Steven V. Ley
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British chemist
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Chemistry
Steven V. Ley's Degrees
- Bachelors Chemistry University of Manchester
Why Is Steven V. Ley Influential?
(Suggest an Edit or Addition)According to Wikipedia, Steven Victor Ley is Professor of Organic Chemistry in the Department of Chemistry at the University of Cambridge, and is a Fellow of Trinity College, Cambridge. He was President of the Royal Society of Chemistry and was made a CBE in January 2002, in the process. In 2011, he was included by The Times in the list of the "100 most important people in British science".
Steven V. Ley's Published Works
Published Works
- Modern Synthetic Methods for Copper‐Mediated C(aryl) ? O, C(aryl) ? N, and C(aryl) ? S Bond Formation (2003) (2069)
- Tetrapropylammonium Perruthenate, Pr4N+RuO4-, TPAP: A Catalytic Oxidant for Organic Synthesis (1994) (825)
- Targeting C-reactive protein for the treatment of cardiovascular disease (2006) (651)
- Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation (2000) (563)
- Flow chemistry syntheses of natural products. (2013) (495)
- Moderne Synthesemethoden: Kupfer-vermittelte C(Aryl)-O-, C(Aryl)-N- und C(Aryl)-S-Verknüpfungen (2003) (447)
- Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions. (2005) (390)
- Preparation and use of tetra-n-butylammonium per-ruthenate (TBAP reagent) and tetra-n-propylammonium per-ruthenate (TPAP reagent) as new catalytic oxidants for alcohols (1987) (388)
- An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals (2011) (377)
- Organic synthesis: march of the machines. (2015) (337)
- Taming hazardous chemistry by continuous flow technology. (2016) (327)
- A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly. (2006) (270)
- Flow ozonolysis using a semipermeable Teflon AF-2400 membrane to effect gas-liquid contact. (2010) (242)
- New tools and concepts for modern organic synthesis (2002) (204)
- Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations. (2006) (204)
- Tuning glycoside reactivity: New tool for efficient oligosaccharide synthesis (1998) (200)
- ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing (2010) (200)
- Enantioselective organocatalytic cyclopropanation via ammonium ylides. (2004) (197)
- Multistep synthesis using modular flow reactors: Bestmann-Ohira reagent for the formation of alkynes and triazoles. (2009) (190)
- The chemistry of azadirachtin (1993) (189)
- The continuous-flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor. (2011) (187)
- Flow chemistry: intelligent processing of gas-liquid transformations using a tube-in-tube reactor. (2015) (185)
- 5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins. (2004) (179)
- Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas-liquid contact at elevated pressure†‡ (2011) (169)
- Actions of azadirachtin, a plant allelochemical, against insects (1998) (167)
- On being green: can flow chemistry help? (2012) (165)
- Encapsulation of palladium in polyurea microcapsules. (2002) (160)
- Machine‐Assisted Organic Synthesis (2015) (159)
- Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae (1990) (153)
- A flow-based synthesis of imatinib: the API of Gleevec. (2010) (150)
- KMnO(4)-Mediated oxidation as a continuous flow process. (2010) (148)
- Enantioselective catalytic intramolecular cyclopropanation using modified cinchona alkaloid organocatalysts. (2006) (141)
- Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst. (2006) (138)
- The flow synthesis of heterocycles for natural product and medicinal chemistry applications (2011) (137)
- Synthesis of azadirachtin: a long but successful journey. (2007) (137)
- Ultrasound in Synthesis (1989) (132)
- 1,2-diacetals: a new opportunity for organic synthesis. (2001) (131)
- A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis (2015) (126)
- Organic-catalyst-mediated cyclopropanation reaction. (2003) (126)
- Development of fluorination methods using continuous-flow microreactors (2009) (124)
- Enabling Technologies for the Future of Chemical Synthesis (2016) (121)
- Microwave reactions under continuous flow conditions. (2007) (121)
- Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor (2011) (121)
- A Systems Approach towards an Intelligent and Self-Controlling Platform for Integrated Continuous Reaction Sequences** (2014) (119)
- A Microcapillary Flow Disc Reactor for Organic Synthesis (2007) (118)
- An intramolecular organocatalytic cyclopropanation reaction. (2004) (117)
- Continuous Flow-Processing of Organometallic Reagents Using an Advanced Peristaltic Pumping System and the Telescoped Flow Synthesis of (E/Z)-Tamoxifen (2013) (115)
- Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor. (2011) (114)
- Continuous flow reaction monitoring using an on-line miniature mass spectrometer. (2012) (113)
- Continuous Flow Ligand-Free Heck Reactions Using Monolithic Pd [0] Nanoparticles (2007) (113)
- Fragment-based hit identification: thinking in 3D. (2013) (112)
- A Facile One-Pot Synthesis of a Trisaccharide Unit from the Common Polysaccharide Antigen of Group B Streptococci Using Cyclohexane-1, 2-diacetal (CDA) Protected Rhamnosides† (1994) (109)
- Polyurea-encapsulated palladium(II) acetate: a robust and recyclable catalyst for use in conventional and supercritical media. (2002) (108)
- A modular flow reactor for performing Curtius rearrangements as a continuous flow process. (2008) (107)
- Microbial oxidation in synthesis: A six step perparation of (+)-pinitol from benzene (1987) (107)
- Heterogeneous or Homogeneous? A Case Study Involving Palladium‐Containing Perovskites in the Suzuki Reaction (2005) (107)
- Teflon AF-2400 mediated gas-liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration. (2011) (107)
- Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases. (2000) (106)
- Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide. (2014) (106)
- Accelerating spirocyclic polyketide synthesis using flow chemistry. (2014) (106)
- Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring (2012) (104)
- Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions. (2008) (102)
- A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures. (2011) (102)
- A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia. (2013) (101)
- N-alkylation of indole and pyrroles in dimethyl sulphoxide (1973) (101)
- The use of a continuous flow-reactor employing a mixed hydrogen-liquid flow stream for the efficient reduction of imines to amines. (2005) (100)
- Total synthesis of the amaryllidaceae alkaloid (+)-plicamine and its unnatural enantiomer by using solid-supported reagents and scavengers in a multistep sequence of reactions. (2002) (100)
- Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(sp2)–C(sp3) Cross‐Couplings in Flow (2016) (100)
- Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor. (2010) (100)
- Flow chemistry synthesis of zolpidem, alpidem and other GABAA agonists and their biological evaluation through the use of in-line frontal affinity chromatography (2013) (100)
- A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones. (2005) (99)
- [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor. (2007) (99)
- Tetra-n-propylammonium perruthenate (TPAP)-catalysed oxidations of alcohols using molecular oxygen as a co-oxidant (1997) (96)
- The oxygen-mediated synthesis of 1,3-butadiynes in continuous flow: using Teflon AF-2400 to effect gas/liquid contact. (2012) (96)
- Recyclable polyurea-microencapsulated Pd(0) nanoparticles: an efficient catalyst for hydrogenolysis of epoxides. (2003) (95)
- A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing† (2011) (95)
- Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles. (2006) (94)
- Further reactions of t-butyl 3-oxobutanthioate and t-butyl 4-diethyl-phosphono-3-oxobutanthioate : Carbonyl coupling reactions, amination, use in the preparation of 3-acyltetramic acids and application to the total synthesis of fuligorubin A. (1992) (94)
- A prototype continuous-flow liquid-liquid extraction system using open-source technology. (2012) (94)
- Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes (2013) (94)
- Flow chemistry meets advanced functional materials. (2014) (94)
- Sexual development of malaria parasites is inhibited in vitro by the neem extract azadirachtin, and its semi-synthetic analogues. (1994) (91)
- Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts. (2005) (90)
- The antifeedant activity of clerodane diterpenoids from Teucrium (1989) (90)
- Polymer supported perruthenate (PSP): a new oxidant for clean organic synthesis (1997) (89)
- The Changing Face of Organic Synthesis (2008) (88)
- Transfer hydrogenation using recyclable polyurea-encapsulated palladium: efficient and chemoselective reduction of aryl ketones. (2003) (87)
- A route to the thapsigargins from (S)-carvone providing a substrate-controlled total synthesis of trilobolide, nortrilobolide, and thapsivillosin F. (2003) (87)
- A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles. (2011) (86)
- Multi-step synthesis by using modular flow reactors: the preparation of yne--ones and their use in heterocycle synthesis. (2010) (86)
- An x-ray crystallographic, mass spectroscopic, and NMR study of the limonoid insect antifeedant azadirachtin and related derivatives (1987) (85)
- Continuous multiple liquid-liquid separation: diazotization of amino acids in flow. (2012) (85)
- The rapid preparation of 2-aminosulfonamide-1,3,4-oxadiazoles using polymer-supported reagents and microwave heating (2005) (83)
- Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito. (2001) (83)
- Three-step synthesis of an array of substituted benzofurans using polymer-supported reagents (1999) (82)
- A highly selective, organocatalytic route to chiral dihydro-1,2-oxazines. (2005) (82)
- Total synthesis of the amaryllidaceae alkaloid (+)-plicamine using solid-supported reagents (2002) (82)
- Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme (2011) (81)
- Substitution reactions of 2-benzenesulphonyl cyclic ethers with carbon nucleophiles (1989) (81)
- Microencapsulation of osmium tetroxide in polyurea. (2003) (81)
- PtCl4-catalyzed domino synthesis of fused bicyclic acetals. (2008) (81)
- A continuous flow process using a sequence of microreactors with in-line IR analysis for the preparation of N,N-diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a potent and highly selective δ-opioid receptor agonist. (2010) (80)
- Total synthesis of the anthelmintic macrolide avermectin B1a (1991) (80)
- Total synthesis of the ionophore antibiotic CP-61,405 (routiennocin) (1992) (80)
- Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition. (2007) (80)
- Flow synthesis using gaseous ammonia in a Teflon AF-2400 tube-in-tube reactor: Paal-Knorr pyrrole formation and gas concentration measurement by inline flow titration. (2012) (80)
- The azadirachtin story. (2008) (79)
- A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds** (2015) (79)
- Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent. (2011) (79)
- A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters (2017) (78)
- Modified mesoporous silicate MCM-41 materials: immobilised perruthenate—a new highly active heterogeneous oxidation catalyst for clean organic synthesis using molecular oxygen (1999) (77)
- Total synthesis of the anti-apoptotic agents iso- and bongkrekic acids. (2010) (77)
- Synthesis of the alkaloids (±)-oxomaritidine and (±)-epimaritidine using an orchestrated multi-step sequence of polymer supported reagents (1999) (77)
- Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia (2016) (76)
- Dispiroketals in synthesis (Part 5): A new opportunity for oligosaccharide synthesis using differentially activated glycosyl donors and acceptors (1993) (76)
- A concise synthesis of carpanone using solid-supported reagents and scavengers (2002) (75)
- An expeditious synthesis of imatinib and analogues utilising flow chemistry methods. (2013) (75)
- Microwave assisted Leimgruber-Batcho reaction for the preparation of indoles, azaindoles and pyrroylquinolines. (2004) (75)
- Iterative reactions of transient boronic acids enable sequential C-C bond formation. (2016) (74)
- Oxidation Adjacent to Oxygen of Alcohols by Chromium Reagents (1991) (74)
- Diaryl telluroxides as new mild oxidising reagents (1981) (73)
- Flow chemistry as a discovery tool to access sp2–sp3 cross-coupling reactions via diazo compounds† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03072a Click here for additional data file. (2014) (73)
- Flow and batch mode focused microwave synthesis of 5-amino-4-cyanopyrazoles and their further conversion to 4-aminopyrazolopyrimidines. (2007) (73)
- An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones. (2006) (73)
- Azadirachtin Disrupts Formation of Organised Microtubule Arrays during Microgametogenesis of Plasmodium berghei (2002) (73)
- (pi-Allyl)tricarbonyliron Lactone Complexes in Organic Synthesis: A Useful and Conceptually Unusual Route to Lactones and Lactams. (1996) (72)
- A highly convergent total synthesis of the spiroacetal macrolide (+)-milbemycinβ1 (1989) (72)
- Alkylation reactions of anions derived from 2-benzenesulphonyl tetrahydropyran and their application to spiroketal syntiesis (1986) (71)
- A general organocatalytic enantioselective malonate addition to alpha,beta-unsaturated enones. (2008) (71)
- Microbial oxidation in synthesis: preparation of myo-inositol phosphates and related cyclitol derivatives from benzene (1990) (71)
- Polymer-supported hypervalent iodine reagents in ‘clean’ organic synthesis with potential application in combinatorial chemistry (1999) (71)
- Synthesis of the C-1-C-28 ABCD unit of spongistatin 1. (2003) (71)
- Polymer-supported reagents for multi-step organic synthesis: application to the synthesis of sildenafil. (2000) (71)
- A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols. (2006) (70)
- A polymer-supported thionating reagent (2001) (70)
- Neo-clerodane insect antifeedants from Scutellaria galericulata (1990) (70)
- Rotamers or diastereomers? An overlooked NMR solution. (2012) (70)
- Synthesis of the potent analgesic compound (±)-epibatidine using an orchestrated multi-step sequence of polymer supported reagents (1999) (70)
- Metal-free coupling of saturated heterocyclic sulfonylhydrazones with boronic acids. (2014) (69)
- An electrophysiological and behavioural study of insect antifeedant properties of natural and synthetic drimane‐related compounds (1987) (69)
- Direct preparation of diacetals from 1,2-diketones and their use as 1,2-diol protecting groups (1997) (69)
- Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives. (2006) (69)
- Rapid Assembly of Oligosaccharides: Total Synthesis of a Glycosylphosphatidylinositol Anchor of Trypanosoma brucei. (1998) (69)
- Highly selective entry to the azadirachtin skeleton via a Claisen rearrangement/radical cyclization sequence. (2002) (69)
- The application of flow microreactors to the preparation of a family of casein kinase I inhibitors. (2010) (69)
- Oxo complexes of ruthenium(VI) and (VII) as organic oxidants (1984) (68)
- X-ray crystallographic structure determination of detigloyldihydroazadirachtin and reassignment of the structure of the limonoid insect antifeedant azadirachtin (1986) (68)
- Synthesis of a hydroxy dihydrofuran acetal related to azadirachtin: A potent insect antifeedant (1987) (67)
- Polymer Supported Perruthenate (PSP): Clean Oxidation of Primary Alcohols to Carbonyl Compounds Using Oxygen as Cooxidant (1998) (67)
- Asymmetric Homogeneous Hydrogenation in Flow using a Tube-in-Tube Reactor (2012) (66)
- 1,2-Diacetals in synthesis: total synthesis of a glycosylphosphatidylinositol anchor of Trypanosoma brucei. (2000) (66)
- Clerodane diterpenoids. (1992) (66)
- Non-metal-catalysed intramolecular alkyne cyclotrimerization reactions promoted by focussed microwave heating in batch and flow modes. (2005) (66)
- Palladium-containing perovskites: recoverable and reuseable catalysts for Suzuki couplings. (2003) (65)
- Total synthesis of the ionophore antibiotic X-14547A (Indanomycin) (1984) (65)
- A microfluidic flow chemistry platform for organic synthesis: the Hofmann rearrangement (2009) (65)
- Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae (1990) (65)
- Synthesis of the thapsigargins. (2004) (65)
- Total synthesis of rapamycin. (2009) (65)
- The Diels–Alder route to drimane related sesquiterpenes; synthesis of cinnamolide, polygodial, isodrimeninol, drimenin and warburganal (1983) (65)
- A new asymmetric organocatalytic nitrocyclopropanation reaction. (2006) (64)
- Expedient preparation of nazlinine and a small library of indole alkaloids using flow electrochemistry as an enabling technology. (2014) (64)
- Trapping of palindromic ligands within native transthyretin prevents amyloid formation (2010) (64)
- Insect antifeedants: a behavioural and electrophysiological investigation of natural and synthetically derived clerodane diterpenoids (1988) (64)
- Multi-step application of immobilized reagents and scavengers: a total synthesis of epothilone C. (2004) (64)
- Cancer, chemistry, and the cell: molecules that interact with the neurotensin receptors. (2009) (64)
- Substitution reactions of 2-phenylsulphonyl-piperidines and -pyrrolidines with carbon nucleophiles: Synthesis of the pyrrolidine alkaloids norruspoline and ruspolinone (1991) (63)
- Magnesium nitride as a convenient source of ammonia: preparation of primary amides. (2008) (63)
- Organische Synthese: Vormarsch der Maschinen (2015) (62)
- Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry (2018) (62)
- Piperazic acid-containing natural products: isolation, biological relevance and total synthesis. (2011) (62)
- Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates. (2009) (62)
- Microbial oxidation in synthesis: preparation of (+)- and (−)-pinitol from benzene (1989) (62)
- Camera-enabled techniques for organic synthesis (2013) (62)
- Solid-supported reagents for multi-step organic synthesis: preparation and application. (2002) (61)
- Cyclohexane‐1,2‐diacetals (CDA): A New Protecting Group for Vicinal Diols in Carbohydrates (1994) (59)
- Total synthesis of spongistatin 1: a synthetic strategy exploiting its latent pseudo-symmetry. (2005) (58)
- Total synthesis of thapsigargin, a potent SERCA pump inhibitor. (2007) (57)
- A General Continuous Flow Method for Palladium Catalysed Carbonylation Reactions Using Single and Multiple Tube‐in‐Tube Gas‐Liquid Microreactors (2014) (56)
- Scaling Up of Continuous Flow Processes with Gases Using a Tube-in-Tube Reactor: Inline Titrations and Fanetizole Synthesis with Ammonia (2013) (56)
- Cyclopropanation using flow-generated diazo compounds. (2015) (56)
- A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1. (2013) (56)
- Process Intensification for the Continuous Flow Hydrogenation of Ethyl Nicotinate (2014) (55)
- Clean five-step synthesis of an array of 1,2,3,4-tetra-substituted pyrroles using polymer-supported reagents (1999) (55)
- A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid (2012) (55)
- The structure of two new clerodane diterpenoid potent insect antifeedants from Scutellaria woronowii (Juz); jodrellin A & B (1989) (55)
- Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide (2014) (54)
- Total synthesis of the insect antifeedant ajugarin I and degradation studies of related clerodane diterpenes (1986) (54)
- Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines (2017) (54)
- Preparation of spiroketals by reaction of anions from 2-benzenesulphonyltetrahydropyrans with epoxides: synthesis of the c-11 to c-25 fragment of the milbemycins☆ (1986) (53)
- Engineering chemistry for the future of chemical synthesis (2017) (53)
- A concise total synthesis of (+)-okaramine C. (2004) (53)
- A prototype device for evaporation in batch and flow chemical processes (2013) (52)
- Preparation of acyltetronic acids using t-butyl acetothioacetate: total synthesis of the fungal metabolites carolic, carlosic, and carlic acids (1987) (52)
- Continuous flow chemistry: a discovery tool for new chemical reactivity patterns. (2014) (52)
- Activity of drimane antifeedants and related compounds against aphids, and comparative biological effects and chemical reactivity of (−)- and (+)-polygodial (1988) (51)
- Solid Phase Synthesis of Bicyclo[2.2.2]octane Derivatives via Tandem Michael Addition Reactions and Subsequent Reductive Amination (1995) (51)
- Across‐the‐World Automated Optimization and Continuous‐Flow Synthesis of Pharmaceutical Agents Operating Through a Cloud‐Based Server (2018) (51)
- Magnesium nitride as a convenient source of ammonia: preparation of dihydropyridines. (2008) (50)
- Microbial oxidation in synthesis: Preparation from benzene of the cellular secondary messenger myo-inositol-1,4,5-trisphosphate (IP3) and related derivatives (1988) (50)
- Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes (2013) (50)
- Preparation and reactions of 2-benzenesulphonyltetrahydropyran (1985) (50)
- Catalytic oxidation of thiocarbonyl compounds involving the use of 1,2-Dibrometatrachloroethane as a brominating reagent for diaryl teII species (1980) (50)
- Tetrapropylammonium Perruthenate, Pr4N+RuO4‐, TPAP: A Catalytic Oxidant for Organic Synthesis (1994) (50)
- A fascination with 1,2-diacetals. (2007) (50)
- Wittig and horner-wittig coupling reactions of 2-substituted cyclic ethers and their application to spiroketal synthesis (1985) (49)
- Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins* (2011) (49)
- Synthesis, structure revision, and absolute configuration of (+)-didemniserinolipid B, a serinol marine natural product from a tunicate Didemnum sp. (2002) (49)
- The effects of phytochemical pesticides on the growth of cultured invertebrate and vertebrate cells. (2002) (48)
- A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones. (2006) (48)
- Rapid assembly of oligosaccharides: 1,2-diacetal-mediated reactivity tuning in the coupling of glycosyl fluorides (2000) (47)
- Use of 2-phenylsulphonyl cyclic ethers in the preparation of tetrahydropyran and tetrahydrofuran acetals and in some glycosidation reactions. (1991) (47)
- A conformational study of bafilomycin A1 by x-ray crystallography and nmr techniques (1987) (47)
- Tuning the Reactivity of Glycosides: Efficient One-pot Oligosaccharide Synthesis1 (1995) (47)
- Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor. (2007) (46)
- A Continuous Flow Solution to Achieving Efficient Aerobic Anti-Markovnikov Wacker Oxidation (2013) (46)
- The total synthesis of agglomerin A and (±)-carolinic acid. A general method for the preparation of 3-acyl tetronic acids via direct acylation of O-methyl 3-stannyl tetronates (1991) (46)
- Total synthesis of the protein phosphatase inhibitor okadaic acid (1998) (46)
- A relay route for the synthesis of azadirachtin. (2007) (45)
- Synthesis of the Nonamannan Residue of a Glycoprotein with High Mannose Content (1996) (45)
- Insect antifeedants from azadirachta indica (part 5): Chemical modification and structure-activity relationships of azadirachtin and some related limonoids (1989) (45)
- The use of β-ketothioesters for the exceptionally mild preparation of β-ketoamides (1987) (45)
- Preparation of 2-substituted pyrroles and indoles by regioselective alkylation and deprotection of 1-(2-trimethylsilylethoxymethyl)pyrrole and 1-(2-trimethylsilylethoxymethyl) indole (1986) (45)
- A "catch-react-release" method for the flow synthesis of 2-aminopyrimidines and preparation of the Imatinib base. (2012) (45)
- Diastereoselective chain-elongation reactions using microreactors for applications in complex molecule assembly. (2011) (44)
- Development of a polymer bound Wittig reaction and use in multi-step organic synthesis for the overall conversion of alcohols to β-hydroxyamines (1998) (44)
- A short stereoselective total synthesis of the fusarium toxin equisetin. (2000) (44)
- Development of beta-keto 1,3-dithianes as versatile intermediates for organic synthesis. (2003) (44)
- Pd‐EnCatTM TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl‐ and Alkenyl‐Substituted Acetylenes via Microwave‐Assisted Sonogashira Type Reactions (2009) (44)
- Pharmaceutical Strategy and Innovation: An Academics Perspective (2007) (43)
- Total synthesis of chloptosin. (2010) (43)
- The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib. (2013) (43)
- Design and Application of a Low-Temperature Continuous Flow Chemistry Platform (2014) (43)
- A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo[2,3-b]indole skeleton, a building block for 10b-hydroxy-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-diones. (2003) (43)
- Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues. (2011) (43)
- Diastereoselective oxygen to carbon rearrangements of anomerically linked enol ethers and the total synthesis of (+)-(S,S)-(cis-6-methyltetrahydropyran-2-yl)acetic acid, a component of civet (2000) (42)
- Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439. (2015) (42)
- Total synthesis of potent antifungal marine bisoxazole natural products bengazoles A and B. (2007) (42)
- Fully automated flow-through synthesis of secondary sulfonamides in a binary reactor system. (2007) (42)
- Clean and efficient synthesis of azo dyes using polymer-supported reagents (2000) (41)
- Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives. (2007) (41)
- Direct substitution of 2-benzenesulphonyl cyclic ethers using organozinc reagents (1988) (41)
- The use of π-allyltricarbonyliron lactone complexes in the synthesis of the β-lactone esterase inhibitor (−)-valilactone. (1991) (41)
- Synthesis of high-mannose type neoglycolipids: active targeting of liposomes to macrophages in gene therapy. (2000) (41)
- A facile route to imidazol-4-yl anions and their reaction with carbonyl compounds (1991) (41)
- An efficient and transition metal free protocol for the transfer hydrogenation of ketones as a continuous flow process (2009) (41)
- The synthesis of azadirachtin: a potent insect antifeedant. (2008) (41)
- The crystal structure of 3-epicaryoptin and the reversal of the currently accepted absolute configuration of clerodin (1979) (41)
- The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. (2005) (41)
- Research data supporting “Engineering Chemistry: Integrating batch and flow reactions on a single, automated reactor platform” (2016) (41)
- Total synthesis of the Fusarium toxin equisetin. (2005) (41)
- Organic Chemistry in Ionic Liquids Using Non-Thermal Energy-Transfer Processes (2005) (40)
- A total synthesis of epothilones using solid-supported reagents and scavengers. (2003) (40)
- A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl–Alkyl Cross‐Coupling Reactions (2017) (40)
- Total synthesis of the cyclic heptapeptide Argyrin B: a new potent inhibitor of T-cell independent antibody formation. (2002) (40)
- Preparation of cyclic ether acetals from 2-benzenesulphonylderivatives: a new mild glycosidation procedure (1988) (40)
- Solid-phase reaction monitoring--chemical derivatization and off-bead analysis. (2000) (40)
- One-pot Synthesis of Penta- and Hepta-saccharides from Monomeric Mannose Building Blocks Using the Principles of Orthogonality and Reactivity Tuning (1997) (40)
- A Palladium Wall Coated Microcapillary Reactor for Use in Continuous Flow Transfer Hydrogenation (2010) (40)
- A sequential tetra-n-propylammonium perruthenate (TPAP)–Wittig oxidation olefination protocol (2003) (40)
- A polymer-supported [1,3,2]oxazaphospholidine for the conversion of isothiocyanates to isocyanides and their subsequent use in an ugi reaction. (2002) (40)
- The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors. (2010) (39)
- Addition of dithiols to bis-ynones: development of a versatile platform for the synthesis of polyketide natural products. (2003) (39)
- Tricarbonyliron complexes: an approach to acyclic stereocontrol (1999) (39)
- A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor. (2008) (39)
- Dispiroketals in synthesis (part 2): A new group for the selective protection of diequatorial vicinal diols in carbohydrates. (1992) (39)
- Total synthesis of antascomicin B. (2005) (39)
- Butane-2,3-diacetals of glyceraldehyde: a stable alternative to glyceraldehyde acetonide. (2002) (38)
- Total synthesis of rapamycin. (2007) (38)
- Total synthesis of the polyenoyltetramic acid mycotoxin erythroskyrine (1999) (38)
- Selective acylation and alkylation reactions of diols using dibutyltin dimethoxide (1993) (38)
- Behavioural and neurophysiological responses of Spodoptera littoralis to azadirachtin and a range of synthetic analogues (1995) (38)
- The synthesis of the anti-malarial natural product polysphorin and analogues using polymer-supported reagents and scavengers. (2003) (38)
- Eintopfsynthese einer Trisaccharideinheit des gemeinen Polysaccharid-Antigens von Streptococci der Gruppe B unter Verwendung Cyclohexan-1,2-diacetal(CDA)-geschützter Rhamnoside† (1994) (37)
- Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents. (1999) (37)
- A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane‐1,2‐diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide (2006) (37)
- A Concise Synthesis of the Natural Product Carpanone Using Solid-Supported Reagents and Scavengers (2001) (37)
- A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles. (2012) (37)
- Flow Microwave Technology and Microreactors in Synthesis (2013) (37)
- Microbial oxidation in synthesis: Preparation of 6-deoxy cyclitol analogues of myo-inositol 1,4,5-trisphosphate from benzene (1989) (37)
- One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N-Tosylhydrazones: Access to 1,2,4-Triazines. (2017) (37)
- Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor. (2014) (36)
- Direct Protection of 1,2-Diols from α-Diketones (1996) (36)
- Synthesis of enantiomerically enriched 3-amino-2-oxindoles through a palladium-mediated asymmetric intramolecular arylation of α-ketimino amides. (2012) (36)
- Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods. (2011) (36)
- Conversion of thiocarbonyl compounds into their corresponding oxo derivatives using benzeneseleninic anhydride (1978) (36)
- Total synthesis of chloptosin: a dimeric cyclohexapeptide. (2011) (36)
- Highly diastereoselective lithium enolate aldol reactions of butane-2,3-diacetal desymmetrized glycolic acid and deprotection to enantiopure anti-2,3-dihydroxy esters. (2001) (36)
- Preparation of t-butyl 4-diethylphosphono-3-oxobutanethioate and use in the synthesis of (E)-4-alkenyl-3-oxoesters and macrolides (1987) (35)
- Regeneration of ketones from hydrazones, oximes, and semicarbazones by benzeneseleninic anhydride (1977) (35)
- Clean six-step synthesis of a piperidino-thiomorpholine library using polymer-supported reagents (1998) (35)
- A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines. (2007) (35)
- Enabling synthesis in fragment-based drug discovery by reactivity mapping: photoredox-mediated cross-dehydrogenative heteroarylation of cyclic amines† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04789h (2018) (35)
- Studies Towards the Synthesis of the C29-C51 Fragment of Altohyrtin A (1998) (35)
- A polymer-supported iridium catalyst for the stereoselective isomerisation of double bonds (2002) (35)
- A practical and efficient synthesis of the C-16-C-28 spiroketal fragment (CD) of the spongistatins. (2003) (35)
- Continuous flow based catch and release protocol for the synthesis of α-ketoesters (2009) (35)
- Chiral Glycolate Equivalents for the Asymmetric Synthesis of α-Hydroxycarbonyl Compounds (2007) (35)
- Synthesis of the Alkaloid Natural Products (+)-Plicane and (-)-Obliquine, Using Polymer-Supported Reagents and Scavengers (2005) (35)
- Butane-2,3-Diacetal-Desymmetrized Glycolic Acid-A New Building Block for the Stereoselective Synthesis of Enantiopure α-Hydroxy Acids. (2001) (35)
- Continuous Processing and Efficient in Situ Reaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy (2016) (35)
- SYNTHESIS OF METHYL‐1,6‐DIOXASPIRO(4,5)DECANES USING ORGANOSELENIUM‐MEDIATED CYCLIZATION REACTIONS (1982) (35)
- AuCl3‐Catalyzed Hydroalkoxylation of Conjugated Alkynoates: Synthesis of Five‐ and Six‐Membered Cyclic Acetals (2009) (34)
- Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography (2014) (34)
- Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to alpha-hydroxyacid and amide derivatives. (2004) (34)
- Optimisation of Conditions for O‐Benzyl and N‐Benzyloxycarbonyl Protecting Group Removal using an Automated Flow Hydrogenator (2007) (34)
- Use of polymer supported reagents for clean multi-step organic synthesis: preparation of amines and amine derivatives from alcohols for use in compound library generation (1998) (34)
- A New Phase-Switch Method for Application in Organic Synthesis Programs Employing Immobilization through Metal-Chelated Tagging We gratefully acknowledge financial support from Pfizer Global Research and Development, the University of Ferrara (Italy, Postdoctoral Fellowship to A.M.), the EU (Marie C (2001) (34)
- Preparation, structure, derivatisation and NMR data ofcyclohexane-1,2-diacetal protected carbohydrates (1997) (34)
- Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex (2016) (34)
- Real-Time Spectroscopic Analysis Enabling Quantitative and Safe Consumption of Fluoroform during Nucleophilic Trifluoromethylation in Flow (2018) (34)
- Multiple Microcapillary Reactor for Organic Synthesis (2010) (34)
- Directed syntheses of the isomeric dimethylcyclooctatetraenes and a study of their polarographic and alkali metal reduction (1974) (34)
- Sustainable flow Oppenauer oxidation of secondary benzylic alcohols with a heterogeneous zirconia catalyst. (2013) (33)
- Studies towards the total synthesis of rapamycin: A convergent and stereoselective synthesis of the C22C32 carbon framework (1994) (33)
- Total Synthesis of Avermectin B1a: Synthesis of the Carbohydrate Bis-Oleandrose Fragment and Coupling to the Avermectin B1a Aglycone (1990) (33)
- Combination of Enabling Technologies to Improve and Describe the Stereoselectivity of Wolff–Staudinger Cascade Reaction (2016) (33)
- A new route to spiro-ketals using the Horner-Wittig reaction of 2-diphenylphosphinoxy cyclic ethers (1984) (33)
- Selenium-mediated cyclization reactions of alkenyl-substituted β-ketoesters (1980) (33)
- The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors (2011) (33)
- Synthesis and use of a trifluoromethylated azomethine ylide precursor. (2012) (32)
- A practical catalytic method for the preparation of steroidal 1,4-dien-3-ones by oxygen atom transfer from iodoxybenzene to diphenyl diselenide (1982) (32)
- A convenient preparation of 2-haloenones from enones using phenylselenium halides (1982) (32)
- Natural‐Product‐Like Spiroketals and Fused Bicyclic Acetals as Potential Therapeutic Agents for B‐Cell Chronic Lymphocytic Leukaemia (2008) (32)
- Chemistry of insect antifeedants from Azadirachta indica(part 12): use of silicon as a control element in the synthesis of a highly functionalized decalin fragment of azadirachtin (1992) (32)
- Preparation of unsymmetrical ketones from tosylhydrazones and aromatic aldehydes via formyl C-H bond insertion. (2014) (32)
- Ultrasonic formation and reactions of sodium phenylselenide (1986) (32)
- Chemistry of insect antifeedants from azadirachta indica (part 4): synthesis towards the limonoid azadirachtin; preparation of a functionalised decalin fragment (1989) (31)
- Regioselective preparation of saturated spirocyclic and ring-expanded fused pyrazoles. (2014) (31)
- Synthesis of highly substituted nitropyrrolidines, nitropyrrolizines and nitropyrroles via multicomponent-multistep sequences within a flow reactor (2010) (31)
- Chemistry of insect antifeedants from azadirachta indica (part 8): Synthesis of hydroxydihydrofuran acetal fragments for biological evaluation and azadirachtin total synthesis studies. (1991) (31)
- Immobilization of thallium by tandem oxidation/reduction-complexation of thallium(I/III) (1992) (31)
- Total Syntheses of Linear Polythiazole/Oxazole Plantazolicin A and Its Biosynthetic Precursor Plantazolicin B** (2014) (30)
- Dynamic flow synthesis of porous organic cages. (2015) (30)
- Assessment of butene-1,4-diols as starting materials for the preparation of π-allyltricarbonyliron complexes (1990) (30)
- Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines (2011) (30)
- Preparation of the neolignan natural product grossamide by a continuous-flow process (2006) (30)
- The simultaneous use of immobilised reagents for the one-pot conversion of alcohols to carboxylic acids (2002) (30)
- Reconfiguration of a Continuous Flow Platform for Extended Operation: Application to a Cryogenic Fluorine-Directed ortho-Lithiation Reaction (2014) (30)
- Oxidation of alcohols using benzeneseleninic anhydride (1979) (30)
- Solid supported reagents in multi-step flow synthesis. (2006) (30)
- New cyclization procedure for alkenyl-substituted β-dicarbonyl compounds using N-phenylselenophthalimide (1981) (30)
- Dispiroketals: a new functional group for organic synthesis (1996) (30)
- The total synthesis of (+)-aspicilin using 2,3-butane diacetal protected butane tetrols via a chiral memory protocol (2001) (29)
- Total synthesis of polycephalin C and determination of the absolute configurations at the 3",4" ring junction. (2002) (29)
- Tetra-N-propylammonium perruthenate: a case study in catalyst recovery and re-use involving tetraalkylammonium salts. (2001) (29)
- Organic synthesis in a changing world. (2002) (29)
- Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides. (2004) (29)
- Mechanism of the thermal decomposition of tetra-aryltellurium species (1980) (29)
- Chemistry of insect antifeedants from Azadirachta Indica (Part 19): 1A potential relay route for the synthesis of azadirachtin (1995) (29)
- Maschinengestützte organische Synthese (2015) (29)
- The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions. (2015) (28)
- Use of t-butyl 4-diethylphosphono-3-oxobutanethioate for tetramic acid synthesis: Total synthesis of the plasmodial pigment fuligorubin A (1988) (28)
- Consecutive Three‐ and Four‐Component Coupling Reactions with Anions Generated from a Butane Diacetal Desymmetrized Glycolic Acid Derivative (2001) (28)
- Cyclisation reactions of alkenyl β-ketoesters involving a novel phenylseleno group migration (1981) (28)
- Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry (2015) (28)
- Autoradiographic localization of [22,23-(3)H(2)] dihydroazadirachtin binding sites in desert locust testes and effects of Azadirachtin on sperm motility. (1996) (28)
- Total synthesis of the structurally unique ionophore antibiotic X–14547 A (1983) (28)
- Oxidation of Activated Halides to Aldehydes and Ketones by N-Methylmorpholine-N-oxide (2006) (28)
- Total Synthesis of the Carboxylic Acid Ionophore Antibiotic CP-61,405 (Routiennocin) (1992) (28)
- Dispiroketals in Synthesis: Preparation of a Stable, Sterically Demanding Glyceraldehyde Ketal and Diastereoselective Reactions with Simple Organometallic Reagents (1992) (28)
- New building blocks for efficient and highly diastereoselective polyol production—synthesis and utility of (R ′,R ′,S,S ) and (S′,S′,R,R)-2,3-butane diacetal protected butane tetrol derivatives (1999) (28)
- Synthesis of a Precursor to Sacubitril Using Enabling Technologies. (2015) (28)
- Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds. (2006) (28)
- Dispiroketals in synthesis (part 10): Further reactions of dispoke protected lactate and glycolate enolates (1994) (28)
- Peptide-Based Materials (2012) (28)
- Fe2(co)g in tetrahydrofuran or under sonochemical conditions as convenient practical routes to π-allyltricarbonyliron lactone complexes (1984) (28)
- Preparation of desymmetrised meso-tartrate derivatives—synthesis and utility of (R′,R′,R,S)-2,3-butane diacetal protected dimethyl tartrate (1999) (28)
- Clean synthesis of α-bromo ketones and their utilisation in the synthesis of 2-alkoxy-2,3-dihydro-2-aryl-1,4-benzodioxanes, 2-amino-4-aryl-1,3-thiazoles and piperidino-2-amino-1,3-thiazoles using polymer-supported reagents (1999) (28)
- Stereoselective synthesis of inositol phosphates (1990) (27)
- A phase-switch purification approach for the expedient removal of tagged reagents and scavengers following their application in organic synthesis. (2005) (27)
- Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst. (2008) (27)
- Synthesis and chemistry of the insect antifeedant azadirachtin (1994) (27)
- Chemistry of insect antifeedants from Azadirachta indica (Part 10): synthesis of a highly functionalised decalin fragment of azadirachtin. (1991) (27)
- Continuous-Flow Processing of Gaseous Ammonia Using a Teflon AF-2400 Tube-in-Tube Reactor: Synthesis of Thioureas and In-Line Titrations (2012) (27)
- Synthestic approaches to the teleocidin-related tumour promoters: a total synthesis of (±)-indolactam V (1986) (27)
- Luminescence dynamics and carbon-13 NMR characteristics of dinuclear complexes exhibiting coupled lanthanide(III) cation pairs (1992) (27)
- Convergent total syntheses of callipeltosides A, B, and C. (2012) (26)
- Synthesis of the alkaloids (−)-heliotridane and (−)-isoretronecanol via π-allyltricarbonyliron lactam complexes. (1991) (26)
- Oxidation of ketone and aldehyde hydrazones, oximes, and semicarbazones and of hydroxylamines and hydrazo-compounds, using benzeneseleninic anhydride (1980) (26)
- Hydrogenation of aromatic ketones, aldehydes, and epoxides with hydrogen and Pd(0)EnCat™ 30NP (2006) (26)
- Total Synthesis of the Cyclic Peptide Argyrin B (2002) (26)
- Effect of azadirachtin-derived decalin (perhydronaphthalene) and dihydrofuranacetal (furo[2, 3-fo]pyran) fragments on the feeding behaviour of Spodoptera littoralis (1994) (26)
- Synthesis of the acyltetronic acid ionophore tetronasin (ICI M139603) (1998) (26)
- Bis(p-methoxyphenyl) telluroxide: a new, mild oxidising agent (1979) (26)
- Dispiroketals in synthesis (part 6): Highly stereoselective alkylation of dispiroketal protected lactate and glycolate enolates☆ (1994) (26)
- Dispiroketals in synthesis (part 4): Enantioselective desymmetrization of glycerol using a c2-symmetric disubstituted bis-dihydropyran. (1993) (26)
- A conformational study of elaiophylin by X-ray crystallography and difference 1H NMR methods; observation of a selective sign reversal of the nuclear overhauser effect (1982) (26)
- Stereocontrolled total synthesis of bengazole a: a marine bisoxazole natural product displaying potent antifungal properties. (2006) (26)
- Oxidation of phenols, pyrocatechols, and hydroquinones to ortho-quinones using benzeneseleninic anhydride (1981) (26)
- Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow. (2018) (26)
- Flow Chemistry: Intelligent Processing of Gas-Liquid Transformations Using a Tube-in-Tube Reactor (2015) (26)
- Clean three-step synthesis of 4,5-dihydro-1H-pyrazoles starting from alcohols using polymer supported reagents (1998) (26)
- Synthesis of Glycans from the Glycodelins: Two Undeca-, Two Deca-, Three Nona-, an Octa- and a Heptasaccharide (1999) (25)
- Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin. (2005) (25)
- Synthesis of Riboflavines, Quinoxalinones and Benzodiazepines through Chemoselective Flow Based Hydrogenations (2014) (25)
- Synthesis of spiroacetals using organoselenium-mediated cyclisation reactions. X-Ray molecular structure of (2S,8R)-8-methyl-2-phenyl-1,7-dioxaspiro[5.5]undecan-4(R)-ol (1984) (25)
- Identification of a putative azadirachtin-binding complex from Drosophila Kc167 cells. (2007) (25)
- Generation of Reactive Ketenes under Flow Conditions through Zinc-Mediated Dehalogenation (2015) (25)
- Preparation of episulphides from alkenes via succinimide-N-sulphenyl chloride or phthalimide-N-sulphenyl chloride adducts (1979) (25)
- Formation of 4-aminopyrimidines via the trimerization of nitriles using focused microwave heating. (2005) (25)
- Total synthesis of iso- and bongkrekic acids: natural antibiotics displaying potent antiapoptotic properties. (2011) (25)
- Synthesis of the β-lactam antibiotic (+)- thienamycin via an intermediate π-allyltricarbonyliron lactone complex (1985) (25)
- A total synthesis of millingtonine A. (2012) (25)
- Rapid, selective and stable HaloTag- Lb ADH immobilization directly from crude cell extract for the continuous biocatalytic production of chiral alcohols and epoxides (2018) (25)
- A Clean Conversion of Aldehydes to Nitriles Using a Solid-Supported Hydrazine (2002) (25)
- Experiments on the synthesis of tetracycline. Part 15. Oxidation of phenols and ring A model phenols to o-hydroxy-dienones with benzeneseleninic anhydride. (1977) (24)
- The Continuous-Flow Synthesisof Styrenes Using Ethylene in a Palladium-Catalysed Heck Cross-CouplingReaction (2011) (24)
- Synthesis of the β-lactone esterase inhibitor valilactone using π-allyltricarbonyliron lactone complexes. (1991) (24)
- Lesser-Known Enabling Technologiesfor Organic Synthesis (2011) (24)
- A new route to functionalised π-allyltricarbonyliron lactam complexes from aziridines and their use in stereoselective synthesis and oxidative conversion to β-lactams (1998) (24)
- Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors. (2015) (24)
- Chemistry of insect antifeedants from azadirachta indica (part 3): reactions on the C-22,23 enol ether double bond of azadirachtin and conversion to 22,23-dihydro-23-β-methoxyazadirachtin. (1988) (24)
- An Orthogonal Biocatalytic Approach for the Safe Generation and Use of HCN in a Multistep Continuous Preparation of Chiral O-Acetylcyanohydrins (2015) (24)
- Total synthesis of the sesquiterpene (±)-hirsutene using an organoselenium-mediated cyclization reaction (1985) (24)
- Synthesis of substituted cis-decalins as potential insect antifeedants (1981) (24)
- Preparation of O-methyl 3-acyl tetronic acids by the direct acylation of stannyl tetronates (1989) (23)
- Dispiroketals in synthesis (part 8): Regioselective protection of D-glucopyranose substrates (1994) (23)
- A highly enantioselective total synthesis of (+)-goniodiol. (2006) (23)
- The Use of Diethylaminosulfur Trifluoride (DAST) for Fluorination in a Continuous-Flow Microreactor (2008) (23)
- The first crystal and molecular structure of lanthanide homodinuclear macrocyclic complexes showing metal–metal pair interactions (1989) (23)
- Antivascular and anticancer activity of dihalogenated A-ring analogues of combretastatin A-4 (2010) (23)
- Peterson olefination using phenylsulphonyltrimethylsilylmethane. A new preparation of vinylic sulphones (1983) (23)
- The Use of Butane Diacetals of Glycolic Acid as Precursors for the Synthesis of the Phytotoxic Calmodulin Inhibitor Herbarumin II (2003) (23)
- Highly diastereoselective Michael addition reactions of butane-2,3-diacetal desymmetrized glycolic acid. Preparation of α-hydroxy-γ-amino acid derivatives (2001) (23)
- Back Pressure Regulation of Slurry‐Forming Reactions in Continuous Flow (2015) (23)
- Synthesis of isoxazolidines using polymer supported perruthenate (PSP) (1998) (23)
- Callipeltosides A, B and C: Total Syntheses and Structural Confirmation (2015) (23)
- A Simple, One-Pot, Glycosidation Procedure via (1-Imidazolylcaronyl) Glycosides and Zinc Bromide (1990) (22)
- Synthesis of the northern hemisphere of the milbemycins using a new strategy for the formation of the C15 to C16 bond. (1985) (22)
- Synthesis of natural products from the Indian neem tree Azadirachta indica. (2008) (22)
- Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride (2015) (22)
- Syngas-Mediated C-CBond Formation in Flow: Selective Rhodium-Catalysed Hydroformylationof Styrenes (2011) (22)
- SOLID-SUPPORTED REAGENTS FOR THE OXIDATION OF ALDEHYDES TO CARBOXYLIC ACIDS (2001) (22)
- Structural reappraisal of the limonoid insect antifeedant azadirachtin (1985) (22)
- The total synthesis of the annonaceous acetogenin, muricatetrocin C. (2000) (22)
- Characterization of azadirachtin binding to Sf9 nuclei in vitro. (2001) (22)
- An Asymmetric Tandem Conjugative Addition-Intramolecular Cyclisation Process to Provide Functionalised 3,6-Dihydropyrans and 4,5-Epoxytetrahydropyrans (2010) (22)
- Dehydrogenation of steroidal and triterpenoid ketones using benzeneseleninic anhydride (1981) (21)
- Development of methods suitable for natural product synthesis: The azadirachtin story (2005) (21)
- A total synthesis of (+)-Goniodiol using an anomeric oxygen-to-carbon rearrangement (1998) (21)
- 1,5-Asymmetric induction of chirality: highly diastereoselective addition reactions of organoaluminium reagents into ketone groups in the side-chain of π-allyltricarbonyliron lactone complexes (1997) (21)
- (S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric organocatalysts of broad utility in organic synthesis (2007) (21)
- Total syntheses of subereamollines A and B. (2011) (21)
- Studies towards the total synthesis of rapamycin: Preparation of the C10C17 carbon unit (1994) (21)
- Preparation of Butane-1,2-diacetal-protected l-Glyceraldehyde from d-Mannitol (2003) (21)
- Chemistry of insect antifeedants from Azadirachta Indica (part 18): Demethylation and methylation of the C-8 position of the decalin portion of azadirachtin (1995) (21)
- Assembly of dendritic glycoclusters from monomeric mannose building blocks (1998) (21)
- TETRACYANOETHYLENE ADDITION TO IRON TRICARBONYL COMPLEXES OF SUBSTITUTED CYCLOOCTATETRAENES, REGIOSELECTIVITY CONSIDERATIONS DURING FORMATION OF THE 2,3,4,10-TETRAHAPTO ADDUCTS (1975) (21)
- Chemistry of insect antifeedants from Azadirachta indica (part 11): Characterisation and structure activity relationships of some novel rearranged azadirachtins. ☆ (1991) (21)
- Spiroketal glycomimetics: the synthesis of a conformationally restrained Sialyl Lewis X mimic (1995) (20)
- The total synthesis of the clerodane diterpene insect antifeedant ajugarin I (1983) (20)
- Synthesis of the beta 2 agonist (R)-salmeterol using a sequence of supported reagents and scavenging agents. (2002) (20)
- A new ruthenium(VI) oxidant: preparation, X-ray crystal structure, and properties of (Ph4P)[RuO2(OAc)Cl2] (1990) (20)
- Cyclohexan‐1,2‐diacetale (CDA): eine neue Schutzgruppe für vicinale Diole in Kohlenhydraten (1994) (20)
- Oxidation of phenols to ortho-quinones using diphenylseleninic anhydride (1977) (20)
- Chemistry of Insect Antifeedants from Azadirachta indica (Part 22): Functionalisation of the Decalin Fragment of Azadirachtin via a Claisen Rearrangement Reaction (1999) (20)
- Application of ReactArray Robotics and Design of Experiments Techniques in Optimisation of Supported Reagent Chemistry (2002) (20)
- Fully automated multi-step solution phase synthesis using polymer supported reagents: preparation of histone deacetylase inhibitors. (2003) (20)
- Synthetic studies towards the acyltetronic acid iohophore M 139603 (1986) (19)
- Total Synthesis of Avermectin B1a: Synthesis of the C11-C25 Spiroacetal Fragment (1990) (19)
- Dispiroketals in synthesis (part 19)1: Dispiroketals as enantioselective and regioselective protective agents for symmetric cyclic and acyclic polyols. (1995) (19)
- Chemistry of insect antifeedants from (part 1): Conversion from the azadirachtin to the azadirachtinin skeletons (1988) (19)
- Dehydrogenation of steroidal ketones using benzeneseleninic anhydride (1978) (19)
- “Connectivist” approach to organic structure determination Lsd-program assisted Nmr analysis of the insect antifeedant Azadirachtin (1994) (19)
- Uptake, retention, metabolism and excretion of [22,23-3H2]dihydroazadirachtin in Schistocerca gregaria (1993) (19)
- Chemistry of insect antifeedants from azadirachta indica (Part 9): oxidative reactions of azadirachtin derivatives leading to C8-C14 bond cleavage. (1991) (19)
- A New Methodology for Incorporating Chiral Linkers into Stapled Peptides (2017) (19)
- A general and efficient procedure for the preparation of enantiopure anti-1,2-diols—synthesis and utility of (R′,R′,S,R)-2,3-butane diacetal protected butane tetrol (1999) (19)
- Microwave Promoted Hydrolysis of Esters Absorbed on Alumina: A New Deprotection Method for Pivaloyl Groups (1993) (19)
- Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives. (2005) (19)
- Synthesis of (-)-gloeosporone, a fungal autoinhibitor of spore germination using a pi-allyltricarbonyliron lactone complex as a templating architecture for 1,7-diol construction. (2003) (19)
- Synthesis of a C16–C28 spiroacetal fragment of avermectin B1a and reassignment of some 1H and 13C resonances of avermectin B1a (1990) (19)
- Synthesis of trifluoromethyl ketones using polymer-supported reagents. (2002) (18)
- The X-ray structure and absolute configuration of insect antifeedant clerodane diterpenoids from Teucrium africanum (1982) (18)
- Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1. (2012) (18)
- Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin. (2007) (18)
- Regiospecific alkylation of β-ketothioesters and use in the synthesis of acyl-tetronic acids (1983) (18)
- Dispiroketals in Synthesis (Part 3):1Selective Protection of Diequatorial Vicinal Diols in Carbohydrates (1993) (18)
- A mild, enantioselective synthesis of (R)-salmeterol via sodium borohydride–calcium chloride asymmetric reduction of a phenacyl phenylglycinol derivative (2002) (18)
- A practical method for continuous production of sp3-rich compounds from (hetero)aryl halides and redox-active esters. (2020) (18)
- Fast continuous alcohol amination employing a hydrogen borrowing protocol (2019) (18)
- Rapid access to rare natural pyranosides using 1,2-diacetal protected intermediates (1997) (18)
- Second-generation synthesis of azadirachtin: a concise preparation of the propargylic mesylate fragment. (2009) (17)
- Tricarbonyliron lactone complexes in organic synthesis (1994) (17)
- Diastereoselective addition reactions to carbonyl groups in the side-chain of π-allytricarbonyliron lactone complexes (1994) (17)
- Chemistry of insect antifeedants from azadirachta indica (part 6): Synthesis of an optically pure acetal intermediate for potential use in the synthesis of azadirachtin and novel antifeedants. (1990) (17)
- Grignard additions to 2-uloses: synthesis of stereochemically pure tertiary alcohols (2004) (17)
- Studies towards the total synthesis of rapamycin: Preparation of the cyclohexyl C33C42 fragment and further coupling to afford the C22C42 carbon unit (1994) (17)
- Chemistry of insect antifeedants from Azadirachta Indica (Part 15):1 Degradation studies of Azadirachtin leading to C8C14 bond cleavage. (1993) (17)
- Preparation of lactones via tricarbonyliron–lactone complexes (1981) (17)
- Identification of Azadirachtin in Tissue-Cultured Cells of Neem (Azadirachta Indica) (1997) (17)
- Natural product synthesis using π-allyltricarbonyliron lactone complexes: Synthesis of parasorbic acid, the carpenter bee pheromone and malyngolide (1985) (17)
- Total syntheses of the bromotyrosine-derived natural products ianthelline, 5-bromoverongamine and JBIR-44 (2010) (17)
- Dispiroketals in synthesis. Part 24.1 Preparation and use of chiral 2,2′-bis(triisopropylsilyloxymethyl)bi(dihydropyran)s as new protecting and resolving agents for 1,2-diols (1999) (17)
- Application of ultrasound to the preparation of tricarbonyliron diene complexes (1986) (17)
- Chemical synthesis of the N-glycans of gp63, the major surface glycoprotein from Leishmania mexicana amazonensis (1999) (16)
- Chemistry of insect antifeedants from Azadirachta indica, Part 14: absolute configuration of azadirachtin (1992) (16)
- Oxygen atom transfer from iodylbenzene to diphenyl diselenide - a convenient method for dehydrogenation of steroidal 3-ketones (1981) (16)
- Organic synthesis with tricarbonyliron lactone complexes (1988) (16)
- Fully automated polymer-assisted synthesis of 1,5-biaryl pyrazoles. (2004) (16)
- Dispiroketals in synthesis (part 7): Protection of D-glucopyranose substrates☆ (1994) (16)
- Microbial Oxidation in Synthesis: Concise Preparation of (+)-Conduritol F from Benzene (1990) (16)
- Controlled generation and use of CO in flow (2016) (16)
- A short syntesis of (±)-hirsutene involving the use of an organoselenium-mediated cyclization reaction (1982) (16)
- Chemistry of insect antifeedants from (part 2): Synthesis of a polyoxygenated decalin with limonoid structural homology. (1988) (16)
- DIASTEREOSELECTIVE ANOMERIC OXYGEN TO CARBON REARRANGEMENTS OF SILYL ENOL ETHER DERIVATIVES OF LACTOLS (1998) (16)
- Synthesis of the C12–C26 fragment of the acyltetronic acid lonophore antibiotic tetronasin (ici 139603) (1990) (16)
- Synthesis of ?-lactams from ?-allyltricarbonyliron (lactone) complexes (1983) (16)
- Synthesis of trifluoromethylated isoxazoles and their elaboration through inter- and intra-molecular C-H arylation. (2016) (16)
- Highly regioselective lithiation of pyridines bearing an oxetane unit by n-butyllithium. (2014) (16)
- A Rapid Approach for the Optimisation of Polymer Supported Reagents in Synthesis (2000) (16)
- Substitution reactions of 2-benzenesulphonyl cyclic ethers with silyl enol ethers promoted by aluminium trichloride (1989) (16)
- Chemistry of insect antifeedants from azadirachta indica (part 7): Preparation of an optically pure hydroxyacetal epoxide related to azadirachtin. (1990) (16)
- Use of π-allyltricarbonyliron lactone complexes in the synthesis of taurospongin A: a potent inhibitor of DNA polymerase β and HIV reverse transcriptase (2003) (16)
- Novel polyene cyclisation routes to the acyl tetronic acid ionophore tetronasin (ICI M139603) (1994) (16)
- Two new routes to the C19C26 tetrahydrofuran fragment of the acyl tetronic acid ionophore tetronasin (ICI M139603) (1994) (16)
- Biosynthesis of tetronasin: Part 1 introduction and investigation of the diketide and triketide intermediates bound to the polyketide synthase (1994) (16)
- Synthesis, Chiroptical Properties, and Absolute Configuration of (+)-2,3-Dihydrotriquinacen-2-one. Effect of Rigid Triquinacene Geometry on the Inherently Dissymmetric Chromophore (1975) (15)
- Direct Substitution of 2-Benzenesulphonylpiperidines and -pyrrolidines by Carbon Nucleophiles: Synthesis of the Pyrrolidine Alkaloid Ruspolinone (1990) (15)
- Oxidation of aldehyde hydrazones, hydrazo compounds, and hydroxylamines with benzeneseleninic anhydride (1978) (15)
- Synthesis of cinnamolide and polygodial (1981) (15)
- TPAP: Tetra-n-propylammonium Perruthenate, a Mild and Convenient Oxidant for Alcohols (1990) (15)
- Scale-Up of Flow-Assisted Synthesisof C2-Symmetric Chiral PyBoxLigands (2012) (15)
- Synthesis of antifeedants for insects: novel behaviour-modifying chemicals from plants. (1990) (15)
- A total synthesis of the ammonium ionophore, (−)-enniatin B (2012) (15)
- Synthetic studies towards the clerodane insect antifeedant jodrellin A: preparation of a polycyclic model compound with antifeedant activity (1996) (15)
- 1,5-Asymmetric induction of chirality: highly diastereoselective synthesis of homoallylic tertiary alcohols by the Lewis acid-mediated addition of allylstannanes into ketones in the side-chain of π-allyltricarbonyliron lactone complexes (1997) (15)
- Chemoselective Continuous Ru-Catalyzed Hydrogen-Transfer Oppenauer-Type Oxidation of Secondary Alcohols (2017) (15)
- Removal of thioacetal protecting groups by benzeneseleninic anhydride (1980) (15)
- Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3-Bromoisoxazolines (2017) (15)
- Oxygen to carbon rearrangements of anomerically linked alkenols from tetrahydropyran derivatives: an investigation of the reaction mechanism via a double isotopic labelling crossover study (2000) (15)
- Preparation of vinylic sulphones by Peterson olefination using phenyl trimethylsilylmethyl sulphone (1985) (15)
- Anomeric oxygen to carbon rearrangements of alkynyl tributylstannane derivatives of furanyl (γ)- and pyranyl (δ)-lactols (2004) (15)
- Preparation of β-ketomacrolactones and β-ketodiolides using S-t-butyl 3-oxobutanethioate and S-t-butyl 4-diethylphosphono-3-oxobutanethioate (1989) (15)
- Continuous stream processing: a prototype magnetic field induced flow mixer (2012) (15)
- The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of α-amino acids and α,α-disubstituted amino acids (2004) (15)
- Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes (2017) (15)
- The Evolution of Immobilized Reagents and Their Application in Flow Chemistry for the Synthesis of Natural Products and Pharmaceutical Compounds (2012) (15)
- Analytical techniques for small molecule solid phase synthesis. (2002) (15)
- Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers (2002) (15)
- Direct Substitution of 2-Phenylsulphonylpyrrolidines, -piperidines, -tetrahydrofurans and -tetrahydropyrans by Alkyl Organometallic Reagents in Dichloromethane (1990) (15)
- Total Synthesis of Avermectin B1a: Final Coupling Reactions and the Total Synthesis of Avermectin B1a Aglycone (1990) (15)
- A convenient route to enantiomerically pure 2-substituted methyl glycerate derivatives. (2003) (14)
- Analytical construct resins for analysis of solid-phase chemistry. (2002) (14)
- Integrated plug flow synthesis and crystallisation of pyrazinamide (2018) (14)
- Synthesis of (±)warburganal (1981) (14)
- Synthesis of the spiroacetal unit related to the avermectins and milbemycins (1985) (14)
- Polymer supported reagents in synthesis: preparation of bicyclo[2.2.2] octane derivates via Tandem Michael addition reactions and subsequent combinatorial decoration. (2000) (14)
- Parallel solution-phase syntheses of functionalised bicyclo[2.2.2]octanes: generation of a library using orchestrated multi-step sequences of polymer-supported reagents and sequesterants (2000) (14)
- A New Route to Butane-1,2-diacetals and the Development of Alternative Substitution Patterns to Facilitate Differential Protection of the Products (2001) (14)
- Total Synthesis of Avermectin B1a: Planning of the Synthesis and Preparation of the C1-C10 "Southern" Hydrobenzofuran Fragment (1990) (14)
- Unveiling the role of boroxines in metal-free carbon–carbon homologations using diazo compounds and boronic acids† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02264f, additional data is available from the University of Cambridge Data Repository Website: https://doi.or (2017) (14)
- Flow‐Based, Cerium Oxide Enhanced, Low‐Level Palladium Sonogashira and Heck Coupling Reactions by Perovskite Catalysts (2014) (14)
- Synthesis of 3-Nitropyrrolidinesvia Dipolar Cycloaddition Reactions Using a Modular Flow Reactor (2010) (14)
- Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release. (2013) (14)
- Total synthesis of (+)-milbemycin β1 (1989) (14)
- Development of a flow method for the hydroboration/oxidation of olefins. (2015) (14)
- Efficient synthesis of (-)-triquinacene-2-carboxylic acid (1974) (14)
- Total synthesis of the polyenoyltetramic acid polycephalin C (2003) (14)
- Synthesis of (cis-6-methyltetrahydropyran-2-yl)acetic acid involving the use of an organoselenium-mediated cyclization reaction (1983) (14)
- Three-Component Assembly of Multiply Substituted Homoallylic Alcohols and Amines Using a Flow Chemistry Photoreactor. (2018) (14)
- The synthesis and assay of radiolabelled benzene derivatives (1995) (14)
- The Internet of Chemical Things (2015) (14)
- Synthesis of the monocyclic nonaromatic C-1 to C-10 fragments of the milbemycins and avermectins. (1987) (14)
- The synthesis of neurotensin antagonist SR 48692 for prostate cancer research. (2013) (13)
- Integrating Microwave‐Assisted Synthesis and Solid‐Supported Reagents (2009) (13)
- A Photoredox Coupling Reaction of Benzylboronic Esters and Carbonyl Compounds in Batch and Flow. (2019) (13)
- Magnesium Nitride as a ConvenientSource of Ammonia: Preparation of Pyrroles (2008) (13)
- The synthesis of trisubstituted tetrahydrofurans via the use of an organoselenium-mediated cyclisation reaction (1986) (13)
- Dispiroketals in Synthesis (Part 20)1: Preparation of Chiral 2,2’-Bis(halomethyl) and 2,2’-Bis(phenylthiomethyl)dihydropyrans (1996) (13)
- Oxidation Reactions in Segmented and Continuous Flow Chemical Processing Using an N-(tert-Butyl)phenylsulfinimidoyl Chloride Monolith (2011) (13)
- An Integrated Flow and Batch-BasedApproach for the Synthesis of O-Methyl Siphonazole (2011) (13)
- Protecting Groups: Effects on Reactivity, Glycosylation Stereoselectivity, and Coupling Efficiency (2008) (13)
- Visible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives. (2017) (13)
- Dispiroketals in synthesis. Part 25.1 Further reactions of dispiroketal protected glycolate to afford optically active 1,2,3,4-tetraols (1999) (13)
- Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification (2016) (13)
- Total synthesis of the cholesterol biosynthesis inhibitor 1233A via a (π-allyl)tricarbonyliron lactone complex (1999) (13)
- Microbial Oxidation in Synthesis: Preparation of a Potential Insulin Mimic from Benzene (1992) (13)
- Photochemical Homologation for the Preparation of Aliphatic Aldehydes in Flow. (2018) (13)
- The Engineering of Chemical Synthesis: Humans and Machines Working in Harmony. (2018) (13)
- Modern synthetic methods for copper-mediated C(aryl)[bond]O, C(aryl)[bond]N, and C(aryl)[bond]S bond formation. (2004) (13)
- Biosynthesis of tetronasin: Part 2 identification of the tetraketide intermediate attached to the polyketide synthase (1994) (13)
- Mećhanistic dichotomy in cycloadditions to cyclooctatetraeneiron tricarbonyl. X-ray crystal structure analysis of the TCNE and CSI adducts (1973) (13)
- Microbial oxidation in synthesis : preparation of pseudo-α-D-glucopyranose from benzene (1992) (13)
- Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods (2013) (13)
- Alkali metal reduction studies of cis- and trans-bicyclo[6.1.0]nona-2,4,6-trienes in liquid ammonia. Evidence for the high basicity of monohomocyclooctatetraene dianions (1974) (13)
- 1,7-Induction of chirality in Mukaiyama aldol reactions using π-allyltricarbonyliron lactone and lactam complexes as chiral templates (1999) (13)
- Dispiroketals in synthesis (Part 13): Functionalised dispiroketals as new chiral auxiliaries; highly stereoselective diels-alder reactions using a bifunctional, C2- symmetrical chiral auxiliary (1994) (13)
- A 2,3-butanedione protected chiral glycine equivalent--a new building block for the stereoselective synthesis of enantiopure N-protected alpha-amino acids. (2003) (13)
- 1,5-Asymmetric induction of chirality: diastereoselective addition of organoaluminium reagents and allylstannanes into aldehyde groups in the side-chain of π-allyltricarbonyliron lactone complexes (1997) (13)
- The question of delocalization in "anchored" ions with potential trishomoaromatic character. 1. Reduction of tricyclo[5.4.1.04,12]dodeca-2,5,8,10-tetraene as a route to the 10.pi.11C dianion (1977) (12)
- Synthesis of 4-Substituted Imidazoles via 4-Metallo Imidazole Intermediates (1993) (12)
- Fluorous Chemistry (2012) (12)
- Microbial Oxidation in Synthesis: A Six Step Preparation of (.+-.)-Pinitol from Benzene. (1987) (12)
- A Flow Process Using Microreactorsfor the Preparation of a Quinolone Derivative as a Potent5HT1B Antagonist (2010) (12)
- Copper- and Palladium-Containing Perovskites: Catalysts for the Ullmann and Sonogashira Reactions (2005) (12)
- Dispiroketals in synthesis (Part 11): Concomitant enantioselective and regioselective protection of 2,5- dibenzoyl-myo-inositol (1994) (12)
- Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin (2013) (12)
- Polymer-assisted, multi-step solution phase synthesis and biological screening of histone deacetylase inhibitors. (2004) (12)
- Biosynthesis of tetronasin: Part 3 preparation of deuterium labelled tri- and tetraketides as putative biosynthetic precursors of tetronasin (1994) (12)
- A Comment on Continuous Flow Technologies within the Agrochemical Industry (2021) (12)
- Chemoenzymatic synthesis of L-galactosylated dimeric sialyl Lewis X structures employing alpha-1,3-fucosyltransferase V. (2000) (12)
- Alkenylcyclic Sulphites as Novel Precursors for the Preparation of π-Allyltricarbonyliron Lactone Complexes (1990) (12)
- Preparation of aldehydes and ketones by oxidation of benzylic hydrocarbons with benzeneseleninic anhydride (1979) (12)
- A new synthesis of (−)-epipyriculol: a phytotoxic metabolite (2008) (11)
- KMnO4-Mediated Oxidation as a Continuous Flow Process. (2010) (11)
- Dispiroketals in synthesis (Part 17): Regioselective protection of D-glucopyranoside D-galactopyranoside and D-mannopyranoside substrates. (1994) (11)
- NEW POLYETHYLENE GLYCOL POLYMERS AS KETAL PROTECTING GROUPS – A POLYMER SUPPORTED APPROACH TO SYMMETRICALLY SUBSTITUTED SPIROKETALS (2001) (11)
- Dispiroketals in synthesis. Part 23.1 A newroute to (+)-D-conduritol B frommyo-inositol (1997) (11)
- Model studies towards the insect antifeedant Jodrellin A using an organoselenium mediated cyclization reaction (1994) (11)
- 5-Pyrrolidin-2-yltetrazole: A new, catalytic, more soluble alternative to proline in an organocatalytic asymmetric Mannich-type reaction (2004) (11)
- Thermal reactions of 1,4-bridged-1,2,3,4-tetrahydronaphthalene derivatives (1972) (11)
- Photoredox Generation of Sulfonyl Radicals and Coupling with Electron Deficient Olefins. (2020) (11)
- Chemistry of insect antifeedants from Azadirachta indica (Part 17): Synthesis of model compounds of azadirachtin. Unusual effect of remote substituents on the course of the oxidative ring contraction reaction. (1994) (11)
- Use of the Potassium Ion as a Template for the Selective Derivatization of the Antibiotic X-206 (1999) (11)
- [3 + 2] Cycloaddition of Acetylenes with Azides to Give 1,4‐Disubstituted 1,2,3‐Triazoles in a Modular Flow Reactor. (2007) (11)
- Towards the synthesis of the C37-C42 fragment of rapamycin: intramolecular reactions of allyl silanes with oxonium ions generated from α-alkoxy sulfones. (1994) (11)
- Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow Processes (2013) (11)
- Synthesis of euryfuran, valdiviolide, and confertifolin (1982) (11)
- The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow (2013) (11)
- Effiziente Synthese von Oligosacchariden: Totalsynthese eines Glycosylphosphatidyl- inosit-Ankers aus Trypanosoma brucei (1998) (11)
- π-Allyltricarbonyliron lactone complexes in synthesis: application to the synthesis of the β-lactam antibiotic (+)-thienamycin (1984) (11)
- An intramolecular Diels-Alder approach to the synthesis of the right hand half of the ionophore antibiotic X-14547A (1981) (11)
- Development of a synthetic route towards milbemycin β1: Preparation of an advanced model system. (1987) (11)
- Aryne chemistry. Part XXXIV. Reactions of NN-dimethylarylamines with tetrahalogenobenzynes (1974) (11)
- Unsaturated heterocyclic systems. XCII. Nitrogen analogs of 1,6-methano[12]annulene. Effect on valence tautomerism of the locus of aza substitution (1975) (11)
- Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis. (2009) (11)
- Synthesis of β-dimorphecolic acid exploiting highly stereoselectivereduction of a side-chain carbonyl group in a π-allyltricarbonylironlactone complex (1997) (11)
- Chemistry of insect antifeedants from Azadirachta indica(part 21): synthesis of model compounds of azadirachtin using a decalin framework as a functional group scaffolding (1996) (11)
- Synthesis of polyoxygenated trans-decalins as potential insect antifeedants (1982) (11)
- Formation of monohomocyclooctatetraene dianions in liquid ammonia. Analysis of the nucleophilic reactivity of the cyclononatrienyl anions generated upon solvent protonation (1976) (10)
- Immobilisierung durch festphasengebundene Metalle als neuartige Phasenwechselmethode für die organische Synthese (2001) (10)
- Solid-phase development of a L-hydroxybenzotriazole linker for heterocycle synthesis using analytical constructs. (2001) (10)
- Preparation of phenylselenoimines from phenols using diphenylseleninic anhydride and hexamethyldisilazane (1977) (10)
- Flow synthesis of cyclobutanones via [2 + 2] cycloaddition of keteneiminium salts and ethylene gas (2017) (10)
- Studies of a Diastereoselective Electrophilic Fluorination Reaction Employing a Cryo-Flow Reactor (2013) (10)
- On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones (2016) (10)
- Continuous direct anodic flow oxidation of aromatic hydrocarbons to benzyl amides (2017) (10)
- Highly cis- or trans-selective oxygen to carbon rearrangements of anomerically linked 6-substituted tetrahydropyranyl enol ethers (1999) (10)
- 1,7-Asymmetric induction of chirality in a Mukaiyama aldol reaction using π-allyltricarbonyliron lactone complexes: highly diastereoselective synthesis of α-substituted β-hydroxy carbonyl compounds (2000) (10)
- C-H functionalisation of aldehydes using light generated, non-stabilised diazo compounds in flow. (2018) (10)
- Anomeric Oxygen to Carbon Rearrangements of Alkynyl Tributylstannane Derivatives of Lactols. (1998) (10)
- Enantioselective synthesis of the C3-C11 hydrocarbon fragment of the ionophore antibiotic tetronasin (ici 139603). (1990) (10)
- Total synthesis of the spiroketal macrolide (+) milbemycin α1 (1993) (10)
- Biosynthesis of tetronasin: Part 4, preparation of deuterium labelled C19-C26, C17-C26, C11-C26 and C3-C26 polyketide fragments as putative biosynthetic precursors of the ionophore antibiotic tetronasin (ICI 139603)☆ (1995) (10)
- Dispiroketals in synthesis (Part 12): Functionalised dispiroketals as new chiral auxiliaries; the synthesis of dihydroxylated dispiroketals in optically pure form☆ (1994) (10)
- An Efficient Three-Step Synthesis of L-(-)-Oleandrose from (S)-(-)-Methyl Lactate (1990) (10)
- Supported Reagents and Scavengers in Multi‐step Organic Synthesis (2005) (10)
- Iterative Reactions of Transient Boronic Acids Enable Sequential C—C Bond Formation. (2016) (10)
- A practical deca-gram scale ring expansion of (R)-(-)-carvone to (R)-(+)-3-methyl-6-isopropenyl-cyclohept-3-enone-1. (2015) (10)
- Removal of 1,3-dithiolan protecting groups by benzeneseleninic anhydride (1977) (10)
- Use of π-allyltricarbonyliron lactam complexes in the preparation of nocardicin derivatives: synthesis of (–)-3-oxo-1-[(p-benzyloxyphenyl)-benzyloxycarbonylmethyl]azetidin-2-one (1985) (10)
- Synthesis of the drimane-related sesquiterpenes euryfuran, confertifolin, and valdiviolide (1983) (10)
- A Short and Efficient Stereoselective Synthesis of the Potent 5-Lipoxygenase Inhibitor CMI-977 (2000) (9)
- Copper(I)‐Catalyzed Preparation of (E)‐3‐Iodoprop‐2‐enoic Acid (2003) (9)
- Formation of β-lactams from tricarbonyliron lactone complexes (1980) (9)
- One-Pot Synthesis of Tetra- and Pentasaccharides from Monomeric Building Blocks Using the Principles of Orthogonality and Reactivity Tuning. (2010) (9)
- Total Synthesis of the Carboxylic Acid lonophore Antibiotic CP-61,405 (Routiennocin): Preparation of the Inherent Spiroketal Unit via a Reverse Coupling Process (1992) (9)
- Behavioural responses of locusts and Spodoptera littoralis to azadirachtin and azadirachtin analogues containing fluorescent and immunogenic reporter groups (1995) (9)
- Double diastereodifferentiation in the Mukaiyama aldol reactions of π-allyltricarbonyliron lactone complexes: 1,7- vs. 1,2-asymmetric induction (1998) (9)
- Magnesium Nitride as a Convenient Source of Ammonia: Preparation of Pyrroles. (2009) (9)
- The stability of NN-dialkylthiohydroxylamines (1975) (9)
- Continuous Pd-Catalyzed Carbonylative Cyclization Using Iron Pentacarbonyl as a CO Source. (2019) (9)
- Mukaiyama aldol reactions of π-allyltricarbonyliron lactone and lactam complexes bearing trimethylsilyl enol ether side-chains. Not just formal, but genuine 1,7 induction of chirality (1998) (9)
- The clerodane ring system: investigating the viability of a direct Diels-Alder approach. (2011) (9)
- Dispiroketals in Synthesis (Part 22)1: Use of Chiral 2,2’-Bis(phenylthiomethyl)dihydropyrans as New Protecting and Resolving Agents for 1,2-Diols (1996) (9)
- Synthesis and chemistry of the ionophore antibiotic tetronasin. (1996) (9)
- Direct Oxidation of Csp3 -H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow. (2018) (9)
- Application of polymer-supported enzymes and reagents in the synthesis of γ-aminobutyric acid (GABA) analogues (2002) (9)
- Reductive decomplexation of pi-allyltricarbonyliron lactone complexes using sodium naphthalenide as a route to stereodefined 1,7-diols and 2,3-diene-1,7-diols. (2003) (9)
- Dispiroketals in Synthesis (Part 15): Simultaneous Enantioselective and Regioselective Protection of Glycerol by Reaction with C2 Symmetric (4S,4′S)-Dimethyl-bis-dihydropyran (1994) (9)
- Isolation, Characterisation and Oxidation of Isomeric Ferrelactone Complexes. (1979) (9)
- Fully Automated Sequence-Specific Synthesis of α-Peptides Using Flow Chemistry (2015) (9)
- Synthesis of spongistatin 2 employing a new route to the EF fragment (2013) (9)
- Synthesis of a novel 3, 4-dihydromilbemycin analogue. (1987) (9)
- Taming Hazardous Chemistry by Continuous Flow Technology (2016) (9)
- Thermal rearrangement reactions of tricarbonyliron lactone complexes (1982) (9)
- Research data supporting "A multicomponent approach for the preparation of homoallylic alcohols" (2016) (8)
- Functionalised butanediacetal-protected 1,2-diols as suitable partners for Pd-catalysed cross-coupling reactions (2008) (8)
- Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists. (2015) (8)
- Synthesis of Enantiomers of Butane-1,2-diacetal-Protected Glyceraldehyde and of (R,R)-Butane-1,2-diacetal-Protected Glycolic Acid (2003) (8)
- Diastereoselective addition reactions of allylstannanes to carbonyl groups in the side-chain of π-allyltricarbonyliron lactone complexes (1996) (8)
- Synthesis of carbohydrate derivatives using solid-phase work-up and scavenging techniques. (2003) (8)
- Click Triazoles (2012) (8)
- Dispiroketals in synthesis (part 9): Resolution of 1,2-diols using a C2-symmetric diphenyltetrahydrobipyran. (1994) (8)
- Copper‐Catalyzed Arylations of Amines and Alcohols with Boron‐Based Arylating Reagents (2009) (8)
- Synthesis of taurospongin A: a potent inhibitor of DNA polymerase and HIV reverse transcriptase, using pi-allyltricarbonyliron lactone complexes. (2002) (8)
- 5-Pyrrolidin-2-yltetrazole: A New, Catalytic, More Soluble Alternative to Proline in an Organocatalytic Asymmetric Mannich-Type Reaction. (2004) (8)
- The Total Synthesis of the Bioactive Natural Product Plantazolicin A and Its Biosynthetic Precursor Plantazolicin B. (2016) (8)
- Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin. (2008) (8)
- Total synthesis of the plasmoidal pigment physarorubinic acid, a polyenoyl tetramic acid (1999) (8)
- Organocatalysis with Proline Derivatives. Improved Catalysts for the Asymmetric Mannich, Nitro-Michael and Aldol Reactions. (2005) (8)
- Palladium Acetate in Polyurea Microcapsules: A Recoverable and Reusable Catalyst for Hydrogenations (2002) (8)
- A Convergent Continuous Multistep Process for the Preparation of C4-Oxime-Substituted Thiazoles (2018) (8)
- Synthese des Nonamannan‐Fragmentes eines stark mannosehaltigen Glycoproteins (1996) (8)
- Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives. (2006) (8)
- A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions (2020) (8)
- The use of t-butyl acetothioacetate as a route to bis-β-ketomacrolides (1985) (8)
- A General C-Glycosidation Procedure via Anomeric Oxygen to Carbon Rearrangements of Tetrahydropyranyl Ether Derivatives (1997) (8)
- Practical synthesis of (S)-pyrrolidin-2-yl-1H-tetrazole, incorporating efficient protecting group removal by flow-reactor hydrogenolysis (2006) (7)
- Formation of lactones from dienes via iron carbonyl complexes (1978) (7)
- Organic Chemistry in Microreactors (2008) (7)
- Chemistry of insect antifeedants from Azadirachta indica (Part 16): Synthesis of several derivatives of azadirachtin containing fluorescent or immunogenic reporter groups (1994) (7)
- Aryne chemistry. Part XXXV. Reactions of arynes with 1-aminocycloalkenes and hydrolyses of the adducts (1974) (7)
- The use of π-allyltricarbonyliron lactone complexes in the synthesis of the resorcylic macrolides α- and β-zearalenol (2000) (7)
- Rapid assembly of anti,anti-1,2,3-triol motifs via stereoselective addition of organometallics to aldehydes obtained from (R′,R′,S,R)-2,3-butane diacetal protected butanetetraol derivatives (2001) (7)
- Alkaloid Synthesis (2012) (7)
- Enantioselective Synthesis of the Tetrahydrobenzylisoquinoline Alkaloid (-)-Norarmepavine Using Polymer Supported Reagents (2003) (7)
- Thermal decomposition of tricarbonyliron lactone complexes (1980) (7)
- Reductive decomplexation of π-allyltricarbonyliron lactone complexes: a new route to stereodefined acyclic 1,5-diols and 1,5,7-triols (2000) (7)
- Oxidation of benzylic hydrocarbons with benzeneseleninic anhydride and related reactions (1982) (7)
- Use of Phenylsulphonylmethano Ethers in Synthesis: A New Versatile Route to Substituted Cyclic Ethers (1991) (7)
- Versatile solid-phase synthesis of secondary amines from alcohols. Development of an N-Boc-(o-nitrobenzene)sulfonamide linker (2003) (7)
- Development of an indole safety-catch linker using analytical constructs. (2004) (7)
- Synthesis of 3-Nitropyrrolidines via Dipolar Cycloaddition Reactions Using a Modular Flow Reactor. (2010) (7)
- Diastereoselective additions to aldehyde groups in the side-chain of π-allyltricarbonyliron lactone complexes (1996) (7)
- A General Organocatalytic Enantioselective Nitrocyclopropanation Reaction (2008) (7)
- In-line separation of multicomponent reaction mixtures using a new semi-continuous supercritical fluid chromatography system (2018) (7)
- Homotropylium-8-sulfinate complexes by antimony pentafluoride-promoted ring opening of 9-thiabicyclo[4.2.1]nona-2,4,7-triene and 9-thiabarbaralane 9,9-dioxides (1976) (7)
- Facilitating Biomimetic Syntheses of Borrerine Derived Alkaloids by Means of Flow-Chemical Methods* (2015) (7)
- Tetracyanoethylene addition to iron tricarbonyl complexes of substituted cyclooctatetraenes. Regioselectivity considerations during formation of the 2,3,4,10-tetrahapto adducts (1975) (6)
- Unimolecular and Supramolecular Electronics II: Chemistry and Physics Meet at Metal-Molecule Interfaces (2012) (6)
- A new synthetic approach towards adriamycin (1980) (6)
- Chemistry of insect antifeedants from Azadirachta indica(part 20): synthesis of biologically active, simple analogues of azadirachtin, containing the hydroxytetrahydrofurancarboxylate hemiketal moiety (1996) (6)
- Total synthesis of the potent antifungal agents bengazole C and E (2009) (6)
- A highly automated, polymer-assisted strategy for the preparation of 2-alkylthiobenzimidazoles and N,N'-dialkylbenzimidazolin-2-ones. (2005) (6)
- Stereoselective synthesis of (2R,3S,4S,5R)-trans-3,4-dihydroxy-5-(4-fluorophenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)tetrahydrofuran and (2R,3S,4S,5R)-trans-5-ethynyl-2-(4-fluorophenoxymethyl)-3,4-O-isopropylidene tetrahydrofuran from mannose diacetonide (2005) (6)
- Aryne chemistry. Part XXXIII. Reactions of tetrahalogenobenzynes with methoxyarenes and the photolysis and thermolysis of some of the products (1974) (6)
- Rearrangement reactions of bicyclic systems. Part II. Rearrangements of 1-dimethylamino-5,6,7,8-tetrahalogeno-1,4-dihydro-1,4-ethenonaphthalene derivatives and the analogous 5,6,7,8-tetrafluoro-1,4-dihydro-N-methyl-1,4-iminonaphthalene in aqueous solutions (1974) (6)
- Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from (S)- and (R)-glyceraldehyde derivatives ☆ (2005) (6)
- Use of S-t-butyl acetothioacetate in the preparation of milbemycin seco-analogues (1987) (6)
- Sir Derek Harold Richard Barton. 8 September 1918 – 16 March 1998 (2002) (6)
- Continuous Flow Ligand‐Free Heck Reactions Using Monolithic Pd(0) Nanoparticles. (2007) (6)
- Tritiated dihydroazadirachtin binding to Schistocerca gregaria testes and Spodoptera Sf9 cells suggests a similar cellular mechanism of action for azadirachtin. (1999) (6)
- Lesser‐Known Enabling Technologies for Organic Synthesis (2011) (6)
- Reaction of tetracycline hydrochloride with N-chlorosuccinimide: X-ray crystal structure of the major product (1977) (6)
- (S)‐5‐Pyrrolidin‐2‐Yl‐1H‐Tetrazole (2008) (6)
- Modeling mesoscale reactors for the production of fine chemicals (2015) (6)
- Polyurea‐Encapsulated Palladium(II) Acetate: A Robust and Recyclable Catalyst for Use in Conventional and Supercritical Media. (2002) (6)
- Highly diastereoselective synthesis of β-hydroxy carbonyl compounds using π-allyltricarbonyliron lactone complexes: a formal 1,7-asymmetric induction of chirality in a Mukaiyama aldol reaction (1998) (6)
- (1'S, 2'S)-METHYL-30,40-(1', 2' -DIMETHOXYCYCLOHEXANE-1', 2'-DIYL)-ALPHA -D-MANNOPYRANOSIDE : (ALPHA -D-MANNOPYRANOSIDE, METHYL 3,4-O-(1,2-DIMETHOXY-1 ,2 -CYCLOHEXANEDIYL)-, 3S(S)-) (1998) (6)
- Solid‐Supported Reagents for Multi‐Step Organic Synthesis: Preparation and Application. (2002) (6)
- The Synthesis of (-)-Gloeosporone, a Potent Fungal Autoinhibitor of Spore Germination Using a π-Allyltricarbonyliron Lactone Complex and a New Reductive Decomplexation Procedure for the Installation of the Embedded 1,7-Diol Component of the Natural Product (2004) (6)
- An Enantioselective Organocatalytic Route to Chiral 3,6-Dihydropyridazines from Aldehydes (2006) (6)
- OXIDATION OF KETONE AND ALDEHYDE HYDRAZONES, OXIMES, AND SEMICARBAZONES AND OF HYDROXYLAMINES AND HYDRAZO‐COMPOUNDS, USING BENZENESELENINIC ANHYDRIDE (1980) (6)
- Recent developments in natural product synthesis (1989) (6)
- Tuning the Reactivity of Glycosides: Efficient One‐Pot Oligosaccharide Synthesis. (2010) (5)
- Development of β-Keto 1,3-Dithianes as Versatile Intermediates for Organic Synthesis. (2003) (5)
- Synthesis of a trans-decalin as a potential insect antifeedant (1982) (5)
- A General Organocatalytic Enantioselective Nitrocyclopropanation Reaction. (2008) (5)
- Photoredox-Catalyzed Dehydrogenative Csp3-Csp2 Cross-Coupling of Alkylarenes to Aldehydes in Flow. (2021) (5)
- Synthesis of a substituted cis-decalin as a potential insect antifeedant (1980) (5)
- Microwave-Assisted Leimgruber—Batcho Reaction for the Preparation of Indoles, Azaindoles and Pyrroylquinolines. (2004) (5)
- Editorial – Flow Chemistry and Catalysis (2016) (5)
- A New World for Chemical Synthesis? (2019) (5)
- Polymer Supported Reagents in Synthesis: Preparation of Bicyclo[2.2.2]octane Derivatives via Tandem Michael Addition Reactions and Subsequent Combinatorial Decoration. (2000) (5)
- The synthesis of mono- and bicyclic ethers via acid catalysed ring-opening cyclisation of tetrahydropyranyl ether derivatives (2000) (5)
- Azeotropic reflux chromatography: an efficient solution to a difficult separation in the scale-up synthesis of spongistatin 1. (2008) (5)
- Living with our machines: Towards a more sustainable future (2020) (5)
- Preparation of the Neolignan Natural Product Grossamide by a Continuous-Flow Process. (2006) (5)
- Continuous Flow Hydration of Pyrazine-2-carbonitrile in a Manganese Dioxide Column Reactor (2017) (5)
- Chemistry of insect antifeedants from Azadirachta indica(part 13): on the use of the intramolecular Diels–Alder reaction for the construction of trans-fused hydrobenzofuran fragments for azadirachtin synthesis (1992) (5)
- Stereoselective synthesis of (2S,7S)-7-(4-phenoxymethyl)- 2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane: a potential anti-asthmatic drug candidate (2005) (5)
- Enantiopure 2-substituted glyceraldehyde derivatives by aza-Claisen rearrangement or C-alkylation of enamines. (2008) (5)
- Dehydrogenation of lactones using benzeneseleninic anhydride. X-Ray crystal structure of 3β-acetoxy-14α-hydroxy-17a-oxa-D-homo-5α-androst-15-en-17-one (1982) (5)
- The Use of Diethylaminosulfur Trifluoride (DAST) for Fluorination in a Continuous‐Flow Microreactor. (2008) (5)
- Further Reactions of t-Butyl 3-Oxobutanethioate and t-Butyl 4- Diethylphosphono-3-oxobutanethioate: Carbonyl Coupling Reactions, Amination, Use in the Preparation of 3-Acyltetramic Acids and Application to the Total Synthesis of Fuligorubin A. (1992) (5)
- 1,5-asymmetric induction of chirality using pi-allyltricarbonyliron lactone complexes: highly diastereoselective synthesis of alpha-functionalised carbonyl compounds. (2003) (5)
- Palladium Acetate in Polyurea Microcapsules: A Recoverable and Reusable Catalyst for Hydrogenations. (2003) (5)
- Enzymatic Oxidative Cyclisation Reactions Leading to Dibenzoazocanes (2010) (5)
- Synthesis of (±)-cis-6-methyltetrahydropyran-2-ylacetic acid, a natural product from Viverra civetta, using organoselenium-mediated cyclisation reactions (1984) (5)
- Rearrangement reactions of bicyclic systems. Part III. Acid-catalysed rearrangements of 1,4-dihydro-1-methoxy-1,4-ethenonaphthalene (1-methoxybenzobarrelene) and its 5,6,7,8-tetrahalogeno-derivatives (1974) (5)
- Enzymatic pretreatment of recycled grease trap waste in batch and continuous-flow reactors for biodiesel production (2021) (5)
- A Microfluidic Flow Chemistry Platform for Organic Synthesis: The Hofmann Rearrangement. (2009) (5)
- The Azadirachtin Story (2009) (5)
- Piperazic Acid-Containing Natural Products: Isolation, Biological Relevance and Total Synthesis (2011) (5)
- A multicomponent approach for the preparation of homoallylic alcohols (2016) (4)
- Engineering chemistry for the future of organic synthesis (2018) (4)
- Highly diastereoselective ketone aldol reactions of Butane-2,3-diacetal desymmetrised glycolic acid (2002) (4)
- A novel decomplexation of π-allyltricarbonyliron lactone complexes using borohydride reagents: a new route to stereodefined acyclic 1,5-diols and 1,5,7-triols (1998) (4)
- Synthesis of β-dimorphecolic acid exploiting highly stereoselective reduction of a side-chain carbonyl group in a π-allyltricarbonyliron lactone complex (1995) (4)
- Category 4, Compounds with Two Carbon Heteroatom Bonds (2007) (4)
- Development and application of a carbonyl-(13)C-enriched backbone amide linker for solid-phase reaction monitoring. (2001) (4)
- Selective Acylation and Alkylation Reactions of Diols Using Dibutyltin Dimethoxide. (1994) (4)
- Synthesis and reducibility of homo-2-methoxyazocines and their benzo-fused derivatives. An examination of heteroatomic influences on the possible generation of 9C-10.pi. homoaromatic dianions (1978) (4)
- Preparation and Use of Tetra-n-butylammonium Perruthenate (TBAP reagent) and Tetra-n-propylammonium Perruthenate (TPAP reagent) as New Catalytic Oxidants for Alcohols. (1988) (4)
- A Total Synthesis of Epothilones Using Solid‐Supported Reagents and Scavengers. (2003) (4)
- 1,2‐Diacetals: A New Opportunity for Organic Synthesis (2001) (4)
- The use of 3-acetoxy-1-trimethylsilylbutadiene in the synthesis of anthracyclinone derivatives (1984) (4)
- Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines (2017) (4)
- An unexpected rearrangement of 4-alkylaminoindoles (1983) (4)
- A Concise Synthesis of Carpanone Using Solid-Supported Reagents and Scavengers. (2003) (4)
- A Flow Process for the Multi‐Step Synthesis of the Alkaloid Natural Product Oxomaritidine: A New Paradigm for Molecular Assembly. (2006) (4)
- Regiospecific fragmentation of benzene derivatives: synthetic and analytical applications (1995) (4)
- Multi‐Step Synthesis by Using Modular Flow Reactors: The Preparation of Yne—Ones and Their Use in Heterocycle Synthesis. (2010) (4)
- On the reaction of thioacetals with sulphuryl chloride (1981) (4)
- Dispiroketals in synthesis (Part 16): Functionalised dispiroketals as new chiral auxiliaries; the synthesis of dihydroxylated dispiroketals in optically pure form and their application as bifunctional, C2-symmetrical, chiral auxiliaries for highly stereoselective Michael additions† (2010) (4)
- Total Synthesis of the Amaryllidaceae Alkaloid (+)‐Plicamine Using Solid‐Supported Reagents. (2002) (4)
- The Use of Polymer-Supported Reagents and Scavengers in the Synthesis of Natural Products (2006) (4)
- Natural Products as an Inspiration for the Discovery of New High‐Throughput Chemical Synthesis Tools (2006) (4)
- Rearrangement reactions of bicyclic systems. Part IV. Acid-catalysed rearrangements of 5,6,7,8-tetrafluoro-1,4-dihydro-1-methoxy-3,9-dimethyl-1,4-ethenonaphthalene (1-methoxy-3,5-dimethyltetrafluorobenzobarrelene) (1974) (4)
- Use of the Temporary Connection in Organic Synthesis (2007) (3)
- Titelbild: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. 40/2007) (2007) (3)
- Development of a web-based platform for studying lithiation reactions in silico. (2015) (3)
- Enantioselective Synthesisof the Lyngbouilloside Macrolactone Core (2009) (3)
- A New Focused Microwave Approach to the Synthesis of Amino-Substituted Pyrroloisoquinolines and Pyrroloquinolines via a Sequential Multi-Component Coupling Process (2008) (3)
- Twenty five years of azadirachtins (1986-2011) (2011) (3)
- Dispiroketals in Synthesis (Part 18)1: Regioselective and Enantioselective Protection of Symmetric Polyol Substrates Using an Enantiopure (2S,2’S)-Dimethyl-bis-dihydropyran (1995) (3)
- Syngas-Mediated C—C Bond Formation in Flow: Selective Rhodium-Catalyzed Hydroformylation of Styrenes. (2012) (3)
- Polymer‐Supported Hypervalent Iodine Reagents in “Clean” Organic Synthesis with Potential Application in Combinatorial Chemistry. (1999) (3)
- Tetra‐N‐propylammonium Perruthenate: A Case Study in Catalyst Recovery and Re‐Use Involving Tetraalkylammonium Salts. (2002) (3)
- Dispiroketals in Synthesis. Part 19. Dispiroketals as Enantioselective and Regioselective Protective Agents for Symmetric Cyclic and Acyclic Polyols. (1996) (3)
- An Enantioselective Organocatalytic Route to Chiral 3,6-Dihydropyridazines from Aldehydes. (2007) (3)
- The Continuous-Flow Synthesis of Styrenes Using Ethylene in a Palladium-Catalyzed Heck Cross-Coupling Reaction. (2012) (3)
- Solid-Supported Reagents for the Oxidation of Aldehydes to Carboxylic Acids. (2002) (3)
- Cover Picture: Multi‐Step Application of Immobilized Reagents and Scavengers: A Total Synthesis of Epothilone C (Chem. Eur. J. 10/2004) (2004) (3)
- Synthesis of a Ceramide Sphingolipid as a Potential Sex Pheromone of the Hair Crab Erimacrus isenbeckii Using Butane-2,3-diacetal Desymmetrised Glycolic Acid Building Blocks (2005) (3)
- Diastereoselective Synthesis of Functionalized Indolines Using in situ Generated Allyl Boronic Species (2017) (3)
- A Concise Synthesis of the Natural Product Carpanone Using Solid-Supported Reagents and Scavengers. (2002) (3)
- Transfer Hydrogenation Using Recyclable Polyurea‐Encapsulated Palladium: Efficient and Chemoselective Reduction of Aryl Ketones. (2003) (3)
- Automated multi-objective reaction optimisation: which algorithm should I use? (2022) (3)
- Synthesis of Trifluoromethylated Isoxazoles and Their Elaboration Through Inter‐ and Intra‐Molecular C—H Arylation. (2016) (3)
- A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides (2017) (3)
- Practical organocatalysis with (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles (2008) (3)
- Tri-n-butyl[2-(trimethylsilyl)-ethoxymethoxymethyl]stannane: A Convenient Hydroxymethyl Anion Equivalent (2000) (3)
- Synthesis of a Hydroxy Dihydrofuran Acetal Related to Azadirachtin: A Potent Insect Antifeedant. (1987) (3)
- Corrigendum to “Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors” [Eur. J. Med. Chem. 101 (2015) 573–583] (2015) (3)
- Therapeutic Inhibition of C-Reactive Protein-Novel Drugs, Novel Mechanisms (2003) (3)
- A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles (2009) (3)
- Total Synthesis of the Cyclic Heptapeptide Argyrin B (I): A New Potent Inhibitor of T-Cell Independent Antibody Formation. (2002) (3)
- Stereoelectronic effects in the reactions of conformationally restricted, substituted cyclohexane-1,2-diones with 1,2-diols (1998) (3)
- Reductive decomplexation of pi-allyltricarbonyliron lactone complexes; a new route to stereo-defined 1,7-diols and 2,3-diene-1,7-diols. (2002) (3)
- 8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction (2006) (3)
- Total Synthesis of the Ionophore Antibiotic CP‐61,405 (Routiennocin). (2010) (3)
- X-Ray evidence for partial bonding between sulphur or selenium and oxygen in thio- and seleno-imines (1977) (3)
- Polymer-Supported Reagents and Scavengers in Synthesis (2008) (3)
- Enantioselective Synthesis of the Tetrahydrobenzylisoquinoline Alkaloid (-)-Norarmepavine Using Polymer-Supported Reagents. (2004) (3)
- Flow Ozonolysis Using a Semipermeable Teflon AF-2400 Membrane (2010) (3)
- New Tools for Molecule Makers : Emerging Technologies (2009) (3)
- Multiple rearrangement reactions of 1-methoxybenzobarrelene (1,4-dihydro-1-methoxy-1,4-ethenonaphthalene) derivatives (1971) (3)
- A General Organocatalytic Enantioselective Malonate Addition to α,β-Unsaturated Enones. (2008) (2)
- Synthesis of Insect Antifeedants. (1993) (2)
- Clean Five-Step Synthesis of an Array of 1,2,3,4-Tetra-Substituted Pyrroles Using Polymer-Supported Reagents. (1999) (2)
- Pd‐EnCat TPP30 as a Catalyst for the Generation of Highly Functionalized Aryl‐ and Alkenyl‐Substituted Acetylenes via Microwave‐Assisted Sonogashira Type Reactions. (2010) (2)
- Rearrangement reactions of 1-NN-dimethylaminobenzobenzobarrelene derivatives (benzobarrelene = 1,4-dihydro-1,4-ethenonaphthalene) (1970) (2)
- Multicomponent Direct Assembly of N-Heterospirocycles Facilitated by Visible-Light-Driven Photocatalysis (2022) (2)
- Sulphuration of Electron-Rich Arenes with Sulphenamides and Aminosulphenyl Chlorides (1980) (2)
- Experiments on the synthesis of tetracycline. Part 16. Improved photocyclic preparation of 12-keto-derivatives and their deprotection using benzeneseleninic anhydride (1981) (2)
- Chemistry of insect antifeedants from Azadirachta indica. XIV: Absolute configuration of azadirachtin (1992) (2)
- Total synthesis of the phytotoxic agent herbarumin II using butane diacetals of glycolic acid as building blocks (2003) (2)
- Preface--In Honor of Professor Leo A. Paquette and on the Occasion of His 70th Birthday (This volume is dedicated to Prof. Leo A. Paquette on the occasion of his 70th birthday) (2004) (2)
- The Use of a Continuous Flow‐Reactor Employing a Mixed Hydrogen—Liquid Flow Stream for the Efficient Reduction of Imines to Amines. (2005) (2)
- 5‐Pyrrolidin‐2‐yltetrazole as an Asymmetric Organocatalyst for the Addition of Ketones to Nitro‐Olefins. (2005) (2)
- A Sequential Tetra‐n‐propylammonium Perruthenate (TPAP)—Wittig Oxidation Olefination Protocol. (2004) (2)
- Butane‐2,3‐diacetal‐desymmetrized Glycolic Acid — A New Building Block for the Stereoselective Synthesis of Enantiopure α‐Hydroxy Acids. (2001) (2)
- A Simple, One-Pot, Glycosidation Procedure via (1-Imidazolylcarbonyl) Glycosides and Zinc Bromide. (1990) (2)
- Thermal isomerization of homoazocines (1978) (2)
- Use of pi-allyltricarbonyliron lactone complexes in the synthesis of taurospongin A: a potent inhibitor of DNA polymerase beta and HIV revers transcriptase. (2003) (2)
- Benzotriazoles in Solid‐Phase Organic Chemistry (2003) (2)
- Three‐Step Synthesis of an Array of Substituted Benzofurans Using Polymer‐Supported Reagents. (2000) (2)
- Flow Oxidation Reactions Using Polystyrene-Supported Reagents (2011) (2)
- Grignard Additions to 2-Uloses: Synthesis of Stereochemically Pure Tertiary Alcohols. (2004) (2)
- New catalysts for olefin metathesis (2001) (2)
- Parallel Solution‐Phase Syntheses of Functionalized Bicyclo[2.2.2]octanes: Generation of a Library Using Orchestrated Multi‐step Sequences of Polymer‐Supported Reagents and Sequesterants. (2001) (2)
- Synthesis of Thapsigargin (2007) (2)
- A Rapid Stereocontrolled Synthesis of the 3a‐Hydroxy‐pyrrolo[2,3‐b]indole Skeleton, a Building Block for 10b‐Hydroxypyrazino[1′,2′:1,5]pyrrolo[2,3‐b]indole‐1,4‐diones. (2004) (2)
- Synthesis of Pyrroloisoquinolines via Multicomponent Condensation (2008) (2)
- A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane-1,2- diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide. (1997) (2)
- Dispiroketals in Synthesis. Part 2. A New Group for the Selective Protection of Diequatorial Vicinal Diols in Carbohydrates. (1993) (2)
- (π-Allyl)tricarbonyliron Lactone Complexes in Organic Synthesis: A Useful and Conceptually Unusual Route to Lactones and Lactams (1996) (2)
- A Rapid Approach for the Optimization of Polymer-Supported Reagents in Synthesis. (2001) (2)
- Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes. (2013) (2)
- Stereochemistry of a 5,5,10-trimethyl-2-decalone by proton nuclear magnetic resonance: a new application of INDOR difference spectroscopy (1983) (2)
- Catalytic Polymer-Supported Potassium Thiophenolate in Methanol as a Method for the Removal of Ester, Amide, and Thioacetate Protecting Groups (2004) (2)
- Organic Chemistry in Ionic Liquids Using Non-Thermal Energy Transfer Processes (2005) (2)
- Solid-Phase Reaction Monitoring: Chemical Derivatization and Off-Bead Analysis (2001) (2)
- Formation and Utility of Reactive Ketene Intermediates Under Continuous Flow Conditions (2021) (2)
- Synthesis of the C-1—C-28 ABCD Unit of Spongistatin 1. (2004) (2)
- Synthesis of Nornicotine, Nicotine and Other Functionalized Derivatives Using Solid-Supported Reagents and Scavengers. (2002) (2)
- A Continuous Flow Solution to Achieving Efficient Aerobic anti‐Markovnikov Wacker Oxidation. (2013) (2)
- Chromatography-Free Suzuki Reactions Using a Polymer-Assisted Solution-Phase (PASP) Approach (2007) (2)
- FeCl3-Catalysed Cleavage of 1,2-Butanediacetal Protected Diols (2008) (2)
- Synthesis and Modification of Azadirachtin and Related Antifeedants (1990) (2)
- Dispiroketals in Synthesis. Part 18. Regioselective and Enantioselective Protection of Symmetric Polyol Substrates Using an Enantiopure (2S,2′S)‐Dimethyl‐bis‐dihydropyran. (1996) (2)
- Borohydride Exchange Resin (2002) (2)
- Structure activity relationships in azadirachtin A derivatives: Feeding activity and degree of efficiency tested on Epilachna varivestis larvae (1999) (2)
- Stereoselective synthesis of chiral tetrahydrofurans with potent 5-LO inhibitory activity ☆ (2005) (2)
- Clean Six‐Step Synthesis of a Piperidino‐thiomorpholine Library Using Polymer‐Supported Reagents. (1999) (2)
- Synthesis of Highly Substituted Nitropyrrolidines, Nitropyrrolizines and Nitropyrroles via Multicomponent-Multistep Sequences within a Flow Reactor. (2011) (2)
- Acid-catalysed rearrangements of 3,5-dimethyl-1-methoxy-tetrafluorobenzobarrelene (5,6,7,8-tetrafluoro-1,4-dihydro-3,10-dimethyl-1-methoxy-1,4-ethenonaphthalene) (1971) (2)
- A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins (2005) (2)
- 3.35 – Polymer-Supported Reagents and Scavengers in Synthesis (2007) (2)
- Preparation of Enantiopure Butane‐2,3‐diacetals of Glycolic Acid and Alkylation Reactions Leading to α‐Hydroxyacid and Amide Derivatives. (2005) (2)
- The formation of unusual sultones during the rearrangement reactions of bicyclic ketones (1978) (2)
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- Wittig and Horner-Wittig Coupling Reactions of 2-Substituted Cyclic Ethers and Their Application to Spiroketal Synthesis. (1985) (0)
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- Microbial Oxidation in Synthesis: Preparation of 6-Deoxycyclitol Analogues of myo-Inositol 1,4,5-Trisphosphate from Benzene. (1990) (0)
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- Data supporting "Continuous preparation and use of dibromoformaldoxime as a reactive intermediate for the synthesis of 3-bromoisoxazolines" (2017) (0)
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- A Short and Efficient Stereoselective Synthesis of the Potent 5-Lipoxygenase Inhibitor, CMI-977. (2010) (0)
- A Polymer‐Supported Thionating Reagent. (2001) (0)
- New Building Blocks for Efficient and Highly Diastereoselective Polyol Production. Synthesis and Utility of (R′,R′,S,S) and (S′,S′,R,R)‐2,3‐Butane Diacetal Protected Butane Tetrol Derivatives. (1999) (0)
- Reductive Decomplexation of π‐Allyltricarbonyliron Lactone Complexes; a New Route to Stereo‐Defined 1,7‐Diols and 2,3‐Diene‐1,7‐diols. (2003) (0)
- A Flow Reactor Process for the Synthesis of Peptide Utilizing Immobilized Reagents, Scavengers and Catch and Release Protocols. (2007) (0)
- Synthesis of (–)-GB17 (2012) (0)
- Enantioselective Synthesis of Pumiliotoxin C and trans-195A (2012) (0)
- Organic Synthesis in a Changing World (2003) (0)
- A Route to the Thapsigargins from (S)‐Carvone Providing a Substrate‐Controlled Total Synthesis of Trilobolide (Ia), Nortrilobolide (Ib), and Thapsivillosin F (Ic). (2004) (0)
- Synthesis of (±)-Dragmacidin E (2012) (0)
- CCDC 252366: Experimental Crystal Structure Determination (2006) (0)
- A General Organocatalytic Enantioselective Nitrocyclopropanation Reaction Enantioselective Nitrocyclopropanation Reaction (2008) (0)
- Application of Ultrasound to the Preparation of Organolithiums (1989) (0)
- Novel palindromic ligands cementing the native quaternary structure of transthyretin (2010) (0)
- CHAPTER 19. Process Intensification: From Green Chemistry to Continuous Processing (2021) (0)
- SYNTHESIS OF β-LACTAMS FROM Π-ALLYLTRICARBONYLIRON (LACTONE) COMPLEXES (1984) (0)
- Sulfone–Lactone Coupling Reactions (2007) (0)
- Diastereoselective Oxygen to Carbon Rearrangements of Anomerically Linked Enol Ethers and the Total Synthesis of (+)-(S,S)-(cis-6-Methyltetrahydropyran-2-yl)acetic Acid, a Component of Civet. (2000) (0)
- A Clean Conversion of Aldehydes to Nitriles Using a Solid-Supported Hydrazine. (2010) (0)
- Reactions with Other Alkali Metals (1989) (0)
- Highly Diastereoselective Desymmetrization of Cyclic meso-Anhydrides and Derivatization to Mono-Protected 1,4-Diols. (2005) (0)
- Oxidative Insertion Reactions (2007) (0)
- In silico rationalisation of selectivity and reactivity in Pd-catalysed C–H activation reactions (2020) (0)
- Highly diastereoselective Michael addition reactions of butane-2,3-diacetal desymmetrized glycolic acid. Preparation of alpha-hydroxy-gamma-amino acid derivatives. (2001) (0)
- Microwave-Assisted Sonogashira-Type Reaction Using Pd-EnCat (2009) (0)
- Synthesis of the Northern Hemisphere of the Milbemycins Using a New Strategy for the Formation of the C-15 to C-16 Bond. (1986) (0)
- Hetero-Diels–Alder Reactions (2007) (0)
- SYNTHESIS OF SPIROACETALS USING ORGANOSELENIUM-MEDIATED CYCLIZATION REACTIONS. X-RAY MOLECULAR STRUCTURE O (2S,8R)-8-METHYL-2-PHENYL-1,7-DIOXASPIRO(5.5)UNDECAN-4(R)-OL (1984) (0)
- Chemistry of Insect Antifeedants from Azadirachta indica. Part 7. Preparation of an Optically Pure Hydroxyacetal Epoxide (II) Related to Azadirachtin. (1991) (0)
- Mukaiyama Aldol Reactions of π-Allyltricarbonyliron Lactone and Lactam Complexes Bearing Trimethylsilyl Enol Ether Side-Chains. Not Just Formal, but Genuine 1,7-Induction of Chirality. (1998) (0)
- Research data supporting “Rapid asymmetric disubstituted allene synthesis via coupling of flow-generated diazo compounds and propargylated amines” (2016) (0)
- Direct Substitution of 2-Benzenesulfonylpiperidines and -pyrrolidines by Carbon Nucleophiles: Synthesis of the Pyrrolidine Alkaloid Ruspolinone. (1990) (0)
- Anomeric oxygen to carbon rearrangements of alkynyl tributylstannane derivatives of furanyl (gamma)- and pyranyl (delta)-lactols. (2004) (0)
- Chemistry of Insect Antifeedants from Azadirachta indica. Part 21. Synthesis of Model Compounds of Azadirachtin Using a Decalin Framework as a Functional Group Scaffolding. (1996) (0)
- Research data supporting “A Parallel Column Supercritical Fluid Chromatography System for Continuous Purification” (2016) (0)
- EXPERIMENTS ON THE SYNTHESIS OF TETRACYCLINE. PART 16. IMPROVED PHOTOCYCLIC PREPARATION OF 12-KETO DERIVATIVES AND THEIR DEPROTECTION USING BENZENESELENINIC ANHYDRIDE (1981) (0)
- Synthesis of Hyperpapuanone (2012) (0)
- Ultrasonic Acceleration of Redox Reactions (1989) (0)
- Exploring the chemical space of phenyl sulfide oxidation by automated optimization (2023) (0)
- Synthesis and Chemistry of the Ionophore Antibiotic Tetronasin (2010) (0)
- Data supporting "Photochemical homologation for the preparation of aliphatic aldehydes in flow" (2019) (0)
- Highly Diastereoselective Michael Addition Reactions of Butane-2,3-diacetal Desymmetrized Glycolic Acid. Preparation of α-Hydroxy-γ-amino Acid Derivatives. (2002) (0)
- Stereoelectronic Effects in the Reactions of Conformationally Restricted, Substituted Cyclohexane-1,2-diones with 1,2-Diols. (1998) (0)
- THE QUESTION OF DELOCALIZATION IN ′ANCHORED′ IONS WITH POTENTIAL TRISHOMOAROMATIC CHARACTER. 1. REDUCTION OF TRICYCLO(5.4.1.04,12)DODECA-2,5,8,10-TETRAENE AS A ROUTE TO THE 10Π11C DIANION (1977) (0)
- Polymer-Supported Reagents as Versatile Tools in Combinatorial Chemistry and Total Synthesis (2000) (0)
- SULFURATION OF ELECTRON-RICH ARENES WITH SULFENAMIDES AND AMINOSULFENYL CHLORIDES (1980) (0)
- Clean Three‐Step Synthesis of 4,5‐Dihydro‐1H‐pyrazoles Starting from Alcohols Using Polymer Supported Reagents. (1998) (0)
- Synthesis of ent-Palmyrolide A (2012) (0)
- Synthesis of (+)-Taxadiene (2012) (0)
- The Use of tert-Butyl Acetothioacetate as a Route to Bis-β-ketomacrolides. (1986) (0)
- Enolate Addition to an Aldehyde (2007) (0)
- Diastereoselective Anomeric Oxygen to Carbon Rearrangements of Silyl Enol Ether Derivatives of Lactols. (1999) (0)
- Synthesis of (+)-Chimonanthine (2012) (0)
- Intramolecular Epoxide Ring Opening (2007) (0)
- Synthetic Studies Towards the Acyltetronic Acid Ionophore M 139603. (1986) (0)
- Chapter 8:Engineering Chemistry to Enable Bioactive Small Molecule Discovery (2018) (0)
- REARRANGEMENT REACTIONS OF BICYCLIC SYSTEMS PART 2, REARRANGEMENTS OF 1-DIMETHYLAMINO-5,6,7,8-TETRAHALOGENO-1,4-DIHYDRO-1,4-ETHENONAPHTHALENE DERIVATIVES AND THE ANALOGOUS 5,6,7,8-TETRAFLUORO-1,4-DIHYDRO-N-METHYL-1,4-IMINONAPHTHALENE (1975) (0)
- Relay Synthesis of Azadirachtin (2008) (0)
- Oxygen to Carbon Rearrangements of Anomerically Linked Alkenols from Tetrahydropyran Derivatives: An Investigation of the Reaction Mechanism via a Double Isotopic Labeling Crossover Study. (2000) (0)
- Total Synthesis of (±)−Agelastatin A (2012) (0)
- REARRANGEMENT REACTIONS OF BICYCLIC SYSTEMS PART 3, ACID-CATALYSED REARRANGEMENTS OF 1,4-DIHYDRO-1-METHOXY-1,4-ETHENONAPHTHALENE (1-METHOXYBENZOBARRELENE) AND ITS 5,6,7,8-TETRAHALOGENO-DERIVATIVES (1975) (0)
- Synthesis of (±)-Peribysin E (2012) (0)
- Preparation of Cyclic Ether Acetals from 2-Benzenesulfonyl Derivatives: A New Mild Glycosidation Procedure. (1989) (0)
- Evolving Cascades: The Claisen Rearrangement in the Development of Tandem Sequences of Three or More Reactions (2005) (0)
- Synthesis of Anominine and Tubingensin A (2012) (0)
- Cover Picture: The Synthesis of Azadirachtin: A Potent Insect Antifeedant (Chem. Eur. J. 34/2008) (2008) (0)
- A Highly Selective, Organocatalytic Route to Chiral 1,2‐Oxazines from Ketones. (2006) (0)
- Synthesis of (–)-Hanishin, (–)-Longamide B and (–)-Longamide B Methyl Ester (2012) (0)
- Synthesis of 4-Substituted Imidazoles via 4-Metalloimidazole Intermediates. (1994) (0)
- CATALYTIC OXIDATION OF THIOCARBONYL COMPOUNDS INVOLVING THE USE OF 1,2-DIBROMOTETRACHLOROETHANE AS A BROMINATING REAGENT FOR DIARYL TELLURIUM(II) SPECIES (1980) (0)
- Iridium-Catalyzed Reactions (2007) (0)
- Dispiroketals in Synthesis. Part 12. Functionalized Dispiroketals as New Chiral Auxiliaries: The Synthesis of Dihydroxylated Dispiroketals in Optically Pure Form. (2010) (0)
- A New Route to Functionalized π-Allyltricarbonyliron Lactam Complexes from Aziridines and Their Use in Stereoselective Synthesis and Oxidative Conversion to β-Lactams. (1999) (0)
- REARRANGEMENT REACTIONS OF BICYCLIC SYSTEMS PART 1, SYNTHESIS OF A MODEL COMPOUND RELATED TO FLAVOTHEBAONE TRIMETHYL ETHER, THE ABNORMAL ULTRAVIOLET ABSORPTION SPECTRUM OF FLAVOTHEBAONE AND ITS TRIMETHYL ETHER (1973) (0)
- Research data supporting "Utilization of flow chemistry in catalysis: new avenues for the selective synthesis of Bis(indolyl)methanes" (2016) (0)
- CYCLIZATION REACTIONS OF ALKENYL β-OXOESTERS INVOLVING A NOVEL PHENYLSELENO GROUP MIGRATION (1981) (0)
- Csp-H bonds using in-situ generated trifluoromethylated dioxirane in flow (2018) (0)
- Synthetic Studies Towards the Clerodane Insect Antifeedant Jodrellin A: Preparation of a Polycyclic Model Compound (XVIII) with Antifeedant Activity. (1996) (0)
- Acid-Catalyzed Carbonyl Cascade Process (2007) (0)
- A divergent approach to benzylisoquinoline-type and oxoaporphine alkaloids via regioselective direct ring metalation of alkoxy isoquinolines (2015) (0)
- Assessment of Butene-1,4-diols as Starting Materials for the Preparation of π-Allyltricarbonyliron Complexes. (1990) (0)
- Synthesis of (+)-Ambuic Acid (2012) (0)
- Synthesis of (±)-Mevashuntin (2012) (0)
- Teflon AF-2400 Mediated Gas—Liquid Contact in Continuous Flow Methoxycarbonylations and in-line FTIR Measurement of CO Concentration. (2012) (0)
- Anionic Acylation Reactions (2007) (0)
- AuCl3-Catalyzed Hydroalkoxylation of Conjugated Alkynoates: Synthesis of Five- and Six-Membered Cyclic Acetals. (2009) (0)
- 5-pyrrolidin-2-yl tetrazole (2009) (0)
- NITROGEN ANALOGS OF 1,6-METHANO(12)ANNULENE. EFFECT ON VALENCE TAUTOMERISM OF THE LOCUS OF AZA SUBSTITUTION (1975) (0)
- Synthesis Using Acetals Derived from Lactones (2007) (0)
- Total Synthesis of the Phytotoxic Agent Herbarumin II Using Butane Diacetals of Glycolic Acid as Building Blocks. (2003) (0)
- Synthesis of the Acyltetronic Acid Ionophore Tetronasin (ICI M139603). (1998) (0)
- Synthesis of β‐Dimorphecolic Acid Exploiting Highly Stereoselective Reduction of a Side‐Chain Carbonyl Group in a π‐ Allyltricarbonyliron Lactone Complex. (2010) (0)
- Using Nitro-Stabilized Anions (2007) (0)
- Total Synthesis of Agglomerin A and (.+-.)-Carolinic Acid. A General Method for the Preparation of 3-Acyl Tetronic Acids via Direct Acylation of O-Methyl 3-Stannyl Tetronates. (1992) (0)
- A 2,3‐Butanedione Protected Chiral Glycine Equivalent — A New Building Block for the Stereoselective Synthesis of Enantiopure N‐Protected α‐Amino Acids. (2003) (0)
- Four carbon-heteroatom bonds : X-C≡X, X=C=X, X[2]C=X, CX[4] (2005) (0)
- Carbonate, Polymer‐supported (2002) (0)
- Synthesis of the Amathaspiramides (2012) (0)
- Non‐Metal‐Catalyzed Intramolecular Alkyne Cyclotrimerization Reactions Promoted by Focussed Microwave Heating in Batch and Flow Modes. (2006) (0)
- N-ALKYLIERUNG VON INDOL UND PYRROLEN IN DIMETHYLSULFOXID (1973) (0)
- UMLAGERUNGSRK. VON 1-METHOXYBENZOBARRELEN (1,4-DIHYDRO-1-METHOXY-1,4-AETHENO-NAPHTHALIN)-DERIVATEN (1971) (0)
- UMLAGERUNGSRK. VON 1-N,N-DIMETHYLAMINOBENZOBARRELEN-DERIVATEN (BENZOBARRELEN=1,4-DIHYDRO-1,4-AETHENONAPHTHALIN) (1970) (0)
- SAEURE-KATALYSIERTE UMLAGERUNGEN VON 3,5-DIMETHYL-1-METHOXY-TETRAFLUOR-BENZOBARRELEN (5,6,7,8-TETRAFLUOR-1,4-DIHYDRO-3,10-DIMETHYL-1-METHOXY-1,4-AETHENONAPHTHALIN) (1972) (0)
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