Steven Block

Q: What Schools Are Affiliated With Steven Block

Steven Block is affiliated with the following schools: University of Oxford, University of Alberta, Princeton University, Stanford University, University of Colorado, West Virginia University, Harvard University

Steven Block's AcademicInfluence.com Rankings

Steven Block

Physics

#1669

World Rank

#2545

Historical Rank

#690

USA Rank

Biophysics

#50

World Rank

#54

Historical Rank

#18

USA Rank

physics Degrees

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Physics

Why Is Steven Block Influential?

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According to Wikipedia, Steven M. Block is an American biophysicist and Professor at Stanford University with a joint appointment in the departments of Biology and Applied Physics. In addition, he is a member of the scientific advisory group JASON, a senior fellow of Stanford's Freeman Spogli Institute for International Studies, and an amateur bluegrass musician. Block received his B.A. and M.A. from Oxford University. He has been elected to the U.S. National Academy of Sciences and the American Academy of Arts and Sciences , and is a winner of the Max Delbruck Prize of the American Physical Society , as well as the Single Molecule Biophysics Prize of the Biophysical Society . He served as President of the Biophysical Society during 2005-6. His graduate work was completed in the laboratory of Howard Berg at the University of Colorado and Caltech. He received his Ph.D. in 1983 and went on to do postdoctoral research at Stanford. Since that time, Block has held positions at the Rowland Institute for Science, Harvard University, and Princeton University before returning to Stanford in 1999.

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Steven Block's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Direct observation of kinesin stepping by optical trapping interferometry (1993) (1750)
Biological applications of optical forces. (1994) (1721)
Stretching DNA with optical tweezers. (1997) (1307)
Optical trapping. (2004) (1305)
Bead movement by single kinesin molecules studied with optical tweezers (1990) (1010)
Single kinesin molecules studied with a molecular force clamp (1999) (943)
Force and velocity measured for single kinesin molecules (1994) (860)
Force and velocity measured for single molecules of RNA polymerase. (1998) (845)
Direct observation of base-pair stepping by RNA polymerase (2005) (819)
Kinesin hydrolyses one ATP per 8-nm step (1997) (712)
Characterization of photodamage to Escherichia coli in optical traps. (1999) (702)
Optical trapping of metallic Rayleigh particles. (1994) (663)
Estimating the persistence length of a worm-like chain molecule from force-extension measurements. (1999) (611)
Transcription Against an Applied Force (1995) (546)
Force production by single kinesin motors (2000) (535)
Kinesin Moves by an Asymmetric Hand-Over-Hand Mechanism (2003) (524)
Temporal comparisons in bacterial chemotaxis. (1986) (492)
High-resolution, single-molecule measurements of biomolecular motion. (2007) (446)
Construction of multiple-beam optical traps with nanometer-resolution position sensing (1996) (441)
Compliance of bacterial flagella measured with optical tweezers (1989) (430)
Developmental Regulation of Vesicle Transport in Drosophila Embryos: Forces and Kinetics (1998) (383)
Direct Observation of Hierarchical Folding in Single Riboswitch Aptamers (2008) (377)
Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins. (2006) (361)
Backtracking by single RNA polymerase molecules observed at near-base-pair resolution (2003) (349)
Direct Measurement of the Full, Sequence-Dependent Folding Landscape of a Nucleic Acid (2006) (338)
Optical tweezers study life under tension. (2011) (328)
Ubiquitous Transcriptional Pausing Is Independent of RNA Polymerase Backtracking (2003) (326)
Kinesin motor mechanics: binding, stepping, tracking, gating, and limping. (2007) (307)
Adaptation kinetics in bacterial chemotaxis (1983) (299)
Probing the kinesin reaction cycle with a 2D optical force clamp (2003) (290)
Sequence-Resolved Detection of Pausing by Single RNA Polymerase Molecules (2006) (287)
Coordination of opposite-polarity microtubule motors (2002) (286)
An automated two-dimensional optical force clamp for single molecule studies. (2002) (285)
Impulse responses in bacterial chemotaxis (1982) (285)
Fluctuation analysis of motor protein movement and single enzyme kinetics. (1994) (278)
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro (2006) (269)
A pause sequence enriched at translation start sites drives transcription dynamics in vivo (2014) (245)
Stretching of single collapsed DNA molecules. (2000) (239)
Dynein-mediated cargo transport in vivo. A switch controls travel distance. (2000) (225)
Simultaneous, coincident optical trapping and single-molecule fluorescence (2004) (223)
Resource Letter: LBOT-1: Laser-based optical tweezers. (2003) (214)
Successive incorporation of force-generating units in the bacterial rotary motor (1984) (214)
Passive all-optical force clamp for high-resolution laser trapping. (2005) (212)
Single-molecule studies of RNA polymerase: motoring along. (2008) (191)
Reconstructing folding energy landscapes by single-molecule force spectroscopy. (2014) (186)
A universal pathway for kinesin stepping (2011) (176)
Making light work with optical tweezers (1992) (171)
Applied Force Reveals Mechanistic and Energetic Details of Transcription Termination (2008) (170)
Conformation and elasticity of the isolated red blood cell membrane skeleton. (1992) (169)
Direct Observation of Cotranscriptional Folding in an Adenine Riboswitch (2012) (166)
A miniature flow cell designed for rapid exchange of media under high-power microscope objectives. (1984) (165)
Versatile optical traps with feedback control. (1998) (158)
A DNA-based molecular probe for optically reporting cellular traction forces (2014) (153)
Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain. (2006) (142)
Examining kinesin processivity within a general gating framework (2015) (136)
Sequence-Dependent Pausing of Single Lambda Exonuclease Molecules (2003) (133)
Forward and reverse motion of single RecBCD molecules on DNA. (2004) (133)
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II (2012) (120)
Stepping and Stretching (2003) (120)
Statistical kinetics of processive enzymes. (1995) (119)
E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. (2010) (113)
Direct observation of the binding state of the kinesin head to the microtubule (2009) (111)
Single-Molecule, Motion-Based DNA Sequencing Using RNA Polymerase (2006) (111)
Kinesin processivity is gated by phosphate release (2014) (109)
Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes. (2011) (103)
Combined optical trapping and single-molecule fluorescence (2003) (100)
Folding and unfolding single RNA molecules under tension. (2008) (97)
Coordination of flagella on filamentous cells of Escherichia coli (1983) (95)
Kinesin: What Gives? (1998) (95)
Fifty Ways to Love Your Lever: Myosin Motors (1996) (94)
Optical tweezers : a new tool for biophysics (1990) (92)
Movement of myosin fragments in vitro: Domains involved in force production (1987) (81)
Measurement of the effective focal shift in an optical trap. (2005) (78)
The importance of lattice defects in katanin-mediated microtubule severing in vitro. (2002) (77)
Precision steering of an optical trap by electro-optic deflection. (2008) (74)
Compliance of bacterial polyhooks measured with optical tweezers. (1991) (73)
Folding energy landscape of the thiamine pyrophosphate riboswitch aptamer (2012) (72)
The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load (2015) (72)
Real-Time Observation of the Initiation of RNA Polymerase II Transcription (2015) (72)
Statistical kinetics of macromolecular dynamics. (2005) (70)
Factor-dependent processivity in human eIF4A DEAD-box helicase (2015) (70)
Motor proteins. (1991) (68)
Morphology and dynamics of protruding spirochete periplasmic flagella (1992) (67)
Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. (2006) (65)
Eg5 steps it up! (2006) (63)
Picocalorimetry of transcription by RNA polymerase. (2005) (61)
Myosin movement in vitro: a quantitative assay using oriented actin cables from Nitella. (1986) (61)
Nanometres and piconewtons: the macromolecular mechanics of kinesin. (1995) (60)
Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms (2014) (60)
The Growing Threat of Biological Weapons (2001) (55)
Binding and translocation of termination factor rho studied at the single-molecule level. (2012) (55)
An optical apparatus for rotation and trapping. (2010) (51)
Single-molecule studies of riboswitch folding. (2014) (50)
Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA. (2011) (47)
Real engines of creation (1997) (47)
Actin cores of hair-cell stereocilia support myosin motility. (1990) (46)
Visualization of bacterial flagella by video-enhanced light microscopy (1991) (44)
Direct measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping (2009) (44)
Analysis of high resolution recordings of motor movement. (1995) (44)
Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load (2017) (40)
Leading the Procession: New Insights into Kinesin Motors (1998) (39)
A mutant hook-associated protein (HAP3) facilitates torsionally induced transformations of the flagellar filament of Escherichia coli. (1994) (39)
Do's and don't's of poster presentation. (1996) (38)
Electrostatics of nucleic acid folding under conformational constraint. (2012) (33)
Force and premature binding of ADP can regulate the processivity of individual Eg5 dimers. (2009) (31)
On the origin of kinesin limping. (2009) (30)
Light and dark adaptation in Phycomyces light-growth response (1983) (30)
KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics (2018) (30)
Single-molecule studies of RNAPII elongation. (2013) (29)
Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer (2015) (28)
Kinesin steps do not alternate in size. (2008) (26)
Direct observation of processive exoribonuclease motion using optical tweezers (2015) (23)
Dynein-Mediated Cargo Transport in Vivo (2000) (22)
Visualizing individual microtubules by bright field microscopy (2009) (18)
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II (2012) (18)
Computerized video analysis of tethered bacteria (1987) (16)
One small step for myosin... (1995) (15)
Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme (2020) (15)
A Not-So-Cheap Stunt (2002) (15)
Self-cleavage of the glmS ribozyme core is controlled by a fragile folding element (2018) (12)
Real-time observation of polymerase-promoter contact remodeling during transcription initiation (2017) (9)
Molecule by molecule, the physics and chemistry of life: SMB 2007. (2007) (6)
Observing Single RNA Polymerase Molecules Down to Base-Pair Resolution. (2017) (5)
Characterization of photodamage induced by optical tweezers (1998) (5)
Fluctuation analysis of kinesin movement. (1995) (5)
Not so lame after all: kinesin still walks with a hobbled head. (2007) (4)
High-resolution single-molecule optical trapping measurements of transcription with basepair accuracy: instrumentation and methods (2007) (2)
Direct Observation of Individual Kinesin Head Motions (2009) (2)
Getting high on Single Molecule Biophysics. (2009) (2)
TFIIF and TFIIS Enhance the Mechanical Persistence of Transcript Elongation by RNA Polymerase II (2014) (2)
Fifty Ways to Love Your Lever: Review Myosin Motors (1996) (2)
Real-time observation of polymerase-promoter contact remodeling during transcription initiation (2017) (2)
, PROCESSIVELY USES INTERNAL STRAIN TO WALK Stepping and Stretching : HOW KINESIN REGULATION : ENZYME CATALYSIS (2003) (2)
The Growing Threat of Biological Weapons The terrorist threat is very real, and it's about to get worse. Scientists should concern themselves before it's too late (2006) (2)
Not So Lame After All: Kinesin Still Walks with a Hobbled Head (2007) (2)
Book Review:Methods in Cell Biology. Volume 39: Motility Assays for Motor Proteins. Jonathan M. Scholey (1995) (1)
Comprehensive Sequence-to-Function Mapping of Ligand-Dependent RNA Catalysis (2021) (1)
DNA Barcodes and Watermarks (2004) (1)
The molecular physics of biological movement: General discussion (2000) (1)
RNA Polymerase II Translocation and Fidelity are Governed by Trigger Loop Dynamics: A Single-Molecule Study (2012) (1)
The Isolated Human Red Blood Cell Skeleton: An Example of a Flexible Tethered Membrane (1992) (1)
Mechanochemical Properties of the Kinesin-2 Motor, KIF3A/B, Studied by Optical Trapping (2011) (1)
An Optical Torque Wrench For Studying Kinesin Dynamics (2009) (1)
Folding and Catalysis of the glmS Ribozyme Riboswitch Studied at the Single-Molecule Level (2016) (1)
Faculty Opinions recommendation of Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes. (2007) (0)
4.18 Kinesin Single-Molecule Mechanics (2012) (0)
ANALYSIS OF HIGH RESOLUTION RECORDINGS OF MOTOR MOVEMENT. DISCUSSION (1995) (0)
The Biophysics of Gene Regulation, Studied One Molecule at a Time (2008) (0)
Macromolecular physiology. One small step for myosin... (1995) (0)
Single Molecule Studies Reveal the Mechanism and Energetics of Transcriptional Termination (2008) (0)
Scattering Studies of the Isolated Red Blood Cell Skeleton, a Biological Two-Dimensional Polymer (1991) (0)
Chemotactic Responses of Tethered Bacteria (1983) (0)
Using laser tweezers to measure forces generated by biological molecular motors (2003) (0)
Single-Molecule Nanomechanics of Kinesin and Kinesin-Family Proteins (2018) (0)
THE MECHANICS OF FORCE GENERATION BY KINESIN. DISCUSSION (1995) (0)
Biophysics: Breaking the Nanometer Barrier (2006) (0)
PATHWAY OF THE MICROTUBULE-KINESIN ATPASE. DISCUSSION (1995) (0)
Author response: Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer (2015) (0)
Motor proteins (J. Cell Sci. Suppl. 14): edited by R. A. Cross and J. Kendrick-Jones, Portland Press, 1991. $60.00 (vii + 168 pages) ISBN 0 948601 29 9 (1992) (0)
Riboswitch Folding Kinetics can Affect Gene Expression by a Translationally Acting Riboswitch (2012) (0)
Single kinesinmolecules studiedwithamolecular forceclamp (0)
Using optical tweezers to study biological motors and cellular structures (1993) (0)
Advances in Single Molecule Biophysics: Breaking the Nanometer Barrier with Optical Tweezers (2007) (0)
Massa An Optical Apparatus for Rotation and Trapping (2010) (0)
Supplementary Online Material for : Binding and Translocation of Termination Factor Rho Studied at the Single-Molecule Level (2016) (0)
Mechanism Kinesin Moves by an Asymmetric Hand-OverHand (2008) (0)
Shedding Light on Single Molecules (2012) (0)
Folding of the Thiamine Pyrophosphate (TPP) Riboswitch (2010) (0)
UK defence group's structure could limit its usefulness (2009) (0)
Modulation Of Sequence-dependent Pausing Of RNA Polymerase By The Accessory Factor Nusa: A Single-molecule Study (2009) (0)
Author response: Examining kinesin processivity within a general gating framework (2015) (0)
Faculty Opinions recommendation of Stabilization of an optical microscope to 0.1 nm in three dimensions. (2007) (0)
High-Resolution, Single-Molecule (2007) (0)
Effects of Neck Linker Length on Kinesin-1 Force Generation and Motility (2013) (0)
Relationship between Folding and Catalysis in the GLMS Ribozyme Riboswitch (2018) (0)
Role of ponticulin in pseudopod dynamics, cell-cell adhesion, and mechanical stability of an amoeboid membrane skeleton. (1998) (0)

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