Subburaman Mohan
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Subburaman Mohan's Degrees
- PhD Computer Science Stanford University
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(Suggest an Edit or Addition)Subburaman Mohan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. (1997) (1116)
- IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. (2002) (455)
- Growth factors for bone growth and repair: IGF, TGFβ and BMP (1996) (416)
- Growth factors to stimulate bone formation (1993) (398)
- The role of liver-derived insulin-like growth factor-I. (2009) (397)
- Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. (2000) (391)
- Bone growth factors. (1991) (379)
- Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action. (1989) (357)
- Studies on the Mechanisms by Which Insulin-like Growth Factor (IGF) Binding Protein-4 (IGFBP-4) and IGFBP-5 Modulate IGF Actions in Bone Cells (*) (1995) (309)
- Homozygous and heterozygous expression of a novel insulin-like growth factor-I mutation. (2005) (303)
- Acute effect of brief low- and high-intensity exercise on circulating insulin-like growth factor (IGF) I, II, and IGF-binding protein-3 and its proteolysis in young healthy men. (1996) (285)
- Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness. (1999) (247)
- The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model. (1999) (237)
- Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging. (1994) (222)
- Quantitation of growth factors IGF‐I, SGF/IGF‐II, and TGF‐β in human dentin (1990) (218)
- Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation. (1990) (213)
- Evidence that IGF-binding protein-5 functions as a growth factor. (2001) (211)
- Estrogen receptor specificity in the regulation of the skeleton in female mice. (2001) (199)
- The insulin-like growth factor system and the coupling of formation to resorption. (1995) (198)
- Effect of brief exercise on circulating insulin-like growth factor I. (1994) (195)
- Comparison of the biological actions of TGF beta‐1 and TGF beta‐2: Differential activity in endothelial cells (1988) (194)
- Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis. (1993) (193)
- Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-II. (1988) (193)
- Serum levels of insulin-like growth factor system components and relationship to bone metabolism in Type 1 and Type 2 diabetes mellitus patients. (1998) (192)
- Parathyroid hormone stimulates release of insulin-like growth factor-I (IGF-I) and IGF-II from neonatal mouse calvaria in organ culture. (1989) (191)
- Physical fitness, endurance training, and the growth hormone-insulin-like growth factor I system in adolescent females. (1996) (189)
- Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. (2003) (185)
- Bayesian Shrinkage Estimation of Quantitative Trait Loci Parameters (2005) (177)
- Growth factors for bone growth and repair: IGF, TGF beta and BMP. (1996) (175)
- Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells (1990) (174)
- Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells. (1990) (172)
- Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities. (1997) (171)
- Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone. (1991) (168)
- Tumor Necrosis Factor-like Weak Inducer of Apoptosis Inhibits Skeletal Myogenesis through Sustained Activation of Nuclear Factor-κB and Degradation of MyoD Protein* (2006) (165)
- Evidence that anabolic effects of PTH on bone require IGF-I in growing mice. (2001) (157)
- The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments (2015) (142)
- The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification (2018) (140)
- Estradiol stimulates in vitro the secretion of insulin-like growth factors by the clonal osteoblastic cell line, UMR106. (1989) (139)
- Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair. (2006) (136)
- Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases. (1994) (135)
- Low‐amplitude, low‐frequency electric field‐stimulated bone cell proliferation may in part be mediated by increased IGF‐II release (1992) (134)
- Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain. (1999) (134)
- 1,25-Dihydroxyvitamin D3 differentially regulates the production of insulin-like growth factor I (IGF-I) and IGF-binding protein-4 in mouse osteoblasts. (1991) (129)
- Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates. (1990) (128)
- Insulin-like Growth Factor-binding Protein 5 (IGFBP-5) Interacts with a Four and a Half LIM Protein 2 (FHL2)* (2002) (127)
- Differential effects on bone of estrogen receptor α and androgen receptor activation in orchidectomized adult male mice (2003) (126)
- Development of a simple valid method for the complete removal of insulin-like growth factor (IGF)-binding proteins from IGFs in human serum and other biological fluids: comparison with acid-ethanol treatment and C18 Sep-Pak separation. (1995) (125)
- Attenuation of Posttraumatic Muscle Catabolism and Osteopenia by Long-Term Growth Hormone Therapy (2001) (123)
- Insulin‐Like Growth Factor (IGF) System Components in Human Prostatic Cancer Cell‐Lines: LNCaP, DU145, and PC‐3 Cells (1996) (122)
- Overexpression of Insulin-Like Growth Factor-Binding Protein-2 in Transgenic Mice Reduces Postnatal Body Weight Gain. (1999) (120)
- Modulation of insulin‐like growth factor actions in L6A1 myoblasts by insulin‐like growth factor binding protein (IGFBP)‐4 and IGFBP‐5: A dual role for IGFBP‐5 (1998) (119)
- Increased physical activity and the growth hormone-IGF-I axis in adolescent males. (1998) (119)
- Insulin-like growth factor binding proteins in bone cell regulation. (1993) (119)
- Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice. (2000) (118)
- Combined magnetic fields increase insulin-like growth factor-II in TE-85 human osteosarcoma bone cell cultures. (1995) (115)
- Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion. (2007) (114)
- Down‐Regulation of the Serum Stimulatory Components of the Insulin‐like Growth Factor (IGF) System (IGF‐I, IGF‐II, IGF Binding Protein [BP]‐3, and IGFBP‐5) in Age‐Related (Type II) Femoral Neck Osteoporosis (1999) (113)
- Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease. (2000) (112)
- Fitness, training, and the growth hormone-->insulin-like growth factor I axis in prepubertal girls. (2001) (111)
- Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids. (1995) (107)
- Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women. (1998) (107)
- Postnatal and Pubertal Skeletal Changes Contribute Predominantly to the Differences in Peak Bone Density Between C3H/HeJ and C57BL/6J Mice (2001) (106)
- Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily. (1998) (106)
- Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice (2005) (105)
- Pregnancy-associated plasma protein-A accounts for the insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) proteolytic activity in human pregnancy serum and enhances the mitogenic activity of IGF by degrading IGFBP-4 in vitro. (2001) (102)
- Interactions of growth factors present in bone matrix with bone cells: effects on DNA synthesis and alkaline phosphatase. (1990) (102)
- Structure-Function Analysis of the Human Insulin-like Growth Factor Binding Protein-4* (1998) (102)
- Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction. (1991) (102)
- Human Osteoblasts' Proliferative Responses to Strain and 17β‐Estradiol Are Mediated by the Estrogen Receptor and the Receptor for Insulin‐Like Growth Factor I (2002) (101)
- The multi-functional role of insulin-like growth factor binding proteins in bone (2005) (101)
- Effects of Liver‐Derived Insulin‐Like Growth Factor I on Bone Metabolism in Mice (2002) (100)
- Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1 (2009) (99)
- Quantitation of growth factors IGF-I, SGF/IGF-II, and TGF-beta in human dentin. (1990) (98)
- Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism. (2001) (95)
- Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice. (2000) (93)
- Age-related changes in IGFBP-4 and IGFBP-5 levels in human serum and bone: implications for bone loss with aging. (1995) (91)
- Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice. (2007) (91)
- Insulin-like growth factor (IGF)-binding proteins in serum--do they have additional roles besides modulating the endocrine IGF actions? (1996) (90)
- Recombinant synthesis of insulin-like growth factor-binding protein-4 (IGFBP-4): Development, validation, and application of a radioimmunoassay for IGFBP-4 in human serum and other biological fluids. (1996) (90)
- Progesterone and promegestone stimulate human bone cell proliferation and insulin-like growth factor-2 production. (1992) (90)
- Insulin-like growth factor system components and the coupling of bone formation to resorption. (1996) (90)
- Studies on the potential mediators of skeletal changes occurring during puberty in girls. (1999) (88)
- Nuclear Factor-E2-related Factor-1 Mediates Ascorbic Acid Induction of Osterix Expression via Interaction with Antioxidant-Responsive Element in Bone Cells* (2007) (87)
- Multiple osteocalcin fragments in human urine and serum as detected by a midmolecule osteocalcin radioimmunoassay. (1990) (87)
- Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo. (2006) (86)
- Genetic control of the rate of wound healing in mice (2001) (84)
- Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population. (2001) (83)
- Development of valid methods to measure insulin-like growth factors-I and -II in bone cell-conditioned medium. (1990) (83)
- Up date on IGFBP-4: regulation of IGFBP-4 levels and functions, in vitro and in vivo. (2004) (83)
- Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro. (1993) (83)
- Insulin‐like Growth Factor (IGF)‐I, ‐II, IGF Binding Proteins (IGFBP)−3, −4, and −5 Levels in the Conditioned Media of Normal Human Bone Cells Are Skeletal Site‐Dependent (1997) (79)
- The 24/25-kDa serum insulin-like growth factor-binding protein is increased in elderly women with hip and spine fractures. (1992) (79)
- Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice. (2005) (79)
- Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity (2008) (76)
- The role of estrogen receptor α in growth plate cartilage for longitudinal bone growth (2010) (76)
- Two Different Pathways for the Maintenance of Trabecular Bone in Adult Male Mice (2002) (76)
- A Missense Mutation in the Mouse Col2a1 Gene Causes Spondyloepiphyseal Dysplasia Congenita, Hearing Loss, and Retinoschisis (2003) (73)
- Analysis of gene expression in the wound repair/regeneration process (2001) (72)
- Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. (2002) (72)
- ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. (2002) (72)
- Evidence that the interaction between insulin-like growth factor (IGF)-II and IGF binding protein (IGFBP)-4 is essential for the action of the IGF-II-dependent IGFBP-4 protease. (2000) (71)
- Genetic evidence that thyroid hormone is indispensable for prepubertal insulin‐like growth factor–I expression and bone acquisition in mice (2012) (70)
- Evidence for a role for insulin-like growth factor binding proteins in glucocorticoid inhibition of normal human osteoblast-like cell proliferation. (1996) (70)
- Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development (2013) (69)
- Serum Levels of Insulin-Like Growth Factor (IGF); IGF-Binding Proteins-3, -4, and -5; and Their Relationships to Bone Mineral Density and the Risk of Vertebral Fractures in Postmenopausal Women (2006) (69)
- Quantitative Trait Loci for Bone Density in Mice: The Genes Determining Total Skeletal Density and Femur Density Show Little Overlap in F2 Mice (2002) (69)
- Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains. (2005) (68)
- Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells. (1995) (68)
- Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo. (1999) (68)
- Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice (2007) (68)
- Associations of insulin‐like growth factors, insulin‐like growth factor binding proteins and acid‐labile subunit with coronary heart disease (2004) (67)
- The anabolic effects of GH/IGF system on bone. (2004) (67)
- Impaired skeletal growth in mice with haploinsufficiency of IGF-I: genetic evidence that differences in IGF-I expression could contribute to peak bone mineral density differences. (2005) (67)
- Insulin-like growth factor system components in hyperparathyroidism and renal osteodystrophy. (2000) (67)
- Fluid Shear Stress Synergizes with Insulin-like Growth Factor-I (IGF-I) on Osteoblast Proliferation through Integrin-dependent Activation of IGF-I Mitogenic Signaling Pathway* (2005) (65)
- Development of a new radioimmunoassay for human osteocalcin: evidence for a midmolecule epitope. (1988) (65)
- Effect of therapy with recombinant human growth hormone on insulin-like growth factor system components and serum levels of biochemical markers of bone formation in children after severe burn injury (1998) (65)
- Retinoic acid regulates insulin-like growth factor-binding protein expression in human osteoblast cells. (1996) (64)
- Mechanical Strain Stimulates ROS Cell Proliferation Through IGF‐II and Estrogen Through IGF‐I (1999) (63)
- Recombinant Human Insulin-Like Growth Factor-Binding Protein-5 Stimulates Bone Formation Parameters in Vitro and in Vivo1. (1999) (63)
- Studies on regulation of insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 production in human bone cells. (1992) (63)
- 1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo. (1993) (61)
- Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. (2007) (60)
- Characterization of mitogenic activities extracted from bovine bone matrix. (1986) (60)
- Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice. (2010) (60)
- Effects of Secreted Frizzled‐Related Protein 3 on Osteoblasts In Vitro (2004) (59)
- Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women. (2004) (59)
- Regulation of insulin‐like growth factors I and II and their binding proteins in human bone marrow stromal cells by dexamethasone (1998) (59)
- DNA Microarrays: Their Use and Misuse (2002) (59)
- Serum levels of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-1 to -6 and their relationship to bone metabolism in osteoporosis patients. (2003) (58)
- Epiphyseal Chondrocyte Secondary Ossification Centers Require Thyroid Hormone Activation of Indian Hedgehog and Osterix Signaling (2014) (58)
- Increased physical activity and the growth hormone-IGF-I axis in adolescent males. (1998) (57)
- A time course of bone response to jump exercise in C57BL/6J mice (2002) (57)
- Spontaneous Fractures in the Mouse Mutant sfx Are Caused by Deletion of the Gulonolactone Oxidase Gene, Causing Vitamin C Deficiency (2005) (57)
- Role of WNT16 in the regulation of periosteal bone formation in female mice. (2015) (56)
- An inhibitory insulin-like growth factor binding protein (In-IGFBP) from human prostatic cell conditioned medium reveals N-terminal sequence identity with bone derived In-IGFBP. (1990) (56)
- Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency. (2005) (56)
- Growth hormone (GH) treatment of GH-deficient children increases serum levels of insulin-like growth factors (IGFs), IGF-binding protein-3 and -5, and bone alkaline phosphatase isoenzyme. (1996) (56)
- Autocrine regulators of MC3T3‐E1 cell proliferation (1993) (54)
- Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross. (2006) (54)
- Gene Expression Patterns in the Hypoxic Murine Placenta: A Role in Epigenesis? (2007) (53)
- Ras‐Association Domain Family 1 Protein, RASSF1C, Is an IGFBP‐5 Binding Partner and a Potential Regulator of Osteoblast Cell Proliferation (2005) (52)
- Serum Levels of Insulin‐like Growth Factor Binding Proteins (IGFBP)–4 and –5 Correlate with Bone Mineral Density in Growth Hormone (GH)–Deficient Adults and Increase with GH Replacement Therapy (1998) (52)
- Expression and insulin-like growth factor-dependent proteolysis of insulin-like growth factor-binding protein-4 are regulated by cell confluence in vascular smooth muscle cells. (1994) (52)
- Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading. (2011) (51)
- Intact IGF-binding protein-4 and -5 and their respective fragments isolated from chronic renal failure serum differentially modulate IGF-I actions in cultured growth plate chondrocytes. (2001) (51)
- Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice. (1999) (50)
- Serum insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 in children with chronic renal failure: relationship to growth and glomerular filtration rate (2000) (50)
- Serum insulin-like growth factor-I, insulin-like growth factor binding proteins, and bone mineral content in hyperthyroidism. (2000) (50)
- Pregnancy-associated Plasma Protein-A Regulates Myoblast Proliferation and Differentiation through an Insulin-like Growth Factor-dependent Mechanism* (2005) (49)
- Human prostatic cancer cells, PC3, elaborate mitogenic activity which selectively stimulates human bone cells. (1990) (49)
- Studies on the Role of Human Insulin‐like Growth Factor‐II (IGF‐II)‐Dependent IGF Binding Protein (hIGFBP)‐4 Protease in Human Osteoblasts Using Protease‐Resistant IGFBP‐4 Analogs (1999) (48)
- Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress. (2009) (47)
- Calcitonin Increases the Concentration of Insulin-Like Growth Factors in Serum-Free Cultures of Human Osteoblast-Line Cells (2000) (46)
- Insulin-like growth factor-binding protein-5 inhibits growth and induces differentiation of mouse osteosarcoma cells. (2001) (46)
- Role of Insulin-like Growth Factor-1 in the Regulation of Skeletal Growth (2012) (46)
- Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children: a report of the Southwest Pediatric Nephrology Study Group. (1999) (45)
- Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation. (2006) (45)
- Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H/HeJ mice. (2001) (45)
- Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway. (2011) (44)
- Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis (2010) (44)
- Peak oxygen uptake, muscle volume, and the growth hormone-insulin-like growth factor-I axis in adolescent males. (1998) (44)
- Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice. (2003) (44)
- Elevated Aromatase Expression in Osteoblasts Leads to Increased Bone Mass Without Systemic Adverse Effects (2009) (44)
- Isolation and purification of a low-molecular-weight skeletal growth factor from human bones. (1986) (43)
- Heterogeneity of latent transforming growth factor-beta isolated from bone matrix proteins. (1990) (43)
- Treatment with the Oral Growth Hormone Secretagogue MK‐677 Increases Markers of Bone Formation and Bone Resorption in Obese Young Males (1998) (43)
- T‐box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2 (2009) (43)
- Circulating levels of insulin-like growth factor-I and -II, and IGF-binding protein-3 in inflammation and after parathyroid hormone infusion. (1994) (42)
- Genetic variation in bone-regenerative capacity among inbred strains of mice. (2001) (42)
- Targeted disruption of leucine‐rich repeat kinase 1 but not leucine‐rich repeat kinase 2 in mice causes severe osteopetrosis (2013) (41)
- Insulin‐like growth factor binding protein–4 inhibits both basal and IGF‐mediated chick pelvic cartilage growth in vitro (1993) (41)
- Human skeletal growth factor stimulates collagen synthesis and inhibits proliferation in a clonal osteoblast cell line (MC3T3‐E1) (1986) (41)
- Studies on human pregnancy-induced insulin-like growth factor (IGF)-binding protein-4 proteases in serum: determination of IGF-II dependency and localization of cleavage site. (2000) (40)
- Ras association domain family 1C protein stimulates human lung cancer cell proliferation. (2006) (40)
- An age-related decrease in the concentration of insulin-like growth factor binding protein-5 in human cortical bone (1995) (40)
- Evidence that human bone cells in culture secrete insulin‐like growth factor (IGF)‐II and IGF binding protein‐3 but not acid‐labile subunit both under basal and regulated conditions (1995) (40)
- Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice. (2003) (39)
- Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration. (2000) (39)
- Targeted Disruption of Ephrin B1 in Cells of Myeloid Lineage Increases Osteoclast Differentiation and Bone Resorption in Mice (2012) (39)
- Effect of tumor necrosis factor-alpha on the expression of insulin-like growth factor I and insulin-like growth factor binding protein 4 in mouse osteoblasts. (1994) (39)
- Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice. (2003) (39)
- A mouse tumor-derived osteolytic factor stimulates bone resorption by a mechanism involving local prostaglandins production in bone. (1985) (38)
- Effects of extracellular calcium on insulin‐like growth factor II in human bone cells (1995) (38)
- PTH stimulates the proliferation of TE-85 human osteosarcoma cells by a mechanism not involving either increased cAMP or increased secretion of IGF-I, IGF-II or TGF beta. (1992) (38)
- Quantitative Assessment of Forearm Muscle Size, Forelimb Grip Strength, Forearm Bone Mineral Density, and Forearm Bone Size in Determining Humerus Breaking Strength in 10 Inbred Strains of Mice (2001) (38)
- Fracture Healing in Mice Deficient in Plasminogen Activator Inhibitor-1 (2008) (38)
- Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice. (2002) (37)
- Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation (2012) (37)
- Skeletal growth factor is produced by human osteoblast-like cells in culture. (1986) (37)
- Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity (2016) (36)
- Skeletal effects of growth hormone and insulin-like growth factor-I therapy (2016) (36)
- Contribution of marrow stromal cells to the regulation of osteoblast proliferation in rats: evidence for the involvement of insulin-like growth factors. (1991) (35)
- A urine midmolecule osteocalcin assay shows higher discriminatory power than a serum midmolecule osteocalcin assay during short-term alendronate treatment of osteoporotic patients. (2002) (35)
- Inhibition of mechanosensitive cation channels inhibits myogenic differentiation by suppressing the expression of myogenic regulatory factors and caspase‐3 activity (2005) (35)
- Intact insulin‐like growth factor binding protein‐5 (IGFBP‐5) associates with bone matrix and the soluble fragments of IGFBP‐5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2‐treatment (1996) (35)
- Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture (1993) (35)
- Leptin Receptor (Lepr) Is a Negative Modulator of Bone Mechanosensitivity and Genetic Variations in Lepr May Contribute to the Differential Osteogenic Response to Mechanical Stimulation in the C57BL/6J and C3H/HeJ Pair of Mouse Strains* (2010) (34)
- IGF System Components and Their Role in Bone Metabolism (1999) (34)
- Long-term Consequences of Traumatic Brain Injury in Bone Metabolism (2018) (34)
- Insulin-like growth factor-binding protein-6 produced by human PC-3 prostate cancer cells: isolation, characterization and its biological action. (1996) (34)
- IGFBP-4 regulates adult skeletal growth in a sex-specific manner (2017) (34)
- Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6. (2001) (33)
- Mapping the dominant wound healing and soft tissue regeneration QTL in MRL × CAST (2005) (32)
- The Role of GH/IGF-I-Mediated Mechanisms in Sex Differences in Cortical Bone Size in Mice (2010) (32)
- Bioactivity of a 29-Kilodalton Insulin-Like Growth Factor Binding Protein-3 Fragment Present in Excess in Chronic Renal Failure Serum (1997) (32)
- Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice. (2008) (31)
- Ethinylestradiol and testosterone have divergent effects on circulating IGF system components in adolescents with constitutional tall stature. (2005) (31)
- EphA4 Receptor Is a Novel Negative Regulator of Osteoclast Activity (2014) (31)
- Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies. (2016) (31)
- Reduced Bone Mineral Density in SOCS-2-Deficient Mice (2005) (31)
- Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise. (2015) (30)
- Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J (2002) (30)
- Evaluation of signal transduction mechanisms for the mitogenic effects of prostaglandin E2 in normal human bone cells in vitro (1996) (30)
- Conditional Disruption of the Prolyl Hydroxylase Domain‐Containing Protein 2 (Phd2) Gene Defines Its Key Role in Skeletal Development (2014) (30)
- Effects of Recombinant Insulin-Like Growth Factor-Binding Protein-4 on Bone Formation Parameters in Mice1. (1999) (29)
- Studies on the regulation of insulin‐like growth factor binding protein 3 secretion in human osteosarcoma cells in vitro (1994) (29)
- Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice. (2007) (29)
- Targeted Disruption of TGFBI in Mice Reveals Its Role in Regulating Bone Mass and Bone Size through Periosteal Bone Formation (2012) (29)
- Osteogenic Protein-1 Stimulates mRNA Levels of BMP-6 and Decreases mRNA Levels of BMP-2 and -4 in Human Osteosarcoma Cells (1997) (29)
- Transforming growth factor beta mediates the estrogen induced inhibition of UMR106 cell growth. (1989) (29)
- Characterization of the receptor for insulin‐like growth factor II in bone cells (1989) (29)
- A critical evaluation of the effect of population size and phenotypic measurement on QTL detection and localization using a large F2 murine mapping population (2006) (28)
- Differential regulation of pregnancy associated plasma protein (PAPP)-A during pregnancy in human and mouse. (2002) (28)
- The diagnosis and treatment of osteoporosis: future prospects. (1999) (28)
- Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis. (2002) (28)
- Insulin-like growth factor II and transforming growth factor beta 1 regulate insulin-like growth factor I secretion in mouse bone cells. (1991) (28)
- Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system. (2002) (28)
- Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice. (2007) (28)
- Effects of therapy with recombinant human growth hormone on insulin-like growth factor system components and serum levels of biochemical markers of bone formation in children after severe burn injury. (1998) (28)
- Regulation of insulin-like growth factor binding protein-5, four and a half lim-2, and a disintegrin and metalloprotease-9 expression in osteoblasts. (2006) (27)
- Growth hormone stimulates cortical bone formation in immature hypophysectomized rats. (1992) (27)
- Effects of Reduced Dialysate Calcium on Calcium-Phosphorus Product and Bone Metabolism in Hemodialysis Patients (2004) (27)
- IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots (2017) (27)
- Potential involvement of the interaction between insulin‐like growth factor binding protein (IGFBP)‐6 and LIM mineralization protein (LMP)‐1 in regulating osteoblast differentiation (2008) (27)
- Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation (2017) (27)
- Decreased locomotor activity in mice expressing tTA under control of the CaMKIIα promoter (2008) (27)
- Development and Application of a Serum C-Telopeptide and Osteocalcin Assay to Measure Bone Turnover in an Ovariectomized Rat Model (2000) (27)
- Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice. (2005) (27)
- Recommendations for nomenclature of the insulin-like growth factor binding protein (IGFBP) superfamily. (1998) (26)
- Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily. (1998) (26)
- Fibroblast growth factor enhances human chorionic gonadotropin synthesis independent of mitogenic stimulation in Jar choriocarcinoma cells. (1988) (26)
- Serum insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases (1997) (26)
- Targeted Overexpression of Osteoactivin in Cells of Osteoclastic Lineage Promotes Osteoclastic Resorption and Bone Loss in Mice (2012) (26)
- Chromosomal regions harboring genes for the work to femur failure in mice (2002) (26)
- Inactivation of insulin-like-growth factors diminished the anabolic effects of pregnancy-associated plasma protein-A (PAPP-A) on bone in mice. (2010) (25)
- Multiple Genetic Loci From CAST/EiJ Chromosome 1 Affect vBMD Either Positively or Negatively in a C57BL/6J Background (2005) (25)
- Transgenic Overexpression of Ephrin B1 in Bone Cells Promotes Bone Formation and an Anabolic Response to Mechanical Loading in Mice (2013) (25)
- High Osteoblastic Activity In C3H/HeJ Mice Compared to C57BL/6J Mice Is Associated with Low Apoptosis in C3H/HeJ Osteoblasts (2006) (25)
- Direct measurement of IGF-I and IGFBP-3 in bronchoalveolar lavage fluid from idiopathic pulmonary fibrosis (2001) (25)
- RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1 (2012) (24)
- A New Monoclonal Antibody ELISA for Detection and Characterization of C-telopeptide Fragments of Type I Collagen in Urine (2001) (24)
- Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation. (2016) (24)
- CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance (2018) (24)
- Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system. (1991) (24)
- Characterization of the IGF regulatory system in bone. (1993) (23)
- Dibutyryl cyclic adenosine monophosphate differentially regulates cell proliferation in low and high alkaline phosphatase SaOS‐2 human osteosarcoma cells: Evidence for mediation by the insulin‐like growth factor‐II system (1993) (22)
- Metabolic control and bone health in adolescents with type 1 diabetes (2011) (22)
- Renal Osteodystrophy: New Insights in Pathophysiology and Treatment Modalities with Special Emphasis on the Insulin-Like Growth Factor System (1998) (21)
- Development and evaluation of C-telopeptide enzyme-linked immunoassay for measurement of bone resorption in mouse serum. (2000) (21)
- Insulin‐Like Growth Factor I Effect on the Number of Osteoblast Progenitors Is Impaired in Ovariectomized Mice (2002) (21)
- The negative impact of traumatic brain injury (TBI) on bone in a mouse model (2014) (21)
- Chemical and biological characterization of low-molecular-weight human skeletal growth factor. (1986) (21)
- Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice. (2013) (20)
- New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129×1/SvJ inbred strains of mice (2006) (20)
- Role of IGF1 and EFN-EPH signaling in skeletal metabolism. (2018) (20)
- Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen. (1989) (19)
- Insulin-like growth factor-I and insulin-like growth factor-II induce c-fos in mouse osteoblastic cells (1990) (19)
- HSV-1 amplicon-mediated transfer of 128-kb BMP-2 genomic locus stimulates osteoblast differentiation in vitro. (2004) (19)
- Disruption of Four-and-a-Half LIM 2 Decreases Bone Mineral Content and Bone Mineral Density in Femur and Tibia Bones of Female Mice (2006) (19)
- Sca-1+ Hematopoietic Cell-based Gene Therapy with a Modified FGF-2 Increased Endosteal/Trabecular Bone Formation in Mice. (2007) (18)
- Serum levels of insulin‐like growth factor binding proteins in Ecuadorean children with growth hormone insensitivity (1999) (18)
- Conditional disruption of the osterix gene in chondrocytes during early postnatal growth impairs secondary ossification in the mouse tibial epiphysis (2019) (18)
- Hammerhead ribozyme-mediated cleavage of the human insulin-like growth factor-II ribonucleic acid in vitro and in prostate cancer cells. (1999) (18)
- Mechanism of mitogenic action of aluminum ion on human bone cells: potential involvement of the insulin-like growth factor regulatory system. (1993) (18)
- Liver-derived IGF-I regulates kidney size, sodium reabsorption, and renal IGF-II expression. (2007) (18)
- Mapping quantitative trait loci that influence blood levels of alkaline phosphatase in MRL/MpJ and SJL/J mice. (2004) (18)
- Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross. (2007) (18)
- Beta 2-microglobulin is not a bone cell mitogen. (1989) (18)
- The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo. (2007) (18)
- Urokinase plasminogen activator gene deficiency inhibits fracture cartilage remodeling (2014) (17)
- Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. (2002) (17)
- Concentrations of insulin-like growth factor (IGF)-I, -II, and IGF binding protein-4, and -5 in human bone cell conditioned medium do not change with age (2000) (17)
- The negative impact of single prolonged stress (SPS) on bone development in mice (2013) (17)
- Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells. (1997) (17)
- Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis. (2008) (17)
- A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes. (2003) (17)
- A Genomic Imprinting Defect in Mice Traced to a Single Gene (2010) (17)
- Localization of the IGF binding domain and evaluation of the role of cysteine residues in IGF binding in IGF binding protein-4. (2001) (16)
- Longitudinal In Vivo Effects of Growth Hormone Overexpression on Bone in Transgenic Mice (2004) (16)
- Copurification of osteolytic and transforming growth factor beta activities produced by human lung tumor cells associated with humoral hypercalcemia of malignancy. (1989) (16)
- Evidence that human bone cells in culture contain binding sites for osteogenic protein-1. (1994) (16)
- Emerging multifunctional roles of Claudin tight junction proteins in bone. (2014) (16)
- Sequence comparison and predicted structure for the four exon-encoded regions of human insulin-like growth factor binding protein 4. (1995) (16)
- Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ × SJL/J inbred mice Published, JLR Papers in Press, October 27, 2005. (2006) (16)
- Development and Application of a Synthetic Peptide-Based Osteocalcin Assay for the Measurement of Bone Formation in Mouse Serum (2000) (16)
- Duffy Antigen Receptor for Chemokines Regulates Post-Fracture Inflammation (2013) (16)
- Lmx1b-targeted cis-regulatory modules involved in limb dorsalization (2017) (15)
- The role of IGF system in the rise and fall in bone density with age. (2007) (15)
- Thyroid hormone acting via TRβ induces expression of browning genes in mouse bone marrow adipose tissue (2017) (15)
- Purification and N-terminal amino acid sequence of the tartrate-resistant acid phosphatase from human osteoclastoma: evidence for a single structure. (1990) (15)
- Lasting Consequences of Traumatic Events on Behavioral and Skeletal Parameters in a Mouse Model for Post-Traumatic Stress Disorder (PTSD) (2012) (15)
- Insulin-like growth factor binding protein production in bovine retinal endothelial cells. (1997) (15)
- Conditional Deletion of the Phd2 Gene in Articular Chondrocytes Accelerates Differentiation and Reduces Articular Cartilage Thickness (2017) (14)
- Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice. (2002) (14)
- Detecting Novel Bone Density and Bone Size Quantitative Trait Loci Using a Cross of MRL/MpJ and CAST/EiJ Inbred Mice (2007) (14)
- Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J). (2003) (14)
- Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2 (2019) (14)
- Covalent interaction between proform of eosinophil major basic protein (proMBP) and pregnancy-associated plasma protein-A (PAPP-A) is a cell-mediated event and required for proMBP inhibition of the catalytic activity of PAPP-A. (2004) (14)
- Role and mechanism of action of leucine-rich repeat kinase 1 in bone (2017) (14)
- Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F2 mice (2002) (14)
- Normal growth despite GH, IGF-I and IGF-II deficiency. (1999) (14)
- Differential Expression of Claudin Family Members during Osteoblast and Osteoclast Differentiation: Cldn-1 Is a Novel Positive Regulator of Osteoblastogenesis (2014) (14)
- IGF-I, IGF-II, 'free' IGF-I and IGF-binding proteins-2 to -6 during high-dose oestrogen treatment in constitutionally tall girls. (2002) (14)
- Bone repletion in vitro: evidence for a locally regulated bone repair response to PTH treatment. (1988) (14)
- Effects of Thyroxine (T4), 3,5,3′-triiodo-l-thyronine (T3) and their Metabolites on Osteoblast Differentiation (2016) (14)
- Increased serum concentration of IGFBP-4 and IGFBP-5 in healthy adults during one month's treatment with supraphysiological doses of growth hormone. (2007) (14)
- Characterization of insulin-like growth factor-binding proteins produced by cultured fibroblasts from patients with noninsulin-dependent diabetes mellitus, insulin-dependent diabetes mellitus, or obesity. (1994) (14)
- Identification of Gender-Specific Candidate Genes that Influence Bone Microarchitecture in Chromosome 1 (2013) (13)
- Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children (1999) (13)
- Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation. (2011) (13)
- Mapping genetic loci that regulate lipid levels in a NZB/B1NJ×RF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains Published, JLR Papers in Press, May 13, 2007. (2007) (13)
- Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice (2016) (12)
- Evaluation of IGF System Component Levels and Mitogenic Activity of Uremic Serum on Normal Human Osteoblasts (2000) (12)
- Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ × SJL/J) F2 mice (2002) (12)
- Bone-derived factors active on bone cells (2006) (12)
- Loss of Sex-Specific Difference in Femoral Bone Parameters in Male Leptin Knockout Mice (2007) (12)
- Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation (2016) (11)
- Thyroid hormone receptor-β1 signaling is critically involved in regulating secondary ossification via promoting transcription of the Ihh gene in the epiphysis. (2016) (11)
- Fibroblast growth factor enhances the transcription and stability of human chorionic gonadotropin beta-subunit messenger ribonucleic acid in Jar choriocarcinoma cells. (1993) (11)
- A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways. (2008) (11)
- Effect of Altering Dietary n-6:n-3 Polyunsaturated Fatty Acid Ratio with Plant and Marine-Based Supplement on Biomarkers of Bone Turnover in Healthy Adults (2017) (11)
- Thyroid Hormone Signaling in the Development of the Endochondral Skeleton. (2018) (10)
- Evidence that tartrate-resistant acid phosphatases from osteoclastomas and hairy cell leukemia spleen are members of a multigene family. (1991) (10)
- CHAPTER 19 – Role of Growth Hormone/Insulin-like Growth Factor Axis (1999) (10)
- Reduced bone mass accrual in mouse model of repetitive mild traumatic brain injury. (2014) (10)
- Novel Role for Claudin‐11 in the Regulation of Osteoblasts via Modulation of ADAM10‐Mediated Notch Signaling (2019) (9)
- Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester. (2004) (9)
- LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L‐plastin (2018) (9)
- Chemical mutagenesis induced two high bone density mouse mutants map to a concordant distal chromosome 4 locus. (2007) (9)
- Bidirectional ephrin signaling in bone (2016) (9)
- Construction of a BAC Contig for a 3 cM Biologically Significant Region of Mouse Chromosome 1 (2004) (9)
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton (2021) (9)
- Opposing Changes in Osteocalcin Levels in Bone vs Serum During the Acquisition of Peak Bone Density in C3H/HeJ and C57BL/6J Mice (2002) (8)
- Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice. (2013) (8)
- Experimental repetitive mild traumatic brain injury induces deficits in trabecular bone microarchitecture and strength in mice (2017) (8)
- Modulation of Cathepsin D Routing by IGF-II Involves IGF-II Binding to IGF-II/M6P Receptor in MCF-7 Breast Cancer Cells (2004) (8)
- Role and mechanism of action of leucine-rich repeat kinase 1 in bone (2017) (8)
- Effects of inhibitors of signal transduction pathways on transforming growth factor B1 and osteogenic protein‐1‐induced insulinlike growth factor binding protein‐3 expression in human bone cells (1997) (8)
- Model-based Comparative Prediction of Transcription-Factor Binding Motifs in Anabolic Responses in Bone (2008) (7)
- Marrow Stromal Cell-Based Cyclooxygenase 2 Ex Vivo Gene-Transfer Strategy Surprisingly Lacks Bone-Regeneration Effects and Suppresses the Bone-Regeneration Action of Bone Morphogenetic Protein 4 in a Mouse Critical-Sized Calvarial Defect Model (2009) (7)
- Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: Congenic analysis and fine mapping (2007) (7)
- Stem cell antigen‐1+ cell‐based bone morphogenetic protein‐4 gene transfer strategy in mice failed to promote endosteal bone formation (2009) (7)
- Effect of type of dialysis membrane on bone in haemodialysis patients. (2001) (7)
- Cortical and trabecular bone are equally affected in rats with renal failure and secondary hyperparathyroidism (2018) (7)
- Identification and characterization of novel IGFBP5 interacting protein: evidence IGFBP5-IP is a potential regulator of osteoblast cell proliferation. (2006) (7)
- Bone density phenotypes in mice aneuploid for the Down syndrome critical region (2011) (7)
- Application of Genomic Resources and Gene Expression Profiles to Identify Genes That Regulate Bone Density (2003) (6)
- Structural and functional analysis of the 5'-flanking region of the human insulin-like growth factor binding protein (IGFBP)-4 gene. (1997) (6)
- Sca-1(+) hematopoietic cell-based gene therapy with a modified FGF-2 increased endosteal/trabecular bone formation in mice. (2007) (6)
- A high‐calcium diet failed to rescue an osteopenia phenotype in claudin‐18 knockout mice (2014) (6)
- Changes in ephrin gene expression during bone healing identify a restricted repertoire of ephrins mediating fracture repair (2018) (6)
- Erythrocyte insulin‐like growth factor‐I binding in younger and older males (1996) (6)
- Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice (2018) (6)
- RE1‐Silencing Transcription Factor (Rest) is a Novel Regulator of Osteoblast Differentiation (2015) (5)
- CCN1/Cyr61 Is Required in Osteoblasts for Responsiveness to the Anabolic Activity of PTH (2020) (5)
- Growth Hormone Effects on Bone Loss-Induced by Mild Traumatic Brain Injury and/or Hind Limb Unloading (2019) (5)
- Quantitation of growth factors in ossein-mineral-compound. (1991) (5)
- Chemokine receptor 3 is a negative regulator of trabecular bone mass in female mice (2019) (5)
- Stem cell antigen‐1 positive cell‐based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice (2011) (5)
- A small molecular inhibitor of LRRK1 identified by homology modeling and virtual screening suppresses osteoclast function, but not osteoclast differentiation, in vitro (2019) (5)
- Low IGF-I in synovial fluid and serum in patients with aseptic prosthesis loosening (2005) (5)
- Ras-Association Domain Family 1c protein enhances Breast Tumor Growth In Vivo (2012) (5)
- The mechanism by which IGFBP-5 exerts anabolic effects in bone. (2000) (5)
- BEYOND CARRIER PROTEINS IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms (2002) (4)
- [27] Purification of bovine skeletal growth factor (1987) (4)
- Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene (2008) (4)
- The Cytoplasmic Dynein Associated Protein NDE1 Regulates Osteoclastogenesis by Modulating M-CSF and RANKL Signaling Pathways (2021) (4)
- In vivo evidence of IGF-I–estrogen crosstalk in mediating the cortical bone response to mechanical strain (2014) (4)
- Homozygous and heterozygous expression of a novel IGF-I mutation 6 (2007) (4)
- Effect of progesterone on the mRNA levels of insulin-like-growth factors (IGFs), IGF-binding proteins (JGFBPs) and type-1 and -type-2 igfreceptors in human osteoblastic cells (1992) (3)
- The effects of the insulin-like growth factors and transforming growth factor beta on the Jun proto-oncogene family in MC3T3-E1 cells. (1994) (3)
- A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing (2020) (3)
- Mapping of the chromosome 17 BMD QTL in the F2 male mice of MRL/MpJ × SJL/J (2008) (3)
- Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #A/J/NaJ chromosome substitution strains. (2008) (3)
- Faculty Opinions recommendation of Coupling of bone resorption and formation by RANKL reverse signalling. (2018) (3)
- Parathyroid hormone-related protein: Primary osteolytic factor produced by breast tumor cells in vitro? (1995) (3)
- The IGF/IGFBP system in relation to macroscopic bone architecture in pediatric renal transplant patients (2010) (3)
- Differences in exposure to stimulatory and inhibitory components of the insulin-like growth factor (IGF) system in patients with femoral neck versus trochanteric fracture. (2005) (3)
- The effects of the insulin-like growth factors and transforming growth factor β on the jun proto-oncogene family in MC3T3-E1 cells (1994) (3)
- Identification of Gender-Specific Candidate Genes that Influence Bone Microarchitecture in Chromosome 1 (2012) (2)
- A Correction: Inhibitory Activity in the Conditioned Medium of Embryonic Chick Bones Is Due to Thymidine (1984) (2)
- Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor −/− mice. (2000) (2)
- Concurrent Anabolic and Catabolic-type Adaptations to Exercise Training in Adolescent Males. 381 (1997) (2)
- A platform of high-efficiency nonviral gene transfer in mouse osteoblast cells in vitro (2006) (2)
- Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regeneration in the injured muscle. (2012) (2)
- Purification of bovine skeletal growth factor. (1987) (2)
- 1.25-Dihydroxyvitamin D3 increases secretion of inhibitory insulin-like growth factor binding protein-4 and inhibits mitogenesis in osteoblastic cells (1992) (2)
- Estrogen receptors in the regulation of skeletal maturation and the GH/IGF-I axis in male mice. (2000) (2)
- and width in mice I collagen-expressing cells reduces bone length α type II Disruption of insulin-like growth factor-I expression in (2015) (2)
- A simple and efficient scheme for the purification of insulin-like growth factor II from human bone matrix extract. (1990) (2)
- Differences in pathways contributing to thyroid hormone effects on postnatal cartilage calcification versus secondary ossification center development (2022) (2)
- Targeted Deletion of the Claudin12 Gene in Mice Increases Articular Cartilage and Inhibits Chondrocyte Differentiation (2022) (2)
- Prolyl Hydroxylase Domain-Containing Protein 3 Gene Expression in Chondrocytes Is Not Essential for Bone Development in Mice (2021) (2)
- Skeletal effects of nongenomic thyroid hormone receptor beta signaling. (2019) (2)
- T-cell factor (TCF) 7L2 is a novel regulator of osteoblast functions that acts in part by modulation of hypoxia (Hif1α) signaling. (2022) (1)
- Effect of n‐3 polyunsaturated fatty acids on peroxisome proliferator‐activated receptor gamma (PPARγ) expression in adults (2012) (1)
- RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1 (2012) (1)
- Monocyte Chemotactic Proteins Mediate the Effects of Hyperglycemia in Chondrocytes: In Vitro Studies (2022) (1)
- Effect of plant and marine sources of n‐3 fatty acids on markers of bone turnover in healthy adults (2010) (1)
- The effect of altering n‐6: n‐3 ratio using plant and marine sources of n‐3 fatty acids on biomarkers of bone turnover (2010) (1)
- Faculty Opinions recommendation of Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease. (2019) (1)
- Lack of Skeletal Effects in Mice with Targeted Disruptionof Prolyl Hydroxylase Domain 1 (Phd1) Gene Expressed in Chondrocytes (2022) (1)
- Preliminary Results of the Antineoplastic Activity of a Marine Terpenoid in Human Cancer Cell Lines (2000) (1)
- [Autocrine regulation of cell proliferation and secretion of insulin-like growth factor I (IGF-I) in osteoblastic cell line MC3T3-E1]. (1994) (1)
- Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women 1 – 3 (1)
- Mice with Targeted Knockout of Tetraspanin 3 Exhibit Reduced Trabecular Bone Mass Caused by Decreased Osteoblast Functions (2022) (1)
- Osteolytic activity of human breast tumor cell lines (1993) (1)
- Repeated mild traumatic brain injury impairs fracture healing in male mice (2022) (1)
- Targeted Disruption of TGFBI in Mice Reveals Its Role in Regulating Bone Mass and Bone Size through Periosteal Bone Formation (2012) (1)
- Opposing Effects of Sca-1+ Cell-Based Systemic FGF-2 Gene Transfer Strategy on Lumbar versus Caudal Vertebrae in the Mouse (2016) (1)
- Development of nonviral basic FGF expression plasmids for ex vivo gene therapy of bone (1999) (1)
- Faculty Opinions recommendation of NOTCH signaling in skeletal progenitors is critical for fracture repair. (2016) (0)
- Faculty Opinions recommendation of Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. (2009) (0)
- Repeated mild traumatic brain injury impairs fracture healing in male mice (2022) (0)
- Faculty of 1000 evaluation for Epitope-specific monoclonal antibodies to FSHβ increase bone mass. (2018) (0)
- metabolismand exercise training on bone Interaction of the effects between vitamin D receptor (2015) (0)
- OR06-1 CRE/LOXP-MEDIATED INACTIVATION OF IGF-I GENE IN TYPE I COLLAGEN EXPRESSING CELLS PRODUCES NEONATAL LETHALITY AND A DRAMATIC EFFECT ON SKELETAL PHENOTYPE (2006) (0)
- EVIDENCE OF A ROLE FOR VITAMIN D AND TRANSFORMING GROWTH FACTOR P IN OSTEOINDUCTION (1991) (0)
- Faculty Opinions recommendation of B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation. (2018) (0)
- Endocrine and Metabolic Dysfunction During Aging and Senescence Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC 1 / Cdc 42 Small GTPase phosphorylation and activation (2016) (0)
- In Vivo Regulation of Insulin-like Growth Factor Binding Proteins -3, -4 and-5 and the Acid Labile Subunit by Growth Hormone in GH-Deficient Patients but not by IGF-I in GH-Insensitive Patients • 405 (1998) (0)
- Faculty Opinions recommendation of Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling. (2011) (0)
- changes are different in two inbred mouse strains Mechanical loading-induced gene expression and BMD (2015) (0)
- Faculty Opinions recommendation of Inhibition of fetal bone development through epigenetic down-regulation of HoxA10 in obese rats fed high-fat diet. (2011) (0)
- Role of Insulin-Like Growth Factor Binding Proteins and Their Proteases (1997) (0)
- Growth Hormone Axis-Independent Growth. A Case Report 438 (1998) (0)
- Humoral Hypercalcemia of Malignancy Activities Produced by Human Lung Tumor Cells Associated β Copurification of Osteolytic and Transforming Growth Factor Updated (2006) (0)
- ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size. (2013) (0)
- The Insulin-like Growth Factor Axis and Prostate Cancer : Lessons from the Transgenic Adenocarcinoma of Mouse Prostate ( TRAMP ) Model 1 (2000) (0)
- Coupling of Bone Formation and Bone Resorption: A Model (1998) (0)
- Molecular Mechanisms of Soft Tissue Regeneration and Bone Formation in Mice: Implications in Fracture Repair and Wound Healing in Humans (2006) (0)
- Evidence for the elaboration of a non-parathormone related protein osteolytic factor from human breast tumor cell lines (1993) (0)
- Decision letter: Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix (2020) (0)
- Erratum to “Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor −/− mice” [Biochem. Biophys. Res. Commun. 267 (2000) 603–608] (2006) (0)
- Growth factors: Potential treatment of osteoporosis (1995) (0)
- Seasonal Changes in the IGF Regulatory System and The Relationship to Bone Loss in Elderly Women (2002) (0)
- Faculty Opinions recommendation of Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time. (2019) (0)
- Possible Link Between Estrogen Levels, Estrogen Receptors and the Tumor Suppressor Gene p53 During Gestation in Rat Placenta (2009) (0)
- Differential activation of nuclear factor‐kappa B in healing tissue of poor healer SJL strain and good healer MRL strain: Implications in wound repair and regeneration (2006) (0)
- Faculty Opinions recommendation of Secondary ossification center induces and protects growth plate structure. (2020) (0)
- The Role of Insulin-Like Growth Factor Binding Protein-5 in Bone (1997) (0)
- Faculty Opinions recommendation of Targeting skeletal endothelium to ameliorate bone loss. (2018) (0)
- Molecular Genetic and Gene Therapy Studies of the Musculoskeletal System (2004) (0)
- Evidence that second messenger responses are differentiation stage dependent (1993) (0)
- 449. Sca-1+ Cell-Based Gene Therapy with a Modified Fibroblast Growth Factor 2 (FGF2) Increased Endosteal/Trabecular Bone Formation in Mice (2006) (0)
- Effects of insulin like growth factors I & II on cell activity and calcitriol receptor levels in human bone cells in vitro (1995) (0)
- Leucine Repeat Rich Kinase 1 Controls Osteoclast Activity by Managing Lysosomal Trafficking and Secretion (2023) (0)
- WNT16 Regulation of the Articular Chondrocyte Phenotype in Mice (2023) (0)
- Sequential application of small molecule therapy enhances chondrogenesis and angiogenesis in murine segmental defect bone repair. (2022) (0)
- Placental Inactivity of an Imprinted Gene Underlies Midgestation Death of Mice With Paternal Duplication of Distal Chromosome 7 (2010) (0)
- Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation (2017) (0)
- Development of an Animal Model for Traumatic Brain Injury Augmentation of Heterotopic Ossification in Response to Local Injury (2023) (0)
- Faculty Opinions recommendation of The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. (2010) (0)
- TITLE: Molecular Genetic Studies of Bone Mechanical Strain and of Pedigrees with Very High Bone Density PRINCIPAL INVESTIGATOR: Subburaman Mohan, Ph.D. CONTRACTING ORGANIZATION: Loma Linda Veterans Association for Research and Education (2006) (0)
- Computational prediction of small molecules with predicted binding to FGFR3 and testing biological effects in bone cells (2021) (0)
- 1 Pre-pubertal OVX increases IGF-I expression and bone accretion in C 57 BL / 6 J mice Short Title : Estrogen effects on IGF-I and bone during puberty (2008) (0)
- Faculty Opinions recommendation of Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. (2019) (0)
- Vitamin C Deficiency–Induced Hearing Loss and Ossicular Defect in Transgenic Mice (2013) (0)
- Changes in ephrin gene expression during bone healing identify a restricted repertoire of ephrins mediating fracture repair (2018) (0)
- The serum concentration of insulin-like growth factor binding protein-5 (IGFBP-5) is related to vitamin D status in patients with osteoporosis (1995) (0)
- Faculty Opinions recommendation of Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure. (2020) (0)
- HDL cholesterol in SM/J and NZB/B1NJ inbred mice Quantitative trait locus mapping of genes that regulate (2015) (0)
- pathwayediated proteosomal degradation osteoblasts by activation of prolyl hydroxylase and Ascorbic acid regulates osterix expression in (2015) (0)
- Faculty Opinions recommendation of ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. (2011) (0)
- Vitamin C Deficiency Impairs Mineralization of Ossicle in Mice (2014) (0)
- Effects of Thyroxine (T4), 3,5,3′-triiodo-l-thyronine (T3) and their Metabolites on Osteoblast Differentiation (2016) (0)
- A process for the release of ligand-binding proteins (1994) (0)
- Faculty Opinions recommendation of The HIF-PHI BAY 85-3934 (Molidustat) improves anemia and is associated with reduced levels of circulating FGF23 in a CKD mouse model. (2021) (0)
- Faculty Opinions recommendation of Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption. (2021) (0)
- Molecular Genetic Studies of Bone Mechanical Strain and of Pedigrees With Very High Bone Density (2005) (0)
- Growth hormone axis-independent growth (1998) (0)
- OR5,27 A novel approach involving a sensitized chemical mutagenesis screen to identify genes that interact with GH signaling pathway to regulate skeletal phenotype (2010) (0)
- Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity (2022) (0)
- gallstones in AKR/J and C57L/J strains of mice Quantitative trait loci mapping for cholesterol (2015) (0)
- Riddle of estrogen regulation of IGF-I action and periosteal bone formation (2006) (0)
- 038 Digit Tip Regeneration and Global Gene Expression Profiling in the MRL SuperHealer Mouse (2008) (0)
- Genetic Knockout and Rescue Studies in Mice Unravel Abnormal Phosphorus Threshold in Hypophosphatemic Rickets (2017) (0)
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What Schools Are Affiliated With Subburaman Mohan?
Subburaman Mohan is affiliated with the following schools:
