Sulayman Daoud Dib-hajj
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Sulayman Daoud Dib-hajj's Degrees
- Masters Biology Stanford University
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(Suggest an Edit or Addition)Sulayman Daoud Dib-hajj's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sodium channels in normal and pathological pain. (2010) (543)
- NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy. (1998) (502)
- A Novel Persistent Tetrodotoxin-Resistant Sodium Current In SNS-Null And Wild-Type Small Primary Sensory Neurons (1999) (454)
- The NaV1.7 sodium channel: from molecule to man (2012) (450)
- Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. (2005) (413)
- Sodium channels and pain. (1999) (407)
- Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy (2012) (394)
- A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. (2006) (369)
- Gain-of-function Nav1.8 mutations in painful neuropathy (2012) (362)
- De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP. (2012) (356)
- Electrophysiological Properties of Mutant Nav1.7 Sodium Channels in a Painful Inherited Neuropathy (2004) (350)
- Spinal sensory neurons express multiple sodium channel α-subunit mRNAs (1996) (337)
- Distinct repriming and closed‐state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons (2003) (303)
- Sodium channel α-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): Different expression patterns in developing rat nervous system (1997) (301)
- Nav1.3 Sodium Channels: Rapid Repriming and Slow Closed-State Inactivation Display Quantitative Differences after Expression in a Mammalian Cell Line and in Spinal Sensory Neurons (2001) (300)
- The Role of Voltage-Gated Sodium Channels in Pain Signaling. (2019) (286)
- Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain (1999) (277)
- Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones (2005) (272)
- From genes to pain: Nav1.7 and human pain disorders (2007) (249)
- NaN/Nav1.9: a sodium channel with unique properties (2002) (248)
- The Presence and Role of the Tetrodotoxin-Resistant Sodium Channel Nav1.9 (NaN) in Nociceptive Primary Afferent Neurons (2002) (246)
- Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases (2008) (240)
- Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy. (2014) (236)
- SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model (1998) (235)
- Down-Regulation of Transcripts for Na Channel α -SNS in Spinal Sensory Neurons Following Axotomy (1996) (227)
- Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system (2012) (225)
- Changes in Expression of Two Tetrodotoxin-Resistant Sodium Channels and Their Currents in Dorsal Root Ganglion Neurons after Sciatic Nerve Injury But Not Rhizotomy (2000) (209)
- Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons. (1999) (209)
- Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain (1999) (206)
- Voltage-gated sodium channels: therapeutic targets for pain. (2009) (200)
- Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. (1998) (181)
- A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity (2007) (166)
- Phosphorylation of Sodium Channel Nav1.8 by p38 Mitogen-Activated Protein Kinase Increases Current Density in Dorsal Root Ganglion Neurons (2008) (165)
- Sporadic onset of erythermalgia: A gain‐of‐function mutation in Nav1.7 (2006) (163)
- Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: Evidence for a role in pain (2008) (163)
- NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders (2008) (161)
- Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn (2012) (160)
- Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. (1996) (156)
- ERK1/2 Mitogen-Activated Protein Kinase Phosphorylates Sodium Channel Nav1.7 and Alters Its Gating Properties (2010) (155)
- Modulation of the Cardiac Sodium Channel Nav1.5 by Fibroblast Growth Factor Homologous Factor 1B* (2003) (155)
- Sodium channel genes in pain-related disorders: phenotype–genotype associations and recommendations for clinical use (2014) (152)
- Glial-Derived Neurotrophic Factor Upregulates Expression of Functional SNS and NaN Sodium Channels and Their Currents in Axotomized Dorsal Root Ganglion Neurons (2000) (148)
- NaV1.9: a sodium channel linked to human pain (2015) (147)
- Destruction of paranodal architecture in inflammatory neuropathy with anti-contactin-1 autoantibodies (2015) (146)
- Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. (1997) (146)
- Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis (2009) (144)
- Two tetrodotoxin‐resistant sodium channels in human dorsal root ganglion neurons (1999) (141)
- Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment (2009) (136)
- Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release (2016) (134)
- Erythermalgia: molecular basis for an inherited pain syndrome. (2005) (133)
- NGF has opposing effects on Na+ channel III and SNS gene expression in spinal sensory neurons (1997) (132)
- Fibroblast Growth Factor Homologous Factor 2B: Association with Nav1.6 and Selective Colocalization at Nodes of Ranvier of Dorsal Root Axons (2004) (132)
- Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis. (2000) (129)
- Localization of the tetrodotoxin‐resistant sodium channel NaN in nociceptors (2000) (127)
- A novel Nav1.7 mutation producing carbamazepine‐responsive erythromelalgia (2009) (126)
- Nav1.7 Mutant A863P in Erythromelalgia: Effects of Altered Activation and Steady-State Inactivation on Excitability of Nociceptive Dorsal Root Ganglion Neurons (2006) (124)
- Expression of the Voltage-Gated Sodium Channel NaV1.5 in the Macrophage Late Endosome Regulates Endosomal Acidification1 (2007) (121)
- Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable (2008) (118)
- Fibroblast Growth Factor Homologous Factor 1B Binds to the C Terminus of the Tetrodotoxin-resistant Sodium Channel rNav1.9a (NaN)* (2001) (117)
- Transfection of rat or mouse neurons by biolistics or electroporation (2009) (114)
- An AnkyrinG-Binding Motif Is Necessary and Sufficient for Targeting Nav1.6 Sodium Channels to Axon Initial Segments and Nodes of Ranvier (2012) (113)
- Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a (2017) (112)
- Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons (2005) (112)
- De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy (2015) (110)
- Voltage-Gated Sodium Channel Nav1.6 Is Modulated by p38 Mitogen-Activated Protein Kinase (2005) (110)
- Glycosylation Alters Steady-State Inactivation of Sodium Channel Nav1.9/NaN in Dorsal Root Ganglion Neurons and Is Developmentally Regulated (2001) (109)
- FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels (2009) (106)
- Mutation I136V alters electrophysiological properties of the NaV1.7 channel in a family with onset of erythromelalgia in the second decade (2008) (105)
- Voltage-clamp and current-clamp recordings from mammalian DRG neurons (2009) (104)
- Intra- and interfamily phenotypic diversity in pain syndromes associated with a gain-of-function variant of NaV1.7 (2011) (103)
- Early- and late-onset inherited erythromelalgia: genotype-phenotype correlation. (2009) (103)
- GDNF and NGF reverse changes in repriming of TTX-sensitive Na(+) currents following axotomy of dorsal root ganglion neurons. (2002) (101)
- Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy. (2012) (99)
- Sodium channels and their genes: dynamic expression in the normal nervous system, dysregulation in disease states 1 1 Published on the World Wide Web on 15 August 2000. (2000) (98)
- Small-Fiber Neuropathy Nav1.8 Mutation Shifts Activation to Hyperpolarized Potentials and Increases Excitability of Dorsal Root Ganglion Neurons (2013) (97)
- Group II introns deleted for multiple substructures retain self-splicing activity. (1992) (96)
- Voltage-gated sodium channels and the molecular pathogenesis of pain: a review. (2000) (96)
- A sodium channel gene SCN9A polymorphism that increases nociceptor excitability (2009) (93)
- A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy (2014) (92)
- A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons (2010) (86)
- Na(v)1.5 underlies the 'third TTX-R sodium current' in rat small DRG neurons. (2002) (86)
- Novel SCN1A mutation in a proband with malignant migrating partial seizures of infancy. (2011) (86)
- Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy (2014) (86)
- Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel (2012) (84)
- Contactin regulates the current density and axonal expression of tetrodotoxin‐resistant but not tetrodotoxin‐sensitive sodium channels in DRG neurons (2005) (83)
- Direct Interaction with Contactin Targets Voltage-gated Sodium Channel Nav1.9/NaN to the Cell Membrane* (2001) (82)
- A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia (2016) (80)
- Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy. (1996) (79)
- Size Matters: Erythromelalgia Mutation S241T in Nav1.7 Alters Channel Gating* (2006) (78)
- The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability (2013) (78)
- Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons. (2007) (77)
- Mexiletine-responsive erythromelalgia due to a new Nav1.7 mutation showing use-dependent current fall-off (2009) (77)
- Sodium Channel Nav1.7 Is Essential for Lowering Heat Pain Threshold after Burn Injury (2012) (75)
- Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue (2005) (75)
- Screening Fluorescent Voltage Indicators with Spontaneously Spiking HEK Cells (2013) (75)
- Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron (1995) (75)
- Differential modulation of sodium channel Nav1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily (2006) (75)
- Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons. (2015) (73)
- Virus-mediated shRNA knockdown of Na(v)1.3 in rat dorsal root ganglion attenuates nerve injury-induced neuropathic pain. (2013) (72)
- Deletion mutation of sodium channel Na(V)1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability. (2011) (72)
- Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. (2016) (72)
- Small nerve fibres, small hands and small feet: a new syndrome of pain, dysautonomia and acromesomelia in a kindred with a novel NaV1.7 mutation. (2012) (71)
- Erythromelalgia: A hereditary pain syndrome enters the molecular era (2005) (69)
- Nav1.7-related small fiber neuropathy (2012) (68)
- Genetics and molecular pathophysiology of Na(v)1.7-related pain syndromes. (2008) (67)
- The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy (2015) (67)
- Lacosamide in patients with Nav1.7 mutations-related small fibre neuropathy: a randomized controlled trial (2019) (67)
- Polydnavirus-facilitated endoparasite protection against host immune defenses. (1995) (64)
- Abnormal expression of SNS/PN3 sodium channel in cerebellar Purkinje cells following loss of myelin in the taiep rat. (1999) (63)
- Sodium Channels in Human Pain Disorders: Genetics and Pharmacogenomics. (2019) (63)
- Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons (2011) (63)
- Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile. (2016) (62)
- Inherited erythermalgia (2006) (62)
- Structure and evolutionary implications of a "cysteine-rich" Campoletis sonorensis polydnavirus gene family. (1993) (62)
- Contactin Associates with Sodium Channel Nav1.3 in Native Tissues and Increases Channel Density at the Cell Surface (2004) (61)
- Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia. (2010) (60)
- Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain (2018) (59)
- Virus-Mediated Knockdown of Nav1.3 in Dorsal Root Ganglia of STZ-Induced Diabetic Rats Alleviates Tactile Allodynia (2015) (58)
- Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons (2011) (57)
- Sodium channels in pain disorders: pathophysiology and prospects for treatment (2017) (57)
- Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN. (1999) (56)
- Patterned electrical activity modulates sodium channel expression in sensory neurons (2003) (56)
- Dynamic-clamp analysis of wild-type human Nav1.7 and erythromelalgia mutant channel L858H. (2014) (56)
- Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability (2017) (55)
- Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli (2016) (54)
- Tetrodotoxin-sensitive Na+ channels and muscarinic and purinergic receptors identified in human erythroid progenitor cells and red blood cell ghosts. (2004) (52)
- Sodium channels and the molecular pathophysiology of pain. (2000) (51)
- Two Nedd4-binding Motifs Underlie Modulation of Sodium Channel Nav1.6 by p38 MAPK* (2010) (50)
- The ataxia3 Mutation in the N-Terminal Cytoplasmic Domain of Sodium Channel Nav1.6 Disrupts Intracellular Trafficking (2009) (50)
- Resilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp (2018) (50)
- Familial gain-of-function Nav1.9 mutation in a painful channelopathy (2016) (49)
- Preferential Targeting of Nav1.6 Voltage-Gated Na+ Channels to the Axon Initial Segment during Development (2015) (48)
- NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine. (2018) (48)
- A new Nav1.7 sodium channel mutation I234T in a child with severe pain (2010) (47)
- Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. (2006) (47)
- Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability (2010) (47)
- Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7 (2007) (46)
- Translational pain research: Lessons from genetics and genomics (2014) (44)
- Insertion of a SNS‐specific tetrapeptide in S3–S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage‐gated Na channel μ1 in HEK293 cells (1997) (44)
- Differential expression of sodium channel genes in retinal ganglion cells. (1997) (44)
- Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia (2013) (42)
- A Pore-blocking Hydrophobic Motif at the Cytoplasmic Aperture of the Closed-state Nav1.7 Channel Is Disrupted by the Erythromelalgia-associated F1449V Mutation* (2008) (41)
- Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes (1998) (40)
- PKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice. (2012) (40)
- A channelopathy contributes to cerebellar dysfunction in a model of multiple sclerosis (2012) (38)
- Critical molecular determinants of voltage-gated sodium channel sensitivity to mu-conotoxins GIIIA/B. (2002) (38)
- CAP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Nav1.8 (2005) (38)
- Can robots patch‐clamp as well as humans? Characterization of a novel sodium channel mutation (2010) (38)
- Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel NaV1.7 produce distinct pain disorders (2010) (35)
- Virus-mediated shRNA Knockdown of Nav1.3 in Rat Dorsal Root Ganglion Attenuates Nerve Injury-induced Neuropathic Pain. (2013) (35)
- Multistate Structural Modeling and Voltage-Clamp Analysis of Epilepsy/Autism Mutation Kv10.2–R327H Demonstrate the Role of This Residue in Stabilizing the Channel Closed State (2013) (34)
- Interaction of Voltage-gated Sodium Channel Nav1.6 (SCN8A) with Microtubule-associated Protein Map1b* (2012) (32)
- A case of inherited erythromelalgia (2007) (32)
- A UV-induced, Mg(2+)-dependent crosslink traps an active form of domain 3 of a self-splicing group II intron. (1995) (31)
- Diverse functions and dynamic expression of neuronal sodium channels. (2002) (31)
- A SCN10A SNP biases human pain sensitivity (2016) (31)
- Characterization of small fiber pathology in a mouse model of Fabry disease (2018) (30)
- A gain-of-function sodium channel β2-subunit mutation in painful diabetic neuropathy (2019) (29)
- Schwann cells modulate sodium channel expression in spinal sensory neurons in vitro (1997) (29)
- Differential effect of lacosamide on Nav1.7 variants from responsive and non-responsive patients with small fibre neuropathy (2020) (29)
- COL6A5 variants in familial neuropathic chronic itch (2017) (29)
- Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators (2019) (28)
- Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials. (2009) (28)
- Network topology of NaV1.7 mutations in sodium channel-related painful disorders (2017) (28)
- Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing. (1993) (27)
- Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav1.7 mutation I234T (2018) (26)
- Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties (2010) (26)
- Functional role of the C‐terminus of voltage‐gated sodium channel Nav1.8 (2004) (25)
- Genes encoding the β1 subunit of voltage‐dependent Na+ channel in rat, mouse and human contain conserved introns (1995) (25)
- Familial trigeminal neuralgia – a systematic clinical study with a genomic screen of the neuronal electrogenisome (2020) (25)
- Paclitaxel increases axonal localization and vesicular trafficking of Nav1.7 (2021) (23)
- A new Nav1.7 mutation in an erythromelalgia patient. (2013) (23)
- NaV1.6 regulates excitability of mechanosensitive sensory neurons (2019) (22)
- Characterization and developmental changes of Na+ currents of petrosal neurons with projections to the carotid body. (2002) (22)
- Sodium channel mRNA in the B104 neuroblastoma cell line (1996) (22)
- Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a (2017) (21)
- Physiological and genetic analysis of multiple sodium channel variants in a model of genetic absence epilepsy (2014) (21)
- Molecular Architecture of a Sodium Channel S6 Helix (2013) (21)
- The pentapeptide QYNAD does not block voltage-gated sodium channels (2003) (21)
- TTX-sensitive and -resistant Na+ currents, and mRNA for the TTX-resistant rH1 channel, are expressed in B104 neuroblastoma cells. (1997) (21)
- NaG: A sodium channel‐like mRNA shared by Schwann cells and other neural crest derivatives (1997) (20)
- Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy (2015) (20)
- Expression of skeletal muscle‐type voltage‐gated Na+ channel in rat and human prostate cancer cell lines (1998) (20)
- Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder (2016) (20)
- Molecular determinant of Nav1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeus (2002) (19)
- Oral Administration of PF-01247324, a Subtype-Selective Nav1.8 Blocker, Reverses Cerebellar Deficits in a Mouse Model of Multiple Sclerosis (2015) (19)
- Sodium channel Nav1.6 in sensory neurons contributes to vincristine-induced allodynia. (2020) (19)
- A Novel Gain-of-Function Nav1.9 Mutation in a Child With Episodic Pain (2019) (19)
- Depolarized Inactivation Overcomes Impaired Activation to Produce DRG Neuron Hyperexcitability in a Nav1.7 Mutation in a Patient with Distal Limb Pain (2014) (18)
- Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models. (2019) (18)
- Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia (2020) (18)
- The Novel Activity of Carbamazepine as an Activation Modulator Extends from NaV1.7 Mutations to the NaV1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy (2018) (18)
- Differential effect of D623N variant and wild-type Nav1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons (2013) (17)
- Neuropathic pain in two-generation twins carrying the sodium channel Nav1.7 functional variant R1150W (2014) (17)
- Mutations in the sodium channel Nav1.7 underlie inherited erythromelalgia (2006) (16)
- Pediatric Erythromelalgia and SCN9A Mutations: Systematic Review and Single‐Center Case Series (2019) (15)
- The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development (2017) (15)
- Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus (2014) (15)
- Gain-of-function mutation of a voltage-gated sodium channel NaV1.7 associated with peripheral pain and impaired limb development (2017) (15)
- SCN9A-Related Inherited Erythromelalgia (2013) (14)
- Structure of the sodium channel gene SCN11A (2002) (14)
- Pharmacological characterization of a rat Nav1.7 loss-of-function model with insensitivity to pain. (2020) (13)
- Somatosensory Neurons Enter a State of Altered Excitability during Hibernation (2018) (13)
- Diversity of composition and function of sodium channels in peripheral sensory neurons. (2015) (12)
- Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner (2019) (12)
- Evaluation of molecular inversion probe versus TruSeq® custom methods for targeted next-generation sequencing (2020) (12)
- Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner (2018) (11)
- Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation (2018) (11)
- Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability (2022) (10)
- Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits (2018) (10)
- A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane (2019) (9)
- The Two Sides of NaV1.7: Painful and Painless Channelopathies (2019) (9)
- KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience (2021) (9)
- Mini-review - Sodium channels and beyond in peripheral nerve disease: Modulation by cytokines and their effector protein kinases (2020) (9)
- β1 adducin gene expression in DRG is developmentally regulated and is upregulated by glial-derived neurotrophic factor and nerve growth factor (2001) (7)
- Therapeutic potential of Pak1 inhibition for pain associated with cutaneous burn injury (2018) (7)
- A novel gain-of-function Nav1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy (2018) (7)
- Dynamic-clamp Analysis of Wild-type hNaV1.7 and Erythromelalgia Mutant Channel (2013) (6)
- Group II introns deleted for multiple substructures retain self-splicing activity (1992) (6)
- Nonmuscle myosin II isoforms interact with sodium channel alpha subunits (2018) (6)
- Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease (2018) (6)
- DNA sequence organization in the genome of Cycas revoluta (1983) (5)
- Human pain in a dish: Native DRG neurons and differentiated pluripotent stem cells (2014) (5)
- Sodium channels and the molecular basis for pain (2002) (4)
- Voltage-gated sodium channels (2009) (4)
- Depolarizing NaV and Hyperpolarizing KV Channels Are Co-Trafficked in Sensory Neurons (2022) (4)
- Differential aging‐related changes in neurophysiology and gene expression in IB4‐positive and IB4‐negative nociceptive neurons (2018) (4)
- Molecular Contactin Associates with Sodium Channel Nav 1 . 3 in Native Tissues and Increases Channel Density at the Cell Surface (2004) (4)
- A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons (2022) (4)
- Mexiletine-responsive Erythromelalgia Due To A New NaV1.7 Mutation Showing Use-dependent Block (2009) (3)
- Lacosamide Inhibition of NaV1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore (2021) (3)
- SCN9A Neuropathic Pain Syndromes (1993) (3)
- Trigeminal Neuralgia TRPM8 Mutation (2021) (3)
- Beta1 adducin gene expression in DRG is developmentally regulated and is upregulated by glial-derived neurotrophic factor and nerve growth factor. (2001) (3)
- 293 SPONTANEOUS IMPULSE GENERATION IN C‐NOCICEPTORS OF FAMILIAL ERYTHROMELALGIA (FE) PATIENTS (2007) (2)
- In vitro studies of domains 1, 3 and 5 of self-splicing group II introns of yeast mtDNA / (1990) (2)
- Maximizing treatment efficacy through patient stratification in neuropathic pain trials (2022) (2)
- The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation (2022) (1)
- 46 PHOSPHORYLATION OF SODIUM CHANNEL NAV1.8 BY P38 MAPK INCREASES CURRENT DENSITY IN DRG NEURONS (2007) (1)
- Voltage-gated sodium channels and pain associated with nerve injury and neuropathies (2005) (1)
- Novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type spinal sensory neurons (2000) (1)
- Correction: Contactin-1 and Neurofascin-155/-186 Are Not Targets of Auto-Antibodies in Multifocal Motor Neuropathy (2015) (1)
- iFGF14-Navs: A monogamous partnership? (2016) (1)
- Pharmacological activity and NMR solution structure of the leech peptide HSTX-I. (2020) (1)
- Inhibition of sodium conductance by cannabigerol contributes to a reduction of neuronal dorsal root ganglion excitability (2021) (1)
- Molecular architecture of a sodium channel S 6 helix : radial tuning of the Nav 1 . 7 activation gate (2013) (1)
- Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity. (2023) (1)
- Physiological and genetic analysis of multiple sodium channel variants in a model of genetic (2014) (0)
- A novel high throughput combined voltage-clamp/current-clamp analysis of single primary neurons. (2023) (0)
- Voltage‐Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain (2008) (0)
- Analysis of Voltage-Gated Sodium Channel Membrane Dynamics in Hippocampal Neurons via a Fluorescent Protein and Biotin Tagged Nav1.6 Channel (2012) (0)
- Altered Axonal Trafficking of NaV1.7 in Cultured Peripheral Neurons in Response to Inflammatory Mediators and Paclitaxel (2020) (0)
- Fibroblast Growth Factor Homologous Factor 2 attenuates excitability of DRG neurons. (2022) (0)
- Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease (2018) (0)
- Paclitaxel effects on axonal localization and vesicular trafficking of NaV1.8 (2023) (0)
- Author response: Characterization of small fiber pathology in a mouse model of Fabry disease (2018) (0)
- A Buthus martensii Karsch scorpion sting targets Nav1.7 in mice and mimics a phenotype of human chronic pain. (2021) (0)
- Voltage-Gated Sodium Channels : Therapeutic Targets for Pain pme (2009) (0)
- Endosome Regulates Endosomal Acidification Channel NaV1.5 in the Macrophage Late Expression of the Voltage-Gated Sodium (2007) (0)
- Cannabigerol inhibits sodium conductance to reduce neuronal dorsal root ganglion excitability (2022) (0)
- Genetic Profiling of Sodium Channels in Diabetic Painful and Painless and Idiopathic Painful and Painless Neuropathies (2023) (0)
- High-throughput combined voltage-clamp/current-clamp analysis of freshly isolated neurons (2023) (0)
- Episodic Pain Syndrome Associated with a Novel Heterozygous Gain-of-Function SCN11A Missense Mutation (2019) (0)
- Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function (2023) (0)
- 76 NAV1.7 IS A THRESHOLD CHANNEL FOR PAIN (2010) (0)
- ResearchEffects of ranolazine on wild-type and mutant hNav 1 . 7 channels and on DRG neuron excitability (2015) (0)
- Nav1.7-P610T mutation in 2 siblings with persistent ocular pain after corneal axon transection: impaired slow-inactivation and hyperexcitable trigeminal neurons. (2023) (0)
- Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability (2023) (0)
- Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning (2018) (0)
- Figure 2. [The exon/intron boundary in the genomic sequence of SCN9A]. (2013) (0)
- Explorer Contactin-1 and Neurofascin-155 /-186 Are Not Targets of AutoAntibodies in Multifocal Motor Neuropathy (2015) (0)
- Alternating Electric Fields and Carcinogenesis: A New Paradigm to Avoid Missing the Elephant in the Room (2015) (0)
- Sodium channels and pain (dorsal root ganglion neurons/hyperexcitability/ion channels/nerve injury/inflammation) (2016) (0)
- Nav1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation (2023) (0)
- Fromthe ‡ DepartmentofNeurologyand § CenterforNeuroscienceandRegenerationResearch,YaleUniversitySchoolofMedicine, NewHaven,Connecticut06510,theRehabilitationResearchCenter,VeteransAffairsConnecticutHealthcareSystem,WestHaven, Connecticut06516,andthe DepartmentofDermatology,YaleUniversitySchoolofMedi (2010) (0)
- M4. Sodium Channels in Inherited and Acquired Pain Disorders (2010) (0)
- Conserved but not critical: Trafficking and function of NaV1.7 are independent of highly conserved polybasic motifs (2023) (0)
- Figure 1. [Red and swollen feet of an individual with SCN9A-related IEM]. (2013) (0)
- FULL-LENGTH ORIGINAL RESEARCH (2009) (0)
- 116 Exome Sequencing Uncovers Molecular Determinants of Trigeminal Neuralgia (2018) (0)
- Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits (2018) (0)
- Edinburgh Research Explorer Contactin-1 and Neurofascin-155/-186 Are Not Targets of AutoAntibodies in Multifocal Motor Neuropathy (2018) (0)
- EVALUATION OF MOLECULAR INVERSION PROBE VERSUS TruSeq ® CUSTOM-NEXT GENERATION SEQUENCING METHODS TO IDENTIFY GENETIC VARIATIONS IN PAINFUL NEUROPATHIES : THE PROPANE STUDY (2017) (0)
- Electron microscopic and reassociation kinetic analysis of inverted repeated sequences of the genome Cycas revoluta - by Sulayman Daoud Dib-Hajj (1982) (0)
- Table 1. [Summary of Molecular Genetic Testing Used in SCN9A-Related Inherited Erythromelalgia]. (2013) (0)
- Table 2. [Selected SCN9A Allelic Variants]. (2013) (0)
- Sodium channel blockers in the treatment of neuropathic pain (2019) (0)
- A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons. (2023) (0)
- Proteomics of voltage-gated ion channels (2010) (0)
- Plenary Session I: The Spinal Cord (2010) (0)
- TRPA1 rare variants in chronic neuropathic and nociplastic pain patients. (2023) (0)
- Non-psychotropic phytocannabinoid interactions with voltage-gated sodium channels: An update on cannabidiol and cannabigerol (2022) (0)
- Identification of a Novel Gain-of-Function Sodium Channel B2 Subunit Mutation in Small Fiber Neuropathy (2020) (0)
- Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain (2018) (0)
- The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy (2015) (0)
- Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation (2018) (0)
- Correction: Evaluation of molecular inversion probe versus TruSeq® custom methods for targeted next-generation sequencing (2021) (0)
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