Stewart Cole

Q: What Schools Are Affiliated With Stewart Cole

Stewart Cole is affiliated with the following schools: University of Sheffield, Imperial College London, École Polytechnique Fédérale de Lausanne, University of Wales, Cornell University, University of Bern, Monash University, Colorado State University, Harvard University

Stewart Cole's AcademicInfluence.com Rankings

Stewart Cole

Biology

#1777

World Rank

#2889

Historical Rank

Microbiology

#68

World Rank

#87

Historical Rank

biology Degrees

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Biology

Why Is Stewart Cole Influential?

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According to Wikipedia, Sir Stewart Thomas Cole is a British/French microbiologist. He has been the director general of the Pasteur Institute since January 2018. Early life and education Cole grew up in Wales, where he was educated at Milford Haven Grammar School and then at Ardwyn Grammar School, Aberystwyth. Following a life-threatening bout of paratyphoid he developed an interest in bacteria, viruses and infectious diseases, which led to his reading microbiology at the University of Wales, in Cardiff followed by research for his PhD at the University of Sheffield, England. Subsequently, he was a postdoctoral fellow at the University of Umeå and a research assistant at the Max-Planck-Institut for Biology, Tübingen .

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Stewart Cole's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence (1998) (7740)
Massive gene decay in the leprosy bacillus (2001) (1664)
A new evolutionary scenario for the Mycobacterium tuberculosis complex (2002) (1328)
Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis (1993) (1297)
The catalase—peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis (1992) (1252)
Nucleotide sequence of the AIDS virus, LAV (1985) (1206)
Sequences Human Induced Pluripotent Stem Cells Free of Vector and Transgene (2012) (1044)
The complete genome sequence of Mycobacterium bovis (2003) (957)
Advances in the development of new tuberculosis drugs and treatment regimens (2013) (774)
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti (2002) (713)
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis (2003) (652)
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis (2009) (619)
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. (2002) (585)
Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus (1985) (551)
Genome plasticity of BCG and impact on vaccine efficacy (2007) (549)
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays (1999) (547)
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. (2008) (519)
Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations (1994) (484)
On the origin of leprosy (2005) (438)
TubercuList--10 years after. (2011) (411)
Molecular genetics and pathogenesis of Clostridium perfringens. (1991) (403)
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. (2007) (367)
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. (2004) (355)
Comparative genomic and phylogeographic analysis of Mycobacterium leprae (2009) (353)
Mechanisms of drug resistance in Mycobacterium tuberculosis. (1994) (351)
Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level (1997) (349)
Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis (2014) (348)
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy (2003) (339)
Missense mutations in the catalase‐peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis (1995) (332)
Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomaviruses and repeated structure of the E6 and E7 gene products. (1987) (330)
Analysis of the proteome of Mycobacterium tuberculosis in silico. (1999) (330)
ESAT-6 proteins: protective antigens and virulence factors? (2004) (328)
New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects. (2014) (308)
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1. (2015) (307)
Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence (2006) (306)
ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity (2007) (306)
Rapid and Simple Approach for Identification of Mycobacterium tuberculosis Complex Isolates by PCR-Based Genomic Deletion Analysis (2002) (295)
Genome-Wide Comparison of Medieval and Modern Mycobacterium leprae (2013) (295)
The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes. (2011) (293)
Towards a new combination therapy for tuberculosis with next generation benzothiazinones (2014) (291)
Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study (1994) (288)
Systematic Genetic Nomenclature for Type VII Secretion Systems (2009) (288)
High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors (2009) (286)
Are the PE‐PGRS proteins of Mycobacterium tuberculosis variable surface antigens? (2002) (276)
Effect of katG Mutations on the Virulence of Mycobacterium tuberculosis and the Implication for Transmission in Humans (2002) (275)
Drug-resistant tuberculosis: time for visionary political leadership. (2013) (263)
Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP (2008) (263)
An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae. (1996) (257)
Identification of the Escherichia coli K‐12 Nramp orthologue (MntH) as a selective divalent metal ion transporter (2000) (232)
Tuberculosis biomarkers discovery: developments, needs, and challenges. (2013) (217)
The evolution of mycobacterial pathogenicity: clues from comparative genomics. (2001) (213)
Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis (1993) (212)
Rapid Mycobacterium species assignment and unambiguous identification of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis by automated DNA sequencing. (1995) (207)
Streptomycin resistance in mycobacteria (1994) (205)
Tuberculosis and the tubercle bacillus. (2005) (203)
Impact of Mycobacterium ulcerans Biofilm on Transmissibility to Ecological Niches and Buruli Ulcer Pathogenesis (2007) (200)
Use of a Mycobacterium tuberculosisH37Rv Bacterial Artificial Chromosome Library for Genome Mapping, Sequencing, and Comparative Genomics (1998) (197)
Probable zoonotic leprosy in the southern United States. (2011) (188)
The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid‐borne (1995) (188)
Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative‐stress regulatory gene:implications for sensitivity to isoniazid (1995) (187)
The Ser/Thr Protein Kinase PknB Is Essential for Sustaining Mycobacterial Growth (2006) (187)
Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex. (2004) (183)
Molecular basis of rifampin resistance in Mycobacterium leprae (1993) (181)
Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases (2014) (180)
Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli. (1986) (179)
Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis. (2010) (178)
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans (2009) (175)
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis. (2005) (173)
Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential. (2008) (172)
PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho‐Ser/Thr phosphatase, in Mycobacterium tuberculosis (2003) (171)
Genome organization and nucleotide sequence of human papillomavirus type 33, which is associated with cervical cancer (1986) (170)
Genome organization of the anaerobic pathogen Clostridium perfringens. (1989) (169)
Comparative and functional genomics of the Mycobacterium tuberculosis complex. (2002) (167)
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis (2012) (165)
Mycobacterium tuberculosis and the host response (2005) (164)
Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions. (2005) (161)
Mechanisms of drug resistance in Mycobacterium tuberculosis. (1996) (155)
Molecular biology, biochemistry and bioenergetics of fumarate reductase, a complex membrane-bound iron-sulfur flavoenzyme of Escherichia coli. (1985) (154)
Tuberculosis drug discovery in the post-post-genomic era (2014) (154)
Molecular genetic analysis of FNR‐dependent promoters (1989) (151)
Bacterial Artificial Chromosome-Based Comparative Genomic Analysis Identifies Mycobacterium microti as a Natural ESAT-6 Deletion Mutant (2002) (151)
Towards a new tuberculosis drug: pyridomycin – nature's isoniazid (2012) (151)
Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin (2005) (146)
Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringens (1992) (145)
Functional Analysis of Early Secreted Antigenic Target-6, the Dominant T-cell Antigen of Mycobacterium tuberculosis, Reveals Key Residues Involved in Secretion, Complex Formation, Virulence, and Immunogenicity* (2005) (145)
Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1. (2012) (144)
Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli (1988) (143)
Regulation of catalase–peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis (2001) (141)
Nucleotide sequence coding for the flavoprotein subunit of the fumarate reductase of Escherichia coli. (2005) (138)
Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products. (1988) (137)
Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone (2007) (137)
Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System1 (2005) (136)
A rapid method for the detection of potentially viable Mycobacterium leprae in human biopsies: a novel application of PCR. (1989) (130)
Aquatic Snails, Passive Hosts of Mycobacterium ulcerans (2004) (129)
Learning from the genome sequence of Mycobacterium tuberculosis H37Rv (1999) (129)
Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis (2010) (128)
Comparative Genomics Uncovers Large Tandem Chromosomal Duplications in Mycobacterium Bovis BCG Pasteur (2000) (125)
Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis (1997) (122)
Mycobacterium leprae: genes, pseudogenes and genetic diversity. (2011) (120)
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein (2012) (120)
The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis (2014) (119)
Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae (1993) (119)
Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis (2015) (118)
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1 (2015) (117)
Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis. (1999) (116)
Red squirrels in the British Isles are infected with leprosy bacilli (2016) (116)
Comparative genomics of the mycobacteria. (2000) (115)
Characterization of Active Site Structure in CYP121 (2008) (114)
An Increase in Antimycobacterial Th1-Cell Responses by Prime-Boost Protocols of Immunization Does Not Enhance Protection against Tuberculosis (2006) (113)
Analysis of the genome of Mycobacterium tuberculosis H37Rv. (1998) (113)
Differential Effects of Prior Exposure to Environmental Mycobacteria on Vaccination with Mycobacterium bovis BCG or a Recombinant BCG Strain Expressing RD1 Antigens (2005) (112)
Nucleotide sequence of the first cosmid from the Mycobacterium leprae genome project: structure and function of the Rif‐Str regions (1993) (111)
Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics. (2005) (110)
New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosis H37Rv. (1999) (106)
Location and nucleotide sequence of frdB, the gene coding for the iron-sulphur protein subunit of the fumarate reductase of Escherichia coli. (1982) (106)
Colonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone (2005) (105)
In Vitro Combination Studies of Benzothiazinone Lead Compound BTZ043 against Mycobacterium tuberculosis (2012) (105)
Bacterial genomics. (1994) (102)
Physical mapping of Mycobacterium bovis BCG pasteur reveals differences from the genome map of Mycobacterium tuberculosis H37Rv and from M. bovis. (1996) (101)
Genomic organization of the mycobacterial sigma gene cluster. (1995) (101)
DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization. (2015) (101)
Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB, two virulence‐plasmid genes of Kiebsiella pneumoniae (1989) (101)
Characterization of the highly abundant polymorphic GC-rich-repetitive sequence (PGRS) present in Mycobacterium tuberculosis (1995) (100)
A Point Mutation in the Two-Component Regulator PhoP-PhoR Accounts for the Absence of Polyketide-Derived Acyltrehaloses but Not That of Phthiocerol Dimycocerosates in Mycobacterium tuberculosis H37Ra (2007) (98)
Inactivation of Rv2525c, a Substrate of the Twin Arginine Translocation (Tat) System of Mycobacterium tuberculosis, Increases β-Lactam Susceptibility and Virulence (2006) (98)
Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis (2015) (97)
Comparative mycobacterial genomics as a tool for drug target and antigen discovery (2002) (97)
Cloning, sequencing, and expression of the apa gene coding for the Mycobacterium tuberculosis 45/47-kilodalton secreted antigen complex (1995) (96)
The decaying genome of Mycobacterium leprae. (2001) (96)
Structure and Mechanism of the Alkyl Hydroperoxidase AhpC, a Key Element of the Mycobacterium tuberculosis Defense System against Oxidative Stress* (2005) (96)
Zoonotic Leprosy in the Southeastern United States (2015) (95)
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe (2018) (93)
Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009–15 (2018) (93)
Leads for antitubercular compounds from kinase inhibitor library screens. (2010) (92)
Cell Envelope Protein PPE68 Contributes to Mycobacterium tuberculosis RD1 Immunogenicity Independently of a 10-Kilodalton Culture Filtrate Protein and ESAT-6 (2004) (91)
New tuberculosis drugs on the horizon. (2011) (91)
Erratum: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence (1998) (91)
Who will develop new antibacterial agents? (2014) (91)
Genomics of Mycobacterium bovis. (2001) (90)
Genomic Analysis Reveals Variation between Mycobacterium tuberculosis H37Rv and the AttenuatedM. tuberculosis H37Ra Strain (1999) (90)
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals Are Uniformly Susceptible to Benzothiazinones (2010) (90)
Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases. (2005) (88)
Cloning, mapping, and molecular characterization of the rRNA operons of Clostridium perfringens (1991) (87)
A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial. (2008) (87)
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. (2004) (86)
Complete nucleotide sequence and genetic organization of the bacteriocinogenic plasmid, pIP404, from Clostridium perfringens. (1988) (86)
Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis (1996) (85)
Identification of Specific Proteins and Peptides in Mycobacterium leprae Suitable for the Selective Diagnosis of Leprosy1 (2005) (85)
Rising standards for tuberculosis drug development. (2008) (85)
Common Evolutionary Origin for the Unstable Virulence Plasmid pMUM Found in Geographically Diverse Strains of Mycobacterium ulcerans (2005) (83)
Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12 (1988) (83)
Nucleotide sequence and transcriptional startpoint of the glpT gene of Escherichia coli: extensive sequence homology of the glycerol‐3‐phosphate transport protein with components of the hexose‐6‐phosphate transport system (1987) (82)
Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR (2008) (82)
2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1. (2015) (82)
Characterization of a bacteriocinogenic plasmid from Clostridium perfringens and molecular genetic analysis of the bacteriocin-encoding gene (1986) (82)
Regulation of enterobacterial cephalosporinase production: the role of a membrane‐bound sensory transducer (1989) (80)
Molecular characterization of the gene encoding SHV-3 beta-lactamase responsible for transferable cefotaxime resistance in clinical isolates of Klebsiella pneumoniae (1989) (79)
Purification, characterization, gene sequence, and significance of a bacterioferritin from Mycobacterium leprae (1994) (78)
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis (2016) (78)
Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis (2012) (77)
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression (2017) (76)
Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion. (2014) (76)
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans. (2005) (75)
A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling. (2008) (75)
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis. (2011) (74)
Identification of novel VirR/VirS‐regulated genes in Clostridium perfringens (2000) (74)
Development of a repressible mycobacterial promoter system based on two transcriptional repressors (2010) (74)
A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis. (2009) (74)
Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae (2018) (73)
EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis (2011) (73)
A Comprehensive Survey of Single Nucleotide Polymorphisms (SNPs) across Mycobacterium bovis Strains and M. bovis BCG Vaccine Strains Refines the Genealogy and Defines a Minimal Set of SNPs That Separate Virulent M. bovis Strains and M. bovis BCG Strains (2009) (72)
EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX‐1 secretion (2017) (71)
Export of a protein into the outer membrane of Escherichia coli K12. Stable incorporation of the OmpA protein requires less than 193 amino-terminal amino-acid residues. (1982) (71)
Mycobacterium tuberculosis: drug-resistance mechanisms. (1994) (71)
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance (2010) (71)
Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity. (2009) (71)
Genome‐wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis (2009) (70)
Repetitive sequences in Mycobacterium leprae and their impact on genome plasticity. (2001) (69)
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. (2016) (68)
Multiple regulatory elements for the glpA operon encoding anaerobic glycerol-3-phosphate dehydrogenase and the glpD operon encoding aerobic glycerol-3-phosphate dehydrogenase in Escherichia coli: further characterization of respiratory control (1990) (67)
Overview of Clinical Tuberculosis (2005) (67)
Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis (1995) (67)
Studies of UV‐inducible promoters from Clostridium perfringens in vivo and in vitro (1988) (66)
Assessing the essentiality of the decaprenyl‐phospho‐d‐arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants (2014) (66)
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA‐independent virulence (2013) (65)
A strategy to halt leprosy transmission. (2014) (65)
Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis. (2017) (64)
Comparative mycobacterial genomics. (1998) (63)
Comparative Genomics of esx Genes from Clinical Isolates of Mycobacterium tuberculosis Provides Evidence for Gene Conversion and Epitope Variation (2011) (63)
Molecular genetic analysis of the nagH gene encoding a hyaluronidase of Clostridium perfringens (1994) (63)
Characterization of two genes, glpQ and ugpQ, encoding glycerophosphoryl diester phosphodiesterases of Escherichia coli (1991) (62)
Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic (2014) (61)
Isolation of Three Mycobacterium ulcerans Strains Resistant to Rifampin after Experimental Chemotherapy of Mice (2003) (61)
Antigen Discovery: a Postgenomic Approach to Leprosy Diagnosis (2006) (60)
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG (2015) (60)
Genome mapping ofClostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne (1996) (60)
GenotypicAnalysis of Mycobacterium tuberculosis in Bangladesh andPrevalence of the BeijingStrain (2004) (58)
Cloning and molecular characterization of the ompA gene from Salmonella typhimurium. (1983) (57)
The nucleotide sequence coding for major outer membrane protein OmpA of Shigella dysenteriae. (1982) (57)
Protection against Mycobacterium ulcerans Lesion Development by Exposure to Aquatic Insect Saliva (2007) (57)
Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos (2018) (56)
The molecular basis of isoniazid resistance in Mycobacterium tuberculosis. (1999) (56)
Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. (2014) (56)
A family of dispersed repeats in Mycobacterium leprae (1990) (55)
Leprosy, tuberculosis, and the new genetics (1993) (55)
The carboxy‐terminal C2‐like domain of the α‐toxin from Clostridium perfringens mediates calcium‐dependent membrane recognition (1997) (55)
Nucleotide sequence of the aroP gene encoding the general aromatic amino acid transport protein of Escherichia coli K-12: homology with yeast transport proteins. (1990) (54)
Nucleotide sequence and comparative analysis of the frd operon encoding the fumarate reductase of Proteus vulgaris. Extensive sequence divergence of the membrane anchors and absence of an frd-linked ampC cephalosporinase gene. (1987) (54)
Proteome Analysis of the Plasma Membrane of Mycobacterium Tuberculosis (2002) (53)
Towards an immunodiagnostic test for leprosy. (2006) (53)
Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens (1996) (53)
Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer. (2006) (53)
Comparative genomics of the leprosy and tubercle bacilli. (2000) (52)
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis (2015) (52)
Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene. (2000) (51)
Pneumonitis caused by gold salt therapy: evidence for the role of cell-mediated immunity in its pathogenesis. (1980) (51)
Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents. (2006) (51)
Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans. (2003) (51)
In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis (2014) (50)
Evidence for a small anion‐selective channel in the cell wall of Mycobacterium bovis BCG besides a wide cation‐selective pore (1999) (50)
MycDB: an integrated mycobacterial database (1994) (49)
Apparent bacteriophage-binding region of an Escherichia coli K-12 outer membrane protein (1983) (49)
Homing events in the gyrA gene of some mycobacteria. (1996) (49)
The nucleotide sequence of the malT gene encoding the positive regulator of the Escherichia coli maltose regulon. (1986) (49)
Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia (2009) (48)
Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues. (2007) (48)
Clostridium perfringens urease genes are plasmid borne (1997) (48)
Identification and molecular genetic analysis of replication functions of the bacteriocinogenic plasmid pIP404 from Clostridium perfringens. (1988) (48)
Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence (2013) (48)
A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains (2012) (48)
Isolation and characterization of isoniazid-resistant mutants of Mycobacterium smegmatis and M. aurum. (1992) (46)
Case of Diffuse Lepromatous Leprosy Associated with “Mycobacterium lepromatosis” (2011) (46)
Application of Broad-Spectrum Resequencing Microarray for Genotyping Rhabdoviruses (2010) (46)
Rapid expansion of the physical and genetic map of the chromosome of Clostridium perfringens CPN50 (1995) (46)
Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase (2017) (45)
Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital (2013) (44)
TB--A New Target, a New Drug (2005) (44)
Molecular characterization of the resolvase gene, res, carried by a multicopy plasmid from Clostridium perfringens: common evolutionary origin for prokaryotic site‐specific recombinases (1987) (44)
Comparative Analysis of B- and T-Cell Epitopes of Mycobacterium leprae and Mycobacterium tuberculosis Culture Filtrate Protein 10 (2004) (44)
Mycobacterium tuberculosis in the post-genomic age. (2001) (44)
Molecular characterisation of the colicin E2 operon and identification of its products (2004) (44)
High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis (2012) (44)
Molecular genetic analysis of cephalosporinase production and its role in beta-lactam resistance in clinical isolates of Enterobacter cloacae (1987) (43)
Cloning and expression in Escherichia coli K-12 of the genes for major outer membrane protein OmpA from Shigella dysenteriae, Enterobacter aerogenes, and Serratia marcescens (1982) (43)
Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis (2012) (43)
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis (2018) (43)
Inhibiting Mycobacterium tuberculosis within and without (2016) (42)
High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum. (2013) (42)
Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhibitors. (2017) (41)
Transcriptional regulation of lipid homeostasis in mycobacteria (2010) (41)
Massively parallel pathogen identification using high‐density microarrays (2007) (41)
Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities (1989) (40)
Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme (2012) (40)
Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis. (2015) (39)
The Mycobacterium leprae genome: systematic sequence analysis identifies key catabolic enzymes, ATP‐dependent transport systems and a novel polA locus associated with genomic variability (1995) (38)
Drug resistance in Mycobacterium tuberculosis. (1995) (38)
Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides (2007) (38)
Multiplex sequencing of 1.5 Mb of the Mycobacterium leprae genome. (1997) (37)
Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169) (2018) (37)
Are Variable-Number Tandem Repeats Appropriate for Genotyping Mycobacterium leprae? (2008) (36)
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In vitro and in vivo activity of three oxazolidinones 1 against non-replicating Mycobacterium tuberculosis 2 3 4 (2014) (0)
The current state of drug resistance in infectious diseases (2014) (0)
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK (2018) (0)
benzothiazinones against Mycobacterium tuberculosis (2015) (0)
The current state of drug resistance in infectious diseases (2014) (0)
BIOL 5-New medicines for tuberculosis (NM4TB) (2008) (0)
derived from papillomavirus genomic DNA sequences in vitro, their use for diagnostic purposes (1987) (0)
Sequence deleted in M. bovis bcg / m.ou M. tuberculosis, DETECTION METHOD mycobacteria using these sequences and vaccines (1999) (0)
Research letterIdentification of a region of the enterobacterial OmpA protein used as a bacteriocin receptor (1986) (0)
the causative agent of Buruli ulcer Mycobacterium ulcerans of evolution and niche adaptation inferred from the genome (2007) (0)
Specifically, from the genome of Mycobacterium tuberculosis deleted sequences and their use in diagnostics and as vaccines (2002) (0)

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