Stewart Shuman
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Stewart Shuman's Degrees
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Stewart Shuman's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of microRNAs of the herpesvirus family (2005) (1229)
- 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. (1997) (561)
- Dynamic association of capping enzymes with transcribing RNA polymerase II. (2000) (422)
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA (2013) (402)
- What messenger RNA capping tells us about eukaryotic evolution (2002) (332)
- Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme. (1999) (325)
- Active disruption of an RNA-protein interaction by a DExH/D RNA helicase. (2001) (310)
- Structure, mechanism, and evolution of the mRNA capping apparatus. (2001) (307)
- Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB (2005) (305)
- Bacterial DNA repair by non-homologous end joining (2007) (271)
- X-Ray Crystallography Reveals a Large Conformational Change during Guanyl Transfer by mRNA Capping Enzymes (1997) (243)
- Novel approach to molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase. (1994) (243)
- Conservation of Structure and Mechanism between Eukaryotic Topoisomerase I and Site-Specific Recombinases (1998) (232)
- Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II. (2003) (217)
- Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C (2005) (213)
- RNA capping enzyme and DNA ligase: a superfamily of covalent nucleotidyl transferases (1995) (211)
- Crucial roles for DNA ligase III in mitochondria but not in XRCC1-dependent repair (2011) (206)
- The DExH protein NPH-II is a processive and directional motor for unwinding RNA (2000) (194)
- The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases. (2004) (166)
- Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme (2002) (162)
- Catalytic mechanism of DNA topoisomerase IB. (2000) (154)
- Bacteriophage T4 RNA ligase 2 (gp24.1) exemplifies a family of RNA ligases found in all phylogenetic domains (2002) (154)
- Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective (2010) (150)
- Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining. (2000) (149)
- Biochemical and Genetic Analysis of the Four DNA Ligases of Mycobacteria* (2004) (147)
- Three RNA Polymerase II Carboxyl-terminal Domain Kinases Display Distinct Substrate Preferences* (2001) (146)
- Structure and mechanism of mRNA cap (guanine-N7) methyltransferase. (2004) (145)
- Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I. (1997) (145)
- DNA Ligases: Progress and Prospects* (2009) (143)
- Capping enzyme in eukaryotic mRNA synthesis. (1995) (142)
- Interactions between Fission Yeast mRNA Capping Enzymes and Elongation Factor Spt5* (2002) (142)
- The Guanylyltransferase Domain of Mammalian mRNA Capping Enzyme Binds to the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II* (1998) (139)
- Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway (2014) (137)
- Structure and Mechanism of Yeast RNA Triphosphatase An Essential Component of the mRNA Capping Apparatus (1999) (135)
- Tat stimulates cotranscriptional capping of HIV mRNA. (2002) (135)
- Structure and mechanism of RNA ligase. (2004) (133)
- Mechanism of mRNA capping by vaccinia virus guanylyltransferase: characterization of an enzyme--guanylate intermediate. (1981) (130)
- Deciphering the RNA polymerase II CTD code in fission yeast. (2011) (130)
- RtcB Is the RNA Ligase Component of an Escherichia coli RNA Repair Operon* (2011) (127)
- Identification of a vaccinia virus gene encoding a type I DNA topoisomerase. (1987) (121)
- Domain Structure and Mutational Analysis of T4 Polynucleotide Kinase* (2001) (118)
- Purification and characterization of a transcription termination factor from vaccinia virions. (1987) (118)
- Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme. (1998) (116)
- The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends. (2008) (112)
- Characterization of vaccinia virus DNA topoisomerase I expressed in Escherichia coli. (1988) (111)
- Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene (1995) (111)
- Characterization of the CTD Phosphatase Fcp1 from Fission Yeast (2002) (109)
- Specific DNA cleavage and binding by vaccinia virus DNA topoisomerase I. (1990) (108)
- Phylogeny of mRNA capping enzymes. (1997) (107)
- Vaccinia virus RNA helicase: an essential enzyme related to the DE-H family of RNA-dependent NTPases. (1992) (105)
- Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases. (2004) (104)
- Purification of a factor required for transcription of vaccinia virus early genes. (1988) (103)
- Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases. (1994) (98)
- Recombination mediated by vaccinia virus DNA topoisomerase I in Escherichia coli is sequence specific. (1991) (98)
- Mycobacteria exploit three genetically distinct DNA double‐strand break repair pathways (2011) (97)
- Vaccinia virus DNA ligase: specificity, fidelity, and inhibition. (1995) (97)
- Mycobacterial Nonhomologous End Joining Mediates Mutagenic Repair of Chromosomal Double-Strand DNA Breaks (2007) (97)
- Structural insights to how mammalian capping enzyme reads the CTD code. (2011) (96)
- Vaccinia virus DNA topoisomerase: a model eukaryotic type IB enzyme. (1998) (92)
- Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells (2017) (91)
- Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme (2001) (90)
- Intrinsic RNA (guanine-7) methyltransferase activity of the vaccinia virus capping enzyme D1 subunit is stimulated by the D12 subunit. Identification of amino acid residues in the D1 protein required for subunit association and methyl group transfer. (1994) (87)
- Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase (1995) (85)
- Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate. (2007) (85)
- RNA ligase RtcB splices 3′-phosphate and 5′-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3′)pp(5′)G intermediates (2012) (85)
- AdnAB: a new DSB-resecting motor-nuclease from mycobacteria. (2009) (84)
- The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. (2008) (83)
- Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. (1994) (83)
- RtcB, a Novel RNA Ligase, Can Catalyze tRNA Splicing and HAC1 mRNA Splicing in Vivo* (2011) (83)
- A poxvirus-like type IB topoisomerase family in bacteria (2002) (83)
- Interactions between Fission Yeast Cdk9, Its Cyclin Partner Pch1, and mRNA Capping Enzyme Pct1 Suggest an Elongation Checkpoint for mRNA Quality Control* (2003) (82)
- Catalytic activity of vaccinia mRNA capping enzyme subunits coexpressed in Escherichia coli. (1990) (81)
- A freeze-frame view of eukaryotic transcription during elongation and capping of nascent mRNA. (1992) (81)
- How an RNA ligase discriminates RNA versus DNA damage. (2004) (81)
- Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase (2016) (81)
- RNA Substrate Specificity and Structure-guided Mutational Analysis of Bacteriophage T4 RNA Ligase 2* (2004) (81)
- Purification and characterization of a GTP-pyrophosphate exchange activity from vaccinia virions. Association of the GTP-pyrophosphate exchange activity with vaccinia mRNA guanylyltransferase . RNA (guanine-7-)methyltransferase complex (capping enzyme). (1980) (80)
- Mutational analysis of Chlorella virus DNA ligase: catalytic roles of domain I and motif VI. (1998) (80)
- A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II. (2004) (80)
- RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward (2006) (78)
- Characterization of Human, Schizosaccharomyces pombe, and Candida albicans mRNA Cap Methyltransferases and Complete Replacement of the Yeast Capping Apparatus by Mammalian Enzymes* (1999) (78)
- Characterization of an ATP-dependent DNA ligase encoded by Chlorella virus PBCV-1 (1997) (78)
- Novel Mechanism of RNA Repair by RtcB via Sequential 2′,3′-Cyclic Phosphodiesterase and 3′-Phosphate/5′-Hydroxyl Ligation Reactions* (2011) (78)
- Vaccinia virus morphogenesis is blocked by temperature-sensitive mutations in the F10 gene, which encodes protein kinase 2 (1995) (77)
- Yeast and Viral RNA 5′ Triphosphatases Comprise a New Nucleoside Triphosphatase Family* (1998) (76)
- RNA repair: an antidote to cytotoxic eukaryal RNA damage. (2008) (75)
- RNA 5′-Triphosphatase, Nucleoside Triphosphatase, and Guanylyltransferase Activities of Baculovirus LEF-4 Protein (1998) (75)
- Factor-dependent transcription termination by vaccinia virus RNA polymerase. Evidence that the cis-acting termination signal is in nascent RNA. (1988) (74)
- The Length, Phosphorylation State, and Primary Structure of the RNA Polymerase II Carboxyl-terminal Domain Dictate Interactions with mRNA Capping Enzymes* (2001) (72)
- Mutational analysis of the Saccharomyces cerevisiae ABD1 gene: cap methyltransferase activity is essential for cell growth (1996) (71)
- Genetic, Physical, and Functional Interactions between the Triphosphatase and Guanylyltransferase Components of the Yeast mRNA Capping Apparatus (1998) (71)
- Structural basis for nick recognition by a minimal pluripotent DNA ligase (2007) (70)
- Structure-Function Analysis of T4 RNA Ligase 2* (2003) (70)
- Mycobacterial UvrD1 Is a Ku-dependent DNA Helicase That Plays a Role in Multiple DNA Repair Events, Including Double-strand Break Repair* (2007) (69)
- Genetic and Biochemical Analysis of the Functional Domains of Yeast tRNA Ligase* (2003) (69)
- Covalent catalysis in nucleotidyl transfer. A KTDG motif essential for enzyme-GMP complex formation by mRNA capping enzyme is conserved at the active sites of RNA and DNA ligases. (1993) (69)
- Separable Functions of the Fission Yeast Spt5 Carboxyl-Terminal Domain (CTD) in Capping Enzyme Binding and Transcription Elongation Overlap with Those of the RNA Polymerase II CTD (2010) (68)
- The QRxGRxGRxxxG motif of the vaccinia virus DExH box RNA helicase NPH-II is required for ATP hydrolysis and RNA unwinding but not for RNA binding (1996) (68)
- Purification and properties of vaccinia virus DNA-dependent RNA polymerase. (1980) (68)
- Crystal Structure and Nonhomologous End-joining Function of the Ligase Component of Mycobacterium DNA Ligase D* (2006) (68)
- Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination. (1998) (68)
- Conditional inactivation of mRNA capping enzyme affects yeast pre-mRNA splicing in vivo. (1996) (67)
- Specificity and fidelity of strand joining by Chlorella virus DNA ligase. (1998) (67)
- Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component (1993) (67)
- Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D. (2006) (66)
- Vaccinia virus gene D12L encodes the small subunit of the viral mRNA capping enzyme. (1989) (66)
- Chlorella virus DNA ligase: nick recognition and mutational analysis. (1998) (66)
- A Primer-dependent Polymerase Function of Pseudomonas aeruginosa ATP-dependent DNA Ligase (LigD)* (2005) (65)
- Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase. (2002) (65)
- Mutational analysis of Escherichia coli DNA ligase identifies amino acids required for nick-ligation in vitro and for in vivo complementation of the growth of yeast cells deleted for CDC9 and LIG4. (1999) (64)
- Identification of Novel Antipoxviral Agents: Mitoxantrone Inhibits Vaccinia Virus Replication by Blocking Virion Assembly (2007) (64)
- Characterization of the Schizosaccharomyces pombe Cdk9/Pch1 Protein Kinase (2003) (63)
- Novel 3′-Ribonuclease and 3′-Phosphatase Activities of the Bacterial Non-homologous End-joining Protein, DNA Ligase D* (2005) (63)
- Site-specific interaction of vaccinia virus topoisomerase I with duplex DNA. Minimal DNA substrate for strand cleavage in vitro. (1991) (63)
- HIV-1 Tat Protein Interacts with Mammalian Capping Enzyme and Stimulates Capping of TAR RNA* (2001) (62)
- Resolution of Holliday junctions by eukaryotic DNA topoisomerase I. (1996) (62)
- Characterization of an ATP-dependent DNA ligase from the thermophilic archaeon Methanobacterium thermoautotrophicum. (2000) (62)
- Characterization of ts 16, a temperature-sensitive mutant of vaccinia virus (1995) (62)
- Expression and characterization of an RNA capping enzyme encoded by Chlorella virus PBCV-1 (1996) (62)
- DNA strand transfer reactions catalyzed by vaccinia topoisomerase I. (1992) (61)
- Portability and fidelity of RNA-repair systems. (2004) (61)
- Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167. (1997) (60)
- Proton Relay Mechanism of General Acid Catalysis by DNA Topoisomerase IB* (2002) (59)
- Vaccinia Virus Infection Attenuates Innate Immune Responses and Antigen Presentation by Epidermal Dendritic Cells (2006) (58)
- Structure-Function Analysis of the mRNA Cap Methyltransferase of Saccharomyces cerevisiae * (1997) (57)
- NAD+-dependent DNA Ligase Encoded by a Eukaryotic Virus* (2001) (57)
- Site-specific DNA cleavage by vaccinia virus DNA topoisomerase I. Role of nucleotide sequence and DNA secondary structure. (1991) (57)
- Mutational analysis of yeast mRNA capping enzyme. (1994) (57)
- The Nucleoside Triphosphatase and Helicase Activities of Vaccinia Virus NPH-II Are Essential for Virus Replication (1998) (57)
- Bacterial Nonhomologous End Joining Ligases Preferentially Seal Breaks with a 3′-OH Monoribonucleotide* (2008) (57)
- Structure–function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase (2005) (56)
- Mechanism of RNA 2′,3′-cyclic phosphate end healing by T4 polynucleotide kinase–phosphatase (2012) (55)
- Structure-function analysis of yeast mRNA cap methyltransferase and high-copy suppression of conditional mutants by AdoMet synthase and the ubiquitin conjugating enzyme Cdc34p. (2000) (55)
- Mutational analysis of mRNA capping enzyme identifies amino acids involved in GTP binding, enzyme-guanylate formation, and GMP transfer to RNA (1995) (55)
- Origins of mRNA identity: capping enzymes bind to the phosphorylated C-terminal domain of RNA polymerase II. (1997) (54)
- Cyclin-Dependent Kinase 9 (Cdk9) of Fission Yeast Is Activated by the CDK-Activating Kinase Csk1, Overlaps Functionally with the TFIIH-Associated Kinase Mcs6, and Associates with the mRNA Cap Methyltransferase Pcm1 In Vivo (2006) (54)
- Characterization of an ATP-dependent DNA ligase encoded by Haemophilus influenzae. (1997) (54)
- Stereochemical outcome and kinetic effects of Rp- and Sp-phosphorothioate substitutions at the cleavage site of vaccinia type I DNA topoisomerase. (2000) (53)
- Vaccinia DNA topoisomerase I promotes illegitimate recombination in Escherichia coli. (1989) (53)
- Structure of a CRISPR-associated protein Cas2 from Desulfovibrio vulgaris. (2010) (53)
- Footprinting of Chlorella Virus DNA Ligase Bound at a Nick in Duplex DNA* (1999) (52)
- Mutational analysis of vaccinia DNA ligase defines residues essential for covalent catalysis. (1995) (52)
- Genetic and Biochemical Analysis of Yeast and Human Cap Trimethylguanosine Synthase (2008) (51)
- Two classes of DNA end-joining reactions catalyzed by vaccinia topoisomerase I. (1992) (51)
- Different Strategies for Carboxyl-terminal Domain (CTD) Recognition by Serine 5-specific CTD Phosphatases* (2005) (50)
- Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I. (1989) (49)
- A Phosphate-binding Histidine of Binuclear Metallophosphodiesterase Enzymes Is a Determinant of 2′,3′-Cyclic Nucleotide Phosphodiesterase Activity* (2008) (49)
- Structure-function analysis of yeast tRNA ligase. (2005) (49)
- Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo. (2008) (49)
- Mutational analysis of the vaccinia virus E3 protein defines amino acid residues involved in E3 binding to double-stranded RNA (1996) (48)
- Mutational Analysis of 39 Residues of Vaccinia DNA Topoisomerase Identifies Lys-220, Arg-223, and Asn-228 as Important for Covalent Catalysis* (1997) (48)
- Vaccinia topoisomerase binds circumferentially to DNA. (1994) (48)
- Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing. (1998) (48)
- Histidine 265 Is Important for Covalent Catalysis by Vaccinia Topoisomerase and Is Conserved in All Eukaryotic Type I Enzymes* (1997) (48)
- Conserved Residues in Domain Ia Are Required for the Reaction of Escherichia coli DNA Ligase with NAD+ * (2002) (48)
- Physical and functional characterization of the double-stranded RNA binding protein encoded by the vaccinia virus E3 gene. (1996) (48)
- Nascent RNA cleavage by purified ternary complexes of vaccinia RNA polymerase. (1993) (47)
- Identification of contacts between topoisomerase I and its target DNA by site‐specific photocrosslinking. (1996) (47)
- Structure–function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog (2006) (47)
- Mutational Analysis of Bacteriophage T4 RNA Ligase 1 (2003) (47)
- Punctuation and syntax of the RNA polymerase II CTD code in fission yeast (2012) (47)
- Vaccinia virus RNA helicase. Directionality and substrate specificity. (1993) (47)
- Domain requirements for DNA unwinding by mycobacterial UvrD2, an essential DNA helicase. (2008) (46)
- The sequential 2′,3′-cyclic phosphodiesterase and 3′-phosphate/5′-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependent (2012) (45)
- Vaccinia Virus Subverts a Mitochondrial Antiviral Signaling Protein-Dependent Innate Immune Response in Keratinocytes through Its Double-Stranded RNA Binding Protein, E3 (2008) (45)
- Factor-dependent transcription termination by vaccinia RNA polymerase. Kinetic coupling and requirement for ATP hydrolysis. (1994) (44)
- Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I. (1992) (44)
- Characterization of Schizosaccharomyces pombe RNA triphosphatase. (2001) (44)
- Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast (2016) (43)
- Characterization of a Baculovirus-Encoded RNA 5′-Triphosphatase (1998) (43)
- Characterization of Agrobacterium tumefaciens DNA ligases C and D (2007) (43)
- Specificity and Mechanism of RNA Cap Guanine-N2 Methyltransferase (Tgs1)* (2005) (43)
- Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast (2014) (43)
- Mutational analysis of the RNA triphosphatase component of vaccinia virus mRNA capping enzyme (1996) (43)
- Structure-Function Analysis of the Active Site Tunnel of Yeast RNA Triphosphatase* (2001) (43)
- Methyltransferase and subunit association domains of vaccinia virus mRNA capping enzyme. (1992) (42)
- Mutational Analyses of Yeast RNA Triphosphatases Highlight a Common Mechanism of Metal-dependent NTP Hydrolysis and a Means of Targeting Enzymes to Pre-mRNAs in Vivo by Fusion to the Guanylyltransferase Component of the Capping Apparatus* (1999) (42)
- Temperature-sensitive mutations in the vaccinia virus H4 gene encoding a component of the virion RNA polymerase (1992) (41)
- Crystal structure of vaccinia virus mRNA capping enzyme provides insights into the mechanism and evolution of the capping apparatus. (2014) (41)
- An end-healing enzyme from Clostridium thermocellum with 5' kinase, 2',3' phosphatase, and adenylyltransferase activities. (2005) (41)
- A Conserved Domain of Yeast RNA Triphosphatase Flanking the Catalytic Core Regulates Self-association and Interaction with the Guanylyltransferase Component of the mRNA Capping Apparatus* (1999) (41)
- Insertional mutagenesis of the vaccinia virus gene encoding a type I DNA topoisomerase: evidence that the gene is essential for virus growth. (1989) (41)
- Role of nucleotidyltransferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase. (2002) (41)
- The PAF Complex and Prf1/Rtf1 Delineate Distinct Cdk9-Dependent Pathways Regulating Transcription Elongation in Fission Yeast (2013) (41)
- The D1 and D12 subunits are both essential for the transcription termination factor activity of vaccinia virus capping enzyme (1995) (41)
- Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domain. (2008) (40)
- Characterization of Mimivirus DNA Topoisomerase IB Suggests Horizontal Gene Transfer between Eukaryal Viruses and Bacteria (2006) (40)
- Mammalian 2',3' cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo. (2007) (40)
- Peptide inhibitors of DNA cleavage by tyrosine recombinases and topoisomerases. (2000) (39)
- A yeast-like mRNA capping apparatus in Plasmodium falciparum (2001) (39)
- Characterization of a Thermophilic ATP-Dependent DNA Ligase from the Euryarchaeon Pyrococcus horikoshii (2005) (39)
- Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway (2011) (39)
- Characterization of a Baculovirus Enzyme with RNA Ligase, Polynucleotide 5′-Kinase, and Polynucleotide 3′-Phosphatase Activities* (2004) (39)
- Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription (1996) (39)
- Essential Constituents of the 3′-Phosphoesterase Domain of Bacterial DNA Ligase D, a Nonhomologous End-joining Enzyme* (2005) (38)
- Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme (1997) (38)
- Gap Filling Activities of Pseudomonas DNA Ligase D (LigD) Polymerase and Functional Interactions of LigD with the DNA End-binding Ku Protein* (2009) (38)
- Characterization of Candida albicans RNA triphosphatase and mutational analysis of its active site. (2000) (38)
- The mRNA capping apparatus as drug target and guide to eukaryotic phylogeny. (2001) (38)
- How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes (2014) (37)
- A second NAD(+)-dependent DNA ligase (LigB) in Escherichia coli. (2001) (37)
- Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step. (1994) (37)
- Site-specific interaction of vaccinia virus topoisomerase I with base and sugar moieties in duplex DNA. (1993) (37)
- Recombinogenic Flap Ligation Pathway for Intrinsic Repair of Topoisomerase IB-Induced Double-Strand Breaks (2000) (36)
- Proteolytic footprinting of vaccinia topoisomerase bound to DNA (1995) (36)
- Nick sensing by vaccinia virus DNA ligase requires a 5' phosphate at the nick and occupancy of the adenylate binding site on the enzyme (1997) (36)
- Characterization of the mRNA Capping Apparatus of the Microsporidian Parasite Encephalitozoon cuniculi * (2002) (36)
- An essential surface motif (WAQKW) of yeast RNA triphosphatase mediates formation of the mRNA capping enzyme complex with RNA guanylyltransferase. (1999) (36)
- Bromouridine triphosphate inhibits transcription termination and mRNA release by vaccinia virions. (1989) (36)
- Characterization of the Mycobacterial AdnAB DNA Motor Provides Insights into the Evolution of Bacterial Motor-Nuclease Machines* (2009) (35)
- A role for the H4 subunit of vaccinia RNA polymerase in transcription initiation at a viral early promoter. (1994) (35)
- The role of ATP in in vitro vaccinia virus RNA synthesis effects of AMP-PNP and ATP gamma S. (1980) (35)
- Guarding the genome: electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB. (2003) (34)
- Discrete functional stages of vaccinia virus early transcription during a single round of RNA synthesis in vitro. (1991) (34)
- Mutational analysis of the guanylyltransferase component of Mammalian mRNA capping enzyme. (2003) (34)
- Substrate Specificity and Structure-Function Analysis of the 3′-Phosphoesterase Component of the Bacterial NHEJ Protein, DNA Ligase D* (2006) (34)
- Mutational analysis of Mycobacterium UvrD1 identifies functional groups required for ATP hydrolysis, DNA unwinding, and chemomechanical coupling. (2009) (33)
- Nucleotide Misincorporation, 3′-Mismatch Extension, and Responses to Abasic Sites and DNA Adducts by the Polymerase Component of Bacterial DNA Ligase D* (2006) (33)
- Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD. (2005) (33)
- Encephalitozoon cuniculi mRNA Cap (Guanine N-7) Methyltransferase (2005) (33)
- Role of Nucleotidyl Transferase Motif V in Strand Joining byChlorella Virus DNA Ligase* (2002) (33)
- 2′-Phosphate cyclase activity of RtcA: a potential rationale for the operon organization of RtcA with an RNA repair ligase RtcB in Escherichia coli and other bacterial taxa (2013) (33)
- Rewriting the rules for end joining via enzymatic splicing of DNA 3′-PO4 and 5′-OH ends (2013) (32)
- Yeast-like mRNA Capping Apparatus in Giardia lamblia* (2005) (32)
- Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins. (2006) (32)
- Structure of bacterial LigD 3′-phosphoesterase unveils a DNA repair superfamily (2010) (32)
- Vaccinia virus mRNA (guanine-7-)methyltransferase: mutational effects on cap methylation and AdoHcy-dependent photo-cross-linking of the cap to the methyl acceptor site. (1996) (32)
- Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation (2014) (32)
- Schizosaccharomyces pombe Carboxyl-terminal Domain (CTD) Phosphatase Fcp1 (2004) (32)
- Vaccinia virus RNA helicase: nucleic acid specificity in duplex unwinding (1996) (31)
- Innate Immune Response of Human Plasmacytoid Dendritic Cells to Poxvirus Infection Is Subverted by Vaccinia E3 via Its Z-DNA/RNA Binding Domain (2012) (31)
- Mechanism of Inhibition of Vaccinia DNA Topoisomerase by Novobiocin and Coumermycin (*) (1996) (31)
- Characterization of the 2′,3′ cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage λ phosphatase (2007) (31)
- RNA Triphosphatase Component of the mRNA Capping Apparatus of Paramecium bursaria Chlorella Virus 1 (2001) (31)
- An RNA Ligase from Deinococcus radiodurans* (2004) (31)
- Mycobacterium smegmatis DinB2 misincorporates deoxyribonucleotides and ribonucleotides during templated synthesis and lesion bypass (2014) (31)
- Analysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediate. (2003) (31)
- Double Strand Break Unwinding and Resection by the Mycobacterial Helicase-Nuclease AdnAB in the Presence of Single Strand DNA-binding Protein (SSB)* (2010) (30)
- Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. (2010) (30)
- Giardia lamblia RNA Cap Guanine-N2 Methyltransferase (Tgs2)* (2005) (30)
- Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells (2011) (30)
- Distinct Enzymic Functional Groups Are Required for the Phosphomonoesterase and Phosphodiesterase Activities of Clostridium thermocellum Polynucleotide Kinase/Phosphatase* (2006) (30)
- Domain structure of vaccinia DNA ligase. (1997) (30)
- Domain structure of vaccinia virus mRNA capping enzyme. Activity of the Mr 95,000 subunit expressed in Escherichia coli. (1990) (30)
- Factor-dependent Release of Nascent RNA by Ternary Complexes of Vaccinia RNA Polymerase* (1996) (30)
- A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing (2013) (30)
- Mutational Analysis of Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity* (2006) (30)
- Functional domains of vaccinia virus mRNA capping enzyme. Analysis by limited tryptic digestion. (1989) (29)
- Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB. (2004) (29)
- A kinetic framework for tRNA ligase and enforcement of a 2'-phosphate requirement for ligation highlights the design logic of an RNA repair machine. (2013) (29)
- A Yeast-Based Genetic System for Functional Analysis of Viral mRNA Capping Enzymes (2000) (29)
- NAD+-dependent synthesis of a 5′-phospho-ADP-ribosylated RNA/DNA cap by RNA 2′-phosphotransferase Tpt1 (2018) (29)
- Characterization of the mRNA Capping Apparatus of Candida albicans * (2001) (29)
- Characterization of mimivirus NAD+-dependent DNA ligase. (2006) (29)
- Characterization of bacteriophage KVP40 and T4 RNA ligase 2. (2004) (29)
- Requirements for noncovalent binding of vaccinia topoisomerase I to duplex DNA. (1994) (28)
- Intramolecular synapsis of duplex DNA by vaccinia topoisomerase (1997) (28)
- A Catalytic Domain of Eukaryotic DNA Topoisomerase I* (1998) (28)
- RNA 3′-Phosphate Cyclase (RtcA) Catalyzes Ligase-like Adenylylation of DNA and RNA 5′-Monophosphate Ends* (2010) (28)
- Mechanistic plasticity of DNA topoisomerase IB: phosphate electrostatics dictate the need for a catalytic arginine. (2005) (28)
- Mutational analysis of vaccinia DNA topoisomerase defines amino acid residues essential for covalent catalysis. (1994) (27)
- Biochemical and genetic analysis of RNA cap guanine-N2 methyltransferases from Giardia lamblia and Schizosaccharomyces pombe (2007) (27)
- Novel Triphosphate Phosphohydrolase Activity of Clostridium thermocellum TTM, a Member of the Triphosphate Tunnel Metalloenzyme Superfamily* (2007) (27)
- Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site. (2010) (27)
- RNA capping by HeLa cell RNA guanylyltransferase. Characterization of a covalent protein-guanylate intermediate. (1982) (27)
- Structure-function analysis of the yeast NAD+-dependent tRNA 2'-phosphotransferase Tpt1. (2005) (27)
- Ligation of RNA-containing duplexes by vaccinia DNA ligase. (1997) (27)
- Crystal Structure of Baculovirus RNA Triphosphatase Complexed with Phosphate* (2005) (27)
- Yeast-Based Genetic System for Functional Analysis of Poxvirus mRNA Cap Methyltransferase (2003) (27)
- Mutational analyses of trimethylguanosine synthase (Tgs1) and Mud2: proteins implicated in pre-mRNA splicing. (2010) (26)
- RNA capping: progress and prospects (2015) (26)
- Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium. (1996) (26)
- RNA polymerase II CTD phospho-sites Ser5 and Ser7 govern phosphate homeostasis in fission yeast (2015) (26)
- Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase. (2006) (26)
- The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair. (2007) (26)
- Characterization of a thermostable archaeal polynucleotide kinase homologous to human Clp1. (2009) (26)
- Characterization of Polynucleotide Kinase/Phosphatase Enzymes from Mycobacteriophages Omega and Cjw1 and Vibriophage KVP40* (2004) (26)
- Phenotypic selection and characterization of mutant alleles of a eukaryotic DNA topoisomerase I. (1990) (25)
- Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme (2007) (25)
- Mechanism of Phosphoanhydride Cleavage by Baculovirus Phosphatase* (2000) (25)
- Structure-Function Analysis of Trypanosoma brucei RNA Triphosphatase and Evidence for a Two-metal Mechanism* (2003) (25)
- Dual Mechanisms whereby a Broken RNA End Assists the Catalysis of Its Repair by T4 RNA Ligase 2* (2005) (25)
- Determinants of Nam8-dependent splicing of meiotic pre-mRNAs (2011) (24)
- Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: an essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA. (2012) (24)
- RNA polymerase II CTD interactome with 3′ processing and termination factors in fission yeast and its impact on phosphate homeostasis (2018) (24)
- An ATPase Component of the Transcription Elongation Complex Is Required for Factor-dependent Transcription Termination by Vaccinia RNA Polymerase* (1996) (24)
- 5'-Hydroxyl polyribonucleotide kinase from HeLa cell nuclei. Purification and properties. (1979) (24)
- Crystal Structure of a Bacterial Type IB DNA Topoisomerase Reveals a Preassembled Active Site in the Absence of DNA* (2006) (24)
- Structure-guided mutational analysis of T4 RNA ligase 1. (2006) (24)
- Mapping the triphosphatase active site of baculovirus mRNA capping enzyme LEF4 and evidence for a two-metal mechanism. (2003) (24)
- Characterization of Mycobacterium smegmatis PolD2 and PolD1 as RNA/DNA polymerases homologous to the POL domain of bacterial DNA ligase D. (2012) (24)
- Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase (2015) (23)
- A long noncoding (lnc)RNA governs expression of the phosphate transporter Pho84 in fission yeast and has cascading effects on the flanking prt lncRNA and pho1 genes (2018) (23)
- Mycobacterium smegmatis Lhr Is a DNA-dependent ATPase and a 3′-to-5′ DNA Translocase and Helicase That Prefers to Unwind 3′-Tailed RNA:DNA Hybrids* (2013) (23)
- Defining the Active Site of Schizosaccharomyces pombeC-terminal Domain Phosphatase Fcp1* (2003) (23)
- Structural analysis of ternary complexes of vaccinia RNA polymerase. (1992) (23)
- Structure–function analysis and genetic interactions of the yeast branchpoint binding protein Msl5 (2012) (22)
- Transcriptional interference at tandem lncRNA and protein-coding genes: an emerging theme in regulation of cellular nutrient homeostasis (2020) (22)
- Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion (2005) (22)
- Effects of deletion mutations in the yeast Ces1 protein on cell growth and morphology and on high copy suppression of mutations in mRNA capping enzyme and translation initiation factor 4A. (1998) (22)
- Polynucleotide ligase activity of eukaryotic topoisomerase I. (1998) (22)
- Poly(A) site choice and Pol2 CTD Serine-5 status govern lncRNA control of phosphate-responsive tgp1 gene expression in fission yeast (2018) (22)
- Mutational Analysis of Baculovirus Capping Enzyme Lef4 Delineates an Autonomous Triphosphatase Domain and Structural Determinants of Divalent Cation Specificity* (2001) (22)
- Purification and use of vaccinia virus messenger RNA capping enzyme. (1990) (22)
- Vaccinia topoisomerase and Cre recombinase catalyze direct ligation of activated DNA substrates containing a 3'-para-nitrophenyl phosphate ester. (2000) (22)
- A proposed mechanism of mRNA synthesis and capping by vesicular stomatitis virus. (1997) (22)
- Characterization of a mimivirus RNA cap guanine-N2 methyltransferase. (2009) (22)
- Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer. (2010) (22)
- Covalent DNA Binding by Vaccinia Topoisomerase Results in Unpairing of the Thymine Base 5′ of the Scissile Bond* (1996) (22)
- The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family (2012) (21)
- Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase. (2007) (21)
- Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28 (2014) (21)
- Dynamics of phosphodiester synthesis by DNA ligase (2008) (21)
- An essential role for trimethylguanosine RNA caps in Saccharomyces cerevisiae meiosis and their requirement for splicing of SAE3 and PCH2 meiotic pre-mRNAs (2011) (20)
- Kinetic Analysis of DNA and RNA Strand Transfer Reactions Catalyzed by Vaccinia Topoisomerase* (1997) (20)
- RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA (2019) (20)
- Closing the gap on DNA ligase. (1996) (20)
- Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease. (2009) (20)
- Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3′ processing and transcription termination (2019) (20)
- Vaccinia virus poly(A) polymerase. Specificity for nucleotides and nucleotide analogs. (1988) (20)
- Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli NAD+-dependent DNA Ligase (LigA)* (2005) (20)
- Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis. (2011) (20)
- Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification (2015) (20)
- Structure-guided Mutational Analysis of the OB, HhH, and BRCT Domains of Escherichia coli DNA Ligase* (2008) (20)
- Defining the DNA Binding Site Recognized by the Fission Yeast Zn2Cys6 Transcription Factor Pho7 and Its Role in Phosphate Homeostasis (2017) (20)
- Characterization of a DNA topoisomerase encoded by Amsacta moore entomopoxvirus. (1997) (20)
- Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3′ to 5′ translocase and helicase activities (2012) (20)
- Novobiocin inhibits vaccinia virus replication by blocking virus assembly. (1997) (20)
- Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding. (1997) (20)
- Chlorella Virus RNA Triphosphatase (2002) (20)
- Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase. (2011) (19)
- Structure and mechanism of E. coli RNA 2′,3′-cyclic phosphodiesterase (2014) (19)
- RNA binding properties of vaccinia virus capping enzyme. (1993) (19)
- Site-specific DNA transesterification by vaccinia topoisomerase: role of specific phosphates and nucleosides. (1999) (19)
- Individual Nucleotide Bases, Not Base Pairs, Are Critical for Triggering Site-specific DNA Cleavage by Vaccinia Topoisomerase* (2004) (19)
- Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease. (1998) (19)
- Distinctive kinetics and substrate specificities of plant and fungal tRNA ligases (2014) (19)
- Adenosine N1-oxide inhibits vaccinia virus replication by blocking translation of viral early mRNAs (1995) (19)
- Structure-activity relationships in human RNA 3'-phosphate cyclase. (2009) (19)
- Mapping the active site of vaccinia virus RNA triphosphatase. (2003) (19)
- Structure–function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP (2016) (18)
- Stimulation of vaccinia topoisomerase I by nucleoside triphosphates. (1994) (18)
- Determinants of eukaryal cell killing by the bacterial ribotoxin PrrC (2010) (18)
- DNA strand transfer reactions catalyzed by vaccinia topoisomerase: hydrolysis and glycerololysis of the covalent protein-DNA intermediate. (1997) (18)
- Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities. (2010) (18)
- Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. (2012) (18)
- An encephalitozoon cuniculi ortholog of the RNA polymerase II carboxyl-terminal domain (CTD) serine phosphatase Fcp1. (2004) (18)
- Structure-Function Analysis of Yeast mRNA Cap Methyltransferase and High-Copy Suppression of Conditional Mutants by AdoMet Synthase and the Ubiquitin Conjugating Enzyme Cdc 34 p (2000) (18)
- Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs (2015) (18)
- RecF and RecR Play Critical Roles in the Homologous Recombination and Single-Strand Annealing Pathways of Mycobacteria (2015) (17)
- Structure–function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1 (2015) (17)
- Homodimeric Quaternary Structure Is Required for the in Vivo Function and Thermal Stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA Triphosphatases* (2003) (17)
- Impact of DNA3′pp5′G capping on repair reactions at DNA 3′ ends (2014) (17)
- Trypanosoma brucei RNA Triphosphatase (2001) (17)
- Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD+-dependent DNA ligase (LigA) (2016) (16)
- Chemical and Traditional Mutagenesis of Vaccinia DNA Topoisomerase Provides Insights to Cleavage Site Recognition and Transesterification Chemistry* (2008) (16)
- Benzo[a]pyrene-dG Adduct Interference Illuminates the Interface of Vaccinia Topoisomerase with the DNA Minor Groove* (2003) (16)
- Transcriptional Networking Cap-tures the 7SK RNA 5′-γ-Methyltransferase (2007) (16)
- Structure-function analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase. (2008) (16)
- DNA strand transfer catalyzed by vaccinia topoisomerase: peroxidolysis and hydroxylaminolysis of the covalent protein-DNA intermediate. (2000) (16)
- Mutational Analysis of Vaccinia Virus Nucleoside Triphosphate Phosphohydrolase I, a DNA-Dependent ATPase of the DExH Box Family (1999) (16)
- Structure-function analysis of the 5′ end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors (2013) (16)
- Melanoplus sanguinipes entomopoxvirus DNA topoisomerase: site-specific DNA transesterification and effects of 5'-bridging phosphorothiolates. (1999) (16)
- Two-step mechanism and step-arrest mutants of Runella slithyformis NAD+-dependent tRNA 2′-phosphotransferase Tpt1 (2018) (15)
- Polyphosphatase Activity of CthTTM, a Bacterial Triphosphate Tunnel Metalloenzyme* (2008) (15)
- Resolution of a Holliday junction by vaccinia topoisomerase requires a spacer DNA segment 3' of the CCCTT/ cleavage sites. (2000) (15)
- Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP•Mg2+ and 5′-OH oligonucleotide and a product complex with GDP•Mg2+ and 5′-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition (2013) (15)
- Structure and mechanism of the 2′,3′ phosphatase component of the bacterial Pnkp-Hen1 RNA repair system (2013) (15)
- A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair. (2012) (15)
- Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases (2016) (15)
- Multicopy suppressors of temperature-sensitive mutations of yeast mRNA capping enzyme. (1996) (15)
- Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2′-PO4 recognition and ADP-ribosylation (2019) (15)
- Genetic analysis of poxvirus mRNA cap methyltransferase: suppression of conditional mutations in the stimulatory D12 subunit by second-site mutations in the catalytic D1 subunit. (2006) (15)
- Determinants of the cytotoxicity of PrrC anticodon nuclease and its amelioration by tRNA repair. (2012) (14)
- Copper ion binding and enzyme inhibitory properties of the antithyroid drug methimazole (1975) (14)
- Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3′-OH base mispairs and damaged base lesions (2013) (14)
- Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases (2017) (14)
- Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III. (2006) (14)
- Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28 (2014) (14)
- Elongation properties of vaccinia virus RNA polymerase: pausing, slippage, 3' end addition, and termination site choice. (1997) (14)
- Benzo[c]phenanthrene Adducts and Nogalamycin Inhibit DNA Transesterification by Vaccinia Topoisomerase* (2004) (14)
- Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex. (2009) (14)
- RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicans (2001) (14)
- An Essential Function of Saccharomyces cerevisiae RNA Triphosphatase Cet1 Is to Stabilize RNA Guanylyltransferase Ceg1 against Thermal Inactivation* (2001) (14)
- Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination. (2014) (14)
- Stability of ternary transcription complexes of vaccinia virus RNA polymerase at promoter-proximal positions. (1992) (13)
- Characterization of Lhr-Core DNA helicase and manganese- dependent DNA nuclease components of a bacterial gene cluster encoding nucleic acid repair enzymes (2018) (13)
- A temperature-sensitive mutation of the vaccinia virus E11 gene encoding a 15-kDa virion component. (1996) (13)
- Structure-Function Analysis of the OB and Latch Domains of Chlorella Virus DNA Ligase* (2011) (13)
- Effects of 3′-OH and 5′-PO4 Base Mispairs and Damaged Base Lesions on the Fidelity of Nick Sealing by Deinococcus radiodurans RNA Ligase (2014) (13)
- Solution NMR studies of Chlorella virus DNA ligase-adenylate. (2010) (13)
- Importance of Homodimerization for the in Vivo Function of Yeast RNA Triphosphatase* (2001) (13)
- Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site. (2008) (12)
- Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase. (2013) (12)
- Antitermination of vaccinia virus early transcription: possible role of RNA secondary structure. (1991) (12)
- The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans (2018) (12)
- Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates (2019) (12)
- Ternary complex formation by vaccinia virus RNA polymerase at an early viral promoter: analysis by native gel electrophoresis (1992) (12)
- Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3′–5′ translocase and duplex unwinding activities (2012) (12)
- Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection (2019) (12)
- Structures of RNA 3′-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis (2011) (12)
- Deinococcus radiodurans RNA ligase exemplifies a novel ligase clade with a distinctive N-terminal module that is important for 5′-PO4 nick sealing and ligase adenylylation but dispensable for phosphodiester formation at an adenylylated nick (2007) (12)
- Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis (2018) (12)
- Transcription Termination by Vaccinia RNA Polymerase Entails Recognition of Specific Phosphates in the Nascent RNA* (1997) (12)
- Functional Dissection of the DNA Interface of the Nucleotidyltransferase Domain of Chlorella Virus DNA Ligase* (2011) (12)
- Fission yeast RNA triphosphatase reads an Spt5 CTD code (2015) (11)
- Distinct Contributions of Enzymic Functional Groups to the 2′,3′-Cyclic Phosphodiesterase, 3′-Phosphate Guanylylation, and 3′-ppG/5′-OH Ligation Steps of the Escherichia coli RtcB Nucleic Acid Splicing Pathway (2016) (11)
- Structure of mycobacterial 3′-to-5′ RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases (2017) (11)
- Structures and activities of archaeal members of the LigD 3′-phosphoesterase DNA repair enzyme superfamily (2011) (11)
- Characterization of 3′-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5′-Phosphate Capping Activity of RtcB3 (2015) (11)
- Mycobacterium smegmatis HelY Is an RNA-Activated ATPase/dATPase and 3′-to-5′ Helicase That Unwinds 3′-Tailed RNA Duplexes and RNA:DNA Hybrids (2015) (11)
- 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two (2016) (11)
- Semi-artificial Fluorescent Molecular Machine for DNA Damage Detection. (2004) (11)
- Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1 (2015) (11)
- Kinetic Analysis of DNA Strand Joining by Chlorella Virus DNA Ligase and the Role of Nucleotidyltransferase Motif VI in Ligase Adenylylation* (2012) (11)
- Structure-function relations in the NTPase domain of the antiviral tRNA ribotoxin Escherichia coli PrrC. (2012) (11)
- Sinefungin resistance of Saccharomyces cerevisiae arising from sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase (2007) (11)
- Crystallization of the RNA guanylyltransferase of Chlorella virus PBCV-1. (1997) (10)
- Nonpolar Nucleobase Analogs Illuminate Requirements for Site-specific DNA Cleavage by Vaccinia Topoisomerase* (2006) (10)
- Vaccinia Topoisomerase Mutants Illuminate Conformational Changes during Closure of the Protein Clamp and Assembly of a Functional Active Site* (2001) (10)
- Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo (2016) (10)
- Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase (2017) (10)
- Resolution of undistorted symmetric immobile DNA junctions by vaccinia topoisomerase I. (2004) (10)
- Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage. (1997) (10)
- Poxvirus mRNA Cap Methyltransferase (2006) (10)
- Structure–function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring (2016) (10)
- Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkp•hen1 RNA repair system. (2013) (10)
- Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA)* (2009) (10)
- Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi (2015) (10)
- Effect of 2′-5′ Phosphodiesters on DNA Transesterification by Vaccinia Topoisomerase* (2001) (9)
- Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858) (2016) (9)
- Site-specific DNA Transesterification by Vaccinia Topoisomerase (2003) (9)
- Cyclin-Dependent Kinase 9 ( Cdk 9 ) of Fission Yeast Is Activated by the CDK-Activating Kinase Csk 1 , Overlaps Functionally with the TFIIH-Associated Kinase Mcs 6 , and Associates with the mRNA Cap Methyltransferase Pcm 1 In Vivo † (2006) (9)
- Characterization of the tRNA ligases of pathogenic fungi Aspergillus fumigatus and Coccidioides immitis (2016) (9)
- Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3′ processing and transcription termination that functions via its effects on CTD phosphatase Ssu72 (2020) (9)
- Structure and two-metal mechanism of fungal tRNA ligase (2018) (9)
- Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase (2016) (9)
- Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2 (2017) (8)
- Deletion of the rnl gene encoding a nick-sealing RNA ligase sensitizes Deinococcus radiodurans to ionizing radiation (2017) (8)
- Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast (2016) (8)
- Functional Groups Required for the Stability of Yeast RNA Triphosphatase in Vitro and in Vivo * (2001) (8)
- Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D (2011) (8)
- A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination (2020) (8)
- Structure of Fission Yeast Transcription Factor Pho7 Bound to pho1 Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis (2019) (8)
- Transcriptional networking cap-tures the 7SK RNA 5'-gamma-methyltransferase. (2007) (8)
- Substrate specificity and mutational analysis of Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease. (2011) (8)
- The DNA Repair Repertoire of Mycobacterium smegmatis FenA Includes the Incision of DNA 5′ Flaps and the Removal of 5′ Adenylylated Products of Aborted Nick Ligation (2017) (8)
- Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO–POL enzyme (2020) (8)
- Defining the Mer1 and Nam8 meiotic splicing regulons by cDNA rescue. (2011) (8)
- Biochemical Characterization of Mycobacterium smegmatis RnhC (MSMEG_4305), a Bifunctional Enzyme Composed of Autonomous N-Terminal Type I RNase H and C-Terminal Acid Phosphatase Domains (2015) (8)
- Deinococcus radiodurans RNA ligase exemplifies a novel ligase clade with a distinctive N-terminal module that is important for 5'-PO 4 nick sealing and ligase adenylylation but dispensable for phosphodiester formation at an adenylylated nick. (2007) (8)
- Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26 (2015) (8)
- Mechanistic insights into the manganese-dependent phosphodiesterase activity of yeast Dbr1 with bis-p-nitrophenylphosphate and branched RNA substrates (2016) (8)
- DNA strand transfer catalyzed by vaccinia topoisomerase: ligation of DNAs containing a 3' mononucleotide overhang. (2000) (8)
- Structure of 3′-PO4/5′-OH RNA ligase RtcB in complex with a 5′-OH oligonucleotide (2021) (7)
- Defining essential elements and genetic interactions of the yeast Lsm2–8 ring and demonstration that essentiality of Lsm2–8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24 (2018) (7)
- Effects of alanine cluster mutations in the D12 subunit of vaccinia virus mRNA (guanine-N7) methyltransferase. (2001) (7)
- Discrimination of RNA from DNA by polynucleotide phosphorylase. (2013) (7)
- Vaccinia topoisomerase mutants illuminate roles for Phe59, Gly73, Gln69 and Phe215. (2007) (7)
- Effects of DNA3′pp5′G capping on 3′ end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance (2015) (6)
- Deletions at the carboxyl terminus of vaccinia DNA topoisomerase affect DNA binding and enhance distributivity in DNA relaxation. (1997) (6)
- Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease activities (2018) (6)
- Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3’ processing and transcription termination (2019) (6)
- Activity and structure of Pseudomonas putida MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster (2019) (6)
- Structural insights to the metal specificity of an archaeal member of the LigD 3′-phosphoesterase DNA repair enzyme family (2011) (6)
- Box H/ACA snoRNAs are preferred substrates for the trimethylguanosine synthase in the divergent unicellular eukaryote Trichomonas vaginalis. (2012) (5)
- Analysis of topoisomerase-DNA interactions by electrophoretic mobility shift assay. (2001) (5)
- Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2′-PO4 recognition and ADP-ribosylation (2019) (5)
- NAD+ specificity of bacterial DNA ligase revealed. (2004) (5)
- The domain order of mammalian capping enzyme can be inverted and baculovirus phosphatase can function in cap formation in vivo. (2002) (5)
- Mutational analysis of baculovirus phosphatase identifies structural residues important for triphosphatase activity in vitro and in vivo. (2002) (5)
- Characterization of Runella slithyformis HD-Pnk, a Bifunctional DNA/RNA End-Healing Enzyme Composed of an N-Terminal 2′,3′-Phosphoesterase HD Domain and a C-Terminal 5′-OH Polynucleotide Kinase Domain (2016) (5)
- Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway (2011) (5)
- Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase (2021) (4)
- Inactivation of fission yeast Erh1 de-represses pho1 expression: evidence that Erh1 is a negative regulator of prt lncRNA termination (2020) (4)
- Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast (2022) (4)
- NAD+-dependent RNA terminal 2′ and 3′ phosphomonoesterase activity of a subset of Tpt1 enzymes (2019) (4)
- Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression (2022) (4)
- Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1 (2021) (4)
- Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease (2021) (4)
- Deinococcus radiodurans HD-Pnk, a Nucleic Acid End-Healing Enzyme, Abets Resistance to Killing by Ionizing Radiation and Mitomycin C (2018) (4)
- Transcriptional profiling of fission yeast RNA polymerase II CTD mutants (2021) (4)
- Distinctive structural basis for DNA recognition by the fission yeast Zn2Cys6 transcription factor Pho7 and its role in phosphate homeostasis. (2018) (4)
- Characterization of DNA Binding by the Isolated N-Terminal Domain of Vaccinia Virus DNA Topoisomerase IB. (2017) (4)
- The cytosolic DNA- and RNA-sensing pathways play important and non-redundant roles in host defense against vaccinia infection (2017) (3)
- Atomic structures of the RNA end-healing 5′-OH kinase and 2′,3′-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor (2019) (3)
- Chemical mutagenesis of vaccinia DNA topoisomerase lysine 167 provides insights to the catalysis of DNA transesterification. (2013) (3)
- Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules (2021) (3)
- DNA3′pp5′G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition (2015) (3)
- Intrinsic RNA ( Guanine-7 ) Methyltransferase Activity of the Vaccinia Virus Capping Enzyme D l Subunit-Is Stimulated by the Dl 2 Subunit (3)
- Purification and Characterization of a GTP-Pyrophosphate Exchange Activity from Vaccinia Virions ASSOCIATION OF THE GTP-PYROPHOSPHATE EXCHANGE ACTIVITY WITH VACCINIA mRNA GUANYLYLTRANSFERASE (GUANINE-7-)METHYLTRANSFERASE (CAPPING ENZYME) (2001) (3)
- Distinctive roles of translesion polymerases DinB1 and DnaE2 in diversification of the mycobacterial genome through substitution and frameshift mutagenesis (2022) (3)
- Mutational analysis of the 5′-OH oligonucleotide phosphate acceptor site of T4 polynucleotide kinase (2009) (3)
- Structures of Bacterial Polynucleotide Kinase in a Michaelis Complex with Nucleoside Triphosphate (NTP)-Mg2+ and 5′-OH RNA and a Mixed Substrate-Product Complex with NTP-Mg2+ and a 5′-Phosphorylated Oligonucleotide (2014) (3)
- Site-specific interaction of vaccinia virus topoisomerase I with duplex DNA. Minimal DNA substrate for strand cleavage in vitro. (1991) (3)
- Sequence-specific 1H, 13C and 15N assignments of the phosphoesterase (PE) domain of Pseudomonas aeruginosa DNA ligase D (LigD) (2011) (2)
- Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase ( Msm 0858 ) (2016) (2)
- Sequence-specific 1HN, 13C, and 15N backbone resonance assignments of the 34 kDa Paramecium bursaria Chlorella virus 1 (PBCV1) DNA ligase (2009) (2)
- Structures of RNA ligase RtcB in complexes with divalent cations and GTP. (2022) (2)
- Site-specific DNA Transesterification by Vaccinia Topoisomerase EFFECTS OF BENZO[a]PYRENE-dA, 8-OXOGUANINE, 8-OXOADENINE, AND 2-AMINOPURINE MODIFICATIONS*□S (2003) (2)
- Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection. (2019) (2)
- Structure-function analysis of fission yeast cleavage and polyadenylation factor (CPF) subunit Ppn1 and its interactions with Dis2 and Swd22 (2021) (2)
- Activity and substrate specificity of Candida, Aspergillus, and Coccidioides Tpt1: essential tRNA splicing enzymes and potential antifungal targets (2021) (2)
- Structure and Mechanism of T4 Polynucleotide Kinase (2002) (1)
- tRNA ligase (2019) (1)
- Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP (2018) (1)
- Abstract LB-306: Oncolytic vaccinia virus expressing immune checkpoint blockade antibody as cancer immunotherapeutics (2018) (1)
- Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. (2018) (1)
- Substrate analogs that trap the 2′-phospho-ADP-ribosylated RNA intermediate of the Tpt1 (tRNA 2′-phosphotransferase) reaction pathway (2020) (1)
- Kinetic mechanism of nick sealing by T 4 RNA ligase 2 and effects of 3 (2013) (1)
- cryo-EM structure of Mycobacterium smegmatis Lhr helicase C-terminal domain (2021) (0)
- Crystal Structure of RNA 17-mer UUCGGUUUUGAUCCGGA duplex (2013) (0)
- 455 Inhibition of the cytosolic DNA sensor cyclic GMP-AMP synthase by poxviral virulence factor E3 (2016) (0)
- Cryo-EM structure of AdnAB-AMPPNP-DNA complex (2019) (0)
- Jerard Hurwitz (1928–2019) (2019) (0)
- Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain (2010) (0)
- Structures of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily (2011) (0)
- Naegleria gruberi RNA ligase E227A mutant with ATP and Mn (2020) (0)
- Hnt3 in complex with DNA and guanosine (2015) (0)
- Functional Dynamics in Chlorella virus DNA Ligase (2009) (0)
- Abstract B031: Heat-inactivated modified vaccinia virus ankara induces type I IFN and antitumor immunity via the cytosolic DNA-sensing pathway (2016) (0)
- Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast (2022) (0)
- Crystal structure of a N-tagged Nuclease (2014) (0)
- NARBreakthroughArticle Division of labor among Mycobacteriumsmegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase (2017) (0)
- mycobacterial DNA ligase D complexed with ATP and MES (2019) (0)
- POL domain of Pol1 from M. smegmatis (2020) (0)
- Structure of Clostridium thermocellum polynucleotide kinase bound to dATP (2013) (0)
- Vaccinia virus capping enzyme complexed with SAH (monoclinic form) (2014) (0)
- Crystal Structure of Deinococcus radiodurans topoisomerase IB (2005) (0)
- Structure of Chlorella virus DNA ligase-adenylate bound to a 5' phosphorylated nick (2007) (0)
- Structure of bacterial polynucleotide kinase product complex bound to GDP and DNA (2013) (0)
- Naegleria gruberi RNA ligase K326A mutant with ATP and Mn (2020) (0)
- New Crystal Structure of Chlorella Virus DNA Ligase-Adenylate (2000) (0)
- Structure of bacterial polynucleotide kinase bound to GTP and pDNA (2014) (0)
- Mechanism ofmRNA capping by vaccinia virus guanylyltransferase : Characterization of an enzyme-guanylate intermediate ( covalent catalysis ) (2003) (0)
- NMR solution structures of Runella slithyformis RNA 2′-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity (2021) (0)
- 9 Capping Enzyme (1982) (0)
- Crystal structure of selenomethionine Msl5 protein in complex with RNA at 2.2 A (2014) (0)
- Pseudomonas putida MPE, a manganese-dependent endonuclease of the binuclear metallophosphoesterase superfamily, incises single-strand DNA in two orientations to yield a mixture of 3′-PO4 and 3′-OH termini (2020) (0)
- Structure of T4Pnkp 3' phosphatase covalently bound to BeF3 (2017) (0)
- X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH SULFATE AND MANGANESE IONS. (1999) (0)
- Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain (2006) (0)
- Naegleria gruberi RNA ligase K170A mutant apo (2020) (0)
- Structure/function Correlations in P. aeruginosa DNA Ligase LigD (2009) (0)
- Mycobacterium smegmatis DNA flap endonuclease (2018) (0)
- Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase. (2016) (0)
- Vaccinia virus E5 is a dominant inhibitor of the cytosolic DNA sensor cGAS (2019) (0)
- 020 The combination of intratumoral delivery of inactivated modified vaccinia virus Ankara with systemic delivery of immune checkpoint blockade enhances antitumor immunity (2018) (0)
- Monoclinic Mimivirus Capping Enzyme Triphosphatase. (2008) (0)
- Luprostiol in Dairy Cows: Residue Depletion and Metabolism (1992) (0)
- Structure–activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB (2021) (0)
- Crystal structure of a C-tagged Nuclease (2014) (0)
- Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+ATP (2015) (0)
- Crystal structure of phosphoesterase (2014) (0)
- Crystal Structure of C. Thermocellum PNKP Ligase Domain Apo Form (2012) (0)
- Structure and mechanism of a eukaryal nick-sealing RNA ligase (2015) (0)
- POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP (2020) (0)
- Encephalitozooan cuniculi mRNA Cap (Guanine-N7) Methyltransferasein complexed with AzoAdoMet (2005) (0)
- Naegleria gruberi RNA ligase R4a K121A mutant apo (2020) (0)
- Factor-dependent Transcription Termination by Vaccinia Virus (2001) (0)
- Identification of Novel Antipoxviral Agents: Mitoxantrone Inhibits Vaccinia Virus Replication by Blocking Virion Assembly (cid:1) (2007) (0)
- Crystal structure of RtcA.AMP product complex (2011) (0)
- Vaccinia virus capping enzyme complexed with SAH in P1 form (2014) (0)
- Genetic screen for suppression of transcriptional interference reveals fission yeast 14–3–3 protein Rad24 as an antagonist of precocious Pol2 transcription termination (2021) (0)
- 904 The cytosolic dsRNA-sensing pathway mediated by MDA5/MAVS/IRF3 is critical for the induction of type I and III IFNs after viral infection of skin keratinocytes (2018) (0)
- Structure of bacterial polynucleotide kinase Michaelis complex bound to GTP and DNA (2013) (0)
- Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination. (2023) (0)
- TYPE 1-TOPOISOMERASE CATALYTIC FRAGMENT FROM VACCINIA VIRUS (1999) (0)
- LB980 Transcriptomic profiling reveals mechanisms of host restriction of modified vaccinia virus Ankara replication in murine primary fibroblasts (2017) (0)
- Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese (2006) (0)
- 5 ' 6 helicase that unwinds 3 '-tailed RNA duplexes and RNA : DNA hybrids 7 8 (2015) (0)
- CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME (2001) (0)
- Investigation of the immunological mechanisms underlying the attenuation of vaccinia virus lacking host-range factor C7 (2018) (0)
- Naegleria gruberi RNA ligase K170A mutant with ATP and Mn (2020) (0)
- Crystal Structure of the Phosphatase Domain of C. thermocellum (Bacterial) PnkP (2013) (0)
- Escherichia coli LigA (K115M) in complex with NAD (2017) (0)
- 834 Rational design of recombinant modified vaccinia virus Ankara for cancer immunotherapy (2019) (0)
- Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis (2022) (0)
- Sue Golding Graduate Student Symposia - Abstracts of December 16, 1980 (2016) (0)
- Covalent Catalysis in Nucleotidyl Transfer (2001) (0)
- X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION. (1999) (0)
- 034 Recombinant replication competent attenuated vaccinia virus expressing human Flt3L for cancer immunotherapy (2016) (0)
- Mycobacterium smegmatis flap endonuclease mutant D208N (2018) (0)
- Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States (2022) (0)
- T4 polynucleotide kinase/phosphatase with bound sulfate and magnesium. (2007) (0)
- T4 RNA Ligase 1 (K99M) (2017) (0)
- Mycobacterial helicase Lhr abets resistance to DNA crosslinking agents mitomycin C and cisplatin (2023) (0)
- Crystal structure of the yeast DEAD-box splicing factor Prp28 at 2.54 Angstroms resolution (2014) (0)
- Crystal structure of RtcA.ATP binary complex (2011) (0)
- Naegleria gruberi RNA ligase E312A mutant with AMP and Mn (2020) (0)
- Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase–pyrophosphatases that act via a covalent aspartyl–phosphate intermediate (2022) (0)
- strands to rna covalent binding of dna catalyzed by vaccinia topoisomerase (1998) (0)
- Structure of Chlorella virus DNA ligase-product DNA complex (2007) (0)
- Crystal Structure of C. Thermocellum PNKP Ligase Domain AMP-Adenylate (2012) (0)
- Triclinic structure of Mimivirus Capping Enzyme Triphosphatase at 1.65 A (2008) (0)
- Crystal Structure of Fungal RNA Kinase (2019) (0)
- Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation (2020) (0)
- Vaccinia virus capping enzyme complexed with GTP and SAH (2014) (0)
- Structure-Function Analysis of the Phosphoesterase Component of the Nucleic Acid End-Healing Enzyme Runella slithyformis HD-Pnk (2019) (0)
- Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP (2017) (0)
- Vaccinia virus host-range factor C7 has dual inhibitory functions in type I IFN production and signaling (2017) (0)
- Crystal Structure of Pho7 complex with pho1 promoter site 2 (2019) (0)
- LB981 Comparative transcriptomic profiling of murine conventional dendritic cells infected with live or heat-inactivated modified vaccinia virus Ankara (2017) (0)
- CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME (2001) (0)
- Naegleria gruberi RNA ligase with PPi (2020) (0)
- Abstract A007: Intratumoral delivery of inactivated vaccinia virus is more efficacious than live oncolytic vaccinia virus in murine bilateral tumor implantation models (2016) (0)
- Crystal Structure of the P. aeruginosa LigD phosphoesterase domain (2010) (0)
- Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis (2023) (0)
- Crystal Structure of C. thermocellum PNKP Ligase domain in complex with ATP (2012) (0)
- Pyrococcus RNA ligase (2021) (0)
- Cobalt bound structure of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme family (2011) (0)
- Crystal structure of RtcA.ATP.Co ternary complex (2011) (0)
- Crystal Structure of the Ligase Domain from M. tuberculosis LigD at 2.4A (2006) (0)
- Crystal structure of Pseudomonas putida nuclease MPE (2019) (0)
- Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA (2019) (0)
- DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, CARDIOVASCULAR, AND CANCER CENTER 2015-2016 SEMINAR SCHEDULE* (2016) (0)
- Crystal structure of E. coli RNA 3' cyclase (2010) (0)
- Full-length M. smegmatis Pol1 (2020) (0)
- Crystal structure of Msl5 protein in complex with RNA at 1.8 A (2014) (0)
- Abstract PR09: Intratumoral delivery of engineered modified vaccinia virus Ankara expressing Flt3L and OX40L for "in situ" therapeutic cancer vaccination (2019) (0)
- Mycobacterium smegmatis DNA flap endonuclease mutant D125N (2018) (0)
- Identification of novel antipoxviral agents : Mitoxantrone inhibits vaccinia virus 10 replication by blocking virion assembly 11 12 13 14 (2007) (0)
- Structure of mycobacterial 3 (cid:2) -to-5 (cid:2) RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases (2017) (0)
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What Schools Are Affiliated With Stewart Shuman?
Stewart Shuman is affiliated with the following schools:
