Steven Mark Albelda
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Steven Mark Albelda's Degrees
- Doctorate Medicine University of Pennsylvania
- PhD Immunology University of Pennsylvania
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(Suggest an Edit or Addition)Steven Mark Albelda's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. (2009) (2381)
- Integrins and other cell adhesion molecules (1990) (1971)
- BRAF and RAS mutations in human lung cancer and melanoma. (2002) (1106)
- Adhesion molecules and inflammatory injury (1994) (1055)
- Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity (2005) (997)
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains (2009) (772)
- Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression. (1990) (768)
- Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule (1991) (684)
- Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies (2013) (665)
- Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. (1992) (664)
- Role of integrins and other cell adhesion molecules in tumor progression and metastasis. (1993) (643)
- Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength (1993) (614)
- Tumor-associated neutrophils: friend or foe? (2012) (571)
- Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response1 (2007) (563)
- CAR T Cell Therapy for Solid Tumors. (2017) (542)
- The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. (1998) (526)
- Involvement of endothelial PECAM-1/CD31 in angiogenesis. (1997) (525)
- Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. (1993) (507)
- Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients (2016) (489)
- The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. (2011) (480)
- Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T cells Expressing a Mesothelin-Specific Chimeric Antibody Receptor (2011) (421)
- Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. (2014) (417)
- EndoCAM: a novel endothelial cell-cell adhesion molecule (1990) (404)
- CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion (1992) (392)
- Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor. (2010) (389)
- T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans (2013) (371)
- Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity (2013) (350)
- Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. (1998) (347)
- Endothelial and epithelial cell adhesion molecules. (1991) (347)
- Molecular and functional aspects of PECAM-1/CD31. (1994) (332)
- Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells. (2015) (326)
- Tuberculous pleural effusions. (1987) (324)
- Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors (2014) (322)
- Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. (1994) (306)
- A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1 (2003) (304)
- Prognostic Implications of Cell Cycle, Apoptosis, and Angiogenesis Biomarkers in Non–Small Cell Lung Cancer: A Review (2005) (293)
- Targeting Cardiac Fibrosis with Engineered T cells (2019) (287)
- Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. (1996) (286)
- Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils (2012) (269)
- Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer. (2016) (263)
- T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis (1994) (249)
- Metabolic imaging of malignant pleural mesothelioma with fluorodeoxyglucose positron emission tomography. (1998) (249)
- Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo. (1993) (232)
- Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. (1993) (218)
- Chimeric antigen receptor T-cell therapy for solid tumors (2016) (209)
- An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane (1996) (208)
- Epigenomic‐Guided Mass Cytometry Profiling Reveals Disease‐Specific Features of Exhausted CD8 T Cells (2018) (196)
- Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. (1998) (196)
- Individually Distinct Ig Homology Domains in PECAM-1 Regulate Homophilic Binding and Modulate Receptor Affinity (*) (1996) (189)
- CAR T cells produced in vivo to treat cardiac injury (2022) (188)
- Permeability characteristics of cultured endothelial cell monolayers. (1988) (188)
- Distribution of integrin cell adhesion receptors in normal and malignant lung tissue. (1992) (178)
- Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. (1993) (177)
- Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. (1994) (173)
- Neutrophils recruit regulatory T‐cells into tumors via secretion of CCL17—A new mechanism of impaired antitumor immunity (2014) (172)
- Identification and characterization of cell-substratum adhesion receptors on cultured human endothelial cells. (1989) (167)
- CCL2 blockade augments cancer immunotherapy. (2010) (164)
- Inhibition of p300 impairs Foxp3+ T-regulatory cell function and promotes anti-tumor immunity (2012) (160)
- Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non-small cell lung cancer from patients with nonmalignant lung disease. (2009) (158)
- A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31) (1992) (157)
- Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers. (2019) (154)
- Diagnostic utility of pleural fluid eosinophilia. (1984) (154)
- Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery (2012) (151)
- Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) Homophilic Adhesion Is Mediated by Immunoglobulin-like Domains 1 and 2 and Depends on the Cytoplasmic Domain and the Level of Surface Expression* (1996) (145)
- A Phase I Clinical Trial of Single-Dose Intrapleural IFN-β Gene Transfer for Malignant Pleural Mesothelioma and Metastatic Pleural Effusions: High Rate of Antitumor Immune Responses (2007) (145)
- Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization (2016) (144)
- Tumor-associated neutrophils display a distinct N1 profile following TGFβ modulation: A transcriptomics analysis of pro- vs. antitumor TANs (2016) (144)
- Murine platelet endothelial cell adhesion molecule (PECAM‐1)/CD31 modulates β2 integrins on lymphokine‐activated killer cells (1993) (142)
- Advances in the treatment of malignant pleural mesothelioma. (1999) (142)
- Prognostic value of FDG PET imaging in malignant pleural mesothelioma. (1999) (140)
- Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs. (1999) (139)
- Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury (2003) (139)
- Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer (2019) (136)
- Role of fiberoptic bronchoscopy in the diagnosis of invasive pulmonary aspergillosis in patients with acute leukemia. (1984) (135)
- Gene expression profiling of malignant mesothelioma. (2003) (133)
- Platelet endothelial cell adhesion molecule, PECAM‐1, modulates cell migration (1992) (131)
- Mesothelin, a novel immunotherapy target for triple negative breast cancer (2012) (130)
- Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. (1994) (130)
- PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. (2003) (128)
- Pulmonary cavitation and massive hemoptysis in invasive pulmonary aspergillosis. Influence of bone marrow recovery in patients with acute leukemia. (2015) (125)
- Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. (1993) (125)
- Use of carrier cells to deliver a replication-selective herpes simplex virus-1 mutant for the intraperitoneal therapy of epithelial ovarian cancer. (1999) (125)
- Biosynthesis and processing of the cell adhesion molecule PECAM-1 includes production of a soluble form. (1994) (123)
- Long-term Follow-up of Patients with Malignant Pleural Mesothelioma Receiving High-Dose Adenovirus Herpes Simplex Thymidine Kinase/Ganciclovir Suicide Gene Therapy (2005) (123)
- Progression-related expression of beta3 integrin in melanomas and nevi. (1999) (122)
- Monocyte chemoattractant protein-1 blockade inhibits lung cancer tumor growth by altering macrophage phenotype and activating CD8+ cells. (2011) (122)
- Intraoperative near-infrared imaging can identify pulmonary nodules. (2014) (122)
- ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. (2011) (122)
- Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms. (2010) (121)
- Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype. (1999) (121)
- Diffuse pulmonary hemorrhage: a review and classification. (1985) (120)
- Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats. (1996) (119)
- Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment1 (2000) (117)
- Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma. (2005) (117)
- Activation of cAMP-dependent pathways in human airway smooth muscle cells inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression and T lymphocyte adhesion. (1995) (116)
- ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface. (2003) (115)
- Invasive pulmonary aspergillosis and acute leukemia. Limitations in the diagnostic utility of the air crescent sign. (1985) (115)
- Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity. (2001) (114)
- Use of a "replication-restricted" herpes virus to treat experimental human malignant mesothelioma. (1997) (113)
- The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer (2009) (112)
- Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma (2005) (112)
- Identification of integrin receptors on cultured human bone cells (1994) (112)
- Urinary Volatile Compounds as Biomarkers for Lung Cancer: A Proof of Principle Study Using Odor Signatures in Mouse Models of Lung Cancer (2010) (112)
- Regulation of Mouse PECAM-1 Tyrosine Phosphorylation by the Src and Csk Families of Protein-tyrosine Kinases* (1998) (111)
- Distribution of integrin cell adhesion receptors on normal bronchial epithelial cells and lung cancer cells in vitro and in vivo. (1993) (111)
- Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma. (2009) (110)
- Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies. (2008) (109)
- Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases. (2013) (109)
- Integrin Distribution in Malignant Melanoma : Association of the ß 3 Subunit with Tumor Progression 1 (2006) (108)
- The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis (2012) (108)
- Size-dependent intracellular immunotargeting of therapeutic cargoes into endothelial cells. (2002) (107)
- Advances in the diagnosis, evaluation, and management of malignant pleural mesothelioma (2005) (107)
- A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions. (2010) (106)
- Adhesion molecules in the lung. An overview. (1993) (106)
- Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties (1994) (104)
- Novel therapies for malignant pleural mesothelioma. (2018) (104)
- Human/severe combined immunodeficient mouse chimeras. An experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules. (1993) (103)
- Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events (1990) (103)
- A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection (2007) (102)
- CD40-mediated signal transduction in human airway smooth muscle. (1998) (100)
- T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. (2013) (100)
- Gene therapy approaches for inherited and acquired lung diseases. (1996) (99)
- Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo. (1997) (98)
- Blockade of Programmed Death 1 Augments the Ability of Human T Cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer (2015) (97)
- Platelet endothelial cell adhesion molecule (CD31). (1993) (96)
- Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma* (2008) (95)
- Gene therapy using adenovirus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer. (1995) (95)
- Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap. (2017) (95)
- Intraoperative Near-Infrared Imaging Can Distinguish Cancer from Normal Tissue but Not Inflammation (2014) (94)
- Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release. (1998) (92)
- PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress. (2003) (92)
- Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines (2018) (91)
- Cycloxygenase-2 Inhibition Augments the Efficacy of a Cancer Vaccine (2006) (90)
- Alternative Splicing of a Specific Cytoplasmic Exon Alters the Binding Characteristics of Murine Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) (*) (1995) (90)
- Urinary Volatile Compounds as Biomarkers for Lung Cancer (2012) (89)
- Use of cyclooxygenase-2 inhibition to enhance the efficacy of immunotherapy. (2003) (89)
- A trial of intrapleural adenoviral-mediated Interferon-α2b gene transfer for malignant pleural mesothelioma. (2011) (88)
- Gene expression profiling of the early pulmonary response to hyperoxia in mice. (2003) (88)
- Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC. (2019) (88)
- Severe hemoptysis associated with pulmonary aspergilloma. Percutaneous intracavitary treatment. (1988) (87)
- A phase I trial of repeated intrapleural adenoviral-mediated interferon-beta gene transfer for mesothelioma and metastatic pleural effusions. (2010) (86)
- Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy. (2008) (86)
- Transforming Growth Factor-β Receptor Blockade Augments the Effectiveness of Adoptive T-Cell Therapy of Established Solid Cancers (2008) (84)
- Alterations in Cell Cycle Genes in Early Stage Lung Adenocarcinoma Identified by Expression Profiling (2003) (84)
- Nontuberculous mycobacterial infection in AIDS: clinical, pathologic, and radiographic features. (1986) (81)
- 4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling (2020) (81)
- Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. (2000) (80)
- Gene Therapy for Lung Disease: Hype or Hope? (2000) (79)
- Differential expression of the cell adhesion molecules ICAM-1, VCAM-1, and E-selectin in normal and posttransplantation myocardium. Cell adhesion molecule expression in human cardiac allografts. (1994) (78)
- Association of murine CD31 with transmigrating lymphocytes following antigenic stimulation. (1992) (77)
- Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors (2015) (75)
- Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects (2007) (75)
- An NK-like CAR T cell transition in CAR T cell dysfunction (2021) (73)
- Localization of multiple functional domains on human PECAM-1 (CD31) by monoclonal antibody epitope mapping. (1995) (72)
- Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3 + T-regulatory Cell Function and Promotes Antitumor Immunity (2016) (72)
- IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells (2013) (72)
- Measurement of individual cell migration parameters for human tissue cells (1992) (71)
- Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy. (2010) (71)
- Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature. (2005) (71)
- Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes. (2008) (71)
- PECAM-1-dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization. (2003) (70)
- Targeted Detoxification of Selected Reactive Oxygen Species in the Vascular Endothelium (2009) (70)
- Immunological effects of the TGFβ-blocking antibody GC1008 in malignant pleural mesothelioma patients (2013) (70)
- Soluble Type II Transforming Growth Factor-β Receptor Inhibits Established Murine Malignant Mesothelioma Tumor Growth by Augmenting Host Antitumor Immunity (2004) (69)
- Identification of integrin cell‐substratum adhesion receptors on cultured rat bone cells (1992) (69)
- Junctional adhesion molecule-C (JAM-C) regulates polarized neutrophil transendothelial cell migration in vivo (2011) (68)
- Replication-selective herpes simplex virus type 1 mutant therapy of cervical cancer is enhanced by low-dose radiation. (2002) (68)
- B-cell Depletion Using an Anti-CD20 Antibody Augments Antitumor Immune Responses and Immunotherapy in Nonhematopoetic Murine Tumor Models (2008) (68)
- Gene signatures of tumor inflammation and epithelial-to-mesenchymal transition (EMT) predict responses to immune checkpoint blockade in lung cancer with high accuracy. (2020) (67)
- Multi-attenuated herpes simplex virus-1 mutant G207 exerts cytotoxicity against epithelial ovarian cancer but not normal mesothelium and is suitable for intraperitoneal oncolytic therapy (2000) (66)
- Expanding spectrum of pulmonary disease caused by nontuberculous mycobacteria. (1985) (66)
- Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature. (2002) (65)
- Prevention of Alveolar Destruction and Airspace Enlargement in a Mouse Model of Pulmonary Lymphangioleiomyomatosis (LAM) (2012) (63)
- Pilot and Feasibility Trial Evaluating Immuno-Gene Therapy of Malignant Mesothelioma Using Intrapleural Delivery of Adenovirus-IFNα Combined with Chemotherapy (2016) (63)
- The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas. (2015) (62)
- Oncolytic herpes simplex virus-1 lacking ICP34.5 induces p53-independent death and is efficacious against chemotherapy-resistant ovarian cancer. (2000) (62)
- Using macrophage activation to augment immunotherapy of established tumours (2013) (61)
- Distribution of integrin cell adhesion molecules in endometrial cancer. (1995) (61)
- Lower serum endocan levels are associated with the development of acute lung injury after major trauma. (2009) (61)
- A 10-Gene Classifier for Distinguishing Head and Neck Squamous Cell Carcinoma and Lung Squamous Cell Carcinoma (2007) (60)
- Expression and function of endothelial cell alpha v integrin receptors in wound-induced human angiogenesis in human skin/SCID mice chimeras. (1997) (60)
- Kinetics of soluble mesothelin in patients with malignant pleural mesothelioma during treatment. (2009) (59)
- Cell‐selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting (2001) (59)
- Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the herpes simplex virus thymidine kinase gene. (1996) (58)
- Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing (2003) (58)
- Vascular immunotargeting of glucose oxidase to the endothelial antigens induces distinct forms of oxidant acute lung injury: targeting to thrombomodulin, but not to PECAM-1, causes pulmonary thrombosis and neutrophil transmigration. (2002) (56)
- Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non–Small Cell Lung Cancer (2019) (56)
- Changes in Plasma Gelsolin Concentration During Acute Oxidant Lung Injury in Mice (2002) (56)
- Novel Cytokine-independent Induction of Endothelial Adhesion Molecules Regulated by Platelet/Endothelial Cell Adhesion Molecule (CD31) (1997) (56)
- Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1/CD31): A Multifunctional Vascular Cell Adhesion Molecule. (1997) (55)
- Ligation of Endothelial αvβ3 Integrin Increases Capillary Hydraulic Conductivity of Rat Lung (1995) (55)
- Immuno-gene therapy with interferon-beta before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma. (2004) (55)
- Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation. (2009) (55)
- Platelet-Endothelial Cell Adhesion Molecule-1-Directed Endothelial Targeting of Superoxide Dismutase Alleviates Oxidative Stress Caused by Either Extracellular or Intracellular Superoxide (2007) (53)
- An optimized disaggregation method for human lung tumors that preserves the phenotype and function of the immune cells (2015) (53)
- Tyrosine Residue in Exon 14 of the Cytoplasmic Domain of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) Regulates Ligand Binding Specificity (1997) (53)
- A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection. (2007) (52)
- Characterization of beta-adrenergic receptors in cultured human and bovine endothelial cells. (1988) (52)
- Expression of platelet‐endothelial cell adhesion molecule‐1 (PECAM‐1) during melanoma‐induced angiogenesis in vivo (1993) (52)
- Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors. (2013) (51)
- Distinct Effects of IL-18 on the Engraftment and Function of Human Effector CD8+ T Cells and Regulatory T Cells (2008) (51)
- Cytoplasmic and transmembrane domains of integrin beta 1 and beta 3 subunits are functionally interchangeable (1991) (51)
- Advanced glycation end products on stored red blood cells increase endothelial reactive oxygen species generation through interaction with receptor for advanced glycation end products (2010) (51)
- Gene therapy for malignant pleural mesothelioma. (1998) (50)
- Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer. (1999) (50)
- Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature. (2008) (50)
- PECAM-1 (CD31) regulates a hydrogen peroxide–activated nonselective cation channel in endothelial cells (2002) (50)
- Resection of Non–Small Cell Lung Cancers Reverses Tumor-Induced Gene Expression Changes in the Peripheral Immune System (2011) (49)
- Cytokine-induced expression of transforming growth factor-alpha and the epidermal growth factor receptor in neonatal skin explants. (1992) (48)
- Cell adhesion molecules in asthma: homing, activation, and airway remodeling. (1995) (48)
- Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung. (2005) (47)
- Analysis of the immunologic response generated by Ad.IFN-beta during successful intraperitoneal tumor gene therapy. (2002) (46)
- Leukocyte recruitment into human skin transplanted onto severe combined immunodeficient mice induced by TNF-alpha is dependent on E-selectin. (1994) (46)
- A pilot study of systemic corticosteroid administration in conjunction with intrapleural adenoviral vector administration in patients with malignant pleural mesothelioma (2000) (46)
- Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness (2012) (46)
- Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia. (2006) (45)
- RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. (2008) (45)
- Adsorption and elution of extracellular matrix proteins on non-tissue culture polystyrene petri dishes (1992) (44)
- Cellular and molecular aspects of PECAM-1. (1992) (44)
- Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors. (2017) (44)
- Immunotargeting of glucose oxidase to endothelium in vivo causes oxidative vascular injury in the lungs. (2000) (44)
- MicroArray Data Simulator For Improved Selection of Differentially Expressed Genes (2003) (43)
- Modulation of endothelial targeting by size of antibody-antioxidant enzyme conjugates. (2011) (43)
- Detection of SV40 DNA sequences in malignant mesothelioma specimens from the United States, but not from Turkey (2002) (42)
- Ventilator-induced subpleural air cysts: clinical, radiographic, and pathologic significance. (2015) (42)
- Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice (2015) (40)
- Mesothelin-targeted CAR-T cell therapy for solid tumors (2020) (40)
- The vascular disrupting agent, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumor cytotoxic T lymphocytes. (2007) (40)
- Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms (2018) (40)
- Circulating tumor cells as a predictive biomarker in patients with small cell lung cancer undergoing chemotherapy. (2017) (39)
- Gene therapy for mesothelioma and lung cancer. (2010) (39)
- Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy. (2010) (38)
- Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer (2016) (37)
- Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates. (1996) (37)
- Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor. (2011) (36)
- ICAM-1 expression on bronchial epithelium after recombinant adenovirus infection. (1995) (36)
- Pleural thickening: its significance and relationship to asbestos dust exposure. (2015) (36)
- Treating tumors with a vaccinia virus expressing IFNβ illustrates the complex relationships between oncolytic ability and immunogenicity. (2012) (35)
- Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo. (2020) (35)
- The Role of Immunosuppression in the Efficacy of Cancer Gene Therapy Using Adenovirus Transfer of the Herpes Simplex Thymidine Kinase Gene (1995) (35)
- Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) (2016) (35)
- Vesicular stomatitis virus-induced immune suppressor cells generate antagonism between intratumoral oncolytic virus and cyclophosphamide. (2011) (35)
- Integrin expression in non-small cell carcinoma of the lung (1995) (34)
- The evaluation of adenoviral p53-mediated bystander effect in gene therapy of cancer (1999) (34)
- Platelet-endothelial cell adhesion molecule-1 is expressed by a subpopulation of human trophoblasts: a possible mechanism for trophoblast-endothelial interaction during haemochorial placentation. (1998) (34)
- Eighth International Mesothelioma Interest Group (2007) (34)
- Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models (2011) (34)
- Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium. (2007) (33)
- Gene therapy for lung cancer and mesothelioma. (1997) (33)
- Platelet endothelial cell adhesion molecule-1 in neutrophil emigration during acute bacterial pneumonia in mice and rats. (2003) (32)
- Herpes simplex 1716--an ICP 34.5 mutant--is severely replication restricted in human skin xenografts in vivo. (1996) (32)
- Identification of human-selective analogues of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) (2013) (32)
- Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy. (1999) (32)
- The effect of promoter strength in adenoviral vectors containing herpes simplex virus thymidine kinase on cancer gene therapy in vitro and in vivo. (1997) (31)
- Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis (2011) (31)
- Thymidylate Synthase and Folyl-Polyglutamate Synthase Are Not Clinically Useful Markers of Response to Pemetrexed in Patients with Malignant Pleural Mesothelioma (2013) (31)
- Treatment of advanced mesothelioma with the recombinant adenovirus H5.010RSVTK: a phase 1 trial (BB-IND 6274). (1996) (31)
- Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcgamma receptor function. (2004) (31)
- Evaluation of high-frequency jet ventilation in patients with bronchopleural fistulas by quantitation of the airleak. (1985) (30)
- Gene signature of antigen processing and presentation machinery predicts response to checkpoint blockade in non-small cell lung cancer (NSCLC) and melanoma (2020) (29)
- Cell adhesion receptors and early mammalian heart development: an overview. (1993) (29)
- CD11b+Ly6G+ cells inhibit tumor growth by suppressing IL-17 production at early stages of tumorigenesis (2015) (29)
- Functional genomics and expression profiling: be there or be square. (2000) (29)
- Bronchopleural fistula complicating invasive pulmonary aspergillosis. (1982) (28)
- Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes (2019) (28)
- Induction of E-selectin-dependent leukocyte recruitment by mast cell degranulation in human skin grafts transplanted on SCID mice. (1996) (28)
- A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade (2021) (28)
- Role of lateral cell-cell border location and extracellular/transmembrane domains in PECAM/CD31 mechanosensation. (2004) (27)
- Treatment of Lung Cancer Using Clinically Relevant Oral Doses of the Cyclooxygenase-2 Inhibitor Rofecoxib: Potential Value as Adjuvant Therapy After Surgery (2005) (27)
- Promoting metastasis: neutrophils and T cells join forces (2015) (26)
- Targeted Endothelial Delivery of Nanosized Catalase Immunoconjugates Protects Lung Grafts Donated After Cardiac Death (2011) (26)
- Pleural-based mesothelioma in immune competent rats: a model to study adenoviral gene transfer. (1995) (26)
- Interferon β adenoviral gene therapy in a patient with ovarian cancer (2006) (26)
- Experimental production and modulation of human cytotoxic dermatitis in human-murine chimeras. (1997) (26)
- Differential sensitivity of thoracic malignant tumors to adenovirus-mediated drug sensitization gene therapy. (1995) (26)
- Ligation of endothelial alpha v beta 3 integrin increases capillary hydraulic conductivity of rat lung. (1995) (25)
- Peripheral Immune Cell Gene Expression Predicts Survival of Patients with Non-Small Cell Lung Cancer (2012) (25)
- CD 40-Mediated Signal Transduction in Human Airway Smooth Muscle 1 (1998) (25)
- PECAM‐1 (CD31) engagement activates a phosphoinositide‐independent, nonspecific cation channel in endothelial cells (2001) (25)
- Immunotargeting of glucose oxidase: intracellular production of H2O2and endothelial oxidative stress. (1999) (25)
- Vascular endothelial-targeted therapy combined with cytotoxic chemotherapy induces inflammatory intratumoral infiltrates and inhibits tumor relapses after surgery. (2012) (24)
- Expression of endothelial cell adhesion molecules in human bronchial xenografts. (1994) (22)
- Gene therapy for lung neoplasms. (2002) (22)
- Pharmacologic activation of the innate immune system to prevent respiratory viral infections. (2011) (22)
- Chimeric Antigen Receptor (CAR) T Cell Therapy for Malignant Pleural Mesothelioma (MPM) (2017) (22)
- Adenovirus-mediated gene transfer to human bronchial submucosal glands using xenografts. (1995) (22)
- Analysis and Augmentation of the Immunologic Bystander Effects of CAR T Cell Therapy in a Syngeneic Mouse Cancer Model (2020) (21)
- Gene therapy for lung neoplasms. (2002) (21)
- Differentially Expressed Apoptotic Genes in Early Stage Lung Adenocarcinoma Predicted by Expression Profiling (2003) (21)
- The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages (2017) (20)
- Endotoxin stimulates platelet-derived growth factor production from cultured human pulmonary endothelial cells. (1989) (19)
- Activation of mitogen-activated protein kinases by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) plays an important role in macrophage stimulation. (2011) (19)
- The receptor for advanced glycation end products mediates lung endothelial activation by RBCs. (2013) (19)
- Activation of the Nucleotide Oligomerization Domain Signaling Pathway by the Non-bacterially Derived Xanthone Drug 5′6-Dimethylxanthenone-4-acetic Acid (Vadimezan)* (2010) (18)
- Luminol Chemiluminescence Reports Photodynamic Therapy‐Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy (2018) (18)
- Use of circulating tumor cell technology (CELLSEARCH) for the diagnosis of malignant pleural effusions. (2012) (17)
- Effects of increased ventilation on lung lymph flow in unanesthetized sheep. (1986) (17)
- The function of cell adhesion molecules in lung inflammation: more questions than answers. (1998) (17)
- Immunohistochemical and molecular analysis of β1 and β3 integrins (1990) (17)
- Intracranial cycloheximide: Effect on male mouse sexual behavior and plasma testosterone (1976) (17)
- Immunotargeting of glucose oxidase: intracellular production of H(2)O(2) and endothelial oxidative stress. (1999) (16)
- Human skin/SCID mouse chimeras as an in vivo model for human cutaneous mast cell hyperplasia. (1997) (15)
- Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner (2018) (15)
- Recent advances in molecular biological techniques and their relevance to pulmonary research (2000) (14)
- Loss of cells expressing Fibroblast Activation Protein (FAP) has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis. (2019) (14)
- Blockade of TNF-α Decreases Both Inflammation and Efficacy of Intrapulmonary Ad.IFNβ Immunotherapy in an Orthotopic Model of Bronchogenic Lung Cancer (2006) (14)
- Differential expression of integrin cell-substratum adhesion receptors on endothelium. (1992) (14)
- Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure. (2015) (13)
- Variation in the MYLK gene is associated with development of acute lung injury after major trauma (2008) (13)
- Giving oncolytic vaccinia virus more BiTE. (2014) (13)
- The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System (2017) (13)
- Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion. (2018) (13)
- Cytokine gene therapy for malignant pleural mesothelioma. (2007) (13)
- Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma (2011) (12)
- Interferon beta adenoviral gene therapy in a patient with ovarian cancer. (2006) (12)
- The timing of TGF-β inhibition affects the generation of antigen-specific CD8+ T Cells (2013) (11)
- Valproic acid improves second-line regimen of small cell lung carcinoma in preclinical models (2015) (10)
- The in vivo and in vitro characterisation of an engineered human antibody to E-selectin. (1997) (10)
- Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells (2013) (9)
- Loss of αv Integrin Expression and Recurrence in Node-Negative Lung Carcinoma (1997) (9)
- A preclinical model to investigate the role of surgically‐induced inflammation in tumor responses to intraoperative photodynamic therapy (2018) (9)
- OA13.07 Intrapleural Modified Vaccine Strain Measles Virus Therapy for Patients with Malignant Pleural Mesothelioma (2017) (8)
- Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice. (2019) (8)
- Modifying tumor-associated macrophages (2013) (8)
- Treating Tumors With a Vaccinia Virus Expressing IFNβ Illustrates the Complex Relationships Between Oncolytic Ability and Immunogenicity. (2012) (8)
- TNFα Induces E-Selectin Expression and PECAM-1 (CD31) Redistribution in Extracutaneous Tissues (1993) (8)
- Culture of human adult endothelial cells on liquid-liquid interfaces: A new approach to the study of cell-matrix interactions (1991) (8)
- Loss of alpha-v integrin expression and recurrence in node-negative lung carcinoma. (1997) (7)
- Gene Therapy in Lung Disease (2002) (6)
- Inhibition of the ejaculatory reflex in B6D2F mice by testosterone propionate. (1976) (6)
- Molecular Characterization of Malignant Mesothelioma: Time for New Targets? (2018) (6)
- Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer. (2006) (6)
- Monitoring Therapeutic Response to Anti-Fibroblast Activation Protein (FAP) CAR T Cells using [18F]AlF-FAPI-74. (2022) (6)
- Current Advances in CAR T Cell Therapy for Malignant Mesothelioma (2020) (6)
- U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH RECOMBINANT DNA ADVISORY COMMITTEE Minutes of Meeting (2006) (6)
- Cytoplasmic and Transmembrane Domains ofIntegrin ßl and ß 3 Subunits Are Functionally Interchangeable (2002) (5)
- Molecular Imaging to Identify Tumor Recurrence following Chemoradiation in a Hostile Surgical Environment (2015) (5)
- Gene Therapy for Mesothelioma (2011) (5)
- Gene transfer and thoracic surgery: more to come. (1997) (5)
- Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging (2016) (5)
- Pulmonary extraction of propranolol in normal and oxygen-toxic sheep. (1989) (5)
- TNFerade to the rescue? Guidelines for evaluating phase I cancer gene transfer trials. (2004) (5)
- Immunohistochemical and molecular analysis of beta 1 and beta 3 integrins. (1990) (5)
- Measurement of Cell Adhesion and Migration on Protein-Coated Surfaces (1991) (5)
- Immunoconjugates of catalase attenuate radiation-induced pulmonary fibrosis in C57Bl mice (2001) (4)
- Pulmonary genetics, genomics, and gene therapy: conference summary. (2002) (4)
- The role of selectins and CD18 in leukotriene B4-mediated white blood cell emigration in human skin grafts transplanted on SCID mice. (1996) (4)
- Ventricular Tachycardia Terminated by Carotid Sinus Massage (1979) (4)
- 151 POSTER Efficacy of panobinostat (LBH589) in lung cancer: potent anticancer activity in both in vitro and in vivo tumor models (2008) (4)
- Microenvironment and Immunology Enhanced Effector Responses in Activated CD 8 þ T Cells De fi cient in Diacylglycerol Kinases (2013) (4)
- Recurrence after Surgical Resection and Prevents Tumor In vivo Mesothelioma Tumor Growth Type I Receptor Kinase ( SM 16 ) Inhibits Murine β Factor A Novel Small-Molecule Inhibitor of Transforming Growth (2007) (4)
- Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity (2020) (4)
- The role of cell adhesion molecules in asthma--an overview. (1993) (4)
- Surgical cytoreduction restores the antitumor efficacy of a Listeria monocytogenes vaccine in malignant pleural mesothelioma. (2015) (4)
- Phase I study of gene mediated cytotoxic immunotherapy (GMCI) for patients with malignant pleural effusion (MPE). (2016) (4)
- Molecular and Cellular Properties ofPECAM-1 ( endoCAM / CD 31 ) : A Novel Vascular Cell-Cell Adhesion Molecule (2002) (3)
- A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade (2021) (3)
- Abstract 539: A bispecific Fc-silenced IgG1 antibody (MCLA-145) requires PD-L1 binding to activate CD137 (2019) (3)
- Serum soluble mesothelin-related protein (SMRP) and fibulin-3 levels correlate with baseline malignant pleural mesothelioma (MPM) tumor volumes but are not useful as biomarkers of response in an immunotherapy trial. (2021) (3)
- Tumor Antigen Heterogeneity: The “Elephant in the Room” of Adoptive T-cell Therapy for Solid Tumors (2020) (3)
- Clinical conference on management dilemmas. An expanding right upper lobe cavity. (1996) (3)
- Perspectives in endothelial cell biology. (1987) (3)
- A Novel Small-Molecule Inhibitor of Transforming Growth Factor B Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection (2007) (2)
- IL-21 promotes the expansion of CD27+CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells (2013) (2)
- tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells (2013) (2)
- Abstract 60: Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment (2021) (2)
- Ligand-Induced Degradation of a CAR Permits Reversible Remote Control of CAR T Cell Activity In Vitro and In Vivo. (2020) (2)
- 15. Role of Growth Factors in Pulmonary Hypertension (1990) (2)
- Miniatures Mesothelin-Speci fi c Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies (2014) (2)
- Molecular imaging to identify tumor recurrence following chemoradiation in a hostile surgical environment. (2014) (2)
- The Role of Tumor-Associated Macrophages and Other Innate Immune Cells in Metastatic Progression of Lung Cancer (2009) (2)
- Abstract A3: Enhanced effector responses in CAR-redirected CD8+ T cells deficient in diacylglycerol kinases. (2013) (2)
- Cd31 pecam 1 is an adhesion amplifier on unique t cell subsets (1992) (2)
- Abstract A02: The origin and role of APC-like hybrid tumor-associated neutrophils in early-stage human lung cancer (2016) (2)
- Phase I study of autologous T cells bearing fully-humanized chimeric antigen receptors targeting mesothelin in mesothelin- expressing cancers (314) (2022) (2)
- Modulation of adhesion molecules by cytokinesin vivo using human/severe combined immunodeficient (SCID) mouse chimeras (1995) (2)
- Author Correction: Targeting cardiac fibrosis with engineered T cells (2019) (2)
- Abstract 3749: Genetic blockade of the protein tyrosine phosphatase SHP1 augments CAR T cell activity against PDL1 expressing solid tumors (2017) (2)
- Abstract 1291: Tumor-infiltrating FOXP3+ T-regulatory (Treg) cells in early-stage human lung cancer exhibit enhanced suppressive function when compared to blood or lymph node (LN) Treg cells (2015) (1)
- Abstract 4842: p300 targeting impairs treg function and promotes host anti-tumor immunity (2012) (1)
- Phase II trial of anti-transforming growth factor-beta (TGFß) monoclonal antibody GC1008 in relapsed malignant pleural mesothelioma (MPM). (2012) (1)
- Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells (2022) (1)
- Soluble Type II Transforming Growth Factor-β Receptor Inhibits Tumorigenesis by Augmenting Host Antitumor Immunity (2008) (1)
- Combination of Immunotherapy with Radiofrequency Ablation for Head and Neck Cancer (2005) (1)
- 220 A novel small molecule inhibitor of TGFβ type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection (2006) (1)
- Targeting cardiac fibrosis with engineered T cells (2019) (1)
- Personalizing treatment with pemetrexed (PEM) in patients with malignant mesothelioma (MPM) and non-small cell lung cancer (NSCLC): The role of thimidylate synthase. (2010) (1)
- Gene signature of antigen processing and presentation machinery (APM) as highly predictive of response to checkpoint blockade in lung cancer and melanoma. (2020) (1)
- Cancer from Patients with Nonmalignant Lung Disease Small Cell Lung − Cells Can Distinguish Patients with Non Gene Expression Profiles in Peripheral Blood Mononuclear (2009) (1)
- Abstract 3187: Depleting cells expressing fibroblast activation protein disrupts tumor-promoting desmoplasia (2015) (1)
- Expression of Urokinase-Type Plasminogen Activator in Platelets Decreases Oxygen-Induced Lung Injury in Mice. (2004) (1)
- Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD81 Cells (2011) (1)
- Circulating tumor cells (CTCs) in patients (pts) with small cell lung cancer (SCLC) as a marker of disease burden and therapeutic response, and predictor of disease relapse. (2012) (1)
- Corrigendum to “Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy” [Eur. J. Cancer 46(9) (2010) 1724-1734] (2010) (1)
- Protects Injury-Induced Lung Thrombosis and Inflammation (2009) (1)
- Effect of retinoic acid on the bystander effect in gene therapy using the Herpes Simplex Virus thymidine kinase (1997) (1)
- Abstract 3602: Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype (2022) (0)
- Personalized Medicine In Malignant Mesothelioma: Can Thymidylate Synthase And Excision Repair Cross-Complementation Group 1 Predict Response To Chemotherapy? (2011) (0)
- Gene therapy in pleural diseases (2008) (0)
- Loss Of The Transforming Growth Factor-Beta (TGF-) Receptor In The Mutated K-RAS Orthotopic Model Of Murine Lung Cancer Parallels The Progression Of Human Bronchioloalveolar Cell Carcinoma To Invasive Adenocarcinoma (2011) (0)
- Banked RBCs Increase Endothelial Cell Oxidative Stress through Advanced Glycation Endproducts. (2009) (0)
- Abstract A68: Tumor-associated neutrophils (TAN) develop protumorigenic properties during tumor progression. (2013) (0)
- Inhibition of p300 impairs Foxp3+ T-regulatory (Treg) function and promotes anti-tumor immunity (127.40) (2012) (0)
- Safety of intrapleural adenoviral gene therapy: Prelude to clinical trial for malignant mesothelioma (1996) (0)
- Augmenting adoptive transfer of T-cells by inhibiting TGF-beta (2007) (0)
- 151 Discovery and validation of novel serological biomarkers of mesothelioma (2006) (0)
- Abstract 2294: Reversible regulation of chimeric antigen receptor surface expression (2016) (0)
- endothelial luminal surface : Presented in part as posters at the ICAM-directed vascular immunotargeting of antithrombotic agents to the (2013) (0)
- Tumor Immunity toward a Type 2 Response Suppressor Cells and Macrophages Subverts Cross-Talk between Myeloid-Derived (2007) (0)
- A novel, sensitive, quantitative method for detecting tumor burden in orthotopic mouse K-ras lung cancer models (2005) (0)
- 1106. Results of a Phase I Clinical Trial of Adenoviral-Interferon-Beta Gene Therapy for Malignant Mesothelioma and Malignant Pleural Effusions (2006) (0)
- Vascular immunotargeting to lung graft endothelium (2002) (0)
- Abstract B19: FAP CAR T cell therapy for solid tumors with PET imaging (2022) (0)
- Use of Gene Therapy to Studylung Diseases (2002) (0)
- P-133 Synergy of radiotherapy and adenovirus mediated interleukin 12 gene therapy in the treatment of mouse lung tumors (2005) (0)
- Ad.interferon beta is effective in a murine orthotopic model of bronchioloalveolar lung cancer via NK cell and CD8+ T-cell mediated effects (2005) (0)
- Abstract 3790: Human tumor-infiltrating monocytes/macrophages do not predominantly inhibit tumor-specific effector T cell responses in early-stage lung cancer: The role of macrophage versus tumor PD-L1 (2018) (0)
- 925 T cell-myocyte interactions in airway inflammation (1996) (0)
- Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms (2018) (0)
- Block In Vivo Neutrophil Recruitment PECAM-1-Dependent Homophilic Adhesion Molecule-1 (PECAM-1) That Inhibit of Human Platelet Endothelial Cell Adhesion Antibodies Against the First Ig-Like Domain (1999) (0)
- The Optical Biopsy: A Novel Technique for Rapid Intraoperative onary Adenocarcinomas Diagnosis of Primary Pulm (2015) (0)
- Abstract 3142: Inhibition of the transcription factor Ikaros augments the tumoricidal capacity of CD8+ T cells expressing chimeric antigen receptors (2015) (0)
- Abstract 2936: INCA33890, a novel PD-1×TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1 (2023) (0)
- Abstract B78: Histamine dihydrochloride in the treatment of mesothelioma (2015) (0)
- Gene Expression Profiling of Malignant Mesothelioma 1 (2003) (0)
- Sub-lethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by CTL (2005) (0)
- Novel Synthetic lignan reduces asbestos-induced damage in human pleural mesothelial cells-Potential clinical usefulness in inhibiting pleural malignant mesothelioma (2017) (0)
- Neutrophils inhibit tumor growth at early stages of tumor formation. (P2006) (2013) (0)
- Repeat Intrapleural Adenoviral Interferon-ß Gene Therapy Via Tunnelled Catheter for Mesothelioma and Malignant Pleural Effusions. (2009) (0)
- Abstract 3550: Curcumin suppresses growth of human mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis (2011) (0)
- 1999 Referees (1999) (0)
- Abstract 5600: Macrophage activation and differentiation augment immunotherapy of established mouse lung tumors (2010) (0)
- P2.04-02 Effect of Chemotherapy, Chemoimmunotherapy, and Immunotherapy on Parameters of T Cell Exhaustion in Metastatic Non-Small Cell Lung Cancer (2019) (0)
- ression of Human Disseminated Tumor (2010) (0)
- Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells (2022) (0)
- CHAPTER 32 – Treatment of Mesothelioma Using Adenoviral-Mediated Delivery of Herpes Simplex Virus Thymidine Kinase Gene in Combination with Ganciclovir (2002) (0)
- The role of neoadjuvant transforming growth factor beta inhibition to prevent local recurrences and distant metastasis in advanced thoracic malignancies (2009) (0)
- Optimizing Adoptive T Cell Transfer (ACT) Immunotherapy For Malignant Pleural Mesothelioma (MPM) (2011) (0)
- 212 TGF-beta inhibition augments adenoviral-IFNbeta (Ad.IFNβ gene therapy in a murine mesothelioma model (2006) (0)
- Gene expression profiling to distinguish head and neck squamous cell carcinoma metastases from primary lung squamous cell carcinoma (2004) (0)
- Specificity and size‐dependence of immunotargeting of the anti‐PECAM/catalase conjugates to endothelium (2006) (0)
- Molecular and Cellular Properties ofPECAM-1(endoCAM/CD31) : A Novel Vascular Cell-Cell Adhesion Molecule (2002) (0)
- Focus Session 1: Targeted Drug Delivery (2014) (0)
- Detection And Use Of Circulating Tumor Cells For Biocorrelative Analysis In Patients With Small Cell Lung Cancer (2011) (0)
- Intraoperative Monitoring of Photodynamic Therapy Efficacy using Diffuse Optical Spectroscopy in Mesotheloma Patients: Focusing on the Effect of PDT-induced Hypoxia (2014) (0)
- Identification of Tissue Resident Memory CD8+ T Cells in Malignant Pleural Effusions Associated with Non-Small Cell Lung Cancer (0)
- Abstract A016: Selective delivery of fibroblast activation protein conjugated dual phosphoinositide 3-kinase–AKT Kinase-mTOR inhibitor associated with decreased tumor proliferation and on-target toxicity in high-grade soft-tissue sarcomas (2022) (0)
- endothelial cells production from cultured human pulmonary Endotoxin stimulates platelet-derived growth factor (2002) (0)
- Erythrocyte Advanced Glycation End-Products as Novel Mediators of Endothelial Dysfunction Following Transfusion (2012) (0)
- Curing Mesothelioma: The Long Winding Road (2012) (0)
- facilitates prophylactic thrombolysis in the pulmonary vasculature single-chain variable antibody fragment (scFv) with pro-urokinase Endothelial targeting of a recombinant construct fusing a PECAM-1 (2013) (0)
- Abstract B12: Inhibition of the transcription factor Ikaros augments the tumoricidal capacity of CD8+ T cells expressing chimeric antigen receptor (2015) (0)
- Abstract A62: Inhibition of tumor growth by novel CART redirected against cells expressing high levels of fibroblast activation protein (2020) (0)
- Early stage human lung tumors give rise to a subpopulation of tumor-associated neutrophils with the composite characteristics of neutrophils and antigen-presenting cells (TUM10P.1042) (2015) (0)
- Supplemental Information Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer (0)
- Prevention Of Influenza Pneumonia By Direct Induction Of The Epithelial Interferon Regulatory Factor 3-interferon Pathway Through Inhalation Of The Flavanoid-like Compound 5’6’-dimethylxanthenone-4-acetic Acid (DMXAA) (2010) (0)
- Adenovirus-mediated gene therapy for malignant mesothelioma: A comparison of immunosuppressed, immunodeficient and immunocompetent tumor models (1996) (0)
- Abstract B27: Blockade of protein kinase A (PKA) localization augments the trafficking and anti-tumor efficacy of adoptively transferred chimeric antigen receptor-expressing T cells (2016) (0)
- P3.03-027 Growth Factor and Inflammatory Signaling Pathway Interactions Influence Outcomes Following Multimodality Therapy for Mesothelioma: Topic: Mesothelioma Transitional (2017) (0)
- Abstract 972: Anchoring Of Thrombomodulin On Endothelium Protects Against Mouse Lung Ischemia-reperfusion Injury (2007) (0)
- Abstract A67: Augmented antitumor activity of NK-92 MI cells expressing a chimeric antigen receptor targeting human mesothelin (2020) (0)
- 1108. High Rate of Anti-Tumor Immune Responses in a Phase 1 Clinical Trial of Adenoviral-Interferon-Beta Gene Transfer for Malignant Mesothelioma (MM) and Malignant Pleural Effusions (MPE) (2006) (0)
- Disruption of desmoplastic stroma overcomes restrictions to T cell extravasation, immune exclusion and immunosuppression in solid tumors (2023) (0)
- Abstract 2566: Beneficial impact of valproate on the response of small cell lung cancer to cisplatin – etoposide therapy (2011) (0)
- A PILOT AND FEASIBILITY CLINICAL TRIAL EVALUATING IMMUNO-GENE THERAPY OF MALIGNANT PLEURAL MESOTHELIOMA (MPM) USING INTRAPLEURAL DELIVERY OF ADENOVIRUS- INTERFERON-ALPHA (Ad.hIFN-α2b) IN COMBINATION WITH HIGH-DOSE CELECOXIB AND SYSTEMIC CHEMOTHERAPY (2016) (0)
- Abstract 1585: T-regulatory cells impair CAR T cell-mediated antitumor activity in a murine solid tumor model (2021) (0)
- O-023 Ad.Anterferon beta is an effective treatment in an orthotopicmodel of broncho-alveolar non-small cell lung cancer via NK cell and CD 8+ T cell mechanisms (2005) (0)
- The exploitation of inflammation in photodynamic therapy of pleural cancer (Conference Presentation) (2017) (0)
- Referee Acknowledgement for 2012 (2013) (0)
- Treatment of xenograft models of human malignant mesothelioma utilizing adenovirus-mediated gene therapy (1996) (0)
- 48 Altering the tumor microenvironment to augment immunotherapy for mesothelioma (2006) (0)
- Tuberculosis and Respiratory Diseases : Thematic Poster ; Retinoid Augment the Bystander Effect in HSVtk/GCV Mediated Gene Therapy by Enhanced Gap Junctional Intercellular Communcation (1996) (0)
- Experimental Production andModulation of HumanCytotoxic Dermatitis inHuman-Murine (1997) (0)
- The Integrin Cell Adhesion Molecules (2017) (0)
- 4-1BB-Costimulated CAR-Mediated Non-Canonical NF-Kb Signaling Enhances CAR T Cell Survival and Suppresses Bim Expression (2018) (0)
- Molecular Characterization Of Tumor Associated Neutrophils From Non Small Cell Lung Cancer (NSCLC) And Mesothelioma Tumors (2011) (0)
- Lung Adenocarcinoma Stromal Invasion Biomarkers Thrombospondin-2 And Platelet-Derived Growth Factor Receptor-Beta Are Associated With Poor Survival (2011) (0)
- Abstract A03: Inhibition of the histone/protein acetyltransferase, Tip60, impairs Foxp3 acetylation and Treg function and thereby promotes antitumor immunity (2016) (0)
- Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response 1 (2007) (0)
- Abstract 5164: Protein kinase C epsilon is a mediator of KRAS-driven lung tumorigenesis (2016) (0)
- 572. Augmentation of Immuno-Gene Therapy for Lung Cancer Using Chemotherapy (2004) (0)
- Abstract 5542: Flaxseed and its lignan component protect from asbestos-induced inflammation in mice (2015) (0)
- Anti-CCL2 Antibodies Decrease Spontaneous Metastatic Disease in a Model of NSCLC. (2009) (0)
- Modulation of cancer immunobiology to prevent recurrences following surgery for non-small cell lung cancer (NSCLC) (2010) (0)
- Cell Adhesion Molecules (2002) (0)
- Synergy of Anti-CCL2 Antibodies and Tumor-Vaccination in the Treatment of Established Mouse Lung Tumors. (2009) (0)
- Cancer esearch oenvironment and Immunology tiple Injections of Electroporated Autologous T Cells ressing a Chimeric Antigen Receptor Mediate R ression of Human Disseminated Tumor (2010) (0)
- Abstract 3201: Identification of the type 2 cystatins (SA/SN) as a novel biomarkers for stress-induced senescence in human non-small cell lung cancer lines (2010) (0)
- Abstract PR14: Fibroblast activation protein as a universal target for chimeric antigen receptor T cell therapy in solid tumors. (2013) (0)
- Abstract 1513: Pre-clinical evaluation of two oncolytic viral vectors expressing IFNβ in treatment of thoracic cancer: Vaccinia virus versus vesicular stomatitis virus (2010) (0)
- Abstract 1641: Dual antibody blockade of TIM3 and PD1 on NYESO1 redirected human T cells leads to augmented control of lung cancer tumors (2017) (0)
- The Impact of Surgically Induced Inflammation on Outcomes Following Intraoperative Photodynamic Therapy in Patients with Thoracic Malignancies (2023) (0)
- 1129. Ad.Interferon Beta Is an Effective Treatment in an Orthotopic Model of Broncho-Alveolar Non-Small Cell Lung Cancer Via NK Cell and CD 8+ T Cell Mechanisms (2005) (0)
- Activation Of Pulmonary Endothelial Cells By Banked RBCs And LPS (2010) (0)
- Targeted Delivery of Catalase to the Pulmonary Endothelium Preserves Graft Function of Non-Heart-Beating Donor Lungs in Pigs. (2009) (0)
- Integrin Receptors in Wound-Induced Human (2007) (0)
- P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM) (2017) (0)
- PO-387 Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes (TILs) (2018) (0)
- targeted to PECAM-1 in the pulmonary vasculature Prophylactic thrombolysis by thrombin-activated latent pro-urokinase (2013) (0)
- A Preclinical Model Tto Study Tumor-Infiltrating Lymphocyte (TIL) Anergy/Exhaustion In Adoptive T Cell Therapy (ACT) Of Thoracic Malignancies (2012) (0)
- Abstract 3707: Tumor-associated neutrophils with antigen-presenting features in early-stage human lung cancer (2017) (0)
- Neoadjuvant endobronchial delivery of gene mediated cytotoxic immunotherapy (GMCI) for non-small cell lung cancer (NSCLC): Safety and immunologic activity. (2020) (0)
- Abstract A66: Tumor-associated neutrophils in early stage human lung cancer are not immunosuppressive, but exhibit an inflammatory phenotype and provide accessory signals for T cell activation (2015) (0)
- Expression of IFN- B Enhances Both Efficacy and Safety of Oncolytic Vesicular Stomatitis Virus for Therapy of Mesothelioma Experimental Therapeutics, Molecular Targets, and Chemical Biology (2009) (0)
- Abstract 4706: TCR engineered adoptive T-cell therapy for lung cancer is augmented by combined PD1 and TIM3 antibody blockade (2015) (0)
- P-402 An immunologic assessment of a phase I clinical trialof adenoviral interferon-beta for the treatment of pleural malignancies (2005) (0)
- Abstract 4293: Histamine dihydrochloride as an immune modulator for solid tumors (2015) (0)
- 207 Results of phase I clinical trials of adenoviral interferon-β gene therapy for malignant mesothelioma and malignant pleural effusions (2006) (0)
- Banked RBCs Induce The Expression Of The Receptor For Advanced Glycation Endproducts (RAGE) On Lung Endothelial Cells (2012) (0)
- Curcumin inhibits allergen-sensitized lymphocyte function ex vivo and in vitro (2005) (0)
- Alveolar Destruction And Airspace Enlargement In TSC2-Null Murine Model Of LAM And Its Therapeutic Targeting (2012) (0)
- Use of Gene Therapy to Treat Lung Diseases (2002) (0)
- Abstract 1912: Significant changes in chemokine genes in tumor-associated neutrophils (TANs) using a microarray approach (2010) (0)
- In Situ Vaccination with Adenoviral Vectors to Treat Cancer (2016) (0)
- The timing of TGF-β inhibition affects the generation of antigen-specific CD8+ T Cells (2013) (0)
- Peripheral Blood Mononuclear Cell Gene Expression And Survival In Non-Small Cell Lung Cancer (2011) (0)
- 21. Non-CD3-Based Chimeric Antigen Receptor (CARs) with Enhanced Anti-Tumor Activity in Solid Tumors (2015) (0)
- Myeloperoxidase as an immunomodulator in intraoperative photodynamic therapy (Conference Presentation) (2018) (0)
- Synthesis of the stable isotope labeled antiviral nucleoside analog [8‐13C–7,9‐15N2]‐ganciclovir (2006) (0)
- causes oxidative vascular injury in the lungs Immunotargeting of glucose oxidase to endothelium in vivo (2013) (0)
- Abstract 4142: Fibroblast activation protein transmembrane receptor targeted near-infrared fluorochrome specifically identifies patient derived lung cancer associated fibroblasts in pre-clinical models (2022) (0)
- endothelial luminal surface ICAM-directed vascular immunotargeting of anti-thrombotic agents to (2003) (0)
- Abstract 1013: Location matters: unique functional and transcriptional, but not flow cytometric, characteristics of intratumoral FOXP3+ Tregs vs. Tregs from other sites of patients with lung tumors (2017) (0)
- The expression of WT1 in malignant mesothelioma and its utility in the differential diagnosis of pleural-based lesions (1996) (0)
- Abstract B22: A chimeric antigen receptor (CARs) based upon a killer immunoglobulin-like receptor (KIR) triggers robust cytotoxic activity in solid tumors (2015) (0)
- of Human Disseminated Tumor Expressing a Chimeric Antigen Receptor Mediate Regression Multiple Injections of Electroporated Autologous T Cells (2010) (0)
- Abstract 1236: Upregulation of stem cell markers in senescent lung cancer cells following chemotherapy (2011) (0)
- Correction: CCL2 Blockade Augments Cancer Immunotherapy (2010) (0)
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What Schools Are Affiliated With Steven Mark Albelda?
Steven Mark Albelda is affiliated with the following schools:
