Steven M. Finkbeiner
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Biology
Steven M. Finkbeiner's Degrees
- PhD Neuroscience University of California, San Francisco
- Bachelors Biology University of California, San Diego
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(Suggest an Edit or Addition)Steven M. Finkbeiner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death (2004) (1968)
- Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear Inclusions (1998) (1644)
- Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism (1998) (1496)
- Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease (2007) (1314)
- CREB: A Major Mediator of Neuronal Neurotrophin Responses (1997) (925)
- Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies (2019) (871)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. (2002) (523)
- Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein*♦ (2011) (506)
- Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport (2010) (480)
- CREB Couples Neurotrophin Signals to Survival Messages (2000) (461)
- Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis (2010) (437)
- Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes. (2012) (431)
- Genome-wide Analyses Identify KIF5A as a Novel ALS Gene (2018) (414)
- Genome-wide Analyses Identify KIF5A as a Novel ALS Gene (2018) (414)
- In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images (2018) (404)
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome (2009) (369)
- Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models (2014) (354)
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability (2012) (326)
- Calcium waves in astrocytes-filling in the gaps (1992) (321)
- Therapeutic modulation of eIF2α-phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models (2013) (310)
- Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice (2009) (309)
- Protein aggregates in Huntington's disease (2012) (307)
- Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy (2013) (302)
- Arc in synaptic plasticity: from gene to behavior (2011) (296)
- Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease* (2010) (292)
- Ca2+-Dependent Routes to Ras: Mechanisms for Neuronal Survival, Differentiation, and Plasticity? (1996) (275)
- A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model (2010) (259)
- A comprehensive glossary of autophagy-related molecules and processes (2nd edition) (2011) (259)
- Ca2+ waves in astrocytes. (1991) (257)
- Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. (2012) (250)
- NMDA and AMPA receptors: old channels, new tricks (2007) (240)
- Potential function for the Huntingtin protein as a scaffold for selective autophagy (2014) (235)
- Arc regulates spine morphology and maintains network stability in vivo (2010) (231)
- Ca2+ channel-regulated neuronal gene expression. (1998) (212)
- Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models (2012) (207)
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. (2014) (205)
- Identifying polyglutamine protein species in situ that best predict neurodegeneration (2011) (195)
- AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc (2006) (189)
- Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration. (2013) (175)
- Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice (2017) (172)
- Rapid Target-Specific Remodeling of Fast-Spiking Inhibitory Circuits after Loss of Dopamine (2011) (162)
- Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease (2009) (160)
- Quantitative Relationships between Huntingtin Levels, Polyglutamine Length, Inclusion Body Formation, and Neuronal Death Provide Novel Insight into Huntington's Disease Molecular Pathogenesis (2010) (159)
- Mutant LRRK2 Toxicity in Neurons Depends on LRRK2 Levels and Synuclein But Not Kinase Activity or Inclusion Bodies (2014) (139)
- Targeting H3K4 trimethylation in Huntington disease (2013) (136)
- Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth (1999) (135)
- Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia (2019) (135)
- Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. (2009) (135)
- Arc in the nucleus regulates PML dependent GluA1 transcription and homeostatic plasticity (2013) (132)
- Automated microscope system for determining factors that predict neuronal fate. (2005) (126)
- Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research (2012) (126)
- Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease (2014) (122)
- Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System (2016) (118)
- Huntington's Disease. (2011) (113)
- Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease* (2009) (111)
- Assessing microscope image focus quality with deep learning (2018) (109)
- Identification of Novel Potentially Toxic Oligomers Formed in Vitro from Mammalian-derived Expanded huntingtin Exon-1 Protein* (2012) (103)
- Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 (2015) (103)
- Monoclonal Antibodies Recognize Distinct Conformational Epitopes Formed by Polyglutamine in a Mutant Huntingtin Fragment* (2009) (99)
- Calcium regulation of the brain-derived neurotrophic factor gene (2000) (98)
- Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis. (2017) (93)
- Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models (2012) (92)
- Mathematical Aspects of Hodgkin-Huxley Neural Theory (1988) (88)
- Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasis (2016) (86)
- Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor (2009) (84)
- The Serum Response Factor and a Putative Novel Transcription Factor Regulate Expression of the Immediate-Early Gene Arc/Arg3.1 in Neurons (2009) (82)
- The Autophagy Lysosomal Pathway and Neurodegeneration. (2019) (76)
- Splice Variants of the NR1 Subunit Differentially Induce NMDA Receptor-Dependent Gene Expression (2006) (76)
- The Ubiquitin-Proteasome Pathway in Huntington's Disease (2008) (73)
- Therapeutic use of magnesium sulfate in selected cases of cerebral ischemia and seizure. (1988) (71)
- Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases. (2016) (69)
- Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy (2015) (68)
- Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference (2014) (67)
- Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington’s Disease: Background and Evaluation in Cell Culture (2016) (62)
- Modeling Huntington's disease with induced pluripotent stem cells (2013) (61)
- Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism (2018) (59)
- The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein (2018) (59)
- Disease-Modifying Pathways in Neurodegeneration (2006) (58)
- Executive functions in premanifest Huntington's disease (2014) (58)
- A Compact β Model of huntingtin Toxicity* (2011) (56)
- Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. (2012) (56)
- Protein turnover and inclusion body formation (2009) (55)
- Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology. (2013) (52)
- Endothelin induces a sustained rise in intracellular calcium in hippocampal astrocytes (1991) (52)
- High-content screening of primary neurons: ready for prime time (2009) (51)
- Conformation sensors that distinguish monomeric proteins from oligomers in live cells. (2010) (51)
- Pathogenic TARDBP Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: Disease-Associated Pathways (2010) (48)
- Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties. (1989) (46)
- Bridging the Valley of Death of therapeutics for neurodegeneration (2010) (46)
- Proteostasis in striatal cells and selective neurodegeneration in Huntington’s disease (2014) (43)
- High-throughput screening in primary neurons. (2012) (42)
- Cross-species translation of the Morris maze for Alzheimer's disease. (2016) (42)
- Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis (2020) (40)
- Serine 421 regulates mutant huntingtin toxicity and clearance in mice. (2016) (40)
- Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology. (2016) (40)
- Spatial features of calcium-regulated gene expression. (1997) (38)
- Cell-Based Screening: Extracting Meaning from Complex Data (2015) (37)
- Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2018) (37)
- Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway (2019) (37)
- PolyQ Disease: Too Many Qs, Too Much Function? (2010) (36)
- SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells (2016) (35)
- Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines (2020) (35)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- iPS cells in the study of PD molecular pathogenesis (2018) (30)
- Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites (2019) (29)
- An evaluation of specificity in activity-dependent gene expression in neurons (2002) (29)
- Drug discovery in Parkinson's disease-Update and developments in the use of cellular models. (2011) (26)
- The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease. (2018) (26)
- αB-Crystallin overexpression in astrocytes modulates the phenotype of the BACHD mouse model of Huntington's disease. (2016) (26)
- Using antibodies to analyze polyglutamine stretches. (2004) (25)
- Crystallization and diffraction properties of the Fab fragment of 3B5H10, an antibody specific for disease-causing polyglutamine stretches. (2005) (23)
- Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease (2021) (22)
- Sequence-Level Analysis of the Major European Huntington Disease Haplotype. (2015) (22)
- Dexpramipexole Is Ineffective in Two Models of ALS Related Neurodegeneration (2014) (21)
- Identification of sixteen novel candidate genes for late onset Parkinson’s disease (2021) (21)
- New Roles for Introns: Sites of Combinatorial Regulation of Ca2+- and Cyclic AMP-Dependent Gene Transcription (2001) (17)
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. (2021) (16)
- Cell death assays for neurodegenerative disease drug discovery (2019) (15)
- Excitatory Amino Acid Transmission (1987) (15)
- An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients (2020) (14)
- An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients (2020) (14)
- Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells (2013) (14)
- PML in the Brain: From Development to Degeneration (2013) (14)
- Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration (2019) (14)
- Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information (2020) (14)
- Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes (2017) (13)
- Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins. (2013) (13)
- Neurotransmitter Interactions in the Basal Ganglia (1987) (13)
- Neurotrophins and the Synapse (1996) (13)
- Targeting the low-hanging fruit of neurodegeneration (2014) (13)
- LRP10 in α-synucleinopathies (2018) (13)
- To fear or not to fear: what was the question? A potential role for Ras-GRF in memory. (1998) (12)
- Superhuman cell death detection with biomarker-optimized neural networks (2020) (10)
- The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels* (2017) (10)
- Going Retro: Ancient Viral Origins of Cognition (2015) (9)
- Huntington’s disease mouse models: unraveling the pathology caused by CAG repeat expansion (2021) (9)
- Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration (2019) (8)
- Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration (2019) (8)
- Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries (2016) (8)
- A three‐groups model for high‐throughput survival screens (2016) (7)
- Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress. (2021) (7)
- NUB1 snubs huntingtin toxicity (2013) (6)
- Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells” (2013) (6)
- Common threads in neurodegenerative disorders of aging (2006) (6)
- Approaches to develop therapeutics to treat frontotemporal dementia (2020) (5)
- The Foundational data initiative for Parkinson’s disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism (2021) (5)
- Calcium-mediated Gene Expression: Mechanism for Neuronal Plasticity and Survival (1995) (5)
- A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems (2022) (5)
- RNA decay back in play (2007) (5)
- Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation (2021) (5)
- Secrets of a Secretase N-Cadherin Proteolysis Regulates CBP Function (2003) (4)
- The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity (2020) (4)
- Bringing SOD1 into the fold (2010) (4)
- Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data (2022) (3)
- Deubiquitinase Usp 12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington ’ s disease (2018) (3)
- Reply to Rubinsztein and Nixon: Potent and reliable autophagy induction in neurons (2010) (3)
- Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage (2021) (3)
- Opposing roles of p38α-mediated phosphorylation and arginine methylation in driving TDP-43 proteinopathy (2021) (3)
- Single cell transcriptomics of human PINK1 iPSC differentiation dynamics reveal a core network of Parkinson’s disease (2020) (2)
- Protein Folding and Misfolding in Health and Disease (2010) (2)
- Persistent mRNA Localization Defects and Cell Death in ALS Neurons Caused by Transient Cellular Stress (2020) (2)
- Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson's patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006). (2021) (2)
- Model Systems in Neurotoxicology: Alternate Approaches to Animal Testing (1988) (2)
- Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function (2020) (2)
- IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release (2020) (2)
- EFFECT OF MUTANT HUNTINGTIN ON STRIATAL NEURONS DIFFERENTIATED FROM HUNTINGTON’S DISEASE INDUCED PLURIPOTENT STEM CELLS (2011) (2)
- Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease (2020) (2)
- Faculty Opinions recommendation of In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. (2018) (1)
- Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease (2022) (1)
- Nuclear accumulation of host transcripts during Zika Virus Infection (2023) (1)
- UC San Francisco UC San Francisco Previously Published Works Title Modeling Huntington ' s disease with induced pluripotent stem cells (2013) (1)
- LONGITUDINAL IMAGING AND ANALYSIS OF TAU-EXPRESSING NEURONS (2014) (1)
- Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington’s Disease: Background and Evaluation in Cell Culture (2016) (1)
- Care of the Newborn. 2nd Edition (1988) (1)
- Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2020) (1)
- Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched (2021) (1)
- Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2020) (1)
- Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury (2022) (1)
- Generation of two human induced pluripotent stem cell lines from fibroblasts of Parkinson's disease patients carrying the ILE368ASN mutation in PINK1 (LCSBi002) and the R275W mutation in Parkin (LCSBI004). (2022) (1)
- A deep learning approach to neurite prediction in high throughput fluorescence imaging (2021) (1)
- Automated Robotic Microscopy System Combining Longitudinal Single Cell Image Analysis with High Throughput/ High Content Screening. INVENTORS (2013) (1)
- Genetic and Epigenetic Interplay Define Disease Onset and Severity in Repeat Diseases (2022) (1)
- Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2018) (1)
- High-Throughput RNA Interference as a Tool for Discovery in Neuroscience (2013) (1)
- Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects (2023) (1)
- Computational Cell-Barcoding for High-Throughput Robotic Microscopy (2017) (0)
- Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability (2019) (0)
- Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis (2023) (0)
- Molecular Biology in Basic and Clinical Neuroscience Research (1986) (0)
- The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism (2023) (0)
- Faculty Opinions recommendation of Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene. (0)
- Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information (2020) (0)
- A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway (2023) (0)
- Heart Failure and the Renin System: A Comprehensive Approach (1988) (0)
- AI Enabled Ensemble Deep Learning Method for Automated Sensing and Quantification of DNA Damage in Comet Assay (2023) (0)
- UC San Francisco UC San Francisco Previously Published Works Title Protein aggregates in Huntington ' s (2012) (0)
- Mechanisms of polyglutamine-dependent neurodegeneration revealed by automated imaging and structural approaches (2007) (0)
- Faculty Opinions recommendation of Cortical circuit alterations precede motor impairments in Huntington's disease mice. (0)
- Faculty Opinions recommendation of Therapeutic effects of stem cells in rodent models of Huntington's disease: Review and electrophysiological findings. (0)
- Faculty Opinions recommendation of Cortical network dynamics is altered in mouse models of huntington's disease. (0)
- Single cell tracking based on Voronoi partition via stable matching (2020) (0)
- Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2018) (0)
- JournaLog.™ (1989) (0)
- Faculty Opinions recommendation of PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease. (0)
- Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2020) (0)
- Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2020) (0)
- Faculty Opinions recommendation of Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice. (0)
- Faculty Opinions recommendation of Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. (0)
- Faculty Opinions recommendation of Fronto-striatal circuits for cognitive flexibility in far from onset Huntington's disease: evidence from the Young Adult Study. (0)
- Protein Kinase D as Novel Therapeutic Target for Neurological Disease (2010) (0)
- Predicting fates in models of neurodegenerative disease: longitudinal measures of protein homeostasis in live neurons (2013) (0)
- Huntington’s disease iPSC models—using human patient cells to understand the pathology caused by expanded CAG repeats (2022) (0)
- mTOR inhibitor-independent Autophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes (2022) (0)
- Small Molecule Inducers of Autophagy in Neurons (2010) (0)
- Ca++ waves in brain glial cells [Cells make a body, 2] (2016) (0)
- Small-Molecule Modulatio n of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS / FTD Graphical (2019) (0)
- NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency (2023) (0)
- TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A (2022) (0)
- Faculty Opinions recommendation of FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat. (0)
- Building a Medical Vocabulary. A Microcomputer Course. Building a Medical Vocabulary. A Microcomputer Review Course (1988) (0)
- Title Sequence-Level Analysis of the Major European Huntington Disease Haplotype Permalink (0)
- Boeing Graph. 3D Power Graphics v 2.0 (1988) (0)
- Faster Deep Ensemble Averaging for Quantification of DNA Damage from Comet Assay Images With Uncertainty Estimates (2021) (0)
- Faculty of 1000 evaluation for Stress granule assembly disrupts nucleocytoplasmic transport. (2018) (0)
- Faculty Opinions recommendation of Human neural stem cell transplantation rescues functional deficits in R6/2 and Q140 huntington's disease mice. (0)
- Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease (2018) (0)
- RMeDPower for Biology: guiding design, experimental structure and analyses of repeated measures data for biological studies (2022) (0)
- Protein Kinase D1 Regulates Synaptic Plasticity, Presenting a Novel Therapeutic Target for Neurological Disease. (2013) (0)
- Faculty Opinions recommendation of DNA repair in huntington's disease and spinocerebellar ataxias: somatic instability and alternative hypotheses. (0)
- Faculty Opinions recommendation of High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration. (2018) (0)
- Faculty Opinions recommendation of The cryo-electron microscopy structure of huntingtin. (0)
- Fluorescently labeled nuclear morphology is highly informative of neurotoxicity (2022) (0)
- Partitioning the genetic architecture of amyotrophic lateral sclerosis (2018) (0)
- Author response: Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells (2013) (0)
- Computer Assisted Medical Problem Solving (1988) (0)
- Faculty Opinions recommendation of Complete but not partial inhibition of glutamate transporters exacerbates cortical excitability in the R6/2 mouse model of Huntington's disease. (0)
- iPS cells in the study of PD molecular pathogenesis (2017) (0)
- Faculty Opinions recommendation of Integrative characterization of the R6/2 mouse model of huntington's disease reveals dysfunctional astrocyte metabolism. (0)
- Faculty Opinions recommendation of Striatal direct and indirect pathway output structures are differentially altered in mouse models of huntington's disease. (0)
- Protein-RNA Networks Re gulated by Normal and ALS-Associated Mutant HNRNPA 2 B 1 in the Nervous System Highlights (2016) (0)
- O4-03-01 Region specific alteration of hippocampal synaptic function in a mouse model of Alzheimer's disease (2004) (0)
- A11 Induced pluripotent stem cells for basic and translational research on HD (2012) (0)
- Title Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells (2013) (0)
- Faculty Opinions recommendation of Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model. (0)
- AutoComet: A fully automated algorithm to quickly and accurately analyze comet assays. (2023) (0)
- Dynamical Software (I.4.1) (1990) (0)
- Using the Past to Predict the Future: Applications of High Throughput Longitudinal Single Cell Analysis, Genomics, Stem Cells and Machine Learning to Discovery (2017) (0)
- Ripk 1 regulates progranulin levels 1 The Receptor-Interacting Serine / Threonine Protein Kinase 1 ( Ripk 1 ) Regulates Progranulin Levels (2016) (0)
- Faculty Opinions recommendation of Cortical morphometry and neural dysfunction in Huntington's disease: a review. (0)
- Measuring Autophagic Flux in Neurons by Optical Pulse Labeling (2021) (0)
- Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson’s disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007) (2021) (0)
- Faculty Opinions recommendation of Astrocytes in huntington's disease. (0)
- Neuron-Based High Throughput/High Content Screening (HTS/HCS) Platforms for Parkinson's Disease, Amyotrophic Lateral Sclerosis, Fronto-Temporal Dementia and Huntington's Disease. INVENTORS (2013) (0)
- Faculty Opinions recommendation of M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's disease. (0)
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