Steven E. Kahn

Q: What Schools Are Affiliated With Steven E. Kahn

Steven E. Kahn is affiliated with the following schools: University of Arkansas for Medical Sciences, George Washington University, University of California, Berkeley, University of Cape Town, University of Arizona, Stanford University, University of Washington

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Steven E. Kahn

Engineering

#2213

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#3086

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Electrical Engineering

#366

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#411

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engineering Degrees

Steven E. Kahn

Computer Science

#3140

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#3291

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Computational Linguistics

#117

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#120

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Machine Learning

#304

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#308

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Artificial Intelligence

#480

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#489

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computer-science Degrees

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Engineering
Computer Science

Steven E. Kahn's Degrees

PhD Computer Science Stanford University
Masters Electrical Engineering University of California, Berkeley
Bachelors Computer Engineering University of California, Berkeley

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Steven E. Kahn's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mechanisms linking obesity to insulin resistance and type 2 diabetes (2006) (4515)
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. (2006) (2910)
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes (2003) (2054)
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. (2013) (1520)
Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes (2007) (1502)
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex (2003) (1449)
Quantification of the Relationship Between Insulin Sensitivity and β-Cell Function in Human Subjects: Evidence for a Hyperbolic Function (1993) (1434)
Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future (2014) (1260)
Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity* (2004) (1178)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes (2010) (1141)
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. (2004) (985)
Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial (2019) (749)
Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions. (2008) (730)
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. (2003) (683)
Review: The role of insulin resistance in nonalcoholic fatty liver disease. (2006) (683)
Effect of valsartan on the incidence of diabetes and cardiovascular events. (2010) (626)
The Importance of β-Cell Failure in the Development and Progression of Type 2 Diabetes (2001) (624)
Glucose levels and risk of dementia. (2013) (588)
Inhibition of hypothalamic neuropeptide Y gene expression by insulin. (1992) (573)
Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes. (2004) (530)
Rosiglitazone-Associated Fractures in Type 2 Diabetes (2008) (509)
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. (1993) (502)
Differences in A1C by Race and Ethnicity Among Patients With Impaired Glucose Tolerance in the Diabetes Prevention Program (2007) (497)
Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized? (2011) (482)
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes. (1999) (467)
Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. (2005) (453)
The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations : distinct metabolic effects of two fat compartments. (2002) (447)
Effect of nateglinide on the incidence of diabetes and cardiovascular events. (2010) (440)
Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. (2005) (439)
Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. (2005) (425)
Evidence of Cosecretion of Islet Amyloid Polypeptide and Insulin by β-Cells (1990) (411)
Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial. (2019) (359)
Clinical review 135: The importance of beta-cell failure in the development and progression of type 2 diabetes. (2001) (327)
Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels (2009) (314)
beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms. (2001) (314)
Obesity and type 2 diabetes: what can be unified and what needs to be individualized? (2011) (312)
Effect of a 12-Month Intensive Lifestyle Intervention on Hepatic Steatosis in Adults With Type 2 Diabetes (2010) (312)
Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans (2010) (311)
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. (2000) (310)
Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal. (1994) (297)
Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S. (2002) (296)
The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-abdominal fat. (2003) (290)
Role of Glucose Effectiveness in the Determination of Glucose Tolerance (1996) (285)
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. (1996) (280)
Visceral Adiposity Is an Independent Predictor of Incident Hypertension in Japanese Americans (2004) (279)
The effect of intensive endurance exercise training on body fat distribution in young and older men. (1991) (278)
Effects of Physical Conditioning on Fibrinolytic Variables and Fibrinogen in Young and Old Healthy Adults (1991) (261)
Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats. (1991) (260)
β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition. (2011) (259)
The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality (2009) (256)
Obesity, body fat distribution, insulin sensitivity and Islet beta-cell function as explanations for metabolic diversity. (2001) (254)
A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes. (2002) (249)
Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. (1998) (231)
Visceral adiposity and the risk of impaired glucose tolerance: a prospective study among Japanese Americans. (2003) (229)
Reduced Sample Number for Calculation of Insulin Sensitivity and Glucose Effectiveness From the Minimal Model: Suitability for Use in Population Studies (1993) (229)
The evolution of β‐cell dysfunction and insulin resistance in type 2 diabetes (2002) (228)
Release of Incompletely Processed Proinsulin Is the Cause of the Disproportionate Proinsulinemia of NIDDM (1997) (227)
Design and baseline characteristics of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA®) (2015) (215)
Effect of exercise on insulin action, glucose tolerance, and insulin secretion in aging. (1990) (214)
Rationale and Design of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) (2013) (212)
Hyperproinsulinemia and Amyloid in NIDDM: Clues to Etiology of Islet β-Cell Dysfunction? (1989) (212)
Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. (2014) (211)
Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus. (1990) (210)
Effects of Rosiglitazone, Glyburide, and Metformin on β-Cell Function and Insulin Sensitivity in ADOPT (2011) (202)
The Contribution of Insulin-Dependent and Insulin-Independent Glucose Uptake to Intravenous Glucose Tolerance in Healthy Human Subjects (1994) (196)
Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone: A Preliminary Study (2005) (195)
Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis (2009) (195)
Visceral Adiposity, Not Abdominal Subcutaneous Fat Area, Is Associated With an Increase in Future Insulin Resistance in Japanese Americans (2008) (193)
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. (1990) (189)
Obesity Is a Major Determinant of the Association of C-Reactive Protein Levels and the Metabolic Syndrome in Type 2 Diabetes (2006) (187)
Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes (2015) (183)
Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans (2005) (179)
Phenotypic characteristics of GAD antibody-positive recently diagnosed patients with type 2 diabetes in North America and Europe. (2004) (177)
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence? (2010) (176)
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials (2010) (173)
Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program (2011) (173)
Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes. (2010) (172)
Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials (2012) (170)
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. (1991) (167)
Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. (1990) (165)
Impact of Intensive Lifestyle Intervention on Depression and Health-Related Quality of Life in Type 2 Diabetes: The Look AHEAD Trial (2014) (163)
Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men. (2000) (163)
Regression From Pre-Diabetes to Normal Glucose Regulation in the Diabetes Prevention Program (2009) (157)
Adiponectin, Change in Adiponectin, and Progression to Diabetes in the Diabetes Prevention Program (2008) (155)
Heritability of pancreatic beta-cell function among nondiabetic members of Caucasian familial type 2 diabetic kindreds. (1999) (155)
The prevention of type 2 diabetes (2008) (155)
Adiponectin and beta cell dysfunction in gestational diabetes: pathophysiological implications (2005) (152)
Impact of an Intensive Lifestyle Intervention on Use and Cost of Medical Services Among Overweight and Obese Adults With Type 2 Diabetes: The Action for Health in Diabetes (2014) (149)
Reduced insulin secretion: an independent predictor of body weight gain. (1995) (145)
Increased β-Cell Secretory Capacity as Mechanism for Islet Adaptation to Nicotinic Acid-Induced Insulin Resistance (1989) (143)
Differences in Cardiovascular Responses to Isoproterenol in Relation to Age and Exercise Training in Healthy Men (1992) (141)
Towards a Consensus-Based Classification of Childhood Arterial Ischemic Stroke (2012) (138)
Proinsulin as a Marker for the Development of NIDDM in Japanese-American Men (1995) (136)
Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation (2005) (136)
Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment. (2011) (133)
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. (2007) (133)
Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet. (2005) (132)
The importance of the β-cell in the pathogenesis of type 2 diabetes mellitus (2000) (129)
- Cell Function Is a Major Contributor to Oral Glucose Tolerance in High-Risk Relatives of Four Ethnic Groups in the U . (2002) (128)
Visceral Adiposity and the Prevalence of Hypertension in Japanese Americans (2003) (126)
Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study (2017) (124)
Correlations of In Vivo β-Cell Function Tests With β-Cell Mass and Pancreatic Insulin Content in Streptozocin-Administered Baboons (1991) (120)
Type 2 Diabetes–Associated Missense Polymorphisms KCNJ11 E23K and ABCC8 A1369S Influence Progression to Diabetes and Response to Interventions in the Diabetes Prevention Program (2007) (120)
Optimum BMI Cut Points to Screen Asian Americans for Type 2 Diabetes (2015) (119)
The effect of insulin dose on the measurement of insulin sensitivity by the minimal model technique. Evidence for saturable insulin transport in humans. (1996) (119)
The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus. (2000) (119)
Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial (2021) (119)
Evidence That Plasma Leptin and Insulin Levels are Associated With Body Adiposity Via Different Mechanisms (1997) (117)
Body fat distribution in healthy young and older men. (1990) (115)
Reduced beta-cell compensation to the insulin resistance associated with obesity in members of caucasian familial type 2 diabetic kindreds. (2000) (112)
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid. (2003) (112)
Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats (1990) (112)
Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum (2016) (109)
Adherence to Preventive Medications (2006) (109)
Differential Effects of Abdominal Adipose Tissue Distribution on Insulin Sensitivity in Black and White South African Women (2009) (109)
Insulin Transport From Plasma Into the Central Nervous System Is Inhibited by Dexamethasone in Dogs (1996) (108)
The visceral adiposity syndrome in Japanese-American men. (1994) (106)
Enhanced cortisol production rates, free cortisol, and 11beta-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss. (2009) (105)
Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program (2012) (105)
Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? (2001) (104)
Importance of early phase insulin secretion to intravenous glucose tolerance in subjects with type 2 diabetes mellitus. (2001) (104)
Cholesterol Feeding Increases C-Reactive Protein and Serum Amyloid A Levels in Lean Insulin-Sensitive Subjects (2005) (103)
Comparison of a clinical model, the oral glucose tolerance test, and fasting glucose for prediction of type 2 diabetes risk in Japanese Americans. (2003) (102)
Current status of islet cell replacement and regeneration therapy. (2010) (101)
Effects of Insulin Resistance and Obesity on Lipoproteins and Sensitivity to Egg Feeding (2003) (101)
Impact of Intra-Abdominal Fat and Age on Insulin Sensitivity and β-Cell Function (2004) (99)
Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studies (2007) (98)
Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. (1990) (98)
Nonprogression of Subclinical β-Cell Dysfunction Among First-Degree Relatives of IDDM Patients: 5-Yr Follow-Up of the Seattle Family Study (1990) (96)
Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responses. (2006) (96)
Continuous measurement of oxygen consumption by pancreatic islets. (2002) (95)
Change in Visceral Adiposity Independently Predicts a Greater Risk of Developing Type 2 Diabetes Over 10 Years in Japanese Americans (2013) (93)
Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: a study with the euglycemic-hyperinsulinemic clamp. (2010) (93)
Pancreatic Expression and Secretion of Human Islet Amyloid Polypeptide in a Transgenic Mouse (1994) (92)
Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes. (2007) (92)
Impact of Insulin and Metformin Versus Metformin Alone on β-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes (2018) (91)
Effects of Weight Loss, Weight Cycling, and Weight Loss Maintenance on Diabetes Incidence and Change in Cardiometabolic Traits in the Diabetes Prevention Program (2014) (91)
Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT) rationale and design. (2020) (90)
COVID-19, Hyperglycemia, and New-Onset Diabetes (2021) (89)
Direct Autocrine Action of Insulin on β-Cells: Does It Make Physiological Sense? (2013) (88)
Factors Associated With Diabetes Onset During Metformin Versus Placebo Therapy in the Diabetes Prevention Program (2007) (87)
Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide. (2005) (87)
SE. Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels. Diabetes Care 2009;32:335―341 (2009) (87)
Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: follow-up of the Seattle Family Study. (1999) (86)
Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans. (1996) (84)
We Can Change the Natural History of Type 2 Diabetes (2014) (84)
Improvement of BMI, body composition, and body fat distribution with lifestyle modification in Japanese Americans with impaired glucose tolerance. (2002) (84)
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database (2006) (83)
Patterns of Insulin Concentration During the OGTT Predict the Risk of Type 2 Diabetes in Japanese Americans (2013) (83)
Insulin Response in Relation to Insulin Sensitivity (2009) (81)
COVID-19 in People With Diabetes: Urgently Needed Lessons From Early Reports (2020) (80)
Ethnic differences in serum lipoproteins and their determinants in South African women. (2010) (80)
The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose. (2008) (79)
Type 2 diabetes and the metabolic syndrome in Japanese Americans. (2000) (78)
Low Clusterin Levels in High-Density Lipoprotein Associate With Insulin Resistance, Obesity, and Dyslipoproteinemia (2010) (78)
Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells. (2001) (78)
A reduced-fat diet and aerobic exercise in Japanese Americans with impaired glucose tolerance decreases intra-abdominal fat and improves insulin sensitivity but not beta-cell function. (2005) (77)
HbA1c as a Predictor of Diabetes and as an Outcome in the Diabetes Prevention Program: A Randomized Clinical Trial (2014) (77)
Diet-induced weight loss is associated with an improvement in beta-cell function in older men. (2004) (77)
Effect of troglitazone on B cell function, insulin sensitivity, and glycemic control in subjects with type 2 diabetes mellitus. (1998) (76)
Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans. (1998) (76)
Relationship of proinsulin and insulin with noninsulin-dependent diabetes mellitus and coronary heart disease in Japanese-American men: impact of obesity--clinical research center study. (1995) (75)
Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program (2009) (73)
Restoring Insulin Secretion (RISE): Design of Studies of β-Cell Preservation in Prediabetes and Early Type 2 Diabetes Across the Life Span (2013) (73)
Contribution of metabolic factors to alanine aminotransferase activity in persons with other causes of liver disease. (2005) (72)
The Pro12Ala variant at the peroxisome proliferator-activated receptor γ gene and change in obesity-related traits in the Diabetes Prevention Program (2007) (72)
Greater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans. (2011) (71)
Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD. (2016) (71)
Fibrinolytic response during exercise and epinephrine infusion in the same subjects. (1992) (70)
Reduced β-cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding. (1999) (70)
Body mass index is associated with increased creatinine clearance by a mechanism independent of body fat distribution. (2009) (69)
A Diabetes Outcome Progression Trial (ADOPT): baseline characteristics of Type 2 diabetic patients in North America and Europe (2006) (69)
Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress (2009) (69)
cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets (2011) (69)
The GENNID Study: A resource for mapping the genes that cause NIDDM (1996) (68)
Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA. (2019) (68)
Renal function in type 2 diabetes with rosiglitazone, metformin, and glyburide monotherapy. (2011) (67)
Is central obesity associated with cirrhosis-related death or hospitalization? A population-based, cohort study. (2005) (67)
Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets (2008) (66)
Exercise training delineates the importance of B-cell dysfunction to the glucose intolerance of human aging. (1992) (65)
Incretin Therapy and Islet Pathology: A Time for Caution (2013) (65)
Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia (2020) (65)
Altered body composition in type 2 diabetes mellitus (2008) (64)
Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice (2014) (64)
Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials (2015) (64)
Nicotinamide's Effects on Glucose Metabolism in Subjects at Risk For IDDM (1996) (64)
Intra-abdominal fat accumulation predicts the development of the metabolic syndrome in non-diabetic Japanese-Americans (2007) (64)
Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: Results from the look AHEAD randomized trial (2012) (63)
Relationship of Insulin Sensitivity and ApoB Levels to Intra-abdominal Fat in Subjects With Familial Combined Hyperlipidemia (2001) (63)
Physical activity, sedentary behaviors, and estimated insulin sensitivity and secretion in pregnant and non-pregnant women (2011) (63)
A Variation at Position −30 of the β-Cell Glucokinase Gene Promoter Is Associated With Reduced β-Cell Function in Middle-Aged Japanese-American Men (1996) (62)
Visceral fat resection in humans: Effect on insulin sensitivity, beta‐cell function, adipokines, and inflammatory markers (2013) (62)
Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program (2008) (61)
Correlations of in vivo beta-cell function tests with beta-cell mass and pancreatic insulin content in streptozocin-administered baboons. (1991) (61)
Reduced pancreatic B cell compensation to the insulin resistance of aging: impact on proinsulin and insulin levels. (2000) (59)
Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. (1989) (59)
An examination of β‐cell function measures and their potential use for estimating β‐cell mass (2008) (58)
Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes. (2002) (57)
Abnormal glucose tolerance and increased risk for cardiovascular disease in Japanese-Americans with normal fasting glucose. (2001) (56)
Effects of Sex and Hormone Replacement Therapy Use on the Prevalence of Isolated Impaired Fasting Glucose and Isolated Impaired Glucose Tolerance in Subjects With a Family History of Type 2 Diabetes (2006) (55)
The key role of islet dysfunction in type II diabetes mellitus. (1995) (54)
Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment (2017) (54)
Postmenopausal Hormone Therapy Is Associated With Atherosclerosis Progression in Women With Abnormal Glucose Tolerance (2004) (54)
Effect of intensive endurance training on lipoprotein profiles in young and older men. (1992) (53)
Risk factors for type 2 diabetes: Lessons learned from Japanese Americans in Seattle (2012) (53)
Steroid Sex Hormones, Sex Hormone-Binding Globulin, and Diabetes Incidence in the Diabetes Prevention Program. (2015) (52)
Increased Visceral Adipose Tissue Is an Independent Predictor for Future Development of Atherogenic Dyslipidemia. (2016) (52)
The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program. (2009) (52)
The effect of vitamin therapy on the progression of coronary artery atherosclerosis varies by haptoglobin type in postmenopausal women. (2004) (52)
Insulin Response in Relation to Insulin Sensitivity: An Appropriate β-Cell Response in Black South African Women (2009) (51)
Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets (2011) (50)
Preeclampsia and Risk of Developing Subsequent Diabetes (2009) (50)
Colesevelam Improves Oral but Not Intravenous Glucose Tolerance by a Mechanism Independent of Insulin Sensitivity and β-Cell Function (2012) (50)
Paricalcitol does not improve glucose metabolism in patients with stage 3-4 chronic kidney disease (2012) (50)
Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. (1992) (49)
Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study (2017) (49)
Islet dysfunction in non-insulin-dependent diabetes mellitus. (1988) (48)
Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke. (2010) (48)
Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-h Glucose Levels (2009) (48)
Insulin, C-peptide, and leptin concentrations predict increased visceral adiposity at 5- and 10-year follow-ups in nondiabetic Japanese Americans. (2005) (47)
Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program (2012) (47)
Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro. (2007) (47)
Depressive Symptoms in Pulmonary Arterial Hypertension: Prevalence and Association With Functional Status (2010) (46)
Metabolic syndrome and coronary angiographic disease progression: the Women's Angiographic Vitamin & Estrogen trial. (2003) (46)
Review of methods for measuring β‐cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium (2018) (46)
The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial (2017) (46)
Effect of insulin resistance and hyperglycemia on proinsulin release in a primate model of diabetes mellitus. (1992) (46)
Effect of heparin on insulin-glucose interactions measured by the minimal model technique: implications for reproducibility using this method. (1993) (46)
Depressive symptoms in pulmonary arterial hypertension: prevalence and association with functional status. (2010) (44)
Human aging is associated with parallel reductions in insulin and amylin release. (1998) (44)
Proteoglycans synthesized and secreted by pancreatic islet β-cells bind amylin (2003) (44)
Insulin Resistance is the Best Predictor of the Metabolic Syndrome in Subjects With a First‐Degree Relative With Type 2 Diabetes (2010) (44)
Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons. (1991) (44)
Identification of the Amyloid-Degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis (2007) (43)
Rosiglitazone Decreases C-Reactive Protein to a Greater Extent Relative to Glyburide and Metformin Over 4 Years Despite Greater Weight Gain (2009) (42)
beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes. (2000) (42)
The relative associations of β-cell function and insulin sensitivity with glycemic status and incident glycemic progression in migrant Asian Indians in the United States: the MASALA study. (2014) (42)
Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS) (2019) (42)
Impact of intra-abdominal fat and age on insulin sensitivity and beta-cell function. (2004) (42)
FTO predicts weight regain in the Look AHEAD Clinical Trial (2013) (42)
Defects in β-Cell Function and Insulin Sensitivity in Normoglycemic Streptozocin-Treated Baboons: A Model of Preclinical Insulin-Dependent Diabetes* (1988) (42)
Factors Affecting the Decline in Incidence of Diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS) (2014) (42)
Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: Rationale for the active-comparator CAROLINA trial (2013) (42)
Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation (2017) (41)
Diabetes Prevention Program (DPP) (2020) (41)
Hepatic Insulin Extraction in NAFLD Is Related to Insulin Resistance Rather Than Liver Fat Content. (2019) (41)
Ethnic differences in hepatic and systemic insulin sensitivity and their associated determinants in obese black and white South African women (2015) (41)
Plasma sterol evidence for decreased absorption and increased synthesis of cholesterol in insulin resistance and obesity. (2011) (41)
Changes in insulin sensitivity, glucose effectiveness, and B-cell function in regularly exercising subjects. (1995) (41)
Triglyceride response to an intensive lifestyle intervention is enhanced in carriers of the GCKR Pro446Leu polymorphism. (2011) (41)
Does diabetes prevention translate into reduced long-term vascular complications of diabetes? (2019) (40)
Insulin resistance in African-American and Caucasian women: differences in lipotoxicity, adipokines, and gene expression in adipose tissue and muscle. (2010) (40)
Gestational Diabetes or Lesser Degrees of Glucose Intolerance and Risk of Preeclampsia (2011) (40)
Change in Intra-Abdominal Fat Predicts the Risk of Hypertension in Japanese Americans (2015) (39)
Changes in Body Composition over Eight Years in a Randomized Trial of a Lifestyle Intervention: The Look AHEAD Study (2014) (38)
Proinsulin Levels Predict the Development of Non‐insulin‐dependent Diabetes Mellitus (NIDDM) in Japanese‐American Men (1996) (37)
Preventing diabetes--applying pathophysiological and epidemiological evidence. (2000) (37)
Low Plasma Adiponectin Concentrations Predict Increases in Visceral Adiposity and Insulin Resistance (2017) (37)
Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes (2000) (37)
PLTP activity decreases with weight loss: changes in PLTP are associated with changes in subcutaneous fat and FFA but not IAF or insulin sensitivity. (2003) (36)
Association of Thigh Muscle Mass with Insulin Resistance and Incident Type 2 Diabetes Mellitus in Japanese Americans (2018) (36)
Variation at the Melanocortin 4 Receptor gene and response to weight-loss interventions in the Diabetes Prevention Program (2013) (36)
Glucose stimulates and potentiates islet amyloid polypeptide secretion by the B-cell. (1991) (36)
Anticoagulation in Childhood-Onset Arterial Ischemic Stroke With Nonmoyamoya Arteriopathy: Findings From the Colorado and German (COAG) Collaboration (2009) (36)
Reduced gluteal expression of adipogenic and lipogenic genes in Black South African women is associated with obesity-related insulin resistance. (2011) (35)
Effect of Glucocorticoid and Growth Hormone Treatment on Proinsulin Levels in Humans (1993) (35)
Neprilysin Impedes Islet Amyloid Formation by Inhibition of Fibril Formation Rather Than Peptide Degradation* (2010) (35)
Diabetes: Insulin resistance and obesity (1999) (35)
The Look AHEAD Trial: Bone Loss at 4-Year Follow-up in Type 2 Diabetes (2014) (34)
Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program (2012) (34)
Peanut-allergic subjects and their peanut-tolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II. (2010) (34)
The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice (2003) (33)
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program (2012) (33)
Glucose- and time-dependence of islet amyloid formation in vitro. (2007) (33)
Exploring residual risk for diabetes and microvascular disease in the Diabetes Prevention Program Outcomes Study (DPPOS) (2017) (33)
Effects of Linagliptin on Cardiovascular and Kidney Outcomes in People With Normal and Reduced Kidney Function: Secondary Analysis of the CARMELINA Randomized Trial (2020) (32)
Novel approaches to restore beta cell function in prediabetes and type 2 diabetes (2018) (32)
Consent for genetics studies among clinical trial participants: findings from Action for Health in Diabetes (Look AHEAD) (2006) (32)
A variation at position -30 of the beta-cell glucokinase gene promoter is associated with reduced beta-cell function in middle-aged Japanese-American men. (1996) (31)
Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study (2018) (31)
The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets (2016) (31)
Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial (2020) (31)
Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants (2015) (31)
Mechanisms for hyperglycemia in type II diabetes mellitus: therapeutic implications for sulfonylurea treatment--an update. (1991) (30)
Matrix Metalloproteinase-9 Reduces Islet Amyloid Formation by Degrading Islet Amyloid Polypeptide* (2012) (30)
Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure (2017) (29)
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2* (2015) (28)
Midcourse correction to a clinical trial when the event rate is underestimated: the Look AHEAD (Action for Health in Diabetes) Study (2012) (26)
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells. (2000) (26)
Human Cardiovascular Disease IBC Chip-Wide Association with Weight Loss and Weight Regain in the Look AHEAD Trial (2013) (26)
Des-(27-31)C-Peptide (1996) (25)
Effects of short-term experimental insulin resistance and family history of diabetes on pancreatic beta-cell function in nondiabetic individuals. (2005) (25)
Serum ferritin is associated with non-alcoholic fatty liver disease and decreased Β-cell function in non-diabetic men and women. (2014) (25)
Reduced beta-cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding. (1999) (25)
The "parallel-cohort RCT": Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism. (2010) (24)
Adipocytokines as features of the metabolic syndrome determined using confirmatory factor analysis. (2013) (24)
Transgenic overproduction of islet amyloid polypeptide (amylin) is not sufficient for islet amyloid formation. (1997) (24)
Beta cell failure: causes and consequences. (2001) (23)
The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function. (2014) (23)
Latent class analysis of the metabolic syndrome. (2010) (22)
Intra-abdominal fat accumulation is greatest at younger ages in Japanese-American adults. (2010) (22)
Effect of sulfonylurea withdrawal on proinsulin levels, B cell function, and glucose disposal in subjects with noninsulin-dependent diabetes mellitus. (1996) (22)
Effects of exercise and nutrition on memory in Japanese Americans with impaired glucose tolerance. (2006) (22)
Association of the SLC30A8 missense polymorphism R325W with proinsulin levels at baseline and after lifestyle, metformin or troglitazone intervention in the Diabetes Prevention Program (2011) (22)
Subcutaneous thigh fat area is unrelated to risk of type 2 diabetes in a prospective study of Japanese Americans (2011) (21)
Differential Association Between HDL Subclasses and the Development of Type 2 Diabetes in a Prospective Study of Japanese Americans (2015) (21)
The Incidence of Diabetes Among 2,777,768 Veterans With and Without Recent SARS-CoV-2 Infection (2022) (20)
An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants (2018) (20)
Confirming glycemic status in the Diabetes Prevention Program: implications for diagnosing diabetes in high risk adults. (2013) (20)
Quantifying β-Cells in Health and Disease: The Past, the Present, and the Need (2012) (20)
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial (2015) (19)
A call for improved reporting of human islet characteristics in research articles (2018) (19)
Maternal Physical Activity and Insulin Action in Pregnancy and Their Relationships With Infant Body Composition (2013) (19)
Chronic kidney disease attenuates the plasma metabolome response to insulin. (2018) (19)
Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy. (2008) (19)
Impact of differences in glucose tolerance on the prevalence of a negative insulinogenic index. (2013) (19)
Reliability of error estimates from the minimal model: implications for measurements in physiological studies. (1994) (19)
The glucose intolerance of aging. Implications for intervention. (1991) (18)
Determination of Optimal Sample Size for Quantification of β-Cell Area, Amyloid Area and β-Cell Apoptosis in Isolated Islets (2015) (18)
β‐Cell Dysfunction in Type 2 Diabetes (2003) (18)
Population approaches to estimate minimal model indexes of insulin sensitivity and glucose effectiveness using full and reduced sampling schedules. (2006) (17)
Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation (2017) (17)
Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid. (1999) (17)
Rosiglitazone Decreases C-Reactive Protein to a Greater Extent Relative to Glyburide and Metformin over Four-Years in Spite of Greater Weight Gain: Observations from ADOPT (A Diabetes Outcome Progression Trial) (2009) (17)
Plasma pancreatic polypeptide levels are associated with differences in body fat distribution in human subjects (2007) (17)
A Call for Improved Reporting of Human Islet Characteristics in Research Articles (2018) (17)
Diabetes autoantibodies do not predict progression to diabetes in adults: the Diabetes Prevention Program (2014) (16)
Interactions between genetic background, insulin resistance and β‐cell function (2012) (16)
Neprilysin Deficiency Protects Against Fat-Induced Insulin Secretory Dysfunction by Maintaining Calcium Influx (2013) (16)
Metabolic Clusters and Outcomes in Older Adults: The Cardiovascular Health Study (2018) (16)
Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study (2020) (15)
Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention (2017) (15)
Glucose control in type 2 diabetes: still worthwhile and worth pursuing. (2009) (15)
Superiority of the Modification of Diet in Renal Disease equation over the Cockcroft-Gault equation in screening for impaired kidney function in Japanese Americans. (2007) (15)
Physical activity and metabolic health in chronic kidney disease: a cross-sectional study (2016) (15)
Glucokinase Gene Variations in Japanese-Americans With a Family History of NIDDM (1994) (15)
Human aging is associated with parallel reductions in insulin and amylin release. (1998) (15)
Endogenous somatostatin-28 modulates postprandial insulin secretion. Immunoneutralization studies in baboons. (1997) (14)
Genetic Ancestry Markers and Difference in A1c Between African American and White in the Diabetes Prevention Program (2018) (14)
SGLT2 Inhibitors-Sweet Success for Diabetic Kidney Disease? (2017) (13)
Effects of Intensive Lifestyle Intervention on All-Cause Mortality in Older Adults With Type 2 Diabetes and Overweight/Obesity: Results From the Look AHEAD Study. (2022) (13)
Baseline Predictors of Glycemic Worsening in Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study (2021) (13)
- Cell Glucokinase Deficiency and Hyperglycemia Are Associated With Reduced Islet Amyloid Deposition in a Mouse Model of Type 2 Diabetes (2000) (13)
Transgenic mice overproducing islet amyloid polypeptide have increased insulin storage and secretion in vitro (1994) (13)
Baseline Predictors of Glycemic Worsening in Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study (2021) (13)
Prior Glucose-Lowering Medication Use and 30-Day Outcomes Among 64,892 Veterans With Diabetes and COVID-19 (2021) (13)
Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice. (2005) (12)
Short Report: Circulating microRNAs are associated with incident diabetes over 10 years in Japanese Americans (2020) (12)
Effect of exercise training on insulin sensitivity, hyperinsulinemia and ectopic fat in black South African women: a randomized controlled trial. (2020) (12)
Management of patients with diabetic hyperlipidemia. (2003) (12)
Evidence for selective release of rodent islet amyloid polypeptide through the constitutive secretory pathway (1993) (12)
Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes. (1988) (12)
Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin. (2003) (11)
Arm length is associated with type 2 diabetes mellitus in Japanese-Americans (2012) (11)
Regulation of Insulin Secretion in Vivo (2001) (11)
Medications for type 2 diabetes: how will we be treating patients in 50 years? (2015) (11)
35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
Comparison of the Use of Reserpine Versus Alpha‐methyldopa for Second Step Treatment of Hypertension in the Elderly (1985) (11)
β‐cells in youth with impaired glucose tolerance or early type 2 diabetes secrete more insulin and are more responsive than in adults (2020) (10)
Prospective evaluation of β-cell function in insulin antoantibody-positive relatives of insulin-dependent diabetic patients☆ (1993) (10)
Effects of combination of change in visceral fat and thigh muscle mass on the development of type 2 diabetes. (2017) (10)
Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes. (2022) (10)
Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity* (2015) (10)
Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes. (2022) (10)
Type 2 Diabetes Subgroups, Risk for Complications, and Differential Effects Due to an Intensive Lifestyle Intervention (2021) (10)
Obstructive Sleep Apnea, Glucose Tolerance, and β-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study (2021) (10)
Greater visceral abdominal fat is associated with a lower probability of conversion of prehypertension to normotension (2017) (9)
Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes. (2022) (9)
OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function (2021) (9)
Relationships of the early insulin secretory response and oral disposition index with gastric emptying in subjects with normal glucose tolerance (2017) (9)
Engineering a new beta-cell: a critical venture requiring special attention to constantly changing physiological needs. (2004) (9)
Suppression of Beta-cell secretion by somatostatin does not fully reverse the disproportionate proinsulinemia of type 2 diabetes. (2004) (9)
The β Cell in Diabetes: Integrating Biomarkers with Functional Measures. (2021) (9)
Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women (2014) (9)
A Lesson From 2020: Public Health Matters for Both COVID-19 and Diabetes. (2020) (9)
Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors (2019) (8)
Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort (2020) (8)
Association Between Change in Accelerometer-Measured and Self-Reported Physical Activity and Cardiovascular Disease in the Look AHEAD Trial. (2022) (7)
What Geriatricians Should Know About Diabetes Mellitus (1990) (7)
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673–686 (2015) (7)
Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro (2020) (7)
Design and validation of a novel estimator of visceral adipose tissue area and comparison to existing adiposity surrogates. (2018) (7)
Long-term metformin adherence in the Diabetes Prevention Program Outcomes Study (2020) (7)
Usefulness of serum endothelin levels in predicting death and myocardial infarction but not coronary progression in postmenopausal women with coronary disease (from the Women's Angiographic Vitamin and Estrogen [WAVE] study). (2005) (7)
Rosiglitazone Associated Fractures in Type 2 Diabetes: An Analysis From ADOPT (2008) (7)
Change in visceral adiposity is an independent predictor of future arterial pulse pressure (2018) (7)
A novel risk classification paradigm for patients with impaired glucose tolerance and high cardiovascular risk. (2013) (7)
Metabolic and cardiopulmonary responses of older wheelchair-dependent and ambulatory patients during locomotion. (1983) (7)
Impaired counterregulatory responses to hypoglycaemia following oral glucose in adults with cystic fibrosis (2020) (7)
Inhibition of Insulin-Degrading Enzyme Does Not Increase Islet Amyloid Deposition in Vitro. (2016) (6)
Within-Trial Cost-Effectiveness of a Structured Lifestyle Intervention in Adults With Overweight/Obesity and Type 2 Diabetes: Results From the Action for Health in Diabetes (Look AHEAD) Study. (2020) (6)
Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice (2018) (6)
Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD (2015) (6)
Higher High Density Lipoprotein 2 (HDL2) to Total HDL Cholesterol Ratio Is Associated with a Lower Risk for Incident Hypertension (2018) (6)
Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice. (2001) (6)
Nateglinide increases first phase insulin secretion and enhances glucose clearance in type 2 diabetes (2000) (6)
Remnant-like lipoproteins, hormone therapy, and angiographic and clinical outcomes: the Women's Angiographic Vitamin & Estrogen Trial. (2004) (6)
Islet Autoimmunity is Highly Prevalent and Associated With Diminished β-Cell Function in Patients With Type 2 Diabetes in the Grade Study. (2022) (6)
An Oral Disposition Index Predicts the Development of Future Diabetes Above and Beyond Fasting and 2-Hour Glucose Levels Short title: Oral Disposition Index Predicts Diabetes (2008) (6)
The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience (2022) (5)
Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice. (2019) (5)
P3-012 Effects of rosiglitazone treatment on serum amyloid-beta 1–40 and 1–42 in patients with early Alzheimer's disease (2004) (5)
Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide. (2004) (5)
Withdrawal of medications leads to worsening of OGTT parameters in youth with impaired glucose tolerance or recently‐diagnosed type 2 diabetes (2020) (5)
History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial (2020) (5)
O4-05-05 Rosiglitazone preserves cognitive functions in patients with early Alzheimer's disease (2004) (5)
Predictors of Incident Type 2 Diabetes Mellitus in Japanese Americans with Normal Fasting Glucose Level (2018) (5)
Probing the Meaning of Persistent Propeptide Release in Type 1 Diabetes (2019) (5)
Minimum Waist and Visceral Fat Values for Identifying Japanese Americans at Risk for the Metabolic Syndrome (2007) (5)
Diabetes Care: “Taking It to the Limit One More Time” (2016) (5)
Associations of statin use with 30-day adverse outcomes among 4 801 406 US Veterans with and without SARS-CoV-2: an observational cohort study (2022) (5)
Withdrawal of medications leads to worsening of OGTT parameters in youth with impaired glucose tolerance or recently‐diagnosed type 2 diabetes (2020) (5)
Sex‐related differences in cognitive trajectories in older individuals with type 2 diabetes and overweight or obesity (2021) (5)
Hyperglucagonemia Does Not Explain the β-Cell Hyperresponsiveness and Insulin Resistance in Dysglycemic Youth Compared With Adults: Lessons From the RISE Study (2021) (5)
Differential Loss of β-cell Function in Youth vs. Adults Following Treatment Withdrawal in the Restoring Insulin Secretion (RISE) Study. (2021) (5)
Effect of linagliptin versus placebo on cardiovascular and kidney outcomes in nephrotic-range proteinuria and type 2 diabetes: the CARMELINA randomized controlled trial (2021) (5)
Erratum to: Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials (2012) (4)
Chronic kidney disease and obesity bias surrogate estimates of insulin sensitivity compared with the hyperinsulinemic euglycemic clamp. (2017) (4)
NWP-Initialized Satellite Temperature Retrievals Using Statistical Regularization and Singular Value Decomposition Methods (1994) (4)
Change in CT-Measured Abdominal Subcutaneous and Visceral but Not Thigh Fat Areas Predict Future Insulin Sensitivity. (2019) (4)
Intra-abdominal fat is a major contributor to insulin sensitivity in both lean and obese subjects (1999) (4)
Association of glycemia with insulin sensitivity and β-cell function in adults with early type 2 diabetes on metformin alone. (2021) (4)
Consequences of human IAPP expression in transgenic mice (1996) (4)
Legacy of a 10-Year Multidomain Lifestyle Intervention on the Cognitive Trajectories of Individuals with Overweight/Obesity and Type 2 Diabetes Mellitus (2021) (4)
Regression from Pre-diabetes to Normal Glucose Regulation is Associated with Long-term Reduction in Diabetes Risk: Results from the Diabetes Prevention Program Outcomes Study (2013) (4)
Shape of the OGTT glucose response curve: relationship with β-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin (2021) (4)
The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS) (2022) (3)
Intra-Abdominal Fat and High Density Lipoprotein Cholesterol Are Associated in a Non-Linear Pattern in Japanese-Americans (2020) (3)
Response to Comment on Cefalu et al. Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum. Diabetes Care 2016;39:1186–1201 (2017) (3)
Leptin and Adiponectin Concentrations Independently Predict Future Accumulation of Visceral Fat in Nondiabetic Japanese Americans (2020) (3)
Comparison of twenty indices of insulin sensitivity in predicting type 2 diabetes in Japanese Americans: The Japanese American Community Diabetes Study. (2020) (3)
Normal Insulin Secretion in Humans (2003) (3)
Big Topics for Diabetes Care in 2018: Clinical Guidelines, Costs of Diabetes, and Information Technology (2018) (3)
The duodenal glucose load impacts the oral disposition index in healthy subjects (2015) (3)
Islet Autoimmunity in Adults With Impaired Glucose Tolerance and Recently Diagnosed, Treatment Naïve Type 2 Diabetes in the Restoring Insulin SEcretion (RISE) Study (2021) (3)
Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics (2022) (3)
What's Next for Diabetes Prevention? (2011) (3)
Glucose control, macro- and microvascular disease, and the Food and Drug Administration: let's keep our eye on the ball. (2008) (3)
Cancer and All-Cause Mortality: Meta-Analysis of Randomised Clinical Trials of Metformin (2011) (3)
Apolipoprotein B Levels Predict Future Development of Hypertension Independent of Visceral Adiposity and Insulin Sensitivity (2020) (3)
Anti-Xa Stability of Diluted Dalteparin for Pediatric Use (2008) (3)
The Impact of a Statewide Stroke Quality Improvement Program: Colorado Stroke Alliance and Colorado Stroke Registry (2011) (3)
RNA-seq-based identification of Star upregulation by islet amyloid formation. (2019) (3)
Reduced b -cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding (1999) (3)
Association Between the 4 bp Proinsulin Gene Insertion Polymorphism (IVS‐69) and Body Composition in Black South African Women (2009) (3)
Nutrition and inflammation: role of dietary cholesterol (2004) (2)
Abstracts of the 49th Annual Meeting of the EASD (2013) (2)
Effect of a Long-Term Behavioral Weight Loss Intervention on Nephropathy in Overweight or Obese Adults with Type 2 Diabetes: the Look AHEAD Randomized Clinical Trial (2015) (2)
Effect of Medical and Surgical Interventions on α-Cell Function in Dysglycemic Youth and Adults in the RISE Study (2021) (2)
Changes in mood and health‐related quality of life in Look AHEAD 6 years after termination of the lifestyle intervention (2021) (2)
On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes: Reply to Johnson JD [letter] (2021) (2)
The pathophysiologic defects of type 2 diabetes. Abnormal insulin action and impaired insulin secretion. (2000) (2)
Daniel Porte Jr.: A Leader in Our Understanding of the Role of Defective Insulin Secretion and Action in Obesity and Type 2 Diabetes (2020) (2)
Beta cell failure (2001) (2)
Use of Mediation in Designing Clinical Trials with two Primary Endpoints (2009) (2)
Depressive Symptoms in Pulmonary Arterial Hypertension: Prevalence and Impact on Functional Status. (2009) (2)
RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity (2022) (2)
Hepatic Fat in Participants With and Without Incident Diabetes in the Diabetes Prevention Program Outcome Study (2021) (2)
Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study (2021) (2)
156 INCREASED VISCERAL ADIPOSITY IS ASSOCIATED WITH DECREASED GLOMERULAR FILTRATION RATE BY A MECHANISM INDEPENDENT OF GLUCOSE TOLERANCE. (2006) (2)
Proinsulin/insulin ratio reduced and β-cell function improved in type 2 diabetes with rosiglitazone (2000) (2)
SGLT 2 Inhibitors — Sweet Success for Diabetic Kidney Disease ? (2016) (2)
Erratum: Steroid sex hormones, sex hormone binding globulin, and diabetes incidence in the diabetes prevention program (The Journal of Clinical Endocrinology & Metabolism (2015) 100:10 (3778-3786) DOI: 10.1210/jc.2015-2328) (2015) (2)
Lower High-Density Lipoprotein Cholesterol Concentration Is Independently Associated with Greater Future Accumulation of Intra-Abdominal Fat (2021) (2)
β-cell function in black South African women: exploratory associations with insulin clearance, visceral and ectopic fat (2021) (2)
ADOPT: The effectiveness of metformin versus glyburide in type 2 diabetes (2007) (1)
28-OR: Identification of Ancestry-Specific Alleles in a Genome-Wide Association Study (GWAS) for Metformin (MET) Response in the Diabetes Prevention Program (DPP) (2021) (1)
Adiposity, related biomarkers, and type 2 diabetes after gestational diabetes: The Diabetes Prevention Program (2021) (1)
Precision and Accuracy of Hyperglycemic Clamps in a Multicenter Study. (2021) (1)
Pancreatic morphology in normal and diabetic states (2015) (1)
Differences inCardiovascular Responses to Isoproterenol inRelation toAgeandExercise Training inHealthy Men (2011) (1)
Commentary: Of HOPEs and DREAMs: the quest to prevent type 2 diabetes. (2006) (1)
124-OR: Comparison of OGTT Model-Derived Measures of ß-Cell Function between Youth and Adults (2019) (1)
Insulin resistance and beta cell dysfunction: a dual therapeutic approach. (2002) (1)
PLTP activity decreases with weight loss Published, JLR Papers in Press, July 1, 2003. DOI 10.1194/jlr.M300073-JLR200 (2003) (1)
Michaela Diamant, 11 April 1962–9 April 2014 (2014) (1)
124-OR: Comparison of OGTT Model-Derived Measures of ß-Cell Function between Youth and Adults (2019) (1)
Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice (2022) (1)
Plasminogen activator inhibitor-1 (PAI-1) and c-reactive protein (CRP) comprise integral components of the metabolic syndrome (2012) (1)
3P-0902 Dyslipidemia of insulin resistance and obesity: Gender differences (2003) (1)
Genetic Architecture of Plasma Alpha‐Aminoadipic Acid Reveals a Relationship With High‐Density Lipoprotein Cholesterol (2022) (1)
Genetic Score Based on 34 Con fi rmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program (2011) (1)
Preeclampsia and Risk of Developing Subsequent (2009) (1)
Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668–1677 (2018) (1)
Association of cognition with leptin and vascular endothelial growth factor in individuals with type 2 diabetes mellitus (2022) (1)
Natural history of impaired glucose tolerance in Japanese Americans: Change in visceral adiposity is associated with remission from impaired glucose tolerance to normal glucose tolerance. (2018) (1)
Insulin action and beta-cell function : role in metabolic regulation (2010) (1)
P6272First plus recurrent CV and hospitalization events in the CArdiovascular and Renal Microvascular outcomE study with LINAgliptin (CARMELINA) in patients with type 2 diabetes and cardiorenal disease (2019) (1)
Plasma amino acid profile, a biomarker for visceral adipose tissue that can substitute for waist circumference in Japanese Americans. (2021) (1)
Understanding the Basis of Biologic Variance in the Obesity/Diabetes/Cardiovascular Disease Connection Obesity, Body Fat Distribution, Insulin Sensitivity and Islet b -Cell Function as Explanations for Metabolic Diversity 1,2 (2001) (1)
Sex‐related differences in cognitive trajectories in older individuals with type 2 diabetes and overweight or obesity and the role of APOE4: Findings from the Look AHEAD and Look AHEAD‐MIND studies (2020) (1)
Tubular Secretory Clearance is Associated with Whole-Body Insulin Clearance. (2020) (1)
432-P: Analyses of First plus Recurrent Cardiovascular and Hospitalization Events in the Cardiovascular and Renal Microvascular Outcome Study with Linagliptin (CARMELINA) in Patients with Type 2 Diabetes and Cardiorenal Disease (2019) (1)
Levels of beta-cell dysfunction and insulin resistance differ between Europeans and North Americans with recently-diagnosed diabetes in the ADOPT study (2003) (1)
Supplemental Tables 1-6 for "Tubular Secretory Clearance is Associated with Whole-Body Insulin Clearance" (2020) (1)
Greater reductions in C-reactive protein with rosiglitazone than with glyburide or metformin despite greater weight gain (2007) (1)
Identification of Genetic Variation Influencing Metformin Response in a Multi-Ancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP). (2022) (1)
Metabolic Function in 5,047 Adults with Type 2 Diabetes on Metformin Alone Based on Oral Glucose Tolerance Test (OGTT) Data from the GRADE Cohort (2018) (0)
1679-P: Islet Autoimmunity in Adults with Impaired Glucose Tolerance (IGT) and Newly Diagnosed, Treatment-Naïve Type 2 Diabetes (NDX T2D) in the Restoring Insulin Secretion (RISE) Study (2020) (0)
478: Women with gestational diabetes or lesser degrees of glucose intolerance have a greater risk of preeclampsia (2007) (0)
Treatment with thiazolidinediones (2013) (0)
69 Candidate genes in non-insulin-dependent diabetes mellitus (1997) (0)
226-LB: HOMA-ß and ß-Cell Activity in Early and Late Phase during an OGTT Are Independent Risk Factors of Type 2 Diabetes in Japanese Americans (2019) (0)
JNK inhibition protects the ß-cell from amyloid induced apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets (2010) (0)
Amyloid-induced oxidative stress contributes to reduced islet cell viability but does not impact insulin secretion (2007) (0)
The Art of Diabetes Care. (2023) (0)
2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide (2019) (0)
Assessment of Circulating Insulin Using Mass Spectrometry During Insulin Glargine Treatment in Type 2 Diabetes: Implications for Estimating Insulin Sensitivity and β-cell Function. (2023) (0)
cut points to screen asian americans for type 2 diabetes. (2015) (0)
Does the Shape of the OGTT Glucose Curve Reflect Metabolic Function in Individuals with Type 2 Diabetes? Baseline Data from the GRADE Cohort (2018) (0)
341-OR: Enhanced Responsiveness of ß- and α-Cells to Glucagon-Like Peptide-1 (GLP-1) in Youth vs. Adults with Impaired Glucose Tolerance (IGT) or Drug-Naïve Type 2 Diabetes (T2D) (2022) (0)
122-OR: Impact of Withdrawal of Interventions in the Restoring Insulin Secretion (RISE) Pediatric Medication Study (2019) (0)
Inhibition of matrix metalloproteinases increases islet amyloid deposition in vitro (2008) (0)
Reproducibility of Glycemic Measures among Dysglycemic Youth and Adults in the RISE Study. (2023) (0)
Amyloid formation in isolated islets is not associated with endoplasmic reticulum (ER) stress (2007) (0)
β-cell function in black South African women: Associations with insulin clearance and ectopic fat (2020) (0)
294-OR: RIPK3-Mediated Necroptosis Is an Alternative Form of TNFa-Induced ß-Cell Death (2021) (0)
Short Report: Circulating microRNAs are associated with incident diabetes over 10 years in Japanese Americans (2020) (0)
1320-P: Baseline Predictors of Change in Glycemia in the Restoring Insulin Secretion (RISE) Pediatric Medication Study (2019) (0)
1794-P: Successful Standardization of a Hyperglycemic Clamp Method across Multiple Clinical Centers in the Restoring Insulin Secretion (RISE) Study (2020) (0)
361-OR: Proinsulin Processing Efficiency Differs in Youth and Adults with IGT or Untreated T2D (2022) (0)
1826-P: Comparison of OGTT-Model Measures with the Hyperglycemic Clamp in Youth and Adults with IGT or Early Type 2 Diabetes (DM) (2019) (0)
Pathophysiology of islet dysfunction in non-insulin-dependent (Type II) diabetes mellitus (1989) (0)
Up Front (2018) (0)
952-P: Incident and Recurrent Hypoglycemia with Linagliptin and Glimepiride in the CAROLINA Trial (2020) (0)
High Frequency of Unrecognized Diabetes in Cardiovascular Patients: Should All Have an Oral Glucose Tolerance Test? (2008) (0)
Increased incidence of fractures in women who received rosiglitazone in ADOPT (A Diabetes Outcome Progression Trial) (2007) (0)
Advances in diabetes management: Application to the geriatric patient (2000) (0)
CD4-A β-cell function and volume in the development of Type 2 diabetes (2008) (0)
249-OR: Type 2 Diabetes (T2D) Genetic Clusters for Association with Glycemic Responses to Intervention for Diabetes Prevention (2021) (0)
1324-P: Short-Term Effects of Glycemia-Lowering Medications on ß-Cell Function in the GRADE Study (2022) (0)
1216-P: Plasma Amino Acid Profile as a Predictive Biomarker for Visceral Adiposity in Japanese Americans (2021) (0)
HOT TOPIC Islet Amyloid: A Critical Entity in the Pathogenesis of Type 2 Diabetes (2004) (0)
Upregulation of the amyloid-degrading enzyme, neprilysin, results in decreased amyloid and apoptosis in islets from human islet amyloid polypeptide (hIAPP) transgenic mice (2009) (0)
Erratum to: Effect of linagliptin versus placebo on cardiovascular and kidney outcomes in nephrotic-range proteinuria and type 2 diabetes (t2d): the carmelina randomised controlled trial (2021) (0)
Relationship between Baseline Phenotype and Measures of Insulin Sensitivity and Beta-Cell Responses in the GRADE Cohort (2018) (0)
Weight loss and β‐cell responses following gastric banding or pharmacotherapy in adults with impaired glucose tolerance or type 2 diabetes: a randomized trial (2022) (0)
Tissue Plasminogen Activator (tPA) Expression Is Increased by Islet Amyloid Formation In Vitro (2018) (0)
2040-P: Chronic Activation of CREB by Islet Amyloid Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets (2020) (0)
Is the Long‐term Impact of a Multidomain Lifestyle Intervention on Cognitive Function Mediated by Changes in Leptin and Vascular Endothelial Growth Factor Concentrations? (2022) (0)
Loss of ARC worsens high fat diet-induced hyperglycemia in mice. (2021) (0)
Impact of Obstructive Sleep Apnea and Sleep Duration on Glucose Tolerance and Beta-Cell Function in Adults with Prediabetes or Untreated Type 2 Diabetes (2019) (0)
Leptin Concentration Predicts Future Metabolic Syndrome Risk in Japanese Americans Independent of Body Composition (2018) (0)
Glucocorticoid receptor [alpha] expression is downregulated in gluteal subcutaneous adipose tissue of black South African women and associates with increased metabolic risk (2012) (0)
Loss of beta cells occurs selectively in amyloid laden islets in human type 2 diabetes (2008) (0)
Islet amyloid formation is associated with activation of JNK but not p38 or NFKB in cultured human islet amyloid polypeptide transgenic mouse islets (2009) (0)
METABOLISM, ENDOCRINOLOGY AND DIABETES (MEND) RESEARCH CONFERENCE (2014) (0)
Suppression of-Cell Secretion by Somatostatin Does Not Fully Reverse the Disproportionate Proinsulinemia of Type 2 Diabetes (2004) (0)
167 EVIDENCE FOR A HYPERBOLIC RELATIONSHIP BETWEEN INSULIN SENSITIVITY AND THE INSULIN RESPONSE DERIVED FROM AN ORAL GLUCOSE TOLERANCE TEST (2005) (0)
Islet amyloid formation in humans is diffuse, involving the majority of islets before becoming severe and replacing b-cell mass (2004) (0)
1326-P: Baseline OGTT as a Predictor of Type 2 Diabetes Progression in the GRADE Study (2022) (0)
Erratum. Rationale and Design of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care 2013;36:2254-2261. (2022) (0)
Predictors of Incident Type 2 Diabetes Mellitus in Japanese Americans with Normal Fasting Glucose Level. (2018) (0)
Diabetes Research and Clinical Practice (2011) (0)
A history of having a macrosomic infant increases the risk of the metabolic syndrome, diabetes, and heart disease (2006) (0)
2124-P: The Tissue Plasminogen Activator (tPA)/Plasmin System Reduces Amyloid Formation by Cleaving Human Islet Amyloid Polypeptide (hIAPP) (2019) (0)
678: Preterm delivery is associated with future diabetes independent of preeclampsia or gestational diabetes (2007) (0)
Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP) (2022) (0)
Prospective evaluation of beta-cell function in insulin autoantibody-positive relatives of insulin-dependent diabetic patients. (1993) (0)
Changes in bone metabolism biomarkers in the ADOPT study (2008) (0)
Editorial Cycles and Continuity of Diabetes Care. (2022) (0)
"The Times They Are A-Changin'" at Diabetes Care. (2022) (0)
Reviews : Clinical Diabetes Mellitus: A Problem-Oriented Approach, 2d ed, edited by John K. Davidson (1991). Thieme Medical Publishers, Suite 1501, 381 Park Avenue South, New York, NY 10157-0208. 822 pages. Price: $149 (1992) (0)
155 THE EARLY INSULIN RESPONSE DURING AN ORAL GLUCOSE TOLERANCE TEST EXHIBITS MARKED DAY-TO-DAY VARIABILITY IN FREE-LIVING ADULTS. (2006) (0)
1296-P: Adipose Tissue Insulin Resistance in RISE: Divergence between Youth and Adults, and Females and Males (2022) (0)
1612-P: Insulinogenic Index and HOMA-ß Are Independent Risk Factors for Future Type 2 Diabetes (2019) (0)
2042-P: Loss of Apoptosis Repressor with Caspase Recruitment Domain Promotes High-Fat Diet Induced Hyperglycemia In Vivo (2020) (0)
2039-P: Plasmin-Mediated Cleavage of Human Islet Amyloid Polypeptide (hIAPP) Protects ß-Cells from Amyloid-Induced Toxicity (2020) (0)
Differential Effects of a bdominal a dipose t issue Distribution on Insulin s ensitivity in Black and White s outh a frican Women (2009) (0)
Genetic Predictors ofWeight Loss and Weight Regain After Intensive Lifestyle Modi fi cation , Metformin Treatment , or Standard Care in the Diabetes Prevention Program (2011) (0)
2057-P: HDL-Cholesterol Concentration Independently Predicts Future Accumulation of Intra-abdominal Fat in Japanese Americans (2019) (0)
2125-P: Increased StAR (Steroidogenic Acute Regulatory Protein) Is Detrimental to ß Cells and Promotes Mitochondrial Dysfunction (2019) (0)
1792-P: Measures of ß-Cell Function from Two-Step Hyperglycemic Clamps: Relation to Glycemia (2020) (0)
Evidence for Necroptosis as a Mechanism of Islet Amyloid–Induced Beta-Cell Death (2018) (0)
60-OR: OGTT Glucose Response Curves (GRC), Insulin Sensitivity (IS), and ß-Cell Function (ßCF) in RISE: Youth–Adult Contrast at Randomization and in Response to Interventions to Preserve ßCF (2020) (0)
Exendin-4 limits ß-cell apoptosis and loss of ß-cell area in amyloid-forming islets (2010) (0)
254-OR: Islet Autoimmunity Is Highly Prevalent and Associated with Diminished Beta-Cell Function in Patients with Type 2 Diabetes (T2D) in the GRADE Study (2020) (0)
The Rare and Atypical Diabetes Network (RADIANT) Study: Design and Early Results. (2023) (0)
Metabolic risk-factor profiles in infants in relation to those of their mothers during pregnancy (2011) (0)
Inhibition of the amyloid-degrading enzyme, neprilysin, results in increased amyloid in islets from human islet amyloid polypeptide (hIAPP) transgenic mice (2007) (0)
Reducing Bias in Academic Publishing: The Diabetes Care Approach. (2023) (0)
Abstract 1182: High Frequency of Unrecognized Diabetes in Cardiovascular Patients: Should All Have an Oral Glucose Tolerance Test? (2008) (0)
Amylin Release Decreases in Parallel with Insulin Release in Aging (1998) (0)
1457-P: Cholesterol Accumulation in Islets Increases Steroidogenic Acute Regulatory (StAR) Protein Expression and Decreases Islet Cell Viability and ß-Cell Function (2022) (0)
130-OR: Statin Exposure Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets: A Novel Mechanism for ß-Cell Dysfunction and Increased Diabetes Risk? (2021) (0)
AENDO October 40/4 (1999) (0)
P-206 Pioglitazone modulates plasma levels of β-amyloid in glucose intolerant older adults (2007) (0)
Correction to: Quantitative trait loci, G×E and G×G for glycemic traits: response to metformin and placebo in the Diabetes Prevention Program (DPP) (2018) (0)
Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668—1677 (2019) (0)
Clinical and Metabolic Characterization of Adults With Type 2 Diabetes by Age in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) Cohort (2022) (0)
Contents Vol. 75, 2013 (2013) (0)
Chronic free fatty acids but not glucose decrease matrix metalloproteinase-9 in islets (2011) (0)
Low birth weight among adults with a family history of diabetes decreases the risk of metabolic syndrome (2006) (0)
METABOLISM, ENDOCRINOLOGY AND DIABETES (MEND) CLINICAL CONFERENCE (2014) (0)
SUN-LB015 Baseline Characteristics and Effects on CV and Kidney Outcomes with Linagliptin Versus Placebo, Across GFR Categories in CARMELINA (2019) (0)
Modulating dietary fat and glycemic load affects CSF biomarkers and cognition in adults with MCI: The role of the Western diet in the pathophysiology of Alzheimer's disease (2010) (0)
Dietary Animal and Saturated Fat Predict Future Visceral Fat Accumulation in Japanese Americans (2018) (0)
Syddansk Universitet Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC 2 (2015) (0)
Perspectives in Diabetes Hyperproinsulinemia and Amyloid in NIDDM Clues to Etiology of Islet p-Cell Dysfunction ? (2006) (0)
Determinants of monotherapy failure in ADOPT - (A diabetes outcome progression trial) (2007) (0)
Minutes of the 21st General Assembly of the European Association for the Study of Diabetes (2004) (0)
Late‐breaking Trials (2006) (0)
2058-P: Leptin and Adiponectin Concentrations Independently Predict Future Accumulation of Visceral Adiposity in Nondiabetic Japanese Americans (2019) (0)
Pathogenesis: Obesity and Type 2 Diabetes (2011) (0)
Legacy of a 10‐year multidomain lifestyle intervention on the cognitive trajectories of overweight and obese individuals with type 2 diabetes mellitus (2020) (0)
Edinburgh Research Explorer Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT) rationale and design (2020) (0)
1268-P: Associations between ß-Cell Function and Cognitive Measures following Treatment in Youth with Impaired Glucose Tolerance (IGT) or Recently Diagnosed Type 2 Diabetes (T2D) (2020) (0)
Front & Back Matter (2013) (0)
240: Women with a history of preeclampsia have an atherogenic lipid profile and endothelial dysfunction but no difference in adiposity or insulin sensitivity (2008) (0)
Genetic Markers Explain Differences in HbA1c Levels between African-American (AA) and Non-Hispanic White (NHW) Participants of the Diabetes Prevention Program (DPP) (2018) (0)
290 THE AGE-RELATED INCREASE IN INTRA-ABDOMINAL FAT IS ASSOCIATED NOT ONLY WITH DECREASED INSULIN SENSITIVITY BUT ALSO WITH REDUCED β-CELL FUNCTION. (2004) (0)
1782-P: Impact of Treatment with Medication vs. Laparoscopic Gastric Banding (GB) on ß-Cell Function in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D) in the Restoring Insulin Secretion (RISE) Study (2020) (0)
Impact of Lifestyle Q : 1 and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation (2017) (0)
The concurrent deposition of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations in nonobese subjects (2002) (0)
Rosiglitazone treatment decreases amyloid formation following transplantation of human islet amyloid polypeptide (hIAPP) transgenic islets (2008) (0)
1779-P: Liraglutide + Metformin Delays Worsening of Glycemia in Adults with Impaired Glucose Tolerance (IGT) or Type 2 Diabetes (T2D) (2020) (0)
388-P: Interrelationship between Hypoglycemia and CV and Mortality Outcomes in Type 2 Diabetes in the CARMELINA Trial (2019) (0)
1119-P: Persistent and Heterogeneous Long-Term Effects of the Diabetes Prevention Program (DPP) Intensive Lifestyle (ILS) Intervention on Diabetes Incidence (2022) (0)
Phospholipid transfer protein activity decreases with weight loss: Changes in PLTP are associated with changes in subcutaneous fat and non-esterified fatty acids but not with intra- abdominal fat or insulin sensitivity. (2003) (0)
Inhibition of MMP-9 increases islet amyloid deposition and ß-cell apoptosis in human islet amyloid polypeptide transgenic mouse islets (2009) (0)
Response to Letter to the Editor: Hepatic insulin extraction in NAFLD is related to insulin resistance rather than liver fat content. (2019) (0)
258-OR: Sustainability of HbA1c Control of Tirzepatide vs. Insulin Glargine in People with Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4) (2022) (0)
318 INTRA-ABDOMINAL FAT PREDICTS FUTURE DEVELOPMENT OF THE METABOLIC SYNDROME IN NON-DIABETIC JAPANESE-AMERICANS (2005) (0)
Effects of truncated glucagon-like peptide 1 on insulin secretion, insulin sensitivity and glucose effectiveness in healthy humans (1993) (0)
291 PREDICTORS FOR INCREASED VISCERAL ADIPOSITY AT 10-YEAR FOLLOW-UP IN NON-DIABETIC JAPANESE-AMERICANS. (2004) (0)
326 PARASYMPATHETIC INNERVATION MAY MEDIATE THE EFFECT OF AGE AND GENDER ON BODY FAT DISTRIBUTION IN HUMANS. (2006) (0)
1261-P: OGTT Model–Derived ß-Cell Function Reveals Differential Loss in Youth vs. Adults during and following Treatment Withdrawal in the Restoring Insulin Secretion (RISE) Study (2020) (0)
1561-P: Associations between ß-Cell Function and Cognitive Measures Differ in Youth vs. Adults with Impaired Glucose Tolerance (IGT) or Early Type 2 Diabetes (T2D) (2019) (0)
Exploring the role of environmental factors in association and linkage studies (1999) (0)
122-OR: Impact of Withdrawal of Interventions in the Restoring Insulin Secretion (RISE) Pediatric Medication Study (2019) (0)
A Dosing Formula For INR-Targeted Plasma Transfusion In Bleeding Patients With Chronic Liver Disease (2011) (0)
1826-P: Comparison of OGTT-Model Measures with the Hyperglycemic Clamp in Youth and Adults with IGT or Early Type 2 Diabetes (DM) (2019) (0)
1320-P: Baseline Predictors of Change in Glycemia in the Restoring Insulin Secretion (RISE) Pediatric Medication Study (2019) (0)
Weight loss and β‐cell responses following gastric banding or pharmacotherapy in adults with impaired glucose tolerance or type 2 diabetes: a randomized trial (2022) (0)
Arginine Supplementation in Pulmonary Arterial Hypertension (PAH): Results of a Pilot RCT. (2009) (0)
Postmenopausal Hormone Therapy Is Associated With Atherosclerosis Progression in Women With Abnormal Glucose Tolerance Vascular Biology (2004) (0)
The Kids-DOTT Trial: Novel Aspects of the ‘Parallel Cohort RCT‘ Design and Its Application to the Investigation of Duration of Anticoagulant Therapy for Pediatric Venous Thromboembolism. (2009) (0)
The metabolic syndrome and coronary disease progression in the Women's Angiographic Vitamin and Estrogen Trial (2002) (0)
1268-P: Associations between ß-Cell Function and Cognitive Measures following Treatment in Youth with Impaired Glucose Tolerance (IGT) or Recently Diagnosed Type 2 Diabetes (T2D) (2020) (0)
1780-P: Differential Effects of Medications and Gastric Banding on OGTT-Modeled Measures of ß-Cell Function in Adults with IGT or Recent-Onset Type 2 Diabetes (T2D) (2020) (0)
1501-P: Reproducibility of Glycemic Measures among Youth and Adults with Impaired Glucose Tolerance (IGT) or Recently Diagnosed Type 2 Diabetes (T2D) in the Restoring Insulin Secretion (RISE) Study (2019) (0)

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