Steven Hahn
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Computer Science
Steven Hahn's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Steven Hahn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors (2009) (2421)
- Crystal structure of a yeast TBP/TATA-box complex (1993) (1010)
- Five intermediate complexes in transcription initiation by RNA polymerase II (1989) (863)
- Transcriptional regulation (2008) (816)
- Structure and mechanism of the RNA polymerase II transcription machinery (2004) (583)
- A Bacterial Effector Acts as a Plant Transcription Factor and Induces a Cell Size Regulator (2007) (564)
- The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. (1998) (533)
- Plant Pathogen Recognition Mediated by Promoter Activation of the Pepper Bs3 Resistance Gene (2007) (460)
- A transcription reinitiation intermediate that is stabilized by activator (2000) (433)
- Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. (1994) (318)
- Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators (2011) (303)
- An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression. (1984) (292)
- Function of a yeast TATA element-binding protein in a mammalian transcription system (1988) (268)
- Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae. (1985) (264)
- Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB. (1999) (246)
- Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators. (1999) (245)
- Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. (1989) (236)
- Yeast Nuclear Extract Contains Two Major Forms of RNA Polymerase II Mediator Complexes* (2001) (224)
- The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB (1992) (214)
- A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable (1988) (205)
- Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions (1989) (205)
- Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner (1987) (198)
- Two Cyclin-Dependent Kinases Promote RNA Polymerase II Transcription and Formation of the Scaffold Complex (2004) (194)
- Phosphorylation of the Transcription Elongation Factor Spt5 by Yeast Bur1 Kinase Stimulates Recruitment of the PAF Complex (2009) (193)
- Crystal Structure of the Yeast TFIIA/TBP/DNA Complex (1996) (183)
- The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex (2007) (180)
- Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters (1992) (177)
- A yeast TFIIB-related factor involved in RNA polymerase III transcription. (1992) (164)
- Transcriptional Activators of Human Genes with Programmable DNA-Specificity (2011) (163)
- The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. (2011) (158)
- An ATP-dependent inhibitor of TBP binding to DNA. (1993) (156)
- Identification of TFB5, a new component of general transcription and DNA repair factor IIH (2004) (156)
- SAGA is a general cofactor for RNA polymerase II transcription (2017) (137)
- Mapping the Location of TFIIB within the RNA Polymerase II Transcription Preinitiation Complex A Model for the Structure of the PIC (2004) (136)
- Targets of the Gal4 Transcription Activator in Functional Transcription Complexes (2005) (136)
- Binding of TFIIB to RNA polymerase II: Mapping the binding site for the TFIIB zinc ribbon domain within the preinitiation complex. (2003) (134)
- Structural insights into transcription initiation by RNA polymerase II. (2013) (133)
- Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening (2012) (127)
- Yeast HAP2 and HAP3: transcriptional activators in a heteromeric complex. (1988) (123)
- Isolation of two genes that encode subunits of the yeast transcription factor IIA. (1992) (121)
- Structure(?) and function of acidic transcription activators (1993) (121)
- Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID. (2017) (118)
- Function of a eukaryotic transcription activator during the transcription cycle. (2005) (117)
- Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles1[W] (2009) (117)
- The transcription elongation factor TFIIS is a component of RNA polymerase II preinitiation complexes (2007) (116)
- Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis (2007) (113)
- The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts (1988) (113)
- Detailed analysis of the DNA recognition motifs of the Xanthomonas type III effectors AvrBs3 and AvrBs3Deltarep16. (2009) (111)
- Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation (2015) (106)
- Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3. (2008) (105)
- Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex (2014) (105)
- Dominant negative mutations in yeast TFIID define a bipartite DNA-binding region (1991) (105)
- Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal and activated transcription (1995) (104)
- Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA (1997) (102)
- The yeast general transcription factor TFIIA is composed of two polypeptide subunits. (1991) (100)
- The Role of TAFs in RNA Polymerase II Transcription (1998) (100)
- Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex (2010) (95)
- Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. (2015) (90)
- Mechanism of Mediator Recruitment by Tandem Gcn4 Activation Domains and Three Gal11 Activator-Binding Domains (2010) (90)
- Model for binding of transcription factor TFIIB to the TBP-DNA complex (1995) (87)
- A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex (2006) (83)
- Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex (2018) (83)
- Domains of Tra1 Important for Activator Recruitment and Transcription Coactivator Functions of SAGA and NuA4 Complexes (2010) (82)
- Yeast Rrn7 and Human TAF1B Are TFIIB-Related RNA Polymerase I General Transcription Factors (2011) (78)
- Transcription: basal factors and activation. (1996) (76)
- A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface (2014) (74)
- Structure of human TFIID and mechanism of TBP loading onto promoter DNA (2018) (73)
- Positive and negative functions of the SAGA complex mediated through interaction of Spt8 with TBP and the N-terminal domain of TFIIA. (2004) (71)
- Upstream repression and CRP stimulation of the Escherichia coli L-arabinose operon. (1984) (71)
- RNA Polymerase II (Pol II)-TFIIF and Pol II-Mediator Complexes: the Major Stable Pol II Complexes and Their Activity in Transcription Initiation and Reinitiation (2004) (60)
- Activator-Independent Functions of the Yeast Mediator Sin4 Complex in Preinitiation Complex Formation and Transcription Reinitiation (2003) (59)
- The zinc ribbon domains of the general transcription factors TFIIB and Brf: conserved functional surfaces but different roles in transcription initiation. (2000) (59)
- Broad and efficient control of major foodborne pathogenic strains of Escherichia coli by mixtures of plant-produced colicins (2015) (58)
- Architecture of the Yeast RNA Polymerase II Open Complex and Regulation of Activity by TFIIF (2011) (57)
- Structure of human TFIID and mechanism of TBP loading onto promoter DNA. (2018) (56)
- Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters (2016) (56)
- Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA (2020) (55)
- Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA. (1989) (55)
- Transcription of Escherichia coli ara in vitro. The cyclic AMP receptor protein requirement for PBAD induction that depends on the presence and orientation of the araO2 site. (1986) (55)
- Architecture of Protein and DNA Contacts within the TFIIIB-DNA Complex (1998) (53)
- Cloning and Functional Characterization of the Gene Encoding the TFIIIB90 Subunit of RNA Polymerase III Transcription Factor TFIIIB* (1996) (52)
- The Yin and the Yang of mammalian transcription (1992) (50)
- A novel and fully scalable Agrobacterium spray-based process for manufacturing cellulases and other cost-sensitive proteins in plants. (2015) (49)
- Structure-system correlation identifies a gene regulatory Mediator submodule. (2008) (49)
- A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning. (2020) (45)
- Phase Separation, Protein Disorder, and Enhancer Function (2018) (43)
- An Integrated Chemical Cross-linking and Mass Spectrometry Approach to Study Protein Complex Architecture and Function* (2011) (42)
- In vivo regulation of the Escherichia coli araC promoter (1983) (37)
- TFIIH generates a six base-pair open complex during RNAP II transcription initiation and start-site scanning (2017) (33)
- TFIIIC determines RNA polymerase III specificity at the TATA-containing yeast U6 promoter. (1995) (30)
- TFIIB-related factors in RNA polymerase I transcription. (2013) (29)
- Mutations on the DNA Binding Surface of TBP Discriminate between Yeast TATA and TATA-Less Gene Transcription (2014) (27)
- Mechanistic Differences in Transcription Initiation at TATA-Less and TATA-Containing Promoters (2017) (27)
- Activation and the role of reinitiation in the control of transcription by RNA polymerase II. (1998) (24)
- Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II* (2016) (24)
- Architecture of the S. cerevisiae RNA polymerase I Core Factor complex (2014) (22)
- Efficiency in activation (1993) (18)
- Mediator subunit Med15 dictates the conserved “fuzzy” binding mechanism of yeast transcription activators Gal4 and Gcn4 (2019) (18)
- Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator (2017) (16)
- Visualization of novel virulence activities of the Xanthomonas type III effectors AvrBs1, AvrBs3 and AvrBs4. (2009) (14)
- SAGA Is a General Cofactor for RNA Polymerase II Transcription. (2018) (14)
- Domains of Tra 1 Important for Activator Recruitment and Transcription Coactivator Functions of SAGA and NuA 4 Complexes † (2011) (12)
- Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH (2016) (12)
- Recognition of AvrBs 3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs 3 Alleles 1 [ W ] (2009) (11)
- BET family members Bdf1/2 modulate global transcription initiation and elongation in Saccharomyces cerevisiae (2021) (6)
- A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning. (2020) (5)
- Clamping the TBP stirrup (1995) (5)
- Boch Effectors Breaking the Code of DNA Binding Specificity of TAL-Type III (2011) (5)
- An improved ChEC-seq method accurately maps the genome-wide binding of transcription coactivators and sequence-specific transcription factors (2021) (4)
- The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning. (2021) (4)
- Structural biology: New beginnings for transcription (2009) (4)
- Structural biology: Snapshots of transcription initiation (2016) (3)
- Ellis Englesberg and the Discovery of Positive Control in Gene Regulation (2014) (3)
- Transcription. Efficiency in activation. (1993) (2)
- Transcription activator-coactivator specificity is mediated by a large and dynamic fuzzy protein-protein complex (2017) (2)
- Yeast Mediator facilitates transcription initiation at most promoters via a Tail-independent mechanism. (2022) (2)
- An improved ChEC-seq method for mapping the genome-wide binding of S. cerevisiae transcription factors v3 (2020) (1)
- The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning (2020) (1)
- A high-throughput screen for transcription activation domains reveals their sequence characteristics and permits reliable prediction by deep learning (2019) (1)
- An improved ChEC-seq method for mapping the genome-wide binding of S. cerevisiae transcription factors v2 (2020) (1)
- An improved ChEC-seq method for mapping the genome-wide binding of S. cerevisiae transcription factors v1 (2020) (0)
- Mediator is broadly recruited to gene promoters via a Tail-independent mechanism (2021) (0)
- Structure of the complex of the central activation doamin of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 (2012) (0)
- Architecture of the S . cerevisiae SAGA transcription coactivator complex (2014) (0)
- Broad compatibility between yeast UAS elements and core promoters and identification of promoter elements that determine cofactor specificity (2022) (0)
- Structural analysis of the TBP/TFIIA/TATA complex (1996) (0)
- Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18 (2008) (0)
- Mechanisms of Eukaryotic Transcription Initiation (2012) (0)
- Genetic Dissection of the Interaction Between the Plant Pathogen Xanthomonas campestris pv. vesicatoria and Its Host Plants (2008) (0)
- PNAS Plus Significance Statements (2015) (0)
- Running head : Recognition of AvrBs 3-like proteins Corresponding (2009) (0)
- Supplementary material Text (2009) (0)
- Complex Structure of the Activation Domain of Gcn4 bound to the Mediator Co-Activator Domain of Gal11/Med15 (2010) (0)
- submodule system correlation identifies a gene regulatory Mediator − Structure Material Supplemental (2008) (0)
- Isolation of the gene encoding the yeast TATA binding TFIID: a gene identical to the SPT15 suppressor of Ty element insertions (1989) (0)
- Structure(?) and Function of Acidic Transcription Activators Minireview (1993) (0)
- methylof amino acid biosynthesis, sulfometuron Global expression profiling of yeast treated with an (2015) (0)
- Mechanism and regulation of RNA Polymerase II transcription (2010) (0)
- Tfiih Generates a Six-Base-Pair Open Complex during Eukaryotic Transcription Initiation (2019) (0)
- Solution structure of yeast Med15 ABD2 residues 277-368 (2018) (0)
- Two separate roles for the transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA (2019) (0)
- Transcription. Clamping the TBP stirrup. (1995) (0)
- SAGA Is a General Cofacto r for RNA Polymerase II Transcription Graphical Abstract Highlights (2017) (0)
- Author response: Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA (2019) (0)
- Human TFIID bound to promoter DNA and TFIIA (2018) (0)
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