Steven Lanier Mcknight
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Steven Lanier Mcknightbiology Degrees
Biology
#6622
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#9379
Historical Rank
Molecular Biology
#698
World Rank
#715
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Biochemistry
#863
World Rank
#970
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Biology
Steven Lanier Mcknight's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of North Carolina at Chapel Hill
Why Is Steven Lanier Mcknight Influential?
(Suggest an Edit or Addition)Steven Lanier Mcknight's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. (1988) (3112)
- A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF (2001) (2462)
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels (2012) (1615)
- Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. (1991) (1611)
- Eukaryotic transcriptional regulatory proteins. (1989) (1035)
- Transcriptional control signals of a eukaryotic protein-coding gene. (1982) (1013)
- Regulation of Clock and NPAS2 DNA Binding by the Redox State of NAD Cofactors (2001) (979)
- Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. (1995) (974)
- An interleukin-4-induced transcription factor: IL-4 Stat. (1994) (887)
- Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes (2005) (863)
- Scissors-grip model for DNA recognition by a family of leucine zipper proteins. (1989) (854)
- Isolation of a recombinant copy of the gene encoding C/EBP. (1988) (841)
- Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. (1988) (783)
- CCAAT-enhancer binding protein: a component of a differentiation switch. (1991) (707)
- Influence of Metabolism on Epigenetics and Disease (2013) (705)
- Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies (2012) (681)
- The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. (1998) (666)
- The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. (1989) (567)
- NPAS2: An Analog of Clock Operative in the Mammalian Forebrain (2001) (559)
- Transcriptional selectivity of viral genes in mammalian cells (1986) (556)
- Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. (1989) (529)
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells (2014) (509)
- Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. (1987) (498)
- Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains (2017) (470)
- Acetate Dependence of Tumors (2014) (464)
- Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region (1981) (444)
- The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. (1980) (438)
- In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage. (1988) (421)
- CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. (1989) (411)
- NPAS2: A Gas-Responsive Transcription Factor (2002) (410)
- Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complex. (1991) (406)
- Altered Patterns of Sleep and Behavioral Adaptability in NPAS2-Deficient Mice (2003) (403)
- Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene (1986) (397)
- Metabolism and the control of circadian rhythms. (2002) (392)
- Ultrastructural patterns of RNA synthesis during early embryogenesis of Drosophila melanogaster (1976) (379)
- Identification of Ets- and notch-related subunits in GA binding protein. (1991) (332)
- Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism (2009) (320)
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains (2013) (309)
- Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers (2016) (304)
- Discovery of a Proneurogenic, Neuroprotective Chemical (2010) (297)
- The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA (1998) (293)
- Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16. (1988) (278)
- Components of a Stat recognition code: evidence for two layers of molecular selectivity. (1995) (273)
- Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. (1992) (259)
- Is CCAAT/enhancer-binding protein a central regulator of energy metabolism? (1989) (244)
- Cyclic changes in metabolic state during the life of a yeast cell (2007) (241)
- Impaired cued and contextual memory in NPAS2-deficient mice. (2000) (236)
- Restriction of DNA Replication to the Reductive Phase of the Metabolic Cycle Protects Genome Integrity (2007) (236)
- The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets, and Nuclei (2015) (232)
- Metabolic cycles as an underlying basis of biological oscillations (2006) (222)
- Identification and purification of human Stat proteins activated in response to interleukin-2. (1995) (218)
- Cognate DNA binding specificity retained after leucine zipper exchange between GCN4 and C/EBP. (1989) (206)
- Electron microscopic analysis of chromatin replication in the cellular blastoderm drosophila melanogaster embryo (1977) (206)
- Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system. (1997) (193)
- P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage (2014) (181)
- The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence (1984) (181)
- Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export (2017) (179)
- McBindall—A Better Name for CCAAT/Enhancer Binding Proteins? (2001) (171)
- Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors. (2004) (169)
- NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions. (2006) (166)
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains (2014) (164)
- Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene. (1990) (156)
- Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus (1982) (154)
- Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus (1988) (153)
- The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice. (2005) (150)
- Oxygen Sensing Gets a Second Wind (2002) (147)
- Development of proneurogenic, neuroprotective small molecules. (2011) (145)
- A genetic approach to promoter recognition during trans induction of viral gene expression. (1986) (143)
- Electron microscopic analysis of chromosome metabolism in the Drosophila melanogaster embryo. (1978) (130)
- Phosphorylation of CCAAT-enhancer binding protein by protein kinase C attenuates site-selective DNA binding. (1992) (122)
- Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro. (1980) (120)
- Transcriptional and post-transcriptional controls establish the cascade of herpes simplex virus protein synthesis. (1987) (117)
- Coordinate Regulation of Sugar Flux and Translation by PAS Kinase (2002) (116)
- Evidence of changes in protease sensitivity and subunit exchange rate on DNA binding by C/EBP. (1990) (111)
- PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase (2001) (111)
- Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis (2012) (108)
- Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease (2012) (107)
- Post-replicative nonribosomal transcription units in D. melanogaster embryos (1979) (104)
- A Solid-State Conceptualization of Information Transfer from Gene to Message to Protein. (2018) (101)
- Purification of a set of cellular polypeptides that bind to the purine-rich cis-regulatory element of herpes simplex virus immediate early genes. (1989) (100)
- Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes (1985) (99)
- Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain (2019) (98)
- P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury. (2014) (94)
- Molecular zippers in gene regulation. (1991) (94)
- Ribonucleoprotein structure in nascent hnRNA is nonrandom and sequence-dependent (1980) (87)
- Discovery of antivirals against smallpox. (2004) (87)
- Molecular and genetic characterization of GABP beta. (1994) (82)
- The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA. (1998) (81)
- Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat (1985) (80)
- Building better vasculature. (2001) (77)
- tk Enzyme expression in differentiating muscle cells is regulated through an internal segment of the cellular tk gene (1984) (76)
- A Conserved DNA Damage Response Pathway Responsible for Coupling the Cell Division Cycle to the Circadian and Metabolic Cycles (2007) (74)
- Anatomy of an enhancer (1992) (73)
- On Getting There from Here (2010) (62)
- ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism (2018) (61)
- P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. (2014) (60)
- Targeted killing of a mammalian cell based upon its specialized metabolic state (2011) (52)
- Transcription revisited: a commentary on the 1995 Cold Spring Harbor Laboratory meeting, "Mechanisms of Eukaryotic Transcription". (1996) (52)
- Cross-β Polymerization of Low Complexity Sequence Domains. (2017) (50)
- Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity (2007) (49)
- Visualization of the silk fibroin transcription unit and nascent silk fibroin molecules on polyribosomes of Bombyx mori. (1976) (48)
- Structural characterization of the D290V mutation site in hnRNPA2 low-complexity–domain polymers (2018) (41)
- Genetic and physical analysis of the chicken tk gene (1984) (38)
- Metabolic Specialization of Mouse Embryonic Stem Cells (2012) (34)
- Gene Switching by Metabolic Enzymes—How Did You Get on the Invitation List? (2003) (33)
- Accurate transcription of cloned Xenopus rRNA genes by RNA polymerase I: demonstration by S1 nuclease mapping. (1982) (32)
- Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain (2020) (30)
- The yeast metabolic cycle: insights into the life of a eukaryotic cell. (2007) (27)
- Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat (1985) (23)
- Let the data speak (2006) (20)
- Immunological cross-reaction between calf and Drosophila histones. (1977) (19)
- Cross-β polymerization and hydrogel formation by low-complexity sequence proteins. (2017) (18)
- Transiently structured head domains control intermediate filament assembly (2020) (18)
- Evidence of carbon monoxide-mediated phase advancement of the yeast metabolic cycle (2009) (18)
- Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries. (2005) (17)
- 29 CCAAT/Enhancer Binding Protein (1992) (16)
- Constitutive transcriptional control signals of the herpes simplex virus tk gene. (1983) (16)
- Ultrastructural analysis of ribosomal gene transcription in vitro. (1980) (16)
- Glimpses of allostery in the control of eukaryotic gene expression. (1993) (15)
- Mutations linked to neurological disease enhance self-association of low-complexity protein sequences (2022) (13)
- Differentiation of T‐helper lymphocytes: selective regulation by members of the STAT family of transcription factors (1996) (13)
- Dynamic structural order of a low-complexity domain facilitates assembly of intermediate filaments (2020) (12)
- Benefits of Enhancing Nicotinamide Adenine Dinucleotide Levels in Damaged or Diseased Nerve Cells. (2019) (12)
- How do protein domains of low sequence complexity work? (2021) (12)
- Chapter IV – Transcriptional Units in Eukaryotic Chromosomes (1979) (8)
- The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores (2021) (8)
- Please keep me 2uned to PKM2. (2014) (7)
- Redox-mediated regulation of low complexity domain self-association. (2021) (7)
- WAT-free mice: diabetes without obesity. (1998) (6)
- Erratum: Phosphorylation-regulated binding of RNA polymerase ii to fibrous polymers of low-complexity domains (Cell (2013) 155 (1049-1060)) (2014) (6)
- Molecular and genetic characterization of GABPI3 (1994) (6)
- Identification, cloning and sequencing of the HSV thymidine kinase genes (1981) (6)
- Gatekeepers of organ growth. (1997) (5)
- Back to the future: molecular biology meets metabolism. (2011) (4)
- Prediction of a dimerization surface common to a new class of sequence-specific DNA binding proteins. (1988) (3)
- Passing Through. (2019) (2)
- Phage a: a genetic switch. (1986) (2)
- A hypothetical means of treating or preventing cancer (2014) (2)
- Discovery of a transcription factor that catalyzes terminal cell differentiation. (1991) (2)
- Two Distinct High Throughput Screens of PAS Kinase Yield Convergent Insight to Enzyme Function (2006) (2)
- Studies on the Regulation of Thymidine Kinase Enzyme Expression (1984) (2)
- Oscar Miller (1925–2012) (2012) (1)
- P 7 C 3 Q 1 Q 2 and an unbiased approach to drug discovery for neurodegenerative diseases (2014) (1)
- Concerted effort: oscillations in global gene expression during nematode development. (2014) (1)
- Molecular structure of FUS low sequence complexity domain protein fibrils (2017) (1)
- Redox-mediated regulation of a labile, evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain (2019) (0)
- Tissue-Specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/ennancer binding protein (2007) (0)
- New Ideas About Cell Organization via Cross-β Polymerization of Low-Complexity Protein Sequences (2016) (0)
- Differentiation and gene regulation. (1995) (0)
- Gene expression and differentiation Editorial overview (1993) (0)
- gene.and physical analysis of the chicken tk (2013) (0)
- Biological and medical relevance of circadian and metabolic cycles (2009) (0)
- Differentiation and gene regulation The devil is in the detail (1998) (0)
- Supporting Online Material for DNA Replication Restricted to the Reductive Phase of the Metabolic Cycle Protects Genome Integrity (2007) (0)
- 2D and 3D solid state NMR spectra of FUS-LC fibrils (2017) (0)
- Functional Anatomy of the TDP-43 Redox Sensor (2021) (0)
- Commentary Gatekeepers of organ growth (1997) (0)
- Catabolism Dependence of Mouse Embryonic Stem Cells on Threonine (2012) (0)
- A hypothetical means of treating or preventing cancer (2014) (0)
- Phage λ: A Genetic Switch . Gene Control and Phage λ. Marc Ptashne. Cell Press and Blackwell Scientific, Palo Alto, CA, 1986. x, 128 pp., illus. Paper, $16.95. (1986) (0)
- Abstract IA-18: Mouse embryonic stem cells exist in a unique metabolic state (2009) (0)
- IDENTIFICATION OF A TRANSCRIPTIONAL CONTROL REGION UPSTREAM FROM THE HSV THYMIDINE KINASE GENE (1981) (0)
- Pure Genes, Pure Genius (2012) (0)
- United States Patent 19 McKnight et al . 54 INTERLEUKIN 4 SIGNAL TRANSDUCERS 75 Inventors : (2017) (0)
- Molecular and genetic characterization of GABPI 3 (2007) (0)
- Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. (2014) (0)
- Tracing the genetics of neurological disease to the mutation-directed addition of single hydrogen bonds (2021) (0)
- Signal transduction by PAS-domain containing heme-based sensors: an overview (2003) (0)
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