Steven m. Rothman
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Steven m. Rothmanphilosophy Degrees
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#11371
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Logic
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Steven m. Rothmanbiology Degrees
Biology
#10881
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Neuroscience
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#1785
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Why Is Steven m. Rothman Influential?
(Suggest an Edit or Addition)Steven m. Rothman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Glutamate and the pathophysiology of hypoxic–ischemic brain damage (1986) (2476)
- The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. (1990) (2245)
- Excitotoxity and the NMDA receptor (1987) (1080)
- Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death (1984) (895)
- The neurotoxicity of excitatory amino acids is produced by passive chloride influx (1985) (627)
- Excitotoxicity and the NMDA receptor - still lethal after eight years (1995) (572)
- Synaptic activity mediates death of hypoxic neurons. (1983) (441)
- Delayed neurotoxicity of excitatory amino acids In vitro (1987) (349)
- Outcomes after allogeneic hematopoietic cell transplantation for childhood cerebral adrenoleukodystrophy: the largest single-institution cohort report. (2011) (241)
- Ionic Mechanism of Ouabain-Induced Concurrent Apoptosis and Necrosis in Individual Cultured Cortical Neurons (2002) (238)
- Sickle cell anemia and central nervous system infarction: A neuropathological study (1986) (223)
- Ionized Intracellular Calcium Concentration Predicts Excitotoxic Neuronal Death: Observations with Low-Affinity Fluorescent Calcium Indicators (1997) (191)
- Kainate Seizures Cause Acute Dendritic Injury and Actin Depolymerization In Vivo (2007) (144)
- CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis. (2006) (132)
- Blockade of excitatory amino acid receptors protects anoxic hippocampal slices (1987) (130)
- Decision‐Making for Termination of Pregnancies With Fetal Anomalies: Analysis of 53,000 Pregnancies (2002) (127)
- Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. (1981) (123)
- Ketamine protects hippocampal neurons from anoxia in vitro (1987) (118)
- Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. (2008) (113)
- Neocortical Seizure Termination by Focal Cooling: Temperature Dependence and Automated Seizure Detection (2002) (100)
- Prolonged Exposure to Levetiracetam Reveals a Presynaptic Effect on Neurotransmission (2007) (100)
- A new mechanism for antiepileptic drug action: vesicular entry may mediate the effects of levetiracetam. (2011) (94)
- Focal cooling rapidly terminates experimental neocortical seizures (2001) (88)
- Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons (1994) (84)
- 3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: a new class of anticonvulsant agents. (1996) (69)
- Mild passive focal cooling prevents epileptic seizures after head injury in rats (2013) (66)
- Impact of epilepsy surgery on seizure control and quality of life: A 26‐year follow‐up study (2012) (64)
- Rapid Cooling Aborts Seizure‐Like Activity in Rodent Hippocampal‐Entorhinal Slices (2000) (64)
- Cooling blocks rat hippocampal neurotransmission by a presynaptic mechanism: observations using 2‐photon microscopy (2005) (63)
- Rapid desensitization determines the pharmacology of glutamate neurotoxicity (1994) (62)
- Cooling produces minimal neuropathology in neocortex and hippocampus (2006) (59)
- Excitotoxins: Possible Mechanisms of Action a (1992) (58)
- Nordihydroguaiaretic acid attenuates NMDA neurotoxicity—Action beyond the receptor (1993) (58)
- In vivo imaging of dendritic spines during electrographic seizures (2005) (54)
- Focal cooling for epilepsy: An alternative therapy that might actually work (2005) (54)
- The therapeutic potential of focal cooling for neocortical epilepsy (2009) (52)
- Physiology of excitatory synaptic transmission in cultures of dissociated rat hippocampus. (1985) (52)
- Levetiracetam has an activity‐dependent effect on inhibitory transmission (2012) (52)
- Noncompetitive N-methyl-D-aspartate antagonists affect multiple ionic currents. (1988) (47)
- The Estrogen Receptor Is Not Essential for All Estrogen Neuroprotection: New Evidence from a New Analog (2002) (44)
- Early diagnosis of cerebral X-linked adrenoleukodystrophy in boys with Addison’s disease improves survival and neurological outcomes (2011) (43)
- Cerebrovascular Changes in Neurofibromatosis (1978) (43)
- Risk factors for EEG seizures in neonates treated with hypothermia: A multicenter cohort study (2014) (42)
- Brivaracetam augments short‐term depression and slows vesicle recycling (2015) (41)
- Contribution of Subsaturating GABA Concentrations to IPSCs in Cultured Hippocampal Neurons (1998) (40)
- Spinal cord infarction in a patient with sickle cell anemia (1980) (39)
- Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3-benzyl-2-piperidinones (δ-Valerolactams) and Hexahydro-2H-azepin-2-ones (ε-Caprolactams) (1997) (39)
- A scanning electron microscope study of the in vitro development of dissociated hippocampal cells (1981) (39)
- Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices (1998) (36)
- Levetiracetam has a time- and stimulation-dependent effect on synaptic transmission (2009) (35)
- Reversible Physiological Alterations in Sympathetic Neurons Deprived of NGF but Protected from Apoptosis by Caspase Inhibition or Bax Deletion (2000) (35)
- Long‐lasting Anticonvulsant Effect of Focal Cooling on Experimental Neocortical Seizures (2003) (33)
- Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy (2011) (33)
- Pediatric neuroenhancement: Ethical, legal, social, and neurodevelopmental implications (2013) (32)
- Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones. (1994) (31)
- Lactone Modulation of the γ-Aminobutyric Acid A Receptor: Evidence for a Positive Modulatory Site (1997) (29)
- Multiple Channel Interactions Explain the Protection of Sympathetic Neurons from Apoptosis Induced by Nerve Growth Factor Deprivation (2002) (28)
- Transcortical Cooling Inhibits Hippocampal‐kindled Seizures in the Rat (2005) (27)
- Structure-activity studies of fluoroaljyl-substituted γ-butyrolactone and γ-thiobutyrolactone modulators of GABAA receptor function (1998) (27)
- Glutamate and anoxic neuronal death in vitro. (1986) (25)
- Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist. (1991) (24)
- The unilateral cobalt wire model of neocortical epilepsy: a method of producing subacute focal seizures in rodents (2004) (24)
- Local Cooling: A Therapy for Intractable Neocortical Epilepsy (2003) (23)
- Optical control of focal epilepsy in vivo with caged γ‐aminobutyric acid (2012) (23)
- Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones. (1995) (22)
- Inhibition of voltage-dependent sodium channels by the anticonvulsant gamma-aminobutyric acid type A receptor modulator, 3-benzyl-3-ethyl-2-piperidinone. (1998) (20)
- Intracerebral temperature alterations associated with focal seizures (2002) (18)
- Optical suppression of experimental seizures in rat brain slices (2010) (18)
- Congenital astrocytoma presenting with intracerebral hematoma. Case report. (1979) (17)
- Optical suppression of seizure-like activity with an LED (2007) (16)
- Physiological comparison of α-ethyl-α-methyl-γ-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors (1996) (15)
- Excitotoxic neuronal death: mechanisms and clinical relevance (1994) (15)
- Electrophysiology of duchenne dystrophy myotubes in tissue culture (1983) (15)
- Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons (1990) (14)
- Mitochondrial Morphology and Intracellular Calcium Homeostasis in Cytochrome Oxidase-Deficient Human Fibroblasts (1997) (14)
- Development of Phase Change Heat Spreader for Treatment of Intractable Neocortical Epilepsy (2007) (14)
- Focal cooling devices for the surgical treatment of epilepsy. (2011) (14)
- Mutations of the mitochondrial genome: clinical overview and possible pathophysiology of cell damage. (1999) (14)
- 3,3‐Dialkyl‐ and 3‐Alkyl‐3‐benzyl‐Substituted 2‐Pyrrolidinones: A New Class of Anticonvulsant Agents. (1996) (11)
- Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling. (2015) (11)
- Stroke in children: Freud's first analysis (2002) (10)
- What bulges under a bulging fontanel? (1998) (10)
- Epilepsy: an anticipatory presentation of pediatric Wegener's granulomatosis. (2010) (8)
- Modulation of the picrotoxin receptor by fluorinated ethyl, methyl-butyrolactones. (1990) (8)
- Glutamine currents in hippocampal neurons are attributable to contaminating glutamate (1989) (8)
- Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site. (1997) (7)
- Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation (1999) (6)
- Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function. (1998) (6)
- Pediatric neurology’s midlife crisis (2004) (5)
- Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams). (1997) (4)
- Seletracetam enhances short term depression in vitro (2015) (3)
- In Vitro Neuronal Death: Contrasts Between Excitotoxicity and Chemical Hypoxia (1991) (2)
- Focal Cortical Cooling (2005) (2)
- Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors. (1996) (2)
- Regarding the beautiful and ethereal neurological exam (2012) (1)
- Beyond Prediction – Focal Cooling and Optical Activation to Terminate Focal Seizures (2008) (1)
- The Tempest ' Shakespeare ' s ' spiritual autobiography ' to enchant (2014) (0)
- Neuroimaging Rates for Closed Head Trauma in a Community Hospital (2016) (0)
- Seizure As A Unique Presentation Of Pediatric Wegener’s Granulomatosis (2010) (0)
- TREATMENTS (NON-ANTIEPILEPTIC DRUGS) | Focal Cooling as a Potential Treatment for Neocortical Epilepsies (2009) (0)
- Pediatric neurology's midlife crisis [6] (multiple letters) (2004) (0)
- Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation for Childhood Cerebral Variant Adrenoleukodystrophy: A Modern, Single-Institution Experience (2010) (0)
- cohort report childhood cerebral adrenoleukodystrophy: the largest single-institution Outcomes after allogeneic hematopoietic cell transplantation for (2011) (0)
- Mechanisms of excitotoxic neuronal death (1992) (0)
- EEG and neonatal hypothermia (2019) (0)
- S-40-3 Thiazide derivatives block rapid AMPA receptordesensitization (1996) (0)
- BULGING ANTERIOR FONTANEL. AUTHORS' REPLY (1998) (0)
- AIM, a Multi-Targeted, Combination Oral Therapy for the Gangliosidoses (2012) (0)
- Bulging Anterior Fontanel—Reply (1998) (0)
- AAV-mediated gene therapy causes functional improvements in a murine model of infantile neuronal ceroid lipofuscinosis (INCL, Batten disease) (2004) (0)
- AAV-mediated gene therapy for murine infantile Neuronal Ceroid Lipofuscinosis (INCL, Batten Disease) (2003) (0)
- Editorial Board (2011) (0)
- Pediatric neurology's midlife crisis. Author's reply (2004) (0)
- dtotoxid and the NMDA receptor (1987) (0)
- α‐Spirocyclopentyl‐ and α‐Spirocyclopropyl‐γ‐ butyrolactones: Conformationally Constrained Derivatives of Anticonvulsant and Convulsant α,α‐Disubstituted γ‐ Butyrolactones. (1994) (0)
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