
Clinical and biochemical aspects of "aspirin-sensitivity". (1986) (2)
Leukotrienes in cardiovascular and pulmonary function (1987) (2)
Improving outcomes for asthma patients with allergic rhinitis: conclusions from the MetaForum conferences (2006) (2)
Validation of endobronchial biopsy specimens for nerve quantitation by computer‐assisted image analysis (2000) (2)
304 The nasal effects of bradykinin (B) and capsaicin (C): Role of “C” sensory nerve fibres (1991) (2)
11. The assessment of deposition of two types of nebulized aerosols in the lung via the use of single photon emission computed tomography and magnetic resonance imaging (1994) (2)
The reliability of a new measure of inspiratory muscle function in patients with COPD (2001) (2)
Chronic mucosal inflammation (1998) (2)
Enhanced airway sensory nerve reactivity in non-eosinophilic asthma (2021) (2)
250 Airways refractoriness after repeated inhalation of adenosine 5′ monophosphate in atopic subjects (1988) (2)
Antihistamines: back to the future. Preface. (1999) (2)
Expert Elicitation on Health Effects Related to Exposure to Ultrafine Particles: Likelihood of Causality and Causal Pathways (2009) (2)
The genetics of allergy and asthma: concluding comments (1995) (2)
301 Mast cell activation in atopic and intrinsic asthma (1991) (2)
Immunohistochemical Analysis of Adhesion Molecules in Airway Biopsies (2000) (2)
The role of neutrophils and eosinophils in a model of asthma in the guinea pig (1990) (2)
Mechanisms of Allergic Airway Disease (1997) (2)
Shared Care For Asthma (1997) (2)
Asthma, physiology, immunopharmacology, and treatment : fourth international symposium (1993) (2)
Chronicity and progression of asthma (1998) (2)
Cellular changes 24 hours after endobronchial allergen challenge in asthma. (1995) (2)
Report of the meeting on ‘The Role of Inflammatory Processes in Airway Hyperresponsiveness’, Boca Raton, Florida, U.S.A., 3‐5 November 1988 (1989) (2)
Lifestyle and indoor air pollution: Allergens (2002) (2)
Inflammation: Rhinitis and asthma (1997) (2)
Chapter 96 – Asthma: Clinical Aspects and Mucosal Immunology (2015) (2)
Lessons to be learned from sodium cromoglycate and related drugs (1993) (2)
A comment on “Scientometrics in a changing research landscape” (2015) (2)
Potential and novel therapies for asthma. (2000) (2)
The Epithelium and Airway Remodelling (2008) (2)
The role of mast cells in the pathogenesis of asthma. (1985) (2)
The effects of interferon beta on cold-induced asthma exacerbations (2012) (2)
11. The quantitative assessment of pulmonary penetration for aerosol administered by metered dose inhaler using aligned CT and SPECT datasets (1990) (2)
The effects of diesel particulates on normal and asthmatic airways. (2002) (2)
A comparison of the bronchodilator effect of salbutamol inhaled via Turbuhaler as two consecutive doses or as two divided doses at different time intervals. (1999) (2)
The long-acting b2-agonist salmeterol xinafoate: effects on airway inflammation in asthma (1999) (2)
Eosinophils in allergic inflammation and allergic asthma (1993) (2)
A search for biochemical markers of human mast cell activation in vivo. (1987) (2)
Rebuttal from Drs. Wenzel and Holgate (2006) (2)
EPIDEMIOLOGY OF ASTHMA (2000) (2)
Molecular mediators of asthma: current insights. (1996) (2)
Are long-acting beta2-agonists safe in the treatment of asthma? (2008) (2)
Does baseline airway caliber affect measurements of airway responsiveness to histamine. (1993) (2)
Factors Associated with Asthma Mortality: A National United Kingdom Database Analysis (2007) (2)
The Mode of Action of Airway Responses to Adenosine in Asthma (1990) (2)
The temporal relationship between the neural and vascular actions of kallidin within the nose (1993) (2)
Polymorphisms in the Interleukin-4 (IL-4) and in interleukin 4 receptor alpha chain (IL-4Ralpha ) genes confer susceptibility to asthma and atopy in a Caucasian population. (2003) (1)
Adenosine-induced Bronchoconstriction in Asthma (2015) (1)
Clinical Pharmacology of Asthma (1993) (1)
Air pollution: Consequences for cellular redox signaling, antioxidant defenses and disease (2020) (1)
Announcement (1996) (1)
Classification and pathomechanisms (2009) (1)
Red cell magnesium in a population of house dust mite sensitive asthmatics. (2000) (1)
Cellular and Molecular Networks in Clinical Immunology and Allergy: 18th Symposium of the Collegium Internationale Allergologicum, Funchal/Madeira, September 1990 (1991) (1)
Induction of bronchial beta-adrenergic receptor resistance in normal man [proceedings]. (1977) (1)
Defective Epithelial Barrier Function In Asthma (2011) (1)
Effect of inhaled therapeutic interventions on the natural history of asthma (1998) (1)
Accelerating the transition of clinical science to translational medicine. (2021) (1)
[Respiratory inflammation]. (1997) (1)
The epidemic of asthma and allergy (2004) (1)
Anti-Cytokine Therapy for the Treatment of Asthma (2003) (1)
General group discussion (2001) (1)
Effect of an inhaled mast cell stabiliser, N-acetyl-aspartyl-glutamate (Zy15109) on allergen-induced immediate bronchoconstriction. (1989) (1)
Allergy testing in respiratory medicine. (1996) (1)
Contents, Vol. 94, 1991 (1991) (1)
Pumactant abolishes early asthmatic response in patients with allergic asthma (2002) (1)
Chapter 40 – Adenosine-Induced Enhancement of Mast Cell Mediator Release in Asthma and COPD (2000) (1)
Contents, Vol. 94, 1991 (1991) (1)
T-CELL MECHANISMS IN CHRONIC ALLERGIC EYE DISEASE (1994) (1)
286 The interaction of inhaled leukotriene C4 with histamine and prostaglandin D2 on airway calibre in asthma (1988) (1)
Will the Advent of Antileukotriene Therapy Lead to Changes in Asthma Treatment Guidelines? (1997) (1)
Susceptibility Loci Regulating Total Serum IgE Levels , Bronchial Hyperresponsiveness , and Clinical Asthma Map to Chromosome 5 q * (1)
Annual Review of Immunology, Vol. 4, 1986 (1987) (1)
Research collaboration and development of intellectual property with the University of Southampton in the field of asthma and COPD (2006) (1)
50 – Asthma Pathogenesis (2014) (1)
Airway Refractoriness to the Bronchoconstrictor Effect of Inhaled Adenosine 5′ Monophosphate (1987) (1)
UNANSWERED QUESTIONS ON EXACERBATIONS OF ASTHMA AND RHINITIS: A GA 2 LEN WORKSHOP REPORT (2006) (1)
251 Effect of allergen dose augmentation on the development of the late asthmatic response (LAR) (1988) (1)
Today's science – tomorrow's practice: basic mechanisms of allergy and their clinical implications (2002) (1)
From the editors (2008) (1)
Expression of leukocyte adhesion molecules inbronchial biopsies from asthmatic and normal subjects (1993) (1)
A rationale for the use of nedocromil sodium in the treatment of asthma. (1996) (1)
Induction of Regulatory T Cells by Cynodon dactylon-specific allergen immunotherapy (2007) (1)
2 – The genetic basis of allergy and asthma (2012) (1)
P 134 Immunolocalisation of cytokines to human mast cells in conjunctiva from normal seasonal allergic and allergen challenged subjects (1995) (1)
Chapter 23 – Cellular and Mediator Mechanisms of Allergic Inflammation (2006) (1)
Discussion Session A: The early life origins of asthma (1998) (1)
Prevalence of bronchial reactivity to inhaled methacholine in New Zealand children. (1986) (1)
Do leukotrienes fully account for immediate hypersensitivity? (1985) (1)
The management of asthma exacerbations and hospitalizations in young people (1998) (1)
[Genetic factors involved in asthma and atopy. Studies in British families]. (2000) (1)
Airway hyperresponsiveness in offspring from mothers with allergic airway inflammation during pregnancy is muscarinic receptor and ADAM33 dependent (2020) (1)
Insect Venom Allergy (2001) (1)
The Autacoid Functions of Adenosine in Asthma (2020) (1)
Albinism with Hemorrhagic Diathesis and Pigmented Reticuloendothelial Cells (2009) (1)
Role of IgE in Asthma Pathogenesis and Novel Therapeutic Strategies (2002) (1)
361 Influence of salbutamol and sodium cromoglycate on mast cell mediator release in vivo (1985) (1)
Advances in Asthma Management (2012) (1)
Mast cell activation in asthma. (1989) (1)
Comprar Middleton's Allergy Essentials (Online And Print) | Robyn O Hehir | 9780323375795 | Elsevier España (2016) (1)
Efficacy of omalizumab in allergic asthma patients at high-risk for asthma-related death (2002) (1)
Biological Mechanism Associated with Asthma Exacerbation Attack as Revealed By Gene Expression Patterns of Peripheral Blood Mononuclear Cells (2009) (1)
Chapter 2 – Asthma (2006) (1)
Expression of cytokines by mast cells in asthma (1994) (1)
The hygiene hypothesis in the development of atopy and asthma (2000) (1)
The Effects of Intranasal Challenge with Interleukin-8 (IL-8) (1993) (1)
Alternaria Alternata Fungal Allergen Extract Disrupts The Barrier In Differentiated Bronchial Epithelial Cells From Asthmatic Patients (2012) (1)
Andolast, a Novel Calcium-activated Potassium-channel Opener, Inhibits AMP and Exercise Induced Bronchoconstriction in Asthma (2007) (1)
Discovery of new treatments in the context of delivering personalized medicine. (2012) (1)
SULPHUR DIOXIDE, ACID AEROSOLS AND PARTICULATES (1992) (1)
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL EVALUATING THE SAFETY AND EFFICACY OF ETANERCEPT 25 TWICE WEEKLY IN PATIENTS WITH SEVERE PERSISTENT ASTHMA (2007) (1)
Landmark Papers in Allergy: Seminal Papers in Allergy with Expert Commentaries (2013) (1)
Use of the Nijmegen questionnaire to detect hyperventilation in patients with asthma (2005) (1)
Mastcell andhistamine content ofhuman bronchoalveolar lavage fluid (1985) (1)
The mechanisms of intractable asthma (1996) (1)
Mediator andcytokine mechanisms inasthma (1993) (1)
Authors’ response to ‘Critical review of Clara cell protein: sound science?’ (2008) (1)
IgE Regulation: Molecular Mechanisms (1998) (1)
Present and future antiinflammatory strategies for the treatment of asthma (1991) (1)
Anti-IgE antibody for the treatment of allergic asthma (2001) (1)
CHAPTER 37 – Dendritic cells in allergy (2001) (1)
Tapes (1971) (1)
Temporal Relationship between Seasonal Changes in Airway Calibre and Non-Specific Airway Reactivity in Atopic Patients (1985) (1)
Detection of respiratory syncytial virus infection in nasal aspirate samples by flow cytometry (1994) (1)
Rhabdomyolysis cases and acute kidney injury: a 10-year experience at a regional tertiary centre (2020) (1)
Rhabdomyolysis: review of cases over a decade at a regional teaching hospital (2017) (1)
Acute and chronic inflammatory mechanisms in asthma. (1995) (1)
The Incidence of Post-operative Hypoxaemia Following Lobectomy and Pneumonectomy: A pilot study (1994) (1)
Description of pulmonary deposition of radiolabelled aerosol by airway generation using multimodality medical imaging (1995) (1)
Lung deposition of particles in healthy subjects: 3-D radionuclide imaging and numerical model prediction. (1998) (1)
Driving asthma care in Europe: the Brussels Declaration. (2009) (1)
[Not Available]. (1997) (0)
Generation of PGD2 and Release of Granule-associated Mediators by Mast Cells (1981) (0)
Genetics of Asthma and Bronchial Hyperresponsiveness (2009) (0)
ADAM33 in embryonic lungs (2005) (0)
Radionuclide image simulation in the evaluation of accuracy and precision of aerosol deposition measurement by scintigraphy. (1996) (0)
Descriptive study ofcough, wheezeandschool absence inchildhood (2011) (0)
Neuropeptides in endobronchial biopsies from asthmatics (1993) (0)
End tidal CO2 and sensitivity to CO2 measures in patients with asthma versus healthy controls (2005) (0)
PNL2 The Developmental Origins of Asthma (2010) (0)
Middleton's Allergy Essentials: First Edition (2016) (0)
The Long-Term Effects of Bilateral Carotid Endarterectomy (BCE) on Hypoxic Chemosensitivity (1988) (0)
The trials and tribulations of anti-IL-5 em leader. (2002) (0)
Editorial announcement (1985) (0)
Non‐Steroidai Antiinflammatory Drugs in Asthma (2008) (0)
Book Review Clearing the Air: Asthma and indoor air exposures Committee on the Assessment of Asthma and Indoor Air for the Institute of Medicine. 438 pp. Washington, D.C., National Academy Press, 2000. $57.95. 0-309-06496-1 (2000) (0)
S85 Corticosteroid-resistant neutrophilic airway inflammation and hyperresponsiveness caused by il-13 (2017) (0)
99 The airway effects of inhaled tachykinins in non anaesthetized guinea pigs (1988) (0)
Acuteeffect ofinhaled bradykinin on tracheobronchial clearance innormalhumans (1992) (0)
802 T-cell receptor Vβ gene usage in BAL T-cells in health and in asthma (1996) (0)
Session 7. Treatment and prevention of asthma and allergic disorders (2004) (0)
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D<Subscript>2</Subscript>, 9,11-PGF<Subscript>2</Subscript> and PGF<Subscript>2</Subscript> (2004) (0)
Identification and Function of a Novel Candidate Gene for Asthma (2003) (0)
Euro peanRespiratory News (2014) (0)
9a,11fi-Prostaglandin F2, a Novel Metabolite of Prostaglandin D2 Is a Potent Contractile Agonist of Human and Guinea Pig Airways (0)
Contents, Vol. 82, 1987 (1987) (0)
Contents, Vol. 82, 1987 (1987) (0)
Front & Back Matter (2014) (0)
TS3-5 Role of Viruses in the Development of Asthma-The Viral March (2010) (0)
Time-course study of change in sputum cellularity and airway responsiveness to AMP and methacholine after budesonide (2002) (0)
Late-breaking abstract: Airway remodelling induced by ADAM33 is reversible (2014) (0)
CHAPTER 3 – The Genetics of Allergic Disease and Asthma (2010) (0)
Comprar Allergy, 4th Edition Expert Consult Online and Print | Stephen T. Holgate | 9780723436584 | Saunders (2011) (0)
Session 2. Genetic factors and immune tolerance in allergic disorders (2004) (0)
Current Opinion in Allergy and Clinical Immunology: Editorial introductions (2009) (0)
Session 3. Immune cells in allergic disorders (2004) (0)
Mast cell effector mechanisms. Discussion (1996) (0)
The Chemoattractant Properties of Interleukin-4 (1993) (0)
A selfmanagement plan in the treatment of adult asthma Methods SUBJECTS (0)
Infection Of Primary Bronchial Epithelial Cells With Rhinovirus Causes Disruption Of The Epithelial Barrier And DC Activation (2011) (0)
In vitro models of bronchialepithelial cell infection (2007) (0)
Human Blood Eosinophils Translocates 5-Lipoxygenase to the Nucleus 5-Lipoxygenase-Activating Protein and IL-5 Increases Expression of Sampson (1999) (0)
Invited Plenary and Keynote Speakers Abstracts (2007) (0)
Identification of Protocadherin-1 as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness and Asthma. (2009) (0)
Introduction (1995) (0)
Summary and Conclusions (1999) (0)
Summary report from the Pharmacogenetics Working Party Inaugural Meeting, 25 January 2000 (2012) (0)
Deficiency in IFN-γ production during an acute upper respiratory tract infection in atopic asthmatics (1997) (0)
Relationship between chemokines/adhesion molecules expression and allergic inflammatory cells in allergic nasal mucosa (1998) (0)
Does encasing bedding to exclude house dust mites benefit patients with asthma? (2004) (0)
Discussion Session E: Determinants in asthma morbidity (1998) (0)
Front & Back Matter (2016) (0)
Lack of tachyphylaxis to histamine in both moderate and mild asthmatic subjects (1990) (0)
The e ¡ ects of regular inhaled formoterol and budesonide on preformed Th2 cytokines inmild asthmatics (2002) (0)
In Honour of Paul Kallós (1987) (0)
Pharmacological modulation of asthma in relation to mechanisms. (1991) (0)
In Honour of Paul Kallós (1987) (0)
CD 48 on blood leukocytes and in serum of asthma patients varies with severity Short title CD 48 expression varies according to asthma severity Authors (2016) (0)
Ministry of Defence Synopsis of Causation Bronchial Asthma (2008) (0)
Loop in Human Lung Mast Cells? : A Positive Autocrine α B and TNF- κ NF- (2013) (0)
From Molecular Science to the Treatment of Allergy (1999) (0)
Epithelial Cell-Mesenchymal Interaction, Epithelial-Leukocyte Interaction and Epithelial Immune-Response Genes in Allergic Disease (2009) (0)
attacks of asthma . Case-control study of salmeterol and near-fatal (1998) (0)
Eosinophils in a Guinea Pig Model of Allergic Airways Disease (2019) (0)
Chapter 1: Genetic and Environmental Influences (2000) (0)
EVS3-3 Stratified approaches for reclassifying asthma along mechanistic pathways for targeting novel therapies (2012) (0)
VENTILATION DURING MILD SUSTAINED STATIC FOREARM EXERCISE IN MAN (1991) (0)
The Leukotriene Pathway in Human Airway Smooth Muscle Cells (2001) (0)
Genetic and environmental factors in the chronicity of asthma (1998) (0)
Comparison of 3-D SPECT data with model predictions of aerosol deposition in the lung (1996) (0)
Book and Media Reviews (2020) (0)
Th-2 Cytokines Regulate Transforming Growth Factor Alpha (TGFα) and Endothelin (ET-1) Production by Asthmatic Bronchial Epithelial Cells (2002) (0)
Anthony Barrington Kay 1939-2020. (2021) (0)
Interferon-beta antiviral therapy for airway diseases (2005) (0)
A call for more clinical papers (1991) (0)
Molecular mechanisms in allergy and clinical immunology Molecular pathology of allergic airway disease. II: Upper airway disease (2000) (0)
IgE and Anti-IgE Therapy in Allergic Asthma and Rhinitis (2005) (0)
COHABITING WITH DOMESTIC MITES. AUTHOR'S REPLY (1993) (0)
Polarised Release Of Mediators By Differentiated Primary Bronchial Epithelial Cells From Normal And Asthmatic Donors In Response To Grass Pollen (2012) (0)
Immunologic targets for therapeutic interventions (1998) (0)
Studying Innate Interferon Responses to Human Rhinovirus Infection in Cultured Bronchial Epithelial Cells from Asthmatic Children. (2009) (0)
nitrogen dioxide in school children (2005) (0)
Comparison oftheprevalence ofasthma among Asian andEuropean children inSouthampton (1992) (0)
Comprar Allergy Frontiers:Diagnosis and Health Economics | Pawankar, Ruby | 9784431982937 | Springer (2009) (0)
BIOLOGICAL ENDPOINTS TO ASSESS PULMONARY AND CARDIOPULMONARY DAMAGE (2005) (0)
Asthma mechanisms, determinants of severity and treatment. Forward. (1996) (0)
S8-5 The origins and progression of severe asthma (2009) (0)
Introduction (1999) (0)
Comprar Allergy Frontiers: Epigenetics to Future Perspectives · Volume 1 | Pawankar, Ruby | 9784431728016 | Springer (2008) (0)
The Induction Of The SPDEF Network By Rhinovirus Infection Of Primary Bronchial Epithelial Cells From Cystic Fibrosis Patients And Healthy Control Subjects (2012) (0)
LATE-BREAKING ABSTRACT: A 50-year follow-up of domestic air pollution on current mortality patterns in England and Wales (2016) (0)
Expression of adhesion molecules in bronchial biopsies from mild asthmatic patients and normal controls and correlation with the leukocyte influx (1993) (0)
S28 Adam33 knock-out is protective against post-natal airway hyperresponsiveness caused by maternal allergy (2018) (0)
Administering and monitoring (2001) (0)
Pharmacokinetic, Cardiovascular, Respiratory and Cyclic AMP Responses to Nebulised Prostacyclin (1983) (0)
A scientific basis to the treatment of allergic diseases. (1989) (0)
Response to Responses (2020) (0)
Inhibition ofhistamine release fromdispersed humanlungand tonsillar mastcells bynicardipine andnifedipine (1985) (0)
Expression of FcεRI subunits during the in vitro differentiation of human dendritic cells (1997) (0)
Clinical evaluation of nedocromil sodium in asthma. (1987) (0)
Aortic Root to Right Heart Shunts (2009) (0)
Low levels of diesel exhaust induce airway inflammation (1999) (0)
Asthma : early predisposing factors lolo (2005) (0)
Interferon-beta for anti-virus treatment of respiratory diseases (2005) (0)
Effect oforal terfenadine onthebronchoconstrict or responsetoinhaled histamine andadenosine 5'-monophosphate innon-atopic asthma (2017) (0)
Andersen disease (2019) (0)
Proceedings of the symposium : the next step in antiallergic treatment, held during the EAACI congress, Birmingham, June 1998 (1999) (0)
[The modulator effect of bradykinin with respect to tracheobronchial clearance in healthy subjects]. (1992) (0)
Session 1. Environmental factors in allergic disorders (2004) (0)
INFβ therapy for COVID-19: the new SNG001 drug (2020) (0)
Defective Airway Epithelial Barrier and the Impact of Environmental Factors in Asthma (2018) (0)
Comprar Allergy Frontiers:Future Perspectives | Pawankar, Ruby | 9784431993643 | Springer (2010) (0)
Poster Displays ‐ Adhesion molecules June 24, 1998 (1998) (0)
The Release and Actions of Prostanoids on the Airways in Normal and Asthmatic Subjects (1985) (0)
2. The Use of Anti-allergy and Anti-asthma Drugs in the United Kingdom (1995) (0)
Characterization of a novel three‐dimensional outgrowth model of human bronchial mucosa (2011) (0)
Preface to the Eighth Edition (2013) (0)
Respiratory research in the UK: investing for the next 10 years (2022) (0)
H.H. Newball, Editor, Immunopharmacology of the Lung Volume 19, Marcel Dekker, Eastbourne (1983), p. 514. (1984) (0)
The use of competitive RT-PCR for the quantitation of cytokine mRNA in biopsies (1993) (0)
Leukotriene receptor antagonists in the management of chronic asthma (2003) (0)
Role of Mast Cells and Basophils in Asthma (Part 2 of 2) (1995) (0)
LONGITUDINAL CHANGES IN SKIN-PRICK TEST REACTIVITY - IN REPLY (1993) (0)
Beta adrenoceptors in asthma: Ed. J. Morley Florida, USA: Academic Press. 1st edition. 1984. Pp. 283. Price £14.00 (1985) (0)
H1-antihistamine efficacy: from objective assessments to symptom relief (2003) (0)
The Late Asthmatic Reaction: Its Relevance to Naturally Occuring Seasonal Allergic Asthma (1986) (0)
Asthma in Adults (2002) (0)
Pneumonia-Comorbid and Co-existing (2013) (0)
treatmentsa diagnostic test and specific syndrome/myalgic encephalomyelitis: disease Current research priorities in chronic fatigue (2007) (0)
Comprar Middleton's Allergy 2-Volume Set, 8th Edition | William W. Busse | 9780323085939 | Mosby (2013) (0)
Expression Of Interleukin 13 Receptor ± 2 In Human Bronchial Fibroblasts Requires De Novo Protein Synthesis (2012) (0)
9 a , 11 fi-Prostaglandin F 2 , a Novel Metabolite of Prostaglandin D 2 Is a Potent Contractile Agonist of Human and Guinea Pig Airways (2013) (0)
Corticosteroids and beta adrenergic agonists innormal subjects. (1977) (0)
The natural history of asthma from pre-birth to adulthood (1998) (0)
336 Production of IL-5 by Human Lung Mast Cells (1995) (0)
Repeatability and reversibility of bradykinin induced nasal symptoms and plasma protein exudation (1992) (0)
Epithelial Barrier in Allergic Diseases (2017) (0)
The Innate Anti-Viral Response Upregulates IL-13R±2 In Bronchial Fibroblasts (2012) (0)
An ex vivo model of the human airways to study the effects of long-term exposure to Space conditions (2015) (0)
human embryonic lungs. (2005) (0)
The complexity of the asthma phenotype (1998) (0)
5 Montelukast as a First Line Medication for Asthma Treatment (2002) (0)
THE IMMUNOPATHOLOGY OF FATAL ASTHMA (1998) (0)
Genetic Association Studies of IL13RA1 Polymorphisms in Asthma and Atopy (2007) (0)
Human mucosal mast cells and their mediators (1986) (0)
Comprar Middleton's Allergy 2-Volume Set, 8th Edition | William W. Busse | 9780323085939 | Mosby (2013) (0)
Anti‐IgE in Persistent Severe Allergic Asthma (2009) (0)
Poly I:C-Activated Epithelial Cells Promote The Maturation Of Dendritic Cells In A Co-Culture Model (2010) (0)
Osteocalcin, growth, andinhaled corticosteroids: aprospective study (1996) (0)
Nasal Lavage Expression of LTC4 Synthase and COX-1 Immunopositive Cells in Allergic and Idiopathic Rhinosinusitis (2001) (0)
Immunotherapy safety (2005) (0)
Should PAF inhalation challenge be used as an experimental model of bronchial hyperresponsiveness in man? (1992) (0)
Letter to the editor: Sodium cromoglycate in childhood asthma (2001) (0)
Letter to the editor: Inhaled sodium cromoglycate in children with asthma (2002) (0)
ILV7 New Concepts in Severe Asthma (2007) (0)
Even though mild asthmatic subjects have compromised antioxidant status and basal inflammation they do not exhibit heightened responsiveness to ozone (1999) (0)
Deciding when immunotherapy is appropriate (2001) (0)
Contents Vol. 149, 2009 (2009) (0)
Personalized Approaches to Severe Asthma (2017) (0)
Pharmacogenetics Working Party: introduction (2001) (0)
The Airway Mucus Regulating Transcription Factor SPDEF Is Increased In BALF In Asthma (2012) (0)
Corrigendum to “The use of omalizumab in the treatment of severe allergic asthma: A clinical experience update” [Respiratory Medicine 103 (2009) 1098–1113] (2010) (0)
Airway sensory nerve sensitivity in adolescents with eosinophilic and non-eosinophilic asthma (2020) (0)
Discussion session I: Pathophysiology in relation to treatment objectives (2001) (0)
Impaired bronchodilator responsiveness in small airways in chronic severe asthma (2003) (0)
Reply (1993) (0)
cells from patients with chronic fatigue syndrome Gene expression in peripheral blood mononuclear (2005) (0)
Intrapulmonary airways and asthma (1988) (0)
Introduction (1993) (0)
Aerosol challenge of T cell receptor transgenic mice results in down-regulation of pulmonary T cell responses (1997) (0)
Respiratory diseases are placing an increasing burden on the UK health system (2006) (0)
Endogenous IL-6 Phosphorylates STAT3 in Primary Bronchial Fibroblasts. (2009) (0)
World Allergy Forum Symposium: The Application of Monoclonal Therapies and Therapeutics to Asthma and Allergy (2008) (0)
Effects of inhaled 9 alpha, 11 beta-prostaglandin F2 on airway function in man. (1987) (0)
Anti-IgE: changing lives in clinical practice? (2007) (0)
Characterization of CBE1, a ciliated cell-associated gene induced during mucociliary differentiation (2004) (0)
The Role Of Signal Transducer And Activator Of Transcription (STAT) 3 In Interleukin-4 Signalling In Primary Fibroblasts (2011) (0)
ADAM33 protein found in bronchial brushings and biopsies is increased in bronchial carcinomas (2012) (0)
Does encasing bedding to exclude house dust mites benefit patients with rhinitis? (2004) (0)
Fluoridation: Interpreting the Newcastle fluoride bioavailability study. (2007) (0)
Antiviral Effects of Interferon beta (IFNβ) in Asthmatic Bronchial Epithelial Cell Cultures. (2009) (0)
Evaluation of successful Duration of venom immunotherapy (Table 10.5) immunotherapy (2001) (0)
Distribution anddeterminants ofpersonal exposuretonitrogen dioxide inschool children (1996) (0)
How Do Antigens Become Allergens (2014) (0)
277 Mediator release in asthma after allergen inhalation, treadmill exercise, isocapnic hyperventilation and methacholine challenge (1985) (0)
Prevalence ofatopyandrange ofbronchial response tomethacholine in7and11yearoldschoolchildren (1989) (0)
Biographical Sketch of Dr. Alec H. Sehon (1991) (0)
Adenomatous Polyposis, Familial (2009) (0)
Overview on Asthma and the Role of the Airway Epithelium (2003) (0)
Southampton . among Asian and European children in Comparison of the prevalence of asthma (0)
Physiological and Pharmacological Control of Inflammatory Mediator Release in Bronchial Asthma (1987) (0)
Enhanced sensory nerve reactivity in non-eosinophilic asthma (2021) (0)
Biographical Sketch of Dr. Alec H. Sehon (1991) (0)
The impact of tropospheric ozone on humans. (1995) (0)
LSC 2013 abstract - Mast cells support rhinovirus but not respiratory syncytial virus replication and contribute to the pro-inflammatory response to rhinovirus (2013) (0)
The distribution of adhesive mechanisms (2012) (0)
ATOPY PHENOTYPE. AUTHOR'S REPLY (1998) (0)
Therapeutic Strategies: Asthma. Modern TherapeuticTargets.RiccardoPolosaMD (2008) (0)
Interpreting the Newcastle fluoride bioavailability study (2007) (0)
Asthma (2022) (0)
ADENOSINE AND ADENOSINE ANTAGONISM IN ASTHMA. AUTHOR'S REPLY (1998) (0)
Front & Back Matter (2014) (0)
Management of asthma: Current recommendations (1994) (0)
Confidences de Salon: Stephen Holgate (2016) (0)
Pharmacogenetics Working Party (2012) (0)
Neutrophil Chemotactic Activity In The Bronchoalveolar Lavage Fluid Of Asthmatics (1993) (0)
鼻粘膜におけるケモカイン, 接着分子とアレルギー性炎症細胞の遊走・局在 (1998) (0)
1 PRO'S AND CON'S OF DIFFERENT THE RAPEUTIC APPROACHES(6 アレルギ-疾患の早期治療介入) (2000) (0)
583 ヒト肺肥満細胞におけるNF-kB活性化 (1998) (0)
216 TheophyllineのNF-κB活性化の抑制効果 (1998) (0)
ASD (2021) (0)
Risk Factors for the Development of Obstructive Airways Disease in an Elderly Population (1994) (0)
IN MEMORIAM : Lawrence M. Lichtenstein (1934-2022). (2022) (0)
WAO情報世界アレルギー機構(WAO)アレルギー白書要旨 (2011) (0)
Front & Back Matter (2016) (0)
Biochemical properties of house dust mite allergens: contributors to allergenicity? (1992) (0)
6 Role of Leukotrienes in Pathophysiology of Allergic Diseases and Their Impact on Treatment (2002) (0)
Airway Wall Remodelling in the Pathogenesis of Asthma: Cytokine Expression in the Airways (2020) (0)
THE LATE-PHASE RESPONSE AFTER CONJUNCTIVAL ALLERGEN CHALLENGE (1993) (0)
Discussuion Session 4. 'Evergreen' mediators in asthma (2004) (0)
Breathing Retraining ? : A Mechanism for * (2015) (0)
Current and future asthma therapies. (2002) (0)
Epithelial Cells Allergen on Normal and Asthmatic Bronchial Cooperative Effects of Th2 Cytokines and (2002) (0)
Subject Index Vol. 149, 2009 (2009) (0)
Clinical Development of Inhaled Interferon Beta-1a (SNG001) for the Treatment of Patients With COVID-19 in the Home and Hospital Settings (2023) (0)
Comprar Middleton's Allergy 2-Volume Set, 8th Edition | William W. Busse | 9780323085939 | Mosby (2013) (0)
Comprar Allergy Frontiers:Classification and Pathomechanisms | Pawankar, Ruby | 9784431883142 | Springer (2009) (0)
IL-13 expression by T cells in asthmatic bronchial explants and peripheral blood mononuclear cells in response to allergen (1997) (0)
The Co-Operative Effects of der P Allergen and IL-4 OR IL-13 in Cytokine Release by Bronchial Epithelial Cell Cultures of Allergic Asthmatics (2001) (0)
Comprar Middleton's Allergy: Principles and Practice, 7th Edition Expert Consult Premium Edition: Enhanced Online Features and Print, 2-Volume Set | F. Estelle R. Simons | 9780323048842 | Mosby (2009) (0)
LB1533. Impact of Treatment of Hospitalised COVID-19 Patients With Inhaled Interferon Beta-1a (SNG001) on Long COVID Symptoms: Results From the SPRINTER trial (2022) (0)
Epigenetics, allergens and risk factors (2009) (0)
Immunity Essay Does Asthma Originate in the Airway Structural Cells ? (2009) (0)
The Effect of Respirable Particles on IL-8 Release from Airway Epithelial Cells (2002) (0)
Chest physiotherapy (1989) (0)
Diagnosis and health economics (2009) (0)
Notice of duplicate publication. (1997) (0)
Comparison of 3′ and 5′ biotin labelled oligonucleotides for in situ hybridisation (1993) (0)
446 Cross-tachyphylactic studies with inhaled kinins in asthma: Evidence for partial antagonism induced by inhaled [desArg9]-Bk (1991) (0)
The place of leukotriene receptor antagonists in addressing unmet needs, including practical guidelines for prescribing physicians (1998) (0)
Comprar Allergy Frontiers:Clinical Manifestations | Pawankar, Ruby | 9784431883166 | Springer (2009) (0)
Unmet clinical needs in asthma: Childhood to old age (1998) (0)
Phenotypes and proliferative capacity of blood and BAL T cells in normaland asthmatics. (1993) (0)
treatmentsmechanisms, a diagnostic test and specific Syndrome / Myalgic Encephalomyelitis (CFS/ME): Current research priorities in Chronic Fatigue (2006) (0)
Characterisation Of Grass Pollen Derived Substances Modulating The Barrier Functions Of Bronchial Epithelial Cells (2011) (0)
19 – Concluding Remarks — Possibilities for Future Therapies (1993) (0)
6 A Susceptibility Gene in Asthma identified by positional cloning and its clinical relevance (2002) (0)
The role of T cells and their cytokines in asthma (2001) (0)
Use of Cytokine Inhibitors in Severe Asthma (2014) (0)
S27 Adam33 knockout mice have an altered metabolic transcriptional profile in response to house dust mite when compared to wild type mice (2018) (0)
Front & Back Matter (2015) (0)
Expression of Cell Adhesion Molecules in Asthma (2020) (0)
From the Authors (2004) (0)
IL13 Modelling and remodelling of the airways in asthma pathogenesis : The emergence of different phenotypes (2012) (0)
IntroductionReport of a workshop assessing the risks and benefits of inhaled anti-inflammatory treatment for asthma. (1994) (0)
289 Early T-cell changes following local allergen challenge of asthmatic bronchial mucosa (1991) (0)
Adenosine Causes Bronchoconstriction in Asthmatic but Not in Normal Subjects (1982) (0)
Interleukin -13 (IL-13) Decreases Barrier Function in Primary Bronchial Epithelial Cells. (2009) (0)
blind randomised controlled study treatment of seasonal allergic rhinitis: double Enzyme potentiated desensitisation in (2008) (0)
SS7-4 New Biologic Approaches for Treating Asthma (2008) (0)
Erratum (2012) (0)
double blind, randomised, comparative trial asthma exacerbation in adults: one year, against salmeterol and fluticasone in protecting Montelukast and fluticasone compared with (2005) (0)
Asthma and lower airway disease Identification of ATPAF 1 as a novel candidate gene for asthma in children (2011) (0)
Contents, Vol. 114, Supplment 1, 1997 (1997) (0)
[Asthma, allergy, current aspects. Report of the 4th 3A Genevan Lung and Skin: from cytopathology to clinical aspects]. (1991) (0)
Asthma Genetics (2002) (0)
[Significance of tachyphylaxis induced by repeated bradykinin inhalation in bronchial asthma]. (1989) (0)
Letter from the UK (if we still exist after recent events!) (2019) (0)
Joseph Langley Burchnall (1978) (0)
Research into lung disease: a call for urgent action (2007) (0)
Respiratory symptoms inchildren atschools near afoundry (1991) (0)
Cyclical Mechanical Stretch Enhances the Proinflammatory but not Profibrotic Responses of Asthmatic Fibroblasts (2010) (0)
Mechanisms of airways inflammation which may be amenable to prophylaxis. (1993) (0)
Effects of antioxidants on CSE-induced cell death in human asthmatic primary bronchial epithelial cells (2010) (0)
Mast cells (1991) (0)
Poster Displays ‐ lmmunomodulation June 25,1998 (1998) (0)
Prostacyclin—A Prostanoid with Differing Effects on Airway Calibre in Man (1985) (0)
Nebulised interferon-β1a (SNG001) in hospitalised COVID-19: SPRINTER phase III study (2022) (0)
Long-term effects of inhaled corticosteroids in asthmatic children (2001) (0)
Immunopathogenesis Of Asthma (1996) (0)
Mast-Cell Heterogeneity between Lung and Skin in Man (1987) (0)
Front & Back Matter (2014) (0)
Environmental interventions and interactions on wheezing (1998) (0)
Why do we not know what causes CFS and why is the field so polarized ? (2011) (0)
ES3-2 Stratified or Personalised Approaches to the Treatment of Severe Asthma (2010) (0)
Case Outcomes From Out-of-Hospital Cardiac Arrests Over a 10 Year Period in Geelong (2022) (0)
Oscillometry in the assessment of small airway function in asthma (2003) (0)
Comprar Middletons Allergy: Principles and Practice, 7th Edition Expert Consult: Online and Print, 2-Volume Set | Stephen T. Holgate | 9780323056595 | Mosby (2008) (0)
Comprar Allergy Frontiers:Therapy and Prevention | Pawankar, Ruby | 9784431993612 | Springer (2009) (0)
A retrospective review of Listeria monocytogenes infection at Tygerberg Children's Hospital, Cape Town, South Africa, from 2006 to 2016: Is empirical ampicillin still indicated after the first month of life? (2018) (0)
The temporal expression of ciliated bronchial epithelium (CBE) 1 in embryonic lungs. (2006) (0)
The use of pharmacogenetics in the treatment of asthma. (2005) (0)
Interleukin-4 levels in peripheral blood CD8+ T cells in mild atopic asthmatics (1997) (0)
THE CELLULAR-RESPONSE TO CONJUNCTIVAL ALLERGEN CHALLENGE (1993) (0)
Editorial. (2020) (0)
children . exposure to nitrogen dioxide in school Distribution and determinants of personal (2005) (0)
Low baseline nasal respiratory tract lining fluid urate concentrations in mild asthmatic subjects restricts their capacity to scrub ozone. (1999) (0)
Leukotrienes in Aspirin‐Intolerant Asthma (2004) (0)
SL3 Rethinking the origins and pathogenesis of asthma (2009) (0)
Purchasing Research from or for the NHS? (1994) (0)
Atopy phenotype. (1998) (0)
Wnt Signal Transduction in Adult Human Bronchial Epithelial Cells (2003) (0)
A Conduit for Infiltrating Cells (2001) (0)
Disruption of Airway Epithelium in Asthma Pathogenesis: Are Protozoa Responsible? (2012) (0)
Interferon Beta (IFN²) Is Equally Effective At Inhibiting Rhinovirus Infection In Primary Bronchial Epithelial Cells Of Long Term Smokers (with And Without COPD) And Younger Non-smoking Subjects (2010) (0)
Candidate locus approach for studying the genetics of asthma and atopy. (1997) (0)
IL4 ADAM33 and the Epithelial Mesenchymal Trophic Unit (2008) (0)
S29 The effect of soluble ADAM33 on allergic airway inflammation in early life is age dependent (2018) (0)
bronchial epithelial wound repair isoform release and activation during in vitro (2013) (0)
Preface (1999) (0)
Andrew Szczeklik: a clinical scientist of the highest calibre (2012) (0)
S130 Maternal allergic airway inflammation during pregnancy alters offspring’s airway hyperresponsiveness dependent on muscarinic receptor and adam33 mediated mechanisms (2019) (0)
Discussion session II: Inflammation (2001) (0)
Comparison of restriction digest and amplification refractory mutation system for determining the genotype of patients with undetectable TPMT activity (2006) (0)
Differentiated Bronchial Epithelial Cells Suppress Antigen-Mediated Mast Cell Activation Following Co-Culture (2012) (0)
Chairman’s summary (2001) (0)
Comprar Inflammation And Allergy Drug Design | Kenji Izuhara | 9781444330144 | Wiley (2011) (0)
Report oof aa w workshop aassessing tthe rrisks aand bbenefits oof iinhaled (1994) (0)
Update on the SNG001 drug, an INFβ therapy for COVID-19 (2020) (0)
Reply (1985) (0)
Chronological expression of ciliated bronchial epithelim 1 in mouse and human pulmonary differentiation (2006) (0)
Letter: Intravenous prednisolone in asthma. (1976) (0)
AUTHORS' REPLY (1993) (0)
Poster Presentation (2022) (0)
Leukotriene C4 Synthase Gene Polymorphism in Severe Asthma (2001) (0)
Soluble Adam33 Is Increased And Enzymatically Active In BALF And Is Associated With Bronchial Hyperresponsiveness In Il-13 Overexpressing Mice (2012) (0)
Front & Back Matter (2014) (0)
Expression of FcεRI by dendritic cells from normals and asthmatics (1997) (0)
ADAM33 is involved in post-natal airway hyperresponsiveness caused by maternal allergic airway inflammation (2018) (0)
The history of drug development and asthma management (1998) (0)
An overview of the safety of inhaled corticosteroids. (1994) (0)

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